LOCUS       DARYLJ010000001        84004 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYLJ010000001 DARYLJ010000000
VERSION     DARYLJ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84004
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..376
                     /locus_tag="TU746_000001"
     CDS             <1..376
                     /locus_tag="TU746_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL0890403.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TU746_000002"
                     /pseudo
     CDS             692..933
                     /locus_tag="TU746_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TU746_000003"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TU746_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL0890404.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TU746_000004"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TU746_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL0890405.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TU746_000005"
     CDS             6494..6823
                     /locus_tag="TU746_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0890406.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TU746_000006"
     CDS             6827..7261
                     /locus_tag="TU746_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL0890407.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TU746_000007"
     CDS             7263..7547
                     /locus_tag="TU746_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0890408.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TU746_000008"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TU746_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TU746_000009"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TU746_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL0890409.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TU746_000010"
     CDS             10025..10675
                     /locus_tag="TU746_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL0890410.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TU746_000011"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TU746_000011"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL0890411.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TU746_000012"
     CDS             12073..12813
                     /locus_tag="TU746_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL0890412.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TU746_000013"
     CDS             12810..14528
                     /locus_tag="TU746_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0890413.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HSKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TU746_000014"
     CDS             14567..15655
                     /locus_tag="TU746_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL0890414.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TU746_000015"
     CDS             15670..16374
                     /locus_tag="TU746_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL0890415.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TU746_000016"
     CDS             16634..17122
                     /locus_tag="TU746_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL0890416.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TU746_000017"
     CDS             complement(17632..18105)
                     /locus_tag="TU746_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0890417.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TU746_000018"
     CDS             18246..18926
                     /locus_tag="TU746_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL0890418.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
     gene            19195..20430
                     /gene="arcA"
                     /locus_tag="TU746_000019"
     CDS             19195..20430
                     /gene="arcA"
                     /locus_tag="TU746_000019"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL0890419.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            20440..20871
                     /locus_tag="TU746_000020"
     CDS             20440..20871
                     /locus_tag="TU746_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0890420.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            20886..21899
                     /gene="argF"
                     /locus_tag="TU746_000021"
     CDS             20886..21899
                     /gene="argF"
                     /locus_tag="TU746_000021"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL0890421.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            22061..23554
                     /locus_tag="TU746_000022"
     CDS             22061..23554
                     /locus_tag="TU746_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL0890422.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            23571..24902
                     /locus_tag="TU746_000023"
     CDS             23571..24902
                     /locus_tag="TU746_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL0890423.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            24920..25870
                     /gene="arcC"
                     /locus_tag="TU746_000024"
     CDS             24920..25870
                     /gene="arcC"
                     /locus_tag="TU746_000024"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL0890424.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            26090..27082
                     /locus_tag="TU746_000025"
                     /pseudo
     CDS             26090..27082
                     /locus_tag="TU746_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
     gene            27254..27793
                     /gene="rsmD"
                     /locus_tag="TU746_000026"
     CDS             27254..27793
                     /gene="rsmD"
                     /locus_tag="TU746_000026"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL0890425.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKLTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            27783..28283
                     /gene="coaD"
                     /locus_tag="TU746_000027"
     CDS             27783..28283
                     /gene="coaD"
                     /locus_tag="TU746_000027"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL0890426.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            28261..29298
                     /locus_tag="TU746_000028"
     CDS             28261..29298
                     /locus_tag="TU746_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL0890427.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            29860..30474
                     /locus_tag="TU746_000029"
     CDS             29860..30474
                     /locus_tag="TU746_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL0890428.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            30478..31560
                     /gene="rlmN"
                     /locus_tag="TU746_000030"
     CDS             30478..31560
                     /gene="rlmN"
                     /locus_tag="TU746_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL0890429.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            32842..33372
                     /locus_tag="TU746_000031"
     CDS             32842..33372
                     /locus_tag="TU746_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL0890430.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            33745..33978
                     /locus_tag="TU746_000032"
     CDS             33745..33978
                     /locus_tag="TU746_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL0890431.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            33953..34924
                     /locus_tag="TU746_000033"
     CDS             33953..34924
                     /locus_tag="TU746_000033"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL0890432.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            34934..35314
                     /locus_tag="TU746_000034"
     CDS             34934..35314
                     /locus_tag="TU746_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL0890433.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            35710..37551
                     /gene="typA"
                     /locus_tag="TU746_000035"
     CDS             35710..37551
                     /gene="typA"
                     /locus_tag="TU746_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL0890434.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            37633..37887
                     /locus_tag="TU746_000036"
     CDS             37633..37887
                     /locus_tag="TU746_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL0890435.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            38033..39394
                     /locus_tag="TU746_000037"
     CDS             38033..39394
                     /locus_tag="TU746_000037"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL0890436.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            39391..40473
                     /locus_tag="TU746_000038"
     CDS             39391..40473
                     /locus_tag="TU746_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL0890437.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            40474..41664
                     /locus_tag="TU746_000039"
     CDS             40474..41664
                     /locus_tag="TU746_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL0890438.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            41876..43240
                     /gene="ftsA"
                     /locus_tag="TU746_000040"
     CDS             41876..43240
                     /gene="ftsA"
                     /locus_tag="TU746_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL0890439.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            43264..44592
                     /gene="ftsZ"
                     /locus_tag="TU746_000041"
     CDS             43264..44592
                     /gene="ftsZ"
                     /locus_tag="TU746_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL0890440.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            44595..45266
                     /locus_tag="TU746_000042"
     CDS             44595..45266
                     /locus_tag="TU746_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL0890441.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            45279..45941
                     /locus_tag="TU746_000043"
     CDS             45279..45941
                     /locus_tag="TU746_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL0890442.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            45946..46203
                     /locus_tag="TU746_000044"
     CDS             45946..46203
                     /locus_tag="TU746_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL0890443.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            46200..46994
                     /locus_tag="TU746_000045"
     CDS             46200..46994
                     /locus_tag="TU746_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL0890444.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            47004..47759
                     /locus_tag="TU746_000046"
     CDS             47004..47759
                     /locus_tag="TU746_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL0890445.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            48030..50828
                     /locus_tag="TU746_000047"
     CDS             48030..50828
                     /locus_tag="TU746_000047"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL0890446.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(51306..51608)
                     /locus_tag="TU746_000048"
     CDS             complement(51306..51608)
                     /locus_tag="TU746_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL0890447.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(51670..52119)
                     /locus_tag="TU746_000049"
     CDS             complement(51670..52119)
                     /locus_tag="TU746_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0890448.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(52279..54531)
                     /locus_tag="TU746_000050"
     CDS             complement(52279..54531)
                     /locus_tag="TU746_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0890449.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            54813..55043
                     /locus_tag="TU746_000051"
     CDS             54813..55043
                     /locus_tag="TU746_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL0890450.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(55525..56463)
                     /locus_tag="TU746_000052"
     CDS             complement(55525..56463)
                     /locus_tag="TU746_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0890451.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQ
                     KSTLPATGETNHPFFTLAALSVITSAGVLNLKKKKS"
     gene            56805..57488
                     /locus_tag="TU746_000053"
     CDS             56805..57488
                     /locus_tag="TU746_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0890452.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            57490..58227
                     /locus_tag="TU746_000054"
     CDS             57490..58227
                     /locus_tag="TU746_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0890453.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            58671..60365
                     /locus_tag="TU746_000055"
     CDS             58671..60365
                     /locus_tag="TU746_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL0890454.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            60477..61331
                     /locus_tag="TU746_000056"
     CDS             60477..61331
                     /locus_tag="TU746_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL0890455.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            61328..62182
                     /locus_tag="TU746_000057"
     CDS             61328..62182
                     /locus_tag="TU746_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL0890456.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            62466..63806
                     /locus_tag="TU746_000058"
     CDS             62466..63806
                     /locus_tag="TU746_000058"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL0890457.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            63784..63999
                     /locus_tag="TU746_000059"
     CDS             63784..63999
                     /locus_tag="TU746_000059"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL0890458.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            63999..64868
                     /locus_tag="TU746_000060"
     CDS             63999..64868
                     /locus_tag="TU746_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL0890459.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            64861..65688
                     /locus_tag="TU746_000061"
     CDS             64861..65688
                     /locus_tag="TU746_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL0890460.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            65675..66145
                     /locus_tag="TU746_000062"
     CDS             65675..66145
                     /locus_tag="TU746_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0890461.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            66163..67824
                     /gene="recN"
                     /locus_tag="TU746_000063"
     CDS             66163..67824
                     /gene="recN"
                     /locus_tag="TU746_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL0890462.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVVAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            68045..68917
                     /locus_tag="TU746_000064"
     CDS             68045..68917
                     /locus_tag="TU746_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0890463.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            69055..69906
                     /locus_tag="TU746_000065"
     CDS             69055..69906
                     /locus_tag="TU746_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0890464.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            69899..70741
                     /locus_tag="TU746_000066"
     CDS             69899..70741
                     /locus_tag="TU746_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL0890465.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            70719..71306
                     /locus_tag="TU746_000067"
     CDS             70719..71306
                     /locus_tag="TU746_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL0890466.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            71404..71679
                     /locus_tag="TU746_000068"
     CDS             71404..71679
                     /locus_tag="TU746_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL0890467.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(71740..72444)
                     /locus_tag="TU746_000069"
     CDS             complement(71740..72444)
                     /locus_tag="TU746_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL0890468.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(72755..73963)
                     /locus_tag="TU746_000070"
     CDS             complement(72755..73963)
                     /locus_tag="TU746_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0890469.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(74018..74911)
                     /locus_tag="TU746_000071"
     CDS             complement(74018..74911)
                     /locus_tag="TU746_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0890470.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            75280..75453
                     /locus_tag="TU746_000072"
     CDS             75280..75453
                     /locus_tag="TU746_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890471.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(75498..76433)
                     /locus_tag="TU746_000073"
     CDS             complement(75498..76433)
                     /locus_tag="TU746_000073"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL0890472.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            76676..77371
                     /locus_tag="TU746_000074"
     CDS             76676..77371
                     /locus_tag="TU746_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL0890473.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            77480..78001
                     /locus_tag="TU746_000075"
     CDS             77480..78001
                     /locus_tag="TU746_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL0890474.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            78396..78935
                     /locus_tag="TU746_000076"
     CDS             78396..78935
                     /locus_tag="TU746_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890475.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            79074..79844
                     /locus_tag="TU746_000077"
     CDS             79074..79844
                     /locus_tag="TU746_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL0890476.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            79956..82010
                     /locus_tag="TU746_000078"
     CDS             79956..82010
                     /locus_tag="TU746_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL0890477.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            82022..82618
                     /gene="recR"
                     /locus_tag="TU746_000079"
     CDS             82022..82618
                     /gene="recR"
                     /locus_tag="TU746_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL0890478.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            82766..83812
                     /locus_tag="TU746_000080"
     CDS             82766..83812
                     /locus_tag="TU746_000080"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL0890479.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT        23629 a        15812 c        20144 g        24419 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctaagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat gcttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcactcta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gcaaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaagttttt
    18961 tgactttttt caatttataa atataagatt tttcgttaaa atgtaaaaaa caaacaagaa
    19021 aacgtataca aaaacataaa cattcatttt caggcgaaaa agtgtaatcg tttacacaga
    19081 ttggctgtga gaaataccct atttttgaat gctgcttgga gtaaactagg ggtgtaagca
    19141 aaagctaaga gtcttagcag tgaattcaca aaacattaga aagaggtaat tcttatgact
    19201 gctcaaacac cgattcatgt ttactctgaa attggcaagc tgaaaaaggt tttgctccat
    19261 aggcctggca aggaaattga aaacctgatg ccagactact tggaacgtct attatttgac
    19321 gatattccat ttttggagga cgctcaaaaa gagcatgatg cttttgcaca agcattacga
    19381 gatgaaggcg tagaggtgct ataccttgaa acactagctg ctgaatcact tgtaacacca
    19441 gaaattcgtg aagccttcat tgatgaatac ctaagcgaag ctaatattcg tggaagggca
    19501 actaaaaaag ctattcgtga gctactgatg tctattgaag acaatcagga attgattgaa
    19561 aaaacaatgg caggtgtgca aaaatcagaa ttgcctgaga ttccagcagc agaaaaaggc
    19621 ttgactgact tggttgaatc aagctatcct tttgcgattg acccaatgcc aaacctttat
    19681 ttcacacgtg atccgtttgc aactattggt acaggtgttt cgcttaacca catgttctca
    19741 gaaacacgca atcgtgaaac aatctatggt aagtacattt tcacacatca cccaatctac
    19801 ggtggcggca aggtacctat ggtttatgac cgtaacgaaa ccactcgtat cgagggtgga
    19861 gatgagctgg ttctttcaaa agatgtgctt gcagtaggta tctcacagcg gacagacgca
    19921 gcatcaattg aaaagctctt ggttaacatc tttaaacaaa atcttggctt caagaaggtt
    19981 ttggcctttg aatttgctaa caatcgtaaa ttcatgcacc tagataccgt ctttacaatg
    20041 gtggattatg ataagttcac gattcaccca gaaatcgaag gagatcttcg cgtttactca
    20101 gtgacctatg aaaatgaaga gcttcgtatt gtagaagaaa ctggtgattt ggctgagctt
    20161 ttagctgcta atctgggagt tgagcgtgtt gagcttattc gctgtggtgg tgataacctt
    20221 gtggcagctg gtcgtgagca atggaacgac ggctcaaaca cgctaacaat cgcaccaggt
    20281 gtcgtggttg tttataaccg taacactatt acgaatgcca ttcttgaatc aaagggcttg
    20341 aagctcatta agattcatgg aagtgaattg gttcgcggtc gtggtggacc tcgttgcatg
    20401 tcaatgccgt ttgaacgtga agacatctag gagaggcaaa tgacaagggt tattgttgga
    20461 aatcagcctt ttcaacgggc agctagctta tatattcgct atcaggtttt tgtcttagaa
    20521 cggcagattg atcggcaaga tgaatttgat tgcttcgacg ataacgatcg cgtgtatgca
    20581 gtcttgtatg atggtgatca gcctgtatcc acagctcgct ttttacccac agctaaagat
    20641 caggctcgtc taacaagagt tgctacgctg cgtcagtatc gtggtagggg ctatggtgcg
    20701 caggtgatag aagcgcttga gcagtatgcc agagagcaag cttacgagcg attggttatt
    20761 catagcgaga ttagcgcaca gtcattttat gaaggtcttg gctatcaagc ctttggcgag
    20821 ccttatgatg aagacggtga gccttgtcaa tcagtagaaa aatatttata aaaaggagaa
    20881 tttaaatgac acaagtattt caaggacgta gcttcttagc agaaaaagac tttacacgtg
    20941 aggaatttga atacctcatt gattttgcag cacacttgaa agaccttaaa aagcgtggta
    21001 ttccacatca ctatttagaa ggtaaaaata ttgccctctt gtttgaaaaa acatcaacgc
    21061 gcacacgtgc tgcctttaca actgcggcga ttgatttagg agctcatcct gaataccttg
    21121 gcgctaacga tattcagctt ggtaaaaagg aatcaacaga ggacacagct aaggtattgg
    21181 gtcgtatgtt tgatgggatt gaattccgtg gctttagcca acgtatggtt gaagaattgg
    21241 cagaattctc aggtgttcca gtgtggaatg gcttgactga tgaatggcac ccaacccaaa
    21301 tgcttgcgga ctaccttact gtcaaggaaa actttggtaa gcttgaaggc ttgaccttgg
    21361 tttactgtgg tgatggacgc aacaacgttg ctaattcact gttagtagca ggtaccttac
    21421 taggtgtgaa tgttcatatc ttctcaccaa aagagctctt cccagcagaa gacatcgtga
    21481 agctggctga gggctatgct aaagcatcag gtgcgcatgt gttagttact gacaatgctg
    21541 atgaggctgt aaagggcgca gatgtgcttt acactgatgt gtgggtgtca atgggtgaag
    21601 aagacaagtt tgaagagcgt gtgaagctct tgaagccata tcaagtgaac atggagcttg
    21661 ttaaaaaagc cgccaacgac aaccttatct tcttacattg cttgccagcc ttccatgaca
    21721 caaatactgt ttacggaaaa gacgttgctg agaaatttgg tgtagaagaa atggaagtaa
    21781 cagatgaggt cttccgcagc aaatacgctc gtcactttga ccaagcagaa aaccgtatgc
    21841 acactattaa agcggttatg gccgcaactc ttggtaatct tttcattcca aaagtgtaag
    21901 ctgtgattgg taccttttaa tttattttag ctcatttcat taatttaaca tttaactact
    21961 aaaaaacgta ctttaactac atgacgagtc gttctggttc tcgtgtcctt gaccggaact
    22021 gggacggctt atttttatga aaaggtaaga ggtaatcact atgacagaag aaaaaaaacg
    22081 aggttttaaa attccttctt cttacactgt tttgtttatc atcattgcta ttatggcagt
    22141 attaacctgg tttattccag ctggtgctta tgagactgct aaggatggcg gtgtgatttc
    22201 agggacctac caaacggtta agtcaaaccc tcagggcttt tttgacattt taatggcacc
    22261 tgttcgaggc atgctaggtg tcaaagggac tgaaggggca attcaggttt ctttctttat
    22321 tttgatggtt ggtggctttt taagggttgt caacaagaca ggtgcgcttg atacagggat
    22381 tgcttctgtt gtgcgtaaaa ataagggtag agaaaagctg cttattgcga ttttgattcc
    22441 tttgtttgca cttggtggca caacctacgg aatgggagaa gaaacaatgg cgttttaccc
    22501 tcttcttatt ccggtaatga ttgcggttgg ctttgatagc attgttgcag tagctattat
    22561 cctgattggt tcacagattg gctgtttggc ctcaaccatc aatccctttg ctactggagt
    22621 ggcagcagat gcagccggtg ttagtatcgc agatggtatg atttggcgga ttatccaatg
    22681 ggttgtcctt gttggtatgt ctatctggtt tgtttacagt tacgctagca agattgaaaa
    22741 agacccaagc aagtccttgg ttgctgacaa agctgaagaa cataaggaat tcttccagct
    22801 gcaaaattcc ggtgaggatt tgactagtcg tcaacgaaag gttttagcca tttttacctt
    22861 gacatttgtc atcatgattc ttagcttgat tccttgggaa gattttgaca ttcaattatt
    22921 tacaaatatc aacacttggc taacaacaac acctgtttta ggtggtatta ttggtaaaac
    22981 aatgggagcc tttggtactt ggtatttccc agaaattacc atgctcttta tcatgatggg
    23041 tgttttagtg gctgttgttt atcgcatgag tgaagatgac ttcttctcag cctttctaag
    23101 tggtgcaggt gagttcctcg gtgttgcgat tatttgtgcg gtagcgcgtg gtatccaagt
    23161 gatcatgaat ggtggtatga ttacagcaac cattcttcat tggggtgaaa caggtcttgc
    23221 aggcttgtca tcacaggtct ttgttgtctt ggcctatatt ttctatttgc caatgtcctt
    23281 cttgattcca tcaacatcag gacttgccgg tgcaacaatg ggaatcatgg ctccgcttgg
    23341 acaattctca aatgttcctg ctcatttggt tatcacagcc ttccaatcag catcaggtat
    23401 cttaaacatg atttcaccaa cctctgctat tgttatggga gcgctcgcac ttggacgtat
    23461 tgatctaggt acttggtgga aatttatcgg caagtttatc gttatggtaa tgcttgttag
    23521 tgttttgttg ttagtagtag cgacattctt ttaagagata ggaggctcct atggaaacct
    23581 atatccaacc aagacaccaa gaggcttgtg tagccgcgat taaaaaaata gtatcttacc
    23641 cttctgtgct aaatgagggg gaaaatgaca caccctttgg ccaagccatt caagatgttc
    23701 ttgaagcaac cttagccctg tgccaagatc ttggttttaa tacctatatt gatcctaaag
    23761 gctattatgg ctatgctgaa ttgggcgatc aaacagaggt gcttgctatc ctttgtcact
    23821 tagatgtggt gcctgctggt gatttgaagc tgtggcataa agatcccttt acttgtattg
    23881 aaaaagatgg ctgcttgtat ggacgtggca ctcaagatga caaggggcca tcgatgatgg
    23941 cactctttgc cactaaagca cttatggacg ctggtgtggt ctttaacaaa cgcattcgct
    24001 ttatctttgg aacagacgaa gaaaccctct ggcgctgtat gaaccgttat aatgaagtag
    24061 aggaggaggc aacctttggt tttgccccag actcaagctt cccattgacc tatgctgaaa
    24121 aggggctttt acaagctaag ctagttggta agggatcgcc taaactcaat cttgaggtgg
    24181 gtcaggccta taatgtcgtt ccagctagag cctcttatca gggagacaag ttggaggcat
    24241 taaaggaaga gcttgacagg cttggctttg aatatgttgt caaagatgac gagctaaccg
    24301 tctatggact tgctcagcat gccaaggacg ctccagatgg gattaatgcc cttatcaggc
    24361 ttgcaaaggc tcttgtagtg cttgagccag agccagtcct tgactttctt gctcatgtgg
    24421 ttgatgaaga cggcagagca gtcaatattt ttggtccagt tcaggacgag ccatcaggag
    24481 ggcttagctt caacgtagct ggtcttacct taacaaaaga gatgacagag attcgtttgg
    24541 acattcggat tccggtctta gcagataaag ataccttagt agaccagtta agccaaaaag
    24601 cgcaggacta cggtctagct tacgaggaat ttgattattt ggcaccctta tatgtgccct
    24661 tggacagcga gctagtaact accctgttag aggtatatcg taaaaaaaca ggggaccaat
    24721 cgccagccca atcatcaggt ggagcaacct ttgctcgtac aatggctaat tgtgtggcct
    24781 ttggagcatt atttcctgat gctgttcaaa cagaacacca agaaaatgaa catatcgtct
    24841 tagcagatgc ctatcgtgca atggatattt acgcggaagc catctaccga ctaacacgat
    24901 aagatgagga gtatcatata tgacaaaaca aaaaattgtt gtcgcacttg gaggaaatgc
    24961 aatcctctca acagacgcgt cagctaaggc acaacaagag gccttggttt cgacatcaaa
    25021 atcactagtg aagttaatca aagaaggcca tgaggtgatt atcacgcatg gcaatggtcc
    25081 gcaggttggt aatctcttat tgcagcaggc agcagctgat tctgagaaaa atccagccat
    25141 gccattagat acctgcgttg ccatgacaga aggcagcatt ggcttttggt tagtcaacgc
    25201 cctagacaat gagctgcaag cccaaggcat cacaaaggaa gtggcagcag ttgtcaccca
    25261 ggtcattgtt gatgaaaatg accctgcctt taaaaatccg actaaaccaa ttggtccttt
    25321 cttaaccgaa gaagacgcta aaaagcaaat ggcagaatca ggtgctagct ttaaggagga
    25381 cgctggtcgt ggctggcgta aggtggtgcc atcaccaaag ccaattggta tcaaagaagc
    25441 taatgtgatt agaagcttag ttgattctgg tgttgtggtg gtcagtgctg gtggtggcgg
    25501 tgtgccagtt gttaaagacc ctgcaagtaa aacgcttacc ggtgtggaag ctgttattga
    25561 taaagacttt gctagccaaa ccctttcaga attggttgac gctgatctct ttattgtctt
    25621 gacaggtgtt gataatgtct atgttaactt taacaagcct gatcaaagaa aattggaaga
    25681 ggtaacggtt tctcaaatga aggaatacat cgctcaggac caatttgctc ccggaagcat
    25741 gctgcctaag gtggaggctg caattgcttt tgtggaaaac aaatcaaatg ccaaagctat
    25801 catcacatcg ttagaaaata ttgacaatgt tctctcagca aatgctggta cacaaattat
    25861 cgcaggctaa ttcagatgac tgcacaatga gcttaggctt ttgtgctttg ataggtttta
    25921 gctgataagc ttgaaaaatt gatttaaaag gttaaattag gttaatttag ccttttcttt
    25981 tacttttaat cggtgtataa taagcgtaat atttttttat ttttactcat gattagaatg
    26041 gtaaaaaata aaggtgactt agtcgcgaaa atgatttaaa ggaggagcta tgaaaaaaag
    26101 ctttattcat caacaagagg aaatttcctt tgttaaaaat acatttacgc agtatttgat
    26161 tgctaagctt gatgttgttg aggtgcaagg tcctatttta agtagggtcg gagacggcat
    26221 gcaggacaat ttatctgggg ttgaaaatcc ggtatctgtc catgtcttga acattcctaa
    26281 tgcaaccttt gaggtggtgc attcgctagc aaaatggaag cgtcatacct tagcacgttt
    26341 tggctttaat gaaggtgaag gtcttgtggt gaatatgaaa gcgctccgtc ctgatgaaga
    26401 ttcgctagac cagacgcatt cagtgtatgt ggaccagtgg gattgggaga aggttatccc
    26461 tgatggtcag cgcaatctag cttacctcaa agaaactgtc gaaacgattt acaaggttat
    26521 ccgcttgaca gagctagctg ttgaggcacg ctatgatatt gaagctgtct tgccaaagaa
    26581 aattaccttc attcacaccg aggagcttgt tgccagatac cctgatttga caccaaagga
    26641 gcgtgaaaat gctatcacaa aagaatttga tgcggtattt ttgattggta ttggcggtgt
    26701 attgccagat ggcaagccac atgacggtcg tgcgccagac tatgatgact ggaccagtga
    26761 gtcagaaaat ggctaccatg gcttaaatgg tgatattctc gtttggaatg agtagctagg
    26821 cacagccttt gagctattct caatgggaat tcgtgttgat gaagaggctc taaagcgtca
    26881 ggtggacatt actggagatc aggaacgcct acaatttgat tggcacaaat cgctgctaaa
    26941 tggtctgttc cccctaacca tcggtggagg aattggtcaa tcgcgtatgg ccatgttttt
    27001 gcttcgtaaa aagcacattg gagaggtcca aacatcggtg tggccacaag aggttcgcga
    27061 tacctacgac aatattttat agatgatacg gaggctaggt ttttacctat agcctctatt
    27121 tttgtcccta agtgatgctt cattagagct catttagtgc taagcaggct cgtcagttat
    27181 ataataggtc aaaaatttga aaaaatgaat catttttaag gcttgacact agatttttgt
    27241 tataatatca gttatgagaa ttgtatcagg tgaatttgga gggcgtcccc taaaaacgct
    27301 cgaaggcaag actactcgac ccacatcaga taaggtacgt ggcgcgattt ttaatatgat
    27361 tggtccttat tttaagggcg gacgtgtctt agacttgttt gctggatcag gtggcctatc
    27421 aatagaggct atttctaggg gcatgtcaga ggcagtgctg gttgagcgtg atcgtaaggc
    27481 gcaagccatt atccaagcca atattaagtt gacaaaagct agccagcaat ttacgctatt
    27541 aaaaatgaac gctgagcgtg cacttgatca cttatccggt cagtttgatg tggtgttttt
    27601 ggacccacct tatgctaagg aaacgatagt agccaatata gaggccttgg tggagaaaaa
    27661 tcttttaagc gacgatgtga tgattgtttg tgagacggat cggtcggtag ctctgccaga
    27721 ggcaattgcc tggctaggga tctggaaaga aaaacaatat ggaattagca aggtaacagt
    27781 atatgtcagg taagattgga ctttatacag ggtcatttga cccagtgaca aatggacaca
    27841 tggatatgat taagcgtgct agccatttgt ttgagcatgt ttatgtcggg atttttaaca
    27901 atccaaataa gcagagcttt tttacttttg agctgcgagc tcaaatgcta agcgaagcgg
    27961 tttgtgcctt gccaaatgtg acagtggttt ctgccgagca tggtcttgca gttgacctgg
    28021 ctagggagct gtctgtgacc caccttatcc gagggcttcg caatacagct gattttgact
    28081 atgagatagg cttagagtat tttaatcata gactagcccc tgatattgag accatttacc
    28141 tgatggcgac tcatgacctg cagcccgtta gctccagtcg tatcagagag ttgattgcat
    28201 ttagagcgcc aattactggt ttggttccgc aggctgttat taatcaagtg gagaaaatga
    28261 atgaaaacaa taaaaaaaat taaatggtgg ctgattggct ttgttgcctt gctttttcta
    28321 ctgttgacac tgtttttccc cttgccttat tatattgaaa tgccaggtgg agcctatgat
    28381 attcgctcgg tattgactgt caatggcaaa gaggataagg aaaagggagc ttatcagttt
    28441 gttgtagtga gcctcagtcg ggccaccttg gctaaattgc tctatgcttg gctaacgcct
    28501 ttcactgaga ttagcaccat ggaagatact actggtggct atagcgatgc tgactacctg
    28561 cgaattaatc gcttttatat ggaaacctct caaaacagcg ctgtttatca ggcccttact
    28621 ctagcaggca aggaggtaag ctttgattat aagggtgttt atgtcttaga cgtcagcaag
    28681 gattctagct ttaaaggtgt gctgcaccta gcagatacag tgacaggtgt caatggtaaa
    28741 acatttacaa cgtctgccga tctgattgat tatgtttctc atttgacctt gggagatgag
    28801 gtgcaggtac aatttacaac cgctggtgag tcaaagactg aaaaaggaaa gattattaag
    28861 cttaaaaacg gtaaaaatgg gattggcatt accctgacag accacacaca ggtcatttct
    28921 ggtgatgagg tcgactttag cactggaggt gtgggtggac caagtgcagg cttgatgttt
    28981 actcttgata tttatgatca aatcaatcac gaagacttgc gcaagggacg tgtgattgct
    29041 ggtacaggaa ccattggcaa ggatggaaaa gttggagata ttggcggggc gggcctaaag
    29101 gtggctgccg ccgccgctgc tggtgctgat attttctttg ttccaaataa tcctgtgcat
    29161 aaggacgtca aaaaagcaaa tcctaaggct attagcaatt acgaggaggc taaaaaagca
    29221 gctaaacgac taaagacagc aatgaaaatt attcctgtga aaaccgttca agatgctata
    29281 agctacctta aaaaatagaa gcaatgcgaa gcaggctaat agggcatgct ctgtcttgct
    29341 tctagttggt ggaatttagc tagctcaaag gtcttgagac ctaagcataa ggtctagaca
    29401 gtattctaga gctagacctt atgcttgatc ctgaacaagg aagaccgcca aagaagaaca
    29461 aaatcctcag gccaaaagag cccgtaggga aatattgcca ttatctatca aggctttttg
    29521 aagaaaatca cttaaagaca gtagggcgtt aggctttact gtcttagttt ttcttgcctg
    29581 aagtcatggc tgctgatgat gttacatcaa ggcttactag ccagcagagc acaaggagca
    29641 gctttggctt aggtttattt tctctgctga ctagtaaaga aggttgctgt cagtctgctt
    29701 acaaaaacct aaaaatagtg tataataggt aggctatggg ctgtcaggag tcgctagcct
    29761 gcttacccag accagccctt tgagaagagc aagcatggct cttctcagaa taacccagga
    29821 ttaacagaca tcaaaattaa tgctaaggaa aggagctata tgaaaagaga tattttacca
    29881 gagatgtata attacaataa atttcccggt ccggaattta ttcattttga tcattatgtc
    29941 aaggctgaag gcattgagtt attgctgctg aaaaatgaaa aaaatgcttt taacacaacg
    30001 agctttggtc agcgcttcac agagatatta ttaaagtatg actatattgt tggagattgg
    30061 ggcaatgaac agctgcgtct caagggcttt tacaaggatc atcatgatgt caaaaaagct
    30121 agtcgtattt ctcgcctaga agactatatt aaagaatttt gtaactttgg ctgtgcctat
    30181 tttgttttgg aaaaccctaa tcccaaggac atgccaaaag aggaggaaag gccatcaagg
    30241 cgcaggaaat cgtctaaagc caatcgccgc agaaatcagc ctcagcatag tcagcaggca
    30301 cctgctaaag acaacttcaa aaagctaacc aaggataggt cagcggacaa gccaagcttt
    30361 accagcaaaa agcgcccagc tcctaataag accaagggaa accaaaggcg ctctcgtact
    30421 agtcaactga accataaaac ggatcacttt atcatcagaa agaaggacaa ttaatctatg
    30481 aaaccatcaa tctatggcct aacgcgcgac gagctaattg cttgggcgat tgacaatggt
    30541 caaaaggcat tcagagcgac acagatttgg gactggcttt acagaaaacg ggttcaatcc
    30601 tttgatgaaa tgactaacat ttctaaggaa tttgttgcca ttctaaagga cagcttttgt
    30661 attaatccct tgaagcagcg tgttgctcag gaatcagctg atggaacggt taagtatttg
    30721 tttgaattgc cagatggtat gctgattgaa acggttttga tgcgtcagca ctatgggcag
    30781 tcggtctgtg taactacgca ggttggctgt aatataggct gcaccttctg cgctagtggc
    30841 ttgattaaaa agcaacggga tttaaacagt ggtgaaatca ctgcacaaat tatgatggtg
    30901 caaaactatt ttgataagcg tgctcaagac gaacgtgtca gccatgttgt tgtgatgggg
    30961 attggagagc cctttgataa ttatcaaaat gtgatgacct ttcttcggac gatcaatgat
    31021 gatcatgggc ttgctattgg tgctcgtcac attactgttt caacctcagg cttggctcac
    31081 aagattcgtg aatttgccaa tgaaggagtc caagttaatc tggctgtgtc actgcatgca
    31141 cctaataatg agctgcgctc aagtatcatg aggatcaatc gttccttccc acttgataag
    31201 ctcttttcag caatcgaata ttacattgaa acaactaatc gtcgtgtgac ctttgagtat
    31261 atcatgctta ataaggttaa tgatggggta gagcaggcac aggaattggc agatttgacc
    31321 aaaaggattc gcaagctgtc ttatgttaac ctgattccct ataatcctgt ctcagagcat
    31381 gaccaataca gtagaagtcc taaggagcgt gtggcagcct tttatgacat tctaaagaaa
    31441 aatggagtga actgtgtcgt tcgtcaggag catggtacag atattgatgc tgcctgcggt
    31501 cagctgcgct ctaataccat gaaaaaggac cgacaaaaag cagcagctgc aaggacatga
    31561 tgacttggtc aaggttgctg atttgattga taggagatgg agataaaaat ctgacctcaa
    31621 ataaagcaaa caaataggtc tagttttctg agatcccgaa agcaggtctt gttcgttttt
    31681 taatgaatga gactaggtca taaagtacat gcgttaagaa tgtctaaagt gcagctcttt
    31741 ttgtcccagc ctccctcttt tatcttggta gcagttgtca agtaattgct aagcaacagt
    31801 gttttatctt tattggctgt aaaaaaagat atagtgcctt tattcacacc ttttctgaat
    31861 cacttgagcc ttgttctgac cgctcctttt ggtgcttctg atccatatag cctaagcttt
    31921 tcagagctat gaatcgaggc aaaataatag gtgttagccc tagctgcttg atgtagctag
    31981 ggcttttgtg acctagctgc cagtgagcct ttcaaatagc aatatggcta taaggcccag
    32041 tgtcagatag ggaataaaag ggattttctt agtttgtaga agtaggcagg ctagaattcc
    32101 gatcagactg gcaatttgga cgatccataa caaagagcta agcttgacca caagagcaag
    32161 attagctagg taaagaaaat ctccggcacc aatattgata ggaaaagcta cgcttagcag
    32221 tgcaagcaaa agcaatagca ctgttaacag gttaatgcta taaaatggca gcagaaacaa
    32281 aaagctcatc agccagatga gcaaaggata ctcttgactg tctaaatcaa aaaagcacag
    32341 tagcaaagag aagcatagga gataaagctg tgtccaggtc aagccgcaaa gggcagccag
    32401 tccgaaaatg aggctggtga ttatttctaa ataaggaagc ataacccagt gcttttgttc
    32461 atgcttagag ttgtaagtgg gctttgccat aggaaaaaag aggcttgaaa gatgaagttg
    32521 acctatatag agcttgaccc aagcctttgc ttgctgttca gaaaacaggt taagtattag
    32581 ccgaaagagg tttcccacaa gaaaaccaca atagcaataa aaaatagtgt tcatacttat
    32641 ttatccgaaa aacaatttaa attcttgcaa tattttaaaa aacggtgtac aatgaaacta
    32701 taaaacgaga atgattctaa ataagctgtt gatacttatc tgaattggct cgttatcgtc
    32761 gaatggagct gacaagagag tgacttttct tgctgcatac cattcatgcc cttttatatc
    32821 tatcagtaag gagagtttat tatgacaaac acactcgttg aaaacattta tgcatcagta
    32881 actcataata tttctaaaaa agaagcatca aaaaatgaaa aaaccaaggc tgttttaaat
    32941 caagcagtag cagatctatc tgtagcagct tcaattgttc atcaggttca ttggtacatg
    33001 cgtggtcctg gctttttata cctgcaccct aagatggatg agctattaga ccgcttgaac
    33061 gcgaacctag atgagatgag tgagcgcttg attactattg gtggggcacc ctactcaacc
    33121 ctagaggagt tttcacagca ttctaagcta gatgaaacaa agggaagcta tgataagtca
    33181 gtagctcagc atttagctcg tttggtagag gtttaccttt accttaccag tctttatcag
    33241 gttggtttag acattactga tgaagagggt gatgctgctt caaatgattt gttcacagca
    33301 gcaaaggctg acgctgaaaa gactatttgg atgctacagg cagagcgtgg tcaaggtcct
    33361 gctattttct aaagcgtcat acaactgata taacataaaa aaggcagagc gtggtatagc
    33421 cctgtctttt taacgccttt aaagtcagct attagtgcta gtgatgtcag gtctcacagc
    33481 ttttttatga tggatgacca acatttttag accttgtcac cacagcagag catgtggcat
    33541 ttagtccacc ttgggctcac gtcgatggtc ttacttatga tatatcaagg cttgtgacat
    33601 taccgttgcc ttttatcttc agtctgagct gctggttcct actgctgatg ctgcttgata
    33661 gtgttatagt gattttcaga aatatggaaa gcgattgcat aattgtcttg aaatctcatg
    33721 cgtaatttgc taaaatctag ttatatgaaa acattatacg atgtacagca gctgttaaaa
    33781 ggctttggta ttgttatcta catgggaaag cggctttatg atattgaaat gatgaaaata
    33841 gagctgcaaa ggctatatga tggtggcttg ttggataaac aggcttattt aactgctgag
    33901 ctgattttac gacgtgagca tcgattagag ctaaaaagag aagggcaaga aaatgagtca
    33961 aaaattgata gggattgatt tgggcggaac cacgattaaa tttggtattt taacctcaga
    34021 gggtgacgtt caggaaaaat gggcgattga gacaaatgtt ttagaggacg gtaaacatat
    34081 cgttccagat attgtcgcct cactcaagca tcgccttgac ctttatggac tgactaagga
    34141 cgattttatc ggtattggta tgggctcacc tggagctgtc aatcgcacag atcatactgt
    34201 tacaggggcc tttaacctca actggagagg cacccaagag gtgggatctg ttattgaaag
    34261 ggagctagga attccctttg ctattgataa tgacgcaaat gttgcggccc tcggcgagcg
    34321 ctgggtcggt gcaggtgaca ataatcctga tgtggtcttt atgaccttag gaacaggtgt
    34381 tggtggtggt atcatcgctg atgggaactt gattcatggt gtggctggag ctggtggtga
    34441 gattgggcac atgatagtag agccgcttaa gggctttgct tgcacctgtg gctcacaggg
    34501 ctgcctggag acagtggcct ctgctacagg tgttgttaag gttgctcgtc ttttagcaga
    34561 agcctacgaa ggagattcaa gcattaaggc agcgattgat aatggagagg ctgtctcaag
    34621 caaggacatt tttgttgcag cggaggctgg tgatgccttt gccaactctg ttgttgaaaa
    34681 ggtcagttat tatctaggac tggcagcggc taatatctca aatattttga accctgattc
    34741 ggtcgttatt ggcggtggtg tatctgctgc gggtgagttt ttacgttcac gtgttgaaaa
    34801 gtactttatg acctttacct ttccgcaggt tagacagtcc actaaaatca aaatagcaga
    34861 gcttggtaat gatgctggta ttattggtgc agctagcctt gcaagacaat ttatcacaga
    34921 ataggagtta atgatgtcac cacttacaat gattggctgg gtattgcttg cgggagtgat
    34981 tgcctattac ctttggaatt atgtttccta tagaagaatg gcaaagcagg ttgataatga
    35041 tacctttaag gagctgatgc gtcaggggca agtgattgac ctgcgcgatc cagcttcctt
    35101 tagggcaagg catatcctag gcgctagaaa ttttcctgcc cagcagttta ctacctctat
    35161 taaggctttg agaaaggaca agccaatctt gctttatgaa aatgtaagac ctcaatatcg
    35221 ggtcaaagca gtcaaaacat tacgtaaggc tggctatacg gacctttatg tcctaaaagc
    35281 gggactagat tattggaatg gtaaggttaa atagccttat agtccttttt gctgagctaa
    35341 cgtttgctgc tatgtgtcgg aacgttgcaa gcagcagctt atctaagctt gtcatgctag
    35401 tttcacagcc caaagtggct ggccgtataa acgcagctgc ttttagatgc cggtaggagc
    35461 ttttgtcagc ttctttaggg attgttttaa gtgatgtaga gaggccgttc tgagagaaag
    35521 ccttgtagtt agaaaaagag atgagaaagc taaggctctt gctgctgttg taagagttag
    35581 ctttcttttt cttttttgtg tggcgcattt aagggcttga aaacatttac aattccctca
    35641 gatcggtttt ttaaaaaaat ttgtgttata ctgttttagt taaaactatt tatgctacaa
    35701 gaggaaaaaa tgacaaaatt tagagaagat attcgtaacg ttgctattat tgcccacgtt
    35761 gaccatggga aaacaacgct cgttgatgaa ttactaaagc aatcccatac actagatgag
    35821 cgcaaagagc ttcaagaacg tgcgatggat tcaaatgacc ttgaaaaaga gcgtggtatt
    35881 accattcttg ctaaaaatac cgcagtagct tataacgatg ttcgtattaa tatcatggat
    35941 actcctgggc acgctgactt tggaggcgag gttgagcgta tcatgaaaat ggttgatggt
    36001 gttgtccttg ttgttgacgc ttacgaggga accatgcctc aaacacgctt tgtgctgaag
    36061 aaggccttag aacaaaattt aaccccaatc gttgtggtta ataagattga taagccatca
    36121 gctcgtccag ctgaggttgt tgatgaggtt cttgagcttt tcattgagct tggtgcagac
    36181 gatgatcagc tggagttccc tgttgtttac gcttcggcga tcaatggcac atcttcgttg
    36241 tcagatgatc ctgctgatca ggaaaaaaca atggctccga tttttgatac cattatcgat
    36301 catattccag cacctgttga taactcagct gagccccttc aattccaggt gtcacttctt
    36361 gattacaatg attttgtagg tcgtattggg atcggtcgtg tctttcgtgg gactgttaag
    36421 gttggagatc aggtgacgct ttcaaagctt gatggcacca ctaaaaattt ccgcgttact
    36481 aagctgtttg gcttcttcgg gcttgagcgc aaggagattc aagaggccaa ggctggtgac
    36541 ttgattgcag tttctggtat ggaggacatt ttcgttggtg agacgattac accaacggat
    36601 tgtgtggagg ctttgcctgt tcttcgcatt gatgagccga cacttcaaat gaccttcttg
    36661 gttaacaact ctccctttgc tggtcgtgaa ggcaaatggg taacctctcg taaggttgag
    36721 gagcgtttgc ttgtggagct tcaaacagat gtgtcccttc gtgttgagcc aacagaatca
    36781 ccagataaat ggattgtgtc aggtcgtggt gagctgcatc tatctatttt aattgagacc
    36841 atgcgtcgtg agggctatga gcttcaggta tcgcgtccag aggttatcat taaggaaatt
    36901 gatggtgtca agtgtgagcc ttttgaacgt gtacagattg acacaccaga ggaatatcaa
    36961 ggtgctatta tccaatcctt gtcagaacgt aagggggata tgcttgatat gcagatggtt
    37021 ggtaatggtc aaacgcgtct tatttttctc attcctgccc gcggcttgat tggttattcg
    37081 actgaatttt tatcaatgac acgtggctat ggtatcatga atcatacctt tgatcagtat
    37141 ctgccagtgg ttgctggtga gattggtgga cgccatcgtg gagcgctggt ttcgattgaa
    37201 aacggtaagg caacaaccta ctcaatcatg cgtattgaag agcgcggaac aatctttgtt
    37261 aacccaggaa ctgaggttta tgagggcatg attgttggtg aaaattctcg tgacaatgac
    37321 cttggggtta atatcacaac tgctaagcag atgaccaacg ttcgttcagc aacaaaggat
    37381 cagacagctg ttatcaaaac accacgtatt ctaacccttg aggaatctct tgaattcttg
    37441 aatgatgacg aatacatgga ggtaacgcca gaatcaatcc gcttgcgcaa gcaaattttg
    37501 aacaaagcag cgcgtgataa agctaataaa aagaaaaaat cagcagaata aaggctggtt
    37561 ggtctgagca tcacactccc ttgccgcttt aactagtaag ctaggttggc agaggattga
    37621 aaggagcttt ctgtgtttta tcttattatt gcagccttga ttacctctta ttacctgttt
    37681 atggcaccaa agagcgtccg taacacacta ggtatgattg gtttggttgg tttggttgcc
    37741 ctattgattg tgctagctgg cttaagtttt atcaaaatca tgcaaacgcc caaggaaatt
    37801 ttcgttggtc tagccatgat agtattgggc tactatgccc taagggacat tcaaaaaatc
    37861 cctaaaaaac caaagagtaa acattagcat caagcattga gtcaaatctt aatagggttt
    37921 gactttttct gtctttgtac tggccttatg cgctgctatc tgtaaaatct tgaaaaagca
    37981 gttaaataag ggtaaaatag tagtcaaata gacatagata gtgtggataa aaatgaagac
    38041 aataacggaa ttccaaaata aaaaggtatt gattcttggc ctggccaaat cgggcgaagc
    38101 agcagctagg cttttagccc ggttgggagc tattgtgaca gttaatgata gcaagccctt
    38161 tgaggaaaat cccgcagcac aggctcttct tgaggagggc ataagggtta tttgtggtag
    38221 ccaccccttg gagctgttag atgaagactt ttattgtatg gttaaaaacc cagggattcg
    38281 ctatgacaac ccgatggtgg tacgcgcctt agataaggct atttctattc taacagaggt
    38341 tgagctggct tatttggtat ctgaagcacc tatcattggt attacgggct caaatggtaa
    38401 aaccactaca accacaatga ttgctgatgt gctaaatgct gggaaccatt cagctctttt
    38461 ggctgggaat atcggctttc ctgcttcaga ggtggctcaa gctgctacag caaaggatat
    38521 actggtcatg gaattgtctt cctttcagct gctggggact gagcagtttc agccacatat
    38581 tgcagtcatt actaacctag tgcctactca tcttgattat catgggagtt ttgaggacta
    38641 tatagcggcc aagtggcgca ttcaacatcg aatgaccgat aaggattacc ttgtgttaaa
    38701 tgctgatcaa gagctggtaa aatcattggc tcaaaagact aaagcaagtc ctgtcttttt
    38761 ttctaccaaa gaaaaagttg atggtgctta tttggcagat gggtatcttt atttcaaaga
    38821 ggagaggctg atgtcagcag ctgagcttgg tgttcctgga aggcataaca ttgaaaatgc
    38881 tcttgccacc attgctgttg caaagctaag aggcatttct aatcaagtga tatcaaggac
    38941 tttgtctcac tttagggggg tgaagcaccg ccttcagtta gttggtacat tgaatcaagt
    39001 gaccttctac aatgacagca agtcaaccaa tatcttggct tgtcaaaaag ccttgtcggg
    39061 ctttgataat agcaaggtta tcctgattgc tggtggcttg gatcgtggca atgaatttga
    39121 tgagctggtg ccagacctcg ttggtcttaa aaagatgatt cttttagggg aatccgcaga
    39181 gcgtatgaag cgagctgcag acaaggcagg agtgtcctat cttgatgcca aagatgttgc
    39241 agctgccact aaaatagcct ttgagcaggc aaaggctggt gatattatct tgctgagccc
    39301 agccaatgct agctgggata tgtatccaag ctttgaaagc cgcggcgacg agtttttagc
    39361 agcctatgac gcgttaaaag gagaggctca atgaccaaga aaatcatttt taccggtggt
    39421 ggaacagctg gtcatgtcac tttaaacctt atcctcatac cgaagtttat caaagatggc
    39481 tgggaggttc actatattgg tgatgacaaa ggcattgagc atcaggagat caaaaagtca
    39541 ggtcttgatg tcacctttca tgctattgca actggaaaat taaggcgtta tttctcttgg
    39601 caaaacctgc ttgatatctt caaggtaggc tttggtgtca tgcaatcact ttttatcata
    39661 gctagactaa ggcctaaggc tctcttttca aagggaggct ttgtgtcggt tcctcctgtg
    39721 attgctgcaa ggcttttagg ggtgccggcc tttattcatg agtcggatct ttctatgggc
    39781 ttggctaata ggattgctta tcggtttgca acaacgatgt atacaacctt tgagcaagag
    39841 cagacactgg caaagctcaa gcatgttgga gcggttacca aggtgacagg tcctgggagt
    39901 cgatcggtga cttctaagca gcttgaagct gttttggagt attttgatcc taatttaaaa
    39961 acacttttgt ttattggagg ctccgcaggg gctagggtgt ttaaccgctt tatcactgac
    40021 catcctgagc taaaggaaga ctttaatatc atcaatatct ctggcgatcc tagcctaaat
    40081 gagcttagtt ggcatcttta ccgcgtggat tatgtgactg atctgtatca accgctcatg
    40141 gaaatggctg atctggtagt gactcgcgga ggctctaaca cactttttga attattagcg
    40201 atgagaaagc tccagcttat tatcccactt ggcaaagagg ccagtcgagg tgatcagctt
    40261 gagaatgctc attattttac aacaaggggc tatgctgagc aattattgga gcaggaattg
    40321 accctgcctc attttcaaga gaaagtgaga gaagtctttg ctaagcaatc ggactattta
    40381 tctgcaatga agagctctag cgagctccaa tcaccagaaa gcttttacca gcttttaagt
    40441 gccgacatta gctccgcgac aaaggaaaat taaatggcag ataagacaaa acattcagaa
    40501 gaaaaagccg ctttgaccga atggcaaaag cgtaatattg aatttctcaa caagaagcag
    40561 cagcaggctg agaaagacaa aaaactaaaa gaaaaattat taaatgagaa aatagcgcaa
    40621 gctcagggag aggcagcttc aaaggctgac caagaagata cagatgaagc tgaggagaaa
    40681 actgaggtaa gccaagcggg tactgatgag ggtgagccgc tgccagaagc atcagagcag
    40741 gaagtcccct ccccaaaaga caagccatta aaagtcccca aagaaaaaag tccaaagcag
    40801 caggcacttc aaaagggctg gcctgtattg ctggtgtcgt ttgtggtttt gtgcctgtcg
    40861 atttttatga tcacacccta tagtaaggtc aaggatttct ccgtcaaggg caataaaaaa
    40921 acaagcgttg aggacttagt tagagacagt gggatcaagt catctgatta ctggattact
    40981 ctattagcct ctccgggttc ttatgaaaat gcggttttaa aagccaatcc ctgggtgaaa
    41041 aaggtggctt tgcgttacgg ctttcccaat catttccgct ttgatgtgac agagtttgat
    41101 attattgcct acgctcaggt agctgaaggg tttcaactga tcctagaaaa tggcaagcga
    41161 gttgctgctg tcaagcaggc tgctttgcct aaatcctttt tgattttaaa tcttgagcat
    41221 gaaaaagaga ttcaagatgt cattaatcgc ttgaccaaaa tcccaagtga cctagtcaag
    41281 gctatcaaat cagtgtcatc ggccaattca cagacaacta aggatttgct gcttcttgaa
    41341 atgcacgatg gcaaccttat cagggtacct cggtcacagc ttgagctaaa gctgccttat
    41401 taccaaaaaa tcaagaagaa tcttgatact gctagcattg ttgatatgga ggttggtatc
    41461 tatacgacca ctgctgaaat tgaaaacatg cctgaggtgc cagcgtctgc tcaagcttct
    41521 caggcagata agcctgctga ggcttcacca gagcagggtg aagagcaggc cacacaggag
    41581 cagcctagcc ctgaaacacc tgctaatcct gaggccacaa atccctcagt cgcccagcct
    41641 actgagcagg caaatcaaca gtaatcgttt agggtaagag aagggggcaa aaaagcattt
    41701 aaggctctta aattaggccc ttgttgaacg gcaaaaaaac attaagttta tataacaaaa
    41761 aacgtaaaat ggtaacattt tacgtttttt tatgatataa tattccctga ataattctgc
    41821 tttttagcag tgtttttgaa tagtaaaagt ttggaaagta agtgaggtcg agtgaatggc
    41881 tagaaatggc ttttttactg gtttggacat tggaacaagc tcgataaagg ttttggtagc
    41941 agagtttatc tctggcgaga tgaatgttat tggtgtgagc aatgttccga gtactggcgt
    42001 aaaagatggc ataatcattg atatagaggc agcagccgct gctattaaaa ctgcagtaga
    42061 acaagctgaa gaaaaagcag gaatgacaat tgaaagggtc aatgttgggc tgccagcaaa
    42121 cctccttcaa attgagccga cacaaggcat gattcctgtt cctagcgaat caaaagaaat
    42181 caaagatgaa gacgttgata gcgttgttaa gtcagcacta actaagagca ttactccaga
    42241 gcgagaggtg atttccttag tccctgaaga gtttattgta gacggctttc agggcattcg
    42301 agatcctcgt ggcatgatgg ggatcaggct tgaaatgcgc ggtctgattt acactggacc
    42361 aagcacaatc ctgcataact taagaaagac agttgagcgt gctgggatta aggttgaaaa
    42421 catcatcatt tctcctttgg caatggctaa ggcggtgtta aatgaaggtg aacgtgaatt
    42481 tggtgctacg gtcattgaca tgggtggagg acaaaccacc gttgcctcaa tgcgagcaca
    42541 ggaattgcag tacaccaata tctatgcaga gggtggcgag tatatcacaa aggatatctc
    42601 taaggttctt aaaacgtcaa tgtcaattgc agaggccttg aagtacaatt ttgggcaggc
    42661 tgatatggca gaggcaagct tgactgacac tgttaaggtt gatgttgttg gcagtgatga
    42721 gccagttgag gtaacagagc gttacttatc agagattatc tcggctcgtg ttcgccatat
    42781 tctagatcgt gttaagcagg atttagaaag aggacgcctg cttgatttac ctggtggcat
    42841 tgtgctgata ggtggcggcg ccattatgcc gggcgtggtt gaggttgctc aagagatttt
    42901 tggaaccaat gttaagcttc atattccaaa tcaggttggt attcgtaacc caatgtttgc
    42961 caatgtcatt agcttggtcg agtacgttgg tatgatgtca gaggtggacg ttttagcgca
    43021 aaatgctgta tcaggcgagg aattgctaag acgtaagccg atcgacttta ctggccaaga
    43081 agcttacttg ccagactaca atgagactag gggatttgaa ccggctccta attatgagca
    43141 gcaagtgccc caagcagact acgagcctca agaacccgct gaaccaaagc aaaagatttc
    43201 agagcgtgtt cgtggcattt ttggaagtat gtttgattaa aagtaataaa gtgaggaaat
    43261 aaaatggcat tttcatttga tacggcatcc attcaaggtg caatcattaa ggtaatcggt
    43321 gttggtggag gtggcggaaa cgctattaac cgcatgattg atgagggggt tgcaggtgtt
    43381 gagtttatcg ctgcaaacac tgatattcag gcattaagct catcaaaagc agaaacagtt
    43441 gttcagcttg gtcctaaatt aactcgtggt cttggtgctg gaggtcagcc agaggttggt
    43501 cgtaaggcag cagaggaaag cgaagaggtt ctcacagaag ctttgactgg cgctgatatg
    43561 gtctttatca ctgctggtat gggtggaggc tctggaacag gagcagctcc agtgattgct
    43621 cgtatcgcta agagcctagg agccttgact gtggcagttg taacacgtcc atttggcttt
    43681 gaaggcaaca aacgcagtaa ttttgccatt gaggggattc aggagctaag agagcaggtt
    43741 gataccttat tgatcatctc aaataataac ctgcttgaaa ttgttgacaa aaagacacca
    43801 ttgcttgaag cgcttagcga agcagacaat gttttgcgtc agggtgtaca agggattact
    43861 gatctgatta caagccctgg cttgattaat cttgactttg ccgatgttaa gactgtgatg
    43921 gcaaataaag gcaatgcact tatggggatc ggtattggtt ctggtgagga acgtattgta
    43981 gaggcagctc gtaaggctat ctactcacca ttacttgaaa caacaattga cggtgctgaa
    44041 gatgttatcg ttaacgtgac aggtggactt gatatgaccc tcacagaggc tgaggaggca
    44101 tctgaaattg ttggtcaggc agcaggtcaa ggcgttaaca tctggctagg aacatcgatt
    44161 gatgactcta tgagagacga aattcgcgta acagttgttg caacaggtgt tcgtcaggat
    44221 aaggcggagc aagcctcagg atttcgtcag ccacgcacct acactcagtc taacgctcag
    44281 caggctgctg gagcacaata tgcttcagag caggtgagac agactgcgca gccaagcttt
    44341 gatcgtcgtt catcaagctt tgattttgat atgggtgaaa cacgtgagat gcctaagtct
    44401 cagcaagcta tgccagctca tggccacaat cataatcagg gctcagcttt tggaaattgg
    44461 gacttacgtc gagacaatat tgctcgtcca gcagaaggtg agcttgacaa tcaattgaac
    44521 atgtcaacct tctcatcaaa tgatgacatt gatgatgaat tagaaacacc accatttttc
    44581 aaaaatcgtt aatgatggat ttacaaaaaa ataaggatat tgtttttgaa aatattcgct
    44641 tagccactca ggcagccaac cggcctgaaa acagtgtgtc agttatcgct gtcacaaaat
    44701 atgtggacaa ggcagttgca ggtcagctga ttgatatggg gattgagcat atcgctgaga
    44761 accgtattga taagtttcta gataaatatg aagccttgaa agataggcaa gttacttggc
    44821 attttatcgg tactttacag cgtcgaaagg taaaggaagt gattaataag gttgattatt
    44881 ttcatgcctt agattcagta aaactggctt tagaaattga aaagagagct gaccaccctg
    44941 tgaagtgttt tctacaagtt aatatttctg aagaagaaag caagcatggt tttaagattg
    45001 ctgagcttga tgctgctatt gaggaaatca gcaagatgga aaagcttcat cttgtcggta
    45061 tcatgacaat ggcacctatt gatgccagtc agcaagagct tagaagcatt ttccaaaaag
    45121 caaatcaatt aagaaaaaac ttgcagtcaa aaaagagaaa gaatatgccg tttacagaat
    45181 tgagtatggg catgagtaac gattatccaa ttgctattca agaaggctca acctttgttc
    45241 gtattggaac atctttcttt cactaaatgg agaataagat ggcaattaaa gacgcattta
    45301 ataagatgat ttcttatttt gatactgatg gggtcagtga agtagaagag gagctatcct
    45361 ctaaaaagca agaagagcct gtgactaaat cacaacagac cagcagacct aatcagcagc
    45421 aacaagcagc tagagcgagt cagccccagc agcctaagca ggctagacct cagatgcaag
    45481 ctcagcaaag accacaatca caatcaagag ctgcctatgc tgagcgacca tatcaaggtc
    45541 aaagtcaagc acgtgtttct catgactaca atgacagaag ggcgacgtca gccccgtctg
    45601 cttctagtcg tcgtgagcaa tatcagcatg ctgctcatca agagcaaaca actattgcct
    45661 tgaagtatcc tcgtaagtat gaggacgccc aagaaattgt tgatcttttg attgttaatg
    45721 agtgtgtgct gatcgatttt caatacatgc tagatgctca ggcaaggcgt tgcctagatt
    45781 ttattgacgg tgctagtaag gtattgtatg gtactctgca aagggttggt tcttccatgt
    45841 atctgttgac cccatcaaat gtatctgtta atattgaaga gatgaatatc ccaaataatg
    45901 gccaagatat tggttttgat tttgatatga agagacgcta gtgtgatgat ttttatactg
    45961 ttgatacttc taaagctaat taaggtttat tcctatttgc tgctagtcta tgccttactg
    46021 tcttggtttc ctggagccta cgactcttgg cttggcaggc tggtcagcga tatagtagag
    46081 cctatcttaa aaccctttag atcattgaac ctacagtttg cgggcttgga ctttactatt
    46141 tacctagtga tgattggtct aaatgtttta agtgagatct tgataagagt gttgatctca
    46201 tgactgttca aacaatgctt tatcagcatt ttcagcctga tgaacaccca tttattgaaa
    46261 gaatgcttga cttgatcgct cgtgttgagg ctaattattt attagaggtt actgattttt
    46321 taaatccgcg agaggtcacg attttaaaag gcttagtcgc agcaaccaat ctgcagtgct
    46381 ttagctctac tgattattat cctagtgaat atggtcgtgt gattgttgct cctgactatt
    46441 attgtctaga taaggcagat tttgacttgg ctttgattga ggtgacctat aatgctaagt
    46501 ttaatcagct gacacatgca cagattttag gcaccttaat taatgaattg ggaatcaaaa
    46561 gagccttact tggcgatatt tttgttgaga taggtcatgc tcaggtcatg attaatcgac
    46621 agctgttaag ctattgttta ggaacgattg ctaaaatagc aaaagctagg gtcaagctca
    46681 aagaaattga tcttgatcag ctgttaaatc tgacagctaa tcagcaggtt ctgactgata
    46741 taatggtatc tagtctacgc gttgatcgct tgattgctac cgtattaaag caatctagaa
    46801 atcaggcgat aaggcttgtt gaagcaggca aggtcaaggt taactatcag cttgtcacta
    46861 aagcctctca gcctgtagct gttggtgatt taatcagcat tcgtggctac ggtaggttta
    46921 gcatactaac agacaatggc ttcacaaaaa atgggaaata taagctaaca cttagcaaaa
    46981 tgatgcgtaa ataaggagat ataatggcac ttacagcact agaaattaaa gataaaacgt
    47041 ttaagacaaa gtttcgtggc tacagtgaag aggaagtaaa tgaatttctt gagattgttg
    47101 tagacgatta tgaggctttg gttcgcaaaa atcgtgataa tgaagctaag ataagagagc
    47161 ttgaagaaaa gctgtcttac tttgatgaga tgaaggaatc attgagtcaa tctgttatcc
    47221 tagcccagga aacagctgaa aaagtgaaat cctcagcaaa tgctgaagca accaatttgg
    47281 tcagcaaggc aacctatgat gctcagcatt tacttgatga gtcaaaagca aaggctaacc
    47341 aactgttgcg cgacgcaaca gatgaagcaa agcgcgttgc tattgagaca gaggaattaa
    47401 agcgccagac acgcgttttc catcagcgct tggtttcagc tattgagtca cagctaagct
    47461 tatccaattc gcctgagtgg gacgaattgt tgcagccaac agctgtctac cttcaaaact
    47521 ctgatgcagc ctttaaagag gtggttaaaa ctgtccttaa tgaagatatt cctgaggctg
    47581 atgacagcaa ttcctttgat gcaacacgtc agtttacacc agaggagcta gaggagctgc
    47641 agcgtcgtgt tgaagaaagc aataaggagc tagaagccta tcaggtgcag cgagaagagc
    47701 aagctagcga gcctgaagtg aacctaagcg agacacagac ctttaaattg aatatttaat
    47761 cataagaaaa acaggattga atgcccaaaa tcacagcaag taggagatga tgagagtcct
    47821 atattccctg agcatgacaa ttatcatttt cttcaatcat cactgaatga cagtaagtga
    47881 cgagggaggc tcaccttacg agcaaagagg gaacagcaaa agggatttta ctgttctgaa
    47941 ttaaggtggt accacgagct ttcgtccttt ttgagacggg gctttttttg taattctgat
    48001 aagatattga ctaaaaggag tttgacaaga tgaaattaaa agaaacactt aacttaggca
    48061 aaacggcctt tccaatgcgt gccggtctac ccaacaagga gccacaatgg caaaaggctt
    48121 gggacgaggc tgagatttac aaaaaacgtc aagccttaaa tgaaggcaag cctgcctttc
    48181 acctgcacga tgggcctccc tatgcaaatg gtaatatcca tgtcggacat gcgctgaata
    48241 aaatttcaaa agacattatt gtacgtgcca aatctatgtc aggctatcaa gcgccttttg
    48301 ttccaggttg ggatactcat ggccttccta ttgagcaggt cttggctaag cagggggtta
    48361 agcgtaaaga gatggatctg gctgactatc ttgacatgtg tcgtcagtac gcgttaagtc
    48421 aggttgataa gcaaagagac gactttaagc gtctcggtgt atctgctgat tgggacaatc
    48481 cttatgttac cttagatcca agctttgaag ccgatcaaat tcgtgtcttt ggtgcgatgg
    48541 ctgataaggg ctacatttat cgtggggcaa agcctgtgta ttggtcatgg tcctctgaat
    48601 ctgctcttgc tgaggcagaa atcgaatacc atgatattga ttctacatcg ctttactatg
    48661 ctaatagggt taaagatggt aagggaatcc ttgatactga cacctatgtt gtggtttgga
    48721 cgaccacacc atttacggta acagcttctc gtggtctaac agttggacct gatatggatt
    48781 atgtggttgt tagacctgca ggttcagacc gtaactatgt ggtggcagaa ggactgctag
    48841 acagtctggc tgctaagttt gcttgggaat catttgagat tttggccaat cataagggct
    48901 ctgacttgga atacattgta accgagcacc cttgggacag tgaggttgat gagctagtca
    48961 ttcttggcga tcatgtgacg ctagattcag gtacaggtat cgttcataca gcacctggct
    49021 ttggtgaaga tgactacaac gttggtatga catatggact tgaggttgca gttacagttg
    49081 atgagcgtgg tttgatgatg gaaaatgcag gtcctgattt tcatggtcaa ttttatggca
    49141 aggtaactcc gattgttatt gaaaagcttg gagacctatt gcttgctcaa gaagtgatca
    49201 accactccta tccatttgat tggcgcacga aaaaaccaat tatttggcgg gctgttcctc
    49261 agtggtttgc ttctgtgtct gacttccgtc aagagattct agatgagatt gacaaaacaa
    49321 cattccaccc gacatgggga aagacacgac tctacaatat gattcgtgat cgtggcgatt
    49381 gggtgatctc tcgtcagcgt gcttggggtg ttccactgcc tattttctat gcagaggacg
    49441 gcacagccat tatgactaag gaggtaactg atcacgtcgc agatctgttc caagagcatg
    49501 ggtccattat ttggtggcaa aaagaggcta aggagctttt acctgaaggc ttcacacacc
    49561 caggctctcc aaatggggta tttaccaaag agacagatat catggacgtc tggtttgatt
    49621 cagggtcttc ttggaatggt gtgatgaatg ctcgtgatca tcttgcttat ccagctgacc
    49681 tctaccttga gggctccgat caatatcgtg gttggttcaa ctcatcactg attacctcag
    49741 ttgcggttaa tggtcatgca ccgtataagg ctatcctatc acagggcttt gtccttgatg
    49801 gtaagggtga aaaaatgtct aaatctaaag gaaatatcat ttcacctaat gatgttgcaa
    49861 agcaatatgg tgctgatatt ctccgtctct gggtagcttc tgttgataca gataatgatg
    49921 tgcgtgtgtc aatggatatc ctaggacagg tctctgaaac ctatcgtaaa atccgtaaca
    49981 cgcttcgctt cttgcttgct aatacatcag acttcaatcc acatacagat aaggtggctt
    50041 atgctgagct tgctgctgtt gataagtaca tgaccatcaa gtttaacaag ctagtaggag
    50101 ctatcaatac tgcctatgag cgttatgact tcatgacgat ttacaaggct gtggttaact
    50161 ttgtgacggt tgacttatct gctttctacc ttgattttgc caaagatgtg gtctacattg
    50221 aggctgctaa cagcctggca cgtcgtcgta tgcagactgt cttttatgat attttggtta
    50281 atatcactaa gctattgact ccgatccttc cacatacggc agaggaaatc tggtcatatt
    50341 tagagcatga gccagaagac tttgtacagc tatcagagct gccacaggct cagacttttg
    50401 ataatcaaga tactatccta gaggaatggg aagcctttat gacgcttcgg gcacaggcgc
    50461 aaaaggcttt ggaggaagca cgtcatgaca agattattgg taagtcctta gaagctcatc
    50521 tgacaattta tgcaagtcca gaggttaaga cactgttgac agctctagat agcgatattg
    50581 cactgctatt gattgtctct cagctaacca ttagtgagga gccagctcct gagaatgctg
    50641 tcagctttga tgatgttgcc tttacggtag ctcgtgcgca aggagaggtt tgtgagcgtt
    50701 cacgtcgtat cgatccaacg accagaatgc ggtcttataa tgcctttgtt tgtgaccaca
    50761 gtgcgaaaat tatcgaagaa aacttcccag aagcagtagc agaaggcttt gactcagctg
    50821 ctaattaagc aactaacagc tctgttcccg agttaaataa gcattggcgt gcttttgcca
    50881 atccagcagc aaggtgctag tcggtctggg cgtacctgcc ttactaggga ctctttgtgt
    50941 gggagctgat aagtgacctg ccttgagctt ggcaggtcta ggcttcttta taggttcacg
    51001 atttacgatt gactgggctt agagaagggc tagtcctgct aggcggcatt ggatatgaac
    51061 tgagtagtca tcatagctat aaaaaaacaa gcgcagactc acgtcagctt aatcgtgagc
    51121 ggcgcttgtt ttttcttggt tggggggtga aggcgaggag ctattaaagc taatattaag
    51181 cgatcaaaaa agcctagacc actagtcatg ttgtctaagc ttcagctgtt agagaggagc
    51241 tttctgagtg gaaggtagcc tatgctgata ggtgctgcct tagcctttta gcagtagtat
    51301 taaggctaga cagacgtctg gaaggaaatt tcaatcaaat tattggtgtg cagggttttt
    51361 gagtgacctg gaatcacaat agattggtca atcttacgct ttaagaaaaa ttcgcgaatc
    51421 acttcaagct cgtcctcttt gatggcacga tatttatttg aaatgagtag ctcataatgc
    51481 ttgggtgctt gcgtaaagat gacgtcagtg ttaccagctg agtaaacttc aacgaggtga
    51541 gcatctgtat tttgcagctg atttctgaca agctcggggt gactgctggt ggtattaata
    51601 agtctcataa atcttctcct gactattttt acttttatta tagcactatt tttaaattga
    51661 ttacggattt taatggtgct ttttctgcca ttcttcgacg ccccatctgt ggctatcacg
    51721 ctttaagact gttatggcgt ccgcaatagg aagaaaccaa gccagatggt taaagtcttc
    51781 caagggcttt gagatagctt ggaatgatgt cacctcgtac aggtaggcag gattatagta
    51841 gtaggtatcg cggtgacgag aatagaagta ttcgtctgct tgaccataat aataaccaat
    51901 atcagcagca aatcccagct cctcaactag ctcacgctcc agtgcctgta gctggctttc
    51961 accagcctct atttctcctc ctggcaaaaa ccaagcacca tttggagcct gcactaggat
    52021 aatctctgtt ttagccgagt taggaatcac tgcatagaca ccgtaacgtg cggtgtaatg
    52081 ctggtcatct atcttatcac caaatattgg aacggtcata tcgcttctcc tttgttttat
    52141 tatactaaat ttttggtcat tattctcata aaactgtaga tttatcaaaa atgtttcata
    52201 aaaaaatgct cgtcaaaaag agagaaaatg ctgtctgctt ttctctctgc ttttctctct
    52261 gctttttggt atgccctgtt agtccgcctg cttcgcctga gatttgacta caggcttgat
    52321 tataatgtgt ccattagagg tcaagacagc tcgcatgtct ttttctgctg ggtgctcaag
    52381 gtagaagtca gtaatggcgt cctcaatgta gtcctgaatg gtgcggcgca atggtcgtgc
    52441 tcccatctta ggatcatagc ctagctcaac gagcttttct ttgacctttt gggtgacatc
    52501 aaggcgaatg ttattgtgag caaggcggtg gttaacatca tcgagcatta aatgaacgat
    52561 atgtaaaaga ttgtccttgc ttagtggctg aaactcaata atgccatcaa agcgattcat
    52621 gaactcgggg ctaaagaaat gactgagctc tcctaaaaca gagtttgtcc gcccttctct
    52681 agcagcgcca aagcctactg aggcctctgt tttgccagtg ccagcatttg atgtcatgat
    52741 gataatagtg tccttaaagc taacggtacg tccttgtccg tcggttaatc gtccgtcatc
    52801 taggacctgt aaaaacatgt gcatgacatc agggtgagcc ttttcgatct catctaacaa
    52861 aatgagcgag taagggttgc ggcgcacctg ctctgttaac tgacctgcct cctcatagcc
    52921 gacgtagccg ggaggggcac cgacaagctt agccacagcg tgcttttcca tgtattcaga
    52981 catgtcaaag cgaatcatgt tatcagcaga gccaaaaagc tcaatggcta attgcttgga
    53041 aagctctgtt ttaccgacac cagttgggcc aacaaagagg aaggagccga taggacgatt
    53101 tggggctccc agtccaacac gattacgacg gatagctttt gcaattttat caacagcatc
    53161 gtcttgaccg ataacatgct ttttgagatc ggcggccaga ttgactagct gtgattgttc
    53221 cttttccttt aaatcaccaa ctggaatatt ggttttttgc tcaacgattg cttcgatggt
    53281 cttgtcagtg atgattggaa tatcctgctc atctagcttt tgagcctgca tttctttata
    53341 tttggcgatt tgatcgcgga aataggctgc tcgctcataa tcctcatcac gtgtggcttg
    53401 tgtcttgagg ttttcagcct caatcaaacg cttatcaatg tctttggggt caacaaagtt
    53461 aagggttagg ttcatctttg agccggcttc atctagcagg tcaatggcct tatcaggcaa
    53521 gaagcggtct tgaatatagc ggttggagag gttagcagct gcttcaatag ccgactggct
    53581 atatttgaca tggtgatagt cctcatattt gggttggatt ccttttagga tagtgattgt
    53641 ttcttcaacc gaaggctcgt ccaccttaac cggctgcatg cgtcgctcaa gggctgcgtc
    53701 cttttcgatg atgcgatatt cattgagagt ggtcgctccc actaattgaa gctcaccacg
    53761 agcaagtgct ggctttaaaa tatttcctgc gtccatgctg ccgtcaccaa ctgcaccagc
    53821 tcccacaatt tcatggattt catcaataaa tagaatcacg tcatggcgct tgcggatttc
    53881 ctccatgagc ttttgcatgc gctcttcaaa ttggccacga atacctgtcc cctgaacgag
    53941 gctaaccaca tcaaggcgaa tcacctgctt actctgtagc ttttgtggca catcgccatc
    54001 aacgattttt tgagcaaggc cttcaacgac agcagtctta ccaacacctg gttctccgat
    54061 taggacaggg ttatttttgg tacgacggtt gagaatctcg atcacgcgga taatctcatc
    54121 gtcacgtccg atgacaggat caatatcacc acgcttagcc atttcagtga tattaatgcc
    54181 gaattcctca agcaaacctt tgttagcctc ttgtgctggc tgtgtgtgat tgggacggta
    54241 gccattgtga cctccgccat tatggccgcc tgattgggta ggtggtgtat tgggcaattg
    54301 accgaaggct ctaaaattgt tcaggtcacc aaaaaagtca tcaaagaaag ggttttgaga
    54361 aggctgctgc gccttttggt tgccattata gcctcctaag ataggatttt tagggtctgt
    54421 tttcatgatt tggtagcaat tttgacagag gtcaatctgc ctttgctttc cgttaatgct
    54481 tgtataaaga tgaatggttg attcgtttaa attacagttt tgacaaagca tatcatacct
    54541 ccaaggggtt atctaaaaag tcaaggtcat ttagtcaaaa atggtcaaac tttatagtca
    54601 tattatagca ccttaggctt ggaaatcaag taaaaagctt cattattagc actttcaggt
    54661 atagagtgat aatctctata aatcttgctg ctcattggtt caaaaaagtc gtcaaagggg
    54721 ataaaataaa gagaaaatgg ctacttttct tgtttgtttt cgatgattta tgttaaaata
    54781 tatagggaca ataaacgaat aggagaaacg aaatggaatc acatttagtg agaatcatca
    54841 accgtctgga gctgatggta acagatggcg gtaatttaaa gagaaacttt gagcgagatg
    54901 gtgttgttgt tgcagaggtt gcatttgtca acgatcctga aaatggtcca gtctttattt
    54961 tacgtgatat tgaagcgcgt gagtcatatt catttgatag catcgatttg attgcgatgg
    55021 aaatttacga tttgttatat taagctattg atgatgacat gggcttgctg ggaggcaggt
    55081 cagacagagg acaagctggt gatttactgg tttgttttta ttatccctta aagcctcaag
    55141 acagctccag gaaaggcctt tctcctatgg tctttctagc cggtagggct tgatagtgat
    55201 taatagtgat ctgctctagc acggtcttga gcttttactg tcagaggctt gtgaccttag
    55261 ccactcgcag taaagggtac tggcccagta agcaaggtag gctaagtatc aatgtgaagt
    55321 tctaaccttg atcttagtga aatatttttg aggtgaatta agatgttaaa agtccttaga
    55381 atgctcattt ctaagggttt tgttgtgtct agctgttggt gtttgaaaga gcggtggtat
    55441 gataaagaga ggtcagaaaa gacctctctg atgtttgtga ttagctgtta gctattgcca
    55501 taggggaaag acacaatagc tagcttagct tttctttttc tttaggttta ggacgcctgc
    55561 gctagtgatg acgctaaggg ctgcaagggt gaagaatggg tgatttgtct cccctgtagc
    55621 tggtagcgtg ctcttttgag ctgctggtgc tgacttaggc gctggtgctt taggctgagc
    55681 tgatttttct ggagcctttg gtgcaggtgt cttttcaggt gcttttggag ctgatggttt
    55741 tgtatctttt ccttgatcac cctttggttt ttgctcgcct ttttcgccgc gttgtccttg
    55801 ctcgcctttt tcgccgcgtt gtccttgctc acctttttca ccgcgttgtc cttgctcacc
    55861 tttttcaccg cgttgtcctt gctcaccttt ttcaccgcgt tgtccttgct cacctttttc
    55921 accgcgttgt ccttgctcgc ctttttcacc gcgttgtcct tgctcacctt tttcaccgcg
    55981 ttgtccttgc tcaccttttt caccgcgttg tccttgctcg cctttttcgc cgcgttgtcc
    56041 ttgctcacct ttttcgccgc gttcgcctct gtcaccctta gggccggctg gtccttgttc
    56101 acctttagga cctgtttctc cggtttcgcc tttatctcca cgtggtccca taggcccaac
    56161 aggaccttgc tctccgcgtt cccctctagg tccggcaggc cccacaggtc cctgaggacc
    56221 acctttttta gcttgtagtt ctaagttttg taagtaggtt tgcatgaatt gtcttaatgt
    56281 atgtaggtat actcttactt cgccatctcc gagtccgtcc ctaattagtt cagctggatc
    56341 tggataggac tctaatcgcg tataatcttc agctcgggca tttccagctg ttcctaggct
    56401 ggccattgtt gctagggcaa tggctgctga gcagacgctg tacttgcgta ttgttttttt
    56461 catctttctc tcctttgatg atagtatcat tactttttca aaattctttc ccgaagaaga
    56521 gtttaacatg gtagcttgct atgagaaaca gctaggcgcc actttgtctc cgtagttttt
    56581 ttaattcaat gctgaatcgt ctgattttat cagagggtta ttgtttttaa aggcgaggag
    56641 ttgctttgct cagctagtct agcaagttca caggtcagct tatgtttctt atcaagcttg
    56701 tttgtttttg agaatatttt tcgataaaaa gatgttgtat taatattcat gttatagtat
    56761 aattatattc gttgccatga ctttatgaat gttaggagat aggaatggat tttacctttt
    56821 tacccaaata ctgggcttat ttcaattatg gtgtgcttgt aaccatgatg atttcagcct
    56881 gtgttgtctt ttttggcacg attataggtc ttttagtgac cctgataaaa cgcagtcata
    56941 tcaagccttt gtcttggctt gtcagtcttt atgtctggat ttttcgtgga acgccgatgg
    57001 tggtacagat catgattgct tttgcttggc tgcatttcaa cgatctgccc attgtaggct
    57061 ttggtgtgtt ggatttggat ttttcaagac tgcttcctgg tattattatt atttccttga
    57121 atagcggtgc ttacatatct gaaatcgtca gggctgggat tgaggcggtg ccaaaggggc
    57181 agctggaggc tgcttactct cttggtatcc gtcctaagaa cgccatgcgc tatgtgattt
    57241 tgcctcaggc ctttaagaat attttgccgg ccttgggcaa tgaattgatc accattatca
    57301 aggatagtgc cttgcttcag acgattggtg tgatggagct ttggaatgga gctcagtcgg
    57361 ttgtgacggc gacctatctg cctattacac ccttgctgtt tgcggccttt tattacttga
    57421 tgataacaac aatattgtcg caattattag gctgcttgga gcgcaagcta gcacagggag
    57481 ggagataaga tgactgagac agtgatttcg attcgtcagt tgcataagag ctttggcaag
    57541 catgaggtgc taaaaggaat agacctgacc attaatcagg gtgaggttgt ggtgattatt
    57601 gggccatctg gctcaggaaa gtccacgcta ttgcgcacga tgaatttgct tgaggtgcca
    57661 acaaagggac acatcagctt tgagggcgtc gatattacgg ataaggcaaa tgatattttc
    57721 aagatgcgtg agaagatggg catggttttt cagcagttta atctgtttcc caatatgaca
    57781 gtgctggaaa acatcaccct gtcacccatc aaaacaaaag gaatgtcaag ggctggcgcg
    57841 gagcagagag cttatgagct gcttgagcga gttgggctga gagataaggc tgctgcctat
    57901 ccggcaagct tatccggtgg tcagcagcag cgcattgcga ttgcgcgcgg cttggcaatg
    57961 gatcccgatg tgctgctctt tgatgagccg acctcagcgc ttgaccctga gatggtgggt
    58021 gaggttttgg ctgttatgca ggatttggca aaatcaggca tgacgatggt tattgtaacg
    58081 catgaaatgg gctttgccaa agaggtggcg gatcgcgtga tttttatgga cggtggtctt
    58141 gtgattgaag agggcagtcc agttcaggta tttgaagctc ctaaggagga gcggaccaag
    58201 gactttttga gcaaggtatt gtcatagctg gcgcagctaa agggcagcat gtcacctcaa
    58261 ggtctggcta ttagtcaatt ggctgtttgt tttgggcatt ttgtttgtaa aaggcttaga
    58321 aagtctggtt ggtgctgtag ccatatctgg ctttgctacg cttgggctgc tagctggtca
    58381 gtgggtatca tagtgattgg aggtgtggtc tctttattgg tcaacattgc tgtggcaggc
    58441 tagcacaggg gctttgcttg ttgtgctggg taaggggttt catttgcatg actgttaaca
    58501 ttgcttaatt gatgaattag gttgactttt gttttattgt ttgatactat tcaggtaagt
    58561 ctgtcattag aaagcgcttt gcttttttga tgatggaaat catgatcata tgatcacgtc
    58621 ttaggtaata tgttgttgtc aacatggtgg tctgaaagta ggaggataat atggactaca
    58681 aagctgttta tcaggagtgg ctgcacaatg attttttcaa tgaagaaatc aaggcagatt
    58741 tagaggcgat taagcatgat gaggctgaga ttcaagaccg tttttataag gtgcttgagt
    58801 ttgggacagc aggacttaga ggaaagctcg gtgctgggac caaccgtatg aatatttaca
    58861 tggttggtaa ggctgcgcag gctttagcta ataccattat tgatcatggg ccagaggcag
    58921 tctcacgcgg gattgccatc agctatgatg tgcgctataa gtctaaggaa ttcgcagaat
    58981 tgacctgctc gatcatggca gccaatggga tcaagtctta tatctacaag gggattcgtc
    59041 cgacaccgat gtgctcttat gcgattcgtg ccttgaactg tatctctggt gtcatgatta
    59101 ctgctagtca caatcctcag gcctacaatg gctacaaggc ttattgggaa gaggggtcac
    59161 agatcctaga tgacattgct aatcagatag cggttcatat ggacgctatt gagcgctttg
    59221 aggacgttaa gcagataccc tttgaggagg cattggcaag tggtctgacc agctatattg
    59281 atgatagtat agaggaggcc tataagaaag aggttttagg cttgaccatc aatgatactg
    59341 atattgataa gtcagtgcgt gtggtttata cacctttgaa tggcgttggt aatttgcctg
    59401 ttcgtgaggt attgaagaga cgaggctttg atcatgtctt tgtagtgccg gagcaggaaa
    59461 tgccagaccc agatttcaca acagttggtt atccaaatcc agaggtacca aaggcctttg
    59521 cttattcaga aagactaggg caagaagtag gagcagctat tctgattgcg actgatccgg
    59581 actgtgatcg tgtggcacta gaggttcgag ctgctgacgg tagttatgtc tttcttaatg
    59641 gtaataagat tggtgctttg ttgtcctact atatcttttc acagcgtcat gctaggcata
    59701 atcttcctga caatcctgtc cttgtcaaat caattgtaac aggggattta tcaaaagcta
    59761 ttgccgctaa atatgacgtt gaaacggttg agactcttac aggctttaaa aacatctgtg
    59821 gtaaggctaa tgactatgac atcacaaagg agaagaccta cgtctttggc tatgaggaaa
    59881 gcattggttt ttgttacggt acctttgtgc gtgataagga cgcggttagc gcctcaatga
    59941 tggtggtaga aatggctgcc tactacaagc aaaggggtca gtcactctta gatgtgcttc
    60001 aagacattta caaggaattt ggctattaca atgagcgtca ggtagcgcta gagctagagg
    60061 gtgttgaggg gcagaagcgt attgcacgta tcatggagga ctttagaaat gagcctattg
    60121 agcatgcagg tgctatgagc ttgaagacca ttgtagactt taaggacggc taccttgatt
    60181 ttccaaagca aaattgtttg aaatattatt ttgatgatgg gtcatggtat gcgctgagac
    60241 catctggaac agagcctaag atcaagcttt acatctatac tattggtgaa acagaggcag
    60301 acagcattgc taagctagac gctattgagt cagcttgtca agcaaagatg gacagtgtca
    60361 gctaattgtt caagctctgc aacagaaaat cagctaatca ataagcaaaa aggaaaagga
    60421 agtgacagtg cttccttttt tcgttataat agttaaaaaa ttagcaagga gtgcatatgg
    60481 tacagattat tgatgggaag gccctagcac agaaaatgca ggcagcattg gctaagaagg
    60541 tagagagctt aaaggcagaa aaaggaattg ttccaggcct tgttgtcatt ctggtaggag
    60601 acaaccctgc tagtcaggtt tacgtccgta ataaggaacg cgctgcctta gcagcaggct
    60661 ttaaaagtga aaccgttcgc ttgtctgatt cagtctgtca ggaagagttg atagagctca
    60721 ttgagcaata taatcaagat gatacgattc atggtatttt agtgcagctt cctcttccgc
    60781 accatattaa tgacaaaagc attatccttg ctattgatcc taaaaaggac gtcgatggct
    60841 ttcaccctat gaatacaggt catctgtggt caggtcgtcc gaatatggtc ccttgtactc
    60901 cggcagggat tatggagatg tttcatgact atggtatcga acttgaaggg aaaaatgctg
    60961 ttattgtcgg gcgctcaaat attgttggga agcctatggc gcagctactg ttggataaaa
    61021 atgctacggt aacgcttacc cattcgcgca cgcgccgact ggcagatatt tgtcgtcgtg
    61081 ctgatatctt gattgttgct attggtcagg ggcattttat cacaaaggag tttgttaaag
    61141 agggtgctgt tgttatagat gttggtatga atcgtgacgt caatgggcga ttgattggag
    61201 acgtcgcctt tgatgaggtg tcagagctgg ctagcatgat tactcctgtt ccgggtggtg
    61261 ttggaccgat gaccattact atgcttttgg agcaaaccta tcaagcagct ctaagaaggg
    61321 tgagtcaatg attatagatc aatcgtttgt tgctagggtt gttgttccgc ggcaggctga
    61381 ctcccataag gggagttacg gcagagtact gttagtaggt ggcttgtatc catacggtgg
    61441 tgctattatt atggtagcgc tggcctgtgt tcatagtggt gctggcctag taactgttgc
    61501 aactgataga gaaactattg ctgccttgca tagtcatttg ccagaggcga tggctattgc
    61561 ggtagatgat gaggaattac tgttatctca gctaggtatg gcagacctga ttttgattgg
    61621 tccggggctg tcggagaata gcagagcagc taggctgttt gaattggtcc ttgcacatgt
    61681 cgctgatcat caggtattgg tcattgatgg ctctgcctta aggcttttag cgaaaagggc
    61741 agctgatgtt aagcagctga ggtgccctct tgtgttaacg ccacaccaaa aggaatggga
    61801 ggcgctgtca ggtttagcga ttgatcagca gtatgatgct gccaaccaag cagctctcaa
    61861 gcattttcca agggctacga ttttggttgc taaaagctca gcaaccaaga tttatcatgg
    61921 caaccagatc taccggctaa gagtgggcgg accttatcag gctacaggtg gtatggggga
    61981 taccttggca ggtatgatag cagggatagc tgtccagttt ccagagtcaa gcttggtggc
    62041 taaggttgct tgtgcgacct atctgcactc tgcgattgct gatgagctgg caaagactgc
    62101 ctatgtggtt ttgccgactg ctattagcta tgagcttcct agatggctaa aggcaatcag
    62161 cacaggccag aagctaggtt gaggctgtgc tgcgaggtcg tttgggaaaa gcggttaatt
    62221 ggtaggcatg acagcagctg gtttcagtcg tttagctatt ttgagtttag agctgctagc
    62281 ttaagactgg gtgctgcttt atgattcaag gaagctatca ttggaaaaac ttgtgtcaag
    62341 ctgtagaagc cctagctggc ttcttttttt gtctcttttt tgctcactat ttatgtggaa
    62401 acatgatata attgcattag tatacagttg gagcagttag gcttcatgaa gtgaaaggta
    62461 aactgatggc agactattta tccgtcactc agctgacaaa atatttaaaa ttgaaatttg
    62521 atcgagaccc ttatctggag cgtgtctatc tcactggtca ggtatctaat ttcagaaaaa
    62581 gaccaaatca ccaatatttt tccttaaagg acgagggagc ggtgattcag gccaccatgt
    62641 gggcaggagc ttataaaaag cttggctttg atttagaaga gggcatgaag ctcaatgtgg
    62701 ttgggcgtat tcagctctat gagccaaatg gctcgtattc aatgatcatt gaaaaggctg
    62761 agccagacgg tattggtgct ttggcgctgc aatttgagca gctcaggcaa aagctggctg
    62821 gtgaaggctt ctttgatgag aggcataagc aggccctgcc gcaatttgtg acaaaggtag
    62881 gtattgtgac gagtccaagt ggggctgtga ttcgtgatat tatcacaacc atctcaaggc
    62941 gttttcctgg ggtgagtatt cttttgtttc caacaaaggt tcagggtgag ggggcagctc
    63001 aagaggttgc tgctaatatt actaaggcta accagcgtga ggatctggat ttgttgattg
    63061 ttggacgcgg cggtggctcg attgaggacc tgtgggcttt caatgaggaa atcgttgttc
    63121 aggctatttt tgagtctcgc ctgcctgtta tttccagcgt aggacatgag acagatacaa
    63181 ccttggctga ttttgtggct gatcgcagag ctgccacccc aaccgcagct gcagagctgg
    63241 cgacacctat tacaaaaaca gatattgtct cttggattgc tgagcagcag agccggtcct
    63301 atcaagcctg tctgcgctat atcagacaag ggcaggagcg ggtggataag ctttcttatt
    63361 ctgttatttt caggcagcca gagaggctct atgatgctta tagtcaacgc ttagataggc
    63421 ttacgacctc cttgatgacc acttttaaag agacattatc aggagctaag caggagcact
    63481 tgattttgga gcatcgttta gcctctgtca atgtacaggc aaggcttgag cgttatcagg
    63541 atcgtctggc aactgcgcat cgtctcttga tagccaatat gaccaatcaa tatgacagta
    63601 agctagcagg ctttgagcga gctcaagctg ccttgctgtc gcttgatacg agccgtatca
    63661 ttgcccgcgg ctatgccctg ttaaaaaagg acggtgtagt agctgcttgt gttaaggaca
    63721 ttaaaaaggg agatcatctt agtattatca tgcgtgatgg tcaattagaa gtagaggtag
    63781 aagatgtcaa cgaaaaaaat atttgaagag cgtttacaag aattagaggc cattgtgacg
    63841 aggctagaaa atggtgatgt gccactagaa gaggccatct ctgaatttca aaagggtatg
    63901 gtgctgtcca aggaccttca aaaaacctta caagcagctg aaaagacact tgttaaggtc
    63961 atgcaggcag atggcacaga gctagaaatg gatgcctaat ggataagcta acaagaatta
    64021 atgccacgat tcatcagtat tatgacaggc agtctactgt ttcagcagat ctggaggagg
    64081 ccattttata ttctgttgat ggtggaggaa agaggctccg tccactcatg ttattggagc
    64141 tgctagaggg ctttggtctt gccttgacag acgctcatta cgcggttgct gctgctgttg
    64201 agatgattca tacaggaagt ttgattcacg atgatttgcc tgctatggat aacgatgatt
    64261 accgtcgcgg gcgactaact agccacaagc aatttaatga agcaactgct attttggcag
    64321 gagatagtct ttttttggac ccttttgctc taatcgcagg ggcagatttg ccggctgacc
    64381 tgctggtgca attgattcag cagttttcct tagcgtcagg aacctttggc atggtcggtg
    64441 gtcagctctt ggacatgaag ggtgagcatc agctgctgga tattcaggag ctatctgata
    64501 ttcatgccaa taaaacaggg aaattgttga cccttccttt tgtggctgcg ggtatcatag
    64561 ctgagcagtc agcagacgtt ttgtcttgtc tgtgggaggc tggtaggctt gttggacagg
    64621 cctttcagat aagagatgat atattagacc ttacggctag ctttgctgat cttggcaaga
    64681 caccgcaaaa ggaccttgct gctgcaaaat caacctatcc gagtctgctt ggtttagagc
    64741 gctcaagggc tattttggag gagtctttga gtcaagcgct agctattttt agcagactag
    64801 aaagggaaga aggctttgag tctcaggcta ttatcaaaag gatcgagggg ttgcgactaa
    64861 atggctaaag aaagagtaga tgtgctagcc tatagacagg gactttttga aacgcgagaa
    64921 caggccaagc gcggtgtgat ggctgggcta gttatatcag ctataagtgg cttacgcttt
    64981 gataagcctg gtgaaaagat tgatgagggg atcgaactaa ggctcaaggg tgagaagctt
    65041 aagtatgtca gccgaggggg tctcaagctg gaaaaagcct tgcaggtctt tgggatctct
    65101 gtgcaggata aggtgacaat tgatattggt gcttcaacag gtggctttac agatgttatg
    65161 ctacaggcag gagctaggct ggtttacgct gttgatgttg gaaccaatca attggtctgg
    65221 aagctcaggc aggatagtcg tgttcgaagc atggagcagt acaattttcg ctatgcaaag
    65281 ctagcagatt tttcagaagg tcagccagcc tttgccagca ttgatgtgtc ctttatttct
    65341 cttagcctga tactgccgac attgcactgt attttgcagg aaggggcaga ggctgttgct
    65401 ctgatcaagc cacagtttga agcagggcgc gagcagattg gcaaaaaagg gattgtcaag
    65461 gatagactga ttcatgaaaa agtgattaag caggtggcag atactgctct taattgcgga
    65521 tttatcgtta aggggcttga tttttcgcct atccaaggtg gtcatggcaa tattgaattt
    65581 ttggctcatt tagtcaaggg aaagggctcc aaggctattg atgatcagct catacagagc
    65641 gttgttagca gtgcacataa ggaatttaaa cagcatgaaa aagagtgaac gattagattt
    65701 aataaaaaaa atggttttgt ctcatgagat tgagactcag catgagctat taaagctcct
    65761 agctgattat gggctagagc taactcaggc cactatttca agagacatga atgaaattgg
    65821 cattgtcaaa attccatctg gaactgggcg ttatgtctat ggcttgtcac aggatagtgg
    65881 caagcgggtg gtgcaaaggc ctgcctctat caaaaaaacg attttggaaa tgtctgaaaa
    65941 aacagcgggc ttggagcagc atattcacct caacgttgtt ccaggcaata gcaagctaat
    66001 caaacgttat ttgatgacag acttttcagg tcaattgttt agcctgattg cagatgatga
    66061 tagtttgctg ttgattgcaa aatcagaagc agacgctgat catatccgtc aggaattgtc
    66121 cctttggatg cagggattgg tctaaaaaat agagagaagc cgatgttatt agaaatttcc
    66181 attaagaatt ttgctatcat agaggaaatc tctttaaact ttgaaaacgg tatgaccgta
    66241 ctgactgggg agacaggggc aggaaagtcc attatcattg atgcgatgaa catgctgctg
    66301 ggtgcgcgcg caagcactga ggtgattcga catggtgctg ataaggcaga gattgagggc
    66361 ttcttttcgg ttgatgctaa tcctcattta gccgctgtgc tggcagaatc agggattagc
    66421 atggaagagg agttgattct tcgtcgtgat atttttgcta acggtcgtag cgtcagccgt
    66481 atcaatggtc aaatggtcac tgtcagcacc ctaaaaaaac ttgggcagtt tttagtggat
    66541 attcatggtc agcatgatca ggaggaattg atgcgtccac agctgcacca gcatattttg
    66601 gatagttttg gagatgaggc ctttgaccag ctcaagcagt cctatcagca gatttttgat
    66661 cgctataagg ctttgcgaag gcaggctctt gagaagcaaa aaaatgaaaa agaacatcag
    66721 gcgcgccttg acctgctggc ctttcagata ggggaaattg aggcagcaga tttggttaga
    66781 ggagaagatg acctgcttaa ccaagaaagg cagcgattgc tcaatcacaa aaagattgct
    66841 gataccttaa ccagtgccta cctttccttg gataatgagg acttttccag tctctcacag
    66901 gtccgctcta gcatgaatga gttgctgtct attgaggacc ttgccccaga gtatcagctt
    66961 atatcagctg gtgtgtcaga ggcttattat attcttgagg aggtcacaaa gcaattatct
    67021 gataccatcg accagcttga ttttgatgca ggcagattgc aggacattga gctgcgttta
    67081 gacagcatta atagtctgac aagaaaatat ggcggtggtg tgaatgatgt tttggactac
    67141 tatgccaata ttaccaagga ataccagtta ttaagcggag atgaccgttc ctctgatgag
    67201 ctagaaaggg aattaaaggt ccttgagaag caactggtga tgactgcctc acagctaagt
    67261 gacaagcgtc atgccctggc tctagagcta gaagccgaca tcaaagctga gctgagagag
    67321 ctttatatgg aaaaggcgga ctttaaggtc cactttacaa ggtcaaagtt taatcgagaa
    67381 ggcaatgaaa gcttagaatt ttatatctca accaatccag gtgagggctt taagccgctg
    67441 gttaaggttg cttcaggtgg tgagctttcc cgcttgatgc ttgctatcaa ggctgccatt
    67501 tctaaaaaag aggacaagac gagtattgtc tttgacgagg tggatactgg agtttcagga
    67561 cgtgtggccc aggccattgc taaaaaaata tataaaattg gcagctatgg tcaggtatta
    67621 gcgatttcgc atttgccaca ggtggttgct attgcagata accagtattt tatttccaag
    67681 gaaagcaagg aggagtcgac agtgtctaag gctaagctgt tgacacagga ggagcggatc
    67741 gaggagattg cgaagatgat tgcaggagct gatgtcacag agacagcaag aaatcaagcg
    67801 cgtgaattgc taggtaagga ctgagtatca tagcaaaagc agaacagtag ctttagagca
    67861 agcttgcctg ctgcacttgt cgctacatgt tcagaatgag ccacctgaaa ggcaagcaag
    67921 aaggctagct cttatgcgta tgctatcaga agctaagtct ttttgtctct tgcattggcg
    67981 agtgattgat tgataatatt atgataaata gaaggactaa aagaatactg actgaggagg
    68041 taaaatgctg aaaaaaagaa tgggcttggc tagtctgcta gtgttgatga cctttgtgta
    68101 tcagtgctgt tcagttactg ctgagcagta ttccgatact gaggttgagg tgctgcagat
    68161 tagcgaggag aaaagccaga tcatggaaaa tcaagaggcg cttaaagacc tcaccacgtc
    68221 gtctgatcag ctaaagaagg aagctttaaa gcctaaagag gcagctacca acaagagcaa
    68281 gcaagaggct tcgacagttt atttagctga ggacgatcct gtaaccattg atagctctga
    68341 cgaggaaagc aatcaagata tcatagcgga ttctgttcct gatttggtta ttaaaggtga
    68401 tcaggtggat gtatctgagg ttatggtctc tgtaaaggag gattcatcga aagttgctaa
    68461 gcaaagaact gacgcagcgc agcggtacag tatagccaag catcaattga cccaaaagct
    68521 tgaggccttt aatgcggcaa cggaccaatt gctgaccatg attgctaaaa aatctgattt
    68581 gactggtcag tattatgtgg ttgggcattc gttgggagaa atgctggctg ctcaaaatga
    68641 gaaaaagctt gctgagcaat tagtcatgca acaaaagcac aaaaaaggct taggctcatc
    68701 agtcactatt ttagacgaat taggacgtgt gatttctgac attagtggtc ataaaggcat
    68761 gcttcctttt aatcgtaaga tcagctttaa ggtacatcaa gtcagatacg atcttccact
    68821 aactggtgat cgaacagtgc tacctgccca gctggctggc ttactgcttt tactaatagg
    68881 tcttatgctg cctaaagtag ctaacaagaa aagctaagat atggtcttgg cttttttatc
    68941 ttttaagagg gtgagttttt gacagatgtt ttagctaaca ccaagagcta gataccagct
    69001 ttgctttatt tttaaaggag tgataaaata aagagacgat aaatgaggtt agaaatggaa
    69061 cttaagatgg gaactattaa aattgttgca gattcatcaa tgacgattga accagagcta
    69121 atcaaatctc ttgatattac ggttgtaccg ctttctgtca tgattgatag caagctgtat
    69181 tctgataatg agctaaaaga ggaagggcaa tttctacagc tgatgagagc tagtaagtca
    69241 ttgccaaaaa ctagtcagcc accggtaggg ctttttgcag atatttatga gcgattggtc
    69301 aaggaggggg cgacagctat tgttgccatt cacctctcac cagctctttc aggaacaatt
    69361 gaggcatcac gtcagggagc tgaaattgca gcagcaccag ttacggtatt ggactcaggc
    69421 tttacagatc aggctttgaa gtttcaggtg gttgaagcgg ctagactggc tcaagctggc
    69481 gctagccttg aggaaatcct tgaggcggta gaggatatta aacgaaagac agagctttat
    69541 ataggggtat cagcacttga gcacttggtt aaggggggac gaatcggtcg tgtgacaggc
    69601 ttgcttagct ccttgctgaa tattcgtgtg gtcatggaaa tgaaaaatga taccctgcaa
    69661 acacttgtta aaggacgcgg caataagacc tttactaaat ggctggatag ctatctagca
    69721 gaaaatagcc agcgacagat agctgaggtg gccatttcct atgctggtca gagggatttt
    69781 gctgatagcc tgaagaagac aatcgctacg gtctttgatg ggccaattac tgttttggag
    69841 actggctcaa tcattcaaac acatactggc gagggcgctt ttgcggtgat ggttagatat
    69901 gaataagcga gggtttttgg gaggccttat cttctttttc agtgtttttg ccttatcatt
    69961 tgtgatatta gctgtcctta ttccaaagtc tgacccacag ctgaagaaaa gtgattttct
    70021 aaaaaataag aagataagcc tcaattatat tgctattgga gactccttga cagagggagt
    70081 gggtgatctc accaaccaag gaggctttgt gcccttattg tctggtgatc ttggagacta
    70141 ctttaatgct accgttaata ctgaaaatta cggtgtttcc ggtaatacca gccagcaaat
    70201 tttaacgaga atgactgaga acaaggagat cacagagcag ctcaaaaaag ctaatctcat
    70261 gacattaacg gttggtggca atgatgtctt ggctgttatt cgcaagaact tagctaatct
    70321 taaggtatca agctttaaaa agccagcaag gcaataccaa gagcgcttac gcaaaatcct
    70381 tgatttggcc agaaaggata atcaggatct gccgatcttt gttttaggta tctacaatcc
    70441 tttttatttg aattttcagg agctaacaga aatgcagacg gtcattaatg actggaacaa
    70501 aaaaacacaa gaggttgttg atgactatga ccatgtttac tttgttccaa ttaatgatct
    70561 attgtacaaa ggagtagatg gtaaagaggg cattgtccag tcaacaggag agcaaacaac
    70621 gattgtgaat gatgctttgt tttcagggga tcattttcac cccaataaca caggctacca
    70681 aatcatgtca gacgcagtaa tggagacaat aagaaagaat ggaaaagaaa ttaaacctta
    70741 attggtggaa atgggctttt ttgctattat tggcttttaa tgcagccttt ttagcagtta
    70801 ttggaagtcg tattatacaa ataagagagc ctaagtctga gctgatcaat caaaaagcag
    70861 caaagaatat taaaataggg accttaacaa ccactaaaga gcaattaaat gaggcagtcg
    70921 ttagctacct aaaggatttt cagacggaaa aaatgaccta taaggtgtat gccacctcct
    70981 cgaccattct ctttgaagga acctatcagc tcttaggata tgaggtgccg ttatacattt
    71041 attttcagcc tcatcgctta accaatggtg cgatacagct gcaggttctc tccttttctg
    71101 tggggaccct ttctttgccg gaaaaggacg ttttgcaata cttgaaatcc agctataagc
    71161 tgccaaaatt cgttgaagtc ttacctaagc aatcggctat tattatcaat ctacagcaat
    71221 tggaaaatga tgccaacatc tatttaaagg ctcaaaagat tgatcttgtc aaggatgata
    71281 ttcgatttga catctataag aaatgagtct aactaacgtt taatacttga cctgtggctg
    71341 ttttttagat atgataatat ctgttaaagc gttaagctta ctaattattt ggaggattgt
    71401 taaatggcta acaaacaaga tttaatcgca aaggttgcag aagcaactga gcttacaaag
    71461 aaagattcag cagcagcagt tgacgctgtc ttttctgcaa tcgaagcttt tcttgctgaa
    71521 ggtgaaaagg tacaattaat tggttttggt aactttgagg ttcgtgaacg cgctgctcgt
    71581 aaaggtcgca acccacaaac tggtgaagaa attgaaattg cagcttcaaa ggttccagca
    71641 ttcaaggctg gtaaagctct taaggacgct gtaaaataat aaatcaaaaa aagccctatc
    71701 tcattaagct gtttagcctg tgagataggg ctttttccat taaggaagga gtcttgtttc
    71761 aataagtaat cttgtgtgat cgtctgaaag attagcgcca ataatttcta atgtgcactg
    71821 tcttgggaac aagagttcca tttcataagg ataaaatgag tagggctgta caaaagcagc
    71881 ctggctgcct tgagggacct gaattcttaa ttccactgag cgatgtggca tagcagcatt
    71941 tttgatggct gtagtactca taaagccttg ctttgtataa tgagtgcctg gcttgatcgc
    72001 tgataggatc tgcggatcaa aggtcttatc atggtagtaa cgagcgagtt cctcttcaga
    72061 agtgcccaat tctgttaaga atgtttcata aacatagcga tagacgatga tattccaagg
    72121 gatggttagc ttatgagtag cactatcaag taaggctaca gactgctgca gctgggcatc
    72181 caactggctg gtatctccca tcacctgttc tagggctagg ttaatagggc tggcagaggc
    72241 gtatgtatac tgatacatca tctttttttc tgcttctgta aaggctgttt gagacctcca
    72301 gcgattggtg ataatgtatt tggtaacatc aggctcacta aatttataat aaggcttaaa
    72361 gctattccca tagggctcaa aaacaactgt ttgtccttca tcataagact gtgccttgat
    72421 ggttgaaggc tgaacgacaa gcaacgataa gaaaaatgta aacaagcata gtgtacgaat
    72481 agctatcctt tgataagata actttgcgtt atgatgttga tgagtcattt agcttttcct
    72541 cctttacagt agtgccaaga gtgtcatcac ctaatgatga tgtctgttgc taacaggatt
    72601 agccttagtt gaaatgatta caaacttcct taatgtaaca aacataataa aaataaatta
    72661 tttttttatt atatattagt taagctcaga tgacaagcta tttgattttt ttctgagata
    72721 atgttacaag ggatttctaa caccaatgac taactcagat gaagggcttt ttcttggagg
    72781 attgcctata gttacaatag taggcaagac tggcagtcgc catgatacct attccaataa
    72841 cagcaaaggt tgctagatga acagaggctg gtatacaggt catgatggta gttgccagtg
    72901 gcattaagag aatagcagtt gtgacgattg agctaaagac tcgtcctagc aatgcctcag
    72961 gaactttttt ttgaacgata gaaaagaagt gaatgttaaa gattgttaaa aagcattcaa
    73021 accataaatt cccaagggca atcacaatga ctggaagctt caagagagcc atagctgtta
    73081 ttagaagcat ccctaggcca ctaaggccta gggataggag taagctttgc tgattatttt
    73141 taaagagctt gttagccata aaagctccta agatagcccc taaagctccc atcgaaagaa
    73201 gactagcata gcttgattgg ctgcctagca gctgattcga aaaaggaatt aaataattga
    73261 aagcagcaat aaagaaattc acaagagaag caataatcaa caaagaaaaa atgtcattgt
    73321 catggtagat gaattgcagc ccctccttaa tatctgttaa aagctgaagc ctattgcctt
    73381 ggctgctctg tttagtgatg tgcctttctt tgtccttgat tgtatataga catagaaagg
    73441 acaatagaaa gctaatgcta tctagagcca aggctgtttt gatgccaaag caatccatca
    73501 ctaaaaaagc aagcattggt gaggaaatac tgatgatttg agatacgatt tctagctgag
    73561 cattgaaatg aacaagtctt tctgtttcaa ctagtgtgac cacataggct cgaaaagcag
    73621 ttccagagaa ggcatacgat attgctaaaa gagcattaac agtgataagc ccataaagca
    73681 tgatagtagg gttagctatc agggctaaaa gtccgcagct gatagctccg atagcatctg
    73741 tccacaataa caattgtcgt cgtttataac gatcagcaat ggcgccaccg ataggattta
    73801 agatgagtga aataaggcct tcagctagct gataataacc caaatattgt cggccagttg
    73861 ctccgagtcc agcaatcccg ctgctgttgc tgtagtcgta aacagtattg cctattttgt
    73921 taatagctcg acttgcgagc agctggtagt cgtttttgcg catgataaaa cctccaaaag
    73981 attatgtggt tttattataa atcagttttt tagggtctta tgtttttttg caaataaggc
    74041 tagaggaggc tacaaatctt tcaaaatcct tttggtaatt gtgcgctagg tgaggacaat
    74101 ccaggctctc aaaaatggaa atagcagtag tcatatcctt aatgccagac aaacactgtc
    74161 ctctttggta gtcctctaag ccctttaaaa ataaaaagat ggttttttca tatagcttgg
    74221 tttcattatt gagtagggct agtatctgct tttgataata gcgcgcatag tcaagctgat
    74281 gtcggtggat acaggtttcc caaatattga gaagggtgat ggtaaccaaa tgcttattgg
    74341 ttgaaatgct ttcgtagtag gtatgattgt ttagaatttc ctttcccatt ttatctaata
    74401 agggaatatc aataaaaaga tagagatttc caattaaaat cagctcatag atatgccagc
    74461 tttcagtcct aaaaaggtag tcagtgacct catcaagata agccttagga aaaggaatgc
    74521 taggattgca tttacagata aagccttgga gtagaatgct gtttaaatag taacgattgg
    74581 tatcaggatc agcttggtgc tttgccaatt cctgcttttg cagctgcttg aatccctcaa
    74641 tatcgcgtgc atattccagc ttgatcagct gcgacatgaa ttgaatttgc tctgtctgtt
    74701 tgaagttggc agctatgtcc ataaattcgc tgatttccac ttgcatgctg tctaaagctg
    74761 ttaaaaactt tgttactgat agatcagatt cgccgcgttc aaagcgggat aactgagaca
    74821 aggacacgtc tttactggca agctgctgta aggtgatatt tctgttttgt ctaatgctgc
    74881 gaaatgcttt tcccaactga tgattagtca tattttttcc tcctctaatg agtatatcat
    74941 gtaaggcttc tgttgctgta ttttcccgta tgtgcaaacc ttgaaacttg tctgctgccg
    75001 ccacaaaggc atgaaaacat ttacactttt tgatagctat ttttatcatt gatgtagtct
    75061 ttttcgcaac atttgtacgg gatcatcaga ttaaaattaa gaaactgatg atgtgacact
    75121 gtaaacatgc taaaaatatg ttgaacaatg cctgtagctg gaaaatgggt acatgtattt
    75181 tcttcatgcc tgcgtcgtga cctgctgcta ttaaagcttg cttgaaaggg aaaaagagct
    75241 tataatagca gtgagaacat taaaaatgaa agtagagata tgccaataat tgttatcctt
    75301 ggacttgcta tcttttcggt ggttaaggtc attatttttc tatgctttta taaagcattt
    75361 gagaaaaaac aactaaagaa gctagaacag gatcaaaaag aaaccaagca ggcgattgac
    75421 caagaggagt caaaaaaagc ctttcccttt taacataaag ctagaaaaag tctgagacct
    75481 ttcgtctcag acttttttta aggcttatat tgtaattgac cacgaaaatc gtctagtgtc
    75541 tggtagccct tttcagccat aatgtcttgt agctccttag tgatacgctt aaaaatagct
    75601 ggaccttcct ggtgcagtgc tgttccaatt tgtaccatag ctgcgccgca taggatatgc
    75661 tcaaaggcat cacgtcctgt tttgacaccg cctgtgccaa tgatctgaat agaagagtta
    75721 agccgttggt aaaaggcatg aacattagcc agggcagttg gcttgatgta atcaccacca
    75781 ataccaccaa agccgttttt aggcttgatg acgacctgct catcatcaat aaccaagcca
    75841 ttgccaatgg aattaacaca gttggcaaag gctaaggggt attgattgaa aatggctgcg
    75901 gcttggtcaa aatggacaat atcaaaataa ggaggtagct tgatgcctag aggcttggtg
    75961 taataggaaa agatcttttt taggagctga tctgtggctt caaagtcata ggccagctga
    76021 ggcttacctg ggacattagg gcacgacagg tttagctcga caagtccttg ataatcagag
    76081 gcctgaatag cttttaggat agtctcggtt tcttcagcag acatgcccac aacagataaa
    76141 aagtggtgct tgcttgcttg atccttttgc atttctgtga caatatctaa ataatactgg
    76201 tagccatgat taggaagtcc cattgaattg attgagccaa gtgctgtatc tgcatagcga
    76261 ggctcagggt tgccctgtcg aggggctaga gtacctgttt ttgtcacaaa ggacccagcc
    76321 tcagaggcct caatggctag cagctcttcc ttggtcatgc aatacactcc agcagcgttc
    76381 atcaggcaat tattaaaggc aaatgtagcg atttttgtgg cagtagaaac catgttttcc
    76441 tccattttta gacaaatttt ttctattcta tcactagggc atgagaatag caaggcattt
    76501 ttgcaaaata cttgcttgaa ggctttcttt tgtgaggttt tagcgttttt catgatatta
    76561 acaaaatgat tttcaataaa gagaggaata gactagcttt tttgacctat tttttgtaaa
    76621 ataggagttg taaaaaggca agaagccttt aaacttaata aggagatatt aactaatggt
    76681 aaaattggtt ttcgctcgtc atggtgagtc agaatggaac aaagcaaacc ttttcactgg
    76741 ttgggctgac gttgatttgt ccgaaaaggg aacacagcag gctattgatg ctggaaaatt
    76801 gatcaaggaa gctggtattg catttgatct tgcctttaca tctgtgctta agcgtgctat
    76861 caagacaact aatcttgcac ttgagtattc tgatcagctt tgggtacctg ttgaaaaatc
    76921 atggcgcttg aacgagcgtc actatggtgg cttgactggt aaaaacaagg cagaagcagc
    76981 tgagcaattt ggtgatgagc aggttcatat ctggcgccgt tcatacgatg tgttgcctcc
    77041 tgatatggct aaagatgatg agcattcagc acatactgat cgtcgttacg ctcatcttga
    77101 tcattctgtt attccagatg cagaaaacct gaaggtaaca ctagagcgtg cccttccttt
    77161 ctgggaagat aagattgcac cagccttagt tgatggtaaa aatgtttttg ttggagcaca
    77221 tggtaactct attcgtgccc ttgtcaaaca catcaagcaa ttatcagatg acgagattat
    77281 gaatgtggaa atcccgaact tcccaccgct tgtgtttgaa tttgatgaca agctaaatct
    77341 tactgctgag tactacctcg gtggtgaata atgctgtgag gccagaccta gctctggctt
    77401 tttttgttat gtgataaaaa aggcgtttcc aacagaaatg tgatatgata gttaaaaagt
    77461 ggtaaaagaa gggaatctta tgaaagtaaa ggaacgccga gaagctatta cagataggtt
    77521 aagccaagca caagaagcca tctcagcaac tagcttagcc aaggcattgg gagttagtcg
    77581 tcaggtgatt gtcggagaca ttgccttact tagggcgcag cagcttgaca ttatttcaac
    77641 accaaaggga tatatcctgt caaatgcttt gtttagtcat cactattctg ctagaattgt
    77701 ttgccagcat ggacctgagc agacaaggca ggagttggag ttgatattag cacatgatgg
    77761 cattgtgacc aatgtggagg tagagcaccc tatttatggc atgctgacag caccgcttaa
    77821 cattaaaagc tcagctgata tcaataactt tattgaaaag ctcggagcct ctaaggcaga
    77881 attattgtcg tctttgacag agggtctgca cactcacctt ttgtcctgcc ctgatcagga
    77941 ggcatttgaa gagatcaaga gagatctagc agctgcaggc attctctatg gtgaacaata
    78001 atctgatagc agctggcttc acagggattt agtcttggct tgatagccaa tgtccctctt
    78061 ttgtcgtagg tgatagggac cgcaggacag ctcctagatg ctgaggccaa agtcttgtgg
    78121 ctgggcctca aatgaggtta aaagggaagg aagctgctat ggttatggtg aaagggctag
    78181 atttaccctt acttttttgc taggataatc ttttatgctg ttaggccgca gggcttggtg
    78241 ctgcaatggc tgagatgtgt ctgtcttttg tcttagcttt tggtgcttga gaagggctgg
    78301 gattgagctt atgctgtggt tgttttttga tttgctaggt gtcttgacat ctgtcgcgtt
    78361 tttggttata ctaacgacta gtaaaaggag atattatgac caaaaaacca acacaactga
    78421 ttgcctactc ttctattttg gtggcctttg ccatcttgat tccgatgata atgcccatta
    78481 agcttattat tggcccggct tcctttaccc tagctagtca tctgcccttg tttttagcca
    78541 tatttatatc cattccggta gcgatcttgg tggggatagg aacaggtctg ggctttttgc
    78601 tagcaggatt tcctatgatt attgttatgc gagccttctc acacgtgctt tttgcagcta
    78661 ttgcggcttt tatgctcaaa aggcagccta aatggctgga aacaccgtta agaacctttg
    78721 tttttgggat tatagcaaat gtgattcatg gcctagcaga gtttttagtg gtttatctga
    78781 tgacagcaac agcagcaact gatctttctt atttttggtc aatgctaatg cttgttggct
    78841 ttgggtcttt gctgcatggt atggtggatt tttatctagc cttatttatc tggcgcttct
    78901 taaggcagaa gggtcatcta tcagtgacaa gctaggattt ctgtgagtat ttatgtttta
    78961 gtagccaagg ctgttacagg ctgaggctct tttttctgaa agcgcttgca tttttttgaa
    79021 aaaatgctat actaaagagt gcgtttgtaa atatactaac aaaaggagat gtcatgaaaa
    79081 caccagaaca gatattagcc gcgacgatta cgattggtga gcataaggtt gcaaagcctt
    79141 ttttggctaa ggctatttta ggctttattg gcggtgcgat gattagtttg ggctacttat
    79201 tgtatgttag gattgcagct agtgggctgg agacctttgg cgctttttct agtattttgg
    79261 gtgcttgtgc ctttccgatt gggctgatca ttattttgat ggctggcggt gaattgatca
    79321 caggcaacat gatggcggtg tcggcagcct tttttgcaaa aaagattaag gccaaggact
    79381 tgatggccaa ttggctggtg attacccttt ttaatatttt gggagccttg ttcgttgcct
    79441 ttgtttttgg tcattttctg ggtctgacag ctactggcag ctttaaagaa gaggtcattg
    79501 aggtggccca tgccaagctt gctgcaactc ctctacaggc tattgtttca ggaattggct
    79561 gtaactggtt tgttggcctg gcgctttggc tgtgctatgg cgctagtgat gcgacaggta
    79621 agctccttgg aacctggttt cctgtgatga cctttgttgc ccttggtttt cagcatagtg
    79681 tggccaatgc ctttgttatt ccggcggcta tttttgaggg tggcgccagc tggatcgatt
    79741 ttgcgactaa ttttgctctc gtttatgtgg gcaatgtcct tggcggtgct atctttgtta
    79801 gtctctttta ttacaaggct tatgatcact ctaaggaagc ctgattagtg ctgttatatt
    79861 tttagactgg gagaccttat tctcagtctt atttttatat tttgtgataa aataggaaac
    79921 gacgtttaaa aaggaggagt tgataagcat ctaatatggc atcatggata aaaaagaaaa
    79981 aagcaagcat tcctaggcga attcatctcc tttttttggt gattgttttt ttgtttgttg
    80041 ccctgatttt gagattggca caaatgcaga tttatgagaa ggatttttac aaggcaaagc
    80101 tgacagcgtc aaccgtttac aaagtaaaaa gctctatgcc aaggggaacc atttttgacc
    80161 gtaatgggaa ggttctagtt tctaatcgta tcaaggacgt ggtaacctat acgagaagtc
    80221 ccaaggctag tgctaaggac attaaggctt tggctcatca gctagctgct tatattagct
    80281 atcctgaggc taaagtgaca gtcagagcca aaaaggatta ttatttggca gatccagagg
    80341 cttatgctaa gacggttcaa gccttacccc aaaaggacaa ggtggatcgc tttggtaata
    80401 aattagtcga agcacagata tatcaaaatg cggcagcctc tcttaaggaa acagacttga
    80461 cctattcaga ccaagagcta aaggttattg ctatttttaa ccaaatgaat gcagcagctg
    80521 tttttagcac tgtaaagctc aaaacatcag ccttatctga gcaggatatt gccatcatta
    80581 tggccaataa gtcaaaatta ccaggtattt cagttgggac agactgggag cgtcaggtgg
    80641 aggagacaag ccttgctgct attattggaa gggtctctag tgaggaagcc ggtcttccaa
    80701 aggaagaagc aaaggcttat cttaaaaagg gctattcgct taatgatcgt gttggaacct
    80761 cttatctgga aaagcaatac gaggaggtcc ttcaaggaaa gcatgaaatc agagaaatca
    80821 aaacgagcag atctggtgag gttatttcag ataaaatagt cgaaaagggt cagatggggc
    80881 ggaacctgaa gttgagcgtg ccacttgatt ttcaacaggg cgttgagcag atcttgaatc
    80941 agcacttcca gacagagctc aaaaatggtc aggctgctta ctcagaaggg atctatgctg
    81001 tggcgcttaa ccctaatacg ggagcgattt tagcgatggc aggtctatca cacaatccca
    81061 aaaccggtga gcttcaaaag gacgctttag ggactattac tgatgtgttt acacctgggt
    81121 ctgttgtcaa gggggcgacc ttggctgccg gctggcaggc tggagtgatt caggggaatc
    81181 aggtcttgat tgatcagccg attcaatttg gtggctccca gccgattaat tcttggttta
    81241 ccagcggtca gcaccctatt actgctagtc aggcgctgga atattcatca aatacttaca
    81301 tggttcaggt tgccttaaga atgatggggc aggattacgt gactggtatg accttggcca
    81361 atactggtat gaaggaaacc atgaaaaaat tgcgggcagc ctatgccgaa tttggcatgg
    81421 gagtggcaac tggcgttgat ttgcctggcg aatccagtgg ctacctcata gatcaatata
    81481 atactgcaaa tgttttgaca gaggcctttg gtcagtttga taactataca accatgcaac
    81541 tggcccaata tgtctcaact attgctaatg gcggcagtcg ccttgcgcct cacattgtag
    81601 aaggcattta tcaggataat gaccagtcag gaccaggtaa gctaagtaag gctattgaga
    81661 ctaccttgtt aaacaaggtg cacttagctg ctgatagttt agcgattatt caggacggtt
    81721 tttatcaggt ggtcaatagc ggtagtggct atgctacagg tagggctctt gcaggaggtc
    81781 ctgttaccat tagtgctaaa accggtaccg cagaaaccta tgctaaggat aaaaatggtc
    81841 aggctttatc tacctttaac ttgaatgttg ttgcctatgg tccgagtgct agtcctcaaa
    81901 ttgctgttgc tgtcatgtat cctcatgcga cagactctct agccaaggca catcaatacg
    81961 tggctaagga tatcattaat ttgtacatga agatgtataa aaaccaataa aggagaaacg
    82021 agtgctttac cctataccaa tcgcaaaatt aattgaaagc tattctaaat taccagggat
    82081 tggtgttaaa acagcgacaa gattggcttt ttacaccatt ggaatgtctg atgaggatgt
    82141 gaatgatttt gccaaaaatt tattagcagc taagcgagaa ttaacctatt gctctatctg
    82201 tggcaatttg acagatgatg atccctgcca tatttgcaca gatagcagtc gggataaaga
    82261 gatcatttta gttgttgagg attccaagga cgtttctgcc atggaaaaaa ttcaagaata
    82321 tcatggctat taccatgtgc tgcatggctt gatttctccc atgaatgggg ttggcccaga
    82381 tgacatcaat ctaaagagcc taatcacgcg tttgatggct ggagaggcaa cagaggtcat
    82441 tgttgcaacg aatgccacag cagatggaga ggcgactgcg atgtacatct cacgtctcct
    82501 aaagcctgct ggtatcaagg tgacgcgatt ggctagaggc ttggcagtag gatcagacat
    82561 tgaatatgct gatgaggtaa ccctgctgcg agcgattgaa aatcggacag aattatagct
    82621 tagcccattt tcagctctct gtcattagcc cttatgccat gtgataaggc cataaaggaa
    82681 ggcagatttt gtcagagtct tttgaaaagc aagctcgttt ttgttataat aagtggtagt
    82741 ctaattcaga tagggaaggt tatcaatgtc taaacaaacc ttaattttat tatacggagg
    82801 gcgttcggca gagcgtgaag tatcagtgct ttcagctgag agcgtgatga gagcagttga
    82861 ttacaccaaa ttttttgtta aaacctattt tatcagccag acaggtcagt ttatcaagac
    82921 acaggaattc tctagtcggc cgaccttaac agaaaggctg atgaccaacg acactattag
    82981 gctagagcag cagataaggc ctagtgatat ctacgaggag ggggctgttg tttttccagt
    83041 cttgcatggc cctatgggag aggacggttc tattcaaggc tttttagagg tgctaaaaat
    83101 gccttatgtg ggaactaata tcctctcatc aagtgttgca atggataaga ttaccaccaa
    83161 aagggtccta gagtcagctg gtatcccaca ggttgcttat accgtttata ttgaggggca
    83221 ggatttagac aggtgtctgg cagagactga ggcagtctta agctaccctg tgtttgttaa
    83281 gccggccaat atgggctcat ctgttggtat ttctaaggca gaatcagagg aggagttgcg
    83341 tgcagctatc ctgttggcct tgacgtatga cagtcgtatc ctgattgagc aaggggtttt
    83401 ggcaagagag attgaggttg gactgcttgg taataccgat gtcaaatcaa cccttccagg
    83461 agaggtagtc aagaatgttg acttttatga ttatcaggcc aaatacattg ataatgagat
    83521 cacaatggct attccggcag ctattgacga atcagctatg acaagcatgc gtacctacgc
    83581 agaaacagcc tttaaggcta ttggtgcttg tggcctgtcg cgttgtgatt tcttccttgg
    83641 tcaggacggt cagatctacc tcaatgaatt aaataccatg cctggcttta cgcagtggtc
    83701 catgtatccc ttgctctggg agcatatggg actgagctat gctgagctta ttgaggagct
    83761 agtcagatta gcacaggaaa tgtttgaaaa gcgtgaaggg catttaatat aagagacaaa
    83821 ggacggaagg agatatagca atcctctgtc ctttcgtttg gcctgattgg tagcgttttt
    83881 tggtcagaag cctttaaagc cctatcgtct acggttggct gtgccagctt tagcctgtct
    83941 atgaaggatc agcctgtagg cataaagtga aatagaaaga atattcctaa tatgttatgc
    84001 tata
//
LOCUS       DARYLJ010000002        69977 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYLJ010000002 DARYLJ010000000
VERSION     DARYLJ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69977
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(250..336)
                     /locus_tag="TU746_000081"
     tRNA            complement(250..336)
                     /locus_tag="TU746_000081"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(300..302),aa:Ser,seq:gga)
     gene            complement(396..1031)
                     /gene="trmB"
                     /locus_tag="TU746_000082"
     CDS             complement(396..1031)
                     /gene="trmB"
                     /locus_tag="TU746_000082"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL0890480.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            complement(1031..1822)
                     /locus_tag="TU746_000083"
     CDS             complement(1031..1822)
                     /locus_tag="TU746_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL0890481.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(1885..2919)
                     /locus_tag="TU746_000084"
     CDS             complement(1885..2919)
                     /locus_tag="TU746_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890482.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(2923..3648)
                     /locus_tag="TU746_000085"
     CDS             complement(2923..3648)
                     /locus_tag="TU746_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890483.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            4185..4583
                     /locus_tag="TU746_000086"
     CDS             4185..4583
                     /locus_tag="TU746_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890484.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            5036..5455
                     /locus_tag="TU746_000087"
     CDS             5036..5455
                     /locus_tag="TU746_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL0890485.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            5452..5748
                     /locus_tag="TU746_000088"
     CDS             5452..5748
                     /locus_tag="TU746_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL0890486.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(5918..7180)
                     /locus_tag="TU746_000089"
     CDS             complement(5918..7180)
                     /locus_tag="TU746_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL0890487.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(7181..7708)
                     /locus_tag="TU746_000090"
     CDS             complement(7181..7708)
                     /locus_tag="TU746_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0890488.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(7701..8144)
                     /gene="tsaE"
                     /locus_tag="TU746_000091"
     CDS             complement(7701..8144)
                     /gene="tsaE"
                     /locus_tag="TU746_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL0890489.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            complement(8510..9970)
                     /locus_tag="TU746_000092"
     CDS             complement(8510..9970)
                     /locus_tag="TU746_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL0890490.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            10229..11040
                     /locus_tag="TU746_000093"
                     /pseudo
     CDS             10229..11040
                     /locus_tag="TU746_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            11392..12384
                     /gene="manX"
                     /locus_tag="TU746_000094"
     CDS             11392..12384
                     /gene="manX"
                     /locus_tag="TU746_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL0890491.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            12555..13364
                     /locus_tag="TU746_000095"
     CDS             12555..13364
                     /locus_tag="TU746_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL0890492.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            13380..14291
                     /locus_tag="TU746_000096"
     CDS             13380..14291
                     /locus_tag="TU746_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0890493.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            14425..14808
                     /locus_tag="TU746_000097"
     CDS             14425..14808
                     /locus_tag="TU746_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL0890494.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(15129..16181)
                     /locus_tag="TU746_000098"
     CDS             complement(15129..16181)
                     /locus_tag="TU746_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL0890495.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            16781..18058
                     /gene="serS"
                     /locus_tag="TU746_000099"
     CDS             16781..18058
                     /gene="serS"
                     /locus_tag="TU746_000099"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL0890496.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            complement(18290..19060)
                     /locus_tag="TU746_000100"
     CDS             complement(18290..19060)
                     /locus_tag="TU746_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL0890497.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(19057..19923)
                     /locus_tag="TU746_000101"
     CDS             complement(19057..19923)
                     /locus_tag="TU746_000101"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL0890498.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            complement(19932..21296)
                     /gene="accC"
                     /locus_tag="TU746_000102"
     CDS             complement(19932..21296)
                     /gene="accC"
                     /locus_tag="TU746_000102"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL0890499.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            complement(21330..21752)
                     /gene="fabZ"
                     /locus_tag="TU746_000103"
     CDS             complement(21330..21752)
                     /gene="fabZ"
                     /locus_tag="TU746_000103"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL0890500.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            complement(21749..22222)
                     /locus_tag="TU746_000104"
     CDS             complement(21749..22222)
                     /locus_tag="TU746_000104"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL0890501.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            complement(22224..23456)
                     /gene="fabF"
                     /locus_tag="TU746_000105"
     CDS             complement(22224..23456)
                     /gene="fabF"
                     /locus_tag="TU746_000105"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL0890502.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            complement(23472..24206)
                     /gene="fabG"
                     /locus_tag="TU746_000106"
     CDS             complement(23472..24206)
                     /gene="fabG"
                     /locus_tag="TU746_000106"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL0890503.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            complement(24223..25143)
                     /gene="fabD"
                     /locus_tag="TU746_000107"
     CDS             complement(24223..25143)
                     /gene="fabD"
                     /locus_tag="TU746_000107"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL0890504.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            complement(25156..26142)
                     /gene="fabK"
                     /locus_tag="TU746_000108"
     CDS             complement(25156..26142)
                     /gene="fabK"
                     /locus_tag="TU746_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL0890505.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            complement(26337..26561)
                     /locus_tag="TU746_000109"
     CDS             complement(26337..26561)
                     /locus_tag="TU746_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL0890506.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            complement(26619..27593)
                     /locus_tag="TU746_000110"
     CDS             complement(26619..27593)
                     /locus_tag="TU746_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL0890507.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            complement(27593..28027)
                     /locus_tag="TU746_000111"
     CDS             complement(27593..28027)
                     /locus_tag="TU746_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0890508.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            complement(28107..28898)
                     /locus_tag="TU746_000112"
     CDS             complement(28107..28898)
                     /locus_tag="TU746_000112"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL0890509.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            complement(29218..30354)
                     /gene="dnaJ"
                     /locus_tag="TU746_000113"
     CDS             complement(29218..30354)
                     /gene="dnaJ"
                     /locus_tag="TU746_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL0890510.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            complement(30511..32340)
                     /gene="dnaK"
                     /locus_tag="TU746_000114"
     CDS             complement(30511..32340)
                     /gene="dnaK"
                     /locus_tag="TU746_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL0890511.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            complement(32745..33314)
                     /gene="grpE"
                     /locus_tag="TU746_000115"
     CDS             complement(32745..33314)
                     /gene="grpE"
                     /locus_tag="TU746_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL0890512.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(33359..34393)
                     /gene="hrcA"
                     /locus_tag="TU746_000116"
     CDS             complement(33359..34393)
                     /gene="hrcA"
                     /locus_tag="TU746_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL0890513.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            complement(34843..35415)
                     /locus_tag="TU746_000117"
     CDS             complement(34843..35415)
                     /locus_tag="TU746_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0890514.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            complement(35412..36155)
                     /locus_tag="TU746_000118"
     CDS             complement(35412..36155)
                     /locus_tag="TU746_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL0890515.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            complement(36145..36852)
                     /locus_tag="TU746_000119"
     CDS             complement(36145..36852)
                     /locus_tag="TU746_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0890516.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            complement(36927..38264)
                     /locus_tag="TU746_000120"
     CDS             complement(36927..38264)
                     /locus_tag="TU746_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL0890517.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            complement(38279..38545)
                     /locus_tag="TU746_000121"
     CDS             complement(38279..38545)
                     /locus_tag="TU746_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL0890518.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            complement(38809..39924)
                     /locus_tag="TU746_000122"
     CDS             complement(38809..39924)
                     /locus_tag="TU746_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL0890519.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            complement(40121..40360)
                     /locus_tag="TU746_000123"
     CDS             complement(40121..40360)
                     /locus_tag="TU746_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL0890520.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            complement(40411..41355)
                     /locus_tag="TU746_000124"
     CDS             complement(40411..41355)
                     /locus_tag="TU746_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL0890521.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            complement(41584..43023)
                     /gene="gatB"
                     /locus_tag="TU746_000125"
     CDS             complement(41584..43023)
                     /gene="gatB"
                     /locus_tag="TU746_000125"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL0890522.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            complement(43023..44489)
                     /gene="gatA"
                     /locus_tag="TU746_000126"
     CDS             complement(43023..44489)
                     /gene="gatA"
                     /locus_tag="TU746_000126"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL0890523.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            complement(44489..44791)
                     /gene="gatC"
                     /locus_tag="TU746_000127"
     CDS             complement(44489..44791)
                     /gene="gatC"
                     /locus_tag="TU746_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL0890524.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            complement(45265..45822)
                     /locus_tag="TU746_000128"
     CDS             complement(45265..45822)
                     /locus_tag="TU746_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL0890525.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            complement(46439..47221)
                     /gene="codY"
                     /locus_tag="TU746_000129"
     CDS             complement(46439..47221)
                     /gene="codY"
                     /locus_tag="TU746_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL0890526.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            complement(47393..48607)
                     /locus_tag="TU746_000130"
     CDS             complement(47393..48607)
                     /locus_tag="TU746_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL0890527.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            48894..49346
                     /locus_tag="TU746_000131"
     CDS             48894..49346
                     /locus_tag="TU746_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL0890528.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQEAKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIP
                     DKEEVDLIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
     gene            complement(49632..51020)
                     /locus_tag="TU746_000132"
     CDS             complement(49632..51020)
                     /locus_tag="TU746_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0890529.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            51092..52057
                     /locus_tag="TU746_000133"
     CDS             51092..52057
                     /locus_tag="TU746_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL0890530.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(52177..54192)
                     /gene="recG"
                     /locus_tag="TU746_000134"
     CDS             complement(52177..54192)
                     /gene="recG"
                     /locus_tag="TU746_000134"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL0890531.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(54556..56010)
                     /locus_tag="TU746_000135"
     CDS             complement(54556..56010)
                     /locus_tag="TU746_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890532.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            complement(55947..56627)
                     /locus_tag="TU746_000136"
     CDS             complement(55947..56627)
                     /locus_tag="TU746_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0890533.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            complement(56624..57217)
                     /locus_tag="TU746_000137"
     CDS             complement(56624..57217)
                     /locus_tag="TU746_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL0890534.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            complement(57198..58880)
                     /locus_tag="TU746_000138"
     CDS             complement(57198..58880)
                     /locus_tag="TU746_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890535.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            complement(58873..60636)
                     /locus_tag="TU746_000139"
     CDS             complement(58873..60636)
                     /locus_tag="TU746_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL0890536.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            complement(60682..61464)
                     /locus_tag="TU746_000140"
     CDS             complement(60682..61464)
                     /locus_tag="TU746_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890537.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            complement(61461..62483)
                     /locus_tag="TU746_000141"
     CDS             complement(61461..62483)
                     /locus_tag="TU746_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0890538.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            complement(62485..63369)
                     /gene="isdE"
                     /locus_tag="TU746_000142"
     CDS             complement(62485..63369)
                     /gene="isdE"
                     /locus_tag="TU746_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL0890539.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            complement(63353..64258)
                     /locus_tag="TU746_000143"
     CDS             complement(63353..64258)
                     /locus_tag="TU746_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL0890540.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            complement(64487..68238)
                     /locus_tag="TU746_000144"
                     /pseudo
     CDS             complement(64487..68238)
                     /locus_tag="TU746_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            complement(68440..69855)
                     /locus_tag="TU746_000145"
     CDS             complement(68440..69855)
                     /locus_tag="TU746_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0890541.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
BASE COUNT        20223 a        16811 c        13687 g        19256 t
ORIGIN      
        1 tttctaatga gattgttagt gcttctcatg ataagtctta tgggactttt ttgtactcaa
       61 aaagccctat catttccata ctggataaat ccactacaga aatgatagag cctaaaatat
      121 atgttcacca attggataag ttaaaagaaa aaaatgacca tcaggtcaaa agcatttttc
      181 aaaatctcaa atttgacggg tgaaaaacag gcgaagactc cgaaaccctt gatataccaa
      241 taggataaaa ggagaggagg ggattcgaac ccccgagccc cgttaaggac tacacgcttt
      301 ccaagcgtgc gcactcggcc actatgcgac ctctccaagt aaaaggctga tcaactcaac
      361 ctcagtagtg tatcatattt ttgtcaaaat agctactaga atgttgcttc taggcggtaa
      421 ataatctgtc cctttttagc aaatctagcc tcatactcag tcatcacatt tccttgataa
      481 tcactagcat gtaaatccag ccagacctgc ttgagggtca taccgtactg tgaaaagctc
      541 gctaggctat actcaaataa gccacgatta tctgttttaa aatgaatttc accattttcc
      601 ggcaaaatct gcttataagt gtctaaaaag gatttgtagg ttagtcgacg cttttcatgc
      661 ctgcttttgg gccaaggatc tgaaaaattc aaatacatca tatcaacctc accggcatcg
      721 aaataattgg tcaggcttga cccatcaacc cgcaagagcc taacattagg agcctgagag
      781 gctaggacct tatctaaagc atagcttagc actgatagct gaatgtcaat gccaatatag
      841 ttgatctctg ggtttttcaa cgccatacct gtgataaagg ctcccttgcc tgagccaacc
      901 tcaatatgga tcggatgatc attaccaaag acctcacacc agcgcccctt agcagcctcc
      961 ggctctaaaa tgacatagtg aggattgttt tccaagtgct cctgcgcacc ctttcgtttt
     1021 ctaactcgca ttatttcttt ctaaacattt ctctaaattt tctaagagcg taaatctctt
     1081 gattgacatg ctccatatct ctcttatcaa agcaccttaa aatctgagtt agataagaga
     1141 attgagcata ccaaataatc ttttgcatga ccttatcatt atttttatag ccataatagg
     1201 atagccagtc tgcccatcgc gaccgaggaa tatagtggct tagcaaataa gccacatcat
     1261 acattcgatc tgttaggcgc acacaatccc agtccaccaa aaaaatcatg ccactggtgg
     1321 taatcaccca gttgctatgc ttgatatcac catgtacaat cgtggccacc tcagagcgaa
     1381 attcaggtag gctgcgcttt agctccttga cgatagcctg taaataagaa ttctgttgaa
     1441 tttgcaaagg tgcattttgc tcaaagtcta ctaaaaggtc ataaggattt tcaattttat
     1501 agttgagctg aagcaattga ttaaccaact gcttggactt gtggaggcgc agcagaatat
     1561 ggacgatttg cttactgttc atatcctctc tagtcagagt acgaccattg agccactctt
     1621 gagcactcat catatcgcca ttccccatac gctttgccca aagcaattgt ggggcaatct
     1681 gttcctttgc taaggcaggt aggattggtg ttgtattaag cttgataaag acgctttcgc
     1741 catttggata ggtccctttg taggctttgc cactttttcc gcgcaaggga gtcaatacaa
     1801 gatcctgttc ggttgttgtc accttatccc ctccttttct atcttctgta accagttatc
     1861 cctattttac ttgttttaaa ggacttagtc aatcatcttc tttaacttgt acggtaagta
     1921 aagaagattt aataatccca tcgccacaat caacacaaga gcattttgcc aagaacggca
     1981 gagcacaaga ttgacgataa gcatcaaacc acttaattgc ctcaacaaag aaagtagatt
     2041 cctttgctta tgctgtggtt tagtcgggta aagcccactc atataatggt aatcataatg
     2101 atgataaagt gataataact gaaaaagact tagataatga aagaccaagg ccaagcctac
     2161 tgctaaataa gggttggaaa taaaggcaag tgacaagcaa ctaagcaaca acagacgtaa
     2221 ccataaccct agataatcag agctgcgtaa aaatgctctt aaatataggt ttgtccaaac
     2281 ctttttacta tctgccttga taagcttaag tataggattc aagtaaggcc tttccttaac
     2341 cttggttgag attcctttaa catttgtaaa caaagcataa aactttaaaa tggcctgctg
     2401 gcgatctgcc tcaaaagcaa tcgctttttc ccaatcaagc cccttggagc tcaaaaagct
     2461 tgccacctta cgctttaaca gtaagcgctt agccagcacc aaaacaccaa gcaatagcac
     2521 aaaggcaagc aaggaaacac caagcctttg aaacaaagga aataaaggta acagcaagac
     2581 cgtttgaagg ctagaccaaa gaataaagga caagcgctct gctgacctga tatgggcaat
     2641 aacctctgcc tccttggtca gcaaaaaatg ctgatcagcc ttttcaagat aggtagcaac
     2701 tgaccccaga ttaagcaaaa acaagacagc aatcaacaaa cctagctgaa tcggtagagg
     2761 attagcagga aaatgcttga gtagttgact gtactgaaaa agaataaagc ccaaaagaaa
     2821 cagcaagaca agaacaaaat gatcattaaa gacataaggc agatacttgg tatgcttgtg
     2881 ctgaaactcc tgacgacgct tacgaaataa tgccttcata gcttacccct cttttgtcag
     2941 cgctaggtaa atgtcattaa gactagctga agcatctcca aagactgcct gcaaatccgc
     3001 cagagtccct tgtgcacgca cctgtccctg atgcaatatc acaaaacggt cacacatttt
     3061 ttctgccgaa tccagcacat gggtactcat tagaattgac ttgccctttg ccttttcaac
     3121 ctctaaagcc ttaatcaaat cagcaattgc taaggggtca agccccaaaa agggctcatc
     3181 aagaataaaa agactagggt caatgacaaa agcgcaaata atcataacct tttgcttcat
     3241 tcccttagaa aaatgcaccg gaaaccaatc cagcttatcc gtcaaacgaa acagctctaa
     3301 gaagggctca gctcgcttat gtgccagctc cacatcaata tcataggcca tagctaccgt
     3361 attgatatgc tctgctaagg tcagctcctc atacaggctt ggtgtttctg ggataaagcc
     3421 aattttcttg cgataatcag cttcatgctc cgccaaggtt aagccatcaa tggaaatcct
     3481 tcccttatat ggctttaaaa acccaataat ttcattaatc gttgttgact taccagcacc
     3541 atttagacca ataagcccta ctagctctcc atttccgaca gaaaagctaa tatccttcaa
     3601 aactggaata ttaaggtagc ctccagtgac attctcaatg tttaacatat catttctttc
     3661 taatatctaa tctattgtag ctttgcatac tagcttccct agatgacagg ttattagcct
     3721 agacagatag gacttactag gcaatgcttt gtcatcatca gcctatccag cgctttgaag
     3781 cactgataag accaattagc ttgaccctac ttaagaaagc tggggcagct aatactaagg
     3841 gtacacttat attagctatt ataacaaatt tctgcacaga gcgttaactg ttttgatcaa
     3901 tgctcccatc agctaaaaac gctgagtgaa tctgaagtct attttaagat catcaagaaa
     3961 aaggcctagc tataaaaaca gaggctatat tagcttgatc tatcagtcct aaccatctat
     4021 cacatcatat tcgaatgacc tggtgatcct aaatagcagc tcatctaagg cgtcatctaa
     4081 aaaatcatga taatattatc ttattgtatt gaatttttaa taatataatg ttatcgttaa
     4141 catgtaaata agtgttgcgt ctttaatgac aaaggaggta tgttatgaat ttgtcacgct
     4201 ttttaacatt tggtttggta tcactttcag cactttcaat ttcaggccta gtccaaacag
     4261 aggctaaggc taacgaatgg cagactatct ttgaaaagcc acaggaggtg gttatcacag
     4321 atggctggca aactatctct gaaaagcctc aggaagtaag cacggctaac gaatggcagg
     4381 tcagctctga agaagctcaa gagtctgttc ctgataaatt ctcacaaaac gaagacccta
     4441 gcctatgggc tgttcctgat aaattctcac aaaacgagga ccctagccta tgggccgttc
     4501 ctgataaatt ctcacaaaac gaggacccta gcctatgggc cgttcctgat aaattctcgc
     4561 aaaacgagga ccctagcctg tagtaaagcc atccgcactc gattgaagat aaggcctatg
     4621 ttgctgacgc ttcaatcttt ttttgttcta aaagctttct cagccttaac tgtcaagaag
     4681 ttccagcacc tcatactctc tgaaactctt gtccttacaa atattgtgcc atgtcactac
     4741 cgtacgatag tgcgcaaatg cacacctttg acggacctag cttgcagcaa gtagcaggct
     4801 tagttatgtg cttaaccata attgcttagt ccattatcat gattcaaaag gctttgctag
     4861 tcatgtggtc gataaccatt agcaccagct ataaacaatt gcaatataga ccagtacatg
     4921 ctaagataac tatagtatga gatagctatg gtcactgagc aactactgat ttcttattct
     4981 aaaattattc aactactgat ttgagccatt gctacgcaga cgaaaggatt atcacatgga
     5041 aaattgtatc ttttgcagca ttattagcgg tgagattccc tcctccaagg tttatgagga
     5101 tgagcaggta ctcgcttttt tggatatttc gcaaacaaca gcgggtcata ccctcttgat
     5161 tcctaaaaag catgtccgaa atatcctagc aatggacgcc gagacagcta gccagacctt
     5221 tgaacgatta cctaaaatcg ctcgcgccat tcaaaaagca acaggtgcta ctgcaatgaa
     5281 cattattaat aataatgaag agctagctgg tcagactgtt tttcacgcgc atgtgcacct
     5341 cgttcctcgc tacagccaag aagacgggat cgctattcag tatacaacac atgagcctga
     5401 cttcccagcc ctagcagcct tggcacaaca aattagtcag gagattagcc aatgactcta
     5461 aaaacaatga ccacaattgg tctcacatcc gttttagcct accaagtgta tcgtaaacgt
     5521 catcaaatca aagaaactct agtagccatg caaacctcta agaaggctat ccaggccgat
     5581 gttgatagga ttaaggcaaa tctcgccatc attcaaaagg aggctcgaac gcttcaagca
     5641 gcaggaacag aattagccta caaatggcag gcctttaacc aagaagctca ggcccatctg
     5701 actgaaatcc aacaacgtat gagcaagtac cagcaggaaa ccccataagc ctaagcagac
     5761 taccaagcct caaggtgaca aaaaagggct ctatcgtttc tgtagtggac aagtccgcta
     5821 tagggattat gggctctttt tgtatgtaca aaaaagacga agaaatcact cacaggatca
     5881 agccttgatg agatttcttc gtttttttgg ctgtacccta aggcgctgct ggcgtaccag
     5941 tggttgcacc acttgattgc tgctctgctg gtgagtctgc ttgagggcta ggagtcacat
     6001 tagctgctcc tgactcttgt gtaccagctg ttgtgtcctg atagctgctg ctagaggacg
     6061 tctctgagga ataggttgag tactgggtag atgagtctgt ataggccggt aggctacctg
     6121 aattgtaata atagctgcta tcctgagtag actgagtttt taacgagcca taaaggtttt
     6181 cgtaaactgt ggcagtcgtt tttagctgac taagcttttc aaggcctaat tcagcacgaa
     6241 tgcgattttg gatttctaaa agatgatctg aggtcacaat ttgataggag ccgccatctg
     6301 acaaggtcgc tccctcaccc tttagctgat aggttttgat atttttaagg gcgtctgtat
     6361 agcctaaaag attaggaatg gttcgtgatg atatttcaat gttggtttgc atattaccac
     6421 taacagctga caagatcttt cggtaggagc tgatactgtt aagggcaaga atctttttca
     6481 gcaccttttg aataacctcg cgctgacgct tctgccgacc gtagtctccc tctggatcat
     6541 catagcgcat tcgagcatag accaaggcct gctctccatt tatcttgtga gttcctggtg
     6601 caacggtagc ctgatactca ggctcattat ctgcaataga gataggaaag tcaaattcat
     6661 tggtaacagt aatgccacca acagcattaa ccaaatcaat gagcccttgc atgttaatct
     6721 gaacgtattt gtcaatcgtg atattcagca agtcctgaac ggtcatgata gccatttggg
     6781 caccaccagc tgcataagca gcattcagct tagcttctgc tccattcatc tcattatcat
     6841 ttggacctga caaagtgatg agaatgtctc tttctaagct tgtcatggtt gtctttttgg
     6901 tcttagggtt aatcgtaacc agaatcatag aatcactatt tccttgccag gtagaggttc
     6961 tgtgagacga tcctgtgtca actcccatca atagaattga aaagggctct gtctgttgaa
     7021 tggcatcact ttttttggag gacgttgcaa aatccttaaa ggtctttgac aattctccag
     7081 ttgaaaaggt ataggcattg gttaggtaaa ctcccatagc ccccaaggtc aacagcacaa
     7141 tagctgtcag cattaaaaag attttttttc caattttcat ctattcacgt tccagatatt
     7201 tacgcataag gtaaacatcc tgatagtctc catttcttga tttgacgtcc tttcttttga
     7261 cgccctctat tttaaagcca tatttctcat aaatatgata ggcacaagta tttcgagcct
     7321 gaacctccag ctccaaagca caaagctgct ttgtttctct ggcccaatca agggtagtct
     7381 ccatcaaaag ctgtcctagg ccatgattgc ggtagggttt caagaccagc ataaagcaat
     7441 cgccaacata gctagtctca cgatatgctt tgccagctat atttagcaga ccagctaata
     7501 tatctcccac ctttagcaaa aggcaaatat ctgtcaaaga ctcctgacta gcctctagaa
     7561 aacactcaag cacctctacg gtagcagcta tgacgtcctc agtccctgtg ataaaatctg
     7621 tctcatcagc agcttcttta attagagtga tcaaagctga cgcatctgag gccttggcct
     7681 cttcgattgt caccacctgc tcagacatgc ttaagctcct caagaagtgc ctctgatcga
     7741 tgaccatgtg ctagataatc aacctgccgg cctgtttctg tttttgttat taaaatttca
     7801 aggtagtcat gcagggttcc cttggctaaa agctcgcccc actcaatcac agtaacccca
     7861 ccaccaaaga taaaatcatc taaatcaata gagtccggat catcaccaat ccgataaaca
     7921 tctaaatgat acaagggtag tcttccctca tattctcgag cgatagtata ggttgggctt
     7981 ttaatcatct gatcaatccc caaaccctta gcaaccccct tggtcagcgt tgttttacca
     8041 gcacctaagt caccagtcaa gacaagcaca tctcctgcct ttagctgtct accaatgcct
     8101 tgcccgtaag cgattaattc attctcattt ttgctataaa acataaggct attataacag
     8161 aaaaaaaacg gtcttccaag cctaagccag cctgtcagca aaatattcta ggctcgtcag
     8221 tcctcatata atgtcgtcaa agctcaatca gctttaacat ctcataaatc aaaagagcca
     8281 gcagcaaatc acatggacct aacatcatgg cattctgctg tgatagccag ggctgaatgc
     8341 tctagaaatc aacccgcagc tctaaaacct taagacttag cctaaatata ggactaggaa
     8401 aaggtggcaa tgcctatgag cttagaaagt ccatagtccc agtccaaacg gtaatccctg
     8461 tctttattgt cccagcaaaa aagaggcacc taagtacctc attagtcgtt tacaataacg
     8521 ctaaaatgat aaaattcaaa acaaataaga aggttgctcc ccaaagaatc gggtgaatct
     8581 ccttggtttt gcccttcaca agcttcacca agcaatagaa aataaaggag ccagccacac
     8641 cgtatgaaat agagtagcaa agtgccataa agaaagcagc aaagaaggac ggtagggcaa
     8701 cgtcaaagtc gctccaatca acatcaagga aggacgatac catcataacc ccgacaatga
     8761 ttaaggctgg tgcagtcgca gcggctggaa caattcccac gatcggcagc agtaaaacag
     8821 ataagacaaa gcagacagca gttgatacag ctgttagacc tgtacgtcct ccctctgcaa
     8881 taccagcagc agactcaacg taggttgtgg tatttgaggt gccaaataaa gctccgattg
     8941 aagtaccaat agcgtcagca aagagcgcac ggtccatttt tgagctaaag ccagagctgt
     9001 tttccaaagc tctctcatcc tcctcagaga aaatccctgt tcgacgacca gtcccaacaa
     9061 aagttccaat cgtatcaaag gtatcagata gactaaaggc aaagatcgtc attaaaacaa
     9121 gcggcaagcg acttgaatca ctaaacagtg acgccatgcc accaaaggca gccaagaatg
     9181 ttgtccctaa ttcagcaaag gctgagctga tgtgattgtc tgcaaaatta acagcagaaa
     9241 gatcaaccac tccaatagga ataccggcta aagttgtaac tgtaatacca attaggatgg
     9301 ctccacgaac gttcttaagc acaagcactg ctgttagcag cagaccaaaa actgctagca
     9361 aaacactcgg atcggtgaag gttgaaatag ctggaaccac accaccatta gcattaacag
     9421 agaagacgcc attagcaaat gtttcagcag ttgccttagc tggctcaaca ccatttacag
     9481 taacaatctc agcagatgat agcgaaaagg tgatcaggtt agcattttta aaacctagat
     9541 aagcaacaaa gactccaata cctccgccaa tagcatgctg caggcttact ggaatagcct
     9601 tgataatgct cttgcgaagc tttgtgacag tgataaagat attaaacaga ccacaaagaa
     9661 agacaatagc caaggcctcc tgccaagaaa atcctaagct aaaaacaaca gtgtaagtaa
     9721 agaaagcatt aagtcccata ccaggagcca atgcgtaagg cacattagca aacaaaccca
     9781 tgatcaaggt agagatagca gctgcgatga tggtcgctaa aaacaccgct tgcgacggca
     9841 tacccgctgc actcaaaata cttgggttaa caaataagat atatgacatc gcaaaaaaag
     9901 tcgtcacacc agccatcagc tctgttgaaa ccgtcgtgcc attttctttt aacttaaaaa
     9961 acttttccat ttgaatggag tctccttatt gataggcaaa atcaaaaaag cccttatctc
    10021 atcagataag ctttttctct taaaaccaaa tgattattat cgtttttacg aacgatatat
    10081 tcatcgtaac attttatcgt tctattttca atagcttttt tcgtttattt gccatgatcg
    10141 ttcaaaattt aacagccttt ttttctatta accgtccaag cagcaatttt ctcttccact
    10201 gatcctaaaa tttgttataa tctagtgtat gactaaaaaa ctaattgcta ttgatttaga
    10261 cgggacttta ttgcatcacg acaataccat ctctacctat actcaaaaaa ccattaaggc
    10321 cgtccaagct aagggacatg aggtcatcat ctcgacagga cgtccttatc gtatggctat
    10381 tgactactac cttcagctag agctaaagac acctatgatt agctttaatg gctctttgac
    10441 ccacctacct gagcaaagat ggaaatacga gcataatgtg actcttgata aggcatacct
    10501 tctcaaactc ctagcagtgc aggaggactt ccagatggac tttattgcta gtgagtaccg
    10561 aaaagccttc tacattacca tgaataggcc tgagagcatt gaccccaacc tttttggttt
    10621 gaggccatca caccagatat ggctttacag atcgacaaaa tcacgcagga tccaaatgct
    10681 cttctcatgc aaacgcatca tgaggataag tatgccctag ccaaggccat gcgcgccttc
    10741 ttcaaggacg aaattgaggt ggactcttgg ggtggtccct taaatatcct tgagatgtcc
    10801 cccaaaaaca ttaataaggc ctatacctta aaatacctgc ttagcattta caacaaggag
    10861 cctaaggatt taatcgcctt tggtgatgag cataacgaca cagaaatgct ggcctttgcc
    10921 ggaaccggct atgccatgaa aaatgccagc cctgtgctgc tgccctttgc cgaccagcag
    10981 ctagcttact ctaacgaaga ggacggggtc gccagaaaac tagaagagct tttcttgtga
    11041 aagcaaacga aaccattgtt tttcagaaaa cgatggtttt cttaatgccg tttccgtcaa
    11101 ttgatgaaag aatttctaat attttcgtta tttttcagca tattttcttt tttatgcggc
    11161 ataaaaatcc ctttattatc aatattctac ttattcggca gcgcattatg aaaatttttt
    11221 catatttcgt aagatttttc cgaaagggct tgatttttaa gtgaaaacgt tttaaaatag
    11281 agacgttctt gaatttcgtt caagtgaaaa agaattgcca aatgctattt ggaaggagat
    11341 tattcttctt catttcaacg aaaaatattt taataaggag gaagaacaag aatgggtatc
    11401 ggtattatta ttgccagcca tggtaaattt gctgaaggta ttcatcaatc tggttctatg
    11461 atttttggtg aacaagagaa agttcaagtt gtgactttca tgccaaatga aggaccagat
    11521 gacttgtatg gacacttcaa caatgctatc gcacaatttg atgctgatga tgaaatcctt
    11581 gtactagctg acctttggag tggttctcca tttaatcagg ctagtcgtgt ggcaggagaa
    11641 aatcctgatc gcaaaatggc tatcatcact ggtctaaatt tgccaatgct tattcaagcc
    11701 tatactgagc gtttgatgga cgccaatgca ggtgttgaac aagtagccgc aaacatcatt
    11761 aaagaatcta aggacggtat taaagccctt cctgaagagc tcaatccagt tgaggaggct
    11821 tctacagcta atggtggtgg tcaagcgctt caaggagcta ttcctaaggg aactgtcatt
    11881 ggagatggta agctaaaaat caaccttgct cgtattgaca ctcgtcttct tcatggtcag
    11941 gtagcaactg catggacacc agcttctaag gctgatcgta ttattgtagc gtcagattct
    12001 gtggctaagg acgagcttcg taagcaattg atcaagcagg cggctcctgg tggggttaag
    12061 gctaatgttg ttccgatcaa taaattgatt gaggcttcta aggacccacg ctttggcaac
    12121 actcacgctc ttatcctgtt tgaaactgtt caggacgccc ttcgtgcgat tgaaggcggc
    12181 gttgagatca aagagctgaa cgttggatca atagcgcatt caacaggtaa aacaatggtt
    12241 aacaacgtat tgtctatgga caaggatgac gttgctgcct ttgaaaaatt acgtgatcta
    12301 ggtgtttcat ttgacgttcg taaggtgcca aatgattcta agaaaaacct atttgagctt
    12361 atccaaaaag caaatgtgca ataagcaatt tagaaataag aggtaggctt gtttaacgca
    12421 acaagctgtc tgcctcatct acaatgctgc gatgatatga taagcctgat gattgcttct
    12481 agacaaatca tcatcactta ataacgcttt atattgtcca ttgacaattg actcatatac
    12541 gaaaggataa caaaatgtca gatatttcat taatttctgc aatcttggtc gttatcgttg
    12601 ccttctttgc cggtcttgaa ggtatcttgg accaatttca aatgcaccaa ccacttgttg
    12661 cgtgtacctt aatcggactt gtgactggtc accttgaagc aggtgttatg cttggtggta
    12721 ctcttcaaat gcttgcactt ggttgggcaa acattggtgc tgctgtagct cctgacgctg
    12781 ctcttgcatc tgttgcagcg gctattatca tggttaaggg tggcgacttt actcaaaaag
    12841 ggattacctt tgcatactca acagctattc ctcttgcggt tgcaggtctt ttccttacta
    12901 tgattgttcg taccatttca actgtacttg ttcacgctgg ggacaaggct gctttagagg
    12961 gtaacttctc tgctatcgag cgcttccact ttgctgcact tcttcttcaa ggcttgcgta
    13021 ttgctgtacc agctgcactt cttgttgctg tgccaactga ggccgttcaa agtgtcttga
    13081 aggctatgcc agcttggttg aatgaaggta tgcaaatcgg tggtgctatg gttgttgccg
    13141 taggttacgc tcttgttatc aacatgatgg ctacacgtga ggtatggcca ttcttcgcac
    13201 ttggttttgc ccttgcagct gtgacccaat taacacttat cgctatgggt gttatcggtg
    13261 tggctattgc ctttatctac cttaaccttt caaaacaagg tggtaacggt ggaggtcgag
    13321 caggctctgc tgacccaatc ggcgatatcc tagaagacta ctagaaaggg gtaagattaa
    13381 tgactgaaca aattaaatta acaaaagctg accgtaaacg tgtttggtgg cgttcacaat
    13441 tccttcaagg gtcttggaac tatgagcgta tgcaaaacat gggttgggct tatgcactta
    13501 tcccagcact taaaaagctt tacacaacta aagaagatcg tgctgctgca cttgagcgtc
    13561 atatggaatt ctttaacact cacccatatg tggctgctcc tatcatcggg gtaacgcttg
    13621 cccttgaaga agaacgtgcc aacggtactg ctattgacaa cgctgctatc caaggggtta
    13681 agatcggtat gatgggacct cttgcaggta tcggtgatcc tgtcttctgg tttacagtgc
    13741 gtcctatcct tggtgctctt ggtgcttctc ttgcacaaac tggtaacctt gtcggtccac
    13801 tccttttctt ctttggctgg aacattatcc gtatggcctt cttgtggtac actcaagaat
    13861 ttggctacaa ggctggatct gaaatcacca aagacatgtc aggtggtatc ctacaagaca
    13921 tcactaaggg agcttctatc cttggtatgt ttatccttgc tgtccttgta caacgctggg
    13981 tatctatcaa ctttaccatc aaccttccag gcaagcagct ttctgaaggt gcctatgttg
    14041 tcttccctga gggagccgtt aaaggtgctg agctaaaaag tattcttgga caagctatgg
    14101 gtggcatgag ccttgataaa gttcaatcac aaacccttca agggcaatta gactcattga
    14161 tcccaggact tgctggatta ctacttacct tcctttgcat gtggttattg aagaaaaaag
    14221 tatcaccaat cgcaatcatc attgccttgt ttgcatttgg tatcatcgca caccttcttc
    14281 acatcatgta ataaaaatta aggaattggg ggcttcccag ttccttaatt tttggctgtc
    14341 tagagcctta gcaaaggcca gtattcagcc tgctacaagc tatattttta tgttataata
    14401 gacaaaaaca ctaaaggact tattatggca caatctttaa atcaaagggt gatccttcag
    14461 acaacagccg tctcctatct tggaatcgga ggaaaggttg ggaaaatctt acttggagat
    14521 aaggctttgg aattttacaa tgataaaaac gttgaggact tcattcaaat tccctggacg
    14581 gccattaacc aaatcggtgc caatgtttct ggcaaaaagg tcagtcgtca ctttgaaatc
    14641 tttaccgatc aaggcaaatt tctctttgct tcaaaggatt caggaaaaat cttgaaggtt
    14701 gctagagaaa caattggcaa tgacaaggtc atcaagctac caaccttggt ccagaccata
    14761 atagcaaagc tatttcatca tcaaaaaaag gataagaaat ctcattgatg ggcctgcctt
    14821 aattcaatat tacggtcata gaccagcatg ataatactct tagacatagc accatagcaa
    14881 tatgtctaag agtttttttc gttgctaaca aaaaagcttg aaaaacaagc ttacagaatg
    14941 tagacaaacc ctatcagcga tagaaaaatt gaaaatttag aaattgacta tcatataatg
    15001 aaaactctgg aaaatgctga tattacagta tttttcagaa ttcttttgtt tttttgatta
    15061 aaagaaaaag cttgaaaaac aagcttaagt gaatcctttc tacaatctaa atctaacctt
    15121 attcctcatc aatctgcaaa ggggattttc ttgtccaccc atttcaacaa attttgaaag
    15181 cctagttttt taaaaagcat cagccttgcc tgttcaacca gaaaggacaa aaaataaatc
    15241 acaatgccga cgccaaatat cagtagtggg tataaaagga taggagcatt gacaaagggc
    15301 tctgcaaaat cgcgaataat aaatttgacc agcaaggggt gtaagtgcac cagataaata
    15361 cctagagtcg ttggagacac gatcacaata aagcgtagca gcagtgtttc tgatgtcagc
    15421 ttcagcttag caaaaagaat aaataaggca atagctccca aggtcaggct aggtgataca
    15481 taccagtacc aaatatttcc caccataaat ttcatgatat aggtaactac caaagatccc
    15541 atataaaccg caataagaag cttatgacta aacctactta gctctatcct ccttagatag
    15601 gctccgataa tgtagagaat aatcagccaa gtcatttcaa agcccttgct taaggaaaat
    15661 tcatcgacct gctggttcat cagagctggg atcaacgaaa aaatagcaaa aaccagcagt
    15721 accaatcggc ctagctgctt attggataag gtattgaggc caccattgat cataggcata
    15781 aaaatcagta acccaaagta ggcggtgata taccaataat tgccactcac tatgggaaag
    15841 agggcctgac gccaattctc taagctaact ggaaagccaa atagagcaaa caaaagggtc
    15901 atcagaaagc tataaaagaa gacttgtacc caaatattaa cgattttgga atatttatag
    15961 ggcgacttaa tgcccacata gccactaatc aacgcatagc aattgaccgc cccataaaca
    16021 agaacctgaa tcatccaggt aacaataaaa taagaatctg cctcaccttc gacagttgac
    16081 cgcaagccgc cctttcccaa aacatgtgtg atcacaatca taaacatgga aatgattcgc
    16141 aataaatcta aaccgtaatg gcggttctta tctaatgtca ttacattttt acgcataata
    16201 ttagtttacc acaattttta atatttaacg atttgatttt gtctgacaac gagatttttt
    16261 gtgcctctga cctaagctct acttgtcatc agccttttgt attactgacg ctccgtgaca
    16321 gacacatgaa aaagttttag caagaaaaga aagctttctg tatttcaagg atatgtcttg
    16381 ttttttatag actttactat aggaaaaaca ttgaaagtgt ctactctaat tccaaaataa
    16441 ctagttcgcg cgtttgatgt agctgacact catttgggag tttacttttt ctcctttttt
    16501 gttataatag gtctagcgga taagtagtct ggctctgtct ttcagagagt ctgtggttgc
    16561 tgaaaacaga tagaggagtc atacgaaatt ctaccgtcta ccaattaaat atgaattaag
    16621 tgcacagatt gtgaagctgg atggaaccgc gcttaggcgc tccagtgtat tcataggctg
    16681 tgctttttta tctcgtcaga aataaaaaag cgatcagcta gctttgctca tgctatttta
    16741 taactgacta tcttatcacc agctcaaagg agatttattt atgctagatc ttaagcgtat
    16801 tcgtactgat tttgatactg ttgctgctaa gctcaaaaca cgtggtgtgt cagaagctat
    16861 cctaacctct ctaaaagcct tagatgaaca gcggcgcacc ctgcttgttc aaacagaaga
    16921 gctaaaagcc cagcgtaata tcgcctctgc tgctatcgct caagccaaac gccaaaagga
    16981 agacgccagc caacagattg ctgacatgca gcagctagct gctaacatca aggcaattga
    17041 tgctaagcta gctgacattg accaagaaat taccggtatc atcactgttt tgccaaatac
    17101 tccccatgat tcagttccta ttggagctga tgaagaggac aatgtagaga ttcatcgctg
    17161 gggaaagcca cgtcagtttg attttgacat caaggcgcat tgggatcttg gagaagcctt
    17221 agatatcctt gattgggagc gtggcgcaaa ggttaccggt gctcgcttct tattctataa
    17281 aaatcttggt gcaaggctgg agcgtgccct ttataacttc atgcttgatg agcacctaaa
    17341 agagggctat caagaaatca ttcctcctta tatggttaat catgactcta tgtttggcac
    17401 tggtcaatat ccaaaattca aggaggatac ctttgagcta gatgggacaa actttgttct
    17461 tatcccaact gctgaagtcc cattaaccaa ttactatcgt ggtgacatca tagatggtaa
    17521 ggagctgcca atctacttta ctgcaatgag cccatcattt cgctctgagg ctggctctgc
    17581 tggccgcgac actcgtggct tgattcgctt acaccaattc cataaggtcg aaatggttaa
    17641 gtttgctaag cccgaaacat cttatgaaga gctggaaaaa atgaccgcca atgccgagca
    17701 tattctccaa aagctaaagc tcccttatcg tgtcttggct ctttgtactg gggatatggg
    17761 cttttcggcc gctaaaacct atgatttaga ggtttggatc cctgctcaaa acacctatcg
    17821 cgaaatctca agctgctcaa ataccgaaga tttccaagca cgccgcgcac aaattcgcta
    17881 ccgcgatgag gcagatggca aggttaagct actgcacacc ctaaatggct ctgggcttgc
    17941 tgtcggacgt accgtagctg ctatcctaga aaattaccaa aatgaggacg gctcagtgac
    18001 gattccagaa gtgcttcgtc cttatatggg tggactagag gtgatcaagc cacgttaaag
    18061 ccaaagactg gccggataag gtgccaacaa gacgattaat gggctctatc atttctgtag
    18121 tagataagga cacagtagaa atgatagggc ttttttctat gtacaaaaaa ggctctttat
    18181 caattgtagg gggacaaaga gccgattaat gagattgatc ctaacaataa agaagacctc
    18241 tgtaactcct agctaactgc tagccttaca gaggtctttt ttgatgtcct taatattttc
    18301 taaagcgctg gtagcgctga tccaataatt cctctaaggg cttggcctgt agctgagtga
    18361 tttcgtcaat taagtgtgat tttatcatct caacaatctc actcgaaaaa taaccccgct
    18421 ccggaataat ccgatcaatg acgcccattt gatacagctc agctgcggta attttcatga
    18481 gctcagcagc ttcagtagcc ctagagccat ccttccagag aatagaggca aagccttctg
    18541 ggctaagaac agcgtacatg gtgttttcca gcatccaaac ctgatcagca acagctaaag
    18601 ctaaagcacc gcctgagccg ccttcgccaa taataatagc aatgatagga accttgaggt
    18661 cactcatttc catcaagttt ctagcaatag cttcaccttg accgcgctcc tcagcaccta
    18721 cgcccggata agctcctgct gtattgataa aggtaatcac tggacgacca aatttttcag
    18781 cctgcttcat taagcgtaag gccttacgat agccctcagg gtgcggctgc ccaaaatttc
    18841 tagccagatt atcttgaaga ttttttcctt tttgaatacc aatcactgtg accggttgat
    18901 cagccaaata ggcaatccca ccaacaatag agccatcatc agcaaactga cgatccccat
    18961 gcaactccat aaactcatca aaaatcaggc tggcataatc tagagctgtc attcgaccct
    19021 ggtcacgcgc ttcctttaat attcttgcga cgtctgtcat gatacacctc catgaaatgc
    19081 caccaaatga gcaatccgat cacgcaggtc agtccgcttc acaatagcgt caacaaagcc
    19141 atgctctttt aagaactctg ccttttgaaa atcatctggt aaattttctc taactgtcgt
    19201 ctcaatgacg cgtcgaccag caaaaccaac caaggactgg ggctctgcaa taatcatatc
    19261 accctccatt gcaaagctcg ctgtcacacc acctgtggtc ggatcagtta ggatagtcag
    19321 gtaaaaaagc ccagcatttg aatgtttctt tatagctgca gaaaccttag ccatctgcat
    19381 cagactcata atgccctctt gcatacgggc tccaccagac gctgtaaaaa taacaactgg
    19441 gagccgctca ctaatagcca gctcaaataa gcgagtgatt ttctcaccaa caacggtccc
    19501 catgcttgcc atgataaaat gcgaatccat gatggctaga gcaagccttt gtcccttgac
    19561 cagagctgtt ccagtcagga cagcctcatg caagccagta gcctgcctgg ccttttgcag
    19621 cttggcttgg tagtctggaa atcttaatgg atccttggtt tcaatatctg taaacaattc
    19681 ctgaaaagag ccttcatcaa cggttaaagt caagcgctcc tgagcagaaa tcctaaaatt
    19741 ataggagcag gtcggacaaa tctttgccgg ccccagatcc ttttgataaa tcatgtgctt
    19801 acaggcagga cacttggcaa ataattcgtc tggcacctct ggaacattac gactgacaga
    19861 gcttttgaga gaattattgg gagtaatacg gatatatttg tcttttttac taaataaggc
    19921 catatctact cctaatcttt attgtagctg ggtaaaaagg tttccatcaa aaacgacgta
    19981 tcgtaatcac ccgcaatcac ttgcttgtct gaaatcaagt ccatctgaaa atcaatattg
    20041 gtcataatac cttcaatctc taactcaaac agagcccttt gcatcttcat caaagcatca
    20101 aatcggttat ctccatgaac gataatctta gcaatcatac tatcataata aggcggtatc
    20161 gtataaccac tgtaaacagc agaatcaatc ctaagcccaa cacctccgct tggtaggtaa
    20221 agatctgtaa tcttaccagg gcttggtgca aaattaaagc ttggattttc tgcgttaata
    20281 cgacactcaa tagcatggcc agtaatcaca atatcctctt gacgaactga taaaggaaga
    20341 cctgctgcga tccgcaattg ctccttgaca atgtcaacgc ctgtaacaaa ctctgttacg
    20401 gggtgctcta cctgaacacg cgtattcatc tccataaagt aaaaatcacc gctggcttca
    20461 tctaataaga actcaattgt gccagcattc tcataggaca ccgccttggc agcacgaaca
    20521 gcagcttcac ccatcctttg acgcagtgtt gtgccaatcg caatcgaagg gctttcctcc
    20581 agtacctttt gattgttacg ctgtaaggag caatctctct ctccaaggtg tatcacatgc
    20641 ccctgtgaat cacctaaaat ttgcacctca atatgccttg ccggataaat aaccttctcc
    20701 aaatacatgg caccattacc aaaggctcct aaagcttctt gactagcagc gttaaaagca
    20761 gcctctaaat cagcctcgga ttcaaccttt cggattccct tgccgccacc gcctgcagca
    20821 gcctttagca ttactggata gccaatctgc cttgcaatct caagagcctc ttgggcattg
    20881 taaacctcgc cgtctgagcc tggaataaca ggaacacctg ccttaatcat ctcagcgcgg
    20941 gcgttgattt tgtcgcccat tttatccatg acagctcctg aggggccaat aaacttgatg
    21001 ttcatttcct cgcacatggt cacaaatttt gaattttcac ttaaaaaacc aaaccctggg
    21061 tggatagcct gcgcccctgt caccacagct gctgataaga cagaattcat attgagatag
    21121 gattcctttg atcttgacgg tccaatacag atggcttggt ctgccaagat cgtatgtaaa
    21181 gcctctctat cagcctcaga ataaacagca actgtggaaa tgcctaattc tcgtgctgca
    21241 cgaataatcc gcactgctat ttcaccacga ttggcaatta agattttgtt aaacataggt
    21301 tcttttttcc tccacagacg attagtcttt tactgcccaa aagcaaaggt caaggtccca
    21361 ctagctgcta atttgccatc aacctctgcc ttggcctcaa caactgctat tgtcccacga
    21421 cgcttaataa acctagctgt catgactagc tggtctcccg gaaccacctg ctttttaaat
    21481 tttaccttgt ccataccagc gtaaaaaaca agcttgcctt tattttcctc ttttgatagc
    21541 tccaagacgc cagcagtttg tgccaaggcc tccatgatca aaacacctgg catgactgga
    21601 tactgaggaa aatgaccgtt aaagaagggc tcattgatag tgacattttt gatggcaaca
    21661 atttcatcgt ctgaagcctc taaaattcta tcaacaagca gcattgggta gcgatgtggc
    21721 aatgcctctt gaatctgttt tatatccatc atttaatgcg taccaatcct tgtccaaact
    21781 caaccacgtc ctcattggcc actaaaatct ctgtcacgat accgtcgcaa ggagcaggaa
    21841 tctcgttcat gaccttcatc gcctcaacaa ttaacaatgt ctgtcccttt ttaacgctat
    21901 caccaacagt aacaaatgga ggcttgtcag gaccggcagc aagataggcc acaccaacaa
    21961 gaggactgtc aactacttct ccttctggct cttgcagacc tgaagaagca gggattgatt
    22021 cctgtttaga gacaatctcc tgcgtcaggc taataggggc tacctcctgg tgcaaagtaa
    22081 caggctcagg agctggagct gccatcggac ggtgctcatt tttactaaat aacagctccc
    22141 catcacttga tttgaatgaa aattcgcgta ggcttgacgc atcaaactgt gccatcaaat
    22201 cctttatctc ttgaatattc attttaatcc tcccaacgct taaaggctaa tacagcgtta
    22261 tgacctccaa agccaaaggt atttgacatg gcataacgaa tatcggcttc ttttccttgg
    22321 ccaaaaataa catttgcttc aatatcatct gacagctcct ttgtcccagc tgtcattgga
    22381 acataattgt gacgtattgc ttctatggtt gcaatagctt ccacagcacc agctgcccct
    22441 agtaggtggc ctgtaaagga cttggttgat gagacaggaa cctctttacc aagcactgca
    22501 acaatagcct gactttctcc tttttcatta gcaggagttg aggtgccatg agcattcacg
    22561 tagtcaatag ctgctgcatc aataccggcc tcctgcaatg ctagattaat ggccttacga
    22621 gcaccaagtc cttctgggtg tggtgaggtc atgtggtaag cgtcacaggt attgccgtag
    22681 ccaacaatct cagctaaaat agtcgcaccg cgcttttgag catgctctaa gctttccaaa
    22741 acaagcatac ctgatccttc acccatgata aaaccgtttc gatccttatc aaatggaata
    22801 gagctgcggc ttgggtcctc agttgttgac aaggcagtca agctctggaa gcccgcaatg
    22861 gcaaattttg taatggctgc ctctgatcct ccaaccatca tcacgtcttg aagaccaaac
    22921 ttaattgtac gaaaggcatc gccaatagca tcgtttgaag aggcacaggc tgtattgatt
    22981 gacttacata cgccttgggc attcagcttc atggcaacat taccagccgc catatttggc
    23041 aaggcctttg gtagagtcat cggcttaacg cgctttggtc ctttttcatg taaccgaatc
    23101 acctgctctt caatctcttg aatgcctcca ataccagacg ctacaataac accaaagcgg
    23161 tcagaatcaa tcgcttcaat atctaggcca gcatgttcaa tcgcctctgt cgcagcatat
    23221 aaggcataca aggaatacat gtcaaagcga tttagatcct ttttgacaaa atacttatca
    23281 aatggaaaat cctgaatctc tgctgcattc ttaacagcga agtcactcgt atcaaatttt
    23341 gtgataggct taataccaat atgacctgcc tttaagcttg accaaaactc ctctggagta
    23401 tgcccaattg gggaagtcac gccataacct gttacaacta ctctgtttaa tgtcatttta
    23461 atacctctat tttattgcat tgtcatgccg ccgtcaatgg caagcacctg accagtaata
    23521 taatcctgac tagctaggaa gcttgctgcc tgagcaacct cttgcccctt gccaatacgc
    23581 ttcattggga tttgatttaa gatttgctct tgcatctttt cagaaaggac acctgtcata
    23641 tcagattcga tgaagcccgg tgcaatcgca tttacccgaa tgccacgcgc cgcaacctca
    23701 cgagcaactg acttggtaaa gccaatcaag cctgccttgg acgctgcata atttgcttga
    23761 ccgatatttc ctgttaggcc gacaacacta gacacattga tgatagcacc ctgacgagcc
    23821 tttgtcatcg gctttaagac cgattgtgtc atgttaaatg ctcctgtcag attgattttg
    23881 agaacacgct caaagtcctc ctctgacatc ttaagcatta atttatcatt agtgatgcca
    23941 gcattgttaa tcaaaatgtc cacagagcca agctgctcaa tagcctcatc aaccattcgc
    24001 ttagcatcag ccccctctga aacatctcct gagatcggca caaccttcac accgtaatcc
    24061 ttaaaggtct ccaccagctc atcagaaatc gctgagcgac cattgagaac gatgttggcg
    24121 cctagtcctg caaattgatg agccattgct agtccaatgc ctcttgttga ccctgtgata
    24181 aaaacgtttt ttcctttaat ttccatagct tagcattccc tcctattttc ccaaatacaa
    24241 ttgtaggctt ggcatatctt caacactgct gcatagcagc tttttgtcga tttttttaat
    24301 aaagcctgtt aaaaccctgc cagggccaat ctcaacaaac tgggtgatac cgttagcctt
    24361 cataacctcg atactatcat aaaaacgaac aggctccatg acctgacgcg ccaataattc
    24421 tgcaatccga tccttttcca tgaccttagc ctctgtattt ccaaccagtg gcagatcaaa
    24481 gtcctgaaat tgaatcttgc tgagctcctc tgccaacctt tgactagcag gcgctaaaag
    24541 tgctgtatgg aaaggtcctg agacattcag cggaattaaa cgcttcactc cctttgcttt
    24601 taagatttca agtgccgcat tgacagcctc agctgtccca ccaataacaa tctgtcctgg
    24661 cgtattatag ttagcaggtg acacaacacc aaccgaagaa gcctcttgac aagcctcctc
    24721 aataagccta gcctctgtat tcatcacagc taccatctta ccagagccag caggcgctgc
    24781 ctcctccata aagcgtcccc tttttgcaac tagctctagg gcagtctcaa aactcagaac
    24841 acctgccgca actagagcag aatattctcc aagagaaagc cccgccacca tatcaggatg
    24901 aaccccataa gaggttaaga tacgataaat ggagactgaa gcggttaaga ttgctggctg
    24961 cgtgtaggct gtctggttca accgatcctg gtcggtatca atgagcttgc gtaaatcata
    25021 gcctaaaagc tgactagcct gatcaaaggt gtcacgagca atggcatatt ggtcatacaa
    25081 atctcttgtc atgcctagtg tctgagcacc ctgaccagca aataaaaagg ctgtttttgt
    25141 catacttctc cttatttata tcgtttcgtt tttgtcatca gctgcaagag cttgccagcg
    25201 cttagcttct tgactaatca ctgctgctgc accatagtag atatccttta ggatggcttc
    25261 acagctttct tctgctctaa ttaagcctgc aatctgccct gccatgacag agccattgat
    25321 cacatcacca tcaatcacag cgttgcgcag agctcctgct cccatttctt cgatgtcact
    25381 agcagcctta cgatctgcta aaaattcttt ttcagcctta gcataagctg atgttagctt
    25441 atttttgata gagcgtaccg gatgaccaac aacttgagct gaaatgacag tatcaatgtc
    25501 cttagccttc aaaattttat ccttaaagct ttggtgagca ttagattcct ttgccacaac
    25561 aaatcgagtt ccaacctgaa cagcctcagc acccagcata aaggctgctg ctgcacctcg
    25621 accatctgca atcccacctg ctgcaataac tggaatagaa acagcatcta ccacctgcct
    25681 aaccaaggtc atcgttgtca atttaccgat atggccacca gcctccattc cttcagcaat
    25741 aacagcatca acgcctaatt tttccatgcg cttagccagg gcaacgctag gaacaactgg
    25801 aatcacgata atacctgcct catgaaggcg ctccatgtat ttccctggat ttccagcgcc
    25861 agtggtcacc accttgacac cttcttcgat caccaaatcg acaatgtcat ctgcaaaggg
    25921 agatagcagc atgatattaa ccccaaaggg cttatctgtg atcgctttga cacgatcaat
    25981 atttgccttg accacctctt taggagcgtt tcctccacca atgatcccaa gaccaccagc
    26041 attggagaca gcacctgcta gatcaccatc agccacccag gccatacctc cctgaaaaat
    26101 gggataatca atattaagta attctgtaat acgtgttttc ataataacct tctatgcaaa
    26161 gaaatcagga gaataatttg ataatcaaac tatcataata agaagaaaga gcgagttaga
    26221 gcctgaaaga gggtctaatc tcaccctgat ggttcgatta ttacatatca attgaccaac
    26281 taaagcagtt cattaatcag caggctggtt aatcagtatt ctcgcttgtt tgagctttat
    26341 tttgtttttt cttcaacgta ggcaacaagg tcaccaactg tgtttaagcc ttcttctgtt
    26401 tcgatttgaa tgtcaaaggc atcttcaatt tctgagatca cttggaaaac atcaagtgag
    26461 tcagcatcta aatcatcaaa ggtagtttct aaggttactt cctctgcgtc cttgccaagc
    26521 tcctcaacga taatttcctg tactttttca aatactgcca ttttatgtct ccttaatata
    26581 aatatttatt ttataaatgt gctaggcaca tgatataact agattttaac aattagactg
    26641 ccccatgtca aacctccacc gaagcccgac agtaaaatat gctggctgcc gtctaattta
    26701 agctgtccat tttggactga ttcagatagc aaaatcggta tactagctgc actggtattg
    26761 ccatagtgca tcatattttc cagaaatttc tctcttggca taccaatttt cttagccatc
    26821 ttatctaaaa tacgccgatt ggcctgatgt aaaagcagat agtctaactc ctccttggcc
    26881 aagcctgatt gctcaataat tgctgtaatg ctccttgaaa catctctaat cgcaaagtca
    26941 aagatagcac gaccatccat ctgaagaaag gagttgacct cctgtccttg agaaaatggt
    27001 gagcgcagac tgctctgacc tgatgtcagg ctttgacctt gcgcaccatc agtatgtaag
    27061 gcctcagcta gaaaatgctg ctgctcgctg gcctctaata aaaccccacc agcaccatct
    27121 ccaaataaaa cagctgtgct tctatcctgc caatcaataa tcttagacag ggtctctgct
    27181 ccaataacca agcctctttg ataagcccct gatgcaatca acttatccgc cattgctaag
    27241 gcaaagacaa agccactgca ggccgctgtc atatcaaaag caaatgcatt agtagcaccg
    27301 atagcagcct gaacctttgc tgccgtcgat ggcatgctag catctgggct aatcgtagca
    27361 acgatgataa aatcaagtgc agtcgcatca tatcctgacc ctgctaacaa ttgctctgct
    27421 acccgaatgg ctaaatcact ggtcatctcc acagtggaaa tgtgacgctt ctcaatccca
    27481 gtccgtgacg aaatccattc gtggctggtg tccatgattt gcgacagatc gtcattacta
    27541 ataacctgct taggcgtata atgagctacc tgactaattt ttgaaaagac cattaaacca
    27601 aatcctccaa aaactgatgt aagttcccca agccacgtaa cagggcttgc atttcgtcct
    27661 cattcatatc agcgatcaca tgaccgacca tatttttatg gaatcttgca tggagacgat
    27721 ccagaagacg cccctttttg gtcagtgaca ggtaaacaac ccgtctatcc acgcttgatc
    27781 ttgttctttc aatatagccc tttagctcta gcttgtttaa gctagtggta accgttccta
    27841 aggtaaccat gagctctctt gcgatgtcac ttggcgttac ctgctgatat tttccaataa
    27901 tctcaattgt gtgcatctcc tttagagaaa catcattaaa ttgacttgtt tttaagctca
    27961 tttcctcaat aaccaaaatt ctgttgaaaa tatcaactaa atattgatta atcttattat
    28021 attccaagta aacacctccc tagctgtaaa atactttgac tatcaaagta tatcagacat
    28081 caaagtattt tgcaagcaca taagagctat ttcccccgaa aatttggccg cctcctatct
    28141 ccataagccc tgacgccctc tttaaagtcc tccttaaagg ccaattcctc ttgaatagca
    28201 agctcttttt gggcataatc ctcccaacct gcaaaaaagc tttgccatac caaagatttc
    28261 atgccggcgt aggaatttga agagccacgc ctcaaacgct ttaacagctg actacaggtc
    28321 ttatcaagct tatctgactc agcagctcga tagacaaatc cgtactcaag ccctttttct
    28381 gctgtgaccc cctcaccggt catcaccaga tgagtcgctc tatttagacc aacggcacgt
    28441 gttaacaaga aaagaccacc agcatctggc gctaagccga cattaacaaa ggcctgaata
    28501 aattttgtct gggtgctagc aatacaaaaa tccaccgcta aggcaatatt aaaggccgca
    28561 ccagccaccg caccatcagc acagaggata accggctttg gcaattgctt gatagcaaag
    28621 gaaatatcct gaaccagctc agcaatccta actagagact gaacatcatc tctttcaaca
    28681 gcattttgca tctcaaccaa gtcaccaccg actgaaaaga ccttgccctt tgccttaatc
    28741 actaaaaagc gcagagaggg gttatcctta accaacctaa tagcctccag aatctcctga
    28801 caggctggaa tgttaaagcc attagacacc tctggacgat ttaaggttaa aatggccaga
    28861 tcctcttcaa gctcaaaaat gatattttga aacgtcatat cactcctctt ttctgacagc
    28921 ttatttgatt accaaataat tttatgacca aataatttga caatcaaatt aattactaga
    28981 ctatagtaca ctagaatcag tcgttatgca agaaaaagat tgtaaaaaat acattaaaat
    29041 tgactgcgca atttaaagca tgcagcccta aaaccaagct cagacctagc ctctatacct
    29101 ctaataaaag agcctaagac aaaagtgtcc tagactctga aactttggca tgtgctatgc
    29161 tcaaccattc tatacaattg tgatcaatcg ctcatagagt gtgtaaacaa gacccgctta
    29221 aatatcctct agagcgtctt tgaccttgtc aaagaaacct tttttctttg gagcaatcgg
    29281 cttttcgcca ctagcctccg caaaagcctt caaggcctcc ttttgagcct cattgagctt
    29341 ggtaggcgtt acaatgttta cagttacatg ctggtctcct tggcctccgc ctcgaagctt
    29401 aggagccccc ttgcccttca agcgaaatac cttaccagtt tgtgttccag cgggaataga
    29461 catggcaaca tcaccatgga ccgttgggat atctactgta tctcccaaag cagcctgaac
    29521 aaatgaaata ttcaagctgt agtaaatagt agagccattg cgctcaaact gtttacttgg
    29581 aagcacgttt aaaataacga acaaatcacc ataaggtcca ccattaaagc ctgcttcccc
    29641 ctgaccctgt aggcggattt gttggccggt ttcaacacct gctgggattt ttactgaaac
    29701 cttatgaacc ttcttttcat gaccagttcc atgacaggta tggcaaggct ctttgatttc
    29761 ttgaccgctg ccatgacaga catcacaggt cacctgacga cgcatcatgc caagtggggt
    29821 ctgcgtatca acattgataa cccctgagcc atgacattta cggcaggttg taggacttgt
    29881 tccaggctta gctcctgagc ctgcacaggt gctacaggtt gattcacgat gatagctgac
    29941 ctctttttcg gtaccaaaaa cagcttcctc aaaagaaagg tttaccctat attgaaggtc
    30001 atcgccctga cgtggagcat tgggattacg cataccacca ccgccaaaaa agcttgagaa
    30061 aatatcctca aagccgccaa agccaccacc atcgaagccg ccaaaaccgc ctgcgccacc
    30121 accaaagcca ccgtttgctc cggctgcccc gtattgatca taggctgcac gcttttgtga
    30181 atcgcttagg gtttcatagg cttcctgtac gtccttatat ttttgctcag ctcccggctc
    30241 tttattgatg tctgggtggt atttcttaga catcttacgg taagctcgtt taatatcatc
    30301 ggccgaagcg tcctttgaga ccccaagacg atcatagtat tccgtattat tcatttattc
    30361 tttccttcat tgacaaaaac agacggagcg aggcgccccg cctatttgat ttttatttat
    30421 ttagccttgc tatgctattt tctagcaatt aggggagggg actatcgcct cagtttctag
    30481 ctttactgag cgaccttagc tcctcacagc ttatttttca gtgaactcac catctacaac
    30541 atcatcgcca ctgtttgttg agcctgtatc tgctgcacct tctgcaccag cctgggcttg
    30601 ttgtgctgcg gctgcttgct cgtacatttt aacagcaagg gcttgtgctt tttcattaag
    30661 cgcttcaagc ttagctttca tatcatcaag gtcgcctgac tcttgagcct tcttaagctc
    30721 atcaagagct gtttgagcag catcacgctc tgtgtcaaag cctttgcctt cagtttcttt
    30781 aatagtcttt tcagttgcaa agatagcctg gtcaacttca tttttaaggt caacctcttc
    30841 cttacgtttt gcatcggctt cagcattggc ttcagcgtct ttcatcatgc gttcaatttc
    30901 ttcttcagaa agaccatcgt tagatttgat gacaatatgt tgttcttttt gagtacctag
    30961 gtcttttgcc ttaacagaaa caataccgtt tttgtcgatg tcaaaggtta cttcgatttg
    31021 tgggatacca cgaggggctg caggaatgtc tgtcaattgg aagcgtccaa gtgttttgtt
    31081 atctgctgcc attgggcgtt caccctgaag cacgtggata tcaacagctg gctggttgtc
    31141 tgctgcagtt gagaagacct gtgatttaga ggttggaatt gttgtgttgc ggtcaataag
    31201 ctttgtaaag acgccaccca ttgtttcgat accaagtgac aatggtgtca cgtcaagaag
    31261 aacaacgtct ttaacatcac cagtgatcac accaccttgg atagcagcac ccatcgctac
    31321 aacttcatca gggttcactg atttgtttgg ctctttgcca gtttcagcct taacagcttc
    31381 aaccacagct gggatacgag ttgaaccacc aacaaggata acctcatcga tttctgacaa
    31441 gctcaagcct gcatcagaca gcgcttggcg aacaggaacc ttcgtacgct ctactaaatc
    31501 acgagtcagg tcatcaaatt ttgcacgaga caggctcatc tctaagtgaa gcggaccagc
    31561 agcgccagca gtgatgaatg gcaatgaaat ttgagtttga gtgacacctg aaaggtcttt
    31621 tttagctttt tcagcagcgt ccttcaagcg ttgaagagcc attttatctt gtgataggtc
    31681 aataccgttt tctttcttga attctgctac taagaaatca atgatttttt ggtcaaagtc
    31741 gtcaccaccg agcttgttgt caccagcagt tgcaagcaca tcaaagacac catcacccaa
    31801 ttcaaggata gacacgtcaa aggtaccacc accaaggtca aagactaaga tcttttcttc
    31861 tttatctgtc ttgtcaagac cgtaagcaag agctgctgca gttggttcgt tgacgatacg
    31921 ttctacctca agcccagcaa tcttacctgc gtccttagta gcttgacgtt gtgcatcgtt
    31981 gaagtaggca ggaactgtga taacagcctt tgttaccttt tcaccaaggt agtcctctgc
    32041 atagccttta aggtattgaa gaatcattgc tgagatttct tgtggtgtgt attctttacc
    32101 attagcagca accttttcag aggttcccat ctttgatttg attgagataa cagtgtcagg
    32161 gtttgtcact gcttgacgct tggcagcgtc accgacaatg atttcaccgt ttttaaatga
    32221 cactactgaa ggggttgtgc ggttgccttc tgggttggca atgattttgc tttctgttcc
    32281 ttcaagaact gctactgctg agtttgttgt tcctaagtca ataccgataa ttttagacat
    32341 aatatttttt cctcttttat atatttatga tactcctctt atgtggcacg gacgctagca
    32401 gcttcctatg gaatctcata gctgaaattt gagcctaaag tctcaaattt tccgagtcat
    32461 aaaacactag tgttttatga cttttgccac ggcgaagagt atcggtaatg ctcacttcgt
    32521 tcgcttttgc tagcgcaaaa agcagcaatc ttatttctta ttttcatagt ttaccgtcat
    32581 ttcggacatg attcatttta ttgattagct atcatcacgg gataattgcg acgtgagata
    32641 gcaaaatcga taccattttg ctatcgagct agtaaggagt ctaggcaagc cgccacagcg
    32701 gttgccgtct aatgacgagc catttcaatg gccatcatta gtgactagtt gtacacaacc
    32761 accatcgctg gtcttagtaa gcgctcatga agcttatagc ctttttggaa aacctgagcg
    32821 atactatctg ctgggtggtc atcatctgct ggtagggttt ggactgccat gtgcagattg
    32881 tggtcaaagg cttccacagg aacctcttca ataccttctt ctttaagggc ttgaacaagg
    32941 ctttcttgca ccatttctag gccttttttg acatcatctg tcagaccctc aacagccaaa
    33001 gcacgctcca agttatctaa gcttggaagg atttttttag ctaaatcctg tgaacgatag
    33061 cgctgcaagc tttggcgttc ttcattcgca cgacgctgaa tattttgcat ttctgcgtga
    33121 gctctgaggt atttattttc aaaatcttct gctcgctgga gagccaactc tagctcagat
    33181 ggttcctcgg ctgcttcatc agcaataagc tcagctgatt gatcagcttc ttcaactggc
    33241 tctactgctt cctcagcagc ctcatcaaga atgtcctctt gatccttgag ctcttctttt
    33301 ggttttttag acaaggtgtc tacccctttc ttacattttc ttaaatcata ttaaggcctt
    33361 agtgaacctc ataatggttg ctgtttaagt aacggtaata atctcttagc ttcacagcca
    33421 gtagctgacc aatcacatta atcaagctaa cactacgacg ataatccata tcaactggcc
    33481 caattaagct taagaggcca aatcctctgt atggaattaa aaacttgtag gtcagcaagg
    33541 tcacgtttgc tagggctggc tcactgctgt cagcaacctg aaccgttgcc atctcttcct
    33601 ctgatagact ctgtctgata gatagggcta agcgctgctc ctcatcaaga aactgatagg
    33661 tcgcaagacc agcatagtca agggcagcaa ccttgccaga gacaaaaatc gtttctcgaa
    33721 aaagcccgac aaagatataa tcaaacaaat ccaaaacatt gtctgtcacc gtaaaatact
    33781 tctgaacaat ctgagggatt tcggttcgca gcttgtaatg aacagtcata acatctttgc
    33841 caagtaagcg atcagcaaca atgcccttaa gcaccagcaa atcacgattc ataaaattct
    33901 taggaatggc aaactgtacg gtcaacggct tggactcatc taagctcaaa actgccaagg
    33961 catcatgact agatagctga acaatatcaa agcctgtcag cctttgcctt gcaggctcaa
    34021 catctaaaat cgccgccgta tagccggtcg tatccgatag catctggctg gctcttagca
    34081 aaacgtcctc cagcttaaag gcctcaaaat caaaggcctt gaccagctga taaaggtcct
    34141 gctcatcaat gctgccaaga ttaagagaat gctctacaaa atatttaaag cctgccgcac
    34201 ttggcatgcg cccacttgat gtgtgagcct tctccagcaa tcctagtttt tcaagctttg
    34261 ccatgtcatt tctaatagtg gcactactag aagcaataag tgactgcaaa gccttagagc
    34321 caactggttc atgggtctgt gtaaataaat ctacaataag attcaaaata ttagattgtc
    34381 tctctgtgat cacaaaccaa tcactccctt tctgttagca ctctatacat cggactgcta
    34441 atttataatt ctattatatc cttttaaact agcatgtcaa gaaaaaaact caaaaaatta
    34501 gcactctttt tttagagtgc taatttttat aaaacattga cagtgttgcc tttgacatta
    34561 tgcttgaaag aagtaataga gagccactta ctacctctca gactggtatt ggcttctccc
    34621 gactcgctag ctaaaaggag cgctaagctg taagggggat tagcttaact gcctgaagcc
    34681 ttaaggccta acaatcaagc ctttagtaga gcaggataaa tcaggctgcg tgctcacagc
    34741 tcctactctt aaggcttaca ccttcaagct gatagaaagt tgcaatacct actaaagcaa
    34801 atacctgagc ttaccggttg tttcggtgtc tttttcatct cctcaatcat catagcttgt
    34861 caaacctctt gcttcaatca gctgcacaag cctttgggca tagcccttat catcagaata
    34921 gcgataggtc tgcagacttt tagcaggttt tttataccct ttttcggttg ctaggctttg
    34981 gtaaagcttt ttctcctcgc ctgtgccttg actaagccat gataagtaag ctctgataga
    35041 gtcctctctg tcccgataga tagcataggc tgtcttgtgc tttgaggctg cttgcttctt
    35101 gaggctaatg gaagcctgcc ctggagctgg ctgcagtgaa aaaaggttgt ggtatttggc
    35161 cgccaacagg gttctgccat aattggtttc taaaataatc tgaccaatca aaatagaagg
    35221 acgaatgcca tagtttttgg ccaatggctt gacctcctta gcaaccaact ggataaattg
    35281 cctctctgta tagggaacag acatctcctg actggccgat gtgcctttgg cattgaacag
    35341 caagggacca atcaaagcca ccataatgaa cactaaaaac actagaaaat aggaaaattt
    35401 aagtcgtttt ctcatttttt ctccttcaat cgtgttaggt attcttctag gctgaggcta
    35461 tgagcggtaa tgtatagggc agaggcttta ccaacatagc gataatgcca gtcctcatac
    35521 tcaatccctg tgctagtctg cttccctttt ggatagcgca aaataaaacc aaattgtgga
    35581 gctatttttt gaatctcctg tgccacctta ggatcactag cgtttaagtt atctactgtg
    35641 ctcatatcaa tggctagacc agtctgatgt tcactagtgc ctgctggctg ggcatatttc
    35701 cgaaccaagg cttcagctgc ctcttgggtc aggctaggat catttgccag ctcttgggca
    35761 atataagact gataaagctc ttcttgctgg acaaccgaac gataaccagc aatcaagtgc
    35821 tcctgaggtt caatcgtctg cgccgctgct agaaaatcag ccgtctcctg ctcaatgcgc
    35881 ttatcaatag gaatcccatt aatctcaacc aactcaggac tcatttcctc ttgagggtga
    35941 tcgcgattga caaggaccag ctgccagtcc gtagttgata cctttggcag atcagtagtc
    36001 tttttagcct gcttagctgc ctttggggca ggtactgttt gattagcctt ggggcctaca
    36061 gcctgttttt caggcttgat aaagaggtaa acccctgata aaaacaacag gacgaccaag
    36121 gcctgtaaaa ggactcttat agtgttattc ttcatctctt attgactcaa ttatctcacg
    36181 accacgatag cggtagctca tatctccaat cgttttgatg gtaaactgcc cattctcata
    36241 ttccacaaca gtgacgcttc cattgtcaat gtattgcttt tccctatctg ggtcaattag
    36301 ccacataaag gttccaatgg tcatgccatg actaaccacg atagcattgc cacctcctgc
    36361 attttcaaca gcaagcgcga tagcctcaaa gccctcatag atacgcttgc tcaatacctc
    36421 ccagggctct gcccagttag cagtatcaac ctcgacaata ctctctgcta attctgaata
    36481 aggcacatca cgcagattgt cacgattttc aaaggccttt gttctaggta aaacacctaa
    36541 aaacagctcg gaatcataag ccccatctag actaccaaag caccactcac gaatccgctt
    36601 atctctagtg tagggtaaaa actcattttc agactttcgt agaataatct ccattgtctg
    36661 catggtacga cctgaatcac tcgaaaaagc agccttgaat ggaataccag cagccttcaa
    36721 accaagtccc aattcacgaa tcccttcttc tcctgccttt gtcaaggggg tatcactcca
    36781 accctgtgca cgaccaatgg tgttgaacat cgtcttgcca tgtctgacaa tgtataatct
    36841 tgtttttgtc ataatgaacc tccaaagtct ctctgctatt atagcattaa aagaaaacac
    36901 ttgcaaaacc atgcaagtgc tagccgttaa ttcttaaagc tatggatagg agctggtatc
    36961 tgcccaccac gagcaataaa gtcagccgat gaatgcggat taacagccat aaccggagct
    37021 gtccctaaaa gaccaccaaa agcaatcata tcaccctcct taccctttgg aataatacga
    37081 acagctgttg tcttttgatt aatcaccccg atagctgcct catcagcaat catggctgca
    37141 atggtttcag acggtgtctc ctctgggatc gcaatcatat ccaaaccaac cgagcaaatg
    37201 gcagtcatgg cttctagctt ttcaagatta agcgagcctc cctgcactgc tgcaatcatg
    37261 ccctcgtcct ctgatacagg gataaaggca cctgacaacc cacccactcg gttgcaagcc
    37321 atgacaccac cctttttgac tgcgtcatta agtaaagcta gggcagctgt cgtgccatgt
    37381 gtgccaacta tttcaagtcc catctcctct aagacacgtg ccacagagtc accaactgct
    37441 ggagtgggag ctagcgacag atccacaaca ccaaagccca cacctagccg ctcacttgcc
    37501 atctgtccca ctagctgacc gatacgcgtg attttaaagg ccgttttttt gacggtctcg
    37561 gctagaacgt caaagctttc accacgaacc ttttccaagg ctcttttgac cacaccaggt
    37621 cctgaaacac caacgttaat caccgtatcc gcctcaccga caccatgaaa ggctcctgcc
    37681 ataaaaggat tgtcctcaac agcattagca aagactacta gctttgctgc ccctatctca
    37741 gaggctttgg cggtttcctt gatgatacgc cccatgtctg caactgctgt catattaata
    37801 ccagaccttg ttgatccaac attgaccgaa gcgcagacct tctgtgtttg agccaaagcc
    37861 tgaggaatag actcaatcaa aatcttatca cccttttgat agcctttttg cacaagagct
    37921 gaaaagccac cgataaagtc aactccgata tcacaggcag cctgatccag agcttttgca
    37981 agcgacaggt agtcttctgc gtctgttgcc gccccaataa gggctatcgg agttacagag
    38041 acgcgcttat taacaatggg aatacctagt tctgctgcaa tgtcatcacc aaccgccaca
    38101 agattagctg cctttgtcgt aatcttttgg taaatcttag cggcagctct atcaatatcc
    38161 gaatcaatac aatccagcaa ggaaattccc atcgtaatgg tacgaatatc aaaatgctgc
    38221 tcctcaatca tctcaactgt ttcacgaacc tgtctaatat ccatagtcat caagctcctt
    38281 atatgttatg catagcatca aaaatcgctg cgctttgaat attaatcgtc acctgcaatt
    38341 gctttccata agcctgaagc acctcacgca gatgagcaaa atcctgcttt tcactgcttg
    38401 agacaatggc catcatggta aaataatcat ctaaaacggt ctgtgaaatg tcatcaatat
    38461 ttaaccctaa tgcagcaatt tgtcctgaaa cacctgcgac aatcccttga ttgtccttac
    38521 caacaactgt aatgatagct ttcatggcac acctcctcaa tatgtgttat attttatcac
    38581 aaacaaaaag agaaagctat cagagacaag aggtctggta gccccttgca aaaatagaac
    38641 aatgggtacc agaaaaaaga gtttgttatc caattgatac cgtttattaa tatttagact
    38701 ttataatata atagcagcta ataaaagata agacgtttga agctgccaaa aaagctgggt
    38761 ctaaggaagc ccagcttttt tgtaggttaa ttaagggata gcagaagatt agtcgggatt
    38821 gtaagaatag ccgtatcctc tcttaccacc tctatcagct agaccatcta aatagccatt
    38881 tccataatta tcattatacc cttgactata gtcattatat tcctttggac tagactcatc
    38941 aaaccgctta ggataatctc ctttgtgctt tttgccacca tatccatcct catagccaac
    39001 tcggtaacca tcacgacgac catgattgta ggggtgttcg tctttaagtt ttggtgattc
    39061 atcattttct ccgcttaagc ctttaccgtc taaatcttcc tttggcttat tctctccatc
    39121 taatcctttt aaaggatttt tacgattatt tccttctaaa ttcggagttg atgggggacc
    39181 ggcttcacct cgttcacctt gctctggttc cttctgattc tcaccattca agcctggaag
    39241 cgaaggacgg ccttgattat taccactcaa ccctgaaagt gggggaccag cctcacctcg
    39301 ttcaccttgc tccggttcct tctgattttc accattcaag cctttttctg gcagcttggg
    39361 actattgccc tgaggctttg gttgaggctg cgggctagaa ttatccttac ctagatctaa
    39421 gtgctgtggc tttccttgtg gctgatggtg atgacctgaa ccagagctgt tacctcctct
    39481 cagccccagt ggctgggaag gcccttgatt aggaatagcc tgaggctctg aggcctgtcc
    39541 actactattt ccttggctgt tcacactgag agactgaggt tgattcccat gatgacctga
    39601 gctctttgct gtcggctggg acgggctagt agcctgatgc tgatgattag taggctgatc
    39661 tgaaggctta ggctgcaagt tatccttttt cggtggccga ctgaccattg aatctgatga
    39721 gctcttgtgc gacttatcgt catctccaat cgagctgact ggctgctcct ttggcctcgc
    39781 ttgatgggat gagccaccaa gacttcctaa taaacctcca aagacaagtg cagctcccag
    39841 cagcaagctg gtcaccactg caccggcaaa tagccattgt tttttggact tccatgtgcg
    39901 aaaacgtcct tctgtttttc tcatactttt ttaactctct ccatattttt tggtaaaaat
    39961 accaagaaat agtatatata gtcaagactt tatcatattt cttttaaatt tttatcatct
    40021 gatatattcg attgttttta caaatctgat aaccaaaaaa tcctcgtatc atactgatac
    40081 aaggattttt atatatttga acgtcacaag tactcctggc ttattgtttt ttgccaaaga
    40141 gcgctgaagc aacaattatc acaatagctg ctcctagaat tgaagggaaa acagccatgc
    40201 ctgccagctg aataccccag tcgccaaaca gcttttgacc aactgcagag cctatcaaac
    40261 cagcagcagt cattgtgaaa cagcccatcg aatggctttt ttctgttatc ctacctgcaa
    40321 ccatgccgat aatagctcca acaattaatg accaaaccat cgcaaatctc ctttatgttt
    40381 tgtcttatta taccataccc ttgccttata tcagtcagat gatggtggtc gcttgatatt
    40441 aagagcaagc tgcttttttc tcttagtaag caataagtct ctcagcgata tcacaagcac
    40501 tgctattaaa atcaaggcca ttcctaacag atcaataggg tgaaaaatct ctttcatcag
    40561 gataatcgca aagcagacag aggcaaccgg ctcaattgaa gccagcaagg tagccttgat
    40621 cggtccaatg attgaagccc cctttagaaa aaaggtgtag gcaaaaattg tcccaatacc
    40681 gataatgcca aacagggccc gtagattccc ataagtcatt gccaatgggt actgccatgc
    40741 tcttgtcagg atcggaaaaa tcactcctcc catcagcatg gcaagaccaa caatcagcaa
    40801 gctcccccag tcggcaatca gcttagcagg cttgatgaca cagtaagcat aggtcaccgc
    40861 tgcaaaaagc ccccagaaaa gtccaatagg attgattgcc agatgggaaa gatcaccatg
    40921 acaggccatg ataaccgttc ctaggatcgc taggcaaata gcacagctct ctcccacagc
    40981 cggcaggcgt cttgatttga acgataggta gaccagcacc aaaatggggg aaaggtattg
    41041 caggactgtg gctgtaccag cattagagta acgaatagca agcagatagg catattgatt
    41101 aagtgtgaga ccaaatagac tgtaaatcaa cagctctctt aaaagccttt tgtccttgag
    41161 taagctgatg acagcctctc tttgccgcac ataagccata gctgacagca caagccctga
    41221 aataatgagc cttagtgagg tcaaggcatt gatgccgacc ccatgagcaa ttaaatattg
    41281 ccctgacacc cctgagagac cccaggcgat tccggctagt aaaatcatgg tactgccttt
    41341 tccatttctt gacatattat cttcctcttt ttaatccatg ccatgataag gccactcata
    41401 ataccttgat agctctagcc tagacttcac caagcctgct taacagtcat taacaacaga
    41461 ccgataagct acctcttaca gcttcggata gcgaggtatt atcacagaat tgtcctaaag
    41521 agcctaccat cataaagagc ctgaaaactc tgtttcagac tcaatgccag tcataacgac
    41581 tccttaatcc agcaattttt gcaattcttg ggctaacaat tgctgagcta tctgtgggtt
    41641 ggcttgcccc tttgtggcct tcatcagaaa accagtaaag gccttgtcag cattgcgctt
    41701 gcctgatttg aaatctgcca cagcagcctc attgtcagca aacacctgat gaatgattgg
    41761 aatcaagaca gctgggtctg aaatttgaac caagccggcc ttttccacat aagcacgcgc
    41821 tgagccgcca tgctttgcca aatgaacaaa aaccttcttg gcgatttttg atgaaatcgt
    41881 gccatcagtg atgatcgcaa tcatttccac gagattttct ggggtcaagg caatctgatc
    41941 aatcgtcttg ccctcagcat ttaagaattg agccatctca ccctgaagcc aattagacac
    42001 ctgcttagga tcaccaccaa gtgccacagc ctgctcaaag aaatcagaca aagcctttgt
    42061 tgctgtcagc tgacctgcat cataggctga caagccaaga gcattaatgt agctagctcg
    42121 cctgtctgcc ggaaatcttg gaagctctgc acgcatatcc tcaatccatg cgtcatcaat
    42181 ctcaaacaat ggcaaatctg gctctgggaa atagcggtag tctgctgctc cctccttgac
    42241 acgcatgaga atcgttccct tacttgcctc gtcataacga cgtgtctcct gacgaataac
    42301 accgccagag cgtaggattt tggcttgacg ctccacctca aactcaagcc ccttacgcac
    42361 attgctaaat gagttcaggt ttttcaattc tgtttttgta ccaaaggcct cttgtccgta
    42421 tggtcgcaag gagatattgg cgtccacacg catggacccc tcttccatct tgacatcaga
    42481 aataccagta tactgaatga tttcctttag ggcagtcagg taagcatagg cctcctctgg
    42541 agagcgcatg tcagcctctg agacgatctc aatcaagggc actccctgac gattgaggtc
    42601 aacataggaa taaccatctg taccatgcgt atttttgccg gcatcctctt ctaggtgagc
    42661 acgctcaata cggattttct tggttgagcc gtcctcaaga gtaatatcaa tccagccatt
    42721 gtagccaatc ggctcatcaa actgtgaaat ctgataggcc ttgggattgt ctgggtagaa
    42781 ataattctta cggtcaaagt gcatgtgctg atgaatagac atgttaagag caagtgctgc
    42841 tttgattccc gcatcaatga ctcccttgtt catcactgga aggacacctg ggaaagacca
    42901 gtcaatcaca ttagtgctgg catttggatc ctctccaaaa tgagctgatg aaggtgagaa
    42961 aatcttagaa ttggtattca actccacatg gacctcaagt ccaataatgg tttcaaaatt
    43021 cattacctgt cacctccaaa aatcataggc tgctgcttgt ggtagtcagt agtcgcttca
    43081 aaggctaccg ctacctgata gatgacctct tcgctatatt ttggaccgat caattgaagc
    43141 ccaacaggca agccatctgc aaagcctgct ggaatagaga ttgcaggcaa gcccgctaga
    43201 ttcaccggaa tggtcaaaag atcagccaaa tacatggcaa caggatcatg attcaacgta
    43261 tcaagctcaa aggctgctgt tggtgctgtt ggtcctaaaa tcaagtcata atcagcaaaa
    43321 accttctcaa agtcttgaat gatcagcgtc cgaacctgac ctgccttttt gaaataagca
    43381 tcgtaatagc ctgatgataa gctaaaggta ccaagcatga tacgacgctt aacctcatca
    43441 ccaaagccct gactacgcgt cttgacatag atgtcctcaa ggctcttggc atcagcagca
    43501 cgaaagccat agcgaatacc atcaaagcgc tgtaggtttg atgaggcctc agatgaagcg
    43561 atgatataat agacagccac cccatacttg ctatgtggca gactgacctc ctcaatgata
    43621 gctcctagct tctcaaaatg cttagcagca gccaaaaccg tctccttaat cttaggatca
    43681 atgccttcgc caaggtattc cttaggtagt gcaatcttca tgcccttgat gtcttgaccg
    43741 atcttaattg tgtagtcagc gatctgtaca ggtgctgagg ttgagtcctt gcggtcactc
    43801 cctgcaatga ccgatagcag ctgggcattt tctcttaccg ttggcgcaaa aggccctatc
    43861 tgatctagcg agctgccaaa ggcaatcaag ccatagcgag aaacagcccc ataggtcggc
    43921 ttaagcccaa caacaccatt aaaggctgct ggctgacgaa tagagccgcc agtgtctgag
    43981 ccaagagata agcgaacctg acctgaagct actgctgttg cagagccacc tgatgaacca
    44041 ccaggaaccc tgctatgatc ccaagcgttt ttggttttct tgaaataaga cgtttctgtt
    44101 gagccaccca tagcaaactc gtccatattg gtcttaccaa taacaatcat atccttgtcg
    44161 taggcattag ctaccgctgt cgcatcaaaa atcggctcat aattataaag catcttagaa
    44221 gcagcagttg tcagaatccc cttggttgag atattgtcct tgacagctag tggtattcct
    44281 gacatcacat tgtcaggatc aatcccctta gcatcaagtg cagcagcctg ctttaaagca
    44341 gcctcgcaag caatggtaat gaaagaaccc acagcctcct cacgcgcctt gatatcctca
    44401 agggttgcct ttgttagctc aactgcagaa atgtcctttg caacaagaag ctcatgtaat
    44461 tcttctatag tatgatgatt aaaagacatt aggcatctcc tccgtcatca agaatagctg
    44521 gtaccttgat gaaatgattt tctttttcag gaacattttg aaacaggagc ttgcgatcca
    44581 ctccagcctc agcgatatca gctcgcatga tatttttctt gtctgccatt gtggtggtaa
    44641 tggcaacacc tgtcgtatcc acttcattta gcaattcaac catgtcaacg atttttgata
    44701 atgttgtcgc aaactcagtt gtttcacttt ctgaaaagga tagctttgat agggccgcaa
    44761 cgtggcgaac ctcttcttca gaaattttca tgaattctcc tatccaaggt aaagcagacc
    44821 atcatcagcc acaaggcctt gctgtttcaa acgcttgata atagcctgaa taacccaatt
    44881 ttacatagtc ttaaccatta tatcataatt agctttattt accatagcgg actgctggga
    44941 tttcacgtca aatgcatgtg gcaactgacg ttttctgata acgtttttca taagctcaac
    45001 ctgctttttt caagaacagc caggctataa ctaaactgca tttgagcaat tgatgaggtt
    45061 aaaagggcaa tgtggctaga gcatagctac ctgcatttta ttcacgtgta tgcgtagctg
    45121 ggattagcga aaaacttaat aacaaaaagc ctcctagcca agaccaaaag atctcactaa
    45181 gaagccctta agatcagcgc tgagccaagc agcagctaat actgccttac ttgattagcc
    45241 tatcccagct gatcgaacga tcgcctaaga aagccgatca agaagctttg ctcctaggac
    45301 agtcctacag tggttcagcg cccactggtg attttctgtt gaattgctcg ccactgctga
    45361 tgtgataatc tcaagcttgt agcccaattt ataggcatca atcgctgtat gaaggacaca
    45421 aatatccgtc agcacacctg tcaagaccag cgtcgtgacg ccacgctcac gaagacgaat
    45481 atccaaatca gtccccgaaa aggcagaata atgccgctta tccagccaaa agacccgctg
    45541 atcttgctgg tatctggtat atacggtcat caaaggacca tacaggtccc gaccccttgt
    45601 cccgataata ttatgcggcg gaaacaaggc tgcctccgga tgaaagctat ctccctcctc
    45661 gtgggcatca atcgcaaaaa agatatagta gccggcctca aaggcagcct caacaacgct
    45721 agccatcgcc tctgaaatca cctgagcagg tgctcctgcc gtcaggctac catcatcagc
    45781 tacaaagtca ttcgtgtaat caatagaaat caaggccttc acagcttatc cctccccaaa
    45841 aagcttatgc tctcttagct gcatgacagc aagccataag aactaagcct gcttttaata
    45901 ttcagtatga ttagacactt atagtttacc actaaacacg acagctgtca agacagcgga
    45961 ttgatttata cacgataaag gcgaaaaaca gttatttctg aactatagta tagatttaag
    46021 tagacacttt caacgttttt ctatatgaaa ataagatata ttcctgaaat agctgaacat
    46081 tgaaatacag aaagccttat tttcttgcta aaaatctttc atgcatctgt catgttcatc
    46141 tcatgctgaa tcacagcgaa aatacaaaaa atacccctca aaagccagcc aatgctagaa
    46201 cctttgaggg gacgctataa taatgtgtga agtcctccac agctgctaag aaactccgat
    46261 aagccgtcat aaagaccaag tctagccctt accaagcagg gctctggcta atgaatggct
    46321 gctctataag cagcaagact ttgatcatag ctaacacttt cactacctgc tctgactaat
    46381 cacagctagc aaagctaaag gcaagccttg ggcttagcag acgatcgcat ctgagctatt
    46441 aaaattcctt tagcttgtca aagatgcctt cgttaatcac cttgagataa gtgcctttca
    46501 ttcctagaga gcgactctca atgatacctg cactctctag ctttctaagg gcattcacga
    46561 tgacagatcg tgtgattcca atacgatctg caatcactga agcggtcagg cgtccttcat
    46621 tgccatctag ctcactaagg atagctgcaa cagccttcat ttcagagtaa gatagagtgt
    46681 tgattgccat attaacaact gtctgcttac gaatggtttc ttctaggttt tctgtttgaa
    46741 gatttaacag ctgaataccg accacagtgc ttgagatttc aactaaaaca aggtcatcat
    46801 cactgaattc attgtcgtta cgccagatga tcaaggtacc taagcgcatg ccgccaccat
    46861 agataggggc aatcgtggtt aaaccatcag gatagatatc ctttgactca ataggaaaaa
    46921 tcgttagttc attttccaca gaaaggtttg cttcagtgtc ataaacacga ctagctgcct
    46981 tgacataagc atctgggaac tgtcttgttt caaaaaattc ctcgacgcgg tctgtgttgg
    47041 tcttgtactt catcgcatag ccaagtaagc tgccgccacc attgatgata caagcattac
    47101 aatcaataat atctgctaag cgtgaagcca tagtgttata ggggagttct gtttccaagc
    47161 tgtctacaga acgttgcaaa atagaagtaa tcttacgggt tttttctaat aaatttggca
    47221 ttttttcttt tccttttaat tatttgcgtt acaattatat caaaggaccc tagcttttgc
    47281 aaggaattat cagaaaattg gctattatac ctacaattcg gatgaggcca gagccttatt
    47341 ttgctgaaaa acaaaaagga tctcgcgatc caatttttgt atgagaatca tattagcgct
    47401 tgtattgctt gagaacatgc gtgatctttt cttgcacgtc agctagctct tctactgttg
    47461 gcagatagac cacgcgaaaa tgatcaggct ccttccagtt gaagccacgc ccatgtacca
    47521 gcatgacctt ttcttgcttc aaaagctgta ggacaaattc ctcgtcgtca tcaatgcggt
    47581 acatatttcg atcaattttc ggaaacaaat agaggcctgc cttaggcttt acagctgata
    47641 ggcctggaat ggcattaatg gcctggtaaa tgaagttacg ttgctcaaag atgcgaccac
    47701 ccggaagcaa gagctcatca acagactgac gtcctcctaa ggaggtctgc accacctgct
    47761 gcgctaagac attggagcac aagcgcatgt ttgccagcat gttcaagcct tcaatgtaac
    47821 ctctgacatg tcttttaggg cctgacaaga ccatccagcc cactcgaaag ccggcaatac
    47881 ggtgtgattt tgacagccca ttcattgaca cgcaaaaaac atcaggtgca aggctggcaa
    47941 ttgcgatatg ctccccaccg tccatgacca aacgatcata aatctcatct gcaaaaatga
    48001 taagctgatg ctctctggca attgcaacaa tctcctctaa gacctctcga gggtagagag
    48061 cacctgttgg gttattggga ttgataatga cgatagcttt tgtgcgctca gtgatcttgg
    48121 cttttatgtc agcaatatca ggataccatt cagcctcttc atcacacagg taatgcaccg
    48181 catgcccacc acctaggctg acacaggctg tccaaagggg atagtcaggc attggcacca
    48241 gcacctcatc accattatcg agcaaggctt gaagagacat cgaaatcagc tctgagacac
    48301 catttcccaa ataaatatca tcaatgtcaa catcaggaaa gccctttagc tgacaatatt
    48361 gcatgatggc cttacgagct gaaaaaatcc ccttgctatc agaatagccc tcgctggagc
    48421 gagcattgag aatcaaatca cgaataacct catctggagc ctcaaagcca aaggctgctg
    48481 ggttacctgt atttaatcga aggatctttt caccattagc tatcatacga ttagcctcgt
    48541 ccaggactgg acctcgaata tcgtaggcta cgtgttctaa ttttgatgat ttttcaatta
    48601 ttttcatagt ctcattacct cgtaacccat attataaacc aaaacaatta aaatagaaag
    48661 cacttttcta tgagcttaaa gaatgccaaa agctcaacca aagctctaag caagctaagc
    48721 agcagctatt aataaggcta tctaagctag cttctagctc aaggtatcct cacctcaggg
    48781 aatagctggg ctatttggtg aacaatagct cagaaaatca ttaaaacgtt ttcaatttct
    48841 cctcaaaaaa ggtataatag ctatagagat aaagttcaaa ggaggataaa ccgatgtcac
    48901 aaacatatga acgtatcatg gtcgctattg atggctctca tggctccgaa ttagcctttc
    48961 acaagggggt taatgtcgct ttgcgtaatg gtgctgcctt gattttgacc catgttgttg
    49021 atacacgtgc gctgcaaagc gttgcaacct ttgatagcta catttatgac aagttggagc
    49081 aggaagctaa agaggtcttg ggggattttg aaaaacaagc acgcgaggca gggctgactg
    49141 aggtcaagca ggtgattgaa tttggcaatc ccaaaacgct attagcgcac gatatccctg
    49201 acaaagaaga ggttgatttg attatggttg gggcaactgg gcttaacacc tttgagcggt
    49261 tgctgattgg atcatcatct gaatatatcc ttcgtcatgc caaggttgac ctattagtgg
    49321 ttcgagagca tgacaaaacc ctgtagcaag acgaattctc tcagctgtca gaagcatttg
    49381 cagcctaagt gaagtaacca tacctagccc ttagcctcag ctcacaaggc tactaaagga
    49441 ctactgctct catatactaa ttaccactag ctagacttaa gggccctttt attgagggtg
    49501 tctagtctac atcaaaaagc accctgagct aataagtgaa gtgaccccaa gtgttaggcc
    49561 aaatgcttaa cagctaggag atcaactcac agctcaaggt gctttttaat gcctctaaaa
    49621 taaagacagc cttatttttc caagcgctgc aatgattttt gaagctgctt gtccaactct
    49681 tttttgatgg ctgactctgg tgcatagcgc tcctgccagt catctggctt ttgaatttta
    49741 tgcgttatgg gatcaaaatg cgctttccca tcagggaaaa ttttccccat attggcttca
    49801 tggacggtct caaaaatggg ctgagggtcc actcccatca atacaaatga gccataggta
    49861 aaataaagca gatctgtcaa agcatcaacc tgcccaacca ggggtgactc tgggtgctcc
    49921 ttggcctgca ccttcttagc tgccttatca agggcagcat ggaggtctat caaagcctga
    49981 gaaaagcgat gcttatcccc ttgactggct gcataaagaa attccacaag ttcctctacc
    50041 ttaaaatctg ctcgatagcc agcctccttt aaggaatagc ctcttggtgt ttcaatcgtg
    50101 tctccgtcca tcaggcggtg gaaatccttg accttgttga aattatcatc gcgactttta
    50161 aagctttttt ccacatcaaa atgaatcaag ccataatgcg ccagcgcctt agagatacca
    50221 tcattgttat ttgaagctgt tgtaaagtga gcaccgcttt taaccactgc ctcagcattt
    50281 cccatcgcaa caccaacacc aacgcctgag agcatttcta agtcattatc agagtcgcca
    50341 aaggccatga cctctgagag ctcaaagcca aacatctcgc ccaagcgttc aatgcccttg
    50401 attttagact gcccgctaga aatcaaatct aaggaataag ggctgcttct ggttaccttg
    50461 atatgcggga atctttcctt gattttttgg gtgtcatcaa cagaagcaac caagacaatc
    50521 tgataaatcg gctctctcat aatggtaaca agattgctga agctttgcgg cttaaagcgt
    50581 ctgatgaggt ttttaaagct gccctcaacc gtcttgacca gactccttgg cacaatactg
    50641 ctaaccatct gaccaaatgg actggttccc atatcaatga tccgagaccc agcaagacct
    50701 gaagctgttc ctaaggagat ctcgcgcttt ttatcgctag catagcgaat gattttataa
    50761 atggttgact ttggcagctg gttctgatac aagaccttgt ctcgtgtcaa aatgtattga
    50821 ccattgtagg tcactgcaaa atccaagcca aaattttcta aaaagggctg cacaaaagca
    50881 ggtccacgac cagttgccag cccaaccata ataccttgtt tttttaattg ctgaatagcc
    50941 ctttgcgtcg ttttttgaac attttttcga tcattaagca gggttccatc aatgtcgaaa
    51001 aagactgctt ttattgtcaa atccttctgt tctctcttct atttgtgata aaataaatta
    51061 tatcataaat tgaaagaagt atgagtatca aatgaaggaa atcctcgtct tacataccgg
    51121 cggcaccatt tcaatgcagg ctgatgaagc aggcaaggtg agcccaaatc aaaacaatcc
    51181 aatgaatcag gttggcctta gcctggagca tatccaccta actgttgtgg attttttaaa
    51241 tctgccaagc ccgcacatca cccctcacca catgctcaag atgtatcatt acattcaaca
    51301 aagggctagt cagtttgatg cagtggtcat cacacatggt acagatacct tagaagagac
    51361 tgcttatttt ctagacacaa tggtgctgcc tgtagagttg cctattgtta tcacaggtgc
    51421 tatgcgctcg gccaacgaga ttggaagcga tggtatctat aactacctaa cagcgcttag
    51481 ggtagccagc catgagaaag ccaagggcaa gggggtgctg gttgtgatga atgatgaaat
    51541 tcatgccgct aagtatgtca ccaaaacgca taccaccaat gtttcgacct ttcaaacacc
    51601 gactcatggc cctttgggag tcgtcatgaa ggacgattta ctgttcttta agactgctga
    51661 gccaagggtt cgctttgagc ttcgtcatat ttctggcaca gttccgatta tcaaggccta
    51721 tgctggtatg ggagatggaa gtattttaag ccttttgaca cctgatagga ttcagggact
    51781 agtgattgag gccctcggcg ctggaaatgt tcctccccta gcagtatctg agctcgaaaa
    51841 attaatcgcc tctgggattc ctgttgtctt ggtctcgcgc tgcttcaatg gcatagcaga
    51901 gccagtttat gcttatcgcg gaggtggtgc cagcttaaaa agggctggtg ttatgtttgt
    51961 caaggagcta aatgccccta aggccaggtt aaaattgctc atcgccctca acgctgggct
    52021 tacaggtcaa gagctgaagg attatatcga aggctaagct ctcctataat cacaggctac
    52081 tactcctcat ctatagcaca aaaagcacga ctcggtcagc taagaacctc ttgtcgtgtt
    52141 tttatattag ctctgtccag caagtcagcc tcacatctaa tcaaactgat cagcgacacg
    52201 aagattagcc aaaatcggag cccatctagg gtccagctgc caatccttag ctgcaacaat
    52261 ctcagcagcg actcgtcttg cctcctctag gatatgataa tcctctacaa tatcagctgt
    52321 tttgaactct ggcaaacctg attgacgggt cccaaaaatc tctcctgagc cacgcagctt
    52381 gaggtcagcc tctgccagca caaagccatc attagtcgtt gtcatgatgg tcatacgctc
    52441 cttgcctgag tctgtcttag gatctgccac caaaatagca taggattgct tgctgcctcg
    52501 cccaacacga ccacgcaact gatgcaattg gctaaggcca aagcggtcag cattcatgat
    52561 cagcatgatg gtggcatttg gcacattgac accaacctca ataacggttg ttgacaccaa
    52621 gacatcaatc tccttagcct taaagcgctg catgatcatc tccttgtcgt ctgccttcat
    52681 tttgccatgc atcaaggcaa cactagctga agctttaaaa taatccttca gctcagcctc
    52741 taaagctacc gcatttttca aatctagagt ttcagattct tcgatcaaag gagagataac
    52801 ataggcctgt gtccccttag caagctcggt ctttacccag gccagcacac tatctaattg
    52861 ccgatgcttg acccagcgag tgatgattgg ctttcgccct gccggtaatt catcaataat
    52921 ggaaacgtcc atctcaccat aggcagttat ggctagggtt ctaggtatgg gagtagctgt
    52981 catcatcaaa acatctggat tgttgccttt ttcgcgaaac aagcgacgct gattgacccc
    53041 aaaacggtgc tgttcatcag taatcaccag ccctagctta tgataggtca ctgcgtcttg
    53101 gatcaaggca tgcgtcccaa caatcatatc cacagaccca tcagcaatag ccgataaagc
    53161 tgctcttttt tcagctgctt tcatacccga tgtcaacagg gcaatagaca aatctggaaa
    53221 gagctgacaa agactatcgt aatgctgctc agctaaaatc tcagttggca ccatgagtgc
    53281 cgattgaaat cccgctgttt gggcagcata catggcaagg cttgcgatca ctgtcttgcc
    53341 agagccgaca tccccctgca acagacggtt catatgagcc cctgaggtca tatctgctaa
    53401 gatttcctcc aggcttcttt gttgagctct ggtcagtgaa aagggcaaag cagcaatctt
    53461 ttttgccact gcctgctgat gaaaaggaat cgctaaccca ttgccctctg ccttgttagc
    53521 aagctttaaa acctgcagat tcatctgaaa atagaaaaat tcttcaaatt ttatacggcg
    53581 cagggcctgc ttataatcct ccatatgttt aggaaaatgc atggcataaa cagcagcttg
    53641 tctcggcagc aggcggtatt tctgaatcaa gggctctggt aaattttctt ccagctgagc
    53701 taaggcaccg ctatcaaagg ctgatctgat cgccttaatc agggtgggtt gactgatccc
    53761 ctgcgccaca tgataaactg gctgcaaatc atcttctaag gtcatgagca atttcatacc
    53821 tgtcaaggct gctttttttt gatcccacct accaaagata gccacttcct gatccaagac
    53881 gattttctca agcagataag gctgattgaa aaagctgaca ctaatcacaa gctccccctg
    53941 cttcaattta aagctcaggc gattacgctt gaacccatag tattgaacgc ttggtggagt
    54001 cacaactcta cctgtaagga cagccttttc accatctaaa agctctaagg ctgacttgct
    54061 tttaaaatcc tcatagcgaa aaggataata gagtagcaag tccttgatct gataaatgcc
    54121 taatttttga aatttctcag ctgactttgg accaagaccc ttcaaattag caatcgaact
    54181 ctttaacagc atctcaacct cgctttcttt ttcattatta tatcaaaaat caagagcctc
    54241 tccaaaaagg aagaggctcg ttttcttact gtagatgcct tgaggtatta gccgatccta
    54301 acacaccctt agtgcggccg ctaggacggc ctaactaaaa gatgaagagt ggcatataaa
    54361 caatacagca ctgcttgcta ggccaagata tgccctagaa ttgtgatagc tactgctagc
    54421 ttgtcaagag ttggcggctt gtgattggtc aatcgcagct agtggttatc agatcaagca
    54481 ggaacacctg ctgctccaag gagcgataaa gccatcacca atacagcacc agaccgcttg
    54541 agcaaggcta ggcctttacc tgctcaactg atagatacta tcacaggctt gatccagtaa
    54601 ttcctcgtca tgagagatga caatcactac ctttttttgc tgctttagct cctttaaaag
    54661 actaaccaga gcctgcattt gcagcagatc taagccactg cttggctcat caagaatgac
    54721 aatctccttg tcagacaaga ggctggcagc aatcatcacc ctttgctgct caccacctga
    54781 taggctggca gggtgcttgt ctagaagctg agaaagccca agcctattca ccaaatcatc
    54841 agtagcctga tgtctatgat gacctagatt aagctccttt tctaccgtct ccgaaaatag
    54901 ctgtagccca acgtcctgca acactaggct tgtgattgaa agcctgtcct tagcaggcag
    54961 ggtgacaccc agatagctga tcttggcctc ttttgcttca aaaatacctg ccagatataa
    55021 agccaactgc gattttccca aaccgttagc tccggtaatg ccagtgattt gccctgcacc
    55081 aaagctgagc tgattgaggt gatacaaaac cctgctgcct gccttgacct ctagctgctt
    55141 gatttgcaag gcatgctctg gatcataatg ctcaaaaaca gtttttgccc gcaaagcctt
    55201 agtcacagca gtcaactcac atcgtcttag tcctagctcc tcacgttcct gatctggcaa
    55261 agctagcaga tccttggggc ttaatacgcg ctctagccta ccagctgaaa aatagtaaaa
    55321 atggtctgcc aaatccagca aataatgcaa gcggtgctca gcgacaataa tggttttgcc
    55381 agcagcctta agctgcttta aataagcctt gaccgctgct acactagcat ggtccaaatt
    55441 ggctgttggc tcatcaaaaa ccatgatagc tgtcccttgc atgatagctg ctgcaatagc
    55501 cacccgctgc ttttgaccac cagatagctt aagcatatct gcttctagta agtccttgat
    55561 gtcaaaatca gctgccaagg tatccagcct ctcaaggata agagctggct ctaagccttg
    55621 attttcacaa ggaaaaacaa gctcatgctt gacctcacga tagaaaaatt ggctggctgg
    55681 gttttgaaag acagaggaaa cctgccttga cagcacttca acactagcct gaccagcctg
    55741 atgagacagt actttcagac ttccttgtaa ttgtcctgaa aaatagtctg gaatcaagcc
    55801 attgagcagc ttaagaaagg ttgacttgcc tgagcctgac tgaccacaaa gcacgataaa
    55861 ttgacctgcc tctatctgac aatccctgag ctcacaggca gtctgcctac gattggtata
    55921 ggaaaactgc agctgctttg ccttgatcac tggagaacca tgtaggctat cgtcacaaat
    55981 atccaaatct gtacccccca atccttccat gatagatgtg atacgaagca ctcacttgct
    56041 ccctttttga ttgctagccc ttttgttagg ctagcaatgg ttaagtcctg actacttctc
    56101 agcaatgaca tcaacagcgg taccaagaga tactccatat accgccttgg ctgtctgaca
    56161 atagcccagc tgtccaagaa aatgcccctg attttcagag attgccgaat aatctttcct
    56221 tcttgcctga tcttaggtaa aaaacgcagc atgacagcaa gagtcaacag acaaacctct
    56281 ggcacatgcc attttcgcag cccatgcaca agctcgtagg cagtcgttgt cttgacaaaa
    56341 atcaaagcag caagcacaga tgggtaaagc aattgaccag caacagctgc aaagctcagc
    56401 agcctaaaca gataggctgg cagcacatga agcggcaata cagacaaagc aagcagtaag
    56461 gcatagagca gtgtcatacc gattgccaga cgcccttgac caagccaaaa caaaatgcca
    56521 agcaaaacac ctataatcat cgtccccagc cagccatcaa tccgaaaaaa gaagcaggca
    56581 ttggctagaa ttaacaggag caattttgtg cgaacatcaa gcctcataaa agcattcctg
    56641 acttagcaaa atgctttttc agcaggtatt gaccaaaaag gccacctact aaggcacaaa
    56701 gaaggacaac accaacaaac cagctaacat ttgcaacggt aaagtcatac atgatacggt
    56761 taacatatgc catgtcctta ccacgcgcta aaagactctg gatataggcg tccttcaaca
    56821 gccacattaa aataatagga ccactgttaa caaaggcaaa aacaagataa gacaagagat
    56881 tcactagtct agattgatat tttcctaaaa gggctatgcc atctgccaaa cagccaaaaa
    56941 gaatagctgg tagcattgaa gcaaaaaaat gacctgtcaa aaagaaaaag cttcccataa
    57001 taattcctac taggcttatc ggtccaaagg tctgcagctt agcgattaat agcatataaa
    57061 ctggcccgcc aagcaaggcc gcaaaggctg gcgcatagag catattgcct gagcgatcaa
    57121 acagaatgct cagcatggct cctagcccca cacaaacgaa atagagggcg gcaaaggcgc
    57181 ctgttgtcat gatatcttta atggttaacc ctttcattgt ttacctcctt caaaaaacca
    57241 tttctcacac aaaatagctg gtctgcacag gccaaggtgg atggccgatg tgaaatcaaa
    57301 aagaccattc cccggcaatg ctttttaatc aaatcaataa agatggcttc attcagcgaa
    57361 tctaagtttg atgttggctc atcaaaaata tagcaatccg cccgcttcaa tagagcccgc
    57421 atcaattcca agcgctgggc ttcaccagct gaaaagtctg ctgatcctct cactagggta
    57481 tctagcccct catcacaggc taggatacgc tccttcatgc cacaggcctc agcaagttcc
    57541 atgatatcat catctgaaat gtccttacga ccaagtgtga tattgtcacg aagtgtttgc
    57601 tgaaatagct gcgcattctg tgggacatag gcaaagttag cctgtaggga agcagcattt
    57661 agcgtttgac tgtcaacctc actcaggaaa atatgaccag cttgccaatt gtaccatttc
    57721 ataatgatct tcatcagagt tgacttccca gagcctgact ctccctgaat accgataatg
    57781 cctttctttt caaaagcgac ggataagtgg tggtaaatag tctcctgatg cttgggataa
    57841 gcaaaggtca gatcctcaac agcaatcctt gttaccgagg aaatacgctg atctccctta
    57901 tctactaacg cttcttcatc taaaagctga aagacattcc tagcagcatt catggcacgc
    57961 ttgaagccaa gcggcaaacg ccccaattct aaaaagggtg caaaggaggc tgtaaaggca
    58021 acaaaagcca gcaacccacc agcaaacgtc accgtctgct gactcagctc aaaaagagta
    58081 acataagcaa aggtcaaaat agacaagcca agagccaaaa aggttatcgc catttgtaaa
    58141 aattgagcct gtgccacctg acgatcaagc gcattaacat gcttgctctg attggataag
    58201 agcttaaagc gcttctcaat gctttgaaat tgcagcaaat ccttaacaga tctgagactc
    58261 tctaaaaagc ttgacacata agccctgcgc ccttcatttt gctttttgag cagtgattga
    58321 aggacgtttg aaaaatacac tggaataata acagccaaaa gcacataggt cacaatagcc
    58381 cccaaggcta acttccagct aacctgccaa aggtaatagg ccatcaagct agctgaaata
    58441 aacgccgtac aaataggggc aagcgtgtgg gcaaaaaaga cctccaaggc ctcaatatcc
    58501 tcgccaatca tctttaacag gtgcccgctg tcctgactgt ctaagcgtgc cggcgagagt
    58561 gctcttagct ttttaaagac aatcctgcga aaggctgcca ggctatgaaa ggcaacaaaa
    58621 tgcccaaaat aatgctctcc ataacgaaca agccccctta gcagtgccat agcaacaaat
    58681 agataaagcc atttaaaggt aatagcatga ccagccatca cctctaagcc cagataggct
    58741 aagctggtag gaatgccaac ggtaagcaca aagcccagca ctgcaaacat caccgccaga
    58801 gctatccaag ccagcaaatg cttcatcata gcaagcaatc gtaaaactag ccggtaggtg
    58861 ctgtaatcac tcttaaccat aaagatttgc ctccaattct acttgtgtat caactaattg
    58921 acgataggcc aaatgatggc ggtaaagctc tcttgggcta gccaagctag cagactgctc
    58981 agggcttaaa aagagcacct gatcagcctg cttcaaatat ttcatcttat gagtgatgac
    59041 aattacaatg gcctgtttag ccaattgctg aagcagtctg tgaatagcag cttcattctc
    59101 agcatcaaga cttgaggtag cctcatcaaa aatataacag gaacgctggc tcaataaggc
    59161 cctagcacaa atcacctgct gtctttgccc tgcagataag tgacagccat tctcacctac
    59221 aatggtatca atcccatcag gtagccagta aataaagctc aaaatgccat gctcatcaat
    59281 ccagctaagc agctcctttc tagtcagctg agctgccata gcaaggttct cataaatact
    59341 catattaagc agcgttgact ggtcagaaac gtagagtatt tcctgattga tggcctgttt
    59401 agaagccaga tcaatcgtca catcaccaag gaatatctga ccgctatctg cctgatagcg
    59461 cttcaacagg agctgtgcaa gactagtctt accctgtcct gaaacacctg caacagctgt
    59521 tagctcaccc tttttgatag tcatcgtgat gtctcttagc aaagcctttt ccccatgtga
    59581 aaaggacaaa tcttgaatat caatacgatc aaaggccggt aaggcaactc ccttgtcttg
    59641 gtcaacagcc tcaacactat ctaaaaagcc aaagatttga tctgccattt tagtattcat
    59701 catgactagg tgcatgccat agccctgctc cctaataggg gcaaaaaatt ccgttgcaat
    59761 caggataaaa aagagaaagt caaaaaagga tataccacca gctgacagag cctgaaccgc
    59821 taaaaagcca gataagccaa tgccaagata catgacagcg tccatatagc caaccgcttg
    59881 cagctgaaag cccaagagct gcatggtagc cttacgaaag gcctctgcct tattgacaaa
    59941 gctttcctca tacctttcat ctgcctgata ggaataaagg gtatttagcc ccttgagatc
    60001 gtccataaat agattgccaa cgtccatata ggttgaccag taatggttca tgatcctttt
    60061 agagcgtttt tgcatagcaa caatggatat gggaatcaag ggcaaagaca agataaagac
    60121 caagccccct ataggataga tcaaaaaaac aagcagtaag accgttgtgc aattaaaagc
    60181 tgttagcatt gcaagcgata ggtaatagga ataataggta tccaagctat caatcccttg
    60241 tgaggcaacc gttaacacat cagcctctgt tgactgctga tcaaattgcc cgtccatagc
    60301 aataaaggca tcaaaaaagg attgcttgag cgagtcacgc gcaaattgcg aagctaggcc
    60361 ctgcagctgc tttgcaatca tcgccaagcc aaagccaaca gcatttaaaa tcaaaaggat
    60421 aacaagcagc cttgtcaatt gcagggcttg acctgctaaa aaggctgtga attgcttagc
    60481 aattaagtaa aagctcatta aacgcatcaa aaattgcagc caagataaaa aggccgacac
    60541 ataaagcaaa aaacgcttag gagcaatacg ctcctttaaa cgccttaaaa gcattttttt
    60601 ctttgcgcgt gatatttttt cagttgtatc gttcatataa tcgtcgcctt attcctatct
    60661 atcattcatt ttttatttgt ctcataaagt ggtaagaaca aatcgcctat cctgcttttc
    60721 aataaagggc aagctcaccc caaaaaccgc ctccacaaaa gcctgatcaa gaacctcctg
    60781 tggactgcct tgggcataga tggcaccttt ttgcagccca agcacacaat ccgaaacagc
    60841 caaggcctga ttaatatcat gtaacaccat gataatggtc attcctagct cctgattgat
    60901 ttttttgatg agggctaaaa tgtccagctg gtacttaata tcaagataag tggttggctc
    60961 atcaagcact aagacacctg ttttttgggc aagcgccata gcaatccaga ccctttgctt
    61021 ttcaccacca gatagctcct gcatttccct aaaggccaat tcccttagat tagtcacctc
    61081 taaggcccaa gcaacaatgt catcgtcctc ttgacttgat cccttaaaaa aacgccgatg
    61141 ggcttggctt gccacagcca ccaaatcacc caccagaaga tctgctaccg cctgattatc
    61201 ctgatgcaca acggctactt tttgggcaaa ctgcttaaga ctaatagagc taatagcttg
    61261 tccctctaag aaaatttgcc cagacttaac ggggatattt ttagtcagca gacctagtag
    61321 ggttgatttg ccacagccgt ttgcccccat gattgtcgtt atcttgcctt ttggaatggt
    61381 aaagctcagc ctatctaaaa taggcctatc acgataagta aaggacaaat cctctacacg
    61441 aatcaagcct tgctcatgac tcatatcacg tcagacctcc ttaacagata aataaaataa
    61501 ggtcccccga caatgctcat gataacagct gggctaatct ccaagggata acacaactgc
    61561 cttcctaagg tatctgccag caaaaagaca aaggcgccaa gcagggcaga aaaaggaatg
    61621 agatagctat gcttactgcc aactaaaagg cggccaatat gcggcacaat caggcctaaa
    61681 aatgacacca cacccacaat cgaggtggaa acagcagcta gtaagaccgc aaccaacgag
    61741 attcctaagc gcaggtaatt actatcaatg cctaaattac gaatcaagcc atcgtttagc
    61801 agcagtagat cacactgcct tgctaggcct atcgcaagca gcaggccaag cactgtataa
    61861 ggccacagca caccaacatc tgcccaggtt ttttgactaa tatttcctga caacagcgca
    61921 ttgacaaagg gattgctggt ttttgaaaaa tcagtaatcg cacgagacaa gcctaaaaac
    61981 aaggcgttga tagctattcc tgtcaaaatg atgcgtatcg gctgcaagcc cttcttccag
    62041 gacaaggtat aaatcatcaa aaaagaaaca cagcctccca caaatgataa caaaggacca
    62101 taaaacaaga gctgcggcaa aagcaggcta gataacaaga ccataaagct agccccactg
    62161 caaaccccaa taatcgccgg atctgaaata ggatttttta aaatcgcctg aaacaagacc
    62221 ccagatgttg ctatccccgc cccagccaat aaagcaatca caatccttgg aaagcgtaaa
    62281 tcgtaaataa gggctacctc tgaatcatat gctacaaata agccattaaa gatcctctga
    62341 taagaaacag ataagccccc aacagagacc gcatatagca ttaaaccaaa cagcagcatg
    62401 agcaatagaa ccatatagac cagtctagtg gtcctttttc ttgctgctgt gacttgatca
    62461 gaatattgac taccttgctg catcttactt gacttccttt gctccataaa agatttgtga
    62521 cagatggttc aaagcctctt tgtagttaaa cttagcactc atgccaaaaa gggtattgtc
    62581 taaatcataa acctgctgag acttgacagc ttcaaaatgc ttccaaatat cattttcagc
    62641 aaattcctta tcaaacatgt ccttaacctt gtctggaatg gcgtgggcag tacgcaaaat
    62701 cagctcaggc tgctgctgaa gcatgtcttc tggattggca gacaaaaatt ccttgtcctc
    62761 agagtgataa acattctcac caccagccag ctcaagcaga ttaccaacat aggatttatt
    62821 tgtagcaatc agatagctgc caggaagccc catcaaaata agaaccctag gctttttttg
    62881 ccctttatgc tttttcttaa aggcccggta aaactcctca taatcagccc gcaagcgctt
    62941 agcttccttt ttgcgatcaa acaagtcccc caaatcatca atcgactggt acatgccttc
    63001 aaggctagtt aaattcaaaa agccatattc cgtatccaat tgctggtatt taggctctaa
    63061 atcattttgc agagaattgg gactgagtat ccacgttggc tttagagaag caataacctc
    63121 catatcagga ttcatcggca gaccgatcct tttgacagca tcgtaacgct ttggcaattg
    63181 gtatagctta ctgtcacaga ccccaaccaa atctaggctt agccgatcac aaatatcaac
    63241 aacagccaca gaggtggcaa caattctctc cttatcagcc tttttctctg ccctagggtg
    63301 ctgatccaca caagcagata gcaccaagga caaaacagct aatccaataa gcttaatgac
    63361 tttcttcatt gttttttctc tttttcttta taaacaagac caaggctcct gacaacaaaa
    63421 gagctgttgg tacatagtaa accagaactg gcaatggatt atttactggc ttttgggacg
    63481 actcttgctt acttttatct agcgaagtgc tcaaaccaac tgcctgaccc ttcttagagg
    63541 gatttgactg ttttttggga ctgcttgatt gaccaactgg ccttgctgag ggattaggag
    63601 ctgacttggc gtcttttgag tccggtttac taggagcttt cttctcatct gcctttgcag
    63661 gagctgtcac cgcatgatcc gtcttggctt ctcctgctgc aaagctagct accatatctc
    63721 cactgtagcc ttcttgtagc tcagatggtg acaggtaaaa gacaacctct ctgcccatag
    63781 gctctacgta catgctgcct ctaacaaccg tattgacatc aggcaaagca atcgcaatat
    63841 cctttgttgt gccattggta tcagtgccaa ccttggtgac actgtaggct gccgcctgaa
    63901 aagcccctgt accacccggc tgaacccaaa attggtagtt acctgaaaaa tcagctagac
    63961 tcatgcgaaa ggtcagatac aaatccccag ccgaggttac ctctagcata ccattgctat
    64021 aaactgttcc ttccaccata ccttggccaa tctcaaaagc gtgctcacca ccgctatctt
    64081 caatttgccc tgaaaccggg tgacgataat ctcgcctaat cacacaggaa taaagctcac
    64141 ccttatcagc ataggcctta cctcctatag ctgctaggca aaccagcaat accaccaagc
    64201 cacccattaa ttttttgaat aatctcttta tcatatgttc ctcattaatg atcttcattt
    64261 ccttacgaca atcaaataag gcatagattt agacgcaggc caagacctac tcttatttga
    64321 ctattataac acctcaaata cgaaaagcat acccattcct cacttaccaa gggtaagctt
    64381 aagaaatcat tagaaacagg catgccttta cgtatcgttg ataagccttg atgactacaa
    64441 gcgattaaac caagctctta gtgcatcaaa cagactctct actgacttaa aataattttt
    64501 tcctaccaag aatgagacca actgctatga caataaagct tgctagaccg ataatgatat
    64561 ggccgcgatg atcagctttc atctgctcct gactatgttt agcagcctta gatttagctt
    64621 tggctctagt cttagcagcc tgcttagagg ccttgcctgt accagcctta gacgccttat
    64681 gtgaagaaat caggctctta agcttatctg taccggtctt agcgtcctcc ttggcattac
    64741 tgcttggagc agctgacttc ttagtcaaaa gattggtcaa attaggaata gcaggacttg
    64801 tatgaccacc aatgatacct gtgtgaggct gcaagagctc acctatggta ccatgtccct
    64861 gattgtcctc tgagtgtggc aattgtgcct tatcctttgt caggctttga agatccaact
    64921 tcataaagac tgtctggaag cctgttccct tagagatagc gtccataatt ggcacaaaga
    64981 cgcgaagagg taccaagcca tcctttttag cctgatcaat cagcctaaat ctcaacacct
    65041 gtgggtaatt gctgccataa gcgtctgaca ggggcttgcc tgtgacatct gtaaagtagg
    65101 acacaacctc tgctttttct gtcttaccaa ccggtctgcc agtcaaatcc ctttggtagc
    65161 catcaacaaa gtagctcaac tctccgagat accctgtcag gttaccgatc ttcatgccct
    65221 taaaggtcac ctctaggcta tagacaccct tattcacaat caatttgacg cggtggtcaa
    65281 tagcctgatg agacattgat tctgactgca aatcattttt aagcatgctt gccttgatgt
    65341 agtagacacc atcttcaagc ttattaatat ccaagccctt agactggtca ctacctgcaa
    65401 gctgatcctc cttgacctca acatcattag aggtcagata aatatgctca cgcttcttag
    65461 caaattcctt ggtgataaga gccttacgaa cacgataaac acctgctccc tttaggtcaa
    65521 aggagccttg aagctcatct tgtggatcgt tattcaagcg tctctcatca acggtgacat
    65581 attgaccggt tgatgttttt ttctgcaatt gcaccacaat atcccagtca gcataacgct
    65641 catttaataa ggcaatgatg tctgacgagc ttgccttaag gcgtttattg taatcctcaa
    65701 cagagctaat ttctgcttcg gtgcttgaga gtgtctgctg ctcccaataa tacaaatcaa
    65761 gcaggctaaa cccttggtga taggtcatcg cttgatgatt taaagtcgca gatagattag
    65821 caaattgctt ttgtgggttt agcttatttg ttcccatgat ctgtctaagc ttatcactaa
    65881 cgccacttag gcagttaaac ttaagatcaa gatccaatgc ctttagatct gcaaaatcag
    65941 cttcgctaat attcgttaaa aggttattat agacattaag ctttgatagc tgcttattag
    66001 ccttgaaggc tccctgtggg attttagtta gctcatttga tgccaagtca acggttaata
    66061 agtttggcat atgactaaag tcaatattag caatatctaa aacctggttt cgattggcaa
    66121 cgatataaga aagcttagtt agcttactca aggagcttgg caggctgccc aactggtttt
    66181 cagaaacatc aaagaagttt agattatcaa gtgaagctag agcattttct gaaaattcag
    66241 taatgatatt ttcagccaag gccaaggagg tcaagcgaga tagaccatta aagacaccat
    66301 ctcgaatcac gctgattcta ttttttgaca gatctagctg atccagctga ccaagatttc
    66361 taaatagtcc ttcctccaga tttggcatat agttgcttga gagatagagc tcttttagct
    66421 ggctgttatg agcaaaggta tccttatcta gggttgtaat cacattgctg cgaagattta
    66481 agaaccttag attggtcatt tgactgaagg tttcctttgg aatgcttgca atctgattgc
    66541 cctctaagtg cagctcagta atatgcttag catgctttaa gagtgaaata tctgtcaaat
    66601 catagtggtc taggcgcagc tcaccttcaa tcttcgcaat ttcctcaggt gacattttgc
    66661 catcaccgtt aaggtcctta ccaagcttaa ccaaaacctt ttcaagacgc tcagagccga
    66721 cccctttttc cttgtcgtca atctcagcct gatagcctgt ccagccctta cttgctgtag
    66781 cgctaaaggt catgtccaac ttggtgtatt tgtcatagtg atgtaggtcg ctttcctgac
    66841 cacccatagc tgatactagc acagcaccct tgtgaagctt gtccagctcc tcaatcggta
    66901 gggtaaattc actctaatgt agttattgtt aatatcgcgt tcaccaacct gagtgcggac
    66961 agaggttgga tactgccctt tactctcaat ggaaaagtca atcaaaaatt gccctagagc
    67021 tgtattgagc aatgaaatct ccatcttgcc atcttctttg acgaccagct tggccttctt
    67081 atcaaatgct ccctgcagca ttgaggcttc ctctgtattt tccttattgg ccttaaaggt
    67141 taaggtatag gttcctgcct ttagatccgt aacagccaga tcagttccct gataggactt
    67201 gatactatcc atcaaaagct cataggtctc cttgagcaat ttttcattgt caatctgacg
    67261 ataggactcc ttgatcacct gaagcttgct agacaagtcc ttgacctgtt ctttattggc
    67321 ctcgctagca atgatacgct cagcttcctt gatcgcgctt tccagcttag taaaatcaag
    67381 tccctgcggt gcttcctgct gggatccttg tctctgcttt tgcttagcag aaacaaaggt
    67441 gtattgctcc cctgactttt tcactgtaat gatgacatct tcaaagcttt gtgaggaaat
    67501 gacaaccttg ttttctccct ccttgaaagc tgtcgtccca agatgaagcc ccttcaggtc
    67561 agacacatag ccaggcttgt cctttactga atcatagacc aaatccttat agtcctggtc
    67621 attgaccttg atctttgtga tttgatgagc taattcctta atttgcttgg tgctggaata
    67681 gcgatcaatt tccggaaaaa gaagctctcc ttctgttgtc tctagtttgg tgataaatga
    67741 tagggtcgct aagccatcat ggctagttac cttagcaggc ttttctgtct tagcagcagc
    67801 ttgctgcggt gaagcagtag tatcatctga aggcttggca gaaacaaagg taacatcatt
    67861 tcctttcttg tcaaagacca caagaatgcc tccgttagtc ttattgacga tgcgcagctg
    67921 atgctgtcct tctgtgatgt tcttagcgtt taccttgatt ccttggtaat tgatgtcata
    67981 gctatagtca ccctccagct ttttgtcata ctctttacca tcaatgagaa ttttctcgat
    68041 atttttataa tagagcttcc cctctgactt gtccgcatag ggaccgatct cctcgaacaa
    68101 taaaatatta tccttaagct tgacagtcgt cacaagactt gaagagactt gagtagcctc
    68161 tgagcgaacc gtctgggcag actgggcaag agccagcgtt gataaagcaa gaatggcgca
    68221 cttattgata cttttcatta tttcgaacct tctaaaaatg ttattagcca tttaattatt
    68281 ttattaatct cacttaattt attatgttgt caagcctttg tcaagattga atttgagatt
    68341 tttttcacaa taaagcaaag aaaaaaacag ccctgcaaca gagctggatt ttttcttaca
    68401 aaaattctgt acttctcgcc tttaaagcaa gaagattact tatgattttc caacaacata
    68461 agtcaattgg ttggcctgct cagcagtaaa ggtgcggtat gaaatctgac ctaagccaag
    68521 acaatttgac tctgaaatca ggatggagcc gtcctttctg acatcctcaa caatagagac
    68581 gtgcccataa agaccgtcag cacccgcttg acctggagca aaggaaaccg catagcctac
    68641 ctttggctcc ttagaaatac tgtagccaga cttaaatctc cagtcaccac catttcccat
    68701 aaaggaatca aactgatagc ctagctcctt agcgcgatta taaacatacc aggtacattg
    68761 tccccaagca tagcttgacg cctgatagct taaaatatca tagctcttag acagcttgta
    68821 gcctgtagga acaacagcaa agcttgaaga ggattgaatt ttcagctcag ccggaatctc
    68881 tggcgtgcct ccatgctgat caatccaagc atctaatttt tccatgatct cagcgcgacg
    68941 cttgccaatg ccattggtat ctgtgaagta aagaccacca tcactagcaa agttcaactg
    69001 ctttttggca aatttatcag ccttttgatc ctgctgctca aaattaaggt tgctattttt
    69061 gataatcgtc tcctgtgtca gcttaacaat agcaagctca tcattaaact gatttggctt
    69121 tttcgaatca aggtcaaaaa gcgcatagcc aaacatgtta gagcctagta aggttgcatt
    69181 tcccttggtt cctagctcac tttctgtcat tgcaatggct acaatcgccc gcacatctag
    69241 cccactcttt ttttcccatt gcagcaaggc agcaccgtta attcgcttct catcatactt
    69301 gatcttggta gactttaaaa agctatcaag ctgctctgcc ttgatcccat agcgcctaga
    69361 caagaggtta tgggtataag cactctgacc actccaatgc gtcacataag cagcataggt
    69421 atttacagaa ggcagggcca gagtcaagga caaatcaact gtaggagcag caggaacaat
    69481 attcagtgcc ggctgagatg cctgtgtagc aacttcaggg gctggctgag ggctagctgc
    69541 tggactagta ggtgtcgact gtccagtaga accagaagct gatccagagc tagctgtatt
    69601 gcttgatgac cccgttgctc caggttctcc actgttggga gtagtctcag tggttgatga
    69661 ggagttgtca gtagctgagg tagcagctgc tgtcgaagtg gactcaccag tctgggcgat
    69721 tgcagcctca ttagcagtag ctggaacctg gctggcttca gctcctgtat cctctgccaa
    69781 tactcttgcg gtctctaaat gaggtaccag aagagtcatc agcattatca ttcttaataa
    69841 tttatttttt ctcatttagt attcaatcac ttctttctgc tctattctaa cctacattat
    69901 aacattgaag caaaataaaa tgcaagattt tttgtattaa tgccttaata ctcggataaa
    69961 ggtaagggcc ttttctt
//
LOCUS       DARYLJ010000003        65903 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYLJ010000003 DARYLJ010000000
VERSION     DARYLJ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65903
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TU746_000146"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TU746_000146"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL0890542.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TU746_000147"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TU746_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL0890543.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TU746_000148"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TU746_000148"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL0890544.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TU746_000149"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TU746_000149"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL0890545.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TU746_000150"
     CDS             complement(6925..7623)
                     /locus_tag="TU746_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL0890546.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..9030)
                     /locus_tag="TU746_000151"
                     /pseudo
     CDS             complement(8009..9030)
                     /locus_tag="TU746_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(9565..11244)
                     /locus_tag="TU746_000152"
     CDS             complement(9565..11244)
                     /locus_tag="TU746_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890547.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(11419..16323)
                     /locus_tag="TU746_000153"
     CDS             complement(11419..16323)
                     /locus_tag="TU746_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL0890548.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            16676..17503
                     /locus_tag="TU746_000154"
     CDS             16676..17503
                     /locus_tag="TU746_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL0890549.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(17579..17932)
                     /locus_tag="TU746_000155"
     CDS             complement(17579..17932)
                     /locus_tag="TU746_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL0890550.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(17936..18448)
                     /locus_tag="TU746_000156"
     CDS             complement(17936..18448)
                     /locus_tag="TU746_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL0890551.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(18905..19459)
                     /locus_tag="TU746_000157"
     CDS             complement(18905..19459)
                     /locus_tag="TU746_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0890552.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            19670..20299
                     /locus_tag="TU746_000158"
     CDS             19670..20299
                     /locus_tag="TU746_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL0890553.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            20758..21843
                     /locus_tag="TU746_000159"
     CDS             20758..21843
                     /locus_tag="TU746_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890554.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            22029..23267
                     /locus_tag="TU746_000160"
     CDS             22029..23267
                     /locus_tag="TU746_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0890555.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNRTLDIYISKDRNSKFQNLLGSTLVVKTPENKENCQCTKIYI
                     EENGKDGYYLYIYEDTNKNDKYDKNKDKLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQ
                     GPQGPRGDKGETGEKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPG
                     EKGDPGQQGIPGPKGDPGKDGEKGERGEQGPQGERGEQGPRGENPTPTPDPMPQPMPD
                     PAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVL
                     GTGLLSLLGLGFLTRRKRKQ"
     gene            23580..24875
                     /locus_tag="TU746_000161"
     CDS             23580..24875
                     /locus_tag="TU746_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0890556.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPDPQPKPEPKPQPEPKPEPKPQPVPKPDPEPMPDPEPKP
                     QPEPKPEPQPEPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQ
                     SSGKGLPRTNEAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(25008..26126)
                     /locus_tag="TU746_000162"
     CDS             complement(25008..26126)
                     /locus_tag="TU746_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890557.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(26123..27250)
                     /locus_tag="TU746_000163"
     CDS             complement(26123..27250)
                     /locus_tag="TU746_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890558.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(27259..28182)
                     /locus_tag="TU746_000164"
     CDS             complement(27259..28182)
                     /locus_tag="TU746_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890559.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(28205..28891)
                     /locus_tag="TU746_000165"
     CDS             complement(28205..28891)
                     /locus_tag="TU746_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL0890560.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(28888..29559)
                     /locus_tag="TU746_000166"
     CDS             complement(28888..29559)
                     /locus_tag="TU746_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL0890561.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(29534..30892)
                     /locus_tag="TU746_000167"
     CDS             complement(29534..30892)
                     /locus_tag="TU746_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL0890562.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(30905..31969)
                     /locus_tag="TU746_000168"
     CDS             complement(30905..31969)
                     /locus_tag="TU746_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL0890563.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(31966..32916)
                     /locus_tag="TU746_000169"
     CDS             complement(31966..32916)
                     /locus_tag="TU746_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL0890564.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(33144..33308)
                     /locus_tag="TU746_000170"
     CDS             complement(33144..33308)
                     /locus_tag="TU746_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL0890565.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
     gene            complement(33837..34094)
                     /locus_tag="TU746_000171"
     CDS             complement(33837..34094)
                     /locus_tag="TU746_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL0890566.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(34631..36670)
                     /locus_tag="TU746_000172"
     CDS             complement(34631..36670)
                     /locus_tag="TU746_000172"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL0890567.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(37036..37947)
                     /gene="glyQ"
                     /locus_tag="TU746_000173"
     CDS             complement(37036..37947)
                     /gene="glyQ"
                     /locus_tag="TU746_000173"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL0890568.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(38313..38846)
                     /locus_tag="TU746_000174"
     CDS             complement(38313..38846)
                     /locus_tag="TU746_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL0890569.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(39113..39337)
                     /locus_tag="TU746_000175"
                     /pseudo
     CDS             complement(39113..39337)
                     /locus_tag="TU746_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(39367..40206)
                     /locus_tag="TU746_000176"
     CDS             complement(39367..40206)
                     /locus_tag="TU746_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL0890570.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(40293..41441)
                     /gene="nagA"
                     /locus_tag="TU746_000177"
     CDS             complement(40293..41441)
                     /gene="nagA"
                     /locus_tag="TU746_000177"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL0890571.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(41558..43199)
                     /locus_tag="TU746_000178"
                     /pseudo
     CDS             complement(41558..43199)
                     /locus_tag="TU746_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            43390..44136
                     /locus_tag="TU746_000179"
     CDS             43390..44136
                     /locus_tag="TU746_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890572.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(44742..45584)
                     /locus_tag="TU746_000180"
     CDS             complement(44742..45584)
                     /locus_tag="TU746_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0890573.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            45716..46273
                     /locus_tag="TU746_000181"
     CDS             45716..46273
                     /locus_tag="TU746_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0890574.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(46684..47508)
                     /locus_tag="TU746_000182"
     CDS             complement(46684..47508)
                     /locus_tag="TU746_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0890575.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(47513..48127)
                     /locus_tag="TU746_000183"
     CDS             complement(47513..48127)
                     /locus_tag="TU746_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL0890576.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(48288..49160)
                     /locus_tag="TU746_000184"
     CDS             complement(48288..49160)
                     /locus_tag="TU746_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL0890577.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(49371..49856)
                     /locus_tag="TU746_000185"
                     /pseudo
     CDS             complement(49371..49856)
                     /locus_tag="TU746_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(49859..50125)
                     /locus_tag="TU746_000186"
                     /pseudo
     CDS             complement(49859..50125)
                     /locus_tag="TU746_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(50127..51059)
                     /locus_tag="TU746_000187"
     CDS             complement(50127..51059)
                     /locus_tag="TU746_000187"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL0890578.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(51069..51584)
                     /gene="lacB"
                     /locus_tag="TU746_000188"
     CDS             complement(51069..51584)
                     /gene="lacB"
                     /locus_tag="TU746_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL0890579.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(51600..52025)
                     /gene="lacA"
                     /locus_tag="TU746_000189"
     CDS             complement(51600..52025)
                     /gene="lacA"
                     /locus_tag="TU746_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL0890580.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            52161..52943
                     /locus_tag="TU746_000190"
     CDS             52161..52943
                     /locus_tag="TU746_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0890581.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(53359..53910)
                     /locus_tag="TU746_000191"
     CDS             complement(53359..53910)
                     /locus_tag="TU746_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL0890582.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(53923..54873)
                     /locus_tag="TU746_000192"
     CDS             complement(53923..54873)
                     /locus_tag="TU746_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL0890583.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(55744..57975)
                     /locus_tag="TU746_000193"
     CDS             complement(55744..57975)
                     /locus_tag="TU746_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL0890584.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(57975..58409)
                     /locus_tag="TU746_000194"
     CDS             complement(57975..58409)
                     /locus_tag="TU746_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL0890585.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            58639..59676
                     /locus_tag="TU746_000195"
     CDS             58639..59676
                     /locus_tag="TU746_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0890586.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            complement(59748..60098)
                     /gene="rbfA"
                     /locus_tag="TU746_000196"
     CDS             complement(59748..60098)
                     /gene="rbfA"
                     /locus_tag="TU746_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL0890587.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(60288..63158)
                     /gene="infB"
                     /locus_tag="TU746_000197"
     CDS             complement(60288..63158)
                     /gene="infB"
                     /locus_tag="TU746_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL0890588.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            complement(63178..63480)
                     /locus_tag="TU746_000198"
     CDS             complement(63178..63480)
                     /locus_tag="TU746_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL0890589.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            complement(63473..63769)
                     /locus_tag="TU746_000199"
     CDS             complement(63473..63769)
                     /locus_tag="TU746_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL0890590.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            complement(63785..64939)
                     /gene="nusA"
                     /locus_tag="TU746_000200"
     CDS             complement(63785..64939)
                     /gene="nusA"
                     /locus_tag="TU746_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL0890591.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            complement(65049..65531)
                     /gene="rimP"
                     /locus_tag="TU746_000201"
     CDS             complement(65049..65531)
                     /gene="rimP"
                     /locus_tag="TU746_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL0890592.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
BASE COUNT        19220 a        15754 c        12740 g        18189 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatttctt tttttgccat ttttattccc ctttaaatat aatggacata
     9061 atgtctccta attatcaatg acagataatt acacttttat tataaaaggt attttctgtt
     9121 tagtcaagag aaaactgttt cttttacatt tctgttattt tacagttata tgtcacatct
     9181 gatttggttt aatttttctg aaaaaccagt agataaggca ttttaagcat tttttgatga
     9241 taagataata tcacaaaaca ttaattatat gacaattatt gtttttaatt attagaattt
     9301 ttaatcaaaa ctatcctgca atcagctgtt tagccatttt aaaaggcaaa caaaaaccat
     9361 gccacattgc aatgacatgg ttttcttcaa gaaaggagcg agctttggtt tggtactttc
     9421 tacaactgat ctccaatagc agctgctcct cgttagtccc tgagccacag gtgactgagc
     9481 tttcctgcgg ctactctgat agtaccagct actcttacaa ctgcataaag cagtggctgc
     9541 cagccaagct aaagctaaac aatattactc tgttatagct tggtctgctg acgagctctc
     9601 aatggtcatg tgattgaggt agttgtcatc agccagctga gccttaaact ggtctccgac
     9661 ctttaggaaa ggcagacggt cactagtttc actgcttgcc ttgattttat aaatctgacc
     9721 cttggaggaa atgtaataaa ccgttgttcc tgagataatc tggctggcca attgctccac
     9781 ctgcccagta atcatcttga ccttctgatc attggtgtct gacactgaca gcgagcttgt
     9841 gtccttatct gtgaattgtg agattaaggt ctgaatgtca ttattcactg ttacctgctg
     9901 ataatcctct gcatcaacca aggcatagga ttttatcaga ccagccccgt ccttcaatga
     9961 gataaggtaa taagccttgt catttaactt gactagggtt ggtgcagttg cagtgtattt
    10021 cttctcttga acttcgccct cggctgattt catggcagag gcctctgttg cagaaggcag
    10081 cttatagtta gtgacctctc tggtacgcat gttaaccaaa ataaagccga gatttgacga
    10141 atcagctgtt gctgaggtga ttcctgtata gaggtaaatg tctgagccga tggtaatgta
    10201 gttatagctg tctgttgttt gcttgacatc tgtctggcta aagacagtgt tccaatagcc
    10261 cttttgatag gtgtaatagt cattaaccct ctccaaaaca ttgtcagcag aatagacacg
    10321 atcaacccat tttggaacgt cctttagctc atagtattga gacttgccgc taaccgcgtc
    10381 taacaggatc acacccgtcg gctcctgaga ggacaggcca aattttgggg cgtaggttgt
    10441 tgcgacatag taagggttac catcgtcatc aacctcaaat gacgggtctg aaaaaatggt
    10501 catcgggtac tggaagcgca aatgcctcat ggtgtctcta aacataaatt ccgaatgaga
    10561 atacttcata ggctgattta acttgactag ctctgcctta ccagttgtct gattgacctt
    10621 gacataatag ccaatgccgt ccttacgatt ggttagccat ttccagaagg atttgtactc
    10681 caagggagaa acacgataag ggagcttgcc gatcgtaatc tgacggtact catcagaaat
    10741 accaaactgc gataccttat caatggtccc aagataagta tctccaatct tttcagccga
    10801 atctcgatcc agcaatgcca aggctgacag atcagtgtct ggaaaatcct tgttaaaatc
    10861 agcgtccttt accttaatca catgagcata ggacttagca cgaaacattc tagtattaac
    10921 agctaacagc aaggacaagc cagcaatgat aacagcaagg gcaagaccaa gccactttat
    10981 gccaccggtt aattgcttga gtgaaagacc tgaggtcacg tccttgcggc cagacttttg
    11041 cgtgaaaaag ctggtcactg tttttttcaa cccaaacaag gacaggataa aaagactcac
    11101 catcgccaag ataagcgcaa gaatcacgaa aaaccaaaat tctaagctca tcacgttcat
    11161 tggcggcaaa taaatccagt aaaagccagc caggatcaag ctgtctaagc caatcagcac
    11221 caaagaagca actttttttg tcatactaat ctcctcgtca caccctaagg ctatcagggg
    11281 tattcaatat cttctcaccg ctattgtacc acatttcccc tcaaaagatg acatctcagc
    11341 cagacatttt tatcagctct tagagcacct cagctagaat gatcaataca gctgacaggc
    11401 tacgctcata gagcttgctt agtacttctt ttgacgctgg caagagcctg ctgctccaag
    11461 actgagcaag cctagcagga ctagattgac cgctgcttgc tcacccgttg atggtaggac
    11521 ttgggctttt ttaactgctt gtgctgttag ggcagagcta gtgattgatg agccggtata
    11581 atgagtcaag cctccagcct gatgttctag ctgaggctgc ttagctttga taacctcaaa
    11641 ggtaagctca atcacgccat tatgtgatac ctctagacct ccttgaccga ttagctgata
    11701 gccctccggt agctcaacga ggacctcata gcttccttgt cgcagtgttt taccataggc
    11761 acttggaaca tagagagacg gagctagaga aatcaactga ccatttgctg ctttcaggct
    11821 gaccctgctg ccttctggca agacttggtt aaacaagagc caaacagaag ccacaatagg
    11881 ccttgtcatc tcaaaggcaa ctgaagcaag ccttgtatcc gcatctagac taaagctaac
    11941 caagttgtca gaccttagct caaacagatg attatcataa gccaagagct caacggtgta
    12001 gcgtccaaat ggcaatatca agctattagc tgagctattg aaatagtcca actgctcgat
    12061 tggcttgccc tgctcatcac gaataagata agtaaaggct ggctcttttt tgttctcaag
    12121 cacatcaagt gccaaggcaa cggacactac tcccttgtct ggtcctacag ctcgcaaagc
    12181 agctaagctc atataagcaa tctgacctgc ctcgtcttcc actagataat aataatctgc
    12241 ttctgcaacg ccttcaacct taggaatggt gtaggtgccg tctgcatttt gagcaatcat
    12301 caccttatta tccttgaatc tgatcagctg atcttcgaca gttagatcaa acttgcgtcc
    12361 atctttcttg acaaggtaga agacctcttc tctaacaata cctattggac tttgtccctt
    12421 gcttggtccc ggacgaaaga cctcagtagc accatcagct tggaagctag ctggcgtaat
    12481 gactggcttt tgatggctaa ctgtcaccgc ataggcctct gcttgaggca taccattagc
    12541 gtctagataa gaaacaacat agcgataatg tcctgacatc accctagctc ctgaggctct
    12601 tgtgccatac caagcggtgc tgtcaacatt agccacgctt gcacctggtt ggctagacca
    12661 gattgggctt gtcatagctg tatcctcctg ggcaaagacc gttaccttta gatcttgata
    12721 tacttgatgt ggcaagccct tgaatgccac aaaatccttg tttccatcat cattcggcga
    12781 gatgacagca gtttgaccta atttagccaa acgactctgt ggtctattgc ggctaataat
    12841 gagaagctct gcttcatttg tcaccagtcc tgtatctgca gcagtcatgt tgaggttatc
    12901 actgtagctc agctgatgct gagcattaat atcagttagg gtcaatgcca gctcagcctg
    12961 accgattttt tctggcaagt gatttcccag cttagcaatg gcaacattgc ctgcaaaatc
    13021 ctcgaccatg taataaaaat caccaagcgc cacctgatca actggcagga caaaagagcc
    13081 atctgctaag cgctcaacaa actgcttatt gtctgatacg gtcacatact ttaagccatc
    13141 attaatggta atcgtataag gcttgtcatc ctttgtttcc aagtaaaaaa cactatctcg
    13201 aagaacacca gcctgaccgc gatcaagcca ctgagacggt ctgaagcgat gggtcacagg
    13261 gttatagctt gctgttccta gctccggcgt ttgacgatcc acaatcacct caaagaccat
    13321 ttcttgacgt ttcgctccta ccacatctgg ataataagaa accacataat ggtatttgcc
    13381 atctggtagg tcagctccgg tcagcgattt accactaaag cctgtttcta acagcgttgt
    13441 tgacttggca aagcgaatat cactgttaaa gtttttatcc ccttgaaggg ctgatgggct
    13501 cgtccagagc aactccttac ggtctgtatc tgttccctta tagaccctgg cttgcaggcc
    13561 ttggtattta cgtaagaaca cccctttgaa ggcagcaaag tcttgattgt tgtcgccatt
    13621 tggagagata gccaacacag gatagccaac tgcatttcgc tccaacacaa atttaccgtc
    13681 tttattacga aaggttccta gtgtgtgcaa gccattgtca gcaatagtag tcatagagac
    13741 attggtatct gtaccaacag tcaccagccc agtaaaatga ttgccgacat aaatctcgtc
    13801 ctttagccct gagctgtcaa aataaaagcc agtttttcct tgagccttta gctcataaat
    13861 agaggcttca acaacaggta ggttttcaaa ggctccctta aagccaacaa atggaatgtt
    13921 gatgttatcc ttgtgctcgt ccttgctatc cacaaagcga acaaagccct ctagataata
    13981 gccatttggc atttgcttag agagttcctc tgtaaagttt gaggcatcta gggtaatggt
    14041 aatggtcttg tgtccttgag caggtacgtc aacctgttct ccctgatagg ttttcagaga
    14101 tcttgaacgt aaggcaaaac gtccttcctt agtatccacc tgatcagtca acaattctgt
    14161 ctggtagcgc agcgacttag cctgattaga caagttatgg attgtcacct caaagcttat
    14221 ctgatcagtc acatttccaa gagaaatact gccatagttg tctttacctg tcaggtacag
    14281 accactggtt accgcggtct ctatattcaa gagccctgct ccctgctggc gtggcgatgt
    14341 ggtggtattg gtcttagggt tgatgtggat ctgagcatta ctcatcagta tatttttgac
    14401 cagatctgct agcttatcct tggcaagctg tggttgaagc gcttctagat attgcttgac
    14461 caaaaggctt gcccctgcaa tgtgtggggt tgccatacta gttcctgact ggctgccata
    14521 gtgatcatcg ttgaaggtcg agtaaatatc tccacctgga gcagtgatgt caggcttcaa
    14581 atagccatct gaggtcaagc cccagttaga gaaatagttc atctcatttc ccttttggct
    14641 aatggcctta gagacctcag catcaaaggt cagagtgcct gttccattgc catttaaagc
    14701 agccattgcc atgccaaatt catgagagat aaaggcagat ggcagcacca tcccctttga
    14761 actcagacgc atggtgcggt tagccttgcc tggctcattg ttaaaaatca agaccccagc
    14821 tgccccgtac tgcttggcct ctgctataat atcgtcgtat ttccgattag gatcacgctg
    14881 caccaagaca atcttgccac tcacttcgcg ttcttggtag ccttcttttg tcaaagcttt
    14941 gacataaaca aatgagtatg gtacatcaaa gccaagacta gtcttaatgt ccttgaaatc
    15001 aacagattcc aaatagatag cctttccatg atttaagtca gccctatctt tcaagccctc
    15061 caccgtcatc agacgctcta taatcacttt gttattaata gacgcaactg aggtaggagt
    15121 ccggcctgct gatggagccc ccactaagcc ataatcagga tttgtcacca acgggtctgc
    15181 atgatctgac ccaaaggcac gctcattacc tgcagcaacg accacagaga caccagcctg
    15241 ccttgccttt tcgatagctg ccatcagggc acgattccca ttcaattgag acccattggc
    15301 cgagcccaga cttaaattaa tcacatcagc gcccaatgcc acagcatctt cgatggcttt
    15361 aataaataag gggtccccag ttcccatcaa atcatgggta aaaacccgca taaacatgac
    15421 ctgagcctca ggagcaatgc ctaaaaagcg ttcgccagct gctgccgcct tgagcccatt
    15481 tccagctgca atgcctgtca catgcatgcc atgcgattca tatttgctgt catcatctgt
    15541 atcttgccag tcaatgatag ttcctcctga tgtgtcatca agcttgatga ccgtttcctg
    15601 aggtgcctct attgactgcg gacggttcct cctaatatca atctgctgca caatcacatc
    15661 aaaatccaag tcgtcaaggc cctcaaacgg atcgtccttt atctccttta ccttatcatt
    15721 gttttccaca tagttgtggg caaagactac cttatcgctt agccagacac cgtactgaat
    15781 gcctgctgct tttttgcgct ggtcaatatc tgcctttgat gtaaacttag cagctgctgg
    15841 atttgtaatg cgcatggcat ggtgactagc gtcaatacca gtatcaataa cagcaataac
    15901 cttaccttga cccttatagc ctctattcca agctccttct gtttttatcc agcggtgagt
    15961 atccatattt actggaggta gctcgcgcga ttcttcttgc tgcttgactg attggttaga
    16021 ttccgttagc gcttccattt cggaagaaac taatccagtc gccattgcct cctctgtctt
    16081 ttcctctgct ttacttgact ggctgtcgat gtcctgagca ttaacagcag ctccctcact
    16141 agcctgagag acagacaata cctcccttga ttcttgatgt tgtcctgctg acacgtgagc
    16201 tgagctaact ccctgctcct cagccacaac tgatcccatc cctgtcagaa aaaggattcc
    16261 gatcaacaca gaaaccattc ctgatttata tttcctcagt gagaagcgtt cttttttctc
    16321 cacttgatgt cctcctagat ttattaaaaa aggttatttt aaacaaatga ttcatttatg
    16381 ttttaatcaa taatgtctaa gctatttaac cattttttaa tcacaaaagc aataagacta
    16441 gaagctctca gtttatgtca ttttttaatc attcaactca ctgaaatgag gcctctcaga
    16501 acctgtctca tcaacagata aggctaaact cagccgctag acttcaaaaa tgtcacacca
    16561 tttttagaca ttacctgtcc tcatacctat aacagaacca agcttccaca gtcgccttgg
    16621 ccttattttt ttgttacaat ataggttaag attatcattt agaaagcgaa gaaaaatgaa
    16681 actcatctca tggaacattg attctttaaa tgctgcgctc actggtgaat ctcctagagc
    16741 cctcttatca cgcgctgtac ttgatactct cgtggcacag gacgctgata ttattgcaat
    16801 tcaagagaca aagctatctg ccaaaggccc taccaaaaag caccttgaga gcttgcttgg
    16861 ctactttcct aatcatctca atgtttggcg ttcatctgtt gagcccgcca gaaaaggcta
    16921 tgccggaacc atgttcctct ataaaaaaga gctcaatccc attgtcacat tcccagatat
    16981 cggagctcct accactatgg acgctgaagg gcgtatcatc accctagaat ttaacgattt
    17041 ctttgtcaca caggtctaca ccccaaatgc cggtgatggg cttagacgct tggaagagcg
    17101 ccagctctgg gaccaaaaat atgccgacta cctagcccag ctcgatgccc aaaagcctgt
    17161 tttggctact ggtgattaca acgttgccca caaggaaatc gacctggcta acccagctag
    17221 caaccaccgc tctccgggct ttacagatga ggagcggctt ggctttacga acctgcttaa
    17281 ccgagggttt acagatacct ttcgctttat tcatggcgat attccaaacg tttatagctg
    17341 gtgggcacag cgcagcaaga ccagtaaatt gaacaatacc ggctggagaa ttgattactg
    17401 gctcacgtca aatcggttga ttgataaggt tagtcgctca gagatgattt cctcaggaga
    17461 acgtcaggat cacacaccga ttttattaga aattgatcta tagactagaa gcattcggac
    17521 aaatcaaccc agacattaaa aaaaaatggc tctgcaagag aaccgttttt ttaatcgctt
    17581 aaagacctag atccttatag gctgttcgat accctacctg caagacctga ttatcctgta
    17641 agaggatcgg ccgcttaatc agcatgccat ctgttgccaa aagctccgct gcctcctcaa
    17701 cgctcagtga attaacctta tctttaagcc caagctcacg ataacgcata ccactggtat
    17761 tgaaaaagct tttgaggcta taatctgaat gctctagcca ttgtttcagc tgctcagctt
    17821 tagggggatt ggccttaata tcaatgatat caacctcaga aaccagggtc tttagctcag
    17881 caagggcttt ttgacaggta ctacactttg ggtattggta aatggtaatc attagctact
    17941 ccttattaac actaatttgc tcgtgcctga gcaaccaggc cttcttttca agtcctccag
    18001 catagccaat caagcgacca tcagcagcca gtacacgatg acagggaata aaaatactta
    18061 aaggattacg tcctatggca ccaccaacag cctgagccga acgacactgc aggcgcttgg
    18121 caagctcacc atagctcaag gtctctcccc atcttatcgt ctgcaattct cgccagacag
    18181 ctcgctgaaa atcagtaccc tgtggagata agcaatcaag catgggatag ggcttcctct
    18241 caaagtaagc gtcaagccac aaacaggctc tttttaacag ggcatgctgc tcctgccaga
    18301 tgggctgcac tttaatccca gcctgaaaat acctttgacc ttcaaaccag gctcctatca
    18361 aagcaacatc agtcgcaacc aaggatattt ttcctaaggg cgattgatac acacactcgt
    18421 acaatggcaa gatctgacct ccccacataa tagcttattc ccttgactat ttattataag
    18481 aaaaagccta gctaaaggca agaaggagcc ctctgacacc acaacaaacg catgaaaaaa
    18541 caatagcggc tctttcaatg ctgccataca atcgttagtg tcaaaagtcg cttactatac
    18601 agctgccccc cttgaaaaac gaagctggaa agacacaaca tgctaaagct gtttcacgcg
    18661 ctggtgcctg attagatgtt cttctaatta aaggccaatg ttctgattaa aaagtcattt
    18721 catgcgctga tacctactca aataaaaaca catagcgtgg ggctagacca atccctcaca
    18781 agtcatcaat agttcgtcta tgagctacac tttatcacat tgggataggc agacatattt
    18841 gccggctcag ttgtacttgc ctgatagcta accaaaagcc cgataagctt tttccgatcc
    18901 tatatcaata gctgtagcgg ctatcctcgc taatctcctg ataagcggct ctttcatggc
    18961 ttttcttaat tttttgatag gctaagcgct cgccatcaat tggtaccttg ccacagtaaa
    19021 caaagcctaa cttttcaatg atatgccgca tgacctgatt atgctcatga gtatctatcc
    19081 gaaaatctgg tccatgctgc ccctcaatga gcccttgcaa aaaggtctga gcaattccct
    19141 gaccagtcct atcactcagc accgccacac gatgaaaggt cacataacgg tggtgattat
    19201 gctgccacct gccatcataa atcttgtcgt aggcgtcctc ttggccatca ataacagccg
    19261 cataagcaac aatctgcccc tcaagcaaag ccacatagcc ctgcccttgc aacacatcag
    19321 cagcaatatc ctgataagca ggatacccat ctgctttctg ccattggctg gagcctgatt
    19381 gggctaaggc agacttagct gaattgatca ctgtcatgat ctgactaagc tcattaggaa
    19441 aagcaagtct aatctccatc gttcacactc acaatctatt ctgatttgat gatgctatgc
    19501 taccgcaaaa agccttacac cttgtcactc tgctagggac acctcatagc ggtatgcctg
    19561 cttctcatct cagctgagta tagcacaata gtcatcattt gacaaaaagc ctcttcaagg
    19621 attgccagca atcatgctat aataaagtaa atcacaaagg agaaccatta tgattaaaga
    19681 attttgtgct gaaaacctaa ccatgctaaa ccaattgacc agccagtcgg tcaatcgtgt
    19741 tgagctctgc gacaatcttg cagtcggtgg caccacaccc tcttatggtg tcatcaagga
    19801 agcctgcgac ctcctacatg acaagcagat tagtgtcgca acaatgatcc gcccaagagg
    19861 aggtgatttt gtctataacg accttgaatt gcgtgctatg gaagcagata tcttaaaggc
    19921 tatcgaagca ggaactgatg ccttggtcat aggcttactc actaaggaca accagcttga
    19981 caccgatgct atcgaacagc tcctaccagc tacacaagga ctccctctgg tttttcacat
    20041 ggcctttgac ctgattgctc gcgaccaaca aatcgcaagc ctagagcagc tcattgacta
    20101 tggctttgta cgaatcctgc ttcatggctc aagcgatacc agatccatct atgaaaacat
    20161 tgaccatatc aagcagttag tcaaggctgc tcagcaccga atcgaaatca tgattggtgg
    20221 aggtgtcaca gctgataact gccaagagct aagtcaacta acaggaacag ctattgtgca
    20281 tggcacaaaa atcatctaac tatcagctca aataaaggaa aagtcactcc ctacaaggag
    20341 gtaaataata gcagcccttc tcgttgaagg ccatacctga gcccttagac taggctccta
    20401 gcaaactaat agtataggac cttcgctgcc tttacatcaa aaaggctgcc gtccagaaaa
    20461 agagaaagcc acacattgat agaaaaccat agctggctct actactatca gtatctatca
    20521 tcagcttctg agctgcctaa aagtttcggt gatcattaac aagtacagac tatttgtttc
    20581 taaattagat cataaaacag acaattatag gaagcgacaa gtgaatcatt attcattttt
    20641 tattgattac tatgatacta taagtaagga tagcgctttc tttttgtctt tgctttgcct
    20701 gactattagg ctctagattt attttttacc atactaatat aagaatcgga ataaataatg
    20761 acaacaaggt atttttataa gctattgcta acgatgttga cactagcatt aggaggattt
    20821 tccctatctg cttgccactc caagattagt aagccctatc aagtcgctat ttttgacaag
    20881 gatcatgtta ggacctttat ggaaaaagct gacagtctgg tgcctgttga gaccatctct
    20941 cgaacacagc acaagctatt tgagcgagaa agctttaagc aggccaagca agggtatttt
    21001 gcaaagacaa gagaaggaaa tgacctcaag gttctgttaa ctcacattga tcaagcaagc
    21061 ctagaagaaa aagtccttca tgctgatggc aatgacgcct acacctctac aactgatggt
    21121 gattactttt acacaacagc tgtctttgcc gatcgtattg actgctacaa gtatgaccgc
    21181 cacttgaaaa aacaggctca caagtctatt ctaaatcaag acaccattaa tgccagcaat
    21241 cagtttctgg tgattgatga cgctctgtac ctgcttgtca gcgctgtaga catcaagagt
    21301 cagcagccca aaactgagct atggaaaatg gacaaatcct ttactatcac tgatcggata
    21361 gatctggacg aaagcactgc ctatctgcgc atggtcaacg tcggacgaac cctttacatt
    21421 acccaggctg ctgatggcat tttagaaact ggagaaccta gacctggtaa caaggtgatg
    21481 acctatgact tagatagcgg tcaaaagtcc tatctcatgc ttcatgtcaa tagtcctaga
    21541 gccatttacc accatgccaa aaccaatgag cttatcatcg aaaatgatca gcattataat
    21601 cctgactttg catggaccat ctaccagcta gataccggag aggagagaac cattcgcttt
    21661 gaggagctag ccggtcagga gacaagctct ccctacttta tgatgacctc aagcaactac
    21721 tacttcctct ttccaaaaag gctttaccga tacgattgta gtaaccatca gatgacctgc
    21781 atcaacctag atcagtacgg agtgacgcac gcccatgcct tgatcgctaa gcccacacca
    21841 taaatcacaa caggcctaat caccactcat tcatctacac cccaatgctt agacaaagca
    21901 gtgtactgac ccccaaaagt tggacacgac atattagtga aaggatttag ttctgtattg
    21961 cacagggcta agtcctttca ctaatatgtc gtgtccaact tttgggggtc agtacacttt
    22021 gggaaagtat gtatgaatct ccagaaaaaa taccttatca actacctcta tatgacaagt
    22081 atgagggaaa taatagttta tttagagata atgcctcacc aaattttagg gcggatgtca
    22141 aagatattac agctacttta gtggctgttt taagtaatgg ttatccaacc gggaaaagca
    22201 gtttttgtaa agactactgt cccgatgaaa tcagggcaag acaattaacc caattagcta
    22261 tttggtattt tacagatggt atttctgaag aaacgttgaa atcaaattat agtctaaatg
    22321 atcttgaatt tcaaggatta aagtatttaa tacaggctgg caaaactgct gggactagta
    22381 acaatcgaac tttagatatc tatatatcta aagatagaaa ttcaaaattt caaaatcttt
    22441 taggttctac cttagtagtt aaaactccag aaaacaaaga gaactgtcaa tgtactaaaa
    22501 tttatataga agaaaatgga aaagatggtt attatcttta catctatgag gatacgaata
    22561 aaaacgataa atatgacaaa aacaaagata aactactaca gaaaaaatac ataaaaaatg
    22621 ggaaagacgg caagcctggc ctaaatggtc aacgtgggcc tcagggcgaa cctgggaaac
    22681 aaggaccaca aggtcctaga ggtgataaag gggaaaccgg agaaaaagga caagatggta
    22741 aaccgggcaa acaaggtgat cgtggtccgg ctggacctca ggggcctaga ggtgacaaag
    22801 gggaaactgg agaaaaagga gaccctggac gtaatggtaa agacggtaaa ccaggtgaaa
    22861 aaggggatcc tgggcaacaa ggcattcctg ggcctaaggg tgatcctgga aaagatggag
    22921 aaaaaggtga acgtggagag caaggacctc aaggcgaacg tggggagcaa ggacctcgtg
    22981 gagaaaatcc cactcctacc ccagatccaa tgccacaacc aatgcctgac cctgcaccta
    23041 aaccagaatc caagccagaa cctaagccga tacctcaacc agaggttaag cctcagccag
    23101 agacaaaacc tcaacaacca aacaagccat caaccattac tagccaacct agcggcaaag
    23161 cactaccaaa aacaaacgac acaggcagct tgataacagt attgggaaca ggcttgctct
    23221 ctcttcttgg actgggcttc ttaactagac gcaaaagaaa acaataatta aagcactatc
    23281 tatagctttt taatcattgg ctatcaaaca aatcacaaaa aagcttatcg ttttactcct
    23341 aacgataagc tttttcgtat tctctattac ttggtcccaa tactattttt ccagctttag
    23401 gctggttttg ttaatccaaa ataatatcag acaatttccg ttttaattaa aaaaaaaaaa
    23461 acgaaactgc ggaagctaat tatcagaaaa tgattcacag cttagagtca ccatgttaag
    23521 ctattctacg gagaagaaag gtttgggaat gactatttct aaactcaaag gagagaaaca
    23581 tgagaaaaac aatgaagaag atgctagcag cctcgacagt ctgcatcatc atgtcgggca
    23641 gctttatcgg aggcgcggca agagtactgg cagagcagta ctatggctat gatgatggaa
    23701 caaaagacgg tggagactgg ccagtatttt tatatgtaac accaacaaat caccccgaaa
    23761 gaaaaaccga taaagagcac tgtgtctatt gctttaacag gttaaatagt tcacctgagc
    23821 tctgggaatc tcaatttaaa gatccaagta agctaggtat aaaactccct atctatgaaa
    23881 agaaagaagg agatgaaagc cttttaagag ctaaatctca gaagcccagt gataacttaa
    23941 cttcaaaatt agttactgtt ctttcaaatg gctatcctaa taagacatta ggtaatttaa
    24001 gtgaagatca aagtcgccga ttaacacagc tagctatttg gcactttact gatggatacg
    24061 ctacaaatca tttcaaagat ggttatcatc taaacaaaga tgaagattca gaattaaaaa
    24121 agttaattga aactgctgaa aaaaacttcc aaactacagc acatacctat agcttaaatc
    24181 tttatgtaac ttcatcatat aattatagta caggtaaatt ttatcaacat cttcttggtt
    24241 ccactttaac accaaaactt ccgaacccaa atccaggacc taaaccacca ggtgggaaca
    24301 atccacatca tttaccaggt gaaaatggtc aaactaaata tccagaagga gaaagcggtg
    24361 aggcaggagc tcctaaaaag cccgagccta aaccagagcc taagccggaa ccaatgccta
    24421 agccagagcc taagccacaa cctgagccta tgccagaacc taagccagat cctcagccta
    24481 agccagagcc taaaccacaa cctgagccta agccagagcc taaaccacaa cctgtgccta
    24541 agccagatcc tgagcctatg ccagatcctg agcctaagcc acaacctgag cctaaaccgg
    24601 aacctcagcc agaaccaatg cctaagccag agcctaagcc acaacctgag cctatgccag
    24661 aacctaagcc taaaccggaa cctcagccta aaccagcgcc tcaaccagag gttaagcctc
    24721 aaaaaccaac caagccatca aacactacta gccagtctag cggcaaggga ctaccaagaa
    24781 caaatgaagc aggcagtcta atgacaggac ttggaacagg cttactctct cttctcggat
    24841 taggcttcct aacaagacgc aaaagaaaag actaagacac taaaagatta tctatagtcg
    24901 tttagttgat cagtatctag tctaatacaa cacaaaagcc ttatcgcgcc ataaatggaa
    24961 cgataaggct ttttaagctt ggttcaaaaa gggtaagaca acttagtcta gcgatgtaaa
    25021 ggcttcatca gcacgcttgc tagtaccatt aaggtcatgg ctgctacaaa caaggccaag
    25081 aaataaggcc aagcctcacc tagattaccg ccattttgga aagtgctgat gatggttaac
    25141 acccaatgtt gtgggagtag ctttccaatc gcctgcatat aaggcggcgt aatactaagc
    25201 ggccacaaac aacccgccag catagaggtt ggcatcacaa tcagattagc caattgactg
    25261 ctttgttgcg catttttaga aaccgcacca atcattaagc caaagcctat agctaacaaa
    25321 ctataaagaa agaaagtcaa caaaacaatg gctgttggaa tgtaaaagct gacatttgct
    25381 accctgagta atcccagcat aatcactatt tgtatcgcaa aggcaacaat accaacacag
    25441 acatagctca gcatgtattg aaggcttgat agccttgata agactaagcg attgtagatt
    25501 tgactggact tatcaagcaa gataccaccg tacaagacac tggtgctgcc tagcattagg
    25561 atcaataaaa agccagttgt tgtcgaggaa acagacttac tttgggaacg atcagctagg
    25621 gtgatttctt tgaccttgta ggatagcttc gtgttatgag ctgaaatctt cttgaaaacc
    25681 tcttgattgc ctgctgccgc atcaccaatg atattgtaat tctccaagag ataattagcc
    25741 tgcgccttaa accattctgt tatttgacta tcagcaatcg aacgtagagc gatcttttga
    25801 gtgtctcctt ttagaacctt ctcaccaaag cccggctcaa tggtcagcac agcctccagt
    25861 gtcttggcct ttaggtattg atcaatagcc ttttcctcta gcctagtata tatctgatat
    25921 tttttattgt gctttaattg cgacacaaac tgcttggaaa cctgactctt atccttatct
    25981 aagatcccaa tcttagcttg acttccccct gtaaagctca aggacaaggc cagcattgtt
    26041 gttagcatag gcaacaggat aaaggtgata tagcttgttt ttttacgtct aattttgata
    26101 aataaggctt taataaaagg aatcatgctg ccacctgctt tctcattctg accaaagcaa
    26161 agaggataaa ggctgttcct ataccaagat taaccattaa ggtaaccggt atgggattgg
    26221 actgcccacc aaaaataaga taaaacaaac tatcattgac ccattttatc ggggaaatat
    26281 tagacagctg attaatcaag gcgctattta aggttgacaa aggaatatag cttcctccca
    26341 aaaaggcaaa gacaggaatg actgcattag acgctaccgt caaaaaggat tgatttctaa
    26401 taccagtcgc aagcccgata ccgatggcaa cagacaaata aactagcgag gccgtcacac
    26461 cgataatctg ccagtcatta gtcccccaat taacacgtaa cacaaatcgg gtaaagacat
    26521 aaagaatggt tagctggact gctgttgcta gcataccacc aattaatttt ccaagcaaaa
    26581 tagcactatt tgagacccct gtcaaataaa tgcggctagc caccccttgc tgacgatctg
    26641 atagcaccag attcatcgct gacataatgc tataaaaggt aatcatggta aacatggaaa
    26701 tagcatagta atccgctgag ctcatgcctt tactggtttg cacagagcta gaggcgatat
    26761 agtctatttt tcttttcttg atgttgctaa tggcttctgg ataaaggtta gcaatcgaat
    26821 cataggtctt ggcgttatcc acatagatat tgacaagcat attaatcaaa tcagcattct
    26881 gttggttaat gctgttggtg gtcacctcaa tgttttggtc gctcttaacc tctagagctg
    26941 ccgtcaaggc gccctcgctg accttttgct tagccttagc gatatccttg gtttctttag
    27001 cttctaaatg aagctcttta tttaacagct ttaaaaacgt gataaagttc ttttgatact
    27061 ctgtttcctt gccctcaagc tgataacgaa ccgtcaattt aggaacagta gctgctgtat
    27121 taaagctgga cttaaaagca aagcttaaaa tcagaatcat caagatagga aaaaccacca
    27181 tcatcaacaa agcagtccga tccctaaaaa tctgtaagct ttcttttttg attaaatgaa
    27241 ataagatcat aacaacccct aatctcttag cttcttacca gtcaaatgca ggaagatttc
    27301 ttctaaattc aaatgcttat gcctaatctc actaaaagca atatgagcat ctgtcagctg
    27361 acgaacaacc gagccaatgt cttcatgttc aatcaggaga actgcttcaa gctcgttatc
    27421 catcagtctc caattgggct tattagagag atcgattgct tggtcagctg cgactgtcac
    27481 catgatttgc tttgtgaaat cagactcata gcgtctttct agctcggcct gactgccctc
    27541 ttcaatcacc tgaccatgat ccataatgta aatgtaatca cataaggcct caacctcttc
    27601 catgtagtgg gtcgtgtaaa taacagtagc tccttgctca tttaacaagc gaatagactc
    27661 taaaatatga ttacgagact gtgggtcaat ccctaccgtc ggctcatcaa agatgattag
    27721 cttaggagaa tgcaccaaag cacaggcaat gtttaaccgt cttttcatac ctcctgaaaa
    27781 ctggcttgga aactggcttg cctgtgattt taaccctacg aactccaagc tttttaaaac
    27841 ctgctccttg agctcacttc cctttaagcc atagagagag ccgaaaagct caacattctc
    27901 ataggctgtt aaatcaggat aaacagcaat atcctgaggg acatagccaa tcttggaact
    27961 aatttttcga atagatttat aagattgctg taaaacagtc acttcgccag cattcaaagg
    28021 gattaaccct aaaatagcat tgattaaggt tgacttacca gcgccattag gccctaaaag
    28081 gccgtagatt ctcccttcct caattgtcag tgagacatga tctattgcct ttttgccgcc
    28141 tcgatagacc ttgacaacat cttttaactc tacaaaactc atatattatt ccttctttcc
    28201 aactctaacg ctgctcttta aaactaatta acagataagt taaggtcaat aaaagcgaac
    28261 caatcaacca accatataat aaggctgctg tcacacacca gacaccaatc acactaaaga
    28321 ggcatagggc tagtagctgc tgtagccagc ctgagtaacg acaggccttg accaaggcat
    28381 agcccaaaac cacaagcgta agacctgcca ctgaatcttt tcctaaaaag agacatagac
    28441 ctaagtaaca aaaagcatca accagtgtga caagacttaa caaaagaaag ctagctgctg
    28501 ccctatctgg tttaaaggct agccaagtca tttttcctaa gagcaggcga ctgtcctttt
    28561 tcagcataag atcaaaaagc aagaccaaaa ccaacagggt cagctctacc aaggctatgc
    28621 tatacaatag cacataacaa atgatttccc agccaaagga tacgcgaccc aaaaaggtca
    28681 gcaaaccatc aagagctaaa gcatcagaaa ataatagaca aacaagcact agaccaagct
    28741 ggattagacc aagcaataga tcaagccatt gctgatagga cattgccctg atgtgcctta
    28801 aatgccatct gactaagcgc cgtcttttat gacttgttag aaaaagggtc actaggatta
    28861 aaaaggatag caatgctagt attatgatca tcgtaccacc ttcttatgca ttgattgaag
    28921 atgactcaag ccttcaaccc ataaattgcc tccaacatga acaagcaaca ccagccataa
    28981 gctctgacta acataataaa tacttccgta aataagacca gtcagtattt tggcgtaaaa
    29041 aatggatctg cccatcagga aatggtttag ggcatagcac aggctggtga tcaacaagac
    29101 aagagcaatt ggcaatcgcc attgaagcca caagatgtta aaccaaatca aacgataggt
    29161 gatttcctca cagcaggcca aaaccaaggg atagcctatc tgtggccatt tttgtgtcgt
    29221 tccgacaaat gataggacta agggaagcca ctcttttttt tgccagcagc ggctaagatg
    29281 taaaaaagca acctcaacaa agagcacaac aaagctcaag ataaaaccaa tgatcaaaag
    29341 acgaccatca ctatgaccta agggcgcttt aataggaggt gacagcaggt aaatccctgt
    29401 taagactagg gcataataaa ccagtacagc tcttaaaaaa cctattagat taaagctata
    29461 gctatcacga ccctggccaa aaatagcctg cattgcgatc gaaggacaaa aggtagccat
    29521 taaaaagcat aggttaaggc attgggtgta caaaggcatt tgtcacacct ccaaactgtc
    29581 tcatgcgtgg atgattagca aatggaaagg caggaatgca catctcaaga agctcaggag
    29641 tgaggacacg tgtcacgtac cagccttttt ctgaggcctc aggaggagta atgtctaaaa
    29701 agacagcatt aggacttact tttttagtgt aggctagtag tgtctttaaa tcctcttttt
    29761 tatctttccc agcatggttt gtcaggtcac taagacgaac ctctcctgaa atcaagggct
    29821 caaaggcctt ccatttaagc tcctgatcct ttggatgagc atagtaaaag acgttactat
    29881 ctaggtctaa aaacaaggga gagtcactct cagcattttg tgttgacgtt ggattataaa
    29941 acaaattata gtaatagcta tagctaatag ctgaagcttc catgattcct cttaacaggg
    30001 tatgcttagg atccaagccc gcctgaaccc caaataagag ataaggacct tcattggact
    30061 tgtttttaag gataatacca aaggtataaa gcggattatc ttctccaaca gtcatgtcaa
    30121 tagggataat ctcataaaga ctgtccttac caagtctagc ctcttccaaa agagctagaa
    30181 tttccggatc atcaataatc actctgggac aaggcttttt agtatgccag ctaagcatca
    30241 tagagtcgat ttgaatatac tcaatcaagc tattacacat ggctgcttcc agcgttgtat
    30301 gagaggctgt ccccgttgaa aagcctggaa tgatgtgctt ttcgcctaca gcctgattgg
    30361 tcttatagcc aacgcaaagc atttgggcag gcacatacat ctccttatct tcaaaaaaca
    30421 tcggacactt aacccagccc aagacatcgt cttgcgtcac cattttatca cacatgatca
    30481 tgtgcaaatc atggcaacgg tcaatttgtt cctgcgtaaa aacctgcaaa tactctaagg
    30541 gcatgacagg atccgtctgg ctcaattcct tataagaagc ataaacaatc cggtctgata
    30601 ataattcccc agcaataaca gtggcataac gctcaatgct ttcacctaag tatttgatca
    30661 aggcttcctc ataatgactg ccataaccaa tgatatgata gctcacctga ctcagctcac
    30721 caataaattg cttgtggtag tcaggcatct gtcctgtcac actctttaag taaacatcat
    30781 gaggatggtt acaaatagga acctgagatt gatttaagat accagttcgg ttaccactaa
    30841 ggccctttag cttatcaaga atatggttga acgaagggta ataatgtagc atccttagac
    30901 ctccttatga ctcttcttga aggagttttt taacaatctc acgtgttgaa atctgttgat
    30961 cctcatacct taattttgtc agagcccctt gtgtctgaga attagacatt ttcaaaatat
    31021 cctgcacctg aatctcaagc gttggcaaat agacacttaa caaacgccct tcaaattttg
    31081 agcttcctgt ttgagcaata ataaaggcct cactgacaac cagattcatt aacacattta
    31141 acaaaggtac ataagaggag ctaacaggct gtgttggcgg caactgctga cttgcaaagc
    31201 gctgataaag cgtgtgatcc tgtaaacgtg ccagcaccct tctctccaag ctatcaaaat
    31261 cagcactatg aggaggattt aaggtacaag catggataaa cggcccatca acaaagccaa
    31321 gcaccaattg ttttttcaag gccacactga tttcattaag gtgacgcagc atcataatat
    31381 tcaaccggcc ttgacaaata acaatactct gatagtctgc gagcttctca gataagcact
    31441 tcatgttgcg atggtgctcc agagcatcta agcgagaggt aacatctgtt tcttgaatga
    31501 gcatttttag ctcatcgcta gccacctgaa ggtttaagtt caggtgcttg gccagcagct
    31561 cagcagattc attgacatag cttgaatcac tgataaataa gacaggtgca gtatccttag
    31621 cctgtcctga ttcagctatg aaatgataat tgcctgttaa gaccttcatg atattttctt
    31681 caagagcata agcgtcttca agcatcaata ggtcgttata atacaaggct gtgatgacct
    31741 ctgacaattt tgcaaataag tcagactcta gtgttttttc gtaggtatca gtatcaataa
    31801 ctttcccgtt aaaccaatcg gagatgatac tgtagtaggc ttcttttaag gcttgtggct
    31861 cttgtgcaat gtctaaaaca gcttcattaa aatcccatag gccttttcta aagcaaaacg
    31921 tatcgtcaaa ttgcacaatg cgaacattgc tatttaattg atatttcatt gagactcctt
    31981 atttccaata atcgtcatgt gaatcacatg ctgggtcaag ccatccaagc ctagcttttc
    32041 ttggaggtat tccttattgt accctccaat atcaacactt ccatatacca aagctgttga
    32101 gaccaattga acattttgag caatctctcc agcttcaata aaggcataag cagtagcttg
    32161 atttccatat ttacgtgtgt ttttgatgta ctgataaaca tagataagaa tgacattgca
    32221 gttttcggca gtgatcggtc cgtattcggc aaaggctcta atatcctcct gatcactaag
    32281 atgatgacac ctcagcgcgt gctgataagg aaggtattca taaaaaccgt ccttgagtgt
    32341 ttctacgttt cttgcataga aaaataaggt gatggggtac agacccccac cagaagcaca
    32401 atttcttaag gctactgtct tagtcatgcc ttctttgatg attgcctgag agctgacacc
    32461 acaagcataa taaagcaaat cagccaaatc ctgcaaaggc atctcctcat ctataaactg
    32521 cctatgactt ctccggttgg tgatacaggt tgatagggct gctgagacct tcttagcttt
    32581 aggaagtgct atcgtgtttg ccctatcctc aaaatagtca ctatttgaaa aggtggtcac
    32641 tgcagaatcc gtaaaaaact cagccacact ggtcttaaac cctaggtaat tgttattagc
    32701 cttgtaattc atcaaaaacc gttggctaag attgtctgtt tcatcaggca tcaaatgctg
    32761 tgccacaagc tgttttgatg tttttaatac cgtttgatga tgataggttg ataacgataa
    32821 gtgattggta ttaaattcaa ataactgtcg tgcttcttct cttgttaggt cactttggtt
    32881 atccgaacgt tgtttttcct tagaaaaaaa tggcataact gtcttcctgt aatatattaa
    32941 taaataatag taattagcag gtaccgacta gtacctgcta attactacaa gacgttgaca
    33001 tcaagctgat tgtcttcgtc tcttgtcatg taacacccct atccaacacc agctaacacc
    33061 atcaattaca aactgtaacc ttagtcgcta gcaaactaat gattgtgacc tagctattaa
    33121 ctattaaata gaagtattaa agtttacgct tttggctcag ctgcaccata attgttgttt
    33181 atggtagtat tgccccatga agctgagacg cagcaacaac aagaacagca acagcagcaa
    33241 ccaccaggag caacttgagt tgtttctgct acactagtag ctaaaatatt tgaagcaaat
    33301 tgtaacataa tgcttacctc cttatatcgc ctgatcggta aaacaaaaca ctgataagag
    33361 ttaaatgaga atacctctca actgatagca aaagcaatca tgagcaggta tccagcaaca
    33421 caaggctagc tattttgtat cgcccttgtt aaagtgacca ttcaattctt accaactata
    33481 ttatattaaa attcaagaca tatgtaaata ctttctttaa tattttctta caaaaatgtc
    33541 attatttttc cagaaaggtt agcttattga gcttgacaaa gtcttaagcc tatctcttta
    33601 atggcattta taaactatca gtctttttaa tgaaacgcat taaaataggt agagatatta
    33661 ttatctctac ctaaactgta ttgatgagac agatggctag tacctcacaa ttaaccattt
    33721 ctaaaaataa tgactctttt gtcgaaagac ctaatgatta aagctatttg tctttgttta
    33781 tctttttctc attagtaaca ttaaatcatg gcaaaatatt tatattcatt taataatcaa
    33841 gattccggat catcaagtga ccgtccatgc agaccttttt cgcgctgcac ctgtcttaat
    33901 ttctcaggag taacatcgtt tccgtcttca tcaacaatct taatgccttc aatgtgatgg
    33961 cgcactgagc ggcgatagcc ctcaatgtat tcctcacgca gcttggcctg ctctaccttt
    34021 tcaggaccag tcaagccaac tgtttttttc ttttttgcaa gctcgttaat acgagcgatt
    34081 tttttaggat ccataaatca catataaggg ctgcaccaaa agcagtgagc agctgatgag
    34141 gcttgatgat gggctagaca gcctctttag gaccgttact aggacctttc aagtcctttt
    34201 tcaccagctg tgccagcaag ggctgcctgc aaatggggct gcctctaatc ctttctcttt
    34261 cgtttgtgac atagagtact gcactctttt tgtctatatc taaggctgtg ccagcagctg
    34321 cttagcctta tgcttctgcc aagaaggctg tagcaagctt cttgtgaaaa gctaaaatcc
    34381 atgctcactt tactaacagt gttcctgatg cttttattga ccactgacca gcacagctat
    34441 tgctagcaaa gctagcccaa gacgatatct cgtagtaagc aagaggactg atttgactaa
    34501 gtatcaattg cttgataagt cttgagtgct tagggaagga cttatcccaa ggcaggtaat
    34561 cagtcaccta tatcatctag ggaatacgaa cagctaacac agggcgatgt gcttaatctt
    34621 acacagcgaa ttatttagta tttaatcggt caaaggccgc aatggtctct acctttttaa
    34681 ccagctctgc taacagcgct aaacggttac gtctaatagc ttcgtcctct gtcatgacca
    34741 tcgtatggtc aaaaaagtca tcaataactg gactaagggc aaagacctga gctagctgtt
    34801 ctttggctga tccagatagc actagtgaat caacagcctg tgccaaagcc ctttcgtagt
    34861 cattttcaaa gaggctagca tcaatcagca cagcgtcaac tgcctttttc gctagattaa
    34921 agacgcgaga cagcgactcg acagcaggct tgtaggtgtc tagctggctt gccgcagcca
    34981 gagcctccgc tcttgctaac agttctggta caacaaagct tgagctagcc agaactgctt
    35041 cacgtatatc ctttggaatg gctgagccca tcattttatc cacacgtgca caaataaagt
    35101 ccagcacctc agccttatgc tgataggtca agctatcaaa tgacagctca tataggctat
    35161 caatcagctt atccatagga atgctccagc cgaaatgctc aagaattcgg acgatcccct
    35221 gagttgcacg acgtagggca taagggtcat ttgagcctga cggtatcaaa ccaacagaga
    35281 aaaaggacag cagggtgtct agcttatcag caagagcaag gacagcacca acctttgttt
    35341 caggcagctc tccttctgcc gaatttggca aataatgctc acgaattgct gttgcgacag
    35401 cagcagcttc gccagttaaa agggcgtatt tctcccccat aatgccctgc aactcatcaa
    35461 attccccaac cataccagtt agaaggtcaa atttataaat ctgggcagca cgagcgacag
    35521 cacttttttc tgcttctgag agcccagcct ggtcagcaag aaaggctgca ataaccttgg
    35581 tccgctccat atgctcagcc acagagccta tcttttcatg gaaggtcaca tgagctagct
    35641 tagcaaccaa atcttcaata gatagctttt gatcctcacg ccagaaaaat tctccatctt
    35701 caagacgagc aacaagcacc ttttcattgc ccttaatcac attttgaaga tgcttagcat
    35761 taccgttacg aacagaaata aaattcggca ttagcttgcc agcctgatca cgcacgacaa
    35821 aataacgctg atggttcttc attgaggtta ctagaacctc ttctgggatt tccaggtact
    35881 tgggatcaaa acttcccatg aaggcagttg ggtattctac taggttgagc acctcattta
    35941 agaggtcctc atcaatatcc acctgaacct tttgctctgc ttcgatggct ctgatttgtg
    36001 ctatgatcat ctcttgacgc tccttagcag aggcaatgac aaattggctg cgcaggtcag
    36061 cctcatagga atcagcactt gtaatgctag tctcttctcc aaggaagcga tgtccgcgac
    36121 tgatacgtcc cgaatgaatg tctaaaaagt caagctccaa aggctcatca tctaacagta
    36181 caatcaagct atgcaccgga cgaatatagt caaagctatt gttagcccag tgcatgctga
    36241 ctgggaaggt caaggaagca agaacctctg gcaccgctgc taagacgtcc ttagcctgct
    36301 tgcccgcttc atgcttggtg acataaacgt attcctcacc tttgacctct cggaattcga
    36361 tgtcatcaac agtcaagccc tttccacgaa caaagccctg agcggctttt gaaaattgac
    36421 catctgcgtc aagagcaatt tttttagagg gtcccttaaa atcctctgtc agatcagtct
    36481 gctgatcagc taagcccagc acacgcactg ctaaacgacg gggcgttgaa aagccttcga
    36541 ttgcgtcata gctaagccga ttggccttaa gaaaatcagc catacgttca acaagctgct
    36601 tttcactagg tgtgacaacg taggcaggaa gctcttcaag accaagttct acaagtaaat
    36661 cttttgtcat cattaaaatc ctatgggcat caaatctaaa agagaagacc aaaccgatcc
    36721 tagcatgcct tgggcaagct tggacgatcc tttgtctaca agatttgtcc catctttctt
    36781 tcctttcttc aagttatggg gtaggtttag gagaccaaat cactagctcc taatcctgca
    36841 agcctgctaa taagctgcct gttagacaag atcacttagc agaaagactg agcttaacag
    36901 gactagtcat caggccttta agtctcatcg cttttaaaaa gcacctacca gataggtaag
    36961 ctgctagcag caactagagc ttacaagatc atacaagctg cattgactac aaggaactag
    37021 tttagatcca gctgcttagt cctctgccag caaggctact cggctagcat catccaacaa
    37081 tgggaagcca agctttttac gctctgcaac aaaggtttta gcaacgctac gagctaaatg
    37141 acgaatccga gcaatatagc cagcacgctc tgtcacagag actgcaccac gagcgtcaag
    37201 caggttaaag gtatgagagc atttcaagac atagtcatag gctgggtgga caagcccttg
    37261 tgctaaagca cgctctgctt ctttttcaaa tatctcaaag ttttcaagca gcatgtcctg
    37321 attggatacc tcaaaggaat acttggaatg ctcatattct ggctgaagaa aaatctcgcc
    37381 gtacttaaca ccaggtgccc attcgatatc atagaccgaa tccacctctt gaatgtatga
    37441 ggccaagcgc tctaagccat aggtgacctc tgctgtcact ggtgatgttg ctaggcctcc
    37501 cacctgctgg aagtaggtaa attgtgtaat ctccatacca tcaagccaga cctcccagcc
    37561 aagtccagct gagccggttg aaggattttc ccagttgtcc tcaacaaatc gaatatcatg
    37621 ctccaatgga tcaatgccaa gtctttcaag agattgcagg taaagctcct gaatattact
    37681 tggagaaggc ttcatcacca cttgaaattg atggtgctga tacagacgat tgggattttc
    37741 gccgtatcgg ccgtcagcag gacgacgaga tggctccaca taggcagcat tccaaggctc
    37801 tggaccaata gcgcgaagga aggtataagg actcatggtt cccgctcctt tttcattgtc
    37861 ataggcttgc attagcatac aaccttgatc attccaatat tgctgtagcg tcaaaataat
    37921 ctcttgaaag gtaagtttgt tactcatgat ttcctctttc tattttttat gtcttgtcgc
    37981 aggcgctaac caagagctgg ctatggcttg actgctggtt ggctcttaaa cagcttttca
    38041 aagagaaaaa ccgcgcctat agccacctac acctaaaggc ataggggcgt caaaacgcgg
    38101 ttccacccta atttattact tcatttgatc ttgttgataa acagatgtca agcaagctac
    38161 aaacacctga gcctactctt tagagaaagc gccaaccagc agtaccatca ctcggctctc
    38221 accagccccg agctcgcttt agatcagaaa cctgctattt tctttcctat tggttagttt
    38281 atcacaaaat cctatgattg tctaatcaac tattatgatt ttggacgagt tccgtttgga
    38341 ataataacct cagacaagag cctattttct tcacgaatgc gcagataaat cacaataata
    38401 tagcaaggga aaagcagcat tgccgtaatc tgagcatggc aaagcaaagc aataccaacc
    38461 agctctggag caatgtttaa aaagtaattg gggtgcttaa cagtcttaaa gagccaatga
    38521 tcgacatatt tatggtcctt tgccagcatc agcttcactg tccaaatatc tcccaagatc
    38581 cgagttacct catatagcac agctatcgaa aaaatcatca gcagcaagcc aagaaagcta
    38641 atgccatcaa acttaatctg cttgagcaat gcctctgtca cagcaaagac ataaatcatg
    38701 atatgcagca gggtcaaaaa cttagtgttt tgcgcaccaa attccttgcc cccattagcc
    38761 aggatagcct tctcgttttt gatcgatttt tttaagaata ctaaacgaat agcaaacatc
    38821 aagagcatca ataacaggat aatcaaagta agactccttt attctagttt aatctgtttc
    38881 tttcacgaaa cactaattaa gattatagct aagttacaca gccttgtcaa accgttttca
    38941 aaaaaaagat gtctttcttt gatctctaaa aacaagaggt cgtcacacag caccatcaag
    39001 agacctcatc aaagctttaa ggtcgtacca aatcaccatc aaaagacagc tcctagactc
    39061 agtcaattca cgagcagcaa gcagcaccca agaggcattt tgcaggcctg acctacttcg
    39121 cctgtcgtaa acacaaatcc tcaatatggt aaatagcgtc acattgcgct gcaacctcat
    39181 cgctgtgtgt tgccattaag acaatcatat cctcagtctg acaagctctg atggcttgta
    39241 agacctcctg ctcagcctca atatccaggg cgcctgttgg ctcatctgcc aataacagct
    39301 gcggtgtttt gaccaaagca cgagcaagga ccactaatgt agctcactta atccctgcag
    39361 ctcttgctaa aagtccttgg tatcaggatc tgggatagct gacatacccg gcaggcaacg
    39421 aatgcgctct gaatcctctg gactaatctc acaatcaaaa atagccatat tttctactat
    39481 gcgttccttg tgcaccgact taggtagagg aataaagccc tcagcaatag accaagcaag
    39541 ggctagctga gccactgtct tgttgtactt tttagccaat gcctgcatgg tatcatcggc
    39601 aaatatctct ccttgtccta atggacccca ggcctctagc aaaatgtgat gcctgcggca
    39661 ataatcaacc gtctcttttt gatagcagcc aggcgccaag cgaatctgat tgactgctgg
    39721 tgtaatggtt gctgtctgtt taagagcctc cagatggtga accataaagt tgctgacacc
    39781 aatcgagcga accaagcctg cttcaacagc ctcctccata taagaccaag ctgctgcatt
    39841 ggctgcttgc cagcaatccc taagagcctt aggatttggc caatgaatca gataaaggtc
    39901 tacatactct agtccaaggc gctcaagaga ggctgctaag gctgccttag cgccatcata
    39961 gctatgagca tcattccaga gcttagtggt aataaagagt tcttcacgag gaacgcccga
    40021 atcccgaatg gcctgtccaa cacttttttc attgtgataa atggcagctg tgtcaatatg
    40081 acgatagcct gccttaatcg ctgctagggt ggattggtag gcctcctcac catcagcagc
    40141 cttaaaggtc ccaaagccaa gcactggaat agcaagacca ttagccattg ttactgtttt
    40201 aatcatatct aaaacctcct ttttcattgt agcacaatga taagcaaagc aaaaagaatt
    40261 gagctgatca ccagcccaat tcctttgctg tattaagcct caaaggcctt ttgaccattt
    40321 aggtaggttg ctactaattc taagtcctta tcaagaacaa taaagtcagc agcatgacct
    40381 gccttgattt ggccacagac atcttcaata ccaaccgaag cagctgggac gtaagaggac
    40441 atgtgaattg cttctgctgg acttgcaatt ccccaggcaa caacattttt aatgccgtcc
    40501 tttaatttta agatagagcc tgctagatta ccactatcct tcaagcgagc tgtgccattt
    40561 tccacaataa ccggaaactc tccaagcatg taatcaccat ctggtgaacc gcctgcacgc
    40621 atacagtccg taatcaaagc cacatgctca tgaccctttt gctgcatcaa aatatcgcaa
    40681 gcaacaggtg agacatgatg accatcgcag atcagctctg caaccgttcc aggaatatta
    40741 taaacagccc caaccatacc aggctcacga tgagtcaagc cacgcatccc attgtaggca
    40801 tgaacccaaa cactagctcc tgctgctact gcctttttag cctcagtata ggtaccattt
    40861 gagtgaccta aagctactgt gacaccctgc ttggtcacct cagagacaaa tgcttctacg
    40921 ccatcacgct caggagccaa agctattttt ttgatcaagc ccttagctgc tttttgccaa
    40981 gctgcaaatt cgtctaagcg aggatttttc atatatatcg ggttttgggc tcccttgtat
    41041 tcctcagtga agtaaggccc ttcaaaataa atcccctgaa tctttgctcc tttgacctga
    41101 tcggcaacag aagcaacggt tgcagacacc tgctctagat gctcaaaggt tgacgttagg
    41161 gtagtcggta agaaggaggt cactcctgtt gataagagac cctcactgat ggcatggaga
    41221 ccttctgctg aattatccat cacatcagca ccagcatagc catgaatatg agtatctaca
    41281 agtcctggtg ctatttgata gcctgtataa tcaataacct ctgcctgatc atcaacagta
    41341 gccgtccaat aaccaaatgt gccattattt agctccaaat agcctgctgg ctttacctcg
    41401 ttggggtaat aaaagcaatc tgctttaata tagcttgtca tcttttttcc tccctttttc
    41461 gtttattata cgccttaatt cttattttgt aaatggtata taccagtcct tctgttaaaa
    41521 agaaaaacct gaatactatt tcaagttttc ccttttatta gagctgtcct gaaagtactt
    41581 tctcagctag atttagggcg tggtcagtga tacgtgtgta atgagatata atgtcaataa
    41641 aattaatccc tgcctgtgct gtgcattcgc cacgattgag gcgttcgatg tgtgttttac
    41701 gcaattgacg ctctttttgc tcaatcgtcc tatgacgctc aacaatagac tgggctagag
    41761 ccttgtcact atccacaatc gccctaatcg catctaaagt taaacagtgg gtcaggtgat
    41821 acatttctgt taattcacca cgtgcagctg ctgaaaagcc aatctgcttt gctgtaatcc
    41881 cctcaatgag agtcgctaac gactcagagt ggtcaccaat tcgctccaaa tcacgagacg
    41941 aatccaacag acctgctaaa acctcatttt cactaggact aagggcttca ttggaaatat
    42001 caacgaggta agtggtgagc tcctcatcaa tcgtattgac cgccttctca tatcgcctca
    42061 ccttttcgcc aaacttgtct tctgctgtca taatgtagct ataagacgcc tcaaaagcct
    42121 gaatagcata ggaagccaga tgtaccaatt ccttgtgggc atttcccaag gcaatagaag
    42181 gagcctgagt gattagtaaa cggtccaaat acaaggcttc atatttgacg atttcgtctt
    42241 cacctggaat taaggtggtc acaagctttg ccagagtgtt gataaaagga agcagcaaca
    42301 gggtatttgt gatgttaaag gtcccatgtg aaaaggcaat ggtcatctca ggtgacaggg
    42361 ccaaaacaga ctgaagccat agcataaagg aggtaaatgg catcagtaaa atcataaaga
    42421 tgaccgtccc aataacatta aaaagaatat gagcagcagc aacacgctta gctgcaatat
    42481 tagagccaat agctgccaaa accgctgtga tacaggtacc aatgttagag ccaagcaaaa
    42541 taggaatcgc accctgcagg gtcaataggc cacccgaaaa aagcccctgt aaaataccaa
    42601 taatggccgc cgaggattga atcagcatgg tcaatgctgt cccgataaaa acaccctgaa
    42661 agggcttgtc tccaagcgtc gctaggtaat gctgaaaggc tgagactgat tttaaaggat
    42721 ccatcgcatc acccatgagg ttgagagaaa agaaaattcc tcctacacca aaaatgatac
    42781 gacctaggtt attgagtttt ttatttgacg tgaaaaagag acaggctgct ccaataaaaa
    42841 tcatgggcag ggcgtaatct cccagcttaa aaccaatcaa aaaggaggtc actgttgttc
    42901 caatgttggc ccccatgaca ataccaatcg cctgctgtag ggttaaaagg cctgcagata
    42961 ctaggccaac tgtaatcacc gtcacacccg agctagactg aatcaaagca gacatagcta
    43021 ttccaaccaa gataccaaag aaggggttgc ttgtgtactt gtcaatgtaa tacctaagct
    43081 tatcacctgc ggcctgctgc aagtcgtctc ccatgtattt gatactgaaa agaaaaagac
    43141 ctaagccctg tactgccccc caaaaaatga aacgcaatgt cttgccaatt taccgacaca
    43201 atattgtcct cactcgctta tttattctct tctattttaa tgtatttatt cagttatcac
    43261 aagggttttt taatcctttt aaatagtgct catttagaac ctattttaga gccctagtcc
    43321 tcttttcatt ttcctatatt cagggtataa tagtgctact caagcgacaa tgatttcaaa
    43381 ggagatacca tgagaaaacc gacaaaagag acccactacc tcatcattag cttgcttact
    43441 attgccattg caggaggggc ctaccttatt tttagtagcc tctctccaaa gccagctacc
    43501 attaccaccc aatctaaggg ctatgagctg ttaactaagg ctcaagcatt agtcaaggag
    43561 gccgaagaca acccaactaa agaagctatc gcaaaggctc aaaaagcaat taatcagcta
    43621 aaaaagaccc agtctaagga ggaattacag gctcgactaa cagctatcag cttaaagcac
    43681 aatcaagaag acgttgctat caaggtccta aaggcagccg aggacaatcc aagccctgaa
    43741 cttaaggagg ctgcacaaaa agccattagt aagctctctg atgaggctaa aaaagctgcc
    43801 ttacaggcta gacttgacgc tattggactt tcaaagccta gcactgcaca gcctgagact
    43861 gcaacaccag cagcagaaaa aaatatagca ccagctcctg cggctccaca aataaagcat
    43921 accacaccgt cttctggggg aacgacgcca gcaccgaacc ctaaacctag tcctaagccg
    43981 aatcctcagc ctagtcctag tccagctcca gagaacccag agccaacgcc tagtcctaac
    44041 cctcagccaa atcctcaacc agaaaccaac acacctagcc ctcagccacc tgcaacagag
    44101 caaagtgaaa acactgctcc agcaggacaa aactaagaaa gggcagccag agctgctgta
    44161 gcttagttac acttcttagt acaggcaata agggcttagc tactgaaata atgctaaact
    44221 tacgactaat aagctctctg ataaaaagag gctttaggtg attaaaaaca gctggttcta
    44281 aaaggattcc agctgttttt gtgcttctta attgattttg aggtaggaag agaagggagg
    44341 cttaatcaag tcgataagta atcccatatc ctctcctaac tctctatcag cttggctatg
    44401 attatagagc ggctcaccct tacgcgcttt ggtgattcgt catggatatt ctgactggct
    44461 tgaccatttg agttttttcc tcagtgtcac tccctaagac ttttaaggga ctgacgaggt
    44521 gattagcatg cacaacaaaa agcccttaaa cacaccttta aggaccttgt attcagctta
    44581 atgcctctat agtatcaggg atatttgtta aggcagctct cagctaaaga cttgtgataa
    44641 agacctatgc ctatccgacc actagctaga gtcaagctgt gcatagctca gcctctatga
    44701 ctaacagaaa ccagaggcag cgttagatca ctttgcttag cttaaacctc atagcccatg
    44761 agaagccctt cagcttctgc atagaagctg cataggcctg aggctgggct ggtttgaatc
    44821 tctgcttctg ggtaaatcgc tctaattttt tccgcaattt gctcacagat cttagggttt
    44881 ttggcgtggg agataaagac tcggcctcct ttatagcctg ccttttgaat ctcttctaaa
    44941 acagctgaca ctgccttttt ttgacctctg gccttttgaa gcagctcaag cgtgccttcc
    45001 ttacttgcct gtcctaccat tctgatgttt aataagccaa tcaccttacc aatgagctta
    45061 ttcagacggc catttttaac cagattatca accttggcca acacaaaaac aagcctggtt
    45121 ttttcctgat aagctgtaat tttctcaaca acctcatcaa aagaaagccc ctgattgatc
    45181 aaccgctcta gctctaacac aatcaaatcc atctcaccac ctgctgacaa agagtcaatc
    45241 acatggatat tggcattcgg attttcctca agcaagtcat tttgagccaa tctagcacta
    45301 ttgtgactgc ctgagagcgt accggtaatg gtaatggcaa tgacgttatc tgctcccctg
    45361 taggcttgta aaaaagcatc aggacttggg cagcttgagg ttgctggctt agaggactga
    45421 tacatagtct ccatcatttg atcaatatct agaccatcat catctctaaa aatatctgaa
    45481 ccaatctgta gggttagcgg cacacgctca aagcgcaggt gattggattg gctttttagg
    45541 gctctaatat cgcagcctga atccgataca attttccagg tcattcgttt tcctcttttc
    45601 cttcatagtc tgttttggtt gacaaagtaa gcattttccc ataaaattat atcatcacta
    45661 gctagacttt tgctagctaa acgacatcag atgtaacact tgaaaggtat ttgtaatggc
    45721 tggtaaacca atttctaaac agtcccttca aaatttagcc cactgcaatc aggaatccag
    45781 acggttaaca cgagaagcta ttgaaattgc tctgcttagc ttactagaaa agaagccctt
    45841 aggacacatt accatttcag aattggtagc tagagctggg gtttcaagaa atgcttttta
    45901 ccgcaattac agctcaaagg aggatattct tgagtgtctg ttgacttctg ttatcagacg
    45961 tatctttcgt ggactgaagg cctttgatct aaagacacag gcctatcagg catggcttta
    46021 tctgtttaca gaggccaaaa aagaagcgac gctacttagt attatcttta accatcacct
    46081 gcagcagctc ttgacgcaga tggttaccaa gcgtttgaga gcctaccaaa agtggcagga
    46141 aaaaaagctg tctcactacg cactgctctt ttggagcaac gctattgtct cagtcctttc
    46201 caattggatt tctgatgata tggttgttcc tgctgaggag atggctgcta tggggctgcc
    46261 cttattagcc tagttgtctc tagatcacct atagctccta gacaacttcc caagaaacca
    46321 agcttgcagc atcagacagg acgcttggct ggcttgactt aagcactggc actgcctacc
    46381 aagatatgta ctagccctac tacaggcaag gtgtgacttg tcgctcgctg ttgtgcagag
    46441 gcttaaaggc tcttacattt agctggacaa taaaaaaaga ctgaagaggc tggctggatt
    46501 agcctgctct tcaatccaga acctcctttg ttggaggttt tttcgtgttt tatttttcag
    46561 tcgatctcac acacctaggc ttgtggtgtt ccaagacagc tcagctctag tcaacacctc
    46621 taaaactgag cttatcatct ctagcttttg gaggcctttt ctgacgggct ggtttgactg
    46681 tgcttaagag ccctttgtca atgcaaattg attaatggca tgggccacgc ctgcttgatc
    46741 attggagagg cttaccttgt cagcgacctt tttaattgcc tcatcagcgt ttcccatagc
    46801 gacacctaag ccagcatagg ctaacatttc aagatcattt gctgcatctc caattgccat
    46861 cacttggtct gggcgcagct tcagatcagc ggttaattcc ttcagggcag aggccttggt
    46921 cacacactcc ggcattacct ctaggattgt ttcttgactg cgaaccacac taaagcttgc
    46981 gctgagtttt tctctaacaa gagcctcaaa agtatctagg gcagcctttt ctcccatgta
    47041 catggcctga aatatgattt gactgctgtt ggataactga gataggttag tagcctttac
    47101 ctttgtaaaa accaaatcac catcagcctg aaccatatct ggaaccttgc tatctatcac
    47161 aagataatca cgctctccag tcagggtgag gtaaatatct gaaaagggct gagacagctg
    47221 ataaaggtgc tcaatagctg aaaaggtcag gctttgataa tgtagcagct cccagcttgg
    47281 gctcctatag gtgctacagc cattgtttaa aataaggtac tcctccttat cactcaagcc
    47341 taattgctca aaatacggcc ttgtcccaga ctgggggcgg cctgtgcaga gaacaacttt
    47401 tatcccctct tgtgcagctg cttggatagc cttaatattc tcttttggaa tgtgcttttt
    47461 gctatcaagc agagtaccgt ctaaatcaat tgctataagc tgaatcatcg tctcagtcct
    47521 ctttccattt tatcttaggt aggtgccatt gtcttttgtt gccaatcata cgcatgactg
    47581 tcaataaaac aaccagcaag tagcattcaa catttgaagt ggccagctta aaataaagca
    47641 caagtgctgc tataatagac cagccagcat aaatctcact tctaagaaca gttggcttac
    47701 ggcctgccag gacatctctg accacacctc cgcctgcccc tgtaagaacc gctgctacaa
    47761 taacagcgct taagggctgg gctagtcgaa cagcatgtag agccccctga acactaaagg
    47821 ctgcaagtcc gatagcatca gtcagcaccg ctgctctcac ccagccctta gccacaagct
    47881 taggaaatag catgatcaga ataatagcta taaaagcgca ggcaaattct ggtctttgtc
    47941 cccacaaggc ttcaataggc agcccgatca gggtatttct aatagcccca ccaccaaagg
    48001 ctgtgacaaa gcctagaata aaaatcccca gaacatcaaa ctcctcctcc atagcgacaa
    48061 tagcgccgga caaggcaaag gctatcgttc caataatgct taaaagctcc cacatatcaa
    48121 ttgtcataac tcacctaatg cttcctaatc ccctattagt ctaccatctt tttaatcaaa
    48181 atataagtca aaataagagc aaggtcctca aaaatcctac tgatgacctg tttttgtttg
    48241 caccaaagat ttagccccta tataggctag gctcctagta gcaggagtta ggagcgatag
    48301 cttgccaaat tcacagcctt gttattttcc atgagaaagg gctctgctga tgtcttggtt
    48361 tgataggtct tgtatttatg gtagaggtat tggtagcaat cctgtttttg atcaaagagg
    48421 atggcttggt agggctcttg gaaggacaat ttctcaacaa acagatactt gctcttatac
    48481 tccactagca ctcccacatg accaataaaa aggtaatcac catctagctg atcgtgaatc
    48541 acaacagcaa gcattttggc tgggccatta aagctaacag ctgagaaatg ctcttgcata
    48601 tgcttggcat gcacctgaat atccttggtg gcttccgttt tcactcttga aaacagctgc
    48661 ttaaagcgct ctgtctctgc ctgtgtaaag agctggcttg tggtaatggc gtcctcgtcc
    48721 ataaataaaa gcgtatcatc actgctggta ggcgcaatcg tcatgctatc ctttagaagc
    48781 ataaaggtgt tgatccggca attagttcca atgaaattgc cttgcttttg cgaccacaac
    48841 tcatcgattg ctaccacatc atagtcaggc tgcttctgat aggtaaaggc ccctgtcaag
    48901 cctgttttgc caactaggct attatattct tgtacaccag ccataaaggc attgacatta
    48961 gcttccttca gctgatgtga tagggcagcc ctgacctcct gctggctctt tgcactgttc
    49021 atgttggata ggaaaagacg tcccttctta gcctgtggct ctttttgctc ctgcttgggc
    49081 tgatcagact ggtgagaagc ctggcaagcc ccaagagttg ccgtagcaag gattagcaaa
    49141 gacatcatta cttttttcat cataacctcc tttttaatga gtcattcaag ctggtactct
    49201 ccatcatcac caaatgagat tatcagcagc tggcagctaa tacgaggttg ctacaaccca
    49261 cttgttatct ctttatgtca tgacctcatc gttaccagta tagcataaaa aagaaaagca
    49321 ccagctcttg aagccttgca gcccttgtgc cggtgctttt cgttaggaga ttacactgaa
    49381 atagtttttg tggtagctag ctgctgatac caataagcgc tttttttagg gtaacgcttt
    49441 tgggtttcaa aatcaacata gaagaggcca taacgcttat catagccatt tgaccaagaa
    49501 aagacgtcca tcaaggacca gataaaatag cccttaacat tagccccagc accgatagcg
    49561 tctgcaatca cagccaaatg ctgcttgatg taatcaattc tagcgtcatc atcaatcctg
    49621 ccatcaatac aggtatcctt gtagccaagg tcattttcag tgatataaat ctttttatag
    49681 cctggatagt ctgccttgat ccgcatgatt tgatcgtaaa gcccctgtgg atagatcatc
    49741 caatcccagt ctgtacgcgg cacatcaaca tcaaacacgc gttgaccaac cccctttatc
    49801 tgatatttgg agccgccttt ttctcccttg ccattatgaa tgatttcggt ctcaccatgg
    49861 ctaataataa gccagacttc tcatcacgta ccttagtggc tggcaggcca tattcagggt
    49921 ctagcaggat agaggaggca tagggggtta gctcctctga taccagagcc tttagggctt
    49981 cgatttgcca aggagctggc tctgtgtctt ggtgggctgc catcatgcgc tttaaagccc
    50041 cgcgttgatc aaaggccaag gccgaaatga ttcccttacg actgaccttt tctaaataag
    50101 cttttttgtt tcttgttaat gtcatcttat acctcctcta cttgaatacg gtcaaatagc
    50161 tcatcaaaat gtgccatgtt aacatgacct gttcttgttt cttgcgcatt taacatgcct
    50221 aaaacattgg cttttttcag aagcgtctca tcgtcatctc cttctgccaa agcccaagca
    50281 atccctgcca cagtagcgtc accagatcca acaggattga ctacctcaat tttaggaatg
    50341 gtaacacggt aaaacctgtt atgatgtttg gcaaaggccc cttgggcacc aagagaaaca
    50401 ataatccatt ctatcccttc aaataaaggt tgactcaaca gagagattaa acgttcctca
    50461 tctaatgtga caggttggcc tatcaaatcc tccaattctt ccaaattggg tttgataaca
    50521 gttggtttat ctttgccagc cagtaccgct tttaaaggag caccagagca atctaaaacc
    50581 actttgctgc catagactct cgccatagta atcaagtctt gataatagtg agcggccaga
    50641 cccttaggca gactgcctga aaaggttaag acatcaaact gcttagcaat aatactcatg
    50701 tggttcaaaa agccttcggc ctcgtccata tcaatgtagg gaccagcttc cagaatttcc
    50761 gtctgcatgc cttcatgtaa aacagcaata caatttctcg tttccccttt gattttgaag
    50821 aattggttag aaatgccctg ttcttgtaac tgatgaatga caaagtcacc cagtttccca
    50881 ccaataaatc ctgttgccac aactgactga ccagcttctg ctaacactct ggtcacattc
    50941 agccccttac caccggctgt ttttgtcgtt ctgtcaacac gattaaccgt gtccaaagtc
    51001 agacgattta gaggatagga aatatcaatg gatgggttta aggttaccgt taaaatcatc
    51061 gcttctccct aatcgtggta gtcaccgcga tcccatttgt ccaaaaactc tgtaaagaag
    51121 tcaggatctt cttggttagc attatgactt tccaaatggg ctatcttagc aattaacttc
    51181 ttattctctt cggtttcctt atagtctgcc tttataaagg cctcaataat atcacacatc
    51241 aaaagctcac ctgtgatttt accaccaaag ccaatcacat tggcattcaa ttcttctttg
    51301 gcataaagcg ctgttgtcat atccctaaca agcgctgagc gaatgccagg aaccttgttg
    51361 acagcattag tgatcccaac accagtgcca cagatacaga caccaagatc agctaggcca
    51421 ttggcgacag cctcaccaac ccttttccca aaaatcgggt aatgggtgcg ggtatggtca
    51481 taggtcccac agtcaatcac ttcatagccc tttgatttca aaaaatctga aacagccatt
    51541 ttttcatcag tcacaatatg atcacagcca atagcaattt tcatgatatc ctcccttcgt
    51601 taagccattt tattgagcat gtcaacacga atttgatgac ggccaccatc atagtgacca
    51661 gtcacaaaac ctttagcaat attcttagcc aattcttgac ccacaatttc tgctcccatg
    51721 gtaatcatgc gggcattgtt atgaccgcga gtcatgtagg cagagcgttc atctgacact
    51781 tccgcagcga ccataccttt gattttggta gcgaccataa atggccctgc tccataagca
    51841 tcaatcataa tgcctagact ttcctcatca gccttgagcg ccctagcaac tgctagagta
    51901 ttgtcaacaa agtcatcagc aatcgccgtc acatctgtca catcaaagcc ttcctgctgc
    51961 aaaaagcctt taatagcctc ttttagatca tttccatgtg catctgcacc taagataata
    52021 gtcataggat ctccttttat tgtcattacc gttcaaaatt gtttattttt gttttgtttt
    52081 ttattatttt gttgtttatt gaaaaaagag actgtttatg ctattatgag ttaacaatac
    52141 accagagaaa gtagcggcct atgcttaagc gtgaaagatt gttaacaatt atggaaaagg
    52201 taaacgccaa cggctttatc actgtcactg atattatgga aagcctaagg gtttcagata
    52261 tgacagccag gcgaaattta gatgagctag caagggctgg aaaattagta cgtattcgtg
    52321 gcggtgccca gagcatttct atgcctcaaa agctggagcg ttcaaacact gaaaagctaa
    52381 ccgtacaaat tgaagctaaa aaagagattg ccagatacgc tagtcagctc attaatgatg
    52441 gtgagaccat ttttataggc cctgggacaa cactagaatg cttggctgag gctctaatca
    52501 accgtcacat ccgtattatt accaacagtc tgcctgtttt tacgattctt aataaaagta
    52561 aaactgttga tctcattctt atcggtggtg agtaccgagc catcacagga gcctttgttg
    52621 gcagccttgc aagccagacc atcttatcct tgaagtttgc caaggccttc atcagctgca
    52681 acggtattta taaaaatgac attgccacct acagtgaaaa cgaaggggtt attcagcgcc
    52741 tagcctgtga caatgccatc gaaaaatacc tgctcgctga caaccaaaag tttaacgcct
    52801 atgactttta cagcttttat caccttgaca atatcgacgc cattatcact gactccaaga
    52861 ttagtgacag cgttaaggag cgttaccgcc aatttgccaa gctcttaatc gcaaggccag
    52921 ctgacaatca ggtcagcagc tagacagcct gcctctctat ctgtttccac cctgagtcca
    52981 gcaggtaaac aaagctatca aacgaaatag catcataaaa gcgcatgaag ccactaatat
    53041 tgcaatgggg cttcatgcct tttttaacct atcacacgtt aagcaaagca aaaagaggct
    53101 aggacaaaaa tccttcctct tttaaaatcg tcaaactata gagttgattg gagggctctt
    53161 agccctcatt tttcaagcga tgtggccttt ttaatcagct gctcgagggt ggataaccta
    53221 atcaacatcg ccaggtcatg acgattgaat ggttattcca ctctttttct acgctgaggg
    53281 ctgtgaaagg gctcatacga cagcttagcc gctttctaac agctatttac ctacctcacc
    53341 tcttaacgag cagacagcct aaatggtata gtccagctga tcaagactct ttttatggtc
    53401 aaggtcaata tcaagaaagg tcatctgctt gatattgata aggctggcta caattgatac
    53461 cggaaaagca accaccgctt gattgaagag actaatatta ctattgacaa tgcgttttgc
    53521 tgctgccaag gctgcatttt ccttagcaat ctcattttgc aggctcaaaa actgctcaga
    53581 ggagcgcatt tccggataag cctctcctac agcaaaaacc tcattcaagg cctgctcctg
    53641 tgtcctcatc acatcatttg tttcctccaa ggaaagcccc tgacgcagct tcacgagttc
    53701 agtaaagacc ttttcctcat gcttggcata ggacttagcg atttttagca tttccgaaat
    53761 ggtatcatat ctcttctcaa gagcaatatc gacatttcgt ttagactcct ctataacgat
    53821 tcgatacctt tctaatttgt ttctcactcc aataagccat agtatagtca tgcaaagaat
    53881 aagtgttaac atagatgacg tcactgacat aaaaaagcct ccttaaagct gatgatttag
    53941 tgtatccaac aagcggtaca tcttaacaag cttgtcttga atgttttcat attcgctact
    54001 taacgatagc ttttcaatag cccctctaga gctaggggtt ttcaagagct gttgaccgga
    54061 atagaaggac acaacaacag tatcaccatt catataaact gctacaggca tctcctctct
    54121 ccattcatca agcactgcca gcatataagg atttaagagc attctagcgc ttaattcatc
    54181 tgtgcagtac acattgtacg tttcattaaa gcgaatgtcc tccatttcca gctgcacctc
    54241 accctttagc ttagccttgt agccactatg gaccttttct ctgcccaaaa agcccttttg
    54301 agtcggcaca attctaatat aacccttgat agctgtatga tatttagcca gcagcacctg
    54361 tccgttaaaa tcagtgaccc gatgccagtt atcatcctca ttttcctcat ggtaggcata
    54421 aagattgcaa aattctgtct gcatgtcatc tccaaaaata atatggcaat tactgtcata
    54481 ccatctggag gacggtgttg caagctttag taaggagagc tcaatccctg aatagtaatc
    54541 tatcttgaca tctggcaggg cctcttgtaa aacaggcagc aaaaagtgat ccacatagga
    54601 gagctcattt gctgttttga atgttttcag ccgcggccaa accaagcccc ccacaaagat
    54661 aatgagaaat aaggcaagag atcggtcaac catgccatac aagatgattg cgcctatcac
    54721 cattgccagc cagcccagat tattctttct agcatttcca ctcatctcgc ttttaatttg
    54781 ctccagcttt tggtgatgct caggcgaagc ttctatagct ctactcttct ccaaaacaat
    54841 aggatctgtc aatcgcttag tattttcgtt catctcactt actccagata cttctccatc
    54901 agcagcgctc agctgctctt gataacacca gtcactttat gcttttgctt aacctataaa
    54961 tgacaattgc gttacagcta atttataata ttataccatt tttaaactat tttttctatt
    55021 attatattta aatgacgctc aataataacc acataatgtt aatatagaca tcatcgtgct
    55081 cttttttacc taatcatgtt gtgagcaata cccccgttta tcagcggaaa ccataaaggc
    55141 ctctatgaga tcaagactat cagcgccagc ccttcttttg gagtcactat tcagcttgtt
    55201 cttcgcatgc tgtctttgcc tgaccatgat tcagctgctc tttttgattg cttgttatgc
    55261 tcactttttc cgtctcatgc tgagcaagaa aaaacagcaa acccttgctt ggtttactgc
    55321 tcttctgttg atgttagtca aaaaataagc cgggagctaa tgacacccta ttaactcata
    55381 aagcctgtta tcctttcttt gtcatagaac aattcactta gtctattctc aaccaaaata
    55441 cgaagcctgc ttaaaccgtc ttctcatatt aacagctaaa aagtggtgtc aatatgaaga
    55501 aacctatgat cggtaacaat aatagcacct ttaaatctct cagcgataat gtaaggttat
    55561 cctatacctg tcatattttt cggtgctatt tgccatatca ggttgctata gcacttggtg
    55621 gcttctggta gccttaacca ataaatgatc tgctttttta ttcctgctct ttgttttgtt
    55681 tatgcctttt gtcggcgcag gcctttagct ttactatact gacggtaagg tcggtgagag
    55741 cctttaccat tttttatgcc ttaatcgcaa agcatttaac accactgata ttgagctaag
    55801 gctcatcgca aagccagcca gcattgggct taatagaggg ccgccaaaga catgaaggat
    55861 acccatagca acggggatca ttaggctatt atagctaaac gcccaaaata aattttgctt
    55921 aaccactctg atggtttgac gactgagctc taggcattcc accacatcac gcactgctga
    55981 ggtcatcagg ataacatctg ccgcctcaat cgcaatatcc gtacctgagc ctattgagat
    56041 tccaatatcc gctagggtca aggccggtgc gtcgttgatt ccatcaccaa ccatagcaac
    56101 cagctgtccg ctagccttca aatccgcgat aatctgggcc ttttgagcag gcagcacctg
    56161 actaaagacc tgatcaattc ccacctcatt agcaatcgct tgagctgtga gggcattatc
    56221 tcctgttagc ataaccgttt gaagacctaa atcctgcaag gcccttatag ctgccttact
    56281 gtcagccttt agcctatcag caatcagcaa taaagcacat agctgattat ccttggcata
    56341 atacactacg gtttgcccct ttaaggcagc ttgctcggca taggtctgag cagcgcttat
    56401 cgcaatcccc tgctgtgaca tcagctcact attgccaaca gctaagcgat gctggtcaat
    56461 cacaccagtg acacccaagc ccacaagcga ttgaaaatca gtcacagcca gcaagtcata
    56521 gcccttttcc tgtgctactc taacaagcgc ttctccaaga gggtgctgcg aatactgctc
    56581 taaggaagcc acctcctgaa gtccctgctt ctcactagca gcaaggggga tgatccgctg
    56641 tagctgagcc tgaccctctg tcagcgttcc tgttttatca aaaacaattg tccgcacctg
    56701 ataagccttc tctaaaatat ctcctccctt aaaaaggatc ccctgctcag ctgcacgacc
    56761 tgagccaacc ataatcgcgg tgggagttgc tagacccaga gcacagggac aagcaataat
    56821 caaaacagct atagctattg tcagggcaaa atcaaagctc tctctcataa caaagagcca
    56881 aaaaagaaag ctcagcaggg ataaacttaa tacgataggg acaaagactc ctgataccct
    56941 atcagcaagt gcagcaatcg gagccttggc ttgctgtgct tgctccacca gctcaataat
    57001 ctgtgaaagc aaggtgtcat tgccaagcct agagggcttt acccttagcg ctccttggcc
    57061 attgattgtg ccagcaaaca cactatcacc tgtcacctta tcaactggta ggctttctcc
    57121 tgttagcatg gactcatcaa ccgtagactg cccctctact atcagcccat caacagccac
    57181 ccgttcaccc ggttgaataa agcaaatatc ctcattagtc acctgctcta agggaataag
    57241 ctgaagtgct ccctcacgaa taaccctgac atcagttacc cttaaggaca ttagcttctg
    57301 aatagcctgc gaggcccgtc ccttggtacg cccctccaaa tagctgccaa gggtaatcaa
    57361 ggtcagaata accacaacag attcaaaata aagctggtga gcaaattgag cagctccagc
    57421 tacaatctta aaacagctat atgagctgta aataaaagca aagctagtgg ctaaggtcac
    57481 aagcgaatcc atattaggcc gcttctttat caatgcctta aagccatttt catagtactg
    57541 ccgattcaag aaaagaacag gcagggtcag caaaagctga acaagaccat agcttatagc
    57601 atgcgactga ggtgctagag cgaccggcag caccaatcca agcataggtc ccattgcaag
    57661 gtatagcagc ggcagactaa agagagcaga ccacagaaag cgataccatt cattgctagc
    57721 ctgctcctct aggcgctcta gttgccctct catattggtc tcatcaagca gctctgctct
    57781 gtagcctgcc tttcttactg cttgaatgag ctctgctgag ctgaggctgt cagttgagta
    57841 gctcactgat agcttctcag tcgtcacatc aacagctgcc ccctcaacac ctggcagttg
    57901 cttaacagcc tgttcaatcg ctagagcaca ggaggtgcag tgcattccct ctaatagata
    57961 ggtctcttta acaatcatat cctctccttt ttctgacaat gacattgtcc tggcacacaa
    58021 tcacacctta catgggatac tgctccgact tttttagcct ctaagagcaa ctgaaaagcc
    58081 tgaatatctt ccagggtcat tggggtatcc tttagtaatg ccagcaacaa gcggctatgg
    58141 tggcgttgac acatgccatc aagcctctct cgtagcatag caagctgtcg cctgtcctga
    58201 tcaagcaagg actggtaaat ataggaccgt ccctgtctat cagcccttag ggcttttttc
    58261 ttaaccaagc gtccaatcaa ggtcttaacg gtagaatcag accaatggtg cttttcatga
    58321 agaatagcaa taatctcaga gctcttcatg ctcccattag cccaaacaac acgcataacc
    58381 tcccattctg catcagatat cgtatccata ttgctacctc tctttcatct acggttttat
    58441 taagtatagc ttatttgttt acgtttgtaa acaaataata actaaaaaag gtctctttat
    58501 gagaaacagc gtcaaaaaag gactgacagc taaagtcagc agctagcttt taatagtctg
    58561 aactttccag tcttatctga ttaactttat attgacaaaa tgagtccttg tatattacta
    58621 tatgacagta atactgtaat gattaaggag aaaacattga cgtatcttaa aagacagcta
    58681 attctactag cccttctact cacagctata ggtagccaaa caatcgttca ggccagcacg
    58741 cgatcctgga aaagctggtt tattgagcaa tatttttggc ttaaacgaga caaaagctat
    58801 tatgccgagc aggatgagaa taccttctac aactacgtca agtcagctgg tgaaaagagc
    58861 aatcaaggct ttaatctcac tcaaaatgag gtcaacggaa cattaaagac agagtataga
    58921 gacaacatgc aggttcacag ctggaatgaa aactctacta atccatcaaa tcaaaaggtc
    58981 attctctatc tgcatggtgg ctcctaccta aacaacccga cctcatacca tattgacatg
    59041 ctcaaaacct tgtcaactag ccttgatgct aagattgtat tgccgattta cccaaaggct
    59101 ccgacctata cctatgatgt cgctatgcca agattagtta gtctttatca ggatattcta
    59161 aaaagcacta ataacaatgc taacaatatc accatcatgg gagactcagc cggaggcggt
    59221 ctggcactag gtttggcact agcattgaaa aatgaagata ttaagcagcc taaggacatt
    59281 atcctgctct caccttggct tgatgtcacc ctatcaaatc cagagatccc aaattacgaa
    59341 gcctctgatc ctatcttatc ggcttgggga ctgcgcatag taggtgatat ctgggcacga
    59401 cgcggggaaa ataacactaa gcacccttat gttagcccta tctatggaga tacaagcaac
    59461 ctagcaccta tcaccatgtt tgtaggaact catgaaatct tctacccaga cattacaaaa
    59521 tttgatggta tgttaaaaca aaaaggacat aagcaccagc tatttgtcgg ggaaaagatg
    59581 aaccatgttt atcctattta cccgattgaa gaggccaaga cagcacaata ccaaatcatt
    59641 gataccataa aaaaagagta cgaaccccaa aaataataat acaaaaatgc ctaccagact
    59701 tgagtttttt gccaaagcct ggtaggcatt ttctgatcac agcatgacta ctgtttcttt
    59761 tctagctcac ggagcaattg atcaatttta ttaccatagg cgatagaatt gtccttttca
    59821 aaaaccaaat ccggaatttt atacatggtt aattgcttac caagctcacg cttaatggtt
    59881 cctgttgctt tttttaagcc tatttcagcc ttttgattgt ctgaagctag gtcactcata
    59941 atggtatagt aaaccttagc aactgacaaa tcgcccagca tttgcacttc tgtgatcgta
    60001 acaccctgca cacgtggatc acgaaccttt ttgtgtaaaa tctcgttgac ctcacgcttg
    60061 atttccatac caacacgatc aatacgatga tttgtcatgg cccttccttt ctattgtcaa
    60121 atagtacagg ctctcagtag ctcaataaca agagaaaagc ttgatgactt tcaagccttt
    60181 ttctctatta ggctgatggc tatactatta atagtgactg ttcaaatcaa gtggtgacat
    60241 tgtctattgt cttgagacga ggctatttaa gctactagcc accacgatta tttacgggta
    60301 atttcttcca tgacgtaagc ctcaatggta tcatcgacct taatgtcatt aaagccttca
    60361 atcatcaaac caccctcttg ggcattccca atctccttaa catcgtcctt ataatgctta
    60421 agactggcta gcttaccatc aaagataacc acgctatcac gaatgacacg tacacttgaa
    60481 tcacgcgtta ccttaccatt aacaaccata aagcctccga ttgtcccaac cttagagacc
    60541 ttaaaggttt cacgaataat agcctcacca agcatttttt cttgatactc agggtcaagc
    60601 ttacctttca tggcttcctc aacctcttcg atcaccttat aaataatgct atgcaagcga
    60661 atctcaacat cgtctgtatc agcctgctga cgcgcctgtg gtgttggacg cacattgaag
    60721 cctatgataa cagcgtttga agcctctgcc aaggtcacat ctgactcatt gatcgcaccg
    60781 acagcagagt gaacaacatt tactcgaacg ccctcaacat caattttaag gagtgaggct
    60841 gccaaagctt ccacagagcc ctgcacgtct gccttgatga tcacgttaac ggttttgatt
    60901 tcccctgcct tgagggtatc aaataggtta tcaaggctga cacgctgcgt gttttgacgt
    60961 tgcttgagaa gggcacgctt agcacgctcc tcccctgctg cacgcgctgc tttttcatca
    61021 gcatagaccg caaaatgatc acccgccata ggggtttcat tgagaccagt aatagatacc
    61081 ggtgtggacg gctcagctga tttcacacga cgaccaaggt catttgtcat ggcacgcaca
    61141 cgaccaaagg tgttaccaac aacgattggg tcttgtacgt gtagggttcc ttgttggacc
    61201 agaagtgtcg caaccgcacc cttacctttg tcaagtctag cctcaatgac cgtaccaatc
    61261 gcacgaaccg taggatcagc ctttagctct tcaacctcag ctaccaaaag cactgtttct
    61321 agcagctcat caatgttttt gttaaatttg gcagagattt caacaaactc acactcacca
    61381 ccccaagcag ttgagatgat cccatgctca gccaattctg aaataacacg ctcaggatta
    61441 gcccctggct tgtcaatctt gttgatggca acgataattg gaacaccagc cgccttagaa
    61501 tggttaatag cttcaatggt ttgtggcatt accccgtcat cagcagctac aatcaaaatg
    61561 gtaatatctg tcactgacgc tccacgtgca cgcatgcttg tgaaggcagc atgtcctggt
    61621 gtatccaaga aggtaatctt cttgcctgcc tcctcaatct ggtaagctcc aatatgctgg
    61681 gtgatccctc ctgcttctcc tgttgcaaca cgagaatttc taagggtatc aagcagggtc
    61741 gtcttaccat gatcgacgtg tcccataatg gtaacaaccg gtgcacgctc aacaatattc
    61801 tcaggattaa ggtagctatc atcagtaaag aagcgctcga tatcagcttc atcaacctcc
    61861 accttggcct tagcttcaat gccataatcc accattaaga gctcaatggt atcaccatct
    61921 aaggattggt tttgcgttgc catcacaccc atcataaata atttcttgac aatctcagcc
    61981 ggctcacgct tgatccgttt tgcaatttca gcaacggtca ttccttctga atattcaaat
    62041 tcttttggta attcatggaa tttacgctct gttactggtt ttggagctgt gttgctattc
    62101 ttatgatgct tacctttttt gtttttcttg ttgttattcc agttactatt cttttgattt
    62161 ctcacttggt tttgactatt ccaactcttc ttatttttct tttgtccatc ttctaggcca
    62221 tgatcccgat catgcccttt gtctggacga ttttgttttt tacgacgctt atcaaccggt
    62281 tttgctaccg atgcagcagc catactagca accgactcag tagccttagc tgaggcttca
    62341 cgatgctttt tgtcctctgt ctgagccttg agggcggctg ccttagcctc ttgccttgcc
    62401 tgttgctcta agcgtttagc ctcctcttgc tcacgaaagc gtgattccct ttgtctggca
    62461 tactctgcgt tttgctcagc ctttaaggca gcagcacgcg ccttaaaatc aatcttagga
    62521 gcaccggctt gggtctgccc ttgacgtcct gtatcctgtt gacgactatt agcgttaaag
    62581 gaacggtttt tgtcacgatt accagcttgt ctatgcccat cgtttcggtt atttccagat
    62641 gatggcctgt tatcaaagcg tctatctctt tgctgatttt gtgacttgtg gccagctcgc
    62701 tccgtctgct gaccttgtga tcgtccaagt tgacgatagt ctgacttgcg gtcattagag
    62761 cgattttgcc cagcctgccg tctcgctacc tgctccttgg cacgtgcttc acgctctgcc
    62821 ttgaaattgc ggctctttgg cttaacagca accggctgtg atgcttcttg tgtcgcagca
    62881 gctggctttt ctgctgcttt agaggctgct ggctgtggtg tagtggcctt agctgctttt
    62941 gctttttgtt ctgctacttg cttgtctttt gctgaacctg cttgaacatt cttagtcaca
    63001 cctgctgaaa agctagaggc aattttgtta gcatctgctt cttcgacgct tgacgcatgg
    63061 cttttgacat ctaatcctaa ggatttagca cgctcaacga cttctttact acttttgcca
    63121 atttccttgg caatttcatg taatcttttc tttgacaatt tgtgtcctcc tattcgtcta
    63181 tttcataaga gtcctcattt tctttgaaaa tccagcgtct gcaatggcaa ccaccttacg
    63241 aggcttgcca agtgcagcac ttaattccag tgcactaaac actgtggaga cttctacatt
    63301 gtaataatta cttttatctg ttactttttt agtgatattt gggccagcat cattggctaa
    63361 aaaaacaaga ttgacttcct gatgtcgaat ggctttaatg accaattcct cacctgaaat
    63421 cacttttttg gcccgctgag ccagtccgat caaatgagat aatctattta aactattcaa
    63481 ggcctagctc tcttctttta actttgtgat caacatgtgc aatcacttca tcgtaaaagc
    63541 tctctggcac ctccattgag aagctacgat taaacacctg ttttttcttt gccataagtg
    63601 cttcttggtt atctagcttg atataagcac cacgcccatt ttgcttgccg gttggatcaa
    63661 taaaaatctg cccctcctta tttttgacaa tacgaaggag gtcacgctta tcaatgatct
    63721 caccagaaac aagcgactta cgtaaaggta ttttttttac tttaggcata aaacacctct
    63781 tttcttacac ttcctcgttg gttaagagct cctctgtagc tactgcttca gtcattgctg
    63841 cttctttttc tgcttcaagg cgttcatatt cactggctga tttgatgtca atgcgatagc
    63901 ctgtcaaatg agctgccaaa cgaacgtttt gaccacgacg accaatagca agcgatagct
    63961 tattatcagg caccaccaca gtcgcacgct taagatcgtc atcatcaaag agaaccatat
    64021 caacctcagc aggtgcaatg gcattgtaga taaattcagc agggtcatct acccattgga
    64081 taacgtcaat attttcttct actgggatct caagtcctgt cttagcatca tagcgctttg
    64141 gatggaattt actgataacc tttttgatgt tgctgccgcc acgaccaaca atcgttccaa
    64201 tcgcatcaac attgggattg tggctacgca cagcaacctt agtacggtca ccagcctcac
    64261 gagaaacact cataatctca acggtcccat caaaaacctc tggaatttcc tgttccataa
    64321 tgcgcttgat gaactcaggg tgactacgac taacaaagac gttaaccccc tttggattgt
    64381 tttccacctt gtagacatag acatcaatcc gatcatgtga tttgaaggtt tctcctggga
    64441 tttgatcctg atgtgagagc tgagcctcta aggaaccaag gttaacataa atgaaacgtt
    64501 ggtcaaaacg ctcaaccgta cccgtcatga tttcaccttc atgctgcttg tactcattga
    64561 aggtgatttc tcgcatctga cgacgcatcc tttccataat ggtttgcttt gcagactgag
    64621 cagccacacg tccaaactcg ctgactgatt cttcaaaacg aatcttatct cctaactcat
    64681 aggctgagct aatggcaagg gcatcgttca ggctaatttc cagacggcta tcaaatacct
    64741 cttcaacaac ctcacgaacc gtaaaaacct gaaaatctgc tgttttatca ttaaattcaa
    64801 tgacgcagga ttctgcttga ccataacgac gtttataagc tgatttcagt gattcagtga
    64861 ctgcctcaat gatatctgcc ttatcaatgt gtttttcttc ttccaaaata cggaaggctt
    64921 ctagcatttc tttgctcata atgttgtcta ccttgctctc aaagcttggt aaaaatcctt
    64981 tcttatctta taaattaatc catttagggc ttagccaacc gactaaagca aatcgctcag
    65041 caattgcctt ataatttgac agctaaacga gccttagcca ctgcttggta aggaatctca
    65101 actgttttgt gacgcgtctt atctagataa tcaatggtta gggtatcacc atcaaaagcc
    65161 actaaatctc cttgaaaaac cttcacctta tcaattgccc gatagaggct gacattaata
    65221 tatgagccta cagcagcctt caagctctca gcagtcttta atggacgctc tagcccagga
    65281 ctggaaacct ccagcatata ctgatctggg aaagggtctg gagaaatcgt atctaagagt
    65341 ggactgatta actctgtaag ctcagcagta tcctcaacgg taatcccaga agccttatca
    65401 actaagatac taaggacata atcattgccc attttgtcgt attcgatgtc gaccaattca
    65461 tagggtgctt taattacagg ttctacgatt tgggtaacaa tatcaataat agctgtgttt
    65521 gcgatgttaa taacctcctt tactgatgac tgctatacct ctatagcctt gtcctcttga
    65581 taatcaacac aaaagtggcg agatatttct caccaccctt ctgtattgct ttaacctatt
    65641 ataccacaat caaaatgaat tgcaagaaaa tccctactaa aagtgtcaat aagacctcaa
    65701 aaatcctatt ttttaaaagg agaggagatc tttaaccttg cttttttctc tttccttatc
    65761 ccctctaacc tctgtattca tatgataaaa taaaatatta aagggtaaaa aagacaacta
    65821 aaatattatt tgcggctgct tcatggtctt taccaaaacg aaaaaacctc ccatcagaac
    65881 agatctatgc atatgcgaga gag
//
LOCUS       DARYLJ010000004        59764 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYLJ010000004 DARYLJ010000000
VERSION     DARYLJ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59764
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            84..1283
                     /locus_tag="TU746_000202"
                     /pseudo
     CDS             84..1283
                     /locus_tag="TU746_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            1377..1532
                     /locus_tag="TU746_000203"
     CDS             1377..1532
                     /locus_tag="TU746_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0890593.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(1714..2179)
                     /gene="tnpA"
                     /locus_tag="TU746_000204"
                     /pseudo
     CDS             complement(1714..2179)
                     /gene="tnpA"
                     /locus_tag="TU746_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(2466..2939)
                     /gene="tnpA"
                     /locus_tag="TU746_000205"
     CDS             complement(2466..2939)
                     /gene="tnpA"
                     /locus_tag="TU746_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL0890594.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            complement(3221..3586)
                     /gene="rplL"
                     /locus_tag="TU746_000206"
     CDS             complement(3221..3586)
                     /gene="rplL"
                     /locus_tag="TU746_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL0890595.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(3651..4151)
                     /locus_tag="TU746_000207"
     CDS             complement(3651..4151)
                     /locus_tag="TU746_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL0890596.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(4180..4315)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(4447..5088)
                     /locus_tag="TU746_000208"
     CDS             complement(4447..5088)
                     /locus_tag="TU746_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL0890597.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(5085..5852)
                     /locus_tag="TU746_000209"
     CDS             complement(5085..5852)
                     /locus_tag="TU746_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL0890598.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(5852..6604)
                     /locus_tag="TU746_000210"
     CDS             complement(5852..6604)
                     /locus_tag="TU746_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL0890599.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(6615..7745)
                     /locus_tag="TU746_000211"
     CDS             complement(6615..7745)
                     /locus_tag="TU746_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL0890600.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(7812..8498)
                     /locus_tag="TU746_000212"
     CDS             complement(7812..8498)
                     /locus_tag="TU746_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0890601.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(8532..9884)
                     /locus_tag="TU746_000213"
     CDS             complement(8532..9884)
                     /locus_tag="TU746_000213"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL0890602.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(9937..10893)
                     /locus_tag="TU746_000214"
     CDS             complement(9937..10893)
                     /locus_tag="TU746_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL0890603.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(10890..11741)
                     /locus_tag="TU746_000215"
     CDS             complement(10890..11741)
                     /locus_tag="TU746_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL0890604.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            11843..13186
                     /locus_tag="TU746_000216"
     CDS             11843..13186
                     /locus_tag="TU746_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL0890605.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            13186..13974
                     /locus_tag="TU746_000217"
     CDS             13186..13974
                     /locus_tag="TU746_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL0890606.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(14598..15587)
                     /locus_tag="TU746_000218"
     CDS             complement(14598..15587)
                     /locus_tag="TU746_000218"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL0890607.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(15829..17598)
                     /gene="lpdA"
                     /locus_tag="TU746_000219"
     CDS             complement(15829..17598)
                     /gene="lpdA"
                     /locus_tag="TU746_000219"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL0890608.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(17807..19216)
                     /locus_tag="TU746_000220"
     CDS             complement(17807..19216)
                     /locus_tag="TU746_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL0890609.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(19340..20338)
                     /locus_tag="TU746_000221"
     CDS             complement(19340..20338)
                     /locus_tag="TU746_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL0890610.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(20418..21386)
                     /locus_tag="TU746_000222"
     CDS             complement(20418..21386)
                     /locus_tag="TU746_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL0890611.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(21892..23802)
                     /locus_tag="TU746_000223"
     CDS             complement(21892..23802)
                     /locus_tag="TU746_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0890612.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(24212..24997)
                     /locus_tag="TU746_000224"
     CDS             complement(24212..24997)
                     /locus_tag="TU746_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL0890613.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(25103..26764)
                     /locus_tag="TU746_000225"
     CDS             complement(25103..26764)
                     /locus_tag="TU746_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL0890614.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(26974..27732)
                     /locus_tag="TU746_000226"
     CDS             complement(26974..27732)
                     /locus_tag="TU746_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890615.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(27729..28598)
                     /locus_tag="TU746_000227"
     CDS             complement(27729..28598)
                     /locus_tag="TU746_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890616.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(28612..29607)
                     /locus_tag="TU746_000228"
     CDS             complement(28612..29607)
                     /locus_tag="TU746_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0890617.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            29959..31629
                     /locus_tag="TU746_000229"
     CDS             29959..31629
                     /locus_tag="TU746_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL0890618.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(31718..32956)
                     /locus_tag="TU746_000230"
     CDS             complement(31718..32956)
                     /locus_tag="TU746_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL0890619.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(32946..34127)
                     /locus_tag="TU746_000231"
     CDS             complement(32946..34127)
                     /locus_tag="TU746_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL0890620.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(34190..34666)
                     /locus_tag="TU746_000232"
     CDS             complement(34190..34666)
                     /locus_tag="TU746_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL0890621.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(34844..35890)
                     /gene="rfbB"
                     /locus_tag="TU746_000233"
     CDS             complement(34844..35890)
                     /gene="rfbB"
                     /locus_tag="TU746_000233"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL0890622.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(36082..36678)
                     /locus_tag="TU746_000234"
     CDS             complement(36082..36678)
                     /locus_tag="TU746_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL0890623.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(36678..37547)
                     /gene="rfbA"
                     /locus_tag="TU746_000235"
     CDS             complement(36678..37547)
                     /gene="rfbA"
                     /locus_tag="TU746_000235"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL0890624.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(37604..38713)
                     /locus_tag="TU746_000236"
     CDS             complement(37604..38713)
                     /locus_tag="TU746_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL0890625.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(38768..39556)
                     /locus_tag="TU746_000237"
     CDS             complement(38768..39556)
                     /locus_tag="TU746_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL0890626.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(39546..40232)
                     /locus_tag="TU746_000238"
     CDS             complement(39546..40232)
                     /locus_tag="TU746_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL0890627.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(40306..40968)
                     /gene="nth"
                     /locus_tag="TU746_000239"
     CDS             complement(40306..40968)
                     /gene="nth"
                     /locus_tag="TU746_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL0890628.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(40968..41645)
                     /locus_tag="TU746_000240"
     CDS             complement(40968..41645)
                     /locus_tag="TU746_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL0890629.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(41712..42230)
                     /locus_tag="TU746_000241"
     CDS             complement(41712..42230)
                     /locus_tag="TU746_000241"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL0890630.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(42310..42678)
                     /locus_tag="TU746_000242"
     CDS             complement(42310..42678)
                     /locus_tag="TU746_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890631.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(42687..44897)
                     /gene="recJ"
                     /locus_tag="TU746_000243"
     CDS             complement(42687..44897)
                     /gene="recJ"
                     /locus_tag="TU746_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL0890632.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(44894..45658)
                     /locus_tag="TU746_000244"
     CDS             complement(44894..45658)
                     /locus_tag="TU746_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL0890633.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(45658..46587)
                     /locus_tag="TU746_000245"
     CDS             complement(45658..46587)
                     /locus_tag="TU746_000245"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL0890634.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(46602..47240)
                     /locus_tag="TU746_000246"
     CDS             complement(46602..47240)
                     /locus_tag="TU746_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL0890635.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(47233..48471)
                     /gene="hflX"
                     /locus_tag="TU746_000247"
     CDS             complement(47233..48471)
                     /gene="hflX"
                     /locus_tag="TU746_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL0890636.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(48556..49446)
                     /gene="miaA"
                     /locus_tag="TU746_000248"
     CDS             complement(48556..49446)
                     /gene="miaA"
                     /locus_tag="TU746_000248"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL0890637.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            49579..49755
                     /locus_tag="TU746_000249"
     CDS             49579..49755
                     /locus_tag="TU746_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL0890638.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(49911..50548)
                     /locus_tag="TU746_000250"
                     /pseudo
     CDS             complement(49911..50548)
                     /locus_tag="TU746_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(50705..52969)
                     /gene="glgP"
                     /locus_tag="TU746_000251"
     CDS             complement(50705..52969)
                     /gene="glgP"
                     /locus_tag="TU746_000251"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL0890639.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMDGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(52995..54497)
                     /gene="malQ"
                     /locus_tag="TU746_000252"
     CDS             complement(52995..54497)
                     /gene="malQ"
                     /locus_tag="TU746_000252"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL0890640.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(54704..55726)
                     /locus_tag="TU746_000253"
     CDS             complement(54704..55726)
                     /locus_tag="TU746_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0890641.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            55973..57226
                     /locus_tag="TU746_000254"
     CDS             55973..57226
                     /locus_tag="TU746_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0890642.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            57526..58887
                     /locus_tag="TU746_000255"
     CDS             57526..58887
                     /locus_tag="TU746_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0890643.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            58887..59723
                     /locus_tag="TU746_000256"
     CDS             58887..59723
                     /locus_tag="TU746_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0890644.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        17474 a        14025 c        11156 g        17109 t
ORIGIN      
        1 cattaacatt attcgtcata tttttacttt cattttcttt tcttggtcaa aaagaagtaa
       61 cggtatcgtc acgaggtgaa attatgccta caaaagtcat tgcatcaata cagtcaacta
      121 gcaacaatgc tatcgttaaa aataatctta aagaaaacca actcgttaaa aaaggaaaac
      181 gtttaatcaa atataaagaa accattgaga gttctcaaaa gaattctcta gaatcacaat
      241 taaatacgtt gaataaacaa aaagttggtt tagagacatt gaaagaaagt ctcaaacaag
      301 gaacgaacct cttaccacaa aatgatgaat ttggtcttgc tgacaccttc aacaacttta
      361 taaatcagtc tcaagagatt aaacttggta tcgctaaaat aaatacagaa gtatccaatc
      421 aatccacact tgcaaataac acccttgctg caattgatac tcaaatcaat actataaacc
      481 agcagatttc agaatatgaa gatcttcgtc aagctatctc aaatcataac acaatcttac
      541 caactggtaa tcctcatcaa gatattctca ataattatct gtctcaatca caagaagaat
      601 aaacttccac gtctaaccag tttatctctc agattaacca gactatttca ggtttagaat
      661 catccctctc tgggcttagc attcaaagag caggtactgg tagtagtgca acatacgata
      721 acagttcaga aaccaaagtt gaagtcttga ggactcaatt tctacagaat gcttcacaac
      781 agctgtcaac catcgacagt caaatcactg aacttaaagc tcagctagaa caagcaagtg
      841 tatagttaga cactaatgtt gttttagcac cagaaaccag gattattcat ctaaataatg
      901 aatacgaggg gaaaagtctt atcccaaatg gtagtgatat tgccaaaatc tatcctaata
      961 ttactcaaac tagaaaagct ctgattacat actttgtaac ttctgattat gtttctctcc
     1021 ttaaaaaagg tcaaactgtt cgtctaaatc ttcaaaaagt gagaaaacag tccatcactg
     1081 ttaatggaaa aatttctact attgataaaa cagcaacaaa aacagaacaa ggtaatcttt
     1141 tcaagattac aactcttgcc aaactccctt ccaaggatag ctacttgata aaatatggtg
     1201 cacagggtcg tgttacaagt gttatcgcta aaaaatccta cttcgacttt tataagaata
     1261 aactgttgtc aaatcatgat taaaccattc cggacgtttc gatgaccatt taggatttag
     1321 agaaataata tattgatctt aaattataat attagaaaaa agaaggaggt ccacaaatgg
     1381 aaaaacaaaa ttcactcact caatttcaag aactaaattc atccgaactc aatcaaataa
     1441 caggtggaga ttggtggtca gagatattaa attttaatcg ctctcaaaaa tataaacata
     1501 cctccgtggg ttctaataat attattgtct aacatatact tagtattgta ataatagttt
     1561 ttttagtaga aatcataacc acccgtccaa caggtggttt gaatagggac tataaaccca
     1621 tataactagc cagcgcctaa agacgctggc tttcactttg ttcaaaccac attgctattg
     1681 actcgtcact tgcctctcaa agaagtattt gtatcactta cccttatctc taaagggatc
     1741 ctcatattct tttacactca gtttatctag tgctatgtca tgtttttctt gttcttgaat
     1801 atattttttt attgtagctt catttaatcc aaccgtacta atataatagc cttctgccca
     1861 aaagtgtcga ttaccaaatt tgtatttcag attggcgtgc ttgtcgaaca tcataagcgt
     1921 actcttacct tttaaatatc ctataaaact tgaaacactt attctgggtg gaatgcttac
     1981 taacacgtgt acgtgatctg gcatcagatg tccttctata tatttctaca cctttatagc
     2041 tacataatct ttgaaaaatt tctcccaaac tgcctcgata ttgattatag attacttttc
     2101 gtctatactt aggggtgaac acaatgtgat atttacaatg ctactttgtg tgcgataaac
     2161 tgtggggctt ttgtgccata tttttactcc tttcgcttta caattggctt gaacacctat
     2221 attgtagcgc gtttggagtt tttttgtagt ataacgttcg atgcgtaccc gcatagcggg
     2281 ggatttttgt ttcgcaccta cggagcgaaa cggactaaag tcactaagtc ataaccacgc
     2341 gtaaaaacgg gtggcttgta caccggctat aagccgtttc tctccagcga cgtctaaaga
     2401 cgttcgctga acttcgttca ggttagtgct atgattactt gactaatgcc cgtaaaaacg
     2461 ggcttttatc ttgttttaaa actgccatct gaaaatggat cttcatattc tttaacactc
     2521 aacttatcaa gtgcaatgtc atttttctcc tgctcgcgaa tatatttcgc taccgtcctt
     2581 ttgttcagtc caacggtact aacatagtag cctctagccc aaaactttcg atttccatac
     2641 ttatatttta aattagcgtg tttatcaaat atcatgagag cacttttact tttcaaatac
     2701 cccatgaaat cggaaatcga aagttttgga ggtagcaaga cgagcatatg aacatgatct
     2761 ggcatcatat gtccctcaat gatttccacg cccttgtatt gacataggtg acggaaaata
     2821 tcaattaagt cctgtctaat tttgtagtaa atggattttc tgcggtactt tggtgtgaaa
     2881 actatgtgat atttgcacat ccatttggta tgtgataaac tgtaactggt tttagccatc
     2941 tctttttcct ccttgatcta acctgaacaa ttagattata acaggaaaaa gaaatggaag
     3001 ctcaaagcct tgtcagccac cagcatagct ggtggttttc ttgtttttct ctacgagaaa
     3061 aactggctcg aagccataat aaaaataaaa accctgccaa aaaatctttg gtagggtttt
     3121 tagcaggaaa ccaaatcaat ttatcagttt ctctaaatcg ctctaagcaa tcattaaacc
     3181 ttgatttact aggcttccgc aatcaaattg cgatactcta ttatttaaga gtgatagttg
     3241 ctccagcttc ttcaagctta gctttgattt cttctgcttc tgctgctgca acaccttctt
     3301 tgatgttagc aggtgcgccg tcaacaagac ctttagcttc tttaagtcca agacctgtga
     3361 tttcacgaac tgccttgata acaccaactt ttttgtcacc agcagatgtc aactcaacgt
     3421 caaatgaatc cttagtagct tcttcagcac caccagcagc agctacagct acaggagcag
     3481 ctgcagtcac accgaattct tcttcgatag cttttacaag atcgttaagc tcaaggattg
     3541 aagcttcttt aatttcagca ataatgtttt caatgtttaa tgccattgtc atttcctcca
     3601 aatagttata ttaaataatg atttgtagct ctaggctacc tctaaaggcc ttacgcagcg
     3661 ccttctttgc tttctgcaac agccttgaca gcgtatgcaa cgttgcggac tggagcttga
     3721 agtacagaaa gaagcataga aagcattcct tcgcggtttg gcaatgctgc aagtgcttga
     3781 atttcctctt ttgaagaaac aacaccttcg atagcaccac ctttaatctc aagtgcttca
     3841 gcagttttag caaagtcgtt gatgacttta gctggtgcga taacatcttc atttgaaaat
     3901 gctactgcag atggtcctac gaatatatct tttagctcgt caagacctgc tttttcagct
     3961 gcacgagtca agattgagtt tttgataacc ttgaactcaa cgccactttc acgaagtgaa
     4021 cgacgaagaa cagtatcttg atcaactgta agaccacgtg aatctacaac aacgatactt
     4081 acagctgctt tcattttctc agcgataagc tcaacttgtt cagctttttt agcgataatt
     4141 gcttcactca ttagttttac ctccgttttt atttttgggc taggcacaaa aaaatcgcac
     4201 ctaaacctag acacgaaagt acaaatacgt tatcttcaat aatgacgttt tgtgcctcgg
     4261 caggaatatt atgagcacgc tcccctgctg tcttaggtca gttttattca aaaccatagt
     4321 tagtatagcc tttttaaatg actttgtcaa cctatttttt agaaaatctt aaataaaaaa
     4381 ggaaagctct tggctttccg ctaaatagat ctgattagtg gctcaaaagc gcctcctaac
     4441 ttaagcctaa tgataagcaa cttgtgacga ttgattgcta taacttagcc cgatcaagct
     4501 ccacagtatc atctcataaa taaagaagaa caaggcaaag caatgcccaa aaaaggcctc
     4561 tggcaaaatc caaatgacag gatctgtcag cggatcaaac aaccagcttg aatctcctac
     4621 aaagagaatt tgatgaaaaa gggtaaagaa ctgatcaaag ccaatcatta aagcaaagca
     4681 agcaatcaca attggcaata aggctgctgc tattagccct cttcgaagca gcataaccct
     4741 tccttttttg atgctctgat aaaaatagat aatggttggc aacataagca ggctaaagat
     4801 cagctgtgtt atatgaaaca gcattttcac atctgtaaaa tgctttagac cagctcttga
     4861 tgctgaaaag ctggctagct ttagctcacg aacaaaagga ttggttaagt aagtcagcaa
     4921 tatattatag ttgtggagaa tagacttttt gcacatcaaa actgcctgct ctagttgcaa
     4981 ataatcaacc tcaatcggat aaagcagcca agataaatag atagttatca aaactgccag
     5041 tgctagtagc caaagccaac tggcaatgaa cttgcctttt tcaatcataa tagctcccac
     5101 tcatctaagc tagccaagac atgatcaggc ttaattggaa ggcttggaac ctcttttgcc
     5161 tttgtaaagc cggttgttac tagaatagtt gccatatcat tttgaattcc tgccatgata
     5221 tctgtcaggt aattgtctcc aaccatagcc acctcagaac gtggtacctt taagatctct
     5281 agggctttat tcatgataat cgcatttggc tttcctataa atactggctt cactctagtt
     5341 gctgcctcaa ggagcgcatt taaagcgcca gcacctggca ttagcccacg ctctgttgga
     5401 atatttaagt caggattggt cccaataaac aaggctcctt tttgaatggc aagtgttgca
     5461 attgataaca tttcataggt aacctcagta tctaagccaa caacaacata ggctggattt
     5521 tctgtatcct cggtatagcc tgcctctgca atggcagact ttaagccagt ctcgccaatc
     5581 acataggctg ttttgcctcg attcatatca ttcatgtaat caacggttgc cattgtagcg
     5641 gtgtaaatgg tttcaagacc tgtatgaacg ttaaattgat tggctagcat ttcctgaacc
     5701 atttcaggtg ttcttgtggt gttgttggta actaagagat aagggatacc tttttcctgt
     5761 aaacgcttga taaagcgctc accagccggg atacgatttt tcccttgata gatggttcca
     5821 tctaaatcaa ttaaataagc tttatagggc actaatttgt ctcactttct ttagtcgtta
     5881 taggctgcca tttgataatg gcctgcgcat taagctggcc tgatgacctg atctcatggt
     5941 aggaggtcaa atgctctaga tgatagcctg aggttatttg agtgctgggc ctcacctctt
     6001 tgatataggt caaggtaagg tggcaaggtc tgtggtgtaa taaaaattca tatcccaaaa
     6061 cgtcatacat ccaatccaaa tacttactat tattggcatg accattcata tcaatgtcaa
     6121 aataacgaac ctgataagct tgaaccatag gatcctgaag ctcatctatt ttgataggac
     6181 gcttgatttt cttaacaaag tcagcctgat aaggcaccac caaatcatct ggtatcgcag
     6241 ctgccttacg tgtttgagga tttagcaggg caaaatgaga taaaatggtc atgatggcat
     6301 gacctgcctg atcataaatg tgaaattgcc ggtaacaaaa taatttattg taagaaatag
     6361 cttgcgtttc aatggttact gtttccccaa accttggcat acgatcaatc gttacatcat
     6421 aatccgtaac aacccaaatc aagccatatt gctgaagtaa cacctcattg cctcgtccaa
     6481 tttcagctga ttgtcttgct gataccatta agcaatgtgc taataaaagg ggcagcttga
     6541 catcagcctt aacatcacaa aaatcaaaag acagcttaag gctttcgcta taccttaatc
     6601 ccataacaca cctcctaatc taagatgaat ttttcagcga cagaatcacc taaaaagagg
     6661 ccttttttgg tcattctgat aaagtccttg tcctctacca aaagcccctg attctgaagc
     6721 tctctcacaa caggaccata gcgtgactca aatgataggc caaatttttc ttgaaaccga
     6781 ctgactgata ctcctgattt ttttcgcaga ccaagaaaaa gctcctcctc catcatctcc
     6841 tccttggtga gcacttcctc acttaaccta gcatttccat ctgctactgc ctttaggtaa
     6901 tgctgaatag gaacccggtt gcggtaacga atcccatcaa gatagccaga agcccctgcg
     6961 ccacagccaa aatactcatc attattccaa tacatcagat tgtgcctgct ttcaaagcca
     7021 ggcttagtaa aattagaaat ttcgtaatgc tcaaagccac tggcttccat ttcagaaata
     7081 atatactcaa acatctcagc ttccaaatcc tcagtgggca aatggagctt gccacgacgc
     7141 attttgttca taaaaacagt gtgatgctct aggataaggc tatacaggct aaggtgagga
     7201 atatctaaag caagtgcctt agccacattt tccttgacct gctgcatggt ctgtccaggc
     7261 aaagcataaa tgagatcgat agacatattt tgaaagcctg cctccttaag actagcaatg
     7321 gtcgtataaa tctgagcctc agtatgactg cgtccaatct gctttaattg cttgtcatta
     7381 aaagtttgaa cgcctaggga aatccgattg acagccgatt gccttaatac tgcaatctta
     7441 tcctcagtca aatcacctgg attggcctcg atggtaaatt cttcaagctg gtctagctgt
     7501 aggtgctgct gcaaatggct cagcaaataa tcaagctgat tggctgttat ggctgttggt
     7561 gttccaccgc caatataaag tgtcttcaag gagctgatct gataggattc aaattcctta
     7621 atcagtgcct ctaggtaggc atcgacaggc tgatttttga taaatacctt agaaaaatca
     7681 caatagtagc aaatttgtgt gcaaaaagga atatgcacat aggctgaggt tggttttttt
     7741 gacatggtaa tattatatca ttttagctca gaaattcatg ccaagtgatt agctttttga
     7801 catgtactaa cctaaggctg cttctttttc tccattctca caaaggaatg actactccca
     7861 ttagcatact gctcaaagct tgaggttggc tgatagccca ttttttggta gaggctttgt
     7921 gcgcctttat taaagctagc gacatttaaa acataggttt cttgcggata agtagtgcta
     7981 gcaaaggctt caatgctgcc caaaaaagaa acaccatctt cctgaccagt agtatcaggg
     8041 gccataccaa gaccaatctc aagctctgat tcctgttcaa aaaagctggc aaagccaaaa
     8101 agaacaccat tgcgaagcac ttgaaagtaa tgctctccac gcgccttggg tgacaatatt
     8161 gactgatagt cctcaggatc agcagtcatg ctatagcact cataagctgg gctatagatc
     8221 cagtcatgcg caatgatttc agcactatgc tgtgtcatcg gcatcaggta aaaagaagac
     8281 tcagacaata agcgatgaaa ggtcttgttg atatgcttta tgcgacgccg ctgcacatca
     8341 ggctgatctg tttgataaat gtaattagca tagccctcct gatattctgg aatcattgtc
     8401 aaatacagct tttgggtcaa ctcatcaagc tgactagcaa tcctatccac tctatgcttt
     8461 atcatattac ctccaattct aatgctgctt gatagcataa aaagtgccga agcaacgaca
     8521 ctttttctag attaatcaag gccaatttcc gcacgaacaa ccgctgcaat ggtatcaaca
     8581 taatagtcaa cttcttcatt gcttggtgcc tctgccatca cacgcaacaa tggctctgtg
     8641 ccgctaggcc ttaccaaaat gcgaccatta ccagccattt ctccttccat ctgagcaata
     8701 acctcagcaa tagcaggcac ttccatagca cgctccttca tgctgttgtc aacacgaata
     8761 ttaacaagct tttgtgggta aatagtgacc tcactggcca attcggagag agttttacct
     8821 gtctccttca tgattttggt gagctgaaca gctgtcagtt gaccatcacc agttgtattg
     8881 taatccatga taatgacatg ccctgattgc tcaccaccaa gattgtagcc gaactgacgc
     8941 atctcctcaa caacgtaacg atcaccaaca gctgttacct tcttatgaat gccacagcta
     9001 tctaatgcct tgtgaaaacc aaggttagac atcactgttg tcacaatcgt atttttagct
     9061 agcaagccct tctcagaaag atacttgcct atgataaaca tgatcttgtc gccatcaaca
     9121 atagcaccat tttcatcaac agcaattaaa cgatcactat cgccatcaaa agccaatcca
     9181 atatcagagg ctgtttctgt caccaagtcc tgaagctttt cagggtgtgt agagccgata
     9241 ccatcattaa tgtttaatcc atttggattc tcaccaataa ctgtaatgtc tgcatttaaa
     9301 tctaaaaaga cattacgagc tgaaacagaa gctgcaccgt tagcagtatc aagagctatc
     9361 tttaaaccgt ctaaatctgc tccagtagta accaagaatc tctcgtactt gcgcaagcct
     9421 tctggataat caaccaaggc tcctaagccc tccgcacttg gacgtggtag gaggtcctct
     9481 ttggcatcta agagcgcttc gatttctagc tcttgctcat cagccaattt aaagccatca
     9541 ctcccaaaaa acttaatgcc attgtcaaga gcaggattgt gactagctga aatcatgaca
     9601 ccagcactag ccttttctgt acggaccaaa taggacacac caggagttgc aagaacacca
     9661 agcttataga cctctatccc aacagaaagc aagccagcaa tcagggctgc ctctagcatt
     9721 tcaccagaga tacgggtgtc acgagcgaca aaaactctag gcctttcagt ctcatgctga
     9781 cttagcacat aaccaccgaa ccgaccaagc ttaaaagcaa gctctggggt caactctaca
     9841 ttagcctcgc ctcgaacacc atccgttcca aaatattttc ccataattta tatcagctaa
     9901 acgcttcctc cattccattt tcctagctat tatgctttat tttttaattg ttgtcaactg
     9961 aacggttact accgaaggct ctatagaaac ctgatttgaa accaagctga ccgttttgct
    10021 cgtgtttttg gtgacgtcag aaatattgac ctctgccacc acctcatcaa tagtttcaag
    10081 gacctcccga ctaccagaaa taacagcggt ctgcttggag agcttatact ggatatctga
    10141 cagactgtca tccattagtc caactgcctc gactcgaata ggaactgatt tggtgatttt
    10201 tttgacagaa actgacaaat tagccttggc tggatcgatc gcactagcta aaatggtacc
    10261 atcggcagct actgcctgca gggttactcg gctgctataa ttagcatcta gcacctgatc
    10321 atcaggtaat ttagcgacaa catgatctat caaggcaata gtagactcat cacttgtgac
    10381 ctcaaccttg tcaatacctg tttcaatttt gctaatctca tagcccttag ccagctgctt
    10441 actatcgacg ctgccacgca ccggaaaggt ctttgttttc ttatttccaa tcgttaccga
    10501 aatcttatca ggagaaacag ttgctgtcac accagtaggt agattgataa cctttagggt
    10561 caccgttgca gtacctggct tactctttgt tagatcagct acgatcttaa agcttctagt
    10621 gtcactgttt acctctgaat ccagctttat gcggttggta gaggtcagat aaacctctgc
    10681 accgtaagaa tagccgctga tgaagtactg atcactatca tacttgatat caataggaac
    10741 gtcctttaag ctatgggtgt aggtttcaat agggctataa atttgagaat tagaatgatt
    10801 atgactgcta gaagcagcgg tcaaaaaaag aataatcgca aaaaagattg acactaagcc
    10861 cagcccaaga cgactattta aaaacctctt catttagctt tgcctcctaa gattttttta
    10921 taccaaggta atgtcgcacc gggctcattc atcaaatgag tcttgagaac cgcctcaagc
    10981 tcttctgttg aaaggtcgtg taaaaattga cccttacgag cgatagagac agctcctgtc
    11041 tcctcagaaa caattatcgt tacagcatca gaattttctg aaagtccaat tgctgctctg
    11101 tgacgtgttc caaattcttt ggaaatcgac attgattcag acaaggggag ataagcacag
    11161 gctgcagcaa ttttattgtt agccacaatg accgcaccat catgcagcgg tgtgtttggg
    11221 ataaagatat tgatcaatag ctgactagaa atatcagcat ttaggggaat tcctgttgcg
    11281 atatattcct gcaaggtctg cgtttgctca atagcaatca gagcaccaat cttccgcggt
    11341 cccatataag caactgattt taagagcgca tcaaccagca tctcctcatc actcaagctt
    11401 tgcttttgca aaaatacctg tgttgatcgg ccaaattttt caagccccgc tcgaatttcc
    11461 ggagcaaaaa tcaccacacc tgcaatcact ccataggtga tgacctgatt catcagatag
    11521 gttatagtcg taaaccctat ccactcggca atcacacgaa tgatgataaa gaatataacc
    11581 ccttgtacca aggacatgat cttagttcct gccaaggatt taataaaacg gtaaatcaaa
    11641 taggctacta ttaaaatatc cagcaaatga accaccaaca tcaaggggtc atcaatcagg
    11701 cttagtaaaa attttgtgtc aatacttgat aaattactca tacaattctc atttctatgt
    11761 cagatagata cctctaacat tatatcacgt ttcaagatgt tttccctatc taaaatttaa
    11821 gaacttatgt taaaatatta acatgaaact aaagacacta ctcgctatag cagccggaag
    11881 gactgcgcag ctcattttaa ataaaatcgg aagaggctca acctaccccg gacgattggc
    11941 cttgatgtgg gataaggata ttttagacac acttgccaag gactatgaga ttgttgttgt
    12001 gacagggaca aatgggaaaa ccttaaccac agctctaact gttggtatcc taaaagaagc
    12061 ctttggtgag gttttgacta atccaagtgg cgccaacatg atgacaggga ttacctctgc
    12121 ctttttatct gctaaaagaa aaaaaacagg caagcctatt gccgtcttag agattgatga
    12181 ggcaagcctt gcaagggtaa caacatacat taagccaagt ctttttgttt acactaatat
    12241 ctttcgagac cagatggatc gctacggtga gatttacacc acctatcaga tgattgttga
    12301 tggtgctagt caagcgccga aggcaaccat tctagctaac ggtgatagcc ctatctttgc
    12361 ctcaaaggac ctggttaatc ctgttaaata ttatggcttt gacacaccta agcatgagcc
    12421 acgcctagct cactacaaca ctgaaggcat tttgtgccca aaatgtgaac agattctccg
    12481 ttatcgtctc aacacctatg ctaatctagg agactatacc tgcttaaatt gtgatttcca
    12541 aaggcctaag ttggattaca agctaacgca attaaccagc attacccatc atagctcagc
    12601 ctttgtgatt gacgatcaga cttatcgcat aaatgttgga ggactctata acatctataa
    12661 tgccctcgca gctgttgctg ttgctgagtt ttttggcatt tctgctgatc agattaaggc
    12721 tggcttcaat aaaagcaagg ctgtttttgg tcgtcaggaa accttctcca tcaacggtaa
    12781 agcctgtacg ctggttctca ttaaaaaccc tgtgggtgct agtcaggcac tagaaatgct
    12841 gcgcctagcc gattatccct ttagcctatc tgtgctttta aatgctgatt atgctgacgg
    12901 tattgacaca agctggattt gggatgctga ttttgaattg attaatcaaa tggacattac
    12961 tgagatcaac gccggtgggg ttcggcattc tgaaattgca agacgcttac gagtgacagg
    13021 ctttgatgag gctaaaatca catcattcga taagcttgaa ggtatcatgc aagccattga
    13081 aaaccaagag gctgagcatg cctatatcct agcgacctat actgctatgc tagcatttcg
    13141 tgagctgctt gccagccgcc acattgtcga aaaggagatg atctaatgac ctatacctcg
    13201 ctacaatctc cggaaaatcg cgattatcaa tacgaccttc atattgctca cctttatggt
    13261 aatttgatga atacctatgg cgataacggc aatgtcttga tgttgaagta tgtcgctgaa
    13321 aagctaggcg ctaaggttag agttgatatt gtatccattg gggatacctt tgaccaagat
    13381 gattatgaca ttgttttctt tggtggtggt caagattatg agcaagccat tgttgctaga
    13441 gatttgccat caaaaaaaga ggccttagca gcctatattc accaaaataa ggtactcctt
    13501 gccatttgtg gtggctttca gctgctggga cagtactata ttcaagccaa tggccttaaa
    13561 atcaatggca ttggggttat gggacattat accttaaacc aagataataa ccgctttatc
    13621 ggaggcatta aaattcacaa tgatgacttt gacgaaacct actatggctt tgaaaatcat
    13681 caaggacgga cctttttatc tgacgatgaa aagcctcttg gacgtgtcat ttatggaaat
    13741 ggtaataata aagaggacca aactgagggc gtccactata aaaacgttta cggcagctac
    13801 tttcatggac caatcctttc gcgtaatgtc agcctggcct atcgcctagt cacaactgct
    13861 ctcaaagaaa aatatggctc gactgtttcc ttagcggcct atgataagat cttacagcat
    13921 gagacctcag aggaatacgc tgatgttaaa agcaaggcta gctttgacag ttaagtcctt
    13981 ctcatagcct gattaaacca caacagacat gcaaaacagt tattcccgaa tgaaaatata
    14041 gatttaaata gacaccctca atgtttttcc tatcataaaa tccataaaag ataagacata
    14101 ttcttgcaat aactgaacat tgaaagacag aaagctttct gtccttacta aacatctttc
    14161 atgcgtctgt cgtgctgatc aagcgagata accccaaaaa agtgctagca cagtaacaaa
    14221 atggctatga ccatatgtct gtgcagctct actgtcactg catagacagg ctagagggga
    14281 cgccctactt ggttcagcga tctaggggta ggtctagctt gtttgtgctg agtctgtttc
    14341 ggtagcaaag attgaatcct gctataagat actctcaaaa agattaaccc aaaagccttg
    14401 caacacattt aacgttttta gggataagta ccgatatgca gacacatagc aggagatcta
    14461 tgtgtctggt accaaaggac acaaaaaact aaagtaacac actaaaagcc acatgatacc
    14521 catttgatag ggggcgtcat gtggcttttt tctatctcac tgttcattac aaaaagccaa
    14581 accagcttct ttttgcatta ggcaacaatg gcctttgcca cctcttctac tgtcatacgt
    14641 gagaaatatt gtgttgtatc aatggtttga agacgctcaa gcacatcagc atactcgtat
    14701 ttgcaaccaa tgagtaggct ttcaatatcc tgcacgtcct taataccaaa gaaatcaccg
    14761 tagatcttaa gattcttaat aacagaattt tcaacattag caaaggttga gattttaccg
    14821 gcagggtagc gaacattacg ttcaatcgtg tattcaggtg cctttccata ggtccaatcc
    14881 cagctcccaa attgctcctc agccgattgt tgaatcttag ccagctcgtc ctctgacaag
    14941 acgtattctg tcatgtctgg ataggtctcc ttcattttaa ccaaaatctt gtctgaaaat
    15001 gcttctacgc tgattttttc tggcagctca tttaaaatat tggtcacgcg ggctcgtaca
    15061 gatttgactc ctttggactc aatcttatcc ttactgacct tgagcgcatc accaagaaca
    15121 gtcatatcca catcaaacaa gagacagcca tgatgcatca tacgtccctt ataataggct
    15181 tgagcattgc cacagatttt cttgccatca atttcaatgt cattgcgacc tgtaaaatta
    15241 gccttaactc ctaaatcagc caaggtctca ataactggct gtgagaaggt tttaaaatca
    15301 aaggctcctt ctgttgtttt attggaaata atcgtgtagt taaggttatt gagatcatgg
    15361 taaactgcac caccgccaga caagcgacga accacatgaa taccatgctg ttcgatgtac
    15421 tccttgttga tttcctgaat ggtattttga tgcttaccaa taataatagc cggctcattg
    15481 atccagagga taaacaattc atcctcatca accaattctc taaaggcata agcctctaga
    15541 gcaatgttaa aggcagggtt gtggctctta ttaacaatgt atttcatttc tatctcctat
    15601 agcgataatc gttatcatat tctattcttt attctaatgg aaactcttac aaaagacaag
    15661 ctaaaagagg ctagcaaaag caagggaact agtaaatgct tcctcaatca agaaccatct
    15721 gcaagctagc agtaaagctt gatctaactt aaagagcctt ccttgtatca acgaaagagc
    15781 tgagaaatct ttttcccagc ccttttttat cgcagctata tagctagctt attttttacg
    15841 ttttggtggg ttatgaatgg cttcgccaag cacatctgca aaggcttcgt acatcacctc
    15901 tgagaaggtt gggtgtccat gaattgacaa tagcaattca tcaactgtta gctcagcctc
    15961 catgattgtg gctgcttcat tgatcatttc agcggctgct ggaccaatga tgtgaacacc
    16021 aagtatttca tggtatttag catctgcaat aacctttaca aagccatgag cctcgtttga
    16081 cgcaatagca cgaccatttc ctgtaaagct atttttacca ataagaacat cgccatattg
    16141 ctcacgagcc tgctcttcag ttaaaccaac catagcgacc tcagggtgag tatagaccgc
    16201 cgctggagtg tattttaggt tagccttacg tgttgtgctg ccatgcatgg cattctcagc
    16261 agccacctca cccatacggt aagcagcgtg ggcaagcatt ttagtgccgt taacatcacc
    16321 cggtgcataa atgcctggga ttgacgtttc ttggtagtca ttaaccttaa tgcggttacg
    16381 gtccatttca aggttgaggt tttcaagacc attcatctgt ggcacacgtc caatagatag
    16441 caaggccttt tcagcaacaa cctcttcgcc attattaagc ttcaaggtca actggttgtt
    16501 ggcttcaaca atctcagaga caccaactga ggtctttatt gtcatgcctt tcttagaaag
    16561 gattttttga agctccagtg aaacctcctt gtccatggca ggaataatgc ggtcagccat
    16621 ttcaataact gtaacctcta caccgtaaga ggcccaaaca agaccaagct caataccaac
    16681 aacaccaccg cccataacag caagtgattt cggcatttca cgcaaatcaa gaatatcatc
    16741 agatgtcaag acaagcttag aatcaatccc tggaatattg atgcgtgaga ccttagagcc
    16801 tgtcgcaaga ataatattgc gccctttaat ggtttgcaca ccaatggtaa ccgttttatc
    16861 aggatttacc tgaccaaggc cattaaagat ggttaccttg ttggctttaa gaagcccttg
    16921 aaccccacct gttagcgtct taacaaccgt atttttaaag tcaactgtct tatccatgtc
    16981 aatagtatag ttggttgaag caaggttaat cccgcgtcct gctgcaatct tgatgccatc
    17041 aaggatttca gcatttttga ggtaggtttt tgttgggata cagccaacgt ttaagcaggt
    17101 accgccaaat tcagattttt caacgatagc aatcttgccg cccagctgag caccacgaat
    17161 agcagcgtag taacccgcag gaccgccacc gacaacaatg atgtcatatt catcagcagc
    17221 aagctctgcc tttggtgctg atggcgctga tccttgatcc ggtgcctttg gcacctcaag
    17281 accagccgcc tgtaaatcct cggttgtacg cgcaacattg acatcagccg ctgctgggct
    17341 tgatacatcg atagcttcac ccgcagctcc aatgtagccg ataacttcgg ttacagggac
    17401 tgtctcacct gcctggcgaa tgatttttaa aagcacacct gagtcttctg cttctaattc
    17461 catattggtc ttgtctgaca tgatttccag aagaatgtca ccctcgctga cagtgtcacc
    17521 ctcctgcttt ttccactcga tgatctcgcc ttcttgcatg tcaacaccga gctttggcat
    17581 aataatttca acagccataa tgatattgta aggaacgttc aaatgcaatc agatgcctta
    17641 acaatcagca ctggctaaca taagcctgct aaaagccctg catttagctc atagctagtg
    17701 actacgagct cgttccagat cctttctata gttttaaaga attatctttt cgttactttg
    17761 tttctgaaat atgctctctt tgcatcgcag gccataaggc ctgtcatcag attagcagtt
    17821 caaatggatt ttccatcaat tttttgagat caaccatgaa tttagcacca ttcatgccgt
    17881 ccaccagacg gtggtcaatt gtcagacaca ttgccatgat tggacgtgca acaatctcac
    17941 catcgaccac tgttggggtt ggaatggttg ccccaatacc tagaatagct gaattaggct
    18001 gattgataat tggattgaag gttttggtgc caaacatacc cagatttgtg atggagaagg
    18061 ttgagcctga catttcggta gcctttagct tgcctccttg agcctttttg ataacgtcct
    18121 tagaagcaag gacaaactct gagagactca tcttatctgc accatgaaca actggcacaa
    18181 ctagcccatc atcaagtcct acagcaatac caaggttgac aaagcgatga agctcaatat
    18241 cattagcatc attaatcaat gacgcattca tgtattcgtg ctctggcttc atcaaggtct
    18301 taacaacggc taaaccaatc aagtcagtaa agctaacctt tagccctgtt ttagccatga
    18361 ttgggtcaat cagcttcttg cgcaaggcaa tcatttcggt catgtcaatg tcataattaa
    18421 gcgtaaaggt tggtgctgta aggtaggaat gtgtcatacc ctttgaaata gccttacgca
    18481 tagcagacat cttcttaatt tcaacaccct ctggaagctc cttagcaggc ttttcttcag
    18541 caatagatgc tttttccaca gcaggtgctg ctgcgccaag cacagccaaa atgtcctcct
    18601 tggtaatctt gccaccaata cctgttccga ccaccgctgc aaggtcaact cccttgtcgg
    18661 cagctatctt acgagcaagt ggcgttgcct taggctgagc tcctttgaag ccttcaacgt
    18721 cttctttgtg gatacggccc tttggtcctg ttcctggcac ttggttaagc tcaattccca
    18781 tttctgaagc tgctttacga gctgctggcg ttgcgcgtac cttttctccg aaggctggag
    18841 cattggcaac tgatgctacc tgaggcgctg ttgaggctgc ttctttcggt acagttgttg
    18901 tattagcttc tgctgatgtt ggtactggaa tttcagttgt tttctcactt gaagcagtac
    18961 tattatcaac agattcacct gcagcaccaa tatagccgat aacctcagtg acagggactg
    19021 tttcacctgc ctggcgagtg atttttagaa gcacacctga atcctctgct tcaagctcca
    19081 tatttgtctt gtctgacatg atttcaagaa gaatgtcacc ctcgctaaca gtgtcaccct
    19141 cctgcttttt ccactcgatg atctcgcctt cttgcatgtc aacaccgagc tttggcataa
    19201 taatttcgac agccatatat ttcctttcat ttaatcccgc agcccatgat cttaagacca
    19261 gatacagctg ctgaaaaaag ggatactgtt ttatcagcct gatgaagaaa gcctctaagc
    19321 taagacttcc tttgccatgc taatttccct tgttgaccat ttttacaata gcagccttga
    19381 ttttagcaac atctggtaag atagcttgct caagaacacg tgcataaggt actggtacgt
    19441 cctcactagc aagacgcaca attgggtgat caaggtaatc aaaggcttca ctttcagtga
    19501 ccattgctgc aatctcaccg ataaagccac cagtcttata ggcatcatta acaagcataa
    19561 gcttccctgt cttcttaaca gaattaataa ttaattcctt atctagtggg ataagggtac
    19621 gtggatcaac aacctccaca ttaataccat cagctgcaag ctcttcggct gcctgaagga
    19681 cacgctctag catacgccca taggaaacaa tggttacatc agtcccttca cgcttgatat
    19741 cccccttgcc aagtgggata taaaaatctg gatcctgatt gacctcttct tttttaccgt
    19801 acaaggcctt aggctccatg aaaataacaa tattgttatc acgaatagct gactttaaaa
    19861 gtccctttgc ttcgttagca gttccaggtg caaccacctt gatcccagga atatgcgtca
    19921 accaagcctc aagagattgc gaatgctgag ctgcagatcc aattcctgag ccagaagcaa
    19981 cacgaaaagt tgctggcgtg atcaagccac caccaaacat gtagttgttt tttgccccat
    20041 tattaacaat tgcatcaagt gcaatggtaa taaagtccat aaaagtaagg tcaacaatcg
    20101 gacgaagccc tgtaattgct gaaccaatcg ctgcacctgc aatagcagcc tctgaaatcg
    20161 gcgtatcctt gacacgtttg gcaccaaatt cctcaatcat gccaacagaa gtaccaaagt
    20221 ctcctccgta aacacctacg tcctcaccca taaggtaaat cgtgtcatct ttgcgcatct
    20281 cctctgtcat ggcaagattg atagcctcac gcaaagccat taattttgtt tctgtcatta
    20341 ttatctccta atgtttacaa aatagaattg tcaatgttac tgtgaataga tttttgctcg
    20401 atgtgctagc agatcagcta gtctacccaa acgtcctcaa aggctacaga aatgtctgga
    20461 tctggactat tttgtgcaaa ctcataagcg tcatcaattt cttgcttgac ctgtgcttga
    20521 agcgcatcta attcttcatc tgtagcaatg ccttcacctg ttaggtaagc gcgatactta
    20581 agcattgggt ccttttcctt ccactcatca acctcttctt tggtgcggta tttgccggca
    20641 tcagcagttg aatgaccaaa ccaacggtaa gactcaacct caacaacagc aggaccattg
    20701 ccaccgcgaa catgctcaac agccttactc atggtttcat aaactgccat cacatcgttg
    20761 ccgtcctcac aataaaagcc tggaatacca taagcctcag cacgcgtgta gaggtgaggt
    20821 gtatttgtgg cattgttaat gctcatggaa atcccatagc ggttgttaat gataaagaaa
    20881 atcacaggaa gcttccaagt tgctgccata ttgacagact catggaagga gccctcattt
    20941 gttgcgccat ctccagaaaa ggccacaacg atattgttgg tccccttgta ttgctgtgtc
    21001 aaggcagcac ctaccgcaag ggcatagcca cctccaacga taccatttgt tccatagttt
    21061 cctttttcaa aatcagccaa gtgcattgag ccgccgcgtc cctttgacac acctgttacc
    21121 ttaccggcta gctcagccat cattttattg aggtccatat ctttagcaat agattgccca
    21181 tgcccgcggt ggtttgaaaa aataatatca tcataggtca aatgtgccac agcgccaacg
    21241 tttgctgcct cctcaccaac tgagaagtgt gtcatgccct gcacaaatcc acgacggaca
    21301 agcttattaa tacgtgaatc aaattcacga atacgctcca ttttaaggaa catatctaaa
    21361 tgttgttctt tagaaactgt taccatttcg gcctccatat tatcatatta cttcctaatc
    21421 ataaaacttt tcttcacaat ttgcaaggat tttaatcgct ttctttgtga ctataaaagc
    21481 ttttttaaga cgttttagtt tgtggtttca caagctagat tgttatagca tctgttacat
    21541 ttatatataa cagattgaaa aatgagtcag tgtttattca gggaggtcaa gcacctattg
    21601 actttgatag tcagaaatat catcactctt taagaggaaa ataggctcta aatgacctgt
    21661 ttcttctagc acaatcatga tcacctacca aacgaacgct ttgcttgcct cgctccgata
    21721 gaggcgaaat gaactaaaaa tcgcataact aaaaatgcct gattttacct gaaaatcaga
    21781 catttaaaag ctttaagaca ttagactcag gctctaatta taatcctcta agaaaagcct
    21841 gctaccttgc actacccaag aatagcaagg caatttcatt atctcaccag gctactccag
    21901 ctgtcctgca atgtcctccc actccagcag caaggtctcc tgtttctgat taagctgatc
    21961 caactctttt tgccagtcta tcagttgagt cgtatcattt gatactagca tttgagcttc
    22021 tatagcctta gcctgtgctt ctagcccttc taaggtctgc tcaatctcct caaagcgcct
    22081 tgttaagcga cggtattcct tttggctggc cttttgaagc tgataatcag ttacagcagc
    22141 ttctgctaca tcagtctcta ctacgtgatc tgcagcagct agacgggcta attcctcccg
    22201 ctctgccttt ttttctacat aatagtcgta gtcccccaga tagagtgttg agcctgcttc
    22261 agttatttct aaaaccttag tggccactcg gttgataaaa tacctgtcat gactaacaaa
    22321 caacaaggtc ccatcaaagt caatcaaggc attttctaga acctctttgc tatcaatatc
    22381 caggtggttg gttggctcat ctagaatcag aaaattgtcc tttttcatag ataattttgt
    22441 taagagcagc cgagcctttt cgcccccaga tagcatggcc acagactttt tgacgtcctc
    22501 accagaaaag agaaaggcac ctaagcggct gcggatctca agctcagctg tcgttgggaa
    22561 atcacgccaa agctcctcca atacagaatt actaccagtc agatgagatt gcgtttggtc
    22621 ataatagcct gtttcaacat tagtcccata atggcatgtc cctttaatca aaggaatctc
    22681 tccaataatg gatttgagta gggttgactt gccaatacca tttggcccaa caatagcgat
    22741 tgcatctaac ctacggacat ctagatgaat tggctcagct aaaatatggt cattgtagcc
    22801 aatagcggcg tctgtcacct gcaaaacaac atttcctgag ggcttatcaa tctgaaaagt
    22861 catactagct gatttgcgag agctacttgg cttgtctaag cgttctagct tttctagctg
    22921 cttgcgtctt gcctgagcac gcttggtcgt tgacgctcga acaatgtttt tttggacaaa
    22981 atcctctagc ttagcaatct ctttttgctg cttgtcataa tgcttctctt ctgctgcaag
    23041 cttttcagcc tttaaatcaa taaagcgtga gtaattacca acatagcggt ctaagctatt
    23101 tttagtcaga tcaagtgtga tggttgcgac cttatccaag aaatagcggt catgactgac
    23161 aatgatcaag gctccctgat aatttaccag ataatgctcc agccaggcaa tggtttcaat
    23221 atctaaatgg ttggtcggct catcaagcac caatagctct ggcttttcta gtagcatttt
    23281 tgccagggcc aaacgggtat tttgcccacc agaaagctct gagattttca tttcccacat
    23341 gctttcgtca aacttaaagc catttaaaat agctcgaata tctgactcat aggtgaagcc
    23401 atttcgcaag cgaaagcttt ctgacagccg gtcatagtct gacatgagct ggtccagagc
    23461 ttgccctgat cgactggcca tatcagcctc catttgcctt agtcgctgct catcaaccct
    23521 caattcagca aataccttta gcatttcctg ataaatggtc ttgtcagact caaatcggct
    23581 attttgtgcc aaataagata gggttaagtc cctttttcga ctaacctcac cgctagttgg
    23641 ctcttcttct ccaactaaaa tcttaagaag ggttgatttg ccagcaccat ttggcccaac
    23701 caaggcaatg cgatcacgtt caccaacctg cagcgatagg ttttgaaaaa gcacctctcc
    23761 tgaaaaagag cgctcaatgt tatttccttg taatataatc atacccttat tgtagcaaaa
    23821 aaatgccctt ttggggggca cttttagtta tttttacagg taagataaga ctcatcaaca
    23881 agctaaagac ataagcctta ggctaacatc gcttatcacc cttagtggta tttatctgat
    23941 gagacaaact gctgcttgaa aaaccagtgg gttgacctgt tagcgtatcc aacaatcgca
    24001 ccacctgctc agttatgctt gaaatgctat tagccagtga ggaatcacta tggttcgaat
    24061 aataaatcaa accaaaaata agcaatacca atactattag ggtctgcaaa cagcctctga
    24121 caagctgcca gacaagcttc agcagaagct ttgggaggca taagaggata gtcagtagtt
    24181 ttttcatcgt aataagccta aattctttcg tttaggatag cctttcttcc ttgtggtaag
    24241 caatcggcag ccaatctaat agggcctcta gctgctgatt ccaataatac cattcgtgcc
    24301 tgccatgatc cttacgataa tcaatagtca agccaagcct tctcaactca gcaactgcct
    24361 tttcattggc ttcaaacaaa aagtcctcat agccacacca agcgtatagc tgggtttgac
    24421 catcactttc tgctgctata cttgtcaaat aatgcttttt gatatcagga gcattcaaat
    24481 ctccaaaaac accctgccaa taaggcagct cacctatacc ttgctgtaat agcatttccg
    24541 gcgaaaaatg caaggcccca gaaaaggaag cagcatagga aaagcgattg ctttttaagg
    24601 cccatttaaa ggcaccatag cctcccattg acagcccagc aacaaaggtt ttttcacgct
    24661 tagtggtcat attaggaaag aaagaagcta atagccgagg aagttcctct gcaatagctt
    24721 ggtaataatt cataccgtag gtggtatcgg tataccagcc taaatcagtc gatggcatca
    24781 ccacgattaa attggtatgg cgaagcagcc tttcaatatt agtccgcttt tgccaggaat
    24841 tttcatttcc tcccatacca tgtaacagat aaagaactgg aatatcttgg tagccttgct
    24901 cttctgggct aagctcagac tgatcagggt agatcacctt gacatgtctt tccatagcca
    24961 agatctctga atgatactca atgctaatgc ttgccatcag ctcacctcct ttttaatatc
    25021 accaaagcat aaggaaagcc cactcttaag acctaaaagc cagatcctat ttgaccagct
    25081 tttaggcagg gctgtatctg tattaacgga cctccataac aaccggaaga atagctggcc
    25141 gacgcttggt ctgctcaaat aaaaaccttg agagctcctc tctaacagag cctttcaatt
    25201 cactccaatc aaaatgatcc ccttgcagat aattgccaac tgttgtgttg accaattcag
    25261 cactttctcg taaaatatct ctgctctttt tcacatagac aaatccgcga gtgttgacct
    25321 tagccttaga gataatacgt ttttcctttt tagatactgt gatcgcaaca ataaaaatac
    25381 cgtcctctga taagacctta cggtctctca aaacaatatt gccaacatca ccaatggcat
    25441 ttccatcaat catcacatca ctagcaggaa ccgcaccctc gtgtaagaag ccatcctcat
    25501 caagcaccat gatgtcacca cgcttcataa tatgaatatt ttcaggtagt ataccagcct
    25561 cctcagctaa atgagcatga gcagctagat cgcggtattc accttgaatc gggaacaggt
    25621 attttggttt gacgagatta atcatcagct gcaggtcacg cgcattggca tgtccagaaa
    25681 cacgtaaatg ctgcgtgatg agcttaacag agccacctgc tttatagata aggttttcaa
    25741 cacgagcaac cattgcttcc ttggcagcgc ttggcgttgt gacaatgtaa accagatctc
    25801 cgtccttgat ttgcacgtgg cgatgacgcc ctattgccat tttctgtagg ctattaatcg
    25861 gctcacccat acgtccagcc tccagaacaa tcaattcgtg atcctcaaac ttagacatat
    25921 cctttggctt gattaatagc ttttcatcag caatcactag ctttttaaga cgaagtgctg
    25981 ttctgacaat attttcagcg tcagtacctg tcagtaccac tcgcctgcta taggctgctg
    26041 cagaatcaaa gacctgctgg atacgaacaa gatttgaagc gacagctgca ataataatcc
    26101 gcccgtcggc atgagcaatc accttatcca tctcctcgcc aacctcagct tcgctggcag
    26161 tctgctcatt gcttgtggca ttggccgagt cagctaatag ggctaacacc ccttcttttc
    26221 caatgtctgc caagcgagct aggtctgtct gatagccctc acgcgaagcc tggtcaaact
    26281 tgaaatcacc tgtatagaca atattcccct tatcggttcc aataaccacg cctaaacttt
    26341 caggaataga atgtgttgtc ttaaagaagg aaaccaagcc atctttaaat tcaatttctg
    26401 tgtcactgtc gaccacatgg aaattcttaa atctcttggt gctattattg gccttgacaa
    26461 acaattttgc tagctcgatg gtcaattctg aaccaaatac tggcactgga acctccgcca
    26521 acaggtaagg caaagctccg atagcatcag catgcccatg acttaaaaag actccctgaa
    26581 ccttgtcctt gttttcaatt acataatcaa gacttggaat taccaaatct acacctagct
    26641 gttctgtttc agggtatttc aagccagcat ccaaaatgaa catggaatcg ttaatctcta
    26701 ctagatagaa gtttttcccg tactcacgta cgcctcctaa tgcaataatg tttatatcag
    26761 tcatgatact ccttttttta tattagttat tacaaacggt ccttactggg taagtcgaat
    26821 tactgtcttg cagctaagct gcactctttt acagtatatc atattttagg gcttattacc
    26881 tcaaattgcc ttgagacttt ctcaatcttt tcaatagatt atcaaaaaag ccaagggaag
    26941 gctttcattc caatggcttt tagagtattt attttagtca aaaagctggt aataatcagc
    27001 aatggtcatt tgagattttc tcttctgatc aaggtcttga atgattttac catttttcat
    27061 cacaatcagg cgattaccat agttaagagc gtcctccatg tgatgcgtta tcattaaggc
    27121 tgtcaagcga tccttagcta caaaatcatc agtcaaggcc attaaggctt ggctggtctt
    27181 agggtctagc gctgcagtat gctcatctaa tagtaaaagc tctggtcttt ttagggttgc
    27241 catgagtaag ctaagggcct gtctttgacc gcctgataag agaccagtcg gagtctccag
    27301 atgattttcc aagccatttc caactcgctt gaccaagtca gcaaagtctg ccatataatg
    27361 gctaatcctg cgtgatgaca agcctcgcct ttcccctctt tgccttgcaa tcaaaaggtt
    27421 ttcagctact gtcattcgag gtgctgttcc cattttagga tcctgaaaaa cacgtgatag
    27481 gtagctagct cttttttctg ctggcaggtg cgtcacatca tgccctaaaa gcttaatttg
    27541 acccttgctt aacaatagcg tcccagcaat cacattaaaa agggttgatt taccagcgcc
    27601 attcccacca agaatcgtta aaaaatcatg ctcataaatg gtcaaggaaa catcatctaa
    27661 aatagcctta gtctcatcaa agccattatt gacttcgaca gtagcgtgaa ttaattcaat
    27721 aatttttctc atcgtgataa gctagcctcc ttaataattg ctttttttag cacaggcacc
    27781 atcaggcaaa gtgctaatat aatggcacta aatagcttaa gataatttgt attaaagcca
    27841 agagcaataa ctactgagat taaaaattga tacaggatag aaccaaccac aatggctatc
    27901 aagcgctcaa gcagggttag gcctgtagaa tataaaacct caccaacaat aatactcgca
    27961 aggccaatta caatcacacc aatccccttt gaaacatcag catagccatc ttgctgacta
    28021 accaaggcac cagataaggc tatcaaggca ttagagatcg ctaagcccat aagctccata
    28081 cgatcagtat gaatcccaaa gctcttagcc atatcccgat tatctcctgt ggcaatataa
    28141 gcctgaccaa tattggtgta aagaaaatac attaacaaaa aaatcaccaa tgtagctaca
    28201 accaaaccag ctaccaacac attggtgtca gctgcaaagg gaaggtagtc ctgaatgcgc
    28261 ttgatatcat gcaagcccaa attggccctg cccataacca taagcataat ggaatggcag
    28321 gaggtcatga ctagtatgcc ggcaagaagt gttggtatct ttccttttgt gtataacagg
    28381 cctgtggcga agcctgccaa ggcacccgcc agcatagcag ccagagtagc caggatagga
    28441 tttaaaccga gattgagcag agttactgct acagcacctc ctaaaggaaa ggacccttct
    28501 gttgtcatat ctgggaaatt caatattcta aaggtcaggt aaatccccaa gccaagaatt
    28561 ccccataaca agccttgtga tacagatgaa ataatcatat gaactccttt tctattgctt
    28621 acctgtaagg tcagaacgct tcagcaggtc ttttgagatc ataagaccta aatcccttgc
    28681 tgcctttaga tttaaaaatg gcttaccgtc atcaactacc tcgacaggaa cctctgatac
    28741 ctcttttcca gccataagct gcagcacctg cctagctgtc tcaaccccta attggtattg
    28801 actttgtgaa atagaagcaa gactcccttg ctcaaccatt gtatcaacac ttgagtagac
    28861 cggaagctgt gctgcatttg aggcaacaat caccgctgaa aaagcactgg caatagtatt
    28921 atcctgtggg ataaaaacag catctacctt ctcagtcatc acagacatgg tcgtggtaac
    28981 ctcatttgtt gaggggacag cgtaagctag aacctccaag ccttgctttt ctgcaagagc
    29041 tgtaaagtcc ttgacctgtg atattgaatt gtcctcactg cttgcataaa ggacaccgac
    29101 ccttttgacc tgaggggtca tctccttgat cagatcaacc gtctgtcgaa caggaacctt
    29161 atttgataag ccagtaacat ttgcctcagg cctgtctaag tgcttgacta atttagcacc
    29221 aactggatca gaaatagctg acatcacaac cgggatagtc ttggttgctg ctgctaatcc
    29281 ttgagctgca ggcgttgcga tgccaacaac aatatcgttt gttttgacca gctgcttgct
    29341 catggtctga atcttacttt gatctccttc tgcattcata agggtaatgc tgaccttttg
    29401 ctctggctga tgatgcttct ttagctcgtc tttaatgccc tgtgcaatct ggtcaagcgc
    29461 ctcatgagta accagctgca atataccaac cttaaccaca cgcttgctgg ctaactgtgg
    29521 ctgttttttg ccctctttta gcactagcga agcagcaacc attaaaaaga gtgcaatgac
    29581 tgttacgata agacctttat gtttcatgtt ctacctctta atttccattc ttactccgtt
    29641 gctaacattt agagtactca caaaaagaaa aaacgcttag taatcagcta ctaggcgctt
    29701 tttttgaaat ccaatgtcag cgcatagata cctttttaga agtactctaa aagtcgtatc
    29761 tatgctaacc cataaacaca actttatcta tgccagcttt gccaatttat catatgctgt
    29821 gtttgcttca tcttggattt cctttcttgt ttttttacat tataacctaa aagctcaaaa
    29881 atacaagagc atttgaacat atttttccat tattttttgt ggtataatga aagaattaga
    29941 actcaggagg gagaaaccat gtcatttgac ggctttttct tacatcattt aactcaagag
    30001 ctcaaccata gtattgttaa tgggcgcatt caaaaagtca atcaaccctt tgataatgag
    30061 ttggttctga ctatccgtaa ccatcgccaa acttacaagc tcttgctctc agctcatccg
    30121 gtttttggac gcattcaact gacccaaaca gactttcaaa atcctcaatt tcccaatacc
    30181 tttaccatga tcatgcgcaa ataccttcaa ggagctatca ttgaaggctt tgagcagatt
    30241 gataatgacc gcatcatcga aatgaccgtc tctaacaaaa atgagattgg cgatgccata
    30301 aagacgacat tgatcatcga aattatgggc aagcacagca atattattct ggttgaccgt
    30361 catgaaaaca aaattatcga gtctatcaag cacgtcggct tttcccaaaa ttcctaccgg
    30421 actattttac caggatcagc ctatatcgag cctccgaaaa caactgctgt caatcctttt
    30481 acgatctcag atatcgcttt atttgaagtc ctgcaaacac aggagttatc tgctaaaaat
    30541 cttcaaaagc atttccaagg gcttggccga gataccgcac aagagctatc cagtctcctg
    30601 acaactgata agctaaaacg gtttagagac ttttttcaaa gacctagtca gccaagtcta
    30661 actcagacct cctttgctcc agttgccttc tcaaacacac tgaagacctt ccagaatcta
    30721 tctcagctgc tagattatta ttatcatgac aaggctgaga gagatcgtat caaccagcag
    30781 gccagtgacc tgatccaccg cgttcaaaac gaattggaaa aaaatcgcag caaactgatt
    30841 aagcaagagg ctgagctgct agccactgaa aatgcggagg actttcgcca aaagggtgag
    30901 ctcttaacaa cctatctgag cctggtgcca aatgaccagg attcagttga gcttgataac
    30961 tactataccg gccaaaaaat aaccattgca cttgataagg cgttgactcc caatcaaaat
    31021 gcccaacgct attttaaaaa atatcaaaaa ttaaaagaag ctgtcaagca cctctcaggt
    31081 ctcatcgctg acacgcaaca aaccatcgct tattttgaaa gcgttgatta caatctatct
    31141 caggcaacga ttgatgaaat tgaggacatt cgagaagagc ttattcaggc tggctttgtg
    31201 aaaagccgta agcataacaa gcaccacaaa cgtaaaaagc cagagcaata cctggcttca
    31261 gatggcaaaa caattattat ggtcggacgt aacaatctgc aaaatgagga attaaccttt
    31321 aaaatggcca aaaaaggcga gctctggttt catgctaagg atattcccgg cagccatgtg
    31381 atcattaagg acaatctaag cccaagcgac gaggtcaaaa ctgatgctgc tgaattggcg
    31441 gcctattatt ctaaagcaag actttccaat ctcgttcagg tggacatgat tgaagccaaa
    31501 aagctgcaca agccaagtgg tgcaaagcct ggctttgtca cctatacagg acaaaagaca
    31561 ctaagagtga cacctataga aagcaagatt caagccatga agtgctcccc ttcagcctct
    31621 tcctcatagg actacagcaa taaagataaa aaaagctaca gcctcacact tggagatagg
    31681 tccagtctta aagctgcggc ttttttatca ttacttgtta atcatctctc aaatcatcta
    31741 agaagccttg catatgaata tcatctggaa cctgctgcaa ataccttttt gcctgcttaa
    31801 ctgcttgatc agtatagccg aattccctta ataaataagc ataatcctgt aaaaagtcag
    31861 gattttcttt taggtctcct tcgatatctt tatagatagt gagggctttt tcttgctgct
    31921 ccagagcctg ataggccttg gcaagattcc atttagttag cacatgatca atctcctcat
    31981 gctcaagagc aatgacctcc tcaaaacgct ccatatccaa gtacaggcta gataagcgca
    32041 tgatgacctc ttcgtcatca acagctactt ccttggccct gagcaaatac cgctctgagc
    32101 cagctggatc atgcaattca aaggcaagct gtgaagcaag caacagcagc tgggggtcaa
    32161 aggcattttt acgcagaccc tgctgaacta ggcgtaaggc ctcttctgtc cgatgctcct
    32221 cacgcaagct catggcatag gggtactcgt agcctaaaaa gtctgcattc atcgtttcta
    32281 attgcttgaa atagagattg gccttttggt aagcagcctg atcatataaa atcgtcgcca
    32341 gctcaaacac tgtctcatcg tcatactcaa tggcaagagc cttttcaaga aactctacag
    32401 cagcttcaaa tttccctaaa taagcatagg cacgccctat gcgctggtag gttgagatac
    32461 ctgtcagctc aagaatgtga cgattatcaa gcctagcata ttgctcaata gcctcgctaa
    32521 agtgctccag agacatctcg atttcggcta agccaaagat cactatcggc tcctgactca
    32581 attcagctgc ttgaagtagc ttctcacgcg ccacatcagt tagcccctcc aaatcataaa
    32641 gatcagccat gacgagcaga gcagacaaat aatcagcact atcctctgga atcctatcaa
    32701 ggtacataaa ggcctcttca atgacattat cctcagctgc aatctgagca agattaatat
    32761 tgacctccgg ataagcctca cagacctgca aataaatcgt cttagcatgc agtaaaaaac
    32821 caatactctc taggtattct gccaaagcca acaaggtctc agcatcgtcc tcctgcaagg
    32881 ctctttgaaa atagctttct gcctgctcta aatcctgttg ctctagtgag gcaatcattt
    32941 tttcactatt taacatcttc agcgaccctc tcagcttctg taggctcttc ctcatacagg
    33001 cctgtaatat ccttgtacca atcaaatagc tccttcacaa caaccttaac agaagcataa
    33061 actggaatga caagaaagac accccagacc ccaaacattg accctgctgt caataataaa
    33121 aacataatgg taatcgggtg aatgctcagc ttatttccaa gcactagcgg cgcgacaaaa
    33181 cgtccttcaa tcgtttgttc aataacaaaa ataatcaaca ccttgatcag catcaagggt
    33241 ccttgcacca ttcccataat cactacagga atcatggcta aaaagctccc cagataagga
    33301 atcatattaa gaaagcctgc aataatacca aaggtaatag aatagttcaa accaacaagg
    33361 ctaaacatca ctgaaaacat gagaccaacc acaatcgcaa cggtcacctg tccctgcaca
    33421 tagccagata attgcttgtt gatttctcct aagacacgtg ccataggctg gcgcagctta
    33481 atcggaagca cattgaccaa accatttttc atatggccac tgtcacgcag aaaataaaag
    33541 agaataaaag gtgacatgat gattgcaaca gtaatacggg caatagctcc agcaaaattt
    33601 cctgcccaat caatagcatt tttagagaag ctttgcgcat aatctagagc cttttggctc
    33661 atactagtca gcatatcctg caggttggac ctgtagctaa ccagccattc gttttcaagt
    33721 agcttattag cctctagatt gaccttggca acatatttgg gaaggtcttc gacaaagctc
    33781 cttagctggt cttgaatcat agggataaag ccagaaatag cccagaaaaa taggagaatt
    33841 actaagccaa agacaataaa aatagaggct gtgcgatttg gacctagctt ctcaaccata
    33901 tcaactaatg gcttggtcaa ataatacagg atagttgaga taaccagcgg cagcatgata
    33961 atggccaaaa atgacaagat cggtgtaaag aggaaggata tttttgtaaa gacaaaaata
    34021 gtcagaaaaa ccagcagcgt gattaacaaa accatcaccg cctgattatt taaaaaccat
    34081 ttgtaaaata gactatcatg atgattaggc ttagaatgca atgacattaa tggtatcgtc
    34141 ctttcttaat tgtggcatca ttctgatgag agcttttagg ttagttgact taataaaagg
    34201 tgactgtttt ttccactagc ttgttgtggt catcatacct aaatttagca gaaaaaaacg
    34261 gccggtcttc cagtatccac ttgaaaatgt cgtaatctcc ctcccaggtt ggcttttcca
    34321 gcacctgatc atagggaacc cattctaggg tcccttctct ggactcctca tcagcaatta
    34381 agtcaccttc aaagtctgtc accttaaaca cgtaagtata ccaatcatgc cctggtgtaa
    34441 aatcaggaaa ggtaatcact cccttaaagt ccattgcttt taccagcagg tgagtttcct
    34501 ctaaaatttc acgtctggca cagtcatcag gagattcgcc tggctctaat ttgccaccaa
    34561 ctgaaatcca cttaccttgg tgaacatcat tttccttctt gttgcgatgc agcagcaata
    34621 aagcctcacc gttatcaata taacaaatcg ttgctaactt agtcattcat acccttcctt
    34681 tgtttagttg ttactattat accaatctct gagaaatatg ccatcatttt atcatttaag
    34741 cacatcaaac aagaaaacca caatcactac aactcttagc cctgtactag caaaaaagcc
    34801 ttgataaggc aacgtctgct gactcatcaa gacttatcac tatttaacga atcacttcct
    34861 gtgtcttagc gtaattggct tcaactgctt ctttttcgga acgccaccaa tcctgatgat
    34921 cagtatacca ttggatcgtt tgctcaagtc cttctgaaaa atcagtaaac tgtggctccc
    34981 agccaagctc ctgacgaagc tttgtcgaat caatagcata gcgtaaatcg tggcctgcac
    35041 gatccgttac atggtcataa gcgtccttag gctgccccat tttatccagg attaattcca
    35101 gcacttcctt attatttttt tcgccgtcag ctccaataag gtaggtctca ccaatacgtc
    35161 ccttggtcaa aatggcccaa acaccagttg agtggtcatt ggtgtgaatc cagtcacgaa
    35221 cattctttcc ttcaccatac aattttggct tgataccaga caagatatta gtgatctgac
    35281 gagggataaa tttctcgata tgctggtagg gaccataatt atttgaacag tttgaaatgg
    35341 ttgccttcac gccaaaggag cgaacccagg ccttaacaat caaatcagag gctgccttgg
    35401 ttgatgaata aggtgacgac ggattatagt tagtatcagc ggtgaatttt tcacctggcc
    35461 cctcaccatg acctggcaaa tcctcacgca gtggcagatc cccataaacc tcatcagtgg
    35521 acacatgatg gaagcgaata tcatatttac gagccgcctc taagagtgta taagtcccaa
    35581 cgaagttcgt gtaaataaat ggacttgggt cattgagtga attatcattg tggctttcag
    35641 cagcatagtg gacaatagca tctgccttag cggccagctt atctaccaat tcagcatcag
    35701 caatgtcacc aacaaccaac tccacgcgat cacccaaaat ctcctcaagg ttggcacgat
    35761 tgccagcgta ggtgagctta tccaaaacag ttacgtgaac ctctgggtga tggttgtaaa
    35821 cataatgtac gaagtttgaa ccgataaagc cagcgccacc ggtaacaata atgtttttat
    35881 attcagacat gttttttctt ttcctttgtt ttcagctatc agcactcaaa atgcagctta
    35941 atccgacagg caagctcagt taccagtgaa aacagcgact aagctgcctc acctcattgc
    36001 tcctaccatc cataaggtcc ttcctatcag aaggatacag agacactccc atcaaaagcc
    36061 atagcttatt tcaaatgcta attatgataa atcttcttgt ctcaaaggct taacggcctc
    36121 taggaaggga tggcttttat ctgcttctga aacctctgct tgttcaagac tttcccacgc
    36181 aatcccaagg cttgggtcag cataattaac aaaggcatat ttttgcttga gctcaagcgc
    36241 ccaataatca ttgaccagat aggtataagc caccttatca gtcagtactt gaaagccatt
    36301 agcaacacct cgagggacaa aaatcccctt tgaagcgtca atgactgttt gataggtatg
    36361 cccaaagcta tcaccctcac gaagatcaac ccaagctcca agaaccttac cctcatcagc
    36421 aacagagatg tacttgtccc aaggctctgc atgcaggcct cgaagcacat gcttgcgcga
    36481 aaatgaaata ttgttttgca gcttacctgc ggcaaaaaac tgctcaggaa agcctagagg
    36541 aatcattttt tccttttgaa aattttcctt aaaccagcca cgattgtccc ctcgaacagg
    36601 gatatcaaac tccaaaagtc caggaatggc ttcaatttcc cgacaggcta aggctttatc
    36661 aaaaaattgt tctgtcatca agcttctcca atcaaccgca gcaggtactg cccgtattcg
    36721 tttttcttaa gcgactgcgc tagctggtag acatcttctt tagtgatata acccatgcga
    36781 taggcaatct cctctaggtt ggccacctga gcgttttgca agcgttgaac tgtctcgatg
    36841 tattgggcag cctccagcag gctttcatga gtgccagtat ctagccaggc aaagccacgt
    36901 cccatcaact caaccgatag gtcgccacgc tctaaatagg ctttattaac atcagtaatc
    36961 tcaagctctc ctctggcact tggtttaatg cttttagcaa tctcgactac atcattgtcg
    37021 taaaaataaa ggcctgttac agcaaaatgt gacttaggaa ctgccggctt ttcttcgata
    37081 gaaatggcat tcatctcatc gtcaaactcc acaaccccaa aacgctccgg atccttgacc
    37141 tgataaccaa aaacagtggc tcctttttcc ttagctgctg ccttttggag cattttcgta
    37201 aggccgtttc catgatagat gttgtcacct aaaatcaagg caactcgatc atcaccaata
    37261 aactcctcac caatgataaa ggcctgtgct aagccgtcag gacttggttg ctccttgtag
    37321 gacaagctta tcccaaactc tgagccatcg cctaatagct cttcaaatct tggaagatct
    37381 tggggagttg aaataatcaa aatgtctcga atccctgcca gcatcagtgt tgataaggga
    37441 taataaatca ttggcttatc ataaattggc atcaattgct ttgaagctgc acgagtaaga
    37501 gggtacaagc gtgttcctga tcctcctgcc agaataatac ctttcatcgt agctctcctc
    37561 attttataat acgtcactat tttatcattt tttaaaaaca gtgtcacttt ttatcattaa
    37621 tccgacgaat ataatgatga atcgggtatt gactagtatc taagctagct ttttgcccca
    37681 aaagcagggc aatcagctgc tgagcaatca aaggacctag ggtcaagcca gatgagccta
    37741 gaccgcttgc ggcgtaaaca cctggtagct gaggtacctg cccaaaaaat ggagaaaaat
    37801 ctctggtata ggctcgaatg cctacgcggt aagaaacatc agaggcagaa ctcagcttag
    37861 ggtaataggt caaggcctcc tgctccaagg cctctaaaac agctacatca ggctcaaggt
    37921 catagccctt atcattttca tgactcgctc ctacagacaa cctatcatgc tcaaagggaa
    37981 taatatccag ctccccctct ggcatgacca ctgcgtagtt atctgtagtc acattcgcaa
    38041 tgtgataatc aatgagctgt cctttttgcg gtcgaatatc cacctgatag ccaagtggct
    38101 caagcaattc tggcagccaa gcaccagcgg ctagaatcag ccgatcaaag accataccat
    38161 caacgagata gccttgcttt tctatgctta tgccaacacg ctttttaacc acctgatagc
    38221 cactagcttc aagcaaacac tgacataggt ctgccccatc aacacgtgca gccccagaag
    38281 cccataccag ctgctcaaaa ccctgtaaat caggaaaatc aaccctaatg tccgaacgac
    38341 accttatcgc caaatctcca atcaaaggcg actcttgctt gcgtctaatg gccagctggt
    38401 agagctcctc tagcttgtcc tcattctttt ttaataaata aacaccagtc tgcttataaa
    38461 aatgtgtaga aagcccctct ttttgcagct ccttgattaa gtcctgataa caatctgctc
    38521 ctaaccgagc cagctggtac caagccttat tccttctttt tgaaaaccaa gggcagataa
    38581 tgccagcggc tgccttagtt gcttgaccat taccatcatc aaaaatagta acctgctgat
    38641 acccttgttt ttttaaataa taagcggcgc ttgaacctac aattccagct ccaatgattg
    38701 ctatcgttgt cattgccgtt tccattctat catactgctt accaagcata ggccatactc
    38761 agtcatgcta tagatgacta aagggatttg ttgacgcctt gctagccata atggttactt
    38821 gccagccttc ctcttttttc caagcctgca tcttggcaag tagtttatca ataaataagg
    38881 actcgatgtg atgccctgga tcaattgcca gcaggccttc tgtcagcatt tcctgtgctg
    38941 tgtgataata aatgtcacca gtaatataaa cttgagctcc cttagcaagc gctgcctgat
    39001 aaaatttatc accactgccc ccacaaatag ccactcgcga aatcaaaggg ttttgaccag
    39061 tatatcgaac cagccgaacc acatcaagcc caaaggcttc tttaactgta agtcctaact
    39121 cctccaagct ttgctctgct acatttccga cacgtccaat accataccca tcttgcgtct
    39181 caaccaatac ctctgtctgc tcaatgccca acagctcaca aaaccaatcg ttgagcccgt
    39241 cagagacaat atctatattg gtatgactga catagacaga aatatcgtgc ttcaccagct
    39301 caaggacaat atctcgctgt ggcgaggaga ccaagtcctt caagccctta aaaataggag
    39361 cgtgcttggt gataatcagg tctaccttgg ccgcaatagc ttcggcaacg gtattttctc
    39421 tcacatcaag ggtgatcatt acccttttga cctccttatc cagagagcca atttggaggc
    39481 cacacacatc tcctgacatg gatagctcaa gcggacaata gctttcatat ttttcgatga
    39541 ttgttctagc tttcatgact gatgacctcc tcaatcgctt ttattttttg agaaatgcta
    39601 gcgcgttcaa caggcttcgt tgctggcaca caagacaggg catagacaag cttatctcgc
    39661 tctttttgcc atttagccac aaagactgat gacctttcct gagacaagaa aggaccaaag
    39721 cgctgctcct gatctgttag actttgttga ccaggctctg caacaatgat ttcataatat
    39781 ttgccatttt ctgtcatgat ggtttcagca ctaatacaaa aagcattggc agatagccaa
    39841 gcacgcagct catcctctcg attattgggc tgtaaaatca agcgctcaat cccttgcagc
    39901 ttttccttac cagccgctaa aatgtcagct attaaacgcc ctcccatgcc acagatggtt
    39961 atgcagtcta cagcatctct cgcctcaaag gcagctaagc cattagccag acgcacctca
    40021 atatgctctg tcaaaccata ttgtgacaca ttttttaggg ctgatacaaa aggtcccttg
    40081 accacctcac ctgcaatcgc ctcttgaata tgctcggttt caaccaaaaa aataggaaga
    40141 taagcatgat cacttcccac gtctaaaagc ttagcaccat cagggacata ggatgccaca
    40201 tggcgtaagc gctttgataa atgactttcc attttcttaa tccttctaac aactaatcgt
    40261 atcactatta tagcaaaata cagaccaatt aaaaagaaag ccacatcaga ccttcttttt
    40321 accataggta gtcttgtaat agctgcaata gctctgtact gggcaggtat cacacttagg
    40381 atgcttagcc aagcagtgat agcgtccaaa aaagatcaaa cggtggtggg tgatgatcca
    40441 atccttctta ggaagcttgg ccatcaaatc agcttcaatt tcagtaacat cggcatctgg
    40501 ggcagaaatg ttcaagcgct tggcaatcct tgacacatgc gtgtcaactg cgattgcagg
    40561 gacaccataa atctctgcca agaccacatt agcagtctta cggcctactc ctggtaagga
    40621 ttcgagctcc ttatgggttt ttggtacctg accatcaaac tgtgtcagta gctgctgagc
    40681 tgtcttgatg atattttttg ccttattttt atacaagcca attgtcctta ggtgatcctc
    40741 aacatctgac acatttgcct gagccaaatc tgaaagctct gggtagcttt gccacagctt
    40801 aggggtaacc ttgttgactg ccttatcagt tgtctgcgct gataggataa ccgtaataag
    40861 aagctgaaag ggcttttctt ggtcccaatt cagctcgccc ttagcctctg gaaacatctc
    40921 accaatgatt gatagaacct tttttaatcg ttctcttcct atcctcatta gttactccaa
    40981 aggttcatcg ccgcaagaaa atcatctgaa accgtcactt cagacgccgt catatcctct
    41041 ctggcacgct ttttttcctc aagctgcctg aggcttgtaa ttccctcctt gcgccaattt
    41101 cttagaatag cctgaatata tttccaattg gtttttccat taaagacagc ctctctcagc
    41161 gcctcacgca ctaaatccag atctgtttgg tcatcatgaa tggttttttc caaatcctct
    41221 agctccatcg gactcaaaaa acgacccagc tcacgctcaa actcatcaac aagaagtttc
    41281 aattggttgg tgttttgctg ttcatgctca cccttttcat cacgcgccaa tagctggtct
    41341 aaagtgacta atacaggact agcatcaaaa atgatctcaa tctctccagc cagctctatg
    41401 gttttcatat ctaataaccc ctgactggtc aaggaagaaa tagccttatt cacctctgct
    41461 acagacttac ccaaggcatt agcaatctga ctaggtgcca attcgtcaag cctagtcgta
    41521 ttttggagat agaaaaactg ccaaaccaaa aaatcgtctg agctcttaaa aatatccttg
    41581 taatgaaaca gtaaggcagt tggaaggacc aaattgccag actgataatg ctctaaaaaa
    41641 ctcataattc ccctgccaaa cgtaatagcc caacctagct tttaatcagt actgccatta
    41701 gcaagcactg attaaccagg aaaatgcatc aataccttac aatcgtaatc accaatagcc
    41761 tgacgaccat tcaagccgtc cagctcaatg agaaaagcgc agccagcaac aatgccgccc
    41821 agcttttcaa ccagatcaat agtagccttt actgtaccac ctgttgctaa taagtcgtcc
    41881 acaataagga cacgttggcc cggcttaata gcatcagcat gcatggtcaa ggtgtctaga
    41941 ccatactcct tttcatagct agcagaaatc acctctcttg gcaatttacc cggcttacga
    42001 acaggagcaa agccaattcc tagctcaact gcgaccggac agccaataat aaagccacga
    42061 gcctccggtc caacaatcat gtcaatgtcc ttatcgcagg catattgcac aatctcacga
    42121 atagcatagc tgtaggcctt gccactagcc attagcggcg aaatatcacg aaaggtaatc
    42181 ccctcctttg ggtaattctc aattgaagca atatattgtg ttaaatccat cgtaaaatag
    42241 tctttctaat gtcttttaaa ttaaaatctt tcctattata gcatgaaagt ctaaaaaggt
    42301 aaatgattcc taatcatcca gatcaatccc tttttccttt aaattagtca ggcattcctg
    42361 taaataggcc tcttgatgct caggataaat cggtgaggtc agtgccacct cctctaagtc
    42421 ctcataggcg gcaaggcttt ttcctcggta atttttatcc tgccagctca catctggctg
    42481 gtagccccgc gcctgcattt cctgcataat caacaggtga tactggtaaa gcttataaag
    42541 agaatgggca aacacatagt caaccgtcgc atgtggtctc ccccagcctg ctcctcgcaa
    42601 ggccgcacat tcacgatgct gccccaacaa ttgctgcctt ggtaggcgtg tgattaaatc
    42661 ctgatgccaa agacgcataa gctctcctat ttctcttcac tagtcattaa atactgataa
    42721 atctcctgcg gactgcccaa ggccataagc tcttgaaact ttaccagctc ttttagctgt
    42781 tggtaaatga cactgtcagc gatgctacgt tttggggcat cagtctttac cctcatcagc
    42841 ccatcttcga ttactacaaa gcctaactcc tcaaaaattt gtatcatttt gaccaagagg
    42901 attttttcaa tcttgaggta atcacttagc aaggtcagct tatggcgaag atcaaattct
    42961 gggtattgat agatggtctt ataaagcttg gcaaattgct ctctactgcc atagcctgtt
    43021 aggtaataag ggcgcttaat atgattttta aagtaaatcg cttcaaattc ccgatgtcta
    43081 aaaaggcctt tcaaggcatc aatatcgtca ggaacctcat ctatgacaac aaccttggcc
    43141 tgctggtcct caacagctgt aggaatatgc tcaggtgccc tagcagtcct tgctcgaata
    43201 tcaaacagct gcaccccagt cactctagcg tcaaccagca ttaattgcag gctagtatga
    43261 cctcgccagt gattgatcgc aagactaacc gctaattcca agccctgtga ttgctggtac
    43321 tcctgtatca gatgtccctg accaaaggcc aagacatcag cctcaacggc tcctttgctg
    43381 accttgaact tcaagtgact ttgttgctga ccaatggtcc ttgcctgctt aatcgtaaaa
    43441 tcttttaagt aaaaaacagg ctttttatta tccatgccaa agggtgctag aagtagcagc
    43501 ttgttcagac tatctatact caatgcttct aaatccaatt caccattgat caatagagtg
    43561 tttttttcct gaccatcgtg tcccttggct gccacgtatt ggcaaagtag ctctgatagc
    43621 tcctctaggc gatcagatgg cagagtcatg cctgctgccc cctcatgacc accaaaggct
    43681 gtaaataagc tcctattgct attaagtgct tcaaagatat taatgctctc taagcttctg
    43741 gctgagccct tggctagccc ctcatcaatg gtcaaaacaa gaacagtctg cccaatctcc
    43801 tccatgatcc gaccagctac aatccctaag acccctgggt gccagccaga cttagctaaa
    43861 acctgcacag gcttgtctag atcaagcata gccattgctt gagcaaaaat ctcctgtacc
    43921 aagacctttc tttcctcatt tttactacta atcatcaagg caagctcatg aagctcttcg
    43981 tcatcaaagc ctgtcagtag atcaatagct ggatttggat cgtcaagacg ccctagagca
    44041 ttgagctgcg gagcaagctt aaagctaata acatcttcat caaaatgcgc taagtcaacc
    44101 tctgaaagct tcatcagctc ctgcaagcct agtctttctg tctcttttag aacagccagc
    44161 ccgtttttga caaggatacg gttttcacct cgtaggctga ccatatcagc aattgtccca
    44221 atagcaacca gatctaaaaa gtctactgga attgtctcta acagagctga agccaacttg
    44281 aaggcgacgc cacagccagc tagtttttga aagggataag cagcagctgg gtgctcaggg
    44341 tgaataatag caaaggcatc aggtagctct gctggcaggc tgtggtggtc tgttacaata
    44401 acatctaccc cctgtgcttg cgcaaaggca accgcttcat ggcctgaaac accattgtca
    44461 acggtaataa tcagcgaaac ctgctcttgc tcgatgaaat acttgtaaac actttgattg
    44521 ggaccatagc catctgtaaa gcgattaggc aaataaacaa gaggctctgc tcccatcatt
    44581 tccagcgttt ccttgacaat agacgccgct gtcatgccat ctgcatcata atctccgtag
    44641 accaaaatcc tctcaagccc ctcaatggcc tgacgaatgc gatgaacagc tttttccata
    44701 tcatttagca aataagggtc atggagctgt gataggtcag ctgtcaaaaa gctggtaagc
    44761 tcctcttcgg tatgaacacc tcggtcatag atgagctttg cagctgtctg actaagtccc
    44821 tttgcctgag ctagcttaaa gaagccagca tctggctcct tatcagctat ggtccactga
    44881 tatttggacg taatcattta taattaaata cctttcttgc aagataatca gatatagttg
    44941 gaaacaaggt ataacactta tgagcaaggg ctaggctaat aggcagatta atctctcgtt
    45001 tcttttttcc tattgcagca atgatttttt tcgccacagt atccgcctgc agcgtaaagc
    45061 ctgcaacact ggctaaatac tgcccgcttg ggtcagcctg ctcaaaaaag gaggttgcaa
    45121 tcgggcctgg attaacagtt gtcacataaa cctgcctttc tgccagctcc aagcgaaggg
    45181 cattagaaaa gccaatgact gcaaactttg tcgcagaata gatacttgac ttggcagaag
    45241 ctattaagcc tgccattgag acaatattca taatatgtcc agagccctgc tctgccattt
    45301 tgtggccaag caagcgtgca aaatgaatgc tggctaagct attcacacga aacatggcct
    45361 caatctcttc tgcagagaaa tcatcaaagg ccttaaaagc accaaagcct gcattgttaa
    45421 tcaaaacatc aatcctgcca tggcgctggt aaagctcatc aacaagagcc tcaatagcag
    45481 cagggtcttg aatagcaatc tcgtagcatt ccttattacc gcgagcctga tatagactgt
    45541 ctaacctgtc tttgctgcgc cctaacaaaa tcaggtaatc ttctcttgga agctgtctga
    45601 tgatagcctg tgcgagcccg ccagaagcac ctgttatcag aataattctc tgtgccatta
    45661 aatgatcact tcctctaaat cgcgaacaac cttcacattt tcaaaaatag ttgccgcatc
    45721 cttttccatt tgacgacagt cacgtcctaa aaagcgtgct gaaacatgat tcagtaaaag
    45781 acgcttagca cctgcatcac gcgcgatttg agcagcctgc atgtttgtcg aatgcccatg
    45841 attacgggcc attctttcat cacccttccc gtaggtggac tcatgcacca gcacatcagc
    45901 atcttttgcc aatctaacac tagcagatgt cttgcgtgta tcgccaataa tggtgatgat
    45961 ctttcctttt cgaggctctg aaataaagtc cttggcaaaa attttggtgc catcctctag
    46021 ctcaatatcc tgcccatttt taaccttgcc aaaaagtgga ccaaagggca ctcctactgc
    46081 tctaagagct tctgcatcaa gtgttccttc taaatccttt tgaaccacac gataccccat
    46141 acaaaagatg gtatgtgcca agcgctcagc ataaacaata aatttatctg tttctaaaat
    46201 cttgcccata gaggtgtcat caaactcatg ataatgaatc tgataaggca atttagagcc
    46261 tgatatcctg atgctgtttg ttacatagga ttttatccca acaggtccat aaatctcaag
    46321 gtccgtctgc tcctcactag cttgaaaagc ccgactagat aaaaagccag gcaagccaaa
    46381 aatatgatca ccatgcagat gcgtgataaa aatcttcttg atttttcgtg gcttgattgt
    46441 tgtttctaaa atttgccgct gggttccctc gccacaatca aacatccaca cctcattgat
    46501 ttcatctaat agctttagca ctaagcttga aacgttgcga tgcttggctg gctgcccagc
    46561 tccagtacct aaaaattgta attccataca gtctattctt tctaatgcac aaggtaaatc
    46621 atgaattctc tttgtgcaaa ctgataatat ttctttcctt tgaatgcttg gctaagagcc
    46681 aacaattcat cactattaaa gccctttagc agggtcattt cgtttgagaa acgatagatc
    46741 gtggttaaca aagcatgctc aggtgttatg tcctctggct ctccttgctc aaattggcag
    46801 ctcttcatct tgattctacc atcttccaca taaaccacgt attgtggaaa aatctgagcc
    46861 agctccagca gcagcgattc ctcaggctgc ccctgctctt tttcagcaaa aacaatcgcc
    46921 tcctgtgctt cattttcaaa gacaaagcca taggattgcc ccaacaaatt taagcggaca
    46981 aagggcttca cctcatcaaa tgacggctct gaggtaaaca gcttcaaggc ccttgatagc
    47041 tcaaaataat aatctgtcgc tgcttttggt gattgcttct gatacatttc tgcaaaataa
    47101 gcattaatca cacttggggg tggcgtgatg gtagctaatt tttgctggtc tgtcaagccc
    47161 tttaagcaat tttgcaaata aaccgtatct aaactcgtaa agcctccata agtctttgcc
    47221 aattgaatat aatcagtcat aaaattcttc taatctccat ttatttttgg gagcaatgta
    47281 gccagaaatc tcttcaatct ccttatcaaa gctataaggc tccaataacg ccaacctgtt
    47341 gaggtcatag catttgtagg cttgatcctg acagagcttg atcgaaaatg gctcaaacat
    47401 gtcccgaatc tgatcaataa gcaactgtct taagaggcta cgactgtttt tatcacgtgc
    47461 tgacagcctg acatttggaa aaacagttgc agtcaagcta gctgtcttat ccatcttgtt
    47521 ataaatagcc agccttggaa tatccagcat atctaaatct ttcaagatgt ctagaacaac
    47581 cctctcatgc tccaaatgat tagggtcact ggcatcaatc acatgcaaga gcaaatcaac
    47641 atgccgactt tcctctaatg tcgacttaaa agcagccacg agctccgttg gtaaatcttg
    47701 gataaagcct acagtatctg tcagagttgc ctgaaactga ttttgcagat aaatttgctt
    47761 ggtggtggca tcaagtgttg caaataattc atcagcctca tattgcttgt caccagtcaa
    47821 aatagtcata atagtagact tacctgcatt ggtatagccg atcaatccaa tattaaagac
    47881 atcagaggtc atgcggcgat cacgaatcgt ttgacggttt ttttcgacag cagctagctg
    47941 ccgctcaata tctgcaatct gatgacgaat ggagcgccgg ttcagctcca gctggctctc
    48001 acccggccca cgactcccaa tgcccccggc ctgacgacta agcataacac cctgtccgac
    48061 cagtcttggc agcatgtatt tgagctgcgc taaatgcacc tgcaattttc cttcatggct
    48121 tctagcccgc atcgcaaaaa tatcaagaat cagctgcatg cgatcaatga ccttaatacc
    48181 taaggcgtcc tccaaattgg cattttgccg agccgttaaa cgattgttaa caatcactgt
    48241 atcaatctca ttggcagcaa ccatttcttt gatttcagcc agcttaccag agccaacaaa
    48301 ggtcttgcta tcatagcgct ccctcttttg cagatagcaa tcaacgacct ctgcacctgc
    48361 ggtcttggct agactagcca gctctgtcat tgatagctca gcatggtcag ctgcttgtag
    48421 gaccacgctt agtaaaataa ctctttcctg ccttgccttt gtctctatca tgaacgcgac
    48481 taatcctcca aattccgtag tgtttattat agcatagttt tagctatttt cagctagttt
    48541 gccatcgata gcttcctaag gctccttcaa aaagcgctcc accctatcat atattgcctg
    48601 cggataggac gactcgctaa tcgagtcaaa gcgcactgcc atacggttac gaaaccaagt
    48661 cagctgtcgt ttagcaaagc ggcgtgtttg ctgctttagt gtggctgttg cttcttctaa
    48721 actagcctga ccctgaaagt aagggaagag ctccttataa ccgatccctc gactagcctg
    48781 aacagctgga tactgctcaa aaagccacct tgcctcctcc aataggccag aagccatcat
    48841 cagatccacc cgcttattaa tccgctcata aataacctct cgctcatcag tcaagccaat
    48901 gatcaagggg ttataggggg cctcttgatt ttctaaatcc ctagcaaatt gatttagctc
    48961 aagtgagcga atggcacgcc tgcggttaac ctgatcaagg tgaatgccct tactagctaa
    49021 tagctgataa agctctgtat ctgtcagtgt ctctagctgc tgccgataag caagtagctc
    49081 cttttgatca agatctcctc ctagatgata gccctctaac aggctttgca aatacaggcc
    49141 ggtaccaccg acaataatcg gcagtttacc gcggctaaca atatcttcaa tagctcgctt
    49201 agcgtcctgc acaaaatcaa aggctgagta agactctgtc acctcacgaa tgtcaatcaa
    49261 atgatgaacc gcaagagcct gctccctggc actagcctta gctgtcccaa tatcaaggtg
    49321 acgataaacc tgctgactat ctccagatat aatttcacca ttaaaggcac cagccaaggc
    49381 aatccctaga gctgtcttgc caacagcagt cgggcctaca atcacaatta tcttttcttt
    49441 tgtcatttat tgtctttcta cttaaaaagc agctgaaaaa gtcttttact tgaattttct
    49501 aatctttttc gctaccatat attataacat aagattgaga gacagttatg gtcctcttaa
    49561 tagaaatgga gaatgattat ggctaaaaaa catggattcg caaagggtct tgctacaggt
    49621 gttcttgcta ctgctgctac cgttgcaggt gcagtatttg ctgttaaaaa gactattatt
    49681 gaccctgagg aagaaaaagc agcatttgta gaggaaaatc gtaaaaaagc agcacgtcgt
    49741 cgtgttgctc gctaatcact aatagatgaa agattcgaca ggctttatca atagcctgtc
    49801 gaatttttta tgctgtgaga ccaagctttt tgcttagaca cataaaagaa acagctcgtc
    49861 agcgccgcat actgcctact tcattgacca acaaacaggg caaactaagg ctaattttca
    49921 ctgatatgac atgtttcgac tataaagcgg ttttgtgatt gattgatcac aatatcaaat
    49981 tgctggtgat aagggtgcag ataacgagca tattgagcgc gcctattgac atgatgaact
    50041 ccggattgcg acctctaatg ctagtatctc taccaagccg cctttggagc tctgtgtcac
    50101 catctgtata aaagtaaagc gataagtcaa acaactctgg ctctaaaaag gttgtcgaca
    50161 tgccttcagc aataaggatg ggcacattcc ccttcaccaa aaaagaggga gaccaagggg
    50221 tatcaatact caaaaaatcc agtccttgct taaacatcat gatgtcacgc ctcagactgg
    50281 ccaattcgtg cctagcaggg tgacaggctg ttatactacc aagtacctcc tctccctgat
    50341 cagggtagct aatcaaaaca gcctgactaa aatcattagc gatgatatag gcatctgttt
    50401 ctaacaattg gctttgtcca tcaggcaaaa gctgctgtaa gcgcttagca aaggttgatt
    50461 taccagatgc accatgacca ctaattctaa taagcatttt ctcacgattg gctgctgcag
    50521 ttacaatagc ttgaagtagc ttctccatta tctctcctca tcaaataaca ttctaataat
    50581 aggacatcat tctacatcga aaaacaagcc ggtctcccga aacagcctga ctgacagtaa
    50641 aaaaagattg aagggcaatc caataaggaa agcttctcca atctgattaa tagtctataa
    50701 tggcttaata tgagtgccaa atgtcttggt tatattgttc aatcgtacgg tccgatgaaa
    50761 agaagccagc cttagcaata ttatgcacaa cctttgtcag ccataggtcc tgattgtcat
    50821 aatcagccag catttgttct ttgactgcaa tgtattcctc aaggtcaatc aaggtcataa
    50881 accagtcctt agagattaac tccttataga gacggtcaag acgttcctca ttaccaagct
    50941 ctaataattc tggactgata ataaagttaa ctgcttcctt gatagctggg tgggcatcat
    51001 aatagtcttt agacacataa ccacctgtgg cataaagatc aataatggta tctgaatcct
    51061 taccaaaggt gtagatatta tccataccag caagctcagc gatttccaca ttagccccgt
    51121 ccatagtacc aagcgtcaag gcaccattga gcatgaattt catattacca gtacctgaag
    51181 cttcctttga agctagagaa atttgctctg aaatatcagt tgcaggaatc aaatgctctg
    51241 ctactgtcac attgtaattt tcaacaaggt gaacattaag gtatggactt acctccggat
    51301 cgttattgat aagctctgac aagcaaagaa tcaaatgaat aatatcctgt gcaatgatat
    51361 aagccggtgc agccttacca ccaaagataa ctgttatttt acgcttcggc aggttgcctt
    51421 ttttgatctc taagtattta tgaatcacat aaagggcatt catctgctgg cgcttatatt
    51481 cgtggaagcg tttaatttgg gtatcaatga ttgaatgctc atcaagctca attcccttat
    51541 tatccttgag gtagcgcttt aaggctactt tattatggtg cttaatttca gccaatcttg
    51601 catgaacagc ttgatcctca gcaaaggcca ttaatttttc aagccttgtc gcatcagtca
    51661 agtaagcatc accgataagc tctttaatat agtccgccaa ctcttggttg gcgaattcta
    51721 gccaacgacg gaaggtaata ccattggttt tgttgttgaa tttttctgga tacagctcat
    51781 agaaggcctt caattcgcta tttttcagga tttcagtgtg aagggcagca acgccgttga
    51841 cacttgtggc aaaatgaata tccatatgtg ccatatgcac gcgacctgtt tcatcaatga
    51901 tttggacagc tggatctgat acccttgcac gaacaagagc atctaattgc tcgataatcg
    51961 ttaccagctg cggcacaacc tcattaagga agtcaagagg ccatttttcc aaggcttctg
    52021 caaggatcgt gtgattggtg taaccatcca tcttttgaac cactgaaaca gcctcatcaa
    52081 aatcaaagcc atgcttttgt gtcaatagac gaatcaattc tggaatgacc attgatggat
    52141 gggtatcatt gatctgcacg tatgcgtaat cagctaagtc atgcaggttt gagccacgct
    52201 caagcgcttc atcgatcaag agctgagcgg cattagatac catgaaatat tgctggtaaa
    52261 tgcgaaggag ctcaccattt ttatcagaat catcagggta aaggaacagg gtcaggtttt
    52321 tggcaatgtc agtcttatca aatgaaatgc catctttaat caagccataa tcaacccctt
    52381 caatatcaaa aaggttaaga tagttcttgg tgtcacgctt atagcccaaa acatcaatac
    52441 ggtctaagcg agatttcagg gtaaagtttt taaagggaac atcatatgaa atgtcagtcg
    52501 gtactagcca agagtcatcc tctatccaaa aattaggctc tgctgtttgt tcattgtgtc
    52561 taaagacctg cttgaacaag ccacaatgat aattcaagcc aaccccttca ccattaatgc
    52621 caaggcttga gatagaatca ataaagcaag aagccaaacg accaagacca ccattaccaa
    52681 gcgatggctc caattcaacg tcctctacct cagcaattga tttgcccgca gcagccagct
    52741 cctctttgat gtccttataa atacctagat taatgagatt attagaaagc aacttaccaa
    52801 tcaaaaattc tgctgagatg taataaacct tacgtttagc tgtgtttttt gcttttttgc
    52861 ttgcttcttc tttgagatag gaaagcaacg aaagatagat ttcctcgttg cttgcacttg
    52921 caagagattt tcctaatgtc atttcagtat aatctgtaaa gcgtttcatg atatcctctt
    52981 ttcaatatag tattctagtg atgattattg gctcgaccgt atagctcagt caaatggatt
    53041 aaataggcct tgtgctctgc tttaatatcg tcctcaagca tgcgccactg ccagttgcca
    53101 ccgacagtgt ttggcatatt catgcggcta tcagctgact tatccagcaa atcctgcata
    53161 cacaggatag cagtatcaca cacagtcgca aagattgttc ttagcatggc cttggtgatg
    53221 ctttcagcag ctgccttatg gatataatga ttaacaaact caacctgctc tgcgctcaag
    53281 tgctcatacc agccattcac cacctcattg tcatgcgtac cagtgtagac aatgcaattg
    53341 tgatcatagt tatgcggcaa atcaaagctt tgacttgtca catcaaacaa accaaactct
    53401 aaaatcttca tgcccggaaa gccagtagat gccagcagct gctcagcctt ttcatcaatg
    53461 tagccaaggt tttctgcgat aattggcagc tcacccaagg cctctcgaac agctttaaat
    53521 agagcaatac caggagctga ctcccaatga ccatttttag cagtcacatc accaccagga
    53581 atttcccaaa aatctgagaa gcccttgaaa tggtcaattc taagcttatc gtacagcttg
    53641 aagctctctt tgatccgatg gatccaccaa gcaaagcctg tttgctcatg gctctcccag
    53701 ttgtaaatag gattgcccca aagctgcccg tcctcactaa agccatcagc aggtacacct
    53761 gcaatgtaaa tcggcttttt atctgcatcc accttaaaga gctctggcat cgtccaaacc
    53821 tcaacgctat cagcagacac gtagattggc atatcaccaa tgatagtaat gccattttga
    53881 ttagcatagg tcttcagcgc tagccactgc tgataaaaga aatattggca gaccttatga
    53941 taggtgatgc ctttggccaa cagcttgcgg taatgaagca aggcagcctc ttcacgctta
    54001 acaattgctc tatcgtccca ttcctggagg gccttgtgat caaaatgctc tttaatagcc
    54061 ataaattcag caaaatcatt tagccagctc gcagttgctt caaattcggc gagctgtctt
    54121 aagccttcct cagttgagac aaaagcctga actgcttttt ctaataaagg gcgtctggct
    54181 tgaaagactt gagcgtaatc aacagactcc ggatttgagc caaaatcaac agcagcataa
    54241 tcagcttcct gcaaataacc gtcctttgcc agcaattcaa ggtcaataaa atgcgtattt
    54301 cctgcaatag ctgaaaaaga ttgataagga gaatctccaa agctagttgt tgttaagggc
    54361 aaaatctgcc aataggtctg cttggtttcc tttaaaaagt caacaaattc aaaggcctct
    54421 ttaccaaagc tcccaatacc gaagcgtccc ggaagcgagc tgatatgcat cagaatacca
    54481 cttgcacgtt tagtcattct ttttttctcc ttgtaaaatc ttaatgttga aattataacg
    54541 caaccgtttg cgcaagtcaa tatcttttca aaaaaaaaga gactttttcg gcatgctaga
    54601 gctgctcaag ccttgataat aatgagggaa gcagctagga caaaaacaaa aaaaggattg
    54661 gagagacagc ctaagcagct gctcttccat cctcatctca ctcctatttg gcattaatat
    54721 ccctgacact ctctcgcttt ttgaggctaa agggaaccaa aattttctga ctcagggttt
    54781 gttcattggc attgataatg tctaagagct gcctaaagga ggttcttccc aaattttcaa
    54841 cgttaatatc aaatgttgtt aagtaagggt gaatcaattt cgaatagcta gaattattaa
    54901 aggtaataat cgaaatatca tctggcacct taatgtcata aaaggacaag agctggacca
    54961 ttcgcaccga caaaacatca ccaatcacga ttaaggctgt ggccttaaag ctacgtatcg
    55021 tttcaataac cttttcgatg cttattggat cctttcgatc aaataacagc atcggtttgt
    55081 tttccaagga taatttcaag cagcccttga gatagccaat atagcgctca gaagctacct
    55141 ctgcctccat atcgtctgtg ataaacagga tctgtcggtg acccttttga tagagatgat
    55201 caactgcggt tttagccatt agctggttgt cattgtcaat ataggtgatt ttgttctcat
    55261 caccttctgg tgcgccaaca atgacaaaag gaatctggtt ggtcatcaaa tagcctctaa
    55321 caggatcttc ttgctcagaa tataatataa taaagccatc aacacgcttt tgcaggtgca
    55381 ttaacttaac ctggctcaat aaatcctcaa cagacatacc tgttgcaatg gaaacagtga
    55441 aatgatgttt cttagcttca ttggtaatgg tcgatagaat ttccataaaa aagggatcac
    55501 tcaaacgatc attagtgata atcggcggaa aaaccaggcc aatattatgt gtcaggccac
    55561 tagcaagcat ttgcgcagct acattcggaa catagccaag ctcgctcata gctcttctaa
    55621 ccttttcctt tgtcttttgg gagatagatc gattatcctt gaggacacga ctgacggtcg
    55681 aaggattaac acctgctttt aaggcaacgt cttttattgt aaccatataa acctcattta
    55741 atacctgata atgacgctat gtcaggcttt ttcacatgta ttttgctttt attatacaat
    55801 tatctcctaa aaaatcaact ctcgccctgc aagaaggcga cataaaaaac tgctgtcctc
    55861 atgatcgaaa aaatgttaaa aaaatcaact ttttttaaaa aaagactaga ctttttctgt
    55921 aaacggttgc ataatattaa gtgtaagaaa tatatcttag gaggaaatcg ctatgaaatc
    55981 atggcaaaaa gttatcgtca gtggggcaag cttgacactt gctagcgcct tattagtagg
    56041 gtgtgcatct ggttcaaagg acaaaacaga aactgcatca ggtactgatt caaaaacaat
    56101 taagctttgg gtaccaacag gagctaaaaa gtcatacaca gatgttgtcg ctaaatttga
    56161 aaaggactct ggctacaagg ttaaggtgat cgagtcagag gatccaaaag cacaagaaaa
    56221 aatcaaaaaa gatgcttcta ctgctgccga tgtcttttca cttcctcatg accagcttgg
    56281 tcagctcgta gaatctggca ttatccaaga agtcccagag gaatacacta aagagatcgc
    56341 tgatacagca actgatcaag ctatccttgg tgctcaatac aagggtaaaa cctatgcctt
    56401 cccatttggt attgagtcac aggttctctt ctacaacaaa actaagctag ctgctgatga
    56461 tgttgcttca tacgatacca tcacgtctaa ggctaccttc ggtggtacct tcaagcaggc
    56521 taatgcttat gctactggtc cattgttcat gtctgttggt aacacattat ttggtgaaag
    56581 cggtgaagac actaaaggaa ctaactgggg caatgaaaaa ggggttgctg ttcttaaatg
    56641 gatttcagac caagcctcaa acaaaggatt tgttaactta gatgccaaca acgtcatgtc
    56701 tcagtttgga gacggttcag ttgcttcatt tgaatcaggt ccttgggatt acgaggcagc
    56761 acaaaaggct atcggtaaag aaaaccttgg tgttgctgtt tatccaaagg taactatcgg
    56821 tggcgaaacc gttcaacaaa aggccttctt gggagtgaag ctctatgcgg ttaaccaagc
    56881 tcctgctaag ggagatacca agcgtatcgc agccagctac aagcttgctt catacctaac
    56941 aaatgctgaa agccaagaaa accaattcaa gacacgtaac atcgtaccag ctaacaagac
    57001 cgttcaagct tcagaggctg ttcaatcaaa cgagcttgca aaaacagtta tcacaatggg
    57061 atcttcttca gattatactg ttgttatgcc taagcttagt caaatgggta ccttctggac
    57121 tgaaagtgct gcaatcctta gcgatgcctt caatggtaaa atcaaagaag gtgactacct
    57181 tgctaagcta cagcagtttg acaaggacat tgcagcaaca aaataagcta tctcatttat
    57241 aatactatcc taaacaagta cagaggtggg ctattttaac gctatccttt ctactcatct
    57301 ctaaaggggt ggaactaagc atcattattt tttcagggct tagtccactc ctacttgttt
    57361 ttgatatgac gtaaagcttg gtgctactta aatttttaat cgcttaaaga tttaggtaac
    57421 acttagctat gtggtcgtta gcaccaaacg cttatgacca cagcatctga acaagagagt
    57481 caggtaatcc tactttcttg tatcctaaca taaaggagaa catatatgac tcaggcaggc
    57541 ttagcatctc aggttactgt aaaagaggct ttaacaaagg gaagcttcga tattaaacta
    57601 tccgctatca tcatgggctt tgccaatttt gctaataaac aattcgtcaa aggaacactc
    57661 tttttattga gtgaggtggt ctttttcatc gcctttgttt cacaaatcat tcctgctatt
    57721 ggcggcctca ttaccctagg aacacaaaca cagggcatga caaccaaaac tatcgacggt
    57781 atcagcattc aggttgctgt tgatggagac aattcgatgc taatgctgat ttttggctta
    57841 gcctctctga ttttttgttt gttatttgcc tatatttatt ggtgtaacct aaaaagcgcc
    57901 cgtcacctct acatgctaaa gcaagaaggg gcaaaaatcc caagctttaa ggaggatttt
    57961 gttagtctag caaatggtcg tttccatatg accttgatga caattccatt gattggtgtg
    58021 cttctgttta cggtacttcc tttgatctac atgatttgct tagcatttac taactttgat
    58081 cacaatcacc tcccgccaaa gtcacttttt gattgggttg gtctttccaa ttttggtaac
    58141 gtgttaagtg gtcgtatggc aggaaccttc tttcctgttt tctcatggac actgatttgg
    58201 gctgtctttg ccacagtgac taacttcttc tttggtatca ttttagcact cttgattaat
    58261 accaaaggct taaaattgaa aaaaatgtgg cggaccttct ttgtgattac catcgcagtt
    58321 cctcagttta tttcactgct gattatgcga aatctgctaa atgaccaagg tcccttaaat
    58381 gccctgctta gcaaattagg gttaatccac cattctctac cgtttttatc tgatccaatt
    58441 tgggctaaat tctctattat ttttgttaat atgtggatcg gtattccatt taccatgtta
    58501 atcgcaacag gtatcattat gaacctgcca agcgaacaaa ttgaggctgc agagattgat
    58561 ggggcaagta aattccaggt cttcaaatca atcaccttcc ctcaaatcct cattatcatg
    58621 acaccaaacc tgattcagca atttattgga aacatcaata acttcaatgt gatctatctc
    58681 ttaactggtg gtgggccaac caattcagcc tattaccaag ctggaaccac cgatctattg
    58741 gtgacttggc tctataaatt gactgttaca gcagcagatt ataatctagc ctctgttatt
    58801 ggtatcttaa tctttaccgt atcagcaatc tttagcttac tggcttacac aagaactgca
    58861 tcatacaagg aaggagcagc gaaataatga aaaacaaacg tcgatttcag cttggattag
    58921 tttacgccat tttaaccgtt ctctcaatca tttggctttt acctatcgct tgggttgttc
    58981 tgactagctt tcgtgctgaa ggcactgctt atgtcgatta ttttcttccc aagcacctca
    59041 cattagacca ttatattaag ctctttacaa atgaaacatt tccttttggg agatggtttg
    59101 tcaatacctt tgttgttgct atctttacct gtatcatctc aacctttatt acagtggcga
    59161 tggcttactc gcttagtcgg atcaaattca agtttcgcaa tcgtttctta aagcttgcac
    59221 tagtgctaaa catgtttcca ggctttatga gcatgattgc tatctactat atcctaaaag
    59281 cacttggcct tacgcaaagt cttaccgccc tagtccttgt ttattctgcc ggtgctgcac
    59341 ttggatttta cattgctaag ggcttctttg ataccattcc ttattcgctt gacgaatctg
    59401 ccatgattga tggggctact cgtatggata ttttctttaa gattacccta ccgctatcaa
    59461 agccaatcat tgtttacact gcactccttg cctttatggg accttgggtt gactttatct
    59521 ttgcccaagt gattttagga gatgcaacca gcagatatac ggtagctatc ggactctttt
    59581 caatgctgca gcctgacacc atcaatgact ggttcatggc ctttaccgct ggatctgtgt
    59641 taattgctat tccaatcaca ttgctcttta tgtttatgca aaaatactat gtagagggcg
    59701 ttacaggtgg ttctgtcaaa tagcagtaat gatcacgata acccttactc aaaaaatcct
    59761 tccc
//
LOCUS       DARYLJ010000005        58406 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYLJ010000005 DARYLJ010000000
VERSION     DARYLJ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58406
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..600)
                     /locus_tag="TU746_000257"
     CDS             complement(<1..600)
                     /locus_tag="TU746_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0890645.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
     gene            1005..1649
                     /locus_tag="TU746_000258"
     CDS             1005..1649
                     /locus_tag="TU746_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890646.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1654..2403
                     /locus_tag="TU746_000259"
     CDS             1654..2403
                     /locus_tag="TU746_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL0890647.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TU746_000260"
     CDS             complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TU746_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0890648.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TU746_000261"
     CDS             complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TU746_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL0890649.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            3125..3955
                     /locus_tag="TU746_000262"
     CDS             3125..3955
                     /locus_tag="TU746_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890650.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4015..5295
                     /locus_tag="TU746_000263"
     CDS             4015..5295
                     /locus_tag="TU746_000263"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL0890651.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5500..6792)
                     /locus_tag="TU746_000264"
     CDS             complement(5500..6792)
                     /locus_tag="TU746_000264"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0890652.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6782..7498)
                     /locus_tag="TU746_000265"
     CDS             complement(6782..7498)
                     /locus_tag="TU746_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0890653.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7752..7976
                     /locus_tag="TU746_000266"
     CDS             7752..7976
                     /locus_tag="TU746_000266"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890654.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7987..8907
                     /locus_tag="TU746_000267"
     CDS             7987..8907
                     /locus_tag="TU746_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890655.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8894..9634
                     /locus_tag="TU746_000268"
     CDS             8894..9634
                     /locus_tag="TU746_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890656.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9791..11539
                     /gene="aspS"
                     /locus_tag="TU746_000269"
     CDS             9791..11539
                     /gene="aspS"
                     /locus_tag="TU746_000269"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL0890657.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11532..12479
                     /locus_tag="TU746_000270"
     CDS             11532..12479
                     /locus_tag="TU746_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0890658.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12495..13376
                     /locus_tag="TU746_000271"
     CDS             12495..13376
                     /locus_tag="TU746_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0890659.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13520..14434
                     /locus_tag="TU746_000272"
     CDS             13520..14434
                     /locus_tag="TU746_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0890660.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14606..16000
                     /locus_tag="TU746_000273"
     CDS             14606..16000
                     /locus_tag="TU746_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0890661.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(16048..17739)
                     /locus_tag="TU746_000274"
     CDS             complement(16048..17739)
                     /locus_tag="TU746_000274"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL0890662.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            18016..18453
                     /gene="argR"
                     /locus_tag="TU746_000275"
     CDS             18016..18453
                     /gene="argR"
                     /locus_tag="TU746_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0890663.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18455..18805
                     /locus_tag="TU746_000276"
     CDS             18455..18805
                     /locus_tag="TU746_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL0890664.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18792..21347
                     /gene="mutS"
                     /locus_tag="TU746_000277"
     CDS             18792..21347
                     /gene="mutS"
                     /locus_tag="TU746_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL0890665.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21494..23476
                     /gene="mutL"
                     /locus_tag="TU746_000278"
     CDS             21494..23476
                     /gene="mutL"
                     /locus_tag="TU746_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL0890666.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23487..24710
                     /locus_tag="TU746_000279"
     CDS             23487..24710
                     /locus_tag="TU746_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0890667.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24712..25308
                     /gene="ruvA"
                     /locus_tag="TU746_000280"
     CDS             24712..25308
                     /gene="ruvA"
                     /locus_tag="TU746_000280"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL0890668.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            25318..25869
                     /locus_tag="TU746_000281"
     CDS             25318..25869
                     /locus_tag="TU746_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL0890669.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(26305..27150)
                     /locus_tag="TU746_000282"
     CDS             complement(26305..27150)
                     /locus_tag="TU746_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0890670.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            27447..28019
                     /locus_tag="TU746_000283"
     CDS             27447..28019
                     /locus_tag="TU746_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL0890671.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            28013..28303
                     /locus_tag="TU746_000284"
     CDS             28013..28303
                     /locus_tag="TU746_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890672.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
     gene            28989..30260
                     /locus_tag="TU746_000285"
     CDS             28989..30260
                     /locus_tag="TU746_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL0890673.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            30354..31490
                     /gene="recA"
                     /locus_tag="TU746_000286"
     CDS             30354..31490
                     /gene="recA"
                     /locus_tag="TU746_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL0890674.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            31866..32264
                     /gene="spx"
                     /locus_tag="TU746_000287"
     CDS             31866..32264
                     /gene="spx"
                     /locus_tag="TU746_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL0890675.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            32377..32646
                     /locus_tag="TU746_000288"
     CDS             32377..32646
                     /locus_tag="TU746_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL0890676.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            32643..33062
                     /gene="ruvX"
                     /locus_tag="TU746_000289"
     CDS             32643..33062
                     /gene="ruvX"
                     /locus_tag="TU746_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL0890677.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            33072..33371
                     /locus_tag="TU746_000290"
     CDS             33072..33371
                     /locus_tag="TU746_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL0890678.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            33919..35478
                     /locus_tag="TU746_000291"
     CDS             33919..35478
                     /locus_tag="TU746_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL0890679.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            35575..37773
                     /gene="nrdD"
                     /locus_tag="TU746_000292"
     CDS             35575..37773
                     /gene="nrdD"
                     /locus_tag="TU746_000292"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL0890680.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            37879..38025
                     /locus_tag="TU746_000293"
     CDS             37879..38025
                     /locus_tag="TU746_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890681.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            38053..38988
                     /locus_tag="TU746_000294"
     CDS             38053..38988
                     /locus_tag="TU746_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL0890682.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            39001..39495
                     /locus_tag="TU746_000295"
     CDS             39001..39495
                     /locus_tag="TU746_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0890683.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            39505..40119
                     /gene="nrdG"
                     /locus_tag="TU746_000296"
     CDS             39505..40119
                     /gene="nrdG"
                     /locus_tag="TU746_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL0890684.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(40577..41308)
                     /gene="yaaA"
                     /locus_tag="TU746_000297"
     CDS             complement(40577..41308)
                     /gene="yaaA"
                     /locus_tag="TU746_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL0890685.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            41756..41959
                     /locus_tag="TU746_000298"
     CDS             41756..41959
                     /locus_tag="TU746_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0890686.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            41961..42414
                     /locus_tag="TU746_000299"
                     /pseudo
     CDS             41961..42414
                     /locus_tag="TU746_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            42424..43098
                     /locus_tag="TU746_000300"
     CDS             42424..43098
                     /locus_tag="TU746_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL0890687.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            43128..43565
                     /locus_tag="TU746_000301"
     CDS             43128..43565
                     /locus_tag="TU746_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890688.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(43788..44561)
                     /locus_tag="TU746_000302"
     CDS             complement(43788..44561)
                     /locus_tag="TU746_000302"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL0890689.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(44645..45712)
                     /gene="pepA"
                     /locus_tag="TU746_000303"
     CDS             complement(44645..45712)
                     /gene="pepA"
                     /locus_tag="TU746_000303"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL0890690.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPAHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            46057..46404
                     /locus_tag="TU746_000304"
     CDS             46057..46404
                     /locus_tag="TU746_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL0890691.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            46401..46718
                     /locus_tag="TU746_000305"
     CDS             46401..46718
                     /locus_tag="TU746_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL0890692.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            46733..47359
                     /locus_tag="TU746_000306"
     CDS             46733..47359
                     /locus_tag="TU746_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL0890693.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(47662..48375)
                     /locus_tag="TU746_000307"
     CDS             complement(47662..48375)
                     /locus_tag="TU746_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0890694.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            48487..48882
                     /locus_tag="TU746_000308"
     CDS             48487..48882
                     /locus_tag="TU746_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0890695.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            49329..50303
                     /locus_tag="TU746_000309"
     CDS             49329..50303
                     /locus_tag="TU746_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0890696.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            50321..51283
                     /locus_tag="TU746_000310"
     CDS             50321..51283
                     /locus_tag="TU746_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0890697.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            51398..52282
                     /locus_tag="TU746_000311"
     CDS             51398..52282
                     /locus_tag="TU746_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890698.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICAAGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            52291..53094
                     /locus_tag="TU746_000312"
     CDS             52291..53094
                     /locus_tag="TU746_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0890699.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(53193..54197)
                     /locus_tag="TU746_000313"
     CDS             complement(53193..54197)
                     /locus_tag="TU746_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890700.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(54483..55124)
                     /locus_tag="TU746_000314"
                     /pseudo
     CDS             complement(54483..55124)
                     /locus_tag="TU746_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(55145..56122)
                     /gene="dusB"
                     /locus_tag="TU746_000315"
     CDS             complement(55145..56122)
                     /gene="dusB"
                     /locus_tag="TU746_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL0890701.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(56109..56981)
                     /gene="hslO"
                     /locus_tag="TU746_000316"
     CDS             complement(56109..56981)
                     /gene="hslO"
                     /locus_tag="TU746_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL0890702.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(57231..>58406)
                     /locus_tag="TU746_000317"
     CDS             complement(57231..>58406)
                     /locus_tag="TU746_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL0890703.1"
                     /translation="LHNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNT
                     ELTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELV
                     GYISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLE
                     LENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLS
                     IIYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTN
                     KSVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYIL
                     KEKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT        16833 a        10320 c        13187 g        18066 t
ORIGIN      
        1 ttccgcattc cttttatcag cctctgcttt ttctttatcg gttttagctt gttggtaatc
       61 ttcctcaact tttcgagttt tttgtttttc agtgtctaat aatccctcta gtttatgtaa
      121 attttcaatt gttactttga aagcattcct agttttttct aattcacttt ctgcaatctg
      181 tttctctatt ttagctttag tttctaattt ttgagcttgc tccaaagctg agactctttt
      241 ttttatttca ttaacaactg cctttctatt atcatttttg tttggattgt tgaaatatga
      301 taataatggt gtgattgggc catttaatat aaaactaaaa ctttctggat ctatatttac
      361 atcggctgat ataatagcaa ataaagcaaa caatgtattg ggatcactaa tttgtcctaa
      421 tactgttttt aacttaccac tatctgattg taaaacttgc tcaatttttt ttacgtccgc
      481 actcatatct ccatacacaa ctttatttcc aagtagtcct gttcctatca ggcttcctgt
      541 gatgagagta gctgctaggg cttgatgaca caagcgtctg atgtttgatt gtcttttcat
      601 gatttagtcc tcacatatcg tcgaatgttt tttctaaaat tcttccaaaa aatcttaaca
      661 tgacgcttgc aggctgtgaa tacgttttgg gcaattcgcc tccgtagttt cgtttttttt
      721 aattcaatca ttaaacgtct gattttatca tgatataatt gatcttgttc aaggctgatc
      781 aggaaattct tgatgaagat gacagcttta tatcggtgtt tgggaaacca taagattggc
      841 aaggctacgc tgggcttagc tgacattgtt gcttcaaaat gctttcaggt gtagaaatgt
      901 tgacaagtat tctttaaaaa gatagactat agctagtagg atagaggtat gcacaggtga
      961 cagatgtgat acttgtgttt tttgctattt ttggaggttt ctgattgcct attgcagctt
     1021 atcaatatga aagtgttgtt gagattatta gtgaaatcaa tcgattacac tattcatttt
     1081 cttcgggttt aggagctctt ctatgcttta atttgaaaaa gagtgtcagt tcggtagtcg
     1141 ttaacaatcg tattgatagg gagttccaag agctcatcgt ttcttataaa gcaaggctaa
     1201 ataggaatat tagtcaagtc tcaagcatac gacatcagtt tataggcatt agatggagaa
     1261 taaagcaagc agaatctatt agtgagaagc ttttatacta catgagcgag aatcatgagt
     1321 ttggaaggat tcccttaaat aaatgtttga atgattttct tggatttagg atcttggtca
     1381 ataacttaga agttgttttt gctgctttgc aaaatgataa tcgagtgact aatattgcta
     1441 aattgtattt aagaacagat ggcgactata aaggtatcca tctatatttt aaaaatggaa
     1501 ataatcggtt ttttccatgg gaattacaga tttgggatcc agagcaatca cgcttaaatg
     1561 agctgtcaca taaagagcat aagcaaaaac gacaatatat atcactaccc caacattatt
     1621 ttgatgctaa tttagaaaag gaggaataac cgcatgtatc agcattttat tttagttgct
     1681 agttcatatg caagaggtga gagagttggc tttcacttag cgacagaagg tcaattggat
     1741 catgttgcca ttgaagaaaa aatgcagcgg ctgagtcata tcaatagaga tgatgttggt
     1801 gtgcattctt ttgttacaga tagtgctgat tggcaaagtg tcattgagtt agattccttt
     1861 tttgaggata ttatggtttg tcaagacttc gatgaatttg aacaggtttt acaatccgac
     1921 tctaaaatta gtgctattga tgttgctaaa tttttcttag caatgcgtcc actctcacac
     1981 ttacaattgc aaaagttagt ttatcttgct tataaaacat atcttcttgc ctatggtgaa
     2041 tccttatttg atgaaaaaat agttgctttt caatatggtc ctgtagtaga agaggtgtat
     2101 cacagcttta aaaaatatgg ttctgaggtg atagatatcg atgatcatac agaatatatt
     2161 ttaaaagaca tacatcttcc gcaagcctta ggtagaatgc tattggtcga agacgcaaag
     2221 aagattgtgc ctgtattatt agatgttgtt aaacagtatg gagatttaac aggaggagaa
     2281 ttggttaagc tgacgcactc tgaaaaggga ccttggcaga cggtttttcg tccacagtta
     2341 aattgtgaga tcactgatga ggttatttta gcccaaggca gatatgaaag attatcatca
     2401 taagtacctt tgcttattgt attagctgag aatactcagt tgtctcatca aaaccaaaac
     2461 aaaaaagcct ttgaaacgtt gatttcaagg gctttctgta tatcgtctta ttttacctct
     2521 gtaaacacaa catgtttacg tagttttggt gagtattttt tcaattgaag gcggtctgga
     2581 gtgttacgtt tgttttttga agtaaggtac aagcgttcac cagattcttt gtgttcaagt
     2641 gtgatattta cgcgcatggt atctcccttc tattattcag ctgcgttagc tttagcgatt
     2701 ttatgtcctt tgtagtatcc cttaagtgag acacgatgtg aacgtgagta atctccagtt
     2761 gtttcgtcaa attttactga tggtgcagtc aatttgtagt gtgtacgacg tttgttcttt
     2821 ttagcttttg acgtgtgacg tgcaggaact gccatttttt ctatcctccg ttaaatgatc
     2881 aagggtctat taaaagattg gtgacaaact ggtgtgcatg atcttatgct aacctatctg
     2941 tctcaaatct ttgacccatt gttatctatt tgatgttatg gctttcgcca actttagtat
     3001 catatcatat cttctatgta aagtaaagtt acttgacaaa aattttatta aaaagctctg
     3061 ctattctcca aaaatcctaa aaaatggtaa aatgagacaa aggtggttat tttaggagat
     3121 taagatgttt ggaaaattat taagtctgtt aggctttgtc gttgctttga ctggttgtgg
     3181 tgtttcacag gcagaaaaag aacgtgttgt aacagagtat agccccatta ttattaaaaa
     3241 atttcaaacc ttaggatacc aagggaaaat cactgtagac gactatacta agatgattga
     3301 gacaggtagt gagagacttt attttaccta cagcgaagaa gtagacggta aggttattag
     3361 tctgaaggat agtatttcga ttgctaccta taaatcacct gaggaagatt tggctgatgc
     3421 agaagttgac atgggaatta gggaagaagc tatgtggcag caaccagctg tcaaagcgca
     3481 agctgctcag atcaaacaac tatttagcga gttggagact gaggatttga agcttatatc
     3541 cgtaacagga caaagtgtcc agacgatttc tgattcagat ggagagctga ttagggaaga
     3601 tgttgtacga ggcaggaatg aattatctca agatgcatct aataatagag aagctgggct
     3661 atcaataggt ggctattatc atattgatgt ttcaaagtat ttgaaaaatc acgtgttgga
     3721 aattcgtata gattttgatt ggcgaatgtc agaagaggaa caagacgatt tgtctggccc
     3781 caggttggat ttttctgata gaataaaaag tctagacttt acctgcttgt gggatggcta
     3841 ctataaagtg gggtttgaca gggtgagtag atctaatcga agtggagata ttcaagatat
     3901 gattgtttta gatattcgag gcggtaaatt ggttcgtagc ttttctgtac tttaacagat
     3961 taatgaagct attctatggt aaaatatata aatactagta aaagaggaaa taaaatgaag
     4021 cttcaaaaac caaaaggaac acaggacatt ttgcctgtgg ctgctgctaa gtggcaatat
     4081 gttgaaggtg ttgcacgtga aacctttaag caataccatt atggtgaaat ccgaacacct
     4141 atgtttgagc attatgaggt cattagccga tcagtaggtg ataccactga tattgtgacc
     4201 aaggaaatgt atgacttcta tgataagggc gaccgtcata tcacacttcg tccagaagga
     4261 acagccccag ttgttcgttc gtatgtggaa aacaagctct ttgcgccaga ggttcaaaag
     4321 cctgtcaagc tgtattatat tgggtcaatg tttcgttatg agcgtccgca ggccggccgt
     4381 ttgcgtgaat ttcaccagat tggtgtagag tgctttggct ctgccaatcc tgccactgat
     4441 gttgagacga tcgccatggc ttatcacctc tttgaaaggc ttggtattaa agaggtgacc
     4501 ttgcatttga atagccttgg aaatgcagct agtcgcgcag cctatcgtca ggccttgatt
     4561 gattacctat ctccaatgcg tgagaccttg tccaaggata gtcagcgccg tttagatgaa
     4621 aaccctctgc gcgtgcttga ttccaaggaa aaagaggata agattgcagt agcaaatgcc
     4681 ccatctattc ttgattatct tgacgaggag agtcaggctc actttgatgc tgtgcgcagc
     4741 atgcttgaag tacttgctat tccttatgtt attgatacca atatggtgcg tgggcttgat
     4801 tattacaacc acacgatttt tgaattcatt acagaggtgg atcagtctga gctgacgatt
     4861 tgtgctggtg gtcgctatga tggtcttgtg gagtattttg gtggaccagc aacccctggc
     4921 tttggttttg gacttggttt ggaacgtctt ttgcttatcc ttgataagca aggcgttgaa
     4981 ctgccagtcg aagaaggctt ggacgtttac atagctgttt taggggctta cgccaatgtg
     5041 gcggcgctag ccttgacaca ggccattcgc cgtcaggggt tcaccgtaga acgcgattac
     5101 ctcggacgta aaatcaaagc acaattcaag tcagctgatg ctttcaaggc aaaggtagtc
     5161 atcaccctag gtgaaagtga aatcaaaaca ggtcaagctg tccttaagca taatcaaact
     5221 cgtcaagaga tgacagttag ctttgatcaa atccaaacaa attttgccag catttttgca
     5281 gaatgtatcc agtaaagcaa aaaaactgaa aaaagtggta tgagtcatta agatactaaa
     5341 aaatcacaca acgtcgttgc tttaatagca atgatattgt gtgattttgt gatgttatac
     5401 ctatactaag gactattttt cctattttta gtagtcagtt tgaaagcact cttgtttgga
     5461 atggcagcag ctatgcttat agctggtgat gggttaatgc tattgttgag aaactaaaac
     5521 aatgttagag aagataatgc tgactttata gatgttattg tctatggttt gctggtatag
     5581 tccataatac tgttgaacaa ttttttgaac atttttaatt cccaatccgt cttttttccg
     5641 ttgacttctg gaggcaagct cttttggatc aaaaaagttt tcgatatcaa tgtggagttg
     5701 atttttaaag agtctcacct ttaattgtat ttgtttttca gctttatttt gattgcgaat
     5761 agttgcggca atgctattat caagtagatt tcctataatg actgaaataa cttcagtctt
     5821 taggcttatg tttgtaggga taaggcagtg aatatctaac acaatgccat tctttttggc
     5881 tacgactgct ttttgattaa gtaaataatt taaaatagta tcattggtaa agaaagtatc
     5941 tgtcccatct agcaggttaa ggttatgatt cagtaattgt tgggctttag tgtactgctt
     6001 ttgctccaga agtcctaata ggacaatgtt ttgattatgt agatcatgct taagagccct
     6061 aatgcttaat tgattttcct ttacattttc taaatgcttc agttctgact ggaatcgtac
     6121 cctatctaag ttaatgtctt gcatttgtaa atgctgatct gaaatgtaag tatacagata
     6181 cagcgaagtg attgtgataa tgataaatcc aagtgttagc agtattgtaa acaagtcaaa
     6241 taaaggttct tcttttaatc gaaggagctg tagcagtagc agagaaagac ttatcattgg
     6301 aataatagat agctttagta tccagttggt ttgtgtttgc tcatcaagcc aattgtctgt
     6361 agtctttaaa aagagctgct ttaacacaaa tataatgata atactggata tggtaagcag
     6421 gtttataaat aaaaatgtcc cactgataga agagatttga tatttaagag atattaaaat
     6481 gatccctaag cttgcttcta gcaggatacc tatgctttga agtgtaacag accaaaagat
     6541 acactgtttc atggagtaac gatagctact agatattatc agtgatgtta ccaaagaaca
     6601 agtcagggtt atcagtgagg catagcttcc tgatacaaaa aaatgagtgc agcattctat
     6661 gaatactaaa aaagagagat aacctatgtt tttaaaggta gctagctgac catttttctg
     6721 acgaaaaaaa taattaacaa tcacaatatt aacaactgat gtataaagat gaaaaatagc
     6781 gttaatagcc atttactctc cttagcttgg aaaagatgtt ctcctgaata cccttcttaa
     6841 atttccgact gataggaatg ataaaaaagc gcgtgttatc aatagctaat gttatgtcat
     6901 tgttttcaaa tttatagaag taattgacgt taaacacata agaatgatgg gtttggataa
     6961 attgttcagg aagctctttt agtaatgctt tggttgataa aaaggtagag taggtcttgt
     7021 ccttggtatg aatgagtact tttcgtcctt ccttttcaaa atagataata tcgtttaagc
     7081 ttaagctata gtaggagtgg caagatgaaa aggtaaaaaa ttttttgtca agctctaaaa
     7141 cccttagagc tctatttagg cactcaaaaa aatagggttc atttaaaggc ttaatcaggt
     7201 aatcaaaggt ttgcacgtga aaaatgtttt ccatgtattc tttgtggctt gttaaaaaga
     7261 taataatagc agagagatta tctttcctaa tatgctcggc taatgctatt ccagacatgt
     7321 tatccatttc aatgtcaaga agaaaaatat ggtaatcatt agacagtgac tgtattaatt
     7381 gacaaggatc ctcgtaaatg tctaactcca ctggaactaa ttgattatat tggtataata
     7441 gatcttctac agctgttgca aaagctttat tgtcatcaca aagagcaatt ttaagcatgg
     7501 tacccccata atcctataga ctgtggtatt tagtatacca aaaatgacat gaaaagcgct
     7561 attttttaca aaataataat aatagactga atgttttgat aaaatgaatc tatgaaatga
     7621 gggagcaata atgactgaag taacagtgcg taaaccgatg gaaacaatgg aagtttcatg
     7681 ggtagtcatt taaatactct aaagtgggct gtttttatca gcctacttta atatttttag
     7741 gagggtaaaa aatgaattat agcagacctt gtattaaaga tatttatcca atttataaac
     7801 tgagtgatac catgtttcga ataggcgctc aaattaatat tacgacggaa tttaacgatt
     7861 caaattatga aacaggtgct tcatttacac ataagctttg gccacatttc aaagagtgtc
     7921 cggcttgtgg tcatggcaac agtaatgatt gggaaatatt tagtcattat gggtaggagt
     7981 taatcaatgg aacaatatga attaatggtg aggtcacttt caaaaaggta tgccagagat
     8041 ggctcttatg ccaataggga tttacattgt gtctttaaat ccagtgaaat aacagccttg
     8101 ataggtcata atggagctgg taaaacaact ctactaaacc agattattgg taatataaaa
     8161 cctgatgtgg gtgatatttc atttctagac tgttcgtttg tcaagtcccc taaaattgct
     8221 agaaaaaata cgtcaatgat gcctcagcta catgccccct taaaaggaat cacaattaaa
     8281 caggctattt catcaattgg aaaaatcaga gggctgtccg gaaaattatt ggagacagag
     8341 gttcaggaat taattcaaga actcggtctt attaagtggc aaaatactgt cggagagaaa
     8401 ctctctggtg gactaaaaag attgacgtcg tttgcaatgg ctgttattgc tgctccgaag
     8461 attgttttac tagatgagcc gacaaatgat gttgatccta taagacgtat aaaattatgg
     8521 ttatacttaa aaaagatggc ggcaaaggga catatcgtta ttgttgtcac ccataatatt
     8581 ttagaggttg aaaaatatgc agatgcttat tatttgcttg aaaaggggga agtaaaaagt
     8641 tcaggagcgg taaaaaccct atccagcaat ccaaagagta gaatatccat tttatttaga
     8701 gatcaaaaag ccttggaaga atacccattt gcttactcac ttggtgggga tgacaatgaa
     8761 gctataacaa taatggataa taaggaaatg acagcattat tgaattggtt aggcatacat
     8821 ttgtcatcag ataccattgt tcaatatagt atcacgacgt tagggttaaa tgattattat
     8881 gaggagctgt cagatgaaga agattagtgt tacttaccaa tttctaagct tgttaaattg
     8941 gagctttatt cgccataaat cgttgatatt attgtgtagc gttattcaat tttttatgac
     9001 aattgcactg gtttacggtt attcacttat tattgctgat gatactgtgc aaacagtcta
     9061 ctatcttgct tctggctcag taacgattgg tatgattacc attggctgta cggtatcagc
     9121 acaatcaatc agtagtgata aaagagatgg cattgtgagc tatattcaaa cgttacccgt
     9181 cctaagaagt ttgatcctgc tatctgatct attgatttgg acattaactg ctttgattgg
     9241 tgttggtgtg tcaattgcgg ttgtttattt aaaatttcaa atattgcccc agctgtcctt
     9301 agcgacgttt cttattttgc cattagtttt aatgacaatg atcagtatgg gttttgccat
     9361 tgcttattgg tcaactccaa gtacgatgat gctggtaacc caattattgt tgatgattgg
     9421 cttattgttt tcacctataa tgtatcctgc agaacgtata cctgaggtga ttttaagggg
     9481 atatcatttt ctgccattta taccagcagg agacttgatt cgagagacgg tttatttggg
     9541 gcattccatt tcagttgtca agcttgtggt gttactgtta tggctggttg ccactgcctt
     9601 actttcagtc aattggctaa acaggcaaag ctaaggtata ggctctgcta tttcttaaaa
     9661 actctactca aatgggtggg gtttttaatt gttttttgtt ataataagtg gtaatgatat
     9721 ttttaattag agaaaggaac aaagacaggt agggagtgtt gactctttat ttgctcttgg
     9781 tatcttattt atgaagcgta gcatgtatgc aggacacgtc cgaaaggaac atattggaag
     9841 aacgattgtt ttaaaaggtt gggtaagtcg ccgtcgtgat ttgggcggcc ttattttcat
     9901 tgatttgcgt gatcgtgaag gagtgatgca gctggttatt aatccagagg acgtttcagg
     9961 tgatgtgatg gcgactgctg agcgcttacg cagtgaatac gtgattgagg tggaaggaag
    10021 tgttgaggcg cgtcagcagg ctaatgataa gctagctaca ggtgcagtgg agctaaaggt
    10081 ttcaggcttg accattctta atacagctaa aacgacaccg tttgaaatca aggacggtgt
    10141 tgaggttagt gacgatacgc gtttacgcta ccgttattta gatcttcgtc gtccagaaat
    10201 gctggaaagc tttaagcttc gtgccaagac gacgcatgtt atccgtaatt acttggataa
    10261 tcttggattt attgatgttg agacaccgat gttgacaaag tcaacgccag agggagcgcg
    10321 tgattacctt gtaccaagcc gtatcagcca gggacatttc tatgctttac cgcaaagccc
    10381 acaaatcaca aagcaattgt taatgaatgc gggctttgat cgatattacc agattgttaa
    10441 gtgcttccgc gacgaagatt tacgaggaga tcgtcagcct gagtttacac aggttgactt
    10501 ggaaacgtca tttttatctg agcaagaaat ccaagatatt gttgagggta tgattgcaaa
    10561 ggttatgaag gatacaaagg gcatagaggt taagctgcca tttccgcgca tggcttatga
    10621 tgacgccatg aatcattatg gctcagataa gccagataca cgctttgata tgcttttaca
    10681 agacttgaca gatcttgtca aggagattga ctttaaggta ttttctgagg cacaggctgt
    10741 taaggcaatt gttgtcaaag gacatgcgga tcgctactcg cgaaaggaca ttgataagct
    10801 gacagaattt gctaagcaat ttggtgctaa gggtctggca tggctgaagg tggttgatgg
    10861 tgcatttact ggaccaattg ctaagttctt gacaggtgtg aaaagtaagt tgacagagtc
    10921 tttacagctt gagcataatg atttggtctt gtttgttgca gacaccttag aggtagccaa
    10981 caatacccta ggtgctcttc gtacacgtat tgcaaaagag cttgacatga ttgacatgtc
    11041 tcagtttaat ttcctatggg tggttgactg gcccatgttt gaatggtctg aagaagagga
    11101 gcgttacatg tctgctcatc acccatttac attaccaaca gcagagtcag cccatgagct
    11161 agagggtgat ttagccaagg ttcgcgctgt tgcttacgat attgtcttaa atggctatga
    11221 gcttggtggc ggaagccttc gtatcaacca aaaagacatg caagagcgta tgtttagagc
    11281 actaggcttc acagctgagg aggccaatga gcaatttggc ttcttactag aggctatgga
    11341 gtatggcttc ccaccacatg gtggtcttgc tattggtctt gatcggcttg tcatgctgct
    11401 tgctggcaag gacaacattc gagaggttat tgcctttcct aaaaacaata aagcatctga
    11461 tccaatgaca caggcgccta gtctggtatc tgaaaagcaa ttagaggagc ttcagcttca
    11521 aatagaacat catgattaaa aaaacaacct ataggaaaag agtaaaatac ctgattaata
    11581 gaggagccaa aaaaattggc ttgcttcatg ccgtaaaaag catttccaag gagaagtata
    11641 cagagaaaat ttcggcctct ttactctatg gcatattgtc tagtatagct gttaatttct
    11701 ttttccaacc gggccatgtc tactcaagtg gtgcaacagg acttgctcag gttatctctg
    11761 ccatcagcca ccatttatgg ggctttgaga ttcctgttgc tttagctttt tacgtgacta
    11821 acattcctct tttagtctta gcttggtata agattggtca taaatttacg atttttacct
    11881 ttattaccgt tagtatgagc tctttcttta tccaaatcat gcctcaggtg accttgacga
    11941 ctgacccact gattaatgct atatttggtg gcttggttat gggtttgggg atcggtacag
    12001 gcttcaagtc tcgcatttct agtggtggta cggacattat cagtctgaca cttagaaaga
    12061 aaacaggaaa agatgtcggt aacctttcat tgatgatcaa tggtgtgatt atggcttttg
    12121 caggactgtt gtttggctgg cagtatgcgc tttattcgat ggtgactatt ttcgtttcta
    12181 gtcgagtgac tgatgcgatt tttaccaagc aaaagaaaat gcaggcgacc attgtgacca
    12241 gctgtcctga caaggtgatc cacatgattc ataaaaagct gcaccgaggg gtaaccagta
    12301 tcaatgatgc tgaaggcacc tacaagcatg agcataaggc tgttttaatt acgattctca
    12361 cacgtgagga atatagtgaa tttaagtggc tgatgcttaa aacagatcca aatgcttttg
    12421 tttctgttgc tgaaaatgtt agaatcattg gtcgctttgt cgaatcagat gaagactaag
    12481 aaataggtat caatatgcca gctaataaga gcttaaagct taaaaattgt tgttttatta
    12541 ttcttggctc agctatttat gcctttgcct ttgtctactt ttacatggca aatcgtattg
    12601 ctgctaatgg gctagcggga ctgacgcagg ttgctaatgc cttgtttcag atcaatcctt
    12661 caataacggg ttatctgatt aatttgcctc tcgtcctgtt gggtgcaagg ctctttggca
    12721 gacgggcaat ggtgtatact gtgaccggta ttttatcact ttattggttt gtttggctgt
    12781 ttcaacagct cccccttttt attgacttag atcatgacaa tttagtagtg tccttgctgg
    12841 caggaattct tggtggttta ggtggcggca ttgtttttag aaatggtggg acgattggtg
    12901 gctcagatat tattgctaag ctgatagagg ataggtttgg cttgcagctc aatcaagcct
    12961 tattagggat tgatattttt gtcattgtgg tttctttgac ctatatttca ataccgcaga
    13021 tgatgtatgc tttgattgct agctttatgt atagtaggat tgttcatctg gtgcaaaatg
    13081 gtggctattc tgcacgcgga acctttatta tttcagatta ttctcagact atttcacaat
    13141 tcattatgga ggagctcggt agaggagtca cctatttaca tggtgagggt gcttactctg
    13201 gtcgtgagaa acaggttatt tatgtagctc taggtcgatc agatgtacga gagctaaagg
    13261 cctttatagc acaggttgat cccaatgctt ttgtttcttt ctttgatgtt aacgaagtca
    13321 atagtccaga atttattgcc acaaaaagta aataccataa aacgaaaaaa agataaaggc
    13381 tggaatatca cattcatagc ctttgattat gctaatgaaa gcgcttggct attaagctta
    13441 ttgtagtgta gctattaaat ggccgtcctt gagctttcat ctggtaccta acaaatgtaa
    13501 tgaatagtga ggaaagtgaa tgacaaatct tgacaaatgg catcgtgtaa gagagctatt
    13561 attaattgcg gtgggtgttg ctatctatac ctttggtttt gttaatttca acatggctaa
    13621 tgaattggct gagggtggcg tagctggaat taccttgatt ttgcatgctc attttgggat
    13681 caatccggct tattcgtcac ttttatttaa tctgccttta tttatgttag gggctaagat
    13741 ttttggaagg cgctccctag ccttaacgat ttatggaacc gttcttatgt cagtctttat
    13801 ctggctgtgg caaaaggtgc ctatggagct tggtttagag aatgatatga tgcttgttgc
    13861 ggttgttgca ggcttgtttg caggaattgg tagtggcctt gtttttcgat atggagcgac
    13921 aactggtggg actgatatta ttgcccgcat tgcagaggaa aagtttggtg ctaagctggg
    13981 gcaaaccctg ttatttgtag atgccttggt attaacagcc tctctcactt atgttgattt
    14041 gaagcatatg ctctatacat tagtggctag ctttgtcttt agccagatga ttagtgttgt
    14101 tcaaaatggt ggctatacca ttcgtggtat gattattatc actaagcagt cgcaagccgc
    14161 ggcgcaggcg atcttgacag aaatcaatcg aggagtgact tatttaaagg gacaaggcgc
    14221 ttattctggt catgattata atattatgta cgtgacgctc aatccaacag aggtgcgaga
    14281 ggtgaagcgt attttagcag agctagatcc agacgccttt atctctatta ttgatgttga
    14341 tgaggtaatc agctcagact tcaagattcg tcgcaaaaat tttgacaaac caattgagaa
    14401 ggctttacag aaaaaatcca acatgttaaa ataaagaaaa taagcagaaa taagaggttg
    14461 agaaaagcca tgattaacaa ttaactcatt gtcaagcact aatctatgat taacagcaag
    14521 ggattagtgt ctgctttgag gcttgggaat cagggctttt tgtgtgcact ttttcaggcc
    14581 tttctgatga tagaaaggaa taaatatgga agcacttagt attcagcatt acgctttaga
    14641 tacagcagaa aaaaacttat tgacaataga ttctcttaca ttgaatcaag gtgagagggt
    14701 tttcatcatt ggtgataatg gggctggaaa gaccagcttt ttaaagacaa ttatcggaga
    14761 aagcactaac tatagtggct ttttgcaggt gcatggagat attgcttatg ttccgcaaat
    14821 caagtccact agccctcagt caggaggtga gagggcgatg tcttacctaa aagaggcttt
    14881 tcaagcaagg ccttctctgt taattttaga tgagccaagc tcttatttag accatgctaa
    14941 tcgtgattgg ttgattaatc aattgaaacg ctaccgagga accttgctgg tggttagcca
    15001 tgatcggtat ttgatcaatc aattgagtca gaaaatatgg ttgcttgagc atcaaacgat
    15061 caagacttac catggcaatt atgatgatta tcagcgttct agacagctag aggaggataa
    15121 gcagctaaga gcttttctgg aataccaacg aaagactaat caactgaaaa aaagcctgac
    15181 cagaaaaaaa gtgcaggcca acaaaatggc tgtaaagaaa aagtcggttt ctcggtcaga
    15241 ttggaaaacc aattcctttg cgggcagcta tgattcacag gccaaggcta tggcaaaagc
    15301 agctaaagct atggaaaatc gactcactcg aatgaaagag gttaacagtc cgcgcaaaaa
    15361 ggcttgggca aaattaaaaa aggatccaaa cgaaggtgca ctaccaaata ctcttttaca
    15421 cctacaagaa ggtaccctta caagggacca tcagttattg tttgactatc ctggtattgt
    15481 gatcagatca catagcagga tagcgattat cgggagaaac aaggctggta aaagcagctt
    15541 tttagatcag ctggcagccc aggccttgtc tggattttat gcgcaaaatc taaggataac
    15601 ctattttaaa caggaccagg ctgacttgga gccggatcag acagcagtag agctcattag
    15661 tcggcagtcc agccaagata gggtcaccat tttaaattat ctagctatga tgggcattga
    15721 ttatgataag gccaatcaaa aggtagctgt cttatctggt ggggaaaggg ttcgtttggc
    15781 gttagtggct gccttgctga cagatcatca gcttttgatt ttagatgagc cgacaattta
    15841 tttggatctt gtcgctattg aggctttgga gtcttgcttg attgactatc cagctgctct
    15901 tttgttggtt tctcatgacc tagcatttgt taacaaggta gcaacagaaa tttatgaggt
    15961 taaggatcat catttaacag cctatcattt tgaagactag caaaaaagcc taggctagct
    16021 tatcctcgct agcttaggct tattagtcta catttcattt ggtgcctcaa cacccaatag
    16081 acgaagcgct tctttgagga cgattgcagt tgcatagcaa agcgctaagc ggttgtcacg
    16141 ttctggatcg tcttcgagga tacgggtatg cgcataatat ttgttaaagc tttgtgccaa
    16201 gtgaatagca aattttgcca tgattgatgg ctcaaagtta tcaaaagcac gcttgatgat
    16261 acgtgggaag tcctggataa gcttaatgat ttcccagctt tcaggatcat taaggctata
    16321 gcttgtatcg gtagctggcg taaagcttgc tttacgcagg atagattgga tacgtgcgtg
    16381 tgcatattgg acgtaaggac cggtttctcc ttcaaaggat accattgctt caagatcgaa
    16441 gtcatagcca ttcatacggt ctgtttttaa atcatagaac ttgatagctc ccacaccaac
    16501 agcatgagct actgcttcct tgttggcaag cttaggattt ttagcttcga tttggtttgc
    16561 tgctctgctg atggcttctg caaccgttgg ctcaagcaaa atgacattac ccttacgtgt
    16621 tgataatttt gcaccgccct ttgtcacaag gccaaaagca acgtgtgtca tgtcatctga
    16681 ccaatcgtag cccatttctt taagaacagc ctttaattgc ttgaagtgtg cagcttgctc
    16741 gttgccaacc acgtaaactg attttgcaaa atcataggta cgcttgcggt aaagggcagc
    16801 agctagatca cgagtaatat aaagcgtagc tccatctgat tttttaatga gagctgggtg
    16861 ctcaatacca tatttttcaa ggttaaccac cttagctccc ttagattcga ctagtaggcc
    16921 tttgtcctca agaagctcaa ggacctcatc cattttatca ttgtagaagg cttcaccatt
    16981 atagctatca aagctaactc ctagctggtc atagagtcgg ttaaactcaa tcaagctttc
    17041 atcgcggaac cactgccaaa gctctgtagc ctcttgatct ctctcctcta gcctgcggaa
    17101 ccattcacgt gcctcctcat caagactagg atcagtttct gcctctgcat tgattctcac
    17161 atagagcttt aagagctcat caattgggtg tgcttgaaca gcggcctcat ttccccactt
    17221 cttatacgct acaatgagca taccgaattg cttgccccag tcacctaggt gattgatttt
    17281 aacaggctta tagcccattt ttgcaaagat atgagcaaga ctgtccccga taactgttga
    17341 gcgcaggtga ccgattgaaa atggcttagc aatgttaggg ctggacatat caatagcaat
    17401 atgacgtcct tgtccttcat cctgttgagc atagtcagct ccgtcagcaa tcacctgtgt
    17461 aagaacctgt gcagaaatgc tagccttatc taaaaagaaa ttgacataag gaccaacagc
    17521 agcaaccttc tcaaattggc tggcgtcaat cctttcagct aaatcactag caatagcttg
    17581 tggtgctttg cgaagcgcct ttgctagact aaaggctgga aaggctaagt ctcccatgtc
    17641 agaatttttg ggtgtttcaa gtaagttaaa aatggcagcc tgctctagtt caggaacaat
    17701 cttagcaatc tcagctgcaa tcagagtttt agtgtccata ttgcttctcc taaaaatagt
    17761 ttgtcaccct attctaacac atttcttgga aataaacgag gtgtctattg agaaattata
    17821 ctagaaggct tgtaggtgtt ttggggaaca aagctaaaga attagagcag caaagcttgc
    17881 caaatctaag ggtctaatga tatgagcaag aaataatgct tccttaaaat aaagcaaatt
    17941 gacagagctg agatgaaata ctaccatttt tttgttataa tttgagagga taattataca
    18001 ttggggagat atatcatgaa taaaatagaa cggcagcagc aaatcaagca acttattcag
    18061 gctgagcaca tcggtacaca ggaggagatt agacggcttc ttcaaaagga tggtatcgtg
    18121 gtcactcagg ctaccctatc acgagattta agagaaatcg gattacttaa attaagagat
    18181 gacagaggta agctatacta tagtctttct gagcctgttg ccacaccatt tagtccagat
    18241 gtgcgctttt atgtcctaaa ggttgaccgg gcgggcttta tgctggttct ccataccaat
    18301 ctgggagaag cagacgtgtt ggcaaatctt attgacaatg atgccattga ggacgttttg
    18361 ggcacgattg cgggtgctga taccttactt gttatttgtc gtgatgagga gattgccaag
    18421 cgctttgaaa aagatttagc tgctggtcta taatatgcct taccgcgaat ccttacatca
    18481 gctgatagca gcactggaaa agcactcaag cattatagct tataaggagg ctcagcagca
    18541 cttgcttcaa aggactgatt ataatcaaaa ggcctatcag atgaagcgac atcaacagga
    18601 cacctatctt tttcgtcaaa tcgctaagga taaagcagct gaagaatcag cttttaaggc
    18661 tcagcaatta cgagaagatt tagatcatca accattgata gatgattatc gtgacaaaat
    18721 gcaaaacgct agtgacttgg ttcggtacat tacagggact atagaagatg aattaaataa
    18781 ggagttcaat gatggcaaag gctaatgttt ctcccggaat gcagcagtat ctggacatca
    18841 aaaaggatta tccagatgct tttttgcttt ttaggatggg agatttttat gagttatttt
    18901 atgaagacgc tgttaaggca gcgcagattt tagaaatcgg cttaaccagt cgtaataaaa
    18961 atgctgacaa cccaattcca atggcaggtg ttccctatca ttctgtccaa caatacatcg
    19021 atgttttaat tgatttgggg cataaggttg ctattgctga gcagatggag gatcctaagc
    19081 aagcggtcgg tgttgttaag cgtgaggtgg ttcaggtcat taccccaggg acagctgtgg
    19141 actcaagcag acctgatagt cccaataatt ttttggtggc tgttgatttt gatggcaagg
    19201 cttatggcct gtcttatatg gacgtctcta caggagaatt ttttgctaca gacctagcag
    19261 attttgccag tgtcaaaagt gagattcaaa acctgaaggc aaaagaggtt cttttaggct
    19321 ttgaattatc tgaagaagag caggctattt tagtaaagca gctgaatctt ttgctgtcct
    19381 ttgagatgac agcactagag gattcgcctt tgattgatca tcagctaaca gcagtcgagc
    19441 tgtctgcagc aggtaagctg ctacactatg ttcatcaaac ccagctgcgt gagcttagcc
    19501 atctacaggc cttggtgcac tatgatatta aggattattt gcagatgtct tatgcaacca
    19561 aatcaagcct tgacctgctt gaaaatgctc gtactggtaa aaagcatggg agcctttatt
    19621 ggttgcttga tgaaaccaaa acagccatgg gtatgcgtct attaagggct tggattgata
    19681 ggccacttgt gactagtgag gcgatcctag aacgtcagga aattatccag gtgtttctta
    19741 atgcttttat cgaaaggaca gatctaagcg atagtttaaa gggtgtttac gacattgagc
    19801 gcttgtctag tcgtgtatct tttggaaaag caaaccccaa ggatctatta cagctaggtc
    19861 atactttggc caaagttcct tatatcaagg ctatcttaga ggcctttaac agtccttacc
    19921 ttgacaagct tgtcaaccaa attgacactt tgcctgagct agagcacctg atacggtcag
    19981 ctatagatcc agatgctcct gctactatca atgaaggcaa tattatcaga acaggctttg
    20041 atgaacggct ggatcattac cgaaaggtca tgcgagaagg caccggctgg attgctgata
    20101 ttgagacaaa agaaagacag gccagtggga taagcaatct caaaatcgac tataacaaaa
    20161 aagatggcta ctattttcat gtgaccaact ctaatctagg tatggttcct gaccattttt
    20221 ttagaaaggc aacattgaaa aattctgagc gctatgggac agcagagcta gctaagattg
    20281 aaggacaaat gcttgaggct agagaggagt catctagcct ggaatatgat attttcatgc
    20341 gtattcgtgc tcaagtggag acctacatcg ataggctgca gcagctagca aaagctctag
    20401 caactgttga tgtcctacaa agcttagcag tggtcgcaga gaagaatcac tatgttcgac
    20461 cattatttaa tcaagagagc aagattgcga ttgacaatgg tcggcatgct gttgttgaaa
    20521 aggttctagg tgttcaggag tatattccaa acagcatttc ctttggtcca cagacaagca
    20581 ttcagctcat tacaggacca aacatgagtg ggaagtctac gtatatgaga cagcttgctt
    20641 tgacagtcat tatggctcag ataggctcat ttgtagctgc agaatctgct agcctgcctt
    20701 tatttgacgc tatttttact aggattggtg cagcagatga tttgatctca ggccagtcta
    20761 cattcatggt tgagatgatg gaggctaatc atgctatcaa gcgagcaacc cctcattccc
    20821 tgattttgtt tgatgagtta gggcgtggta cagcgaccta tgatggtatg gcactagccc
    20881 agtctatcat cgaatacatt catgatagag ttggtgcaaa gactatgttt gcgacccatt
    20941 atcatgaatt gacagagctg tcaaccaagt tgacaaagct ggttaatgtt catgttgcga
    21001 cgttagaaaa agatggaaat gtaaccttcc tgcataagat tgccgaaggt cctgctgata
    21061 aatcctatgg gattcatgtg gcgagaatag ctggattgcc agaggattta ctagccagag
    21121 ctgatactgt gctaaccaag ctggaagctc aatcacaagc aagagagtcc gtcttatcaa
    21181 ctacagaagt aagagagact cagcagctgg ctaatcagca gctatcactt tttacagatg
    21241 atggctcctc tagcgagatt attaaaaggc ttgagagtgt tgatgtgatg aatctaactc
    21301 ccattcaggc catgaccgtt ctttatgagc taaaaaagct actgtaaaag ctagtatcag
    21361 atgttaaagg cacttgtagg ctcaccaggc cacaggtgct ttttggttta ttgaccataa
    21421 gacccttgct agctctgatg cttggctctt ttagttttat gttataatag tccataagaa
    21481 tgcgaggaaa tatatgacaa caattatcga attacctgag gttctcgcca atcaaattgc
    21541 agctggtgaa gtcattgaaa gaccagcaag tgttgttaaa gaattggttg agaacgccat
    21601 agatgcaaag agtagtcaga ttactgttga aatagaagag tctggcttga aaatgattca
    21661 aatcactgac aatggcgaag ggatgtctca cgaggacctg cccctgagcc tgcgtcgtca
    21721 tgccacaagt aaaatcaaaa gtcaaagtga tttgttcaga atcagaacac ttggctttcg
    21781 aggagaagct ttgccttcgg ttgcctctat cagtaaacta acgatcaaaa cagcaacagc
    21841 tgatgcagag catgggtcaa tattagttgc tagtggcggt aagattgagc agctggaagc
    21901 tgtctcaaca cctgttggta caaaaatcaa ggtagaaaac ctattttaca atacaccagc
    21961 tagactgaaa tacatgaaga gcttacaagc ggagctggct catgttgttg atgtcgtcaa
    22021 tcgcttgagc ctggctcacc cagagattgc ttttacattg atcagtgatg gcaagcagct
    22081 aacacaaacc tctggggctg gggatttacg tcaagcgctt gctggtatct atggcctgaa
    22141 tactgctaaa aaaatgattg acatttctag tgctgattta gattttgaag tgggaggctt
    22201 tgtgagtctg ccagagctga caagagctaa tcgtaattac attactatcc tgatcaatgg
    22261 tcgctatatt aaaaatttct tgttaaatcg agccatttta gatggttatg gctctaagct
    22321 gatggtggga cgctttccta tagctgtcat tgatattcaa attgatcctt atctggcaga
    22381 tgttaatgtt cacccaacca agcaggaaat tagaatttct aaggagcgtg aattaatggc
    22441 tctgattagt acagctattt cagagagcct acgagaacaa gacttgattc ctgatgcctt
    22501 ggaaaattta gctaggtcca gcacacgttc attttcaaag cctgagcaga ccagtttgcc
    22561 tttacagcct agtcagcttt attatgatcc gcaaaaaaat gatttcttta ccaaagaaac
    22621 agtggtttca gaggatagcc cgcagggctt taaccatgaa actttggttg acagtggtgt
    22681 caagcaggtt gacaatttgc agctggccaa gactgaatct gaagcagctg ctccaagtgt
    22741 taaatatgct agtcggccag atcctatgct ttctgatggt gagcacccgg gtcttgatgt
    22801 ccacaataag caaaaattat ctcagatgct tgatcgttta gaaaatgaag agcagtcggt
    22861 ctttccagag cttgattatt ttggccaaat gcatgggacc tacctttttg cccaaggcag
    22921 agatggcttg tttatcattg atcagcacgc agctcaggag cgcgtcaagt atgagtatta
    22981 tcgtgacaag attggtgagg ttgacaatag cctacaacaa ttgctggtgc cttatctgtt
    23041 tgagttttcc ggatcagatt ttattaatct tcaggaaaaa atgtcgcttt tgaacgaggt
    23101 tggtatttat ttagagcctt atggcaatca tacctttatc cttagggagc accctatttg
    23161 gatgaaggag gcagagattg aatctggtgt ttatgaaatg tgtgacatgc tgctgttgac
    23221 aaatgaagta tccatcaaaa cttatcgtgc tgagctagcg attatgatga gctgtaaacg
    23281 ttccatcaag gcaaaccata gcttagatga ttattcagca agacagctgc ttttacagct
    23341 tgctcaatgt aaaaacccct ataactgccc acatggtaga cctgttttga ttaacttcag
    23401 caaggcggac atggaaaaaa tgttccgtcg tatccaagaa aatcacacca gcttgagaga
    23461 attgggcaaa tactagagag gatagcatgc gagaattttt ccagttacct aagcaaatac
    23521 aaattcggca atttgtgcgc tttattacca ttacgcttgg cagtagtatc tttcctttta
    23581 tggcgatgta ctatacaagc tactttggcg ccttttggac aggcatacta atgatggtga
    23641 ctagctttac aggctttatt gggaccttat atggaggtca tttgtcagat gctattggtc
    23701 gtaagaaggt aattatgctt ggttcagttg cgagcacctt aggctggctg ctgaccattt
    23761 tggccaatgt tccaaagacg gttcttcctt ggttgacctt tgtgggaatt ttgctggttg
    23821 agcttgcttc cagcttttac gctcctgcct atgaggctat gctgattgat ttaacagatg
    23881 atagcaatcg tcgctttgtt tataccatta attactggtt tattaatata gccattatgc
    23941 ttggtgcagg tatttcagga cttttttatg atcggtattt cttagaactg ttgattgctt
    24001 tactgattat taatatcgtc tgctttggta ttgcctatcg ttattttggt gaaacgaggc
    24061 ctgagcatta ccgctttgag catggtattg gtattctagc aggttttgct aactaccggc
    24121 aagtctttaa ggatcgcgct tttgtgttat ttactatagg gacgatttta tttagcagta
    24181 tttggttgca gatggacaat tacgttccgg ttcaccttaa gctgtatttt gaagagactg
    24241 atgtgctcgg tattcatctg actagctcaa aaatgctgtc actgatggtc tttaccaata
    24301 ccttgctgat tgtgctgttg atgacagtta ttaatcgctt gacagcaagg tggagattat
    24361 taccacagct ggtgatcgga tcggttattt ttgcctttgg tatgctgttg tcatttacat
    24421 ttactggctt ttttgctatt tggtgttcag ttgtggtgtt taccattggt gaaatgctaa
    24481 atgtccctgc caatcaagtg ttaagagcag aaatgatgga tcagtctaaa attggctcct
    24541 acacaggctt tgtctcgatg gcccagcctt tgggagctat tctagcaggt ttgctggttt
    24601 ctcttagtca ttttacagga caggctggtg ttcagctagc atttgttttg attgcctgtg
    24661 tggggcttta tgtgattgtt ttatctgcga aaatgaagaa aaaggtgtag tatgtacgat
    24721 tatattaaag gtcagctaac aaaaattact gcaaagtata ttgtggtaga agcaaatggt
    24781 ttaggctata tgataactgt tgccaatcct tatagcttta cagactgtgt caaccagcag
    24841 gtaacgatct atcttcatca ggtgatcaga gaagatgctc agctgctgtt tggttttcac
    24901 agtgaggaag aaaaggacgt ttttttgaag ctgatttcgg tatcaggtat cggaccgacg
    24961 actgccctag ctattgtagc tgtagatgat aatagaggac tcgtcaatgc cattgataat
    25021 agtgatatta catatttgat gaggttccct aaaatcggaa aaaaaacagc tcagcaaatg
    25081 gtgcttgatt tagcaggtaa gttcgttgaa gcacctaagg aggaaagcag caagccccct
    25141 aaagccaagc aacaggggaa tgaacagctt gatgaggctg tcgaagccct attagccctt
    25201 ggatataagg cgacagagct aaagaaaatt cgagccttct ttgagggaac aagtgagaca
    25261 gctgagcagt atatcaaatc agctctgaaa atgctaatga aaggctagga gcttcatatg
    25321 aaacgttgcg catgggtacc acaagataat aagctttatt gtgattacca tgacttggag
    25381 tggggaaggc ctgtctatga tgatcgcgct ctttttgagc tgctttgtct tgaaagctat
    25441 cagtcaggct tatcttggtt aactgttttg aaaaaacgtc cagccttcag aagtgttttt
    25501 catcattatg atatctcagc tgtggcaagc tttagtgagc aggaaatggc tgctgccctg
    25561 caaaatgcag caattatccg acacaagcca aagctaatag ccactgtcaa caatgcagcg
    25621 gcagtccagc gcatccaaca agagtatggt agcttttcca gctatctttg gaactttgta
    25681 ggaggtcagc caattgacag gcttgtcaac gatgacaacc cagcgcccgc tcaaacagcc
    25741 ctatctctca agctatctaa ggacttgaaa aaacgtggct ttaagtggct aggaccaaca
    25801 actgtttatt cctttatgca ggcagcagga ttggtcaatg accatgaaga gaactgtgag
    25861 tttaggtaga attaatcgcc tctttggagt gatgtttcat gagcctatca aagagagctt
    25921 gataaaaaca gcccaatctt gattgcttat aggatgatgt ataagagcta tgtttttgct
    25981 ccgtacttta aggatagatg atgaatcccc ttatttaccc tgtagcgaat gttgtaagct
    26041 tctaatgggt ttaaggtttt agcctgttac tgctattgcc agtaagctac agtttgatca
    26101 ggtagttata ttggattgcc tcaacgattg tgttgctgct ggctggtgct tctttctata
    26161 acttattttg gtgcatgtga ttgtggctct aaaagttata acagagtatc ggtacgattg
    26221 gtgttacccc ttggtttcta tttttttctt atcagccagt ctggcattta cagcctataa
    26281 taaaagctac cgcttaaaaa tttcttagcg gtagtttttt agttcatgtt gcaaggtttc
    26341 tagaagttca gtttcttctg tcaactgtag taattgtaag cctttattaa ttaggtgatc
    26401 atcattacga caaataccga gacgaacttg ggaaaaacct aagctatcat agcgtttaag
    26461 ctgtctagct aatttgattg ttagtaaggt aatttcttcg cactcctttt tgaggttgtg
    26521 atagaggtaa atggttgaaa gattggttag taaagcatat tcagatgatt tgatattgcg
    26581 gtaatcttta tattttgcta ggctatctag gattttttga ctgatgtttt caattatttc
    26641 gataggaaag tgaaaaagaa tggtatgtag taattgtaaa tctttctcat accaagtatc
    26701 ttgttttacg agggaattcc agattttata agctagctct tgtaaatctt gattgttttt
    26761 aacgcctttt ttcctaagac ttatcatgac ttcgacacta tctaaaatat aagaaatggg
    26821 aatatcattt ttatttttaa ggtaattgaa gcatttttga cgtaattttt ctaattcagt
    26881 aatatttaca gctgatacct gattataaaa ttggtttaaa atgtcctgcc ttgtgctagg
    26941 atgataagtg ttgcagacat atctaaactc ttccagtgtc atattgagtt ggtttaataa
    27001 aaaaatcatt gtatcaaatt taggaatgac ttgtccgctt tcaatacgag ctagtgtaga
    27061 acgagctaaa aagtctccac agatcttttc ttgtgttaat cctttagatt ttcgtatagc
    27121 ttgataaatt ttaccgtaat cccaacgcat aaaacacctc taaaatgtta ctaaatgcta
    27181 caaaaaaata aaatctacaa tagtatttta taatagcatt tagaaagagt aaaggaggaa
    27241 aatttatgag gagacatcta aaggttgtat tattacttgc agcactattg gcatttattg
    27301 taaatgaggg taattttcca tggtggcctt ggggaccata gtacttaact gattactgtt
    27361 atgttgttgc cattagacta tctagattaa tcaaagagta aaatacaagt agcttagtga
    27421 aagacatttt aagaggagaa aagcatatga agaaacgttt agcatttata ttagttgctt
    27481 ttggtatttt gggatttagt ttaggaaatg aagttttagc tgcagatact gcacctgcaa
    27541 gtgcaactat ggcaacagat agtgatgtga gtttttacaa tggagaactg ttgaaaaaat
    27601 atttggtcca aagtggtgat agattgtatt ttgattatga caaagctatt caagataaag
    27661 tttctgatgg tgtaatagat atgggattcc ttgttgagac aattagtgag gactattcac
    27721 aacaaacgtt tacctctcga aagtatttca aggcaggatg gcagctttat ggtaattatt
    27781 gtggacctgg ccataacgga aatcatttta ctttacctgt tattgatgtt ttagatcaag
    27841 gctgtcaaaa tcatgacagt tgttatcgat ggggagctgg gattggtgca aattgtgaat
    27901 gcaatcgtca gttagtaaat tacattaaag tatatcgacg gtggatgcca gctcatgcct
    27961 tgggggttgc tgatgctatt agagtatatt ttgaaacggt aggtgctatt ggatgttaac
    28021 cttaaaaaat attatcaatc gatactacat gtattatgta ttccttattg ttgtgatctg
    28081 gattgggatg ttttttgtac gatgggatac tactgtggct ggtgtattac tctatccact
    28141 gattatgaag caggtattta tcgtactagg agtagttgcg atgataatgg ccattatttc
    28201 tagaaaaatt gttcttggaa tttttggttt actatgctgt gctgcttttt ggattaatct
    28261 tttcttagct ttctatctat tacctggact tttgggaaat tagcgattaa actgtttttg
    28321 atgttttgaa gatgagaaac agattgtttt tctgtaaggc ttcctgttac ttctcaaatg
    28381 ctttggagta tctctttatc atttgttcac tgttgacaac gttaaaaaga ttattccaaa
    28441 catgggaatt gctgcttcag ggtattcctt gttaatattg gattgattag ttgttattta
    28501 tgcaaaatcc ttagagcatt gctttctcat tcttggttca tttgaataaa atgtaactaa
    28561 aaaaactttg taatcaattc aaattgtcac aagtataaaa gtaaaaaagc gactttgtta
    28621 gtgatctgat attcggaagt cctatcattg ctcgcttttt gttttttgag gttgattttt
    28681 attccgaaat tgttgtgaat aagtgcaatt ttaagctaag aattacctaa aatcttttga
    28741 agattactgc ttagcttcta atacctattt atcggtgtgt tgataattgg agagatagcg
    28801 ggattgtcat atgaaataaa ttttagaaaa tttaaacaag ttattctgat tattattatt
    28861 tcaacataag tctttatttg attatcattg aaaaccatta attcatctaa aattatttca
    28921 atgcttcatg gatgattctt tttttgttaa aatgagattg aatgtcgaat agataagtag
    28981 gtgggaaaat gaaagctgaa ctcattgcgg tgggaaccga gattctgact ggtcagattg
    29041 tgaataccaa tgctcaattt ttatcagaaa aaatggcgga gcttggtatt gatgtttatt
    29101 ttcaaacagc tgtaggagat aatgaagagc gtttgctttc tgttattgat attgctagcc
    29161 agcgaagtga tttagtgatt ttatgtggtg gtcttggtcc aacagatgat gatctaacga
    29221 agcagacctt agctaagtat ctgggaaaag ctttggtctt tgatgagcag gcaggtcaaa
    29281 aattagatgc tttttttgca catcgtaagc aggctgctag gacaccaaat aaccaacgtc
    29341 aggcgcagct gattgaaggc tctattgctt tgcaaaatca aacaggactt gcagtaggtg
    29401 ggttaataac tgtagatagg gtaacctatg ttgtcttacc agggcctcca agtgagctaa
    29461 agcctatggt aaaaaatgag ctggtgcccc ttctttcagc tagtcatgcc agtctatatt
    29521 caagagtgct gcgttttttt ggcattggtg aaagtcaact ggtgactgct ctggaggatt
    29581 tgattaagca tcaaacagat cctactattg ctccttatgc aaagaccggc gaggtaacac
    29641 tgcgactatc cacaaaggct gacaaccaag cattagctga tgaaaggctg aatcgactag
    29701 aggcgcagct cttatccata agaactgtag ataatcaacc cttacggcgt ttgctttatg
    29761 gctatgggga ggataattcc ttggcgcgtg agacctttga gctattgaag cgaagtggta
    29821 agacgataac agcagctgaa agcttaacag caggactgtt tcaagctcag ttaactgatt
    29881 ttgcgggagc ttcacaggtg tttaacggtg gctttatcac ctacagcatt gaagaaaaag
    29941 caagaatgct tggcattcca ttgggtgagc tacaaaggca tggtgttgtg agctctttta
    30001 cagctgagca aatggctgca caggcacgct gcttgaccaa ttcagatatc ggtattggtc
    30061 taacaggtgt tgctggtcca gaggcactcg agggacagcc agcaggaaca gttttcattg
    30121 gccttgccac taagaataag gtagaatctc ttaaagttgt tataggaggc cgtagccgtt
    30181 tggacgtgcg gtatattgct gccctatatg cttttaatat ggttcgtaaa actttattaa
    30241 aatcagagaa tttgctataa ttaggatagt gtattttagg aaattagtaa ctagacagat
    30301 gtgaggttat gctgtttatt gcttgctagt cagcctaaat agaggagaaa atattggcaa
    30361 aaaaagttaa aaaaaatgaa gaaatcacca aaaaatttgg tgatgaacgt cgtaaagcac
    30421 ttgatgatgc gttaaagaac atcgaaaaag attttggtaa gggtgcggtt atgcgccttg
    30481 gtgagcgtgc agagcaaaag gttcaggtga tgagttcagg cagtcttgct ttagacattg
    30541 cgcttggagc aggtggctat cctaaagggc gtattattga aatctatgga ccagagtctt
    30601 ctggtaaaac aacagttgcc ctgcatgcag tagcgcaggc tcaaaaagaa ggtggtattg
    30661 cagccttcat tgatgcggag catgccttgg accctgctta tgctgcggcg ctgggtgtta
    30721 atattgatga gctgcttttg tcacagccgg attctggtga gcaaggactt gagatagcag
    30781 gtaaactgat tgattctggt gctgttgatt tggttgttgt cgactctgtt gcagctctag
    30841 tgcctcgtgc tgagattgat ggtgatattg gtgataacca tgttggcttg caggctcgta
    30901 tgatgagtca ggcgatgcgt aagctttcag cctcaatcaa taaaaccaag acaattgcga
    30961 tctttattaa ccagctgcgt gaaaaggtag gggttatgtt tggtaatcca gagacgacac
    31021 caggtggtcg tgctttgaaa ttctatgcct ctgtccgtct ggatgttcgt ggaacaacac
    31081 aaataaaagg aactggagat caaaaagaca gtagtattgg taaggaaacc aagattaagg
    31141 ttgttaagaa taaggttgct ccgccattta aggtggctga ggttgaaatc atgtatggag
    31201 aaggcatctc acgtacaggt gagctgatta aaattgcttc agatttagac attattcaaa
    31261 aggctggtgc ttggttctct tataacggtg aaaaaattgg tcagggctct gaaaatgcca
    31321 agagatattt ggctgatcac ccagagctgt ttgatgagat tgaccataag gtgcgtgtta
    31381 aatttggctt gcttgaagat actgaggaaa gtgcagctgc agatacagtt gcagccaaag
    31441 cagatgagtt ggttttagag ctagacgatg ccattgaaat tgaggattag tgcttagtat
    31501 tagattttca gataaaggtg ctaaaaaggg cttaacagcg atcgtcaagc cctttttagc
    31561 ttgtgtttaa tcaagctctg tattggtctg ctcaggagct aggctgtacg cttggataat
    31621 ttgttagctg agtttatgtt ttctttaggg attaactgtt aagctataaa agccctagaa
    31681 aaaagggact tcctacagac aagatagtgg catagtaagc ttgcttgcaa ctagctcaat
    31741 ataggatttt ggccttggtt aaagggatca taaaagaaaa ctaaaaaata ggtccaaaga
    31801 ccgatattga ttagaaaaaa actatgctac aatagaggta tcacgagata gaaagtgaga
    31861 acaacatgat aaaaatttac acgatttcaa gttgtacgag ctgtaaaaag gctaaaacct
    31921 ggctgaatgc ccataagctc ccatataaag aacagaattt aggaaaagaa cctctttcaa
    31981 gagaagaaat tttagctatt ttatcaaaga ctgaaaacgg tgtggagagt attgtctctt
    32041 ctaaaaatcg ttatgccaaa gccttaaatt gtgatattga cgagttaagc gtaaatgagg
    32101 ttattgattt gattcaggat aatccccgta ttttaaaaag tccgattctt atcgatgaca
    32161 agcgtcttca ggtgggctac aaggaagacg atattcgtgc ctttttacct cgttctattc
    32221 gtaatattga aaatgcagag gcgcgtttac gcgctgcctt ataaaaagct ctgtcagagc
    32281 tttttttaat atcctaacaa atctgaattc ttgtttattc aataaaaata agctataata
    32341 gagcgtagca cttaaagtta gaaagaaggt gtaagtatgg gatttacaga tgaaacagtc
    32401 cgctttaatt tagacgatgg tgataaaaag cagattagcg aaacgctgac ggcagtttat
    32461 cattcactag atgaaaaagg ctacaatccg attaatcaaa ttgtaggtta tgtactaagc
    32521 ggggacccag cttatgttcc tcgttacaat gatgctcgca accaaattcg taaatatgag
    32581 cgcgatgaga tcgtagaaga gcttgttcgc tattatttgc aaggaaatgg aatagatatt
    32641 agatgagaat aatgggactt gatgtcggtt ctaagaccgt cggtgtggca attagtgatc
    32701 cacttggttt tactgcccaa ggactagaga ttattaggat caatgaagat aaacaggatt
    32761 ttggctttga tagattagct gagcttgtta agcaatatca ggttgatcga tttgtcattg
    32821 gcttgccaaa gaatatgaat aacactagtg gcccacgtgt tgaagcaagt aaggcttatg
    32881 gagataagat tgaggagctc tttcacattc cggtttctta tcaagatgag cgcttgacaa
    32941 ctgttgaggc agagcgtatg ttgattgagc aggcagacat cagtcgtggt aaacgtaaaa
    33001 aagtaatcga taagctggct gcgcagctga ttttacagaa ttatttagat tgtaactatt
    33061 aaggagaaca gatgacacat aatcatgatc acgaacacga agtcattaca cttgtcgatg
    33121 agcaaggaaa tgaagcattg tttgaaattt tattaaccat cgatggacgt gaagaattcg
    33181 gtaaaaacta tgttttacta gttcctgctg gttcgcaaga ggatgaatca ggagaggttg
    33241 agattcaggc ctattcattt acagaaaatg aagacggaac agagggtgat ttacagccaa
    33301 ttccagagga ttcagacgct gagtgggata tgattgagga agtctttaat agcttcttag
    33361 acgaagagta acaacctgag gcattagctt taaaataata aatagcctag aatcttggtg
    33421 ctagcagcat gggttttagg ctatttttat ggtttatcag acagtaggag tgatagctat
    33481 ttctatgacc tctaaatagc ctactgttaa gagtgttttt agggtcttgt agatgttgca
    33541 atagcctgta atttcgttga agttacttgc tgttgtcttt tttagtttaa gccttaacaa
    33601 agcttatagg aaatgactca acttagcaca gcataagccg cttattttga taagtaaaga
    33661 aatagccaat agctactttt agcttaaagc tgatcattac cagtaccctt agcttttctg
    33721 ggtattattt cgaataatct taatgggggt gattttatca aaagactcag tcaagaagaa
    33781 aaaagctttc taaagcatta taggctaaag acactgcacc gctttaaaga gctgctgact
    33841 tatgccagca tttgtcataa attgactaaa taatagattt tgctatactt gtaatatgac
    33901 atgtcaagga gaaacacatt gagtcaatta catcaagaag ttatgctgga aaaggtcaat
    33961 tatttggtga aagaccaccc atcgtcacat acgactaagt atgacatgaa ggtccctagt
    34021 ttatataaat tttatatctt tttctttagc atcatagcga gcttgcttac ggttgcggtt
    34081 cctttttttg cagatactgc aaatagcgtt cagtcacaaa atttatacat cggaatgatg
    34141 ttgactaaag gtcagattcc atatagtgac ttgtttacaa caggaggctt tctgtttttt
    34201 gtgctcatag ctttgagcta tcacttggga acaacggtat ggttggtact tgttcaagcg
    34261 ctgtgctttt atttgacagg tgtttatttc tataaattaa tccattatgt gacaggtatt
    34321 cagaaggtgg ctttaggttt tacagctatc tattacctat tgtctattag tcttggattt
    34381 ggtggcttat atgcgatcca gcttgccctg ccttttgtct tggtatcgct ttggttttta
    34441 accaagtatt ttgctggctt ggtaaaggac gaggccttta ttctctttgg ctttgcagcg
    34501 gcaatagcca tgctaattga gcctaggacg cttctttttt ggctgcttgc ctgcattgcg
    34561 attattgctt ataatgtgtc tcaaaagcat ttcgctcgag gcttttatca gctgttagca
    34621 gctatttttg gaatgctttt ggtgttttat acagcaggct attttatcct caatttacag
    34681 attttgagtc cttatttgga gcaggcgctt gtttatccgt ttagttattt tgtgacaggt
    34741 gatttatcgc tgattctcgg tttaacagtc caattaggac ttgttcttgg cttgggactg
    34801 ttaacggggc tgctgacgtt tatgaagcag cctaagctag agtctgatct tgctatgaaa
    34861 tggctactag tctttgttgt gtttagctat gctggtattg cggctatatc gcatgatttt
    34921 catacttatc acctactgcc tttactgcct tatgctttga tcttgctatc aagctctgtt
    34981 ggccgacaat atgaggcagg acttaggatg gttagtcatc gtcgtcgtaa ggggaaaaat
    35041 ggtgcgagac gggttattgc tatttatcta aataagcatt tctacgtgcc agcaatcata
    35101 atgctaggag cggtttttgg cacagcttat cagtatgtga ccagctctgc tattaatcaa
    35161 gagcgttctc agattgctca ctatctaaga cagaggctaa cggaggacca acccatctat
    35221 gtatgggacg atacgtcaaa aatttacctg gaaacgcagg ccaagtcagc ttcacagttt
    35281 gcctcaccct ttgttaatct gaaaaaagag agtcatcaac agatgttaga ggatgagcta
    35341 ctacagaata aggcagtcta tattgtggtc aacaagcaaa aagcattacc aaaggcagtc
    35401 aagaaaatag tgacagctaa ttataaaatt gacagaaaga ttgatgttaa gggctttagc
    35461 ctatatcaga aaaaataaat aaaatcaata tattgtgttg gtataaaaaa acttaacaca
    35521 atatattgat ttttttgtgt ggcgtgatat aatagtcgag taaggagata ggacatgata
    35581 acattagaaa aagacaaagt tattgttcag ccagctatta aggttattaa aagagatgga
    35641 cgcttggtta attttgatgc aacaaagatc tacagtgcgc tgttaaaagc aagcatgaag
    35701 gtaacacgca tgtcaccgct cgttgaagca aagctagaag ctatttctga acgcgttatt
    35761 gcagaaatta tcgagcgatt tcctacaaat attaaaattt atgaaattca aaatattgtt
    35821 gagcatgagc tattagccgc taatgaatat gctattgcta aggaatacat caattataga
    35881 acccagcgtg actttgcccg ctcgcaggcg acagatatta atttttctat tgataagctc
    35941 attcacaagg atcagacagt agtcaatgag aatgccaata aggatagtga tgttttcaat
    36001 acccagcgcg atttgacagc tgggattgtt ggtaagtcta tcggtttgaa gctgctgcca
    36061 gcgcatgttg ctaatgccca ccaaaaaggt gatattcact accatgattt agattatagt
    36121 ccttatacgc caatgacaaa ctgttgtttg attgatttta agggaatgct ggcaaatggc
    36181 tttaaaattg ggaacgctga ggttgaaagt cctaagtcta ttcaaacagc aacagctcaa
    36241 atttcacaaa tcattgctaa tgtggcctcc agtcagtacg gtggctgtac agccgatcgt
    36301 attgatgagt ttttggcacc atatgctgag ctaaatttca aaaagcatat ggctgacgct
    36361 gaaaaatggg ttattgagga gctgcgggaa agttacgcct ttgaaaaaac aaaaaaagac
    36421 atttatgatg ccatgcagtc tctagagtat gagatcaaca cgttatttac ctcaaacggt
    36481 cagaccccct ttacctcatt gggatttggt ctagggacct cttggtttga gcgtgagatt
    36541 caaaaggcta ttttaacgat tagaattaat ggcttaggca gcgagcaccg tacggcaatc
    36601 ttccctaagc tcatctttac ggtcaagcgt gggctcaatt tagagccaga ctcaccaaac
    36661 tatgatatta agaccttagc cttggaatgt gccacaaagc gcatgtatcc agatatgtta
    36721 tcttatgata agattattga gctgacagga tcctttaagt caccaatggg ctgtcgctct
    36781 ttccttcaag gctggaagga tgaacagggg caagatgtta cctcagggcg tatgaacctt
    36841 ggggttgtaa ccatgaattt acctcgtatt gctatggaat caaatggcga tatggataaa
    36901 ttctgggagc tgtttaacga acgattacac atttgtaagg acgctcttgt ttatcgtgta
    36961 gagcgcgtta aggaggcaac gccagccaat gctcctattc tttaccaata tggagccttt
    37021 ggcaagcggc tagctaagac tggcaatgtt gatgagctct ttaacaatcg ccgcgcaact
    37081 gtatcattgg gttacattgg cttatatgag gtagcaaccg tattttacgg tgggcaatgg
    37141 gagcacaacc aagaggccaa agactttaca atcactattg ttaaggaaat gaaaaaggct
    37201 tgcgagactt ggtcagatga atatggctat catttctctg tttactcaac accatcagaa
    37261 agcttgacag atcgtttttg ccgcctagat actgacaaat ttggcgttgt tgctgatatt
    37321 acagataaag aatactatac taattcattc cactatgatg ttcgtaaaaa tccaacacct
    37381 tttgagaagc tagattttga aaaggcttat ccagcagccg gtgcttcagg tggctttatc
    37441 cattactgtg agtaccctgt tttgcagcaa aatcccaagg ccttggaagc tgtttgggac
    37501 tatgcttatg atcgtgtggg ctacctaggc acaaatacgc caattgataa gtgctatgaa
    37561 tgccattttg agggagattt caccccaaca gagcgaggct ttacttgtcc aaattgtgga
    37621 aacaatgacc ctaagacagt agatgtggtt aaaagaacct gtggttattt aggaaaccct
    37681 caggctcgtc caatggtcaa tggtcgtcat aaggaaatct ctgctcgtgt caagcacatg
    37741 aacggatcaa ccatcaagta tccggggata taagccttgg agaataatct cattacacct
    37801 atatcattgt aaaggattgc ttcatgcaag cagtccttta gttatcaaga caggtctgta
    37861 acaaagaaag ggagaaacat gggaaaatac cagttagatt ataagggaat gcagcaagta
    37921 gagaggtttc atgagaaaca ttctgttgca aaaacagaca aaaagtctcg agtacagcag
    37981 cttagagcac aatttttaga aaaagcaaag caatcaaaga aataatggca cactcagtaa
    38041 aggcggtgaa gaatgctaga tattggaatt gttgggttag gcgctatttc acaaaaggcc
    38101 tatttaccct atatgcgtca attaagagga atcaattggc atttatctac tagaaatgcg
    38161 ttagtccgcc aggaggtggg tcagcttttt ggttgcgcaa ggctttacag cactgtcaat
    38221 gagttacttg aggctaagtt agatggtgtg tttatccatg cagccactaa ggctcattta
    38281 gagctggcta gtttgttttt acaaaaagga attccagttt acatggataa gcctttgacg
    38341 gaggatttct ttagcacgca ggctctttat caattagcag ataagcacaa tacctttttg
    38401 atggcagact ttaatagacg ctttgcacct ggtgtcaaga agttgtcaac cctgtcaacc
    38461 aaacgtaaag ttgttgttga gaaaaatgat attaatagac caggtgacaa acagtttaag
    38521 ctttttgact tctttataca ccctttagat acagctttat ttttagttga taggaggctt
    38581 gttgcaggct attttcatta tcagctgact gataatgatt tgctaagtca ggttagtgta
    38641 accttaagga cagaacagac tattatttca gcagctatga atctacagtc aggtagcagg
    38701 cgtgaggtga tggaggttca gacacctaaa gagacctatc acctagaaaa tctagagacc
    38761 ttgcgagctt atcgaggggt tgatcaagag atcaagggat ttagtgcttg ggatactacc
    38821 ttatctaaac gaggctttga ggctattgtg gattcttttt tacaggctgt caaggatggt
    38881 gttaaccctg tcaagccaga gacaagtctg ttgagtcact ggatttgtca ccaaatttgt
    38941 caatctcatg aagctgatgg catattagat gtttctcttc ccttataaag gagtgataat
    39001 atgaagctac gaagacctaa aaagcaagat gaagcgtctg ttttagaaat gatggcagag
    39061 tttgaagact atcagtctcc tcatgatggt ggtttttgga acgctgagca ttttgattat
    39121 gaaaaatggt tggaatctaa tgctctgatg gaggctggct tagctatccc tgagaattgg
    39181 gtgcctgcca tacagctcgt tgcctttgct gatcaacagg ctattggatt tgtcaatgta
    39241 cgcttgagat taaacgaaca gctactggta aaaggtgggc atattggtta ttctgttaga
    39301 cctagccagc gtggaaaggg ctatgcaaag ctgatgctaa aggaagcctt gcagcttgct
    39361 cgtcaaaagg gcattcgtga ggttttagtg acttgtcatt gcagcaatag tgctagtcgg
    39421 tctgttattt tagctaatgg tggtcagctg aaggattgca ataagggtat tgaacgctat
    39481 tggataaaag cataagaggc aataatgaag gaaaactgtt ggaattctcc caaaccaaaa
    39541 gaatggacat cagaggcatt aagccaagga cgcgttattg attataaggc atttaatttt
    39601 gtagatgggg agggagtgcg aaactcactt tatgtttcag gctgcatgtt ccattgtaag
    39661 ggctgctata acgcagcaac ctggtctttt aaggcgggta ttccttatac gaaagagctt
    39721 gaggagcaaa ttatgactga tcttgcaaag ccctatgttc aaggtttgac acttttgggc
    39781 ggtgagccct ttttgaatac gggaatattg attcctttga ttaagcgtat cagaaaagag
    39841 ctgccagaaa aggatatttg gtcttggaca ggctatacct gggaggaaat gatggaagaa
    39901 acccaggata agctagagct gttaagcatg attgatattt tagttgatgg ccgctttgat
    39961 atcaccaaaa agaatctgat gctgcaattt cgtggatcca gtaatcagcg tatcatcgat
    40021 gttaaaaagt cactggctgc tggagaggtg gttatttggg ataagctaaa tgatggtgat
    40081 cagtcctttg agcaaatgag ccgcgatgat ttgatttagt agagacttat caacatcact
    40141 agacttgaaa gctaataatg aaagcatgat tttaggctcc tgtggtcttg cttaaccaat
    40201 ctaataaggg gttttcccca cattatcctc atacttatcc acaggttgtg aataacctgt
    40261 tggtttgtgg ataaaaaaga gaattaaggg gttctttaat tctctaggcc tgaaaaaggg
    40321 ttctttttga tgttttttct taaaagaaag agaggcaagt gacctctctt gaaatagtat
    40381 acttaggctt taagcctagc tttcaatatc tctgaatgtc tgattttctt aggagtcagg
    40441 cattttttaa tggcgatggg aagtacggct tgtgggtcgc tttgtgtgct aagaggcttt
    40501 ctgagctgct atatgtcaat gattggtgat gtgacagctg aggcttgttc acattctgaa
    40561 agcactgatg tttttcctag ctttcttttt tgatgtagta gtaattagtt tcggttgata
    40621 gctcctcatt atagcaaaag ccagcaaagc tcagctgctt aagtgcttcc ttggtttgga
    40681 cattgttttc tagacaggct gttagaaagg ctcctcgagc tttttttgaa atggttgaat
    40741 gcgtcttgag ctgtcctgat ctttcctcca taaatttggg acttatccac agtttttgat
    40801 attcctttga aaaaacatct ctaaactcgt tggataacag agaaatgatt tgcttgtgat
    40861 ctttagcaaa ctgatcgtag atagggcgcc aataatgctt aaggctttgc ccattgatgg
    40921 ttactttagt gtgaaaatca tgccggtgct ctgcgatttt ctcatcagta gggataatgc
    40981 cataaaaaga cgaggtaatg tagacctgct ttgagaggta gtcttgctgg tctttagaga
    41041 gattgtcgcg cttgagatga cggtacatga gcccattaaa gagctgataa gcaggataag
    41101 cagaactctg cccttgagct atggccttta gtctcttggc ttccttgctt gctgcttcta
    41161 tacggatgct gtaggccctt gctagctcct ctagggatag ttcagccata gcctctaata
    41221 tgggcaggct tttttgggga agctgatgtg gatagcaagg tggaactggt ttcatttctt
    41281 tagctgttgg aattaaaaaa gttaacataa gtttattgta gtaaaggcgg caaccttctg
    41341 tcaagagtgg gatacatttg gtggttatgt catatgaaac taatttttat attttttaca
    41401 ttttgattag tttttaaaaa tatagtgatt tagtgttgca taacctctct aagtatgtta
    41461 atatatactc aagtctgttt gataaacaga agctcaggtc aagtgagtgt tccacttaca
    41521 ataacgcagt tgatgatggg gagactcaga ctcagactca gactcagagt caaggaaaag
    41581 aaatatagtc ttgtaggatt acctacaggg cttttttcta ttttgaattg agagatcaat
    41641 ataaggtgat gtgctgtttt ttattacctt aaacatttgg atattggcta ttgacaaaaa
    41701 gtgtaaagga aactatacta tatgtgtaaa gttaacttga catattggag gaaccatgga
    41761 aaatcggata caagaactcc gtaagtcacg agggattagt caagctgatt tggcagatat
    41821 gatgtgtgtc actaggcaaa ccattatctc cttagagaaa ggacgctata atgcgtcatt
    41881 agagctggcc tataaattag cgacattttt caatctgact atagaagacg ttttcttgtt
    41941 tgaagagaag ggagaatgag atgatattta gtgatttaag cgtcctgctg actcaaaaaa
    42001 gccagctagc ctatgccaaa aggctgaagt atatgggctt tttcgctctc tgtttaggcg
    42061 gtttgttttt gttgctggcc tttgacgtga gactgacgag ctttgctcag ggaatgctgg
    42121 tagggcttgg tagtggtagc ttattattag gtgttcgtgc tttttcagat tgcctttaat
    42181 cctcaaaggc tgagagcctc ttatattaag gcttatgatg agcgtcatca ggtagttatc
    42241 aagctagctg ctgtatcaac cttaatctta ttagtggtgt tgattattgg ctgtttgtgc
    42301 ttgaatgttt tttggagttt ggtttttggc tttagagtat ttttagagat ttgtctgtat
    42361 acgatcttgc ttggtttttt aggcatcaag ctattgttag agcatatgat ttaggaggct
    42421 tcaatggaaa caaaacattc agcagtaaag gtcatcatca gtaaattaaa atggtttggc
    42481 ttagctcttc ttgtgtttat gcttgagcag gctccaacat ttttgataac aaaagaacag
    42541 ccaatgtggc agacacttct tcttgtggtc atttttcttt tgattagtgg aggtacttat
    42601 tacctagctg tgaagcttca cattgtggga gatcaagcta ttcctaagaa tgactatcgg
    42661 gcactttgga ttggtttggg agtggtagct gtctttgttg tcaagatgat tggtggtatt
    42721 ctgttgtttt tggagcatgg tccgggagcc aatacggtca atcaagctgc cttagaacag
    42781 gcaggcttat ctccgattct tatggttacg ctagttgcta ttgtggcacc aattgtggaa
    42841 gaaattgctt ttcgagggct gctttatggg aagctctttg gtgcagagtc ttatctgggc
    42901 ttgattttta gcagtatcat gtttggcttg attcatgtgc caacagattt tggcagttgg
    42961 tttatctatg gcggtatggg gctggtgtta ggctttgttt tccataaaac aaagaaggtc
    43021 gaatacacga tattgattca ttttttgaat aatgcactag ctgttcttat catgcttttg
    43081 ctgccttatc ttcagtagta ctgcttgagt aatgaagggg gtaatgaatg aaaaatgatc
    43141 gttggattga caaaaaatat caacgttggg agaaagtgta taagagactt ggtcattctt
    43201 tactgacaat cggtgtgttg gtagggactt atgggatttt tttgattatt caagggaatc
    43261 atcaaacggg ctttctcctt tttatcctgg ggcctatact attgattgcg tcatgtcttt
    43321 gctattatgt gtttacagag ccaacgtctt tacgagaata tctgattaat agctatgatg
    43381 agcgtaaccg agctattcgt cagaaagcac aggcctactg cttttgtcta tttgcttttc
    43441 tctttttgat gcttgcgata ttctttccaa atatgacgat caaggagctt tttgggtata
    43501 atcttccgtt gattgttttc aatctgtatg tcatgattag agcctgggtt agtaaacaca
    43561 tgtaggtcat gttaacacaa aggagtctag agcaagggct ttgaatgaaa ctatttttct
    43621 aaaaacgcaa aaaatcgcgt gcagtaacag attaggccat gttactgcat gcgattttgt
    43681 tgtttcaaac gtgagctcag aatgacatat cctttttaga aagaataggt atttagggct
    43741 gtcttgagct agtcttaggt aatgagcttg gagctcattg gtgatggtta ggataggtct
    43801 ttagcttttt tgatcgttgt gtcaatggca gagcagacag aatgtgtcag gcctgttttt
    43861 tcaagatcca tcaagcctgc aatggttgtg ccgccgggac tgcagatctt atcaatcaaa
    43921 tcatggggac tatctgtgct gactagcagg ttcttggcgc tagctaggac agtttgacta
    43981 acgatactaa gggccttgtc tttaggcagt ccatttttga ctccggcctt tgccatagct
    44041 tcgatgaaaa ggtaaagata agcaggactt gaccctgcta gagcagtaaa ggtatcaaaa
    44101 tccttttcag ctatttcaaa ggttgttcca aagctgttgg ttagctcttt agcagtagct
    44161 aataaatcag cagttactaa gtcattacca gtcaaagcag tggtgctttg gagaatttga
    44221 gcattcatat ttggcatgat acgtaggagt ggcaaatgag agcttgttaa ttgagctagt
    44281 ctgtctaagg aaataccagc agccattgac atgataggct gtttgaactg tagagggcta
    44341 agaacagtct caaagagctg tggcttgatc cctagaatga tgaagtcaac ctgatcgatc
    44401 agctcttggt gagattgggc gtagcttagg tgcaattggc cagcaatttc tttagagcga
    44461 gctaaggatg agcctgagat gattagctcg tgtggtgtgt gtgttaggcc ttgaatgata
    44521 gcagttgcca ttttgccaac accgataaat ccaattttca taataatgtt cctaaaaatg
    44581 aataaaggct caataggcta gagtgctcat tgaaccttag attcgcattt tagccttatc
    44641 cttcctagta tttcttgatt aaatcaactg ttgagcggtc aagctttttg acaatggctt
    44701 gcaaaaaggc ctgtgcttct acgaaatcat ctaaggcgta caagctctga tgtgagtgaa
    44761 tgtagcgagc gcagacaccg attgtggttg aagggatacc gccattttta aggtgagcag
    44821 caccggcgtc tgtaccgcct ttaccacaat aatattggaa ggcaacccca gcctcctcag
    44881 cggtggttaa taggaagtct cgcatgttct taagcatgat gtgtccggga tcgtaaaagc
    44941 gtagaagggt tccatcacca atatgggcag gattgccata aatatcacca gcaggtgagc
    45001 aatcaacagc aaagaaaagc tcaggatcaa atgtagtggc tgacacatgg gcaccacgaa
    45061 gcccgacttc ttcttggaca tttgctccag caataagggt gttgtgaagt gtctggtctt
    45121 ttagggcttc tagcagctca gtgaccatga gaacaccata gcggttgtcc caggcctttg
    45181 agatgatatt ctttttattg gcagttaaaa tggtttcaga ctgcggtaca ataatatctc
    45241 ctggtgtgat gccaaagctt tcggcttcag ttttgtctgt aaagccacca tcaaaaacaa
    45301 tatctgaaac cgctggcaga ctagcagcac catttgcccc gcgcagaaaa tggggaggaa
    45361 ctgagcctga aataacagga atggcttggc cagcgcgagt gtataaggta aagcgctgtg
    45421 agctaacaac tagtggattc cagccgccaa tttcaacaac ccgcagtgtt ccatcagctt
    45481 taatctcgct caccataaag ccaacctcgt ccatgtgagc cgcaacaaga atgcgaggag
    45541 cttgatccgc cttgctttct tttatcccaa atatgccgcc aagtccatca acctccactc
    45601 ggtcaacaag cggcgtgatc ttagcgcgta agtaatcccg aacagtgtgc tcgtagccgg
    45661 cgatgccgtc taattcagta acttctttaa tttttgaaaa taaatcaatc atttgtatac
    45721 tccatttgtc atgtaagatt aaaggtatca cgtctgcctc tattctatca ttttttagtg
    45781 aagaatggga aacagcttga gcataggaaa agagtttggg agattaggtg tgtctttctt
    45841 gcttgataag ctgcttatta tcagtttgat tcagatgaga taactgctgg tattgatgga
    45901 atgaaacagc tatgcacaac agccttgaca aggatcgaca ggcctgagct gtcttatgct
    45961 atcaattgca cttaggtaga gcagtagcct gatattgatg tgattagttg ctcttgtcag
    46021 gtggtttatt agtatttcct aaagtgtcag ctagtcttgg ctgagattgt tagcttttgc
    46081 tctagcctat tattcccttt ttgtgataaa atgaaaggta tgaatggaaa aaagacacgt
    46141 attgtttcag gattaattgg actgggtctg ctagccggct tgggattgag gcttaaggaa
    46201 gtctatcaag aaagagagcg tcagagagta ttggttgaat tgcgcgcctt tttctcagcc
    46261 ttaggagaga ttgaggtctt gtacatcaac tcctttagct caaagcgtga tgatgtcact
    46321 ggtggccttg tcatgacaga tggtaagacc tatacttacc attaccacaa aggaagtatt
    46381 gattttaaag aggatttgac atgattattc caacatctaa ggaagaactt gctaggctaa
    46441 ttgagacaga gcctaggctg gttttgtttt ttacagcaga ttggtgtccg gattgccagt
    46501 atatctatcc tgtaatgcct gagctagagg ctgaaaaccc ggatatgacc tttgtccgcc
    46561 ttgatcgcga tgattttatc gatttagcgc aggattggca aatttttggc attccaagct
    46621 ttcttgttat ggaaaagggg caggagaagg gccgtttggt caatagatta cgaaaaacaa
    46681 aggctgagat tagtgacttt ctagcagcct atcactaaga ggagaaaatg agatgatttt
    46741 tgcatataat aaagagcagg tcggtgatgt tttgatggtg atactagagg ataaaaaaga
    46801 catcaagcga caggttgagc gtaaggggag agtagcgcgt gtttttgcag aagagacagg
    46861 gcaaaccctt gcttggaata tttttgaggc gtcagcctta atcgctgttg agggaaatgg
    46921 gcaggttttc ttgtctgagg aggagttagc gattttaaat gcggagcttg ctcaagaagg
    46981 gtttactgaa cgattagagg ctagcccagc ccctgttttt gttgtggggc aaatcattga
    47041 gatgattcct cacccagata gtgatcattt gaatatctgt caggtacaga ttgctcctga
    47101 taaggctgtg caaatcgttg caggagcacc taatgctgct gttgggttaa aaacaattgt
    47161 tgccttgcca ggtgctatga tgccaagtgg cagccttatt tttccaggaa agcttcgtgg
    47221 gaaggaaagc tttggtatga tgtgttctcc acgcgaattg gccttgccaa atgctccaca
    47281 aaagcgtggt attattgagc ttggtgatgc tgcagcggtt ggtgaagcct ttgatcctgc
    47341 taagcattgg cagagctagc aggacttgat cagcattaaa atggtgttta gtccttcttt
    47401 tgcttggtga aaagcctttg gaccttgagc catgcagtgc tttttgctgg tctgtgactg
    47461 tctttagctt caggatcgaa gcattagagt agctgcttaa cttattgtca gcgctgttga
    47521 ttgcagtagc gctatgcttg tgacaagtga aggcaaagcc tatcaatgcc cttggctagg
    47581 gctaaaaatt gtctttagag tcacttttga ggtgagtagc tcgctaattt cggtattgaa
    47641 cggtgcttag gtaccgtttt tttaagcttt gctgagtgtg acatgctgaa aaaaggccat
    47701 gtctttatat ggcttttggt cacagatggc taattcaatc gtccgcaaca cttccagcca
    47761 atcaggctta gctttaacct catttggttg aagtccgtag catgtccgca gtccacgata
    47821 gccttggagc ttcaaatcgg tctttctgag taagtcatca atactgtagg tctgacctgc
    47881 tgcaaaggat aaactttcaa aggcttgtcc atttagcaca ttaagtgcct tgtcatagtc
    47941 gtgttcaaaa ataacagagt ggagaacttt tccgacttga ttgtgcttga tgagtgatag
    48001 ctgcccttta ggcttcaata gacgttccat ctgagctagg tagatcgcat gctcttttgg
    48061 ggcgatatat tctaagacat tgtggcatat gatcatatca aaggcttgat caggcagttt
    48121 ttctagcgct tctaatgaac cttttatttt atgaatgctt tcttgctttt gggcaaataa
    48181 taggtcagga tttggctcaa ttgcagttac ttcattctgg acggctaatg cctctgctgt
    48241 gatgcaaaag cctgctccga aatctaaaat agtcttgcct gctatggggc ctaattgggc
    48301 aaagatcaaa tcatacatga gctttcccca gggccttgtg agcatgtctt gataggcttt
    48361 aagattaata gtcattatct agttttcctt tctttagctg ctgtgagcta ttggcaggat
    48421 ttctaaactt cacagcttgt ccttatttta ccatgtttta cgaataataa gataaggagg
    48481 tatgacatgt acaataaagt aatcttgata ggccgtttag tggccaagcc agaattaaac
    48541 aagacattaa cggataagca ggtcgttcga tttaccttag cagttaatcg tcggtttaag
    48601 acgacgactg gtgagcgtga ggtggatttt atcaatgctg ttgcttgggg aggtttggct
    48661 gaaaccttgg cttcctatgc tagcaagggg agtctgctgt cacttgatgg cgagcttcgc
    48721 acacgaaaat atgacaaggc gggtcagact cattttgtga cagaggtttt gtgtcattct
    48781 tttcaattgc tggaaagtcg agcgcaacga gctatacgtg aaaacaacgc tgctaatgat
    48841 ttgattgatt tggctttaga ggaggaaaag cttccctttt aaagacagct gctagcttac
    48901 tgtcgctaag ggagtcagac actagcattg tgtatgctag agatctcaac ataatctaaa
    48961 aaatgacaac gattctaaaa aaaatcttga cacgtcttag aaaaaggttt acaatgtatg
    49021 acaattaaaa tgaaagaaaa caggaggtgc tggtatggta gcagttagca cagctcagac
    49081 gatgactaag cgttattact ttagcttctt tagatagtgt ttgtagacat gagcgcatgg
    49141 atacaaacac actgaacgtt atgtttgtat ctatggggct aagggctatt tgagttgttt
    49201 gtccacatag atgatatctc ttctaagtgg acaccataca gcatgtattt tgttatctca
    49261 tgatacctgt ataggaccat ttagattatc tagatggtct tatttttatg caagaaagag
    49321 gaaatgacat gagatttaaa cagttatcct taacagcctt tatagggctt ttggcaatgc
    49381 tgctaacggc ttgtcgacaa gaaaccaacc aaacacatca agctgctaga gttgggatta
    49441 ttcaatatgc tgagcactca gccctagatg ctgcgcgtga gggttttatt gaggcgcttg
    49501 agcagggcgg ctttagagag gggaagaacc tgaccattac aaccaaaaat gcacagggtg
    49561 atcaggctaa cctgcaaaca atggtggagc agctggcggg taagaacgat ttgcagcttg
    49621 cgatcgcaac gccggcagcg caggcgcttt taaatatgga ctcagagaca ccagctgtat
    49681 ttacagcggt aacagatcct gtctcagcag gtctggttga tacattagct aagcctggtg
    49741 ggaatatgac aggctctaca gatgcgactg atgttgagaa tcagattgat ttgttgacca
    49801 aggcgctgcc tcaagctagg acagttggga ttttctacaa ttcaagcgag gtgaattcgg
    49861 agatacaggc taagaaggcc aagagggagc ttgagaaaaa aggcttaaag gtccttatga
    49921 aaaccgtaac cactactaat gatgtgcagc aggttatgac aagcttggct agtcaggttg
    49981 acgctgttta cctgccaaca gataatacgg ttgcctcaac agctactact attggggata
    50041 ttttaaagga ggccaaaatt ccttcaatgg gaagcgatgc tgcttacctg agtgctgttt
    50101 tgttcacctc aggtgttgat taccatgcta ttggcatgca ggctggtcag caggcggtag
    50161 atattttaaa gggtaaaaaa ccagcaagca ttcaggttgc taagcctcaa aaggcaagca
    50221 ttgctgttaa tgatgatatg gcaagacttc tgggcattga ccccgaggtg atcaaggctc
    50281 ttgcaagtaa cggagccaac tagcgtttta ggaggaaggt atgaaaaaag gaagctattt
    50341 aatactgtta gtgcttgcag gcttcgtttt ggtggcttgt cgttcgacag ctagtcctcg
    50401 taaggttaac caatctcatg ttaacatcgg tattttacaa tacatggaac atgattcgct
    50461 gacggcagct cgtcgaggct ttgaagcgca attaaaggca gcgggctata ctaagggaga
    50521 caagctgagc cttcattatc aaaatgcaca gggcgaccaa gctaatttac agacgatttc
    50581 agagcagcta gtgaagcaaa atgatttgat cttggcgatt gcgacaccgg cagcgcaagc
    50641 cttagcgacc gtctcatcag atagaccaat tgtttttaca gcagtaacag atcctatctc
    50701 agcaggctta gtggatagga tcaaaaagcc tggtggcttg ataacaggaa caagtgacca
    50761 ggcgccgatt gcaaagcaaa ttgacttgtt agcccaagcc ttgccagagg ccaaaactat
    50821 tggcatttta tacacagcta gtgaacgtaa tgctgaggtg caggtaaagg aagctgaaac
    50881 gctactgacc aaggttggtt atagggttat taaaaaggga attgccactt caaatgatgt
    50941 gcaagatact gctgcaagct tgatgagagc agtagacgcg ctttttgtac cgacagataa
    51001 taccgttgct tcaaccatga caatgctggg tgagctgtca ttggctaata aggttccaat
    51061 tattggtggc tcaacggata tggttgatgc aggtgggctc ttgacctatg gtatcgacta
    51121 cgagagcctt ggtagacagg ctggagaaat ggccattaag attttaagag gacaggatcc
    51181 agcaagccta gcagtggagt acccaaaaac agtcaagcta catatcaatc aagcaatggc
    51241 agacaagcta gcgattgata cttccacatt atcagttgac taaattgcta ggttaaaggc
    51301 taaatgactg atctctagcc agctggctaa atgacaaagt cttaaccagt tagcttagct
    51361 tactattaac gattcatatg acaaaaaagg agaaatcatg tcactcattt tatcgagctt
    51421 atcacagggc ttattgtggt ctattatggc aattggtgtt tacctgacat ttcgtatttt
    51481 agatattgcc gatttaactg cagaaggttc ctatccgctt ggggcagcta tttgtgcagc
    51541 gggtattgta tcaggtgttt ctcccttgct ggctacgttt ttagctttta ttggaggctt
    51601 gctggcaggc cttgtctcag gattagttca caccaaatta aaaataccag ccttactaac
    51661 aggaattatc actctgacag gcttgtattc tgtgaatcta aaggtgctag gaagagccaa
    51721 tgtggcttta ttacgtcaaa gaactttagt tacccagctc tatgatctag gctttaccaa
    51781 gcttgcagcg gtgctaatta tgggctttgt ctttgtgacc attgtgattt ttttattagc
    51841 cctgctgatg aaaactcagc ttggcctagc tctgcgatcg accggagaca ataatccaat
    51901 gagtgaagcc aatggtatca aaacagatca gatgaaaatc atggggtata tgctatctaa
    51961 cggtttgatt gccctatgtg gtgccttgct ttgtcagaat aatggctatg cagatttaaa
    52021 tgctggtgtt gggacaattg ttattgggct ggcttcgatt atcattgctg aggtgatgat
    52081 taggcagcta agcattggct ggcgcttagc ttccattgtt ttaggctcta ttgtttatcg
    52141 cttaattatt ctagctatcc tagccattcc cggtatggat gcagatttgg ttaagctttt
    52201 ttcagccatg ctattggcag ctgttctttt tgtgccagaa ttacagcaaa ggcttcgcct
    52261 tcgaaaaaca agtttaggat aggagaaatc atgtcagcaa tattatcaat taaggctatt
    52321 cacaaaacat ttgaagcagg tacgattaac gaaaatcatg tcttgagagg cttatctttg
    52381 gacattgagg agggggattt tatctcggtt atcggtggga atggcgctgg aaaatccaca
    52441 ttaatgaata ctctagcagg cactctggct tttgatcagg gcgatattct tttagaggga
    52501 aaatcaatca agcatttatc agccgctaag cgtgccaagg acatcagtcg agtgtttcaa
    52561 gaccctaaga tgggaaccgc ttcacgcttg accattgagg aaaatatggc tattgcttac
    52621 cgccgaggga aatcaagggg gctaggctgg ggcgttaaag aaagagagcg ccagatctat
    52681 cgtcaggcct tgcaggaatt aggcctaaat ctggaaaacc gtcttaaggc cgagacacag
    52741 tttttatcag gagggcaaag acaagccttg accctgttaa tggcttcctt agcaaagcct
    52801 aaggtcttgt tgctagatga gcataccgca gctcttgatc ctaagaccag tacaatggta
    52861 atggctttga caaagcagct tgttgagaca catggcttga caaccctgat gattacccat
    52921 aatttggaaa atgctattgc ttatggtaat cgtctggtca tgctccatca aggtaatatt
    52981 gtggtggata ttaagagaga agagaaggcc aagctgacgg ttgaccactt gatggcactc
    53041 tttcaccaaa atagtggtca tacgctcctt gatgatgcac ttgttttggg ataggctagg
    53101 tgagggttag ctctgttttc aaatagcagc cataatgaaa aggcttaaag ccaacgcttc
    53161 tagaaacgct agctcaagcc ttgttataat acttaggaga tttttctaag agtgataaag
    53221 ccatgatgac gtctattgta gtcaaaggat ttgtttcgga tgcgataagc ctcattttcc
    53281 acaatttcaa ttgccttatt cagctgctga atggtaatcg cctcatcaat ctcatgaaaa
    53341 gcagtgctat aataatcctc actaacacgt tgattgcggt ctttataggt atttttatgc
    53401 tctgttaaaa tggccttagc ctcagcacgt tttgcaatgg tatctataat accttgacca
    53461 tatgctctag cctcttgaag gattgacagc atattgtcta gagaatatgc gtttgctaag
    53521 cggctgacaa agctatcagc gacctcagga cttaaattaa taccatctaa gtgataaatc
    53581 atctctgggt gtagctttag gtaatactgc aattcgcgga acaaaagcgc tggaattttc
    53641 gacgaatccc tatatggatt gagctgaatc tcctgactat gtagcctatt gataaaatcg
    53701 tccttgaact gcttaatagc atcgtagtct gatttttcta gctctgcttt aatattggct
    53761 agaatctggg cgtctgaata acgacgatag cttgatagtg aagcagcagg cctactagta
    53821 ttggaatttc gagaagcttc tgctcttcta gtctctttgc ttggtgtttg ctgcttattt
    53881 gactgagtct cctgctcggt tagtcgtagc tcagggtgta aacgactaat attgttaaga
    53941 aattggttaa cctcatattc tgatgaaaac tttagcctag gtctggcctt gaccttctca
    54001 atagccttgt caataatcct tttcccgtac cttttgagat tactgtcaga ctggatcaaa
    54061 taaagattaa catgtaagtg atcttgacta tccgccttag ataagctgtt accaaggcca
    54121 aggcttccta agagcgtagc tagtaacagc aggtgtttta ctagactacg ctgaacaata
    54181 ttgtgacgac taagcataag ttattttccc attctattgt aatataccag aaaatgttat
    54241 caaaataaag ataagatgtc aatgtcatta atggtggtta atctttaatt aatggtcgtt
    54301 aatctagtat atcagagagc tagcttaggc tggcagtggt cattctgtgc gtcttggtac
    54361 gaaatgccca agcagatgca gctcactaga atgatcaata gcctcaacac aaagcccctt
    54421 acagcttgac acaagctgta aggggctttg ttgtattaac agataactca aatccttgct
    54481 ttttataata aatctaaggt ttttagcttg tcatcaatca tgtgcagaac ggttgccaaa
    54541 tcctctgggt tttgcacgaa atcaagcttg tttccatcaa tcttcatctt aggtgaaacg
    54601 tcatattgct cataccagct tgggtattca ccatgtacct gatggtaata ggcttctaag
    54661 tcaggattgt cgtcaacctg ctcaaaacgt ctgccgcgct tttcaatgcg ctctagcatc
    54721 ttctcaaagg agacatcaat ataaatcagc agatcaggcc gtttttaagg cattccttca
    54781 agctcctcta gcatattggc taagagctct tggtaaattt caagctctgt cttggtaaca
    54841 tttccatttt tatagttaag tgtcaagaag aactcatctt caaagattga gcggtcaaga
    54901 atattattgt ctgcctggta ggcttcttta atagatttga agcgcttgtt caaaaagaaa
    54961 atttgtagta aaaaggcata ttttttaggg tcttggtaat acagatcaag aacaggattg
    55021 ttatcaacag cctcgtaaaa tacctctgtt cctaaatgct cacccagtgc agcagcaagg
    55081 gaactcttgc ctgcgccgat tgttccagct aatacaatca acatgtttct ccttctatgt
    55141 agtcttagtg tatttgtgca aaaatcgttt caacctcagc taaggtttta gcgcgtgaaa
    55201 cggcactgcg aattttggca gcgcctgctg tccctcgcag gtaatgaggg gctaacccac
    55261 gaaattcacg aacagcaata gcttctccct tgagcctgat gaggcgcttg agatggtctt
    55321 tagcaatatc tagcttttta gcaaagggca gctctggcaa aacctctcct gtctcaaaga
    55381 agtgattaat ttgggtgaag agataagggt tgttcatagc tgcacggcca atcatgaccg
    55441 catctacacc aatctcctca atcatgaacc tagcgtcctg aacagttctg acatctccat
    55501 ttccaataaa tggaatcctg gtaatagctc ttgagacgcg tgcaagggtt tcatggtcac
    55561 aggtgccagt atacatctgc tcacgagtac ggccatgcat ggcaagagct gacacaccag
    55621 cagcttcagc agccaaggca ttctcaacag ctagtgagct gtctgcccag ccggtacgca
    55681 ttttgacagt cagtggaatg tctaaaacag aggttacctc ctgaatgata tggtaaatct
    55741 tatcaggatc gcgaagccac ttggcacctg cttcattttt aaccaccttg ttaacaggac
    55801 agcccatatt gatgtcaaca atgtcagcct tggtatggct ctggataaaa tcagccgcac
    55861 gctttagtcc ttcagcgtca ccgccaaata gttggattga catggggtgc tcattgtcat
    55921 caatatgaag catatgcagg gttttttcgt tattatagag aagtcccttt tcagaaatca
    55981 tttccatgac aacaaggcct gcaccaaatt ccttggcaat cgtgcgaaag gccgaattgg
    56041 tcacaccagc cataggtgca agcactgtac ggtgagggat ttccacatga ccaatcctaa
    56101 agggtgagtt aagccttgtc attgatcagc acctccaaat cagtttggtc aaattggtac
    56161 ttggtgccac aaaattggca aacaatttca gcccccttat cctcgtttag cattgtcaac
    56221 aggtcagctt tagggaggct cattagggct gacgcaaagc gctctcttga gcagtcacac
    56281 tgaaagctca gctgctcttc agctaatcgc ttgtaaggct cttcaccata aatagctgct
    56341 aacagagcgt ctatatgatt ttccgacgct agaagggttg aaatcgcagg catttcctga
    56401 atgcgcttct catagtggct aatctcttcg acagaagctc caggcagcac ctgcagcata
    56461 aagccgccag caaccttgac cttgtcctct tgatctagaa gcacattaag gccgacagca
    56521 gatggtgtct gctcagactc tgtcaagtag taggccagat cctcaccaat ctcaccggta
    56581 atcaagggtg ttgtagaggt gtagggattg cctgttccat agtccgtaat tgtcacaaag
    56641 tgtccctgtc ccataaaagg accaaccagt acttctccag ttgctgtttt tttgatatca
    56701 acaccgggat tttgaatata gcccttgaca tgcccttttg tgtcagcaac agaaataata
    56761 tgcccaaagg aggaatcgcc aataaccttg acagtaacct tactatctcc tttttggttg
    56821 gcagctagaa tctgattggc aatcaaggta cgaccaagtg caaccgttga agatgataag
    56881 gtatgatgcc tttcctgagc atatcgaaca gtttcggtgc aatccaaaac ataggccctg
    56941 aaggcaccgg aggcagaaat tgttttaatt agtttatcca taatttctat tatagcataa
    57001 tgaacaaggc ttgtgctggt tgctttagag gaaagctgct tgaaaataga gaaacactat
    57061 ttggttaata atagcagctc tataaagcca cttaaaaaca gagcagtgct aacaaatggt
    57121 agtattcttg tccttagcac gcagtaagct aatcacctaa gtcagtacaa tcaaacaagc
    57181 atcaaaaaac agctccgata ggttgattaa aggaagaaat gataaaagag ttatttcgta
    57241 atgctttgct gataatgagc aaggtaatca tgtggtgtcg tatcagtgta ctttttgaag
    57301 gttttcaaaa aatgggtggt atcgtagaaa taaaggagct tagccacttc tccagctggt
    57361 actcctcttc gtaaaagtag cttggcttct tgtacttttt ccttcaaaat ataggtctgc
    57421 aacgaaatag aagaatacat tttaaaaaca gctcgtaaat gtgactctga gatataaaga
    57481 tgcttagcaa tatctgatac ctttaatttt gaataaaggt gcttatcgac gtaatataaa
    57541 atactattat aaatttgctg cttatcagaa acacttttgt tagtcaatga ttctgagagg
    57601 ctaataatag cagctgctct tatttgaagc accttaagga gatctgtagc tttttcagtt
    57661 aggttcataa aatgcttaat gcgctcgtag tttttggcaa catcagtatt ttcagtaaag
    57721 cttagttcaa gcagcttaat aaaataaata atagaaagat ttttttcagc tcttaatgcg
    57781 ggaatagaag aggagacgac atctgatgaa gggatacaat tgatttcgtg ctttaatagc
    57841 tctgtattac ccagcttgac taaatcaata atatgattca aataatttaa gacagctggc
    57901 acatgaaatg acggggtatt ttccaattcg agattagcta taatatgagg atcctcccag
    57961 attagctggg cttcctccag taaatcatta atgctttgct ggcagctcat ttcaaagttg
    58021 gtgtcaaaaa aggcatcaac agctatcaaa aggcttcgaa tatgagaagc aggaaaatga
    58081 ggaatggtag agatatagcc aactagctct ttttttgact tatcaggata gcgcttcaag
    58141 aagctatcgg ctaattcctc cttatagcta tcctgaaaga aagaggtgta aaaaggccca
    58201 atgaaaataa acttgtcacc aataggaaac attagagagg attcctcaag cgttccctca
    58261 taacaagtga gctcagtatt actaggaata tctaatgttt taattaattc atagtagggg
    58321 aatcgacgct cctcgtcatc ataagcctga aggagctcaa gattttgaga aagcactaaa
    58381 acaggtaatt gtgataggtt atgcaa
//
LOCUS       DARYLJ010000006        58146 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYLJ010000006 DARYLJ010000000
VERSION     DARYLJ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58146
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..793
                     /locus_tag="TU746_000318"
     CDS             <1..793
                     /locus_tag="TU746_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0890704.1"
                     /translation="RLKECYPQLSFAEPMISSTMALESIKLSARVSLFKTIKNVSAIK
                     KSFYPCNMEELDQPTGYLLYRTHLARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEE
                     IGQDILIHQEGETTQLDILVENMGRVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHF
                     PLDFQELDWIDFSAGWTDEVPGFYAYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRF
                     WKVGPTLSLYIPKGLLKQGQNRLLIFETEGQFSESIRLTKEPIYK"
     gene            811..1296
                     /locus_tag="TU746_000319"
     CDS             811..1296
                     /locus_tag="TU746_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0890705.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            1342..2223
                     /locus_tag="TU746_000320"
     CDS             1342..2223
                     /locus_tag="TU746_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0890706.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            2210..3028
                     /locus_tag="TU746_000321"
     CDS             2210..3028
                     /locus_tag="TU746_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL0890707.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            3032..3436
                     /locus_tag="TU746_000322"
     CDS             3032..3436
                     /locus_tag="TU746_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL0890708.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(3540..3800)
                     /locus_tag="TU746_000323"
     CDS             complement(3540..3800)
                     /locus_tag="TU746_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL0890709.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(3925..4857)
                     /locus_tag="TU746_000324"
     CDS             complement(3925..4857)
                     /locus_tag="TU746_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL0890710.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(4867..5295)
                     /locus_tag="TU746_000325"
     CDS             complement(4867..5295)
                     /locus_tag="TU746_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0890711.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            5553..6578
                     /locus_tag="TU746_000326"
     CDS             5553..6578
                     /locus_tag="TU746_000326"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL0890712.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            6639..7085
                     /locus_tag="TU746_000327"
     CDS             6639..7085
                     /locus_tag="TU746_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL0890713.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            7414..7707
                     /locus_tag="TU746_000328"
     CDS             7414..7707
                     /locus_tag="TU746_000328"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL0890714.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            7688..8920
                     /locus_tag="TU746_000329"
     CDS             7688..8920
                     /locus_tag="TU746_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL0890715.1"
                     /translation="MMMKPIKNNQDISIGDNVYLAFAALLVGVVVGVIDTVFGQGLLL
                     LSAVRDAHLIYLLPCLALAGLVIVFLYEQYGQIAKQGMGLVFDVGHGEKTRLPLVLIP
                     LIILSTWLTHLCGGSAGREGVAVQIGATVSHFFGRLRHLKDKSQLFLVMGMAAGFAGL
                     FQTPMTAVVFALEVLLLGNISYLALLPSLIAAFTASWTSHCLGLEKFSVPIAKALKIT
                     PITFGKLVLLGLIFGLAGNLFASLLARAKPYIAARLPNPYYRVLLVGGFLSLSLLLCH
                     YGRYSGLGTNLITAAFSHQPIANYDWLLKLLFTIITLSAGFQGGEVTPLFAIGAALGI
                     VLAPWLGLPAQLAAALGYAAVFGSATNTFLAPIFVGLEVFGATNATAYFIVIAFAYMV
                     SRRHSIYTKQRVTTSIAS"
     gene            9066..9413
                     /gene="rplS"
                     /locus_tag="TU746_000330"
     CDS             9066..9413
                     /gene="rplS"
                     /locus_tag="TU746_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL0890716.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            9928..9999
                     /locus_tag="TU746_000331"
     tRNA            9928..9999
                     /locus_tag="TU746_000331"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9961..9963,aa:Arg,seq:cct)
     gene            complement(10123..10926)
                     /locus_tag="TU746_000332"
     CDS             complement(10123..10926)
                     /locus_tag="TU746_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0890717.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
     gene            11554..11769
                     /locus_tag="TU746_000333"
     CDS             11554..11769
                     /locus_tag="TU746_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0890718.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            11766..12542
                     /locus_tag="TU746_000334"
     CDS             11766..12542
                     /locus_tag="TU746_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL0890719.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVMGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(12611..13867)
                     /locus_tag="TU746_000335"
     CDS             complement(12611..13867)
                     /locus_tag="TU746_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL0890720.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(13953..14912)
                     /gene="nrdF"
                     /locus_tag="TU746_000336"
     CDS             complement(13953..14912)
                     /gene="nrdF"
                     /locus_tag="TU746_000336"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL0890721.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(15057..17216)
                     /gene="nrdE"
                     /locus_tag="TU746_000337"
     CDS             complement(15057..17216)
                     /gene="nrdE"
                     /locus_tag="TU746_000337"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL0890722.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(17237..17455)
                     /gene="nrdH"
                     /locus_tag="TU746_000338"
     CDS             complement(17237..17455)
                     /gene="nrdH"
                     /locus_tag="TU746_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL0890723.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            17877..18140
                     /locus_tag="TU746_000339"
     CDS             17877..18140
                     /locus_tag="TU746_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL0890724.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            18145..19878
                     /gene="ptsP"
                     /locus_tag="TU746_000340"
     CDS             18145..19878
                     /gene="ptsP"
                     /locus_tag="TU746_000340"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL0890725.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            20080..21507
                     /locus_tag="TU746_000341"
     CDS             20080..21507
                     /locus_tag="TU746_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL0890726.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            22160..23374
                     /locus_tag="TU746_000342"
     CDS             22160..23374
                     /locus_tag="TU746_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL0890727.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            23470..24039
                     /locus_tag="TU746_000343"
     CDS             23470..24039
                     /locus_tag="TU746_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0890728.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            24040..25992
                     /gene="gyrB"
                     /locus_tag="TU746_000344"
     CDS             24040..25992
                     /gene="gyrB"
                     /locus_tag="TU746_000344"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL0890729.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            26141..27865
                     /gene="ezrA"
                     /locus_tag="TU746_000345"
     CDS             26141..27865
                     /gene="ezrA"
                     /locus_tag="TU746_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL0890730.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            28235..28516
                     /locus_tag="TU746_000346"
     CDS             28235..28516
                     /locus_tag="TU746_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890731.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(28701..29156)
                     /locus_tag="TU746_000347"
     CDS             complement(28701..29156)
                     /locus_tag="TU746_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL0890732.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            29387..30694
                     /gene="eno"
                     /locus_tag="TU746_000348"
     CDS             29387..30694
                     /gene="eno"
                     /locus_tag="TU746_000348"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL0890733.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(30830..31066)
                     /locus_tag="TU746_000349"
                     /pseudo
     CDS             complement(30830..31066)
                     /locus_tag="TU746_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            31275..31496
                     /locus_tag="TU746_000350"
     CDS             31275..31496
                     /locus_tag="TU746_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL0890734.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            31498..31758
                     /locus_tag="TU746_000351"
     CDS             31498..31758
                     /locus_tag="TU746_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0890735.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
     gene            32411..33016
                     /locus_tag="TU746_000352"
     CDS             32411..33016
                     /locus_tag="TU746_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0890736.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            33484..36264
                     /locus_tag="TU746_000353"
     CDS             33484..36264
                     /locus_tag="TU746_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL0890737.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYPDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(36686..36823)
                     /locus_tag="TU746_000354"
     CDS             complement(36686..36823)
                     /locus_tag="TU746_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0890738.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      37067..37185
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            37183..37689
                     /locus_tag="TU746_000355"
     CDS             37183..37689
                     /locus_tag="TU746_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL0890739.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            37786..39744
                     /gene="ligA"
                     /locus_tag="TU746_000356"
     CDS             37786..39744
                     /gene="ligA"
                     /locus_tag="TU746_000356"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL0890740.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            39757..40779
                     /locus_tag="TU746_000357"
     CDS             39757..40779
                     /locus_tag="TU746_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL0890741.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            40788..43088
                     /gene="pulA"
                     /locus_tag="TU746_000358"
     CDS             40788..43088
                     /gene="pulA"
                     /locus_tag="TU746_000358"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL0890742.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            43235..45114
                     /gene="glgB"
                     /locus_tag="TU746_000359"
                     /pseudo
     CDS             43235..45114
                     /gene="glgB"
                     /locus_tag="TU746_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            45181..46320
                     /locus_tag="TU746_000360"
     CDS             45181..46320
                     /locus_tag="TU746_000360"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL0890743.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            46310..47443
                     /gene="glgD"
                     /locus_tag="TU746_000361"
     CDS             46310..47443
                     /gene="glgD"
                     /locus_tag="TU746_000361"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL0890744.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            47440..48870
                     /gene="glgA"
                     /locus_tag="TU746_000362"
     CDS             47440..48870
                     /gene="glgA"
                     /locus_tag="TU746_000362"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL0890745.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            48889..51285
                     /locus_tag="TU746_000363"
     CDS             48889..51285
                     /locus_tag="TU746_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL0890746.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            51627..51824
                     /locus_tag="TU746_000364"
     CDS             51627..51824
                     /locus_tag="TU746_000364"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL0890747.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            51858..52574
                     /gene="atpB"
                     /locus_tag="TU746_000365"
     CDS             51858..52574
                     /gene="atpB"
                     /locus_tag="TU746_000365"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL0890748.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            52592..53086
                     /gene="atpF"
                     /locus_tag="TU746_000366"
     CDS             52592..53086
                     /gene="atpF"
                     /locus_tag="TU746_000366"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL0890749.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            53086..53622
                     /locus_tag="TU746_000367"
     CDS             53086..53622
                     /locus_tag="TU746_000367"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL0890750.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            53638..55143
                     /locus_tag="TU746_000368"
     CDS             53638..55143
                     /locus_tag="TU746_000368"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL0890751.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            55161..56036
                     /locus_tag="TU746_000369"
     CDS             55161..56036
                     /locus_tag="TU746_000369"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL0890752.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            56204..57610
                     /gene="atpD"
                     /locus_tag="TU746_000370"
     CDS             56204..57610
                     /gene="atpD"
                     /locus_tag="TU746_000370"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL0890753.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            57623..58039
                     /locus_tag="TU746_000371"
     CDS             57623..58039
                     /locus_tag="TU746_000371"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL0890754.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT        16441 a        11078 c        13569 g        17058 t
ORIGIN      
        1 acgtctcaag gagtgttacc ctcaattatc ctttgcagag ccaatgatca gttctacgat
       61 ggccttagag tctatcaagt tgtcggcaag ggttagtctt tttaagacaa tcaaaaatgt
      121 aagcgctatc aagaaaagtt tttatccttg taatatggag gagctagatc aaccaacggg
      181 ctacctactg tatagaacgc acctcgctag acatagcaag gaggagcggc tcagggtcat
      241 tgatgctaga gaccgcattc agctcttttt agatgaaaag cacgtgaaaa cccagtatca
      301 ggaggaaatc ggtcaggata tactgataca tcaagagggt gagaccacac agcttgatat
      361 tttagtcgaa aatatgggac gtgtcagcta tgggtacaag ctgacagcac caagccaaca
      421 aaaaggatta ggcagaggct taatggctga cttgcatttt gtaggtgatt gggagcattt
      481 tccactagat tttcaagagc tggattggat tgatttttct gcaggttgga ccgatgaggt
      541 gccaggattt tacgcctatg attttgattg tcagcagccg gcagatacct accttgattt
      601 gagtcaattc ggaaaaggaa ttgcccttgt aaatggtgtt aacctaggac gtttttggaa
      661 ggtcggtcca acattatcgc tttatattcc taagggacta ttaaaacaag gtcaaaatag
      721 actgctgata tttgaaacag aagggcagtt tagtgagtca attcgtttaa ctaaggaacc
      781 aatttataaa tagataaaag gagaaaactt atgacaattg ttgcagcacg tattgacggc
      841 cggttaattc atggtcaggt agctaatcta tggacgacaa agctaaacat tagccgtatc
      901 atggtggtcg ataatgaggt gattagcaat gaccttgaaa aaacagcact gaagctagcc
      961 acacctagcg gtgttaaatt atctatctta tctgttgaaa aagcagccaa caatattttg
     1021 gaagggcgct atgattctca acgcttgttg atagtagcca gaaagccgga tagctttttg
     1081 gagctgattc aaaaaggggt tgctatttca gagttaaatg tcggcaatat gtcacagaca
     1141 ccggagactc gtccagtaac gcgttctatt aacgttgtag acgaggatat agaggcattc
     1201 aaggctattt cagccaaagg gtgtcatctc attgcccaaa tggtgcctaa tgatgcccca
     1261 gcagacttta tgccgctgtt ggataaggtt gattaagatg tgtcaaatca aaaacgaatc
     1321 tgtttcagga ggtaaaagct tatgattcaa tggtggcaaa tcctattatt aacactctac
     1381 tcagcttatc aaatattaga tgagctaaca attgtctctt ctgcaggctc acctgtattt
     1441 gcaggattta tttcaggtat catcatggga gatgtgcaaa ccggtctttg gattggtggt
     1501 agccttcaat tgatggtgct tggtgttggg acctttggag gagcttcgcg tatcgatgca
     1561 acctctggtg cggttattgc gacagccttc tcggttgctc aaggcataga gccagaatta
     1621 gcgatttcaa ccattgcagt tccggtagcg gccttgctgg tttatactga tattctagga
     1681 cgcttttcaa cgaccttctt tgctcaccgt attgaccgcc atgttgaaaa ctttaactac
     1741 cgaggcatcg agcgtgatta ccttatggga gctgtacctt gggccctatc acgtgctctg
     1801 ccggtatttt tagcggtctc tttaggtggt ggtgcggttg atacagttgt taagttcatt
     1861 gaccattatg aatggctagc aaatggtcta actcttgcag gaaaaatgct tccaggcttg
     1921 ggctttgcga tcttgcttca ctacctacca gttaaacgta atctccatta tctggcttta
     1981 ggttttggct tgacagcaat gctaacaacc atttacacca accttcaggt agctggaggc
     2041 gcccttgcag gagtagccaa ggatttcaat gccgcaccat tcaaggggct gccaatgatt
     2101 ggtattgcta ttattgggct ttccttggca accctccatt ataaaaatgg tcaacaagca
     2161 cctgtagctg aacaaaaacc tggggtatca gaaagtgggg aaattgaaga tgacgaaatc
     2221 taattataaa ttaaccaaac aggattttaa tcaaatcaat aagcgcagcc tgttcacatt
     2281 ccaatggggc tggaactacg agcgtatgca gggctctagc tatctttaca tgattttacc
     2341 acagcttcgt aagatttatg gcgatggaac tccagagcta aaagaaatga tgaagacgca
     2401 cacgcagttt tttaacacat caaatttctt tcatacgatt atcacaggaa ttgacttggc
     2461 gttggaggaa aatgaaggac ttgcctcaaa agatgctgtt aatgggatta aaacaggctt
     2521 aatggggcca tttgctccaa ttggtgattc ggtctttggc tccttagtac cagctattat
     2581 gggctctata gccgcaggtc ttgctaaaga aggggtttgg tcagggatta ctggtgtatt
     2641 gatgtgggta tgtactcaga tgatcatcaa tgtgtttcgt tggaagcagc ttgaaattgc
     2701 ttataaagaa ggtacaaagc tcgtcaccac catgcgtgat aagctaactg ctgtagtaga
     2761 tgcagcctca gtcatgggag tattcatggt aggggcctta attgcaacaa tgattaattt
     2821 tcagtttacc gcagcaccca aaattggaga gaaagttatc aatattcaag atttaattga
     2881 taccattttt ccacgtctag ttccagcctt atttaccgga ggtatcttct ggctgctagg
     2941 gcgtaagggc atgtcaccaa ctaaggcaat tgttgtgatt attttatttg ccttagtgat
     3001 gtcttatttc aatattttag gagtatagct gatggcgcaa accttaattc tcattagtca
     3061 tggagctttt tgtcgagagc taaaacagag tacagaaatg attatggggc cacaggacaa
     3121 tattttaaca gcagagctgc aaccaaacga aggtgccgat gactttaaag aaaagctttt
     3181 aaggctaatt gcaggtttag atgacgtcct tgtgtttgca gatttgatgg gtggaacacc
     3241 ctgtaacgtt gccagtcgtt tgttaatgga aggacatcag tttgagctgt acgcaggcat
     3301 gaatatgcca atggtcattg gtttcattaa tgcctgtttg atcggtgaag cgtttgattt
     3361 caaagccttt gcctgtgaca atattcacca tgtcaatacc attatttcag ctctagcaga
     3421 tgatgatgac gactaaccaa gctcgcttat ttgtcacgca ccttacggag cgaaacggac
     3481 caagagccgc ataatcaaaa aagacactgc caaatcttgg cagtgtcttt gctgtaagct
     3541 tattttgctg cgtttgcgtc tttgagaccg tatttcttgt tgaaacgatc cacacgtcca
     3601 tcggcttgtg taaacttttg acgacctgtg tagaatgggt gtgagtctga tgaaatttct
     3661 acacgaacaa gagggtaagt ttccccttca aactcaatgg tttctttaga ggtcttagtt
     3721 gaaccgctaa ggaatttgta gcctgtagtt gtatcaagga aaacaactgg acgataatct
     3781 ggatgaatgt cttttctcat cttaaaaaag ttcctttctg ccatgatact gtccgtatca
     3841 tagttattaa ctactctagt ttaacaaaag ttagtaagct tgacaagctt tttctatcac
     3901 tattcatcaa taagatgata agtcttatgt taagagatca atcagctctt ggtagatttg
     3961 ctcattttcc tctaagcctg atgacgtggc accgctagca agagggtgcc cgcctccttg
     4021 atgacgctta gcaataccat tgatgacctt ttctttactg cgcatgcgta ctcggtactg
     4081 gccatctggc agctcaacaa agataaccca agcctgcacc acgtctattt ttccaggagc
     4141 agagacaatc gctgagcttt ctgccaagct aataccaaag gaatttagga cctcctggct
     4201 aagcagtagg cgggctgcac cactgtcatc tatatcaagc tgctcaaaaa catagccttg
     4261 tagcttggca attttaagtg gaaaggaatc catctgcctc gaaatagcag caaagtcaaa
     4321 ggcataattt cttaattggc ttgcaatggc cagtgtttta ctgcttgttg aggcatagag
     4381 aaagcgtcct gtatctccca caatgccagt atataatagt ctagctgcct catcagttaa
     4441 agccaagcct tggctaaagg caaattcagc aataatctca ctagcacttg aggtcttggt
     4501 gtcaacgtag gagagatcac catagacatc atcgttaggg tgatgatcaa ttttaatgag
     4561 gcaagcgccc attgtgtagc gctcatcatc aatgcggggg cgattggcag tgtctgtaac
     4621 aatcactaaa gcttccttat aatcatcgtc ggacacctga tccatgagac taatccaagc
     4681 cagactaggc tcatcaaagc ctgttatcag gacctttttg tcagggaaat tatgcctgat
     4741 aatctcttta agtcctgctt ggctccctag agcatctgga tcggggtttt ggtgccgatg
     4801 aatgatgatg gtttgatagt gcttaatgtg ttctaaaata gtttgaaacg ttgtcatagg
     4861 tatcctttag tttttgatca tatcaatgtg aggaatattg tcttccagat aaatctcaga
     4921 gactgcttta aacccaaatg agctgtaaaa aggctcaaga taagcctgcg cttgagcgta
     4981 gacgggaagc tttggaaagt gctgttgaca ataggctaag gcttgatgaa ctaagtcacg
     5041 tcctagtcct gttcgccttg cattttgtgc taccagtact cgtcccagct ttatgctatt
     5101 gtcagttggg attaagcgac agtaggccct aagctctgaa tcaacctgct tgaaaagatg
     5161 gatagctttt tgatccaaat cgtcaatatc aggataggga cattgctgct caaccacaaa
     5221 aacagccaca cgctctttat agatggcaaa caattcatct tttgttaact gatcaaatgc
     5281 tttaacaacc cacattagct agcctccaaa atcactggta caatttcctt tatgataaca
     5341 taatagcata tatcagccat aatggaacga aaaaaacctg actcttaatg gacgatgtcg
     5401 tgatgataat tacatcttgt ctcaaaagct ggtaatcatc acaggcacag aaaaatgtgc
     5461 cccttctgtt gctttttgag aaaaagttca cttgcttttt ggtagttttt tggtatcata
     5521 ctaaaaaata gacttaatta aggagataca gcttggaaac aaaagattta aagaagcttg
     5581 ctaaagctga gctgcactgc catttagacg gttctttgtc attagacact attcgtcagt
     5641 tggcggcttt ggcgcaggta gatgttcctc aagatgattc tgagttaaag cagctggtaa
     5701 ccgcaccgga aacctgtgaa tccttgatgg attatttaaa aacctttgat gttatcagac
     5761 cattattaca aacgcctcag gctttaacat tggctgctta tgatgttgtg aagcaggctg
     5821 cccttgaaaa tgtcatctac attgaaattc gatttgctcc tgagttgtca atggatcagg
     5881 gcttgaccgc cactcaggtg gtagaggcag ttttaaaagg actcgagcaa ggacaaaaag
     5941 agtttggcat tgtcgctaag gctattgtgt gtggcatgcg tcagtcctca ctagacatta
     6001 gcagagagat ttttgcaaat gtcttagagt gggccaataa aggcttggta ggctttgatt
     6061 ttgcaggcaa cgagctggac tttcctccag ctgtcttagc agatttgatc aaagagacgc
     6121 aggcctatgg gttaccattt acgcttcatg ctggtgagtg tggctgtcca aactatattg
     6181 ttgatgctat tgatttaggt atcaaacgct tagggcatgt gacggccatt cataaccaaa
     6241 aggatttatt ggccaagttt atcgccaatg atgtgacagc agagctgtgc ttcactagta
     6301 atctacaaac caaggctgct aggactgttg aggactttcc ttatatgcag ctaaggcagg
     6361 ctggcgctaa attatccatt aacacagaca atcgaacagt atccgatacc aatctgacaa
     6421 aggaatatga actgtttgtc aagcactttg agacaagcgt cacagacttt ttagagcata
     6481 atcgtgatgc tattaaggct agttttgcca gtccggctga aaaagaagct ttattggatc
     6541 gtttggaaaa ggcttatcag tcttacatca agaaataatg cttttcttgg caaagtatga
     6601 taaaatatac tgacatttag ttattttggg aggaaattat ggcattagcc aaaatcgttt
     6661 atgccagcat gacaggaaat actgaagaaa ttgctgatat tgttgctaat aaattgcaag
     6721 aattgggaca tgatgttgag gttgacgagt gtacaacagt tgatgcttca gagcttgagg
     6781 ctgctgatat ggcaatcgtt gcgacctata cctatggtga tggggactta ccagatgaga
     6841 ttgtcgactt ttatgaggac ttgcaggatt tggatttgtc aggcaagatc tacggtgtcg
     6901 tgggctctgg tgataccttt tatgattatt tctgcaaatc agttgatgat tttgacgaac
     6961 agctcgctgc cactggtgcc actaagggag ctgactcggt taaggttgat ttagctgctg
     7021 aggaagagga tattgctcgc ctagaatcct ttgctgagca aatgtcacag gcattagagg
     7081 cataagtaag acttttgata cagattggta aaacggtcag tggaggcttg cgttttttac
     7141 caccaaatgc atgaaaaact gatattttct gatcgttttt tcatgactat gtgctctttt
     7201 tcaagaaaag tcatgccatt attagcctga atgcaaacaa ttgatagtgt caaaatgttg
     7261 atcatatagt aaaaaaatgc atgtgactag aaagcagtta catgcatttt cgtcatgcgt
     7321 ttgtcgtgag gcattttggg ggttacttgc ttactgagct gaaattcact ataataaaaa
     7381 gataaataaa gaaaagaaga agttaggtga atgatgggat tagagaccat acgacaagac
     7441 attaatgctg ttgatcgtca gttgattgct ttgctggaaa agagaatggt cttggctgac
     7501 caagtagcgg cctataagca ggtacatgat gtgccagtgc ttgatcaaga gcgagaggct
     7561 gaggtcctaa ggagcgtgtc acagcagatt cggcataagg cctttgagcc tgccattctt
     7621 gagctattta agacaattat ggcagtatca aggcgttatc aggctgagca aatagcggtt
     7681 ggttcaaatg atgatgaagc ctattaaaaa caatcaagac atcagtatag gtgataatgt
     7741 ctatttggct tttgcagccc tgctcgttgg ggtggtggta ggtgtgatag atactgtttt
     7801 tggacaaggc ttgttgctct tgtctgctgt tcgtgatgct catctcattt acctgttacc
     7861 ctgcttagct cttgctggac ttgtgattgt gttcttatat gagcaatatg gccaaatcgc
     7921 taagcagggg atgggcttag tttttgatgt ggggcatggt gaaaaaacaa gactaccact
     7981 ggtgttgatt ccgttgatta tcctctcaac ctggctgacg catttatgtg gaggcagtgc
     8041 tggtcgtgaa ggcgtagcgg ttcaaattgg agcgacagtg tcacattttt ttggacgtct
     8101 tagacatctt aaggacaagt cacagctgtt tttagtcatg ggaatggccg caggctttgc
     8161 gggcttattt caaacgccaa tgacagcggt tgtttttgcc ttagaggtcc tgttgctagg
     8221 aaatataagc tatttagcct tgctaccttc tcttatagca gcctttaccg cctcttggac
     8281 ctctcattgc ctaggcttag aaaaattttc agtcccgata gccaaggcct tgaaaatcac
     8341 cccgataacc tttgggaaat tagtgctact aggccttatt tttggcttgg ctggtaatct
     8401 ttttgcctcc ttgttagcaa gggctaagcc atacattgca gcaaggctgc caaatcctta
     8461 ttatcgtgtg ttgcttgttg gtggttttct atcgcttagc ctgctgctgt gccattacgg
     8521 gcgctatagt ggcctaggga ctaacttaat tacagcggcc tttagtcatc agcctattgc
     8581 taattatgat tggctattaa agctcttgtt taccattatc actctctcgg ctggctttca
     8641 gggcggtgag gtcactccac tttttgctat tggtgcggct ttaggaattg tcctagcacc
     8701 atggcttggc ttgccggctc agttggctgc agcccttggc tatgctgcgg tatttggcag
     8761 tgccaccaat acctttttag ccccgatatt tgttggatta gaggtttttg gtgcaacaaa
     8821 cgcaactgct tactttatcg tgatagcctt tgcttatatg gtgagccgaa ggcattcaat
     8881 ctacactaag caaagggtga ccactagcat cgcttcctag tgtcttggtc agttttttgg
     8941 agaaaatagc tttacaagtg gggcttattt tgttacaata ggctccgtgt gtaatggacg
     9001 cacaaaaatt acggctaatc cgctaagact cgcgcttaag attagtaaga taaggagaat
     9061 aaacaatgaa tccattaatt caaagcttga cagagggtca acttcgtact gatattccta
     9121 gcttccgtcc tggtgacact gttcgtgtgc acgcaaaggt tgtcgaagga tctcgtgaac
     9181 gtatccagat ctttgaggga gtagtcattt cacgtaaaag tcaaggtatc tcagagatgt
     9241 atactgttcg taagatttct agtggtatcg gtgtagagcg taccttccca attcacacac
     9301 cacgtgttga aaagattgag gttgtgcgtc atggtaaggt tcgtcgtgct aagctttact
     9361 acctacgtgc cttgcaaggt aaggcagcgc gtatcaagga aattcgtcgc taaaaagagc
     9421 atacgagagg tttttcactg tcttatgaaa ggactgctgg agcagcaggg tctttgggac
     9481 aagctttttt tcgcaggtat gtgaacctac gctcaattca agacatatca aaggctcatt
     9541 ctatgataga gtgggctttt tgattgtgat catgctttag tgcctaaata aatgacagca
     9601 gcctgactaa tgaaaggctt acttgacttt ggaaatgctc aaggcttgcg ctaccagata
     9661 gaagctgaca tcatgccata gcagtcaagg ggaagaagga ctagattttt tggcgaggtg
     9721 ttgatctgtg accctgatgt tgttgggaat atgagagtaa tttaaaattt cgtcttgcat
     9781 tctacctttt tctaggttac aatagacaag taacctgatt agtgaagcta aaagacgtag
     9841 cgatgggttc taaaaaagaa tgattctggc gtttttggct aacctaagct gatagctttg
     9901 ctaggcagtg tcttagtcat ctggtcagtc ctgctagttt aacggataaa acaagcgcct
     9961 cctaagcgct agctgtgggt tcgattcccg cgcgggacat taaaaacaaa gtaaaaagag
    10021 tctgagaagg tttgagctgc ccctaattgt tagatttttt tctaactctt gaagtgtggg
    10081 tcaaagacta tttgtctcag gactcttttt aattggtttt tactaagctg cttcatctag
    10141 ttcttcagtt gctaagttgt ttccttcttc tgtatgttgg ttttcatcaa gtagcattcc
    10201 tgtgcggtaa tctaatgctg ccaaaggtga tacattatcc agaacaactg aggttatacc
    10261 ataatgatca acggattctt tgttgcctcc caatttgatt tggaggagct ctccgttttg
    10321 atcaattcca acgtactgta acactacttg acgaggaact aattcatcat tctgataaat
    10381 aggagttacc ttataatcta gccaaaagtt agggtgtatg gctaaccaat tgtctagtct
    10441 attttcataa taaagcattc ctaaaggatt tttatcacta aaacctgtat taaggtattt
    10501 tgtcatagta actaaatttt tgggttcatc atttaggccg ctaaactgat aaccgactag
    10561 atgtccgcga tccattaacc aagtcttttt ccctctagaa ttaatgactt gatagttatg
    10621 ccagccggga ggattaaatc taagcgcttt tcttttgaga gttggttcat cttgatcttt
    10681 gagttgtatg tgtgcatagg tggctctttg taaatgatca agatctccca gagctatttg
    10741 gtattttcca gtaaacggta aaattcctgg tatttcggta gcttttgttc ccaatgatat
    10801 ttccgttgta tctgggaagg ttctaagttt tcttgcagat tgaacagagt tagctgtgaa
    10861 aatagtcaga atagttaaca aaacaattgt tagacttttc cagttacggc gacgtgattt
    10921 agacatatca atgccctcct ttttttgttt acgagttaag tatatcactt ttaattaaaa
    10981 aaacttaaaa ttaataaaat tattttaatt ataatattca tctaaattat ctttattttt
    11041 aattcaaaaa tataagcaat tgattcacat aaacaaattg agacgaacag tagattgtag
    11101 ctatatcaca ggtgagatag taatgatcgt gcgaaacaat aaactgattt ttccatgcgg
    11161 gatatttgtt atcagtgagt tgaatggaac tagcagctat tgttttattg ttagtcatct
    11221 agtgttttta aggtgcttat tttctgttac aacagtgatg acaacaggtt aagctaagtt
    11281 cgatggagct tggtttttta ttgttacaag aaagctcata gatggtgatt gcattctttt
    11341 atcatatgac aatgtttcta tttttgacaa atattattgt caaaaagtaa atgatctgtt
    11401 acactggagt tggactcatg aaagaaaaaa gtaatcagta ggataacaat aacaaagcta
    11461 ttttaagctt ataccattgt gtcaatggat tgttgccgga aatgactggt gctttctgtt
    11521 caatcaggag acagcattta ttaggagtga agcatggctt ataggttgag aaatcggctc
    11581 aaggagctac gagctagaga tggcattaat cagacgcaga tggcagcatt agcaggtgtt
    11641 tccaggcaga ccattagcct cattgagcga aatgaataca caccatctat tattattgca
    11701 atgaaaattg ctaaagtatt taatgaacca attgaacaag tatttagctt agtggagggc
    11761 gagagatgaa agcttttatg acggaaaagg acagtacgtt ggtgagaata cttaagtcat
    11821 tactgcttgg atcagggatt ggcttagtgt taggtggcct tgttggtttt ggtttagcta
    11881 ggtttaacat attagaaaat ggctttccga tatcagaaga agacaccata actggaataa
    11941 agtggggaat gagacccctt gttatcgtgc ttatgctgct gagcatttat gatatttatc
    12001 aagttgtcaa agaatatgct agatatgtca agctaagcga tgatgaaaca gaggagctgt
    12061 accgttacat taatcttaag catgcctatg ctttaggatt tagcgctatg gctatggtct
    12121 tgaatatagt cgttttttct ttgggatata gggtgcctat tgctaataat gctagctatc
    12181 ttggtttgac ttttcctatt tacgaggctc tgatgcttgt ggttattagt gttctccatg
    12241 cttatatttt gaaggtttat actcggattc gcggggtcaa gatgacgctt gctcctacct
    12301 taaaggaatt aaagcagaat atcttacaac aggacgaggc agaattgcag gctaattatc
    12361 aaatgtcttt tgaggttgtc atgggcctta gtggctttat attaccaggc atttacgtaa
    12421 tattattgct tttatctatg atttttcaaa gggttgagct gaccggacta atcattactg
    12481 ctagtattca cctctatatt ctggtgaaat cctttaaatc agcacatgat ttttataggt
    12541 aaggcgtaag gttttaccta ctcaagaatt gttatacagc aaaaaagctt tgataagcca
    12601 ttactggcga tcaaagcttt ttgtgtttgt tgaaaaagag gcttttttga aagagctgtt
    12661 ggctgagata gcttgtcaaa cctacaattg caagcggcac aaggctaatg agaggttgtc
    12721 cggtaatttc aatgagaaaa agaggagcag taagaggtat ctgattaatg attcccaaaa
    12781 agagggtcgc tccaatgaca atggccaagg gaagtggtac agagagataa cctagctgat
    12841 tgctaaggct tgccagtagc aagccactag ctcctccaag catcatagaa ggagcaattt
    12901 tgcctccttt agctccagag gcaaatactg catagacagc agctgcttta cttagtaaga
    12961 gcgaggcggt ataagatagg ctgacatcat ggtgtagcag caggaggaga ccggccttgc
    13021 cattgcctaa aatctctggg aaataaaggc ttaaacaagc actaaagcca aaagccccta
    13081 agacacgagg gataaaccat cggctcttag gctttgcctt tggtgcgttt tggagcagct
    13141 gctggtagca aaaggccaga aatgctaaga tgggactggc aatgatagcc caaaggactg
    13201 ttgtcagttg ccaggcttgt gggagaatga gatactgtat gtcctgatgt ccgcttagaa
    13261 caagcacact ttgaacagca gtaaaggcag ttatagctgc cgcgtaaatg tgtttaactg
    13321 agcatttttt gacaatagcc tccatgataa agacaatcgt agctaatggt gcctggtaaa
    13381 cagctccaag ggcagctcct gaagcacagg ctaaaagcaa tccttgctct gctgctgatg
    13441 cgtttatagc tttattgcaa gcggcagtca gtgccacagc aacctcacgt gaagcacctt
    13501 cacgaccgac aggtgctccc atggagacgg ttattaattg cagccagcca tgacaaaatt
    13561 gtgtccaagg gctgaaatcc ttttgctgac tgagtgtttg ttggataggc tgaataggct
    13621 tggctttttt agcaagtagc tgccagccga gaccagcaat agctccagcc aacaatagag
    13681 ataaaaaacg cctttctgga gctaccgttg caatcatggt gctaaaagac ccagattggt
    13741 atccaaagct aatagcctgt atgaaatgaa tggcttgagt gagcacgtaa gccaccacac
    13801 cagcaatcac accagctacc accagttggc ccgtccatgt taagaaagta atcaatcgag
    13861 taatcatatc ttttattata gcagataaaa agagcctgag actactcagg ctccaaaata
    13921 tagataaatc caatcttcat gagaagctgg acttatagcc cataattgta atcgtcatca
    13981 gtcatagctt caacagtacc aagaaggtag ccattaccaa cttgagagaa gaaatcgtgg
    14041 tttgacgtgc cggttgaaat accattcata acgattgggt tgacatcatt ggcagtgtct
    14101 ggaaaaagag ggtcctgacc aaggttcatc aaagccttgt tagcgttgta gcgtaggaag
    14161 gtcatcactt cctcggtcca gccaacctca tcatagaggg tcttggtgta ttgctcttca
    14221 ttttcatata gctgatacag caggtcatac atccagtcac gaaggctttc ttgctcactc
    14281 tctgatagct cattaaagcc cagctgaaac ttgtagccga tataagtgcc atgaacggac
    14341 tcatcacgaa tgatgagctt aataatttca gcgacattag ccagcttatt gttgcccaga
    14401 taatagagtg gtgtaaaaaa gccagaataa aatagaaagg tttcgagata agtcgaggct
    14461 accttttttt gaagggcact gccattttca taaatgtcgt tgattatctt agccttattt
    14521 tgaagaaata cgttgttgtt ggtccactca aaaatgtctt caatttcttt tttggtgttt
    14581 agggtcgaaa agattgatga gtaggattta gcatggacag actccataaa ttggatattg
    14641 ttaagaactg cctcttcatg cggggtgcgc acgtccttgc gaatggcttc gactcctgac
    14701 tcagactgca tcgtatcaag aagggttagc ccgccaaaga ccttacctac taaatccttt
    14761 tcaacagcag ataatctgcg ccagtcatca aggtcatttg atagtggaat acgtgtatca
    14821 agccagaatt gctccgtcag cttttcccag gttgacttgt caatgacatc ttcgatttca
    14881 ttccagttga ttgcttcata gtatgtggtc atgagtttct ccggtagatt gtaatatagg
    14941 gttaggtatg ctaggaggag agccttgagt gctggtctat cattaggaca ggtgcactga
    15001 cacatcagct aggctctgac attaaggact ggtccacctc actgccattc acttggttag
    15061 atgacacagc tttcacactg attggctccg acctcctcgc catcatcggt aaaggtgcgg
    15121 atataataga ttgattttat ccctttatta aaggcgtaat gtctcaaaat agataggtca
    15181 cgagtggttt gcttgctttc tgttttccat tcgtagagct cctttggcaa ttcgctgcgc
    15241 aaaaagagtg ttaacgacag tccctgatca acatgctttg tagcagctgc atagacatca
    15301 atcacctttc tcatgtccat atcataggca gatgtgtagt aaggaatggt gtctgtagat
    15361 aggccgttgg ctgggtaata aatcttgccg attttctttt cctgacgttc ttcgatccgc
    15421 tgagtaatcg ggtgaataga agcagagcag tcgttgatat aggaaattga tccattagga
    15481 gcaactgcca gacggttttg gtgataaagg ccatctgtca taatcgcttg acgcagcgcc
    15541 ttccagtctg ctgcttgcgg aataaagtga tccttgaaaa ggcttttaac cagctctgat
    15601 tttggcacac attctcctgt gatgtactgg tcaaaataag caccgctagc atatgttgat
    15661 ttttcaaagc caacaaaggt tgtctgacgc tcgcgagcga tctgattgga ttcgacaagc
    15721 gtccagtaat tcatcagcat aaagtaaata tcagtaaatt cgatagattc tgggctgcca
    15781 tattcgatat ggtgctgagc caaataggaa tgaagcccca tagccccaag gccaaaggta
    15841 tgtgcttgac tgttaccatt tttaacagtt gggactgctt cgatattaga ggagtcagtg
    15901 acaaaggtca gggcacgtgt catggctctg atggaacgac caaagtcagg tgacgtcatc
    15961 atgtttaaga tattagttga tcccagattg caggaaatat cagttcccat tttgacaaac
    16021 tcctgcgcat cattaatgag actaggcgtt tgaacctgta gaatttctga gcataggttg
    16081 ctcatgatga ttttaccgtc aatagggttt gacctgttgg cagtgtcgat gttgataaca
    16141 tagggatagc cagattcctg ctggagcttg gaaatctctg tctccaaatc acgtgctttg
    16201 atttttgttt tggtgatatt aggattggca accaattcgt catacatgct agtaatatca
    16261 atgtagttaa atggcaggcc gtattctctt tcaacactat aagggctaaa gagatacatg
    16321 tcagcattgt gacgagcaag ctcataaaac ttatctggta cagtaatacc aagtgacaat
    16381 gtcttgaccc gcaccttttc atctgcattt tcttttttgg tagacaaaaa agcgataata
    16441 tcagggtgaa agacgcttaa atacaccaca ccagcccctt gacgctgccc tagctggttg
    16501 gaataagaaa agctgtcctc aaatagcttc attacaggca caacaccaga agcagctccg
    16561 gcatagccct tgattggagc gccagcctca cgaaggttgg ataggctaat gccaacacca
    16621 cccccaatac gggataattg caaggcagaa ttaatagagc ggccaatggc attcatatca
    16681 tctgtcacct gaaggagaaa gcaagaaacc agctcaccac gacggctccg tccagcattt
    16741 aaaaaagaag gagtagcagg ttggtaacgc tgattaatca tctcaatggc taagtcctta
    16801 gctaatgttt catcaccatc agcaaaataa agggcattga acatgacccg atcctctatg
    16861 ctctctaagt agaaattgcc atcattggtt tttagggcat actgctgata aaatttatag
    16921 gccgccataa atgatttaaa gcgaaagccc tctgcttgaa tgctcttggc tagatggctg
    16981 ataaattcag gagaatagtt ttggataaag gctgattcaa tatagtcatt gtctacaaga
    17041 taggcaatct tttcgttgat agaagaaaat gacatggtgt taggaataac attttcggta
    17101 aaaaaagcct ccaaagcttc cttgtcttta tgaagtggaa tgctgccatc aacaggacgg
    17161 ttaatttcat tgttgaggcg aaagtaagaa atatcgccaa gatctttgag actcatatca
    17221 attgttcctt gtctagttaa ataatatctt ttaattttgc tggctgaaac cctgagaata
    17281 ctatctgctc tgtctcaata acaggagcag cagtaaagcc aaggctctta acatagtcca
    17341 ctttttctgg atgctcatca atattaatct cttggaaagc agctccatgc tgttctaaaa
    17401 atttcttagt cattttgcac tgcatgcaat tgtgctttga gtatactgta atcattgctc
    17461 gtccttccaa ctattagtct ttcactcaat tttaggaaaa atcaaatgac tctaatagga
    17521 tataaaaaat gttcctaaaa agcaaacgat ttatttcaga atagcacaag atattgtggt
    17581 tgtgtgtgag aatatttcta aatattgtgt tatcctctct tatcactgat aattgctaca
    17641 agaggcttgt agttcttaaa tgcatactaa tcaggttgga aggcttattt gacattatga
    17701 aaatcatcat gtaagaaata ttgacaacaa atgaaaatac aagaaaactg tttcatgatt
    17761 ttttcttgtt agaacattta accttgaaaa taaaaaagca ttgtgctata atcacttatt
    17821 gtaagggtta tcatgtgata gctcgaaaat acacaattca aaaggagaac catattatgg
    17881 cttcaaaaga ctttcacatt gttgcagaaa caggtattca tgcacgccca gctaccttac
    17941 ttattcaaac agcaagcaaa tttgcttcag atattacact tgactacaaa ggtaaagcag
    18001 taaatcttaa atcaatcatg ggtgttatga gccttggtgt tggtcaaggt gctgacgtaa
    18061 caatcacagc agaaggcgct gatgcagatg acgctattgc ggcaatcgaa gaaactatga
    18121 ctaaagaagg attggcataa gactatgaca gaaatgctta aaggaatcgc agcctctgac
    18181 ggtgttgctg ttgccaaagc atatctgcta gttcagccgg atttgtcatt tgagactatc
    18241 acagtcgagg atacaaatgc agaagaagct cgccttgatg ttgcactaca agcttcacaa
    18301 gacgagcttt ctgttatccg agaaaaagca gtagaaagcc taggcgaaga agcggcagca
    18361 gtttttgatg cccatttaat ggttcttgct gatccagaga tgatcagcca aattaaagag
    18421 actattcgtg cgaagcaaac gaatgctgaa acaggtctaa aagaagtgac tgacatgttc
    18481 atcacaatct ttgaaggcat ggaagacaat ccttatatgc aagagcgtgc ggctgatatt
    18541 cgagatgtcg ctaagcgcgt cttggctcat ttattaggtg ttaagcttcc aaatccagct
    18601 acaattgatg aagaagcaat tgttattgca catgatttga ctccttcaga tactgcacag
    18661 cttaacaaac aatttgtaaa agcatttgta acgaacattg gcggacgtac gagtcattcg
    18721 gctatcatgg cccgtacact tgagattgcg gctgtgcttg gtacaaatga tattactaag
    18781 cgtgtcaaag atggtgacct tattgctgtt aatggtatca ctggtgaggt tattattgac
    18841 ccaagtgagg agcagattct tgctttcaag gaagctggag aggcttatgc gaagcaaaag
    18901 gctgagtggg ctctgcttaa ggacgcacaa actgtcacag cagatggcaa gtactttgaa
    18961 ttagcagcaa acatcggtac acctaaggac gttgaaggtg tcaacgataa tggtgctgag
    19021 gcggtaggtc tttaccgtac tgagtttctt tatatggatt ctcaggattt cccaaccgaa
    19081 gatgagcaat atgaagccta caaggctgtt cttgaaggaa tgaacggcaa gcctgttgtt
    19141 gttcgtacaa tggatatcgg tggggacaag gagcttcctt actttgattt accaaaggaa
    19201 atgaacccat tccttggttt tcgtgcctta cgcatttcaa tctctgaaac aggtaatgct
    19261 atgttccgca cacaaattcg tgctttgctg cgtgcttctg tgcatggtca attgcgtatc
    19321 atgttcccga tggttgccct tctaaaggaa tttcgtgctg ctaaagtcgt atttgaagaa
    19381 gaaaaggcta gcttgctgtc tgagggtgtt gcggttgcag acgatattca ggttggtatc
    19441 atgattgaga tcccagcagc agcaatgctt gctgaccaat ttgccaagga ggttgacttc
    19501 ttctcaattg gtacaaatga ccttatccag tacacaatgg cagcagaccg catgaacgag
    19561 caagtgtcat acctttacca gccatataac ccatcaatcc ttcgtttgat taacaatgtt
    19621 atcaaagcag ctcatgctga aggtaagtgg gctggtatgt gtggtgaaat ggcaggtgac
    19681 caacaggctg tgccgcttct tgttggtatg gggcttgatg aattttcaat gtcagcaaca
    19741 tctgtgcttc gcacacgtag cctgatgaaa aagcttgatt cagcgaaaat ggcagagtat
    19801 gctcatcgtg cactcacaga atgctcaact gctgaagagg ttcttgagct tgccaaagag
    19861 tatattacag aagcttaaat agaaataacg aggagctggt tttgtccggc tcttttttac
    19921 tagaaaaatg actaatcaga tccatatgaa agcttgcttt ataaagtagt ttgatgtttc
    19981 aagttttatc agaattttca gactcttcct gtagcgaatt gttgaaatat gctaaaaaag
    20041 tgatagaata atagtaccat tataaaagga gaaaaaagtt tggctaaaca atataaaaat
    20101 ttagtgaatg gtgagtggaa gctctctgaa aatgagatca agatctatgc accagcaacc
    20161 ggcgaggagt taggtagtgt accagctatg tctcgtgaag aggttgatca ggtttatgcg
    20221 tcagctcgcg ctgctcttgc agattggaga gcgctttctt atgttgagcg tactgcttat
    20281 ttgcacaagg ctgctgatat tttggtgcgt gatgctgaga agattggtgc tgttctctca
    20341 aaagaggttg caaagggtta taaggctgct gttagtgagg ttattcgtac agcagaaatt
    20401 attaactatg cagcagaaga aggccttcgt atggaaggcg aggtccttga gggtggcagc
    20461 tttgaggctg ctagtaagaa aaagattgcg atcgtacgtc gtgagccagt gggacttgtg
    20521 cttgcgattt cacccttcaa ttatccgatt aacctagcag gctcaaagat tgctccagcc
    20581 cttattgcag gaaatgtcgt ggttcttaag ccgccgacac aaggctctat ttctggcttg
    20641 ctcttagcag aggtatttgc agaagcaggt cttcctgctg gagtctttaa taccatcact
    20701 ggacgcggct cagttattgg tgattacatc gttgagcatg aggctgtaaa ctttatcaac
    20761 tttactggct caacgccaat tggagagcga attggtaaat tagccggcat gcgtccgatt
    20821 atgcttgagc ttggtggtaa ggattcagcg attgtcttag aagatgctga tattgcctta
    20881 gctgctaaaa acattgttgc aggtgccttt ggctactcag gtcaacgctg tacagcagtt
    20941 aagcgtgtgc ttgttatgga aagcgttgca gaccagctgg tagcagagat taagggctta
    21001 gttgagaaat tacttatcgg tatgccagag gacaatgctg acatcacacc attgattgat
    21061 accaaagcgg cagattttgt tgaaggtctg gttaatgatg cagcagacaa gggagcacag
    21121 gcgcttactg aaatcaagcg tgacggtaat ttaatttgtc ctatcttgtt tgatagagta
    21181 acaactgata tgcgcttggc ttgggaggag ccatttggtc cggtgctgcc agtgattcgt
    21241 gtaagctctg tagaagaggc aatcagcatt tcaaatcaat ctgaatacgg tttgcaagcg
    21301 tctatcttta cgactaattt tccacaggcc tttgctattg ctgagaagct tgaggttggt
    21361 acagtacaca ttaacaacaa aacccaacgt ggtacagata atttcccatt cctaggggct
    21421 aagaaatcag gagctggtgt tcaaggggtc aaatattcaa ttgaggcaat gacaagtctc
    21481 aaatcagtcg tatttgatat tcaataacaa aaaagctagg gtatcttagt ttgaaagcag
    21541 ttgcacattt gtgcggctgt tttatttgtg tctctagttt taacagctag ctatgcaaga
    21601 aggtgagttg tcccaacctc aaagatgaga tctaaatatt taatgatttt ggggtcgtaa
    21661 aaaagtttag agtgttttga tctccttaag atgtgagtgt acaaagtctc gccaacagcc
    21721 agcaggacta gccattgagg tcaaggaagc tgctaaaata gctgatggtt caaaagcttg
    21781 gtgaaaggct taatatctat cattgctatt ttgagggctt tccattataa tatgaatact
    21841 agagctactt gtcggtctgc ctcttgagct gtgagatagc tgttggattt agttgtctcc
    21901 ttgtccacaa aaggcttaga ggcaaaggct gtggctatgc ttcttgcttc ttttagtgaa
    21961 gtgtatgaga tcttatgaaa actcatatag gctttggtat ctttgcaaga ggactaatgg
    22021 cttgctttac ttgccttgat agagggctgg gattgagggg tgatgacctg cggtggtcat
    22081 ctctagagct ccttgcttct ttttttatgt agactaatgg tttagactgc tagcttcctt
    22141 gtttagaaag taggacatca tgttacccaa gagaaaatta attgatcaac gtcttgatta
    22201 tgccattatt tttcctgttt tttgtttgct aatatttggt ctggtatctg tatatgtggc
    22261 agcaagtcat gattttccgc aaagcctcgc cactgttatg cttcaacagg ttctctggat
    22321 ccttcttgga gctgtgattg cctttaccct aatgtttttt agcacagaga ttctgtggaa
    22381 attaacacct gtcttttatc ttttgggtgt gctattaatg gttctgccac tcatcttttt
    22441 tagccctcgg ctggtagctg ctacaggggc gaaaaattgg attacgattg gctcaacgac
    22501 cttgtttcaa ccatcagaat ttatgaaaat atcctacatt ctggcaatgt cttggttaac
    22561 ggtctggttt aagagaaagc aggagagaag tcggttttta gatgattgga agctcttggg
    22621 cttatacctt gtcttgacgt tgccggtcat ggtcctgcta gcactgcaaa aggacttagg
    22681 aacagctatg gtttttttag ccatcttagc tgggattatc ttaatttcag gaatttcttg
    22741 gtggcttatt ttaccagctt tggtactagt ctttttactg gtttcagctt ttttctttgt
    22801 ttttttgttg ccagagggaa aagaattcct tttaaaaatg ggaatggata cctaccaatt
    22861 gaatcgtatt tcagcttggc tgacaccgtt tgatttctca gataccattg cctatcagca
    22921 gacgcaaagt atgatttcga ttgggagtgg tggctttttt ggtaagggct ttaatcagct
    22981 tgagctgtca gtaccagtca gagaaagtga tatgattttt acagtgatcg ctgaaaattt
    23041 tggctttctt ggtgcagcta gcttactgat cttgtattta atactgattt accgcatgct
    23101 tagggtgacc tttgcatcga ataacctttt ttatacctac atttcaaccg gctttatcat
    23161 gatgatacta tttcatattt ttgaaaacat tggcgcagca gttggtctgc tacctttgac
    23221 cggtattccc cttcccttta tttctcaggg cggctcttcc ttgatttcaa atctgattgg
    23281 ggtcggcctg atcctatcaa tgaactatca gcacgtcctt gctcatgaaa agcaaagcga
    23341 gcatgagctt agcagaagct cacgttatgt ttaagaggca tgtttggtcc ttgttcggtt
    23401 agaatgagct gccaatcagc ccttttttat ttgcttaatc gctataaaaa taaagaaaaa
    23461 tatgttataa ttaaggttat gaattatcat gattatattt gggatttggg cggcactctc
    23521 ttggataact atgaaatttc tacccaggct tttattgaga cgctgcattt ttttaagctg
    23581 tctgcaagcc acgatgccgt ttatcaaagg cttaagaaat caacagcaac cgccattcaa
    23641 gtatttgctc ccaacgaacc gcaattttta caatattaca aagcgaatga ggctaagaaa
    23701 ttagccaatc ctatttggtg cctaggtgca aaggacattc taaagaggat tgtggcatca
    23761 ggctcgcgta attttttaat atcccatcgt gatcatcagg tcaatgattt gctggagcag
    23821 gctgggcttt tgggctattt taccgaggtt gttaccgcct caaatggctt tgccagaaag
    23881 cctaaccctg agagcttact ttatttgaag gaaaagtacc tgatcagcaa gggcttagtg
    23941 attggtgatc gcagacttga tatagaagca ggacaagcag caggctttga caccctgctt
    24001 gttgatggta gaaaaaacct attggagata gtagattaga tggttgaaga aaataaacaa
    24061 ttagaagaca aggctcaaga gtatgacgct agccagattc aggtcttaga ggggttagaa
    24121 gccgttcgca tgcgtcctgg aatgtatatt ggctcaactg ccaaggaagg cttacatcac
    24181 ctagtttggg agattgttga taattctatc gatgaagcct tggcaggctt tgccagtcat
    24241 attcaggttt ttattgaggc agataattcg attaccgtta ttgatgatgg acgtggtatc
    24301 ccagttgata ttcaagctaa gacaggccgg cctgctgtag agacagtttt tacagttttg
    24361 catgccggtg gaaaatttgg cggtggtggc tacaaggttt ctggaggact tcatggtgtt
    24421 ggctcctcgg ttgttaatgc cttatccaca cagcttgatg ttcgtgtcta taaaaatggg
    24481 catatccact atcaggagtt taggcgtggt gctgtagttg atgatttggc tatcattgga
    24541 acgactgatg ttacgggaac aacagtgcat ttcacacctg atccagagat ctttacagaa
    24601 acaacagaat ttgactacca ggtcctggca aagcgtattc aagagctggc ctttcttaat
    24661 cgtggcttaa aaatctcaat tacagataaa cgagctggtc ttgaaagaga agagcatttc
    24721 cattacgagg gtggtattgg ctcttatgtt gcctttttaa atgacaaaaa ggacgtcatc
    24781 ttcgatactc cgatttattc tgatggtgag ctggagggga taacagttga ggtggcgatg
    24841 cagtacacta caggttacca tgagactgtt atgagctttg ccaacaatat tcacacacat
    24901 gagggtggta cccatgagca gggctttaga acagctctga cgcgcgtgat taatgactat
    24961 gctaagaagg ctaagattct caaggaaaac gaggataatc tgacaggtga ggacgtccgc
    25021 gagggcttga ctgctgttat ttctgtcaag cacccaaatc cacaatttga agggcaaaca
    25081 aagacaaagt taggaaattc tgaggttgtt aagattacca atcgcttgtt tagcgaagct
    25141 cttcagcgct ttctactaga gaatccgcag gttgcccgta agattgttga aaaggggatt
    25201 ctagcctcta aggctcgcat tgctgccaag agagcgcgtg aagtaacccg caaaaaatca
    25261 ggcctagaga tttccaattt gccagggaag ctggctgact gctcctcaaa tgatgctagt
    25321 caaaatgagc tttttatcgt ggagggggat tcggctggtg gatcagcgaa gtcaggtcgc
    25381 aatcgtgagt ttcaggctat tctgcctatt cgtggtaaaa ttttaaacgt tgaaaaagca
    25441 acgatggata aaatccttgc taacgaagaa atcagaagcc tctttactgc tatggggaca
    25501 ggctttggag cggagtttga tgtttctaga gctcgctatc aaaagctggt catcatgact
    25561 gatgcagatg tcgatggagc tcatatcaga acgcttttgt taacgttgat ttatcgcttc
    25621 atgcgaccag tattagaggc tggctatgtt tacattgctc agccaccgat ttatggtgtt
    25681 aaggttggca gcgagattaa ggaatacatt caaccgggag tcaaccaaga agaggagcta
    25741 aaggctgctc ttgaaagaca tagcacagga cgctcaaggc cgactattca acgctataag
    25801 ggcctaggag agatggacga tcaccagctt tgggaaacaa caatggaccc tgataatcgt
    25861 ctaatggcac gtgtgaccgt agatgatgcg gcagaggctg atcggatttt tgacatgctg
    25921 atgggcgatc gtgttgagcc aaggcgtgaa tttattgagg aaaatgcggt ctatagtacg
    25981 cttgacattt agtcaaatat attttgaaaa gcacctaaaa gtatgttata atcgtaacgt
    26041 tatagtgtat ttttgataat ataataaaag gcgattcttg ctagttgttc ctactgaacc
    26101 ggcagttgat caatcgcatc taaataataa ggagattaag atgtcaagcg gaattatctt
    26161 gctgattgtg gccatagtct tactagtgat tattgcttat ttagtgggtg ttattatacg
    26221 caagcgtaat gacacattaa ttaccagtct agaagaacga aaacaagctt tatttggcct
    26281 tcctgttaat gacgaaatcg aggaagtcaa gtctcttcac ttgattggtc aaagccagac
    26341 ctcatttcgt gaatggaatc aaaagtgggt tgatttgacc ctaaatacct ttaccgatat
    26401 tgaaaagcat atctttgagg ctgagcactt aaatgacacc tttaatttca ttcgtgccaa
    26461 gcatgagatt aatagcgttg agagtcaatt gaatctcgtt gaagaggata ttaccgctat
    26521 tcgtgaagca cttggcatat taaaggagca ggaagaaaaa aacagcgcgc gtgttactca
    26581 tgcactagat ttgtacgaaa agttgcaggc ttccgttgct gaaaatgaag ataatttcgg
    26641 atcaacaatg gccgaaattg aaaagcaaat gaagaatatt gaagcagagt tttcacaatt
    26701 tgttgccctt aattcatcag gtgaccctgt tgaagcagcg gaggttttgg ataaggctga
    26761 ggagcatacg attgccttgg ggcaaattac agagcagatc cctgctattg tagcaaagct
    26821 tgaagatgat tttccggatc aattggacga tctggagaca ggctatcgtc gtttgctgga
    26881 ggaaaattat cacttcccag aaaaaaatat tgaagcccgc tttcaagaga ttcgtgagtc
    26941 tattcgtgcc aattcatcag agctggttac ccttgatttg gaccgagcta gagatgaaaa
    27001 tactcacatt caagagcgta tcgactcact gtatgagctc tttgagcgtg agattgcagc
    27061 ctacaaggtg gttgctaaaa atagcaaaat attaccaaga tacctggctc acgccaagca
    27121 caacaacgag cagttgaagc atgagattgc tcgtctatca cgtaagtata tcttgagtga
    27181 aaatgaaggc ttaaatatca aggcctttga caaagacctc aaagatatcg aagacaatgt
    27241 ccttgagatt gctgaagcct ttgatcagca ggaaaagcca ttttcagagc tacagctgat
    27301 tcttgatcgt agtatcaaga cgttggcttc tgtagagtct ggtcagatgg acgtctttgc
    27361 tgctgttaaa gacattgaaa agattgagtc acaggctcgc cagcacttag aaatctacgt
    27421 cacacagctt cacatgatta agcgttatat ggaaaagcgc aatttaccgg gaattccaca
    27481 ggattttctg agtaccttct ttaccactag ttcgcagcta gaagcattga tggacgaact
    27541 aagtagagga cgtatcaaca ttgaagcggt gtcccgtctg tctgaggtgg caacagctgc
    27601 tattgctaat ctagaagagc taacctacca agtggttcag catgctacct tgacagagca
    27661 gctgctccag tactctaacc gttatcgttc ctttgaagct ggcgtgcaaa atagctttga
    27721 gcatgccttg aaattgttcg aggtggacaa tgactatcag gcatcatttg atgagatttc
    27781 ctatgccttg gagacagtcg agccaggagt gacagagcgt tttgtcaatt cctatgagaa
    27841 gacacgtgaa cgtatccgct tctaatgtga caagggttga tactttatat tacgaaaaag
    27901 cttgaaaaag cagtccatgc tgggctatgc tttttcaagc tttttgaatg gtcaggctat
    27961 ggcctccttg agctataccc aaaaagctgg ttcaagccag tcagtagaga tagacaaggc
    28021 cttagtgcta ttgggctgtt gctacatgag atattttgta ataaaatcag acgattatcc
    28081 atttaattaa aaaaaaaaaa aacgaaactg cggaggaaac ctgacgagta actatttatg
    28141 gctatcaatc agcatgttac actctttttg gaaggcctag caatcactga ctgtgaggtt
    28201 aaccaaagaa aataagatgt taaggagaat atcaatgaaa ataactaaag cattgtgtgt
    28261 agcaggtgct gttgcagtcc tagccttggc accaatcagc tcaagtcctg caccaacaca
    28321 gactgtattt gctgctacac gtggtactga agagtactgt cataatgggt ggtgcagttt
    28381 tcttgatgaa catggtgagt ggaacacgaa acgtgagggc gaatctaata gtcccctaca
    28441 gcgaggttca tggtgggatt ggatttctta ttggtctggt tatatatggt attctgtata
    28501 taactggttt aggtaacctc tcaacgccac tgctaccata ctgataaatc ccttagacta
    28561 ttctaaggga tttttactgc aaaaagcaca tagggacaag gcaatacaag ctccagcctg
    28621 ttcttagctc cctataccgg taaggatcat aacactcaga actccggcag atgattgcag
    28681 gagctattgg agagtgagga ctagtgaaag agcctctgcc agagggattt gcccttagtc
    28741 tttgtttgtt cagcaggctt attgtcagag ggcttgtcta gtatagcctt gagattggtt
    28801 tcctctttgg tgatggcatg atcactatga atgatcagag caaaaggaga gacagctcct
    28861 ttctcatcta caatagtggc agatagagcg ttttgttggg ccaatttcat atagtacatt
    28921 tgataagcag agccgaattc agaggataat ttgaatgaca aggggaaata agcctctttg
    28981 aggtgaggca gctgggctgt gatgtagcct ttagcctttt catgatcaac ctctgtcaag
    29041 ggaagcgcta agacaatcct ttcagcatag gtccctaaat aatagcgttg ttggtcgggg
    29101 tcaaatcggt tttctcctga agctcccttt aagagtcttg tatctaatga atccatacaa
    29161 tcctttcaag catgtgatac tgtcattata ctattaactg cgccaaatac caatgataaa
    29221 gcatttacta ggtatttgat cggcttttgg aagaagatga aatcaaagaa aaacagcatg
    29281 aaaacaactc tcttatttca tgaaattagt ttttaagttg cttaagaccc tagtttgtgg
    29341 tattattaac atgtaaaata ttaaaactca taaggagagt attataatgt caattattac
    29401 tgatgtttac gctcgcgaag tccttgactc acgcggtaac ccaacacttg aagtggaagt
    29461 ttatactgaa tcaggtgctt tcggacgtgg tatggttcct tcaggagctt ctactggtga
    29521 gcatgaagca gtagaacttc gtgatggcga caaatctcgt taccttggtc ttggtactca
    29581 aaaggcagtt gacaacgtta acaacattat cgctgaagcg atcattggtt atgatgttcg
    29641 cgatcaacaa gctattgaca gagccatgat cgctcttgac ggtactccaa acaaaggtaa
    29701 gcttggtgct aatgctattc ttggtgtgtc tatcgctgta gcgcgtgctg ctgctgacta
    29761 ccttgaggtg ccactttaca cttaccttgg aggattcaat actaaggttc ttccaactcc
    29821 tatgatgaat attatcaacg gtggttctca ctcagacgct ccaattgctt tccaagagtt
    29881 catgattatg ccagttggtg cacctacctt caaagaaggt cttcgttggg gtgctgaggt
    29941 attccatgct cttaagaaaa tccttaaagc gcgtggactt gttactgctg ttggtgacga
    30001 aggtggattt gctcctaaat ttgaaggaac tgaagatggt gtagaaacaa tccttaaggc
    30061 tatcgaagct gctggctatg aagctggtga aaatggtatc atgattggtt ttgactgtgc
    30121 gtcatcagaa ttctacgata aagagcgcaa agtctacgac tacactaagt ttgaaggtga
    30181 aggcgctgct gttcgtacat ctgcagagca aattgactac cttgaagaat tggttaacaa
    30241 atacccaatt atcacaatcg aagacggtat ggacgaaaat gactgggaag gctggaaagc
    30301 acttactgag cgcctaggca aacgtgttca attggttggt gatgacttct tcgttacaaa
    30361 cactgaatac cttgctcgtg gtatcaaaga aggtgcagct aactcaatcc ttatcaaggt
    30421 taaccaaatc ggtactttga ctgaaacctt tgaagctatc gaaatggcta aggaagctgg
    30481 ctacactgct gttgtatcac accgctcagg tgaaactgaa gattcaacaa tcgctgacat
    30541 cgcagtggca acaaacgctg gccaaatcaa aacaggttca ttgtcacgta ctgaccgtat
    30601 cgctaaatac aaccaattgc ttcgcatcga agatcaactt ggtgaagttg cacaatacaa
    30661 agggatcaaa tcattctaca accttaaaaa ataatttgat tttagattaa aaggttgaca
    30721 agccttgatt ttaaagcatt ctaggactgt cctagagtgc ttttagtttt agcttcatgt
    30781 caactgtagt gggtgactga tagctaagca cgagaggaga cgaaggtcgc cttctctttt
    30841 tcaatcggat aaggctaggg aatccccaaa tgtcgatgaa gggaatttta gaaggtttct
    30901 ggaagtcgta tatgatttgt ttccctttgc agtgtctaca cctaggagac tgatagtcca
    30961 gtgtagcgct gacttcgata tgagtatcgt gctggatagt cttattcaag gtgatatttt
    31021 gatctttgat tccgatgagt agtgtggtat gatgaatctg ttccataaga cactttctaa
    31081 tgatggtctg gtcgcttttc atgataagcc ttatggaact ttttgggtac tcaaaaagcc
    31141 ctataatctt cataatgaat ttacccatta cagaaattat agagccaata tttagaggat
    31201 tttagcctat tggtagattg acagtttctt aagattgtgt tacaatgtaa cacaaagaaa
    31261 cgaggtaaac gactatgagt acagttacta tcagattaaa tcaagaagaa gaaatatttt
    31321 tcaaaagtta cgcccaactc acagggcaaa gtttatcaag tctatttaaa aaagcccttg
    31381 agcgggatat tgaagatgag tatgatttaa aaatctatca tcaagcctat gctgaatata
    31441 aagcagaccc tgagacaatt agccatgctg attttaagaa agagctaggc ttataacatg
    31501 taccgtatag agtattctaa aaaggctcaa aagcagatta agaaagtaga taagcaaatt
    31561 cagaggttgc tatttgcttg gattgataag tatttagagg gaacagataa cccacgcgca
    31621 aatggcaaag gtttgaccgg aaatcatgct aatgagtggc gttatcgtat tggtgattat
    31681 aggcttattt gtgatattca agatgataag atggttgttt tagcgcttga gtttgggcat
    31741 cgtaaagata tttactaacg ttgaggaagt aagatggtca aaaataatgc aattggtagc
    31801 aactggaaag atgtaagagc tgagttattc agcaaggaag aattttagaa agtgatgctc
    31861 gtattgctat tatggacaag tatagttaaa aagtgtgcgt ttttaatctg tatgatgaag
    31921 taattgataa agtaacaggt caaaaggcta tcattgtctg tattgctaat aaattggtag
    31981 atgattgtta tttaatcgaa ccgctaaacc attcttactt accagattgg cgtgagataa
    32041 atcagttaat tcgatataaa aattagcacc ttatcgggtg ctaattcctt gcctgctgaa
    32101 ctcataattt aatacctttt ttactacccc atatgtttcc cctaattatg tgtacttgct
    32161 agatataagg ttaattggga tagaattttg aataaagttg ttgtattttg taatagtgat
    32221 tgatattggg ataaccttaa aaaaataatt tgattttaga ttaaaaggtt tacaagcttt
    32281 gattttaaag cattctagga ctgtcctaga atgcttttag ttttgataag cacaatccgc
    32341 tgttgactgt ataaaccgta tatgatacaa aataagagct tgtagcagtg aagccactaa
    32401 ctctagtgct gtgggctcaa ccttgattga tgaatccctt gcttttaatg cgtttatgaa
    32461 gcagtggcgt atcagtctag ctcgttgtgg aaagcaatta actagagaag aattactatc
    32521 ctcaatcaat atgctgacag ccgcagggat ttgtgagttt gatttgctgt ggcagcgtct
    32581 tgctcctaag gggtgtcagc gtcccaaatg gagccatcag ctggagaggc tctttgcgga
    32641 tacaaagcct tgtctacagg tcttgtctga gacttatcag cttgggatta ttgctaatca
    32701 ggcaaagggt ctaaaagagc gcttagagag gtttgggatt agtcattatt ttgcccttat
    32761 gatatcttct tctgatgtgg ggctacaaaa gcctgatctt gctctgtttc gctatgcact
    32821 tgatcaagca ggcgtattag cgcgtgatgc tgtttatatt ggggatcgtg ttgacaatga
    32881 tattattcct gctaaggcat tgggaatgag agctgtcagg attcatcaag ggcttgctgc
    32941 gtccagtcca gatgataggc tttatcctag tgatgtccat attagcaaac ttagtgacct
    33001 gttagaatgc ttttaaccag tctttagctt gaactagctt ttctttgtgg tctttctggg
    33061 tgaatggcag caagctttgg agtcatgtta tggctagacc ttggatctaa gggcgctgag
    33121 cgtctcatat gatgaggccg atcaagtagt ctccttgaca agtagattat tgtttggtgc
    33181 ttataggtgg ctttaggtga tgactggttt tgcctcaact aaggctcgct attgctatct
    33241 ggggtatctt ctgacttttt taatgtgctc ttatctggtt ggattagacc tgctccttgc
    33301 ttgaggaaag ctgtttttaa cgctgatgag tctgggaaat ggtgagattg gtgttggctt
    33361 ttactagttt ttttgcgttt acttgggcta actttatatg agaaaaaaag aaaaatattt
    33421 attttatctg ttatttttgt tacaataagc gtgtaaacta agatgcatta aaaaggagtt
    33481 tttatgtcga ataagaaatt ttttacttat gcttcattat tggcattaat cgctgttcct
    33541 actgtggttg aagaggtgac tgcacagcct tcagctcagc ttgtttatgc agatgagcta
    33601 aggctatcac caagtaccga ctcatctcca gtaacaaaga ccgatgaggc tgatcagcca
    33661 gttgctcaat ctgtttctgc gacagaacca gtagaggctc ttgttattgc ggataaagaa
    33721 agcgctttaa atcctgctgt tctagctgat gccgatggaa gtcagccgat tgcagtggtt
    33781 agagctggtc aagagggtca gccttatacc gttactggca aaatcatcag tgctgttaat
    33841 ggctggggtg gtcatggctt ttatatccag gacagtcagg gatcaggtct ttacatttat
    33901 ccaggaagtg ctttggggta cgtgactggt gatgtggtgc agctgacagg aacactgact
    33961 acttacaagg gtgagcttca gcttaaaacg attacaaagc atcataagat taatggcgaa
    34021 ttaccaacac ctattgctga ggtaaccatt ccggagctag aaaaagcaag cccgtctacc
    34081 ctggtgaagc tttcaaatgt gactgttgga gacatttcat cagataagca cgaaacctcc
    34141 tcttttaagg tcagcgatac agctggcaat agtgttgcgg tgcgtcttga taatcgtaca
    34201 ggtgttaaga cctctgactt actctctaaa attggcaagg gtgatgtgat taatctgaca
    34261 gctattcact caacctttga tgggaagctc cagctcaagc cctttagcct tgagcaattt
    34321 gaggtagtaa agaaggttgt tcgagaagaa gaggtgactc ctcttggtcg agtggttaaa
    34381 atcggccaaa ttcaaggtgc cagccacacc tcaccgctct tgaatcaagc tgtaacagta
    34441 aaagaggtgg tggtgaccta tcctgatgat gcaactcatt tctatgtgca agatattaat
    34501 ggtgacaacg ataaggcgac ctcagacggt attcgtgtct ttgctcaaaa tgctcaggtg
    34561 caggctggtg atgtgctgac catttccgga acagtggagg agttctttgg caaaggctac
    34621 gatgaccgta agcagacgga tctgaccatt acgcaaatca aggcatctaa ggtcactaaa
    34681 acagggactg ctcaggtacc agctccgctt gtgctaggta aggatcgtgt tgctccagct
    34741 aatatcattg ataatgatgg ctttagtgtt tttgatccag aagaggacgc tattgatttt
    34801 tgggaatcct tggagggaat gcttgttgcc gttgataatg ccaagatttt agggccgatg
    34861 tctcataagg aaatttatgt gttaccaggg tcatcaactc gagtgctgac taactcaggt
    34921 ggtattttac ttcctgagac aggctataat acagacctga ttcctgttct ctttaaaaaa
    34981 ggaaagcaaa ccatcaaagc tggtgattcc tatcagggac gacttgcagg tccggtatca
    35041 tatagctatg gtaattataa ggtgtttgtc gatgacagca gtcgtatgcc agtcttggtt
    35101 gatggtcagc tgaagcctga aaagacacac atcaagaagg accttagcaa gctaagcatt
    35161 gcctcataca acattgaaaa cttctcagca aacccatcat caacaaaaga cgagaaggta
    35221 aggcgcattg cagaatcctt catctatgac ctaaatgctc ctgatattat tggtctcatc
    35281 gaggttcagg acaataatgg acctactgat gatggcacaa cagatgcaac acaaagcgct
    35341 cagcgcttga ttgatgccat caaggcctta ggtggaccag cttatcaata tgtggatatt
    35401 gctccggaaa ataacgctga tggtgggcag ccgggcagta atattcggac aggcttcctg
    35461 tatcagccag gacgtgtcag cctttctgat aagcctagag gtggtgttaa tgatgcggtg
    35521 aaatgggtaa atggtgagct aagcttgagt gttggacgta ttgacccaac aaatcctgct
    35581 tggaatagtg ttagaaaatc attggctgct gagtttattt tccaaggcca caaggttgtg
    35641 gtggttgcca atcatttgaa ttccaaacga ggcgacaatt cattatatgg acgtgttcag
    35701 ccggtaacct ttaaatcaga ggaaagacgt catgtcttag caaggctttt gagccaattt
    35761 actaaggaag gtgctagtca gcaggctaat atcgttatgt tgggtgactt taacgattat
    35821 gagtttacga agaccattaa gctgattgaa gaaggagata tggcaaattt ggtgagcagg
    35881 catgagcttt ctgaccgtta ttcttacttc tatagaggaa ataaccaaac gcttgataac
    35941 atgcttgttt cacgcaattt gcttggtcgc tacgagtttg acatggttca tgtgaattca
    36001 ccatttatgg aagcgcatgg acgtgcttct gatcatgatc cgttgcttct tcagctctcc
    36061 tttggaaaag acaagccagc agcaccatca gatcagccaa agaaaacacc agcaccagct
    36121 gcgacaactc aagcctctaa ggcaggacgt gcacagctat tgccaaaaac aggtgataag
    36181 acagcgctta tggtaagtat tttaggctta acagctgtct ttagctcctt tagcctgttt
    36241 aggaaatgtc aggaaaggaa gtaaaggatt tctttggggt aggccagcag ctgagcggct
    36301 actgcgtttt gtctgctggt gctatatagg tggttgaagc gagcgaagag aggtatgctt
    36361 cctaggatca tagcacaata tcttatgctt ataaacgaac acaatgctcc ttatgagcat
    36421 tcaaaaccta tactcaaaag gaatataaca gctgagttaa gagggattgc ttttgacaga
    36481 ttgtggtaaa aaaagggatc ttgaggaatt ggctagtgat ctagctgcca aaatgcgatg
    36541 tcttgtttga ctatttttcc ctattgggat ataatgacaa tagaaaaagg gtagttgttt
    36601 gcgcaactac cctgtgcaga accgtttaag acggtggcag aatgaaagtt aaaaaataat
    36661 cgtcgaccta ccaaagttca gacggttatt ttttattgtt taatatgacg attgcaacga
    36721 ctaagctgat taaggtaagt aagaaactac caaaagccag catgagttga agggcctcgt
    36781 aagtagacaa taaaacgctc ctttcagttg gattttgatg cattgcccat aggcatcacc
    36841 acctttcaga aatcagagcc accgtcttag cttttctgta aagaacatta tatcataatc
    36901 acatgagaaa gccgttagat tttaaactga tcaggcggct ttttggtgtt ttgctgtctt
    36961 ttagtggaat cgcctaagct ttgctgtata gtatgggatt ttatgctttt tgtaagggct
    37021 taggctgcta tggcagggtc catgtccttt gtcaatagct tagttttatg gtacaatgta
    37081 ggcgttgcct agcaaccctt ggtgcttagt tccctttcac caagcatatt acaaacgtgg
    37141 cggagctgtt tatgctctag tctgacgtca aaggagaaac acatgacaag ttttactgtt
    37201 cgtgactatg tttacattgc tctagtggct gccctttatg tggttttgac aatcactcca
    37261 cctttgaatg ctatttccta tggcatgtat caatttcggg ttgccgagat gatgaatttt
    37321 ttggcttttt accataaaaa gtatatcatt gcggtgacct tgggctgtat gattgctaat
    37381 ttttatagct ttggcttgat tgatgttttg gtgggtggag gctcaacgct catttttgtt
    37441 agcttaggtg tcgctttatt taagcaatac caagaggaat atctcttaaa tggcttgctg
    37501 aataaggcct ttgtttattt ctcactattt tttgcgactt ctatgatcac cgttgcgatt
    37561 gagctttact tctttggagc accatttttc ctaacttggt ttaccactgc tgtaggggaa
    37621 tttgcttcac ttatcattgg ctctatgatc attgatcgct tatcaaaacg cattaattta
    37681 cgacaataat agtaacatgt agccttccgt ttttgggagg ctttttatga ttttcttcta
    37741 gctaggcaat agcttatttg ctatgttttg tgataaaata agactatgaa aaaacgcata
    37801 agagaattga ctgatctgtt aaatcaatac cgtcaggagt attacaccaa tgacgctcct
    37861 tctgtatctg atagtgagta tgataagctt tatcgtgagc ttgtagagct ggagcagacc
    37921 tatccagcct atatcctaaa ggacagcccc acacagctgg tgggcagtac gattttgaca
    37981 ggatttcaga aatatcagca ccagtatccg ctctttagtt tgcaggatgc tttttcacgt
    38041 gaagagctta acgcctttga tcagcggatc aaatcagcct ttcctgaggc tgaatacctt
    38101 gctgagctaa aaattgatgg cttgtccatt tcgctggttt atgaggctgg tgttctaaag
    38161 gttggagcga cacgtggcga tgggactatt ggcgagaata tcactgaaaa cattaagaat
    38221 attaaggata ttcccaaacg gctaagtcaa gcacttgatg tgacgatacg gggggaggcc
    38281 tatatgtcgc gtcaggcctt taagacgatc aatgaagagc gtcaggaaaa tggtgagcca
    38341 gaatttgcca atccaagaaa tgcagcggca ggaaccttga ggcagctgga tactaggatt
    38401 gttgccaagc gacagctagc aacctttttg tatcaggagg taggcctaga aactgctgat
    38461 agccagcaaa agaccttgga gcgcttggcc gatttaggct tttcggtcaa tagccactat
    38521 ctgctgtcct catcgatgaa tgacatttgg gactttatcc agagcattga agctagtaga
    38581 gaagagctac cttatgagat tgatggtgtg gtggtcaagg ttaatcagtt ggcgatccaa
    38641 gaggaacttg gctttaccgt caaggcacca cgctgggcta ttgcttataa gtttccagca
    38701 gaagaaaagg aagctgagat tgtatctgtg gattggacgg ttggccgaac aggtgtggtc
    38761 acaccaacag ctaatttgac ccctgtgcag ctggcaggca ccactgtcag tcgagcgacc
    38821 ttgcataatg ttgattatat cgcagaaaag gatattcgca ttggggatac ggtggtggtg
    38881 tataaggctg gagatattat tccagctgtt ttgcgggtgg ttgaggctaa gcgtagggat
    38941 caggctccaa tgcccattcc tacagcctgt ccttcctgcc agagtcagct ggtgcatttt
    39001 gaggacgagg tagctttgcg ttgcattaac cccttgtgtc cgagcttggt tcaacggagc
    39061 ttggagcatt ttgccagtcg tcaggcgatg aatatcgctg gtcttggtcc agcggttgtt
    39121 gaaaagcttt attctgctgg cctggtgcat gatgtggcag atatttaccg actaagcttg
    39181 gaggatttgc tgacgctaga tggtatcaag gaaaagtcgg ctgaaaagct cttggcagct
    39241 attgaacaat caaaggcaaa ctcagctgaa aagctcttgt ttggacttgg tattcgtcat
    39301 attggcgcaa aggctagtcg tctgatatta gaggcttacg gtgatttaga ggcgctgtta
    39361 gctgtaaccg ctgaagagct cgctcagatt gacgggcttg gtctagtgat cggacaatcc
    39421 ctggtgcagt attttcagca agagcaagcc gctcagctgc tagctgaatt aaaatcagct
    39481 ggggttaatc tggcttattt aggccaaagg cctgatcaac aggctgcgct gtttggttta
    39541 acggtggtat tgacaggaaa attagaaaag ctaaaccgta cccaagccat ggaaaagcta
    39601 gagcagcttg gtgctaaggt aacaggaagc gtttctaaaa aaacagattt agtggttgct
    39661 ggcagcgagg caggctctaa gctggctaag gcccagcagc tgggtatcag aattgaagat
    39721 gaggattggt tgctcaatct ttagtgaggt aataacatga aaaaacaaat gagggctcgt
    39781 ctgatttaca atccaacctc tggtcaagaa atcatgaaaa aaaacgttgc agaggtgctg
    39841 gatattttgg aaggctttgg ctatgaaacc tctgcctttc aaacgacagc agctaagcac
    39901 tcagccttaa aggaagcaag aagggcagct aaagcaggct ttgacctctt gattgctgct
    39961 ggtggagatg gtacgatcaa cgaagtagtc aatggcattg ctcccctaga gaaaagacct
    40021 aagatggcga ttattccagc aggaaccacc aatgattttg ctagggcctt aaaggtacca
    40081 agaggcaatc ccgttgaggc cgctaagctg attggtaaaa atcaaaccat ccgcatggat
    40141 ataggacgtg ctaaaaagga tacttatttt atcaacattt cagccgcagg aagcctgaca
    40201 gagctgacct atagtgtccc tagtcagctc aaaaccatgt ttggctacct ggcttatctg
    40261 gctaagggag tggagctctt gcctcgagtg agtaatgttc cggtgaaaat cacgcatgat
    40321 catggcattt ttgagggaga ggtatcaatg atttttgcag ccatcactaa ttctgttggt
    40381 ggctttgaaa agattgcccc agatgctaag ctagatgatg gcatgtttac ccttattttg
    40441 attaaaacag ccaacctgtt tgaaattgtg cacctgctgc ggttgatcat tgacggtggt
    40501 aagcatgtta cggatcgccg cgtcgaatac attaaaacca gtaaaatcac cattgagccc
    40561 caatcagata agcgcatgat gattaattta gatggtgaat atggtggtga tgcgccaatt
    40621 accctagaaa acttaaaaaa tcacatcacc ttttttgcaa atactgattt gatttcagat
    40681 gatgcccttg tcctagacca agaggagctg gaaatcgaag aaatggtcaa gaaatttgcg
    40741 catgaggtag aggatttaga gcagggattg gaggaatagg gctagttatg gataatgcag
    40801 ttattgttca ttatcatagt tgcaagggac attattttca attaagtcta tggcaatggc
    40861 gagatggtaa gctgggcaag gacgcttatt tttcgaggtt tgacagcttt ggagcagttg
    40921 cttatctcac ttatccagca ccttattttt tgagtcatgc ttatgtgatt gtaaaggatc
    40981 agttttggca gcatcaaacc gttgattttc ggattgagcg tgattatggg gttccaaaga
    41041 ctgaggtgtg gcttgttgat ggtgatccta cggtttatta ttcgagacag gctgctgtgg
    41101 ctagtcgaca tgatggtaga tgtgatgtgc atgcctttga tatggctgtc aatagtcagg
    41161 cctttgacaa gcgctggggc tttagtggct ggctaggctt tcgctatcag cctgaggaga
    41221 cgtcttttcg tttgtgggct ccaacagcag aaaaggttga gctcattctc tatgcttcga
    41281 ctgatgagag agctagtgtt gccaaggttt tgcccatgca gcgtgggcag cagtactcgc
    41341 cagatcatca tgcagaaaac acatgtggtg tgtgggacat cagcctaaga ggtgattata
    41401 attaccatgc ttattgctac cgggtttatt atcgcaggcg tacctttaga gacactaggg
    41461 atccttatgc gatcgcaacg acagcaaatg gcaaaaggtc aattgtcatt gcaccggagc
    41521 atttaagacc gcagggcttt tcagtgaagc agggtaagga ggctacctgg cgcttagaca
    41581 atcctaatca ggcggtgatc tatgaaatgc atgttcgcga cttttcaaaa tcagaaacct
    41641 cgggcgttag cttggctaat cgtggcaaat ttaaggggct gattgagaca ggcacgcgca
    41701 atgcttttgg agattcaacc tgctttgatt atgtcaagtc ccttggcatt acgcatattc
    41761 agctccagcc ggtctttgac catcatcaat tctttgatga aaatggagat tatgcctata
    41821 attggggcta tgaccctgaa aattacaatg ttccagcagc cagctttacc agtaatccgc
    41881 atgagccagc tacccgtatc ctggaattaa aggaggtcat tcaggcttat catgatgcag
    41941 gcatcaatgt gatcatggac gtggtgtaca atcataccta ctcatcaaga gagtcagcct
    42001 ttcagctgac ggttccggat tattattacc gtatgaatcc taatggctcc tttcaaaatg
    42061 gctctggctg tggcaatgaa acggctagtg aaaaggaaat gtatcgcaaa tacatgcttg
    42121 attcgatcct atattggacc aatgagttta acattgatgg cttcaggttt gatctgatgg
    42181 gcttacacga tattgacacc atgaatctta tccgacaaga gctagataag attgacccaa
    42241 ggatacttgt ttttggtgag ggctgggata tgggagttgg tctggcagct gagcagaagg
    42301 ctaaaaaagg aaatgccagc caaatgcctg gaatcggctt tattaatgat gatcagcgta
    42361 atgcagttaa gggggcagag gtctatggga gcttagagaa gggctttgta tcaggtgcac
    42421 cgacagaagg acttgtagcc aagtctattt tgggcagtga tgagctggtc tcttattgta
    42481 cgcctagtca ggtgatcaat tatgttgaag ctcatgacaa ctataacctc aatgatttgc
    42541 tgtgggtttt gaatccagag gacagcaagc aggatcatgt caaacgggtt cagctagctt
    42601 cagctatgac gattctcatg caagggattt actttatgca gctgggtcag gaatttttac
    42661 gaacaaagct ttacccaaca ggtcaggata aggagctgac acaggcagac cgagaaaggg
    42721 cgatgaattc ctacaatgca cctgacaatg tgaatcaggt tgactggaga caggttagct
    42781 tggagcgcga aacggttgct attatgaaaa aactaatcta tctgaaaact aaaacagctt
    42841 tgttttcata cccatcattt gagcaaatca gacagcatgt ttacattgag catgctggtg
    42901 aaaatacggg cttcattagc tttacagtag aagatgaaag aaagtatcga ttgattttct
    42961 ctagttttag aaaccgcttg caatcatctg ctaatcatgt tataattgaa acaaatgata
    43021 agcgctttca agatagtgag tccatgctag atgagctgac agcgatgatc cttgacatca
    43081 cacaatagcc tgagtgttct caggttattt ttgtttgttg tcaaggataa aagggctgta
    43141 gttacagtta gcagagacct attaggacct tgcttatcat atcgcttagc gccttgaaaa
    43201 agggtttagg agtagggaaa gaagaggtga tgggatggat aatgacttag cgctttatac
    43261 ctttggcaca ggtgagaatt ttcacataca ggattatcta ggtgttcatc ggattaacaa
    43321 tgacacaggc accagctatg tctttagggt atgggcgccc aatgcagagg ctgtcagctt
    43381 gattggagat tttactgatt ggcagtccaa tccacttgag atgagccgaa atgaggctgg
    43441 cgtgtgggag gttaccacta gcttgccgca ggaaggagat atttataagt attgggttag
    43501 gcgccaaggt ggtcagcttg ttgaaaaaat tgatccagtg gcctttctat ttgaagctag
    43561 accaggaacg ggtgctattg tcaaaaccct tccagccaaa aaatggcgtg atagcttatg
    43621 gatgggacgg cgaaagcgtt ttggctttag gcagcgtccg gttaatatct atgaggttca
    43681 tgcccattca tggaaaaaag acgaaaacgc aaggccctat gactttagca agctaaaaga
    43741 agagctcatt ccctatctca agagcatgca ctacactcat gttgagttta tgccggtcat
    43801 ggctcacccc ttagatatga gctggggcta tcagctgatg ggctactttg cctttgagtc
    43861 aacctttgga agcccagaag cctttcagga ttttgttgag gcctgtcatc ttaataatat
    43921 tggtgttttg attgattggg tgccgggaca ttttacacaa aatgatgacg ccttagctta
    43981 ttttgacggt acagctacct atgaatatca ggatcaccat cgtgctcata attatggctg
    44041 ggggccctaa attttgattt gggtaaaact caggtacagt cctttttgat ttcaagtgcc
    44101 cttttttggc tggaggctta tcatgttgac ggcattcgag tagatgctgt tagcaatatg
    44161 ctttacttgg attatgatca aggcccttgg actccgaatc aatacggtgg caaccaaaac
    44221 cttgagggga tagcctttct tcaaaaatta accacagtta tcaaggaaaa acaccctgat
    44281 gtgatgatga ttgcagagga ggcgacctca gctaccccaa taaccagccc tgttgcagaa
    44341 gggggactag gctttgatta taagtggaat atgggctgga tgaatgatat tcttaggttt
    44401 tacgaagagg atccttatta ccgaaaatac gatttcaatc tcttgacctt tagctttatg
    44461 tattgcttta aggagcatta cattttaccc ttttctcacg atgaggttgt tcatggcaaa
    44521 aaaagcctca tgcataaaat gtggggggac cgctacaatc aatttgcagg cctaagaaat
    44581 ctttacacct atcaaatctg ccacccaggc aagaagctgc tttttatggg atctgagttt
    44641 ggacagtttt tggaatggaa atacgatcat caattagagt ggcaaaattt agaggacgag
    44701 ctcaatgcca aaatgcagca tttcacagcc agcctaaatc agctatataa ggaccatagc
    44761 atgctgtggc aaaatgatga aacctatgac ggcattgata ttattgatgc agacaataag
    44821 gacgaatcag tcttgtcgtt ttgtcgtcaa aacaataaag gagagctcct gctttgtgtc
    44881 tttaacatga cacctgttga aagaccaggc tttaccatag gtgtgccgat agcaggtctt
    44941 tatcaagaaa ttttcaatac agagcttgag gcctttggag gtgtctggaa ggagcacaat
    45001 cccttaacca acacagtagc caagaaatgg aagacttatc cgcagacctt gagctttacc
    45061 ctgcctgcac taggagcaag catctggaaa atcaagcgtc gtcagaagca ataagctatt
    45121 cattgcttac ttagctgttt caaccaaaag aagtcactac agtcatgaaa ggataacgaa
    45181 atgaagaatg gaatgttagc cctcatatta gcagggggac aaggaactcg cttaggaaaa
    45241 ttgacacaga gcattgcaaa gcctgctgtg caatttggag gtcggtatcg tatcattgat
    45301 tttgccctat ccaattgtgc taactcaggg attcataatg tgggggttat cacccagtac
    45361 cagcctcttg ccttaaataa tcatattggc aatggttcgt catggggctt agatggtatt
    45421 aattctggcg ctacgatttt acagccctac tctgcaacag agggaaatcg ctggtttcaa
    45481 ggaactagcc atgctatcta tcaaaatatt gattatattg atagcattaa ccctgaatat
    45541 gtgctgatcc tgtctggtga tcatatttac aaaatggact atgatgacat gcttcagacg
    45601 cataaggcta atatggctag cttgactgtt gctgtgattg atgttcctct aaaggaagcc
    45661 agtcgatttg gcattatgaa cacagatacc aatgaccgca ttgtcgaatt tgaagaaaag
    45721 cctgccaatc caaaatcaac caaggcttca atgggtattt atatctttaa ttggcagcgc
    45781 cttcggacca tgctggttga cgcagaaaaa aacaacattg atatgtctga ctttggtcag
    45841 catgtgattc cgtcttacct tgagtctggc gagcgtgtct acacctataa ctttaaaggc
    45901 tactggaagg acgtcggaac gattgagtct ctctgggaag ccaatatgga atacatcggt
    45961 gaggaaaatg ccctagacag tcgtgatcgt tcttggaaga tttattctaa aaaccatatc
    46021 gctccaccaa actttatcac agaggacgcc gaggtcaagg attctctggt agtagatggc
    46081 agctttatct ctggtaaggt caaccattct atcttgtcta ccaatgtgca ggtaagaaag
    46141 ggagccgagg ttaaggattc ctttatcatg agcgatgtta tcattggtga gggtgcaagg
    46201 attacacgag ctattattgg tgagggtgca gtcattggtg atcatgtgat cattgatggc
    46261 agcaaggacg ttcaagtcgt aggctataat gaagtagtgg gggtaccaaa tgaagattga
    46321 taaatattct gccattctag gcagctcaat tggctttgct gaaatgaagg ggctaacaga
    46381 cacaagacca ttagccaacc taccctttga tgggaaatac cggctcattg attttcaatt
    46441 gtccaacctt gccaatgcag gtgtccgtag catctatggt atttttcgtg ggcaaaatat
    46501 ccgctcagtg tttgatcata tcaggtcagg tcgtgaatgg gggcttaatt ccttactaag
    46561 tcattatttc cttggctttt ataacaccaa ggaggattct aaagaggctg acaaggacta
    46621 ttatcagcag attttgacct atttaaagcg ctcagggtca gatcagacca tttacatgag
    46681 ctgtgatatt ctctgcaata ttgagcttgg gcaggttatt catctgcaca atgccaacca
    46741 tcgcaacatt acggttgtct acaagaaaat gccgaccaag gccatctcta aggctaacga
    46801 tattttagat attgacgaga cagatactgt tgttgacagg cgaagtctgt ctgaggggca
    46861 ggaggttgaa aaaatgtcag caggcattta catcgtcaat accccatggt taattgaaca
    46921 gatggaaaaa gaagccgaaa aagaaaaccc tcaaaagcta cgcttcctct tacgtgattt
    46981 gattgtgtca gagggcgctc ttggctttga atatactggc tatcttgcca atattcactc
    47041 tgttaaatct tattttgatg ccaatatgga catgctggat ccgcataagt tttattcact
    47101 attatatgct aatcagaagg tctacacgcg tgtcaaaaat gaagagtcaa cctattttga
    47161 tgcggcttct gaggtgaaca atgcccaatt tgcttcagga agcattgtca agggctatgt
    47221 cgagcactca attgtctctc gcaattgtcg cattacctca caggcacgtg ttacaaatag
    47281 tattttattg ccaaaggcag tgattggtga gggtgctgtc attgattatg ctatcattga
    47341 taaatccgta agggttgcac caggtgttac tattagagga agcgctgagg agccaatagt
    47401 tgttgccaag gggactgagg ttgttgagga tatgataaaa tgaagataat gtttgttgca
    47461 gcagagggag ctccctttgc taagacaggt ggcctaggcg atgtcattgg ggcattgcct
    47521 aaatcacttg ttaaaaatgg tcatgaggtg tctgtgatac tgccttatta tgacgtggtt
    47581 gatcaagcct ttggtcagca ggttgaggac gtcttgtatt tttatacgca ggttggctgg
    47641 agacgccaat acgtgggcat taaaaagctt gtcaaggata aggtgacctt ttactttatt
    47701 gacaatcaag gttatttctt tagaggcagg atctatggtg attgggacga cggtgagcgc
    47761 tttgcctatt tccagctggc tgccatagaa gcaatggaga aaatcggggt tattccagat
    47821 attttgcatg tgcatgatta ccataccgct atgattcctt tcctattgaa agaaaaatac
    47881 cattggattc aggcctatca agcgattcgg acagttttta ccattcataa tatcgcattt
    47941 caagggcagt ttgatcctgg catgctaggc gatttgtttg atgttggtat agagcgctac
    48001 gaggatggca ccctgcgttg gcatgattgc ttgaattgga tgaaagcagc agtcctatat
    48061 gcagatcggg taaccactgt ctcaccctct tatgcgcatg aaattcagac accagccttt
    48121 ggacaaggct tggatcaagt catgcgaatg gaggcaggca agctatcagg cattgtgaat
    48181 ggtattgaca ctgacttatt taacccagca agggatcctc atttgcctgc ttcattttca
    48241 gcagaagacc tatcaggcaa ggcggctact aaacaggcct tgcaggagcg gttaggatta
    48301 ccagtcaggg cagatgttcc attgattggt atggtttcgc gcttgacgga tcaaaagggc
    48361 tttcagcttg ttcttgagga attaccgcat atcttgcagc aggacgttca gcttgtcttg
    48421 ttaggaacag gtgaccctga ttatgaggct gccttttcat ggtttgccaa ggcctatcca
    48481 gaaaaactgt ctgctaatat tacctttgat ctgccattag ctcagcagat ttatggggcc
    48541 tgtgatctct ttttaatgcc aagtgctttt gagccctgcg gactttcgca aatgatggct
    48601 atgagatatg gcgcgatacc gattgtccat gagatcggcg gcttgaagga tactgttgcc
    48661 tcctacaatg cttatgaaaa gactggaact ggttttggct ttgatcagtt ttcaggattt
    48721 tggttaacgc agacgctctt gtttgccctt gatatttacc ataaccacaa ggaggattgg
    48781 cagactattc aacaacatgc catgaccaag gatttttcat gggatacagc cagtctggcc
    48841 taccttgatt tatataaaag cttactataa cacagaaaag gaatgggaat gcacgtcaca
    48901 aaagaacaat ttattcgaga ttttaaagat accttacatg aggaacaatt gatcaaggtt
    48961 cctgccgcaa cagctgctga gcttttcacc tcattagcaa agcttatccg taaatactat
    49021 acagatactt ggattgaaag gaatcgttcc ttaaccgaac agcagcaaaa aattgcctat
    49081 tatttttcga tcgaattttt accaggaaga atgctagaaa caaatcttct taatttaggc
    49141 attcttgata cagttaaaga agcctttgct gacttgggaa ttgattttca agcagtgaag
    49201 catgcagagc acgacatggc tctaggcaat ggaggtctag gacgtttggc agctgccttt
    49261 atggattcgc tagcgacaac aggctatcca ggctttggaa atgggctgcg ttatcgttat
    49321 gggctgttta agcaacggat tgtgaatggt tatcaggtag aattaccaga ttcttggttt
    49381 ggctctattg gtaatgtctg ggagatcaga aaggatcatg acattgtaga cgtcaagctc
    49441 tttgggaatg tttacctaaa agccaatcag gacggtaagc tagcgccaat ctatgaggga
    49501 gctcaggttt tgagagctgt tccctacgat gttcctcaga ttggctttga aaatgatgtg
    49561 attaacaatc ttcgcctctg ggacgtagaa atcccagaag aacatgagct tgattaccca
    49621 accatcgagt caagacgggc agtcaaggac attactgcca ttttgtaccc agacgacagc
    49681 agctatgaag gcaaaaagct tagattgatc caagaatatt tcatgaccag cgcaggcatc
    49741 caaaccatta tcaaatccta tttaaagcag ggcttgccac ttactgagct tcatcaaaag
    49801 gtatctgttc atatcaatga tacccaccca gcagtagctc cagcagagct tatgcggctc
    49861 ttgattgacg actatggctt agaatgggta gacgcctggg cgacaaccgt aaaaaccatg
    49921 agctatacca atcatacgat tttgtcagaa gccttagaaa aatgggacgc agagctcttt
    49981 aagactgtgc tgccccgcgt ttatcaaatc attttagaga ttgatcatcg ctttgttgct
    50041 gaaatggcgc aaaagggtat tgatcctcag atcattgaaa acactagaat cgttaaggac
    50101 aaccagattt atatggctaa tcttgccatt attggtggct attcggtcaa tggcgttgcc
    50161 aagctacata cagagttgtt aaagacagat acccttaagg acttttatgc cttgtatcct
    50221 gaaaaattca acaacaaaac caatggtatc gtgcaaagac gttggacaca gattgctgcg
    50281 ccagagctat cagcagctat tgaccgcacg attggcaaag gctggcgcaa ggatattcac
    50341 cagcttcgac aattgagtca atttacagaa gatccagctg tgctaaatga tttttatcag
    50401 gtaaaacaag cagctaagca gcgcctagcc aggtatatcc tggaaaaaac aggtcttgag
    50461 gtttcaacag aggctatttt tgatgtgcag gtcaaacgcc tacatgccta caagcggcag
    50521 ctcctgaacg tcctgcatat tatgaagctt taccttgatt tgaaggctaa tccagattta
    50581 gatatggtgc ctagagtctt tattttcggc gcaaaggctg caccaggcta tcattttgcc
    50641 aagtcggtga tcaaaatcat caatgagctg gctaatctca ttaaccatga taccagtctc
    50701 aaaggaaagc taaaggttgt ttttcttgaa aattataacg tgagtctagc agagctcatt
    50761 atccctgcgg cagatatttc agagcagatt tcactggcct ccaaggaagc ctcaggaaca
    50821 tcaaacatga aatttatgat gactggtgct atcaccctag cgacccttga tggggcaaac
    50881 attgaaatca aagacgaggt cggagaggaa aacattgtga tctttggtat ggataaggat
    50941 caggtctatg accactatgc caagcatgat tattattcaa gaggcctata tgagagcgac
    51001 cctcagatta aagcagtagt cgacgctttt gtcaatggca ccattccaaa tagtcaacac
    51061 gaaggtatgg aaatctatga tgccctaatc acgcataatg atgaatactt cttgctagaa
    51121 gacttttctt cctatgtaaa agcacaggct aagattgatc ggctctaccg ccaaaaggat
    51181 agatggtcaa aaatgtcgct catcaacatt gcccattctg acaagtttac atcagatgat
    51241 accatcaccc agtatgccaa ggacatttgg cagctaaaac gctaatccat caaggaagaa
    51301 aaagcattag ttaccttaga ttgaagagag tgtcttttga gaccattttc ttcaatcttt
    51361 tttgattgca aaagaccttg ggaatcagat cagctgcctg cctaatactt tggcctatca
    51421 aggtattttg gaatttgtta atctttttgt tataatagtg gtgtgaagct attttttaaa
    51481 tgaaaaagcc aacacttcaa gatggtgtta aagtaaggtt agtattagtc taagaaagcg
    51541 taaccacatt aaagaaagct gttgacattc tcaattttaa ggaatagaat aacaaagtaa
    51601 aaaattttta aaaggagtat tctattatga atcctatttt cgcattggct cttgcctgct
    51661 ttggtgtatc acttgccgaa ggctttttga tggctaatct ctttaaatca gcgtcacgcc
    51721 aaccagaaat tatcggtcaa ttacgttcct tgatgatcct aggtgttgcc tttattgaag
    51781 gtaccttctt cgttaccctt gttatggcct tcattctaaa ataacagcct atttgatata
    51841 gaaaaggagg gtattaaatg gaagaagcta aagtaccgat ggtagagctt ggtccaataa
    51901 cctttaattt gaccctactt gctgtttgta ttgttactat cctactgata tttggctttg
    51961 ttttttgggc aagtcgtcag atgacattaa aaccaaaagg caagcaaact gcgttagaat
    52021 atttaatcag ctttgttaat ggtattgggg aagagcattt ggatagtcat cttcagaagt
    52081 cttattcgct tttacttttt accatttttc tttttgtggc agttgccaac aacttgggct
    52141 tatttacaaa gctagaaaca accagtggct acaacctatg gacatcgcca acagctaatt
    52201 tggcctttga cctagcccta tctctgtttg tgacgcttct tgttcatatc gaaggcatta
    52261 gacgtcgtgg ttttggcgct tatttaaaac gctttgcgac accttggcca atgactccga
    52321 tgaacctatt agaagaattt accaacttcc tatcacttgc tatcaggctg tttggtaata
    52381 tctttgcagg agaggttgtg acaggcttga ttgttcagct ggccaattat cgcctgtatt
    52441 ggtggccaat tgctttcctt gttaatatag catggacagc cttttccata tttatttcct
    52501 gcatacaagc ctttgtattt acaaaattaa cagcaacgta tttaggaaaa aaagttaatg
    52561 aatcagaaga ataagaaggg aggacaaacg aatgtcagtt acaattggtg agctcattgg
    52621 gaattttatt ctggtaacag gctctgtcat cgtcttgttg ctcttgatta aagcctttgc
    52681 ttggggtgct atcgaagctg ttttacaggc acgctcacag caaatttcac aggatattga
    52741 ccaagcagag caggcgcgtc tcaacgccca gcagcttgaa aaggaaggtc aagccaatct
    52801 agaagccagc agatcagagg ctagtcagat tgttgaggca gccaaagaaa ctggtaaagc
    52861 acaggagaca cgcattgtag cagaggctac agaagaggca gatcgcctaa aagcagcagc
    52921 gttgacagat atcgaacaca gcaagtcaga ggctatttca gccgttaaga cagaaatgtc
    52981 agatttgaca gttttactag cagaaaaaat tatgggagcc aatcttgata aggcggctca
    53041 aagccagctt attgatcgct atcttgatga tttaggagag gcttaatgac caaaaaagaa
    53101 caagctctta tcgagcaata tgcaaaaagt cttgtgcagg tctgtcagga gcgagacact
    53161 cttgaagcac tgcaggctga tgtgcttgcc attttagagg tttttaaagc tactaatctt
    53221 gctaagacat tgtcaagctt agcggttcca cgtgctaaaa ggcttgagct agtaaggcag
    53281 cttcaaggag ataatatcgt ttatctgaat aacttgctag aagttatgct gcaaaatgag
    53341 cgtgaagctt atttatatca agtgcttcta agggttttat ccgagctggc tagtgtctca
    53401 aatcaatatg acgtgacagt tacatcagca gttcctttaa gtgaggagca aaagcagcgt
    53461 gtgcgtacag tggtttcaaa gagacttgca gtaaagacag gtcgcttaat cgaaaaggta
    53521 gatccttctt taattggagg atttatgatt agcgtcaata ataaggtaat tgatacaagc
    53581 attcgtcgtc aattacaagc atttaaaatg aatttaaaat agaaagtggt gtgacttttg
    53641 gcaattaatg cacaagaaat tagcgcttta attaaaaagc aaattgagaa cttccagcca
    53701 aatttcgatg tcacagaaac tggagttgtt acctatattg gtgatgggat tgcacgtgct
    53761 cgtggcttag acaatgcgat gagtggcgag cttcttgaat tttcaaatgg taccttcggt
    53821 atggctcaaa acctagagtc aaacgatgtt ggtatcatta ttcttggtga tttttcaacg
    53881 attcgtgagg gtgatgaagt caaacgtacc ggtaaaatta tggaagtgcc agtcggtgaa
    53941 gctctcattg gacgtgtggt caatccactt ggtcagcctg ttgatggctt aggtgacatt
    54001 gagacaactg gctttaggcc tgttgaaact ccagctcctg gtgttatgca gcgtaagtct
    54061 gtttttgagt ccttacaaac cggtctaaag gctattgatg ctttggttcc gatcggtcgt
    54121 ggccagcgcg agctgattat cggtgaccgt cagacaggta agacgtctgt agccattgat
    54181 gccatcttga atcaaaaggg gcaggacatg atttgtatct atgtcgctat tggtcaaaag
    54241 gaatcaacag ttcggacaca ggttgaaacc ctacgtcgtt atggtgcttt ggattatacc
    54301 attgttgtaa cggcttctgc ttcacagcca tcacccttgc tgtttattgc accttatgct
    54361 ggtgttgcga tggcagaaga gtttatgtac aatggcaagc acgttttgat tgtttatgat
    54421 gacctgtcta agcaggcggt agcttatcgt gaattgtcgc tcttgcttcg tcgcccacca
    54481 ggtcgtgagg cctatccagg agatgttttc tacctgcata gccgcttgct tgagcgctca
    54541 gctaaggtgt ctgatgactt aggtggtggc tcaattacag ccttaccatt tattgagacg
    54601 caggctgggg atatctctgc ctacattgcg acaaacgtga tttcgattac agatggtcag
    54661 attttcttgc aagaggatct ctttaactca ggaatccgcc cagctattga tgctggctcg
    54721 tcagtatctc gtgtcggtgg ctctgcacag atcaaggcta tgaaaagggt tgcagggact
    54781 ttgcgtcttg acctagcctc ttatcgtgag ttagaagcct ttacacaatt tggctcagat
    54841 ctagatgcag caacgcaagc aaaattaaat cgtggtcgtc gtactgttga aatcctaaag
    54901 cagccactgc acaagccctt gcctgttgaa aagcaggtgg tcattttgta cgctttgacg
    54961 catggatttt tagatgatgt tcctgtagat gatattttag cctttgaaga agcactttat
    55021 gactactttg atgcgcatta tgatcactta tttgaaacaa tccgtacaac caaagacctt
    55081 ccgcaggagg ctgagctgga cgttgctatt caggccttca aagcacagtc aaactttaaa
    55141 taaaagaggg gggtactagt atggcaggct ctctaagtga aattaaggct aaaatcattt
    55201 caaccgaaaa aacaagcaaa atcactagcg ccatgcgtat ggtttcttct gcaaagcttg
    55261 ttaaatctga gcaagcagct cgtgattttc aaatctatgc ttcaaagatt cgtcagatta
    55321 caacagactt actgaaatca gacctgacaa caggctcaga taatcccatg ctggtgtctc
    55381 gtcctgtgaa aaagacaggc tatattgtta ttacctctga taaaggactg gtcggtggtt
    55441 acaattcaaa aatcttaaag tccattatgg acatgattca ggaataccat gccgctggcg
    55501 attatgagat tatctcaatt ggcagcatcg gctcagattt ttttaaggcc agaggtatga
    55561 atgttgcctt tgagctgcgc ggcctagcag atcagccaag ctttgatcag gtcggaagga
    55621 ttatctctca gtctgtaggt atgtttgtca atgagatttt tgatgagctg tacgtctgct
    55681 acaatcacca tgtcaatagc ttgacgagcc aggttcgggt tcagcgcatg ctgccgattt
    55741 ctgatttggt tgccgaggag gccgcagaag aaggtgtcac tggatttgaa ttagagccaa
    55801 accgtcatgt gattttggag cagctgctgc cgcaatttac tgaaagctta atttatggtg
    55861 cgattattga tgcaaaaaca gcagagcatg ctgctggcat gactgcaatg cagactgcca
    55921 ctgacaatgc caagcatgtg atcaatgatt tgaccatcca gtacaatcgt gcgcgtcagg
    55981 cggccattac acaagaaatt acagaaattg tagctggtgc taatgcactt gaataagctt
    56041 attgtatgct gatagcgctc tagcagagac ctattagcac ttaatgtcat cttcaaagct
    56101 agatgacatt tgggattaat gagctagggg ccttttaccc ttagctactc gaatttagaa
    56161 aaattcagct taatccccta ctatcgaata taaggagaaa aacatgagct caggcaaaat
    56221 tgctcaggtt gttggtccag ttgtagacgt tgtgtttgcg agtggggaca aactaccaga
    56281 gattaataat gcgttgatag tttataaaga tggcgataaa aagcaaaaaa tcgttctcga
    56341 ggttgcccta gagcttggag acggtatggt acgtacaatt gctatggaat caaccgatgg
    56401 gcttacacgt ggattagagg ttcttgatac tggtcgtgcc attagtgtac cagttggtaa
    56461 agagactcta ggtcgtgttt tcaacgttct tggtgaaacc atcgacctag aagcaccatt
    56521 tgcagatgat gttaatcgtg aaccgatcca taaaaaagca ccagcctttg atgaattgtc
    56581 aacatcatca gaaattcttg aaacaggtat caaggttatt gacctgcttg ccccttactt
    56641 aaagggtggt aaggtcggtc ttttcggtgg tgccggagtt ggtaaaaccg ttcttatcca
    56701 agaattaatc cacaatatcg ctcaagagca tggtgggatc tcggtattta ccggtgttgg
    56761 tgagcgtacg cgtgaaggaa atgaccttta ctgggaaatg aaggaatcag gcgttattga
    56821 aaaaacagcc atggtttttg gtcagatgaa tgaaccacca ggagcccgta tgcgtgttgc
    56881 cttgaccggc ttgacaattg ctgaatattt ccgcgatgtt gaaggccaag acgtcctgct
    56941 cttcattgac aatattttcc gctttactca agcaggctca gaggtatcag cccttctagg
    57001 tcgtatgcct tcagccgttg gttaccagcc aacacttgcc actgaaatgg gacaattgca
    57061 agagcgtatc acctcaacga aaaaaggctc tgttacctct atccaagcca tctacgtgcc
    57121 agctgatgac tacactgatc cggcgccggc aacagcattt gctcacttgg attctacaac
    57181 taaccttgag cgtaagctga cgcagatggg gatttaccca gcggttgatc cactggcttc
    57241 aagttcacgc gcgctgtcac cagaaattgt tggtgaggag cactatgcag tagccacaga
    57301 ggttcagcgt gtcttgcagc gctatcgtga attgcaggat atcattgcta tcttaggtat
    57361 ggacgagctg tcagaagagg aaaagacatt ggtaggacgt gcgcgtcgga ttcagttctt
    57421 cttatcgcaa aactttaacg tcgcagaaca gtttacaggc cttcctggct cttatgttcc
    57481 agttgccgaa accgttcgtg gcttcaagga aatcctagaa ggaaagcatg accaccttcc
    57541 agaagacgcc tttcgtgctg ttggaccaat tgaggacgtg atcgaaaaag ctaagaaaat
    57601 gggcttttag tgaggtgatg ccatgacaca aatgactgtt caggtggtta cgccagatgg
    57661 gatcaaatat gatcatcatg ctaagttcat ctcagtaacg acaccagatg gtgagatggg
    57721 gatcttacct aaccacatca atgtgattgc tcctttacag gtgcatgaaa tgaagattcg
    57781 tcgtgtcagt gaagacgatc gcgttgattg ggttgctatc aatggtggga tcattgagat
    57841 caaagacaac gtggttacca ttgttgcaga ttcagccgaa cgtgatcgtg atattgatgt
    57901 tagccgagca gagcgggcaa aattgcgagc agagcgtgac attgcagagg ctgaaaccac
    57961 tcatgatatt gatgaggtgc ggcgtgctaa ggttgctttg cgacgtgcct tgaaccgcat
    58021 caatgttagt aaaaaatagt aaaatgagtc taacctacca atttaaccaa gacagagcga
    58081 gtagcgctgc ttaggaaagg gtgtagatag actcttttat ctttttatag aaaaaatacc
    58141 ctcttt
//
LOCUS       DARYLJ010000007        53512 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYLJ010000007 DARYLJ010000000
VERSION     DARYLJ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53512
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            3..2189
                     /locus_tag="TU746_000372"
     CDS             3..2189
                     /locus_tag="TU746_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL0890755.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
     gene            complement(2301..3020)
                     /locus_tag="TU746_000373"
     CDS             complement(2301..3020)
                     /locus_tag="TU746_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0890756.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
     gene            complement(3626..3985)
                     /gene="rplT"
                     /locus_tag="TU746_000374"
     CDS             complement(3626..3985)
                     /gene="rplT"
                     /locus_tag="TU746_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL0890757.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(4046..4243)
                     /gene="rpmI"
                     /locus_tag="TU746_000375"
     CDS             complement(4046..4243)
                     /gene="rpmI"
                     /locus_tag="TU746_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL0890758.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(4283..4813)
                     /gene="infC"
                     /locus_tag="TU746_000376"
     CDS             complement(4283..4813)
                     /gene="infC"
                     /locus_tag="TU746_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL0890759.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(4828..4950)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4974..5654)
                     /locus_tag="TU746_000377"
     CDS             complement(4974..5654)
                     /locus_tag="TU746_000377"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL0890760.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(5669..6166)
                     /locus_tag="TU746_000378"
     CDS             complement(5669..6166)
                     /locus_tag="TU746_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL0890761.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            6215..6412
                     /locus_tag="TU746_000379"
     CDS             6215..6412
                     /locus_tag="TU746_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL0890762.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(6399..6887)
                     /locus_tag="TU746_000380"
     CDS             complement(6399..6887)
                     /locus_tag="TU746_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL0890763.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(6932..8155)
                     /gene="pepT"
                     /locus_tag="TU746_000381"
     CDS             complement(6932..8155)
                     /gene="pepT"
                     /locus_tag="TU746_000381"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL0890764.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(8325..9344)
                     /gene="galE"
                     /locus_tag="TU746_000382"
     CDS             complement(8325..9344)
                     /gene="galE"
                     /locus_tag="TU746_000382"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL0890765.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(9412..11781)
                     /locus_tag="TU746_000383"
     CDS             complement(9412..11781)
                     /locus_tag="TU746_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL0890766.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(11861..13024)
                     /locus_tag="TU746_000384"
     CDS             complement(11861..13024)
                     /locus_tag="TU746_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL0890767.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(13038..14522)
                     /locus_tag="TU746_000385"
     CDS             complement(13038..14522)
                     /locus_tag="TU746_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL0890768.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(14526..15767)
                     /locus_tag="TU746_000386"
     CDS             complement(14526..15767)
                     /locus_tag="TU746_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL0890769.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDEKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(15751..16107)
                     /locus_tag="TU746_000387"
     CDS             complement(15751..16107)
                     /locus_tag="TU746_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL0890770.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(16112..16801)
                     /locus_tag="TU746_000388"
     CDS             complement(16112..16801)
                     /locus_tag="TU746_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0890771.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(16831..18576)
                     /locus_tag="TU746_000389"
     CDS             complement(16831..18576)
                     /locus_tag="TU746_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL0890772.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(18573..19580)
                     /locus_tag="TU746_000390"
     CDS             complement(18573..19580)
                     /locus_tag="TU746_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0890773.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(19601..20809)
                     /locus_tag="TU746_000391"
     CDS             complement(19601..20809)
                     /locus_tag="TU746_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890774.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(20809..21612)
                     /locus_tag="TU746_000392"
     CDS             complement(20809..21612)
                     /locus_tag="TU746_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890775.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(21612..22547)
                     /locus_tag="TU746_000393"
     CDS             complement(21612..22547)
                     /locus_tag="TU746_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0890776.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(22537..23691)
                     /locus_tag="TU746_000394"
     CDS             complement(22537..23691)
                     /locus_tag="TU746_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL0890777.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(23816..24664)
                     /gene="rfbD"
                     /locus_tag="TU746_000395"
     CDS             complement(23816..24664)
                     /gene="rfbD"
                     /locus_tag="TU746_000395"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL0890778.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(24806..25144)
                     /locus_tag="TU746_000396"
     CDS             complement(24806..25144)
                     /locus_tag="TU746_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL0890779.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(25442..26551)
                     /gene="rpoD"
                     /locus_tag="TU746_000397"
     CDS             complement(25442..26551)
                     /gene="rpoD"
                     /locus_tag="TU746_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL0890780.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(26560..28374)
                     /gene="dnaG"
                     /locus_tag="TU746_000398"
     CDS             complement(26560..28374)
                     /gene="dnaG"
                     /locus_tag="TU746_000398"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL0890781.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            28621..28995
                     /gene="mscL"
                     /locus_tag="TU746_000399"
     CDS             28621..28995
                     /gene="mscL"
                     /locus_tag="TU746_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL0890782.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(29221..29397)
                     /locus_tag="TU746_000400"
     CDS             complement(29221..29397)
                     /locus_tag="TU746_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL0890783.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(29552..30364)
                     /locus_tag="TU746_000401"
     CDS             complement(29552..30364)
                     /locus_tag="TU746_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0890784.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(30432..31547)
                     /locus_tag="TU746_000402"
     CDS             complement(30432..31547)
                     /locus_tag="TU746_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL0890785.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(31817..35458)
                     /gene="addA"
                     /locus_tag="TU746_000403"
     CDS             complement(31817..35458)
                     /gene="addA"
                     /locus_tag="TU746_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL0890786.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(35448..38669)
                     /gene="rexB"
                     /locus_tag="TU746_000404"
     CDS             complement(35448..38669)
                     /gene="rexB"
                     /locus_tag="TU746_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL0890787.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(38878..40278)
                     /locus_tag="TU746_000405"
     CDS             complement(38878..40278)
                     /locus_tag="TU746_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0890788.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(40420..42561)
                     /locus_tag="TU746_000406"
     CDS             complement(40420..42561)
                     /locus_tag="TU746_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890789.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(42568..44001)
                     /locus_tag="TU746_000407"
     CDS             complement(42568..44001)
                     /locus_tag="TU746_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL0890790.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(44007..44684)
                     /locus_tag="TU746_000408"
     CDS             complement(44007..44684)
                     /locus_tag="TU746_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL0890791.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(44698..45393)
                     /locus_tag="TU746_000409"
     CDS             complement(44698..45393)
                     /locus_tag="TU746_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL0890792.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(45521..46156)
                     /locus_tag="TU746_000410"
     CDS             complement(45521..46156)
                     /locus_tag="TU746_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL0890793.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(46146..46685)
                     /locus_tag="TU746_000411"
     CDS             complement(46146..46685)
                     /locus_tag="TU746_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL0890794.1"
                     /translation="MVKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(46974..50690)
                     /locus_tag="TU746_000412"
     CDS             complement(46974..50690)
                     /locus_tag="TU746_000412"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL0890795.1"
                     /translation="MMKRLGENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            51170..51715
                     /locus_tag="TU746_000413"
                     /pseudo
     CDS             51170..51715
                     /locus_tag="TU746_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            51796..52251
                     /locus_tag="TU746_000414"
     CDS             51796..52251
                     /locus_tag="TU746_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890796.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            52251..52538
                     /locus_tag="TU746_000415"
     CDS             52251..52538
                     /locus_tag="TU746_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890797.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            52531..53079
                     /locus_tag="TU746_000416"
     CDS             52531..53079
                     /locus_tag="TU746_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL0890798.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(53258..>53512)
                     /locus_tag="TU746_000417"
     CDS             complement(53258..>53512)
                     /locus_tag="TU746_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0890799.1"
                     /translation="EPKPEPEAKPKPMPKPETKPEVKPEAKPMPKPEAQKGDKPAVPK
                     AMEHKLPSTGEATAPFFTAAALAVLASLGVAVVSRKRKKH"
BASE COUNT        15870 a        12213 c        10133 g        15296 t
ORIGIN      
        1 ctgtgaagaa ttttaaaaca tttatcacaa gctttatcaa tacaagatta ggctttgtgc
       61 taacgcttct cttctgcttt tggataaaaa ccctatgggc ttaccatgct gacttttcac
      121 tagatttggg aaatgcctat caggtctttc taacaattat taacccaatc cctctagctt
      181 tgttactatt gggatttacc ctttatatca agaatactag ggccttttat atcagctctt
      241 ggatcgtcta tattatcctt aacctcttgt taatatcaaa ttctatttat taccgagagt
      301 tttcagattt cattacggtt agtgctatgc tagccagtag taaggtttct gctggtttag
      361 gagactctgc tttaaacctt ttgcgcattt gggatattgt ttacgtcctt gatttcatca
      421 ttctgattag tttatcagta actaagacca tcaaaaaaga cccgcgtcct tttaacaagc
      481 gggcttcctt tgctgttaca gcactgtctt gcttgctctt atctgttaat ctgtttcttg
      541 cagagattga ccgcccggag cttctgacta gaggattttc aaatacctat atcgttagag
      601 cgcttggatt gcctgctttt accatttaca gcggaaacca gacctatcaa gcacaaaaag
      661 agcgtaacgg agcaaccgct gaagaattag tcgatgttaa gcaatatgtc aagaaccact
      721 acgccgcacc tgatcctcaa tattttggaa tcggtaaggg aaaaaatgtc attgtgatcc
      781 acttggaaag cttccaacaa tttcttattg attacaagct caaggatgac gacaaggact
      841 atgaggtcac accttttatt aattccctct accactccaa tgccacacta gccttctcta
      901 actttttcca tcaggtcaag gctggaaaaa cgtctgatgc agagaccatg atggaaaatt
      961 cattatttgg cttaaacagt ggttctttta tggtaaatta tggcggcgaa aacacacaat
     1021 tcgccacacc atcaatccta gcacaaaatg gcggctatac tagtgccgtc tttcatggga
     1081 atgtaggaac cttctggaat cgcaataatg cttataagca atggggctat cattactttt
     1141 ttgattcaag ctatttttca aaacagactg ataaaaactc tttccagtat ggcctaaatg
     1201 acaaatacat gtttagagat tctatcaagt accttgaaca gcttcaacaa cccttctaca
     1261 ctaagtttat taccgtcagc aaccactacc cttacaccag ccttagaggc gaaagcagtg
     1321 aagagggctt tccactagcc aaaaccgatg atgaaaccat caatggttac tttgctacag
     1381 ctaactatct ggattcagcc ttgaaatcat tttttgatta tctcaaggcg acaggacttt
     1441 atgacaattc tatctttgtt ctatatggtg accactatgg tatttctaat tccagaaatg
     1501 tcagcttggc agaattacta ggtaaagacc ctgaaacttg gtccgaatat gacaatgcaa
     1561 tgctccagcg tgtaccatat atgatccata ttccaggcta taccaatggc gggatcaaag
     1621 aaacctttgg cggagaaatt gattccttac caaccttact gcatatcttg ggcattgata
     1681 ccagcaagat ggttcaacta ggacaggatc tcttgtcgcc acaaaatagt caaatggtag
     1741 cacaaagaac ctctggaact tatatcacgc cagactacac tagctatagc ggtcgccttt
     1801 acaacactca aacaggcttg gaaattacaa accctgatga gatgacaatg gctaaggtca
     1861 aagaaatacg agcagccgtt gctcagcagc tagcagctag tgacgctatc caaacaggag
     1921 acctactacg ctttgatacc gataatggtc tgaaacctgt tgacccaaca accttcattt
     1981 ataccaagca gctaaaacaa ctcaaagaga tatcagagaa attaggatca cattcaacca
     2041 gcatttatag taaaaatggc aacaaatcaa ctcaaaagct ctttaaagca ccttcttatc
     2101 tggagttaaa tcctaaagaa gccgaaaaac ctgaatctac ttcgtcttct gaccctaaag
     2161 aagaatccgt taaggaacaa agtcagtagt ggatgtctaa agcaagcctc actaggatcg
     2221 ctctcgtaga agactaaaag caagctaaaa gccttcattg agcgttacaa cttaatgagg
     2281 gctttttagt tctgacactt ttattgagga atggcctcaa agtattctgg atctggtgtc
     2341 ggttcaggtg ttggcacagg atctagctta ggctcaggct tcggttctgg tgttggcaca
     2401 ggatctggct taggttcggg tgtcggtgct gggctatttt cttgcgtcac aatataaccc
     2461 acataacagt aatcatcaac cttttcttct ggagtgtaag taaagcttac ccccttaacc
     2521 gtagtcttag tgacgatatc attgagatga cgtaccacat caactgcact aacagctgtt
     2581 gtcgcaccac cagctaccaa caaggcaatc aacacatagc taccgctttt cctatttttg
     2641 taaataagat agcctgaaac acttagtaag cctagcccta ctgccaaacc aaccagacca
     2701 tctgctgcac cacccgtttt aggcaagacc ttagcgttag ccttaggggt agacatcatt
     2761 ccttttggag atgctgtcac tccacagctt ttgtcgtaaa caagaacgta atgcaattta
     2821 tcttggatag gtacttcatt tggagtgcct ttttgaatgc ctgctttttg ttcatttgtc
     2881 agattagaat aggctgtata ggtcaaatct accgttaccg tatcagcatt agtgttggca
     2941 ttgacattag ctgctagcaa agatagacct aacatcgttg tagctcccat gtattgaaac
     3001 gctttagaaa aacgtggcat tataactatt ctccttaatg ttttgtagaa taaaaccaat
     3061 aactaaaaag gcatctccta tcatatcaat cttatgatta ttataggtaa atgtgatttt
     3121 tgtaagcact atctaaaaat ttcaaataca ctcatatcaa tagatattga ccaaatctca
     3181 gcagctttaa gcatatcata acaataaatc accttattga cacaaataga aaggacacat
     3241 ttatacttat cattttcatt ctattatatt aaaccatatc ttgtgttaaa atacaatgaa
     3301 attatgacat tatggctcct aaataagttg ttttgcattt tattattttg gtgatggatt
     3361 tgattaaaac tagaaatcat atatctcctt atatgatcat cacttgatgg actgctcaac
     3421 tgtctgatac aagattaagc cctttcttct tagttaacag ctaccaaaga aaggtaaatt
     3481 ggctccttta tactaaatta gagatagcta aaaacatctc aaatactctt gacaaaacgt
     3541 catgactgtc ttatctagct agattagcta acataaggca ttaaaaatag acttagaagg
     3601 tttctaagtc tacagtcgat ctctattatt tgccaagctt tgccttagca gcatcagcaa
     3661 gggctgtaaa agctgctgca tcattcaccg ctaaatcagc aagcatttta cggttaactt
     3721 cgatttcagc aagctttagg ccatgcatca attgtgaata tgacaagcca ttcatacgag
     3781 cagctgcatt gatacgtgtg atccatagct tacggaagtc acgttttttc tgacgacggt
     3841 cacgataagc atagtaataa gaattcatga cctgctcttt tgcagtacgg aacaagatat
     3901 gttttgctcc ataataacct ttagctaatt tcaaaatacg tttacgacgt ttgcgtgata
     3961 caacgccacc tttaacacgt gccattaata ttctccttca aataactctt ataattctag
     4021 taaatacctg ttacaaccct taatcttaaa ggccagtaac cattgcttta atacgcttga
     4081 aatctcctgc atgcaccata cctgctttac gaagatgacg gcgttgcttt ttagtctttc
     4141 catggaaacg gtgtgatgta aaggcacgga agcgtttcaa accgcctgaa cctgtacgtt
     4201 taaaacgttt agctgatgcg cggtgtgttt tttgttttgg cattttaata ttctcctctt
     4261 aacatatagt gtaatatgac aattacttct tgtctgaaat tggtgcaagc tgcataaaca
     4321 tttggcgacc atccattttt gctctttgct caataatagc aatatcttga gttgcctcag
     4381 caaaatcagc cagtacctta gcaccaatct ccttgtgagt aatcatacgt cctttaaaac
     4441 ggatagaaac cttaacctta tttccctttt caaggaactt acgaccatta cgaagctttg
     4501 tttcaaagtc acccttgtcg ataactgggc taagacgtac ttcctttaca gttacaacgc
     4561 tttgcttttt gcgttgctcc ttttgctttt tttgatactc aaatttgaac tttccatagt
     4621 ccataagctt ggcaacagga ggaacagctt gcggctggat taaaaccaaa tctacatttg
     4681 cagcatcagc taaagactga gcttcagata atggtttaat gcctaattgt tcaccttcaa
     4741 gaccaacgag acgaacttcg cgaacacgaa tctcatcatt aatgaataga tcttttttag
     4801 ctatgatctt cacctcttta tttttttaga gaaaaacgaa agcggactta atgaaccaag
     4861 cccgcacaca taatatcccg taggaatttg acatgtaggg ccagacaacc taggtcgcaa
     4921 ggcgagaagc tctcacttct gcttttctca ttattgacat tctaacaaat aaatcatgcc
     4981 atgtcaatta ttttttctgc tttttcctga ataaattgga caacagctga aatcgtgata
     5041 ccggtagtat caaagataat cgcgtcatct gccgccttta gcggcgaaac ttgacgatga
     5101 ctgtccttat aatcgcgtgc cgcaatctca gcctttaagg tgtcaaaatc agctgcaatc
     5161 cctttttcaa tattttcctg ataacgacgc tgcgctcttt cttcaacaga agcaatcaaa
     5221 aagatcttca actcggcatc aggcagcaca accgttccga tatcacgacc gtccatgata
     5281 atagcaccag tcctagcaat tcgtcgctgc tgattcacca gctcctctct aatctctggc
     5341 aaggcggaca cccaagaaac attattggtg acatcatttt gcctgatcgc cattgtcaca
     5401 tcttggtctc caagaaaaac cagttgtgag ccatcagctg cttttttaaa agaaattgga
     5461 cgctttgcca attcttgcag gattagattg acatcttctt tgtgataacc attttttaat
     5521 gcgatataag tcgctgagcg atacatggca ccagtatcta aataggtgta gccaagattt
     5581 ttggcaataa tcttggctac cgtacttttc ccacttgagg ctggtccatc aatcgcaatt
     5641 ctaattgctt tcatcttttc ctctttaatt atttgatatt gacctcgtca cctggattgg
     5701 cataccagta gccttgggtc atatgatctg ggtttagggc ctgtaattgc tcaacagaaa
     5761 ttccagcacg agctgcaata gatgttgctc cttctcctgc taatactgta attgtctttc
     5821 ctgctgcctc tgtagaaggt gctgtttcag tcttagaagg acttgttgtg tcactagctg
     5881 ctgagctatt agagctcgct tttggctttg tttttggttt tgagctgacc ttctttgttg
     5941 tctttttctg agttgatgcc ccgtaaaatc ctgttgtctc attttgcttg ttactaccgc
     6001 tgtttgacgt atagaagaaa ataaaaagta tggcaacaat aatgacaaag aaaacactta
     6061 acaaggcagt caaccaaggt gtgctaatga gtgctcctct tgattttctt gttcttgtcg
     6121 ccttattgtc atcaacaatt ttttcttccc atggttcttt agccatgatt cttccccctt
     6181 gttaatttaa caaaatcata ttagaataat acctatgaaa gtatctatcc ttccagaaaa
     6241 atgcattgcc tgtggtcttt gccagaccta ctctgctctt tttgactatc atgatgatgg
     6301 tatcgtcaaa ttggctcagt ctgatgagtc aagtcaactc atagatccta atgatcatga
     6361 tgccatctta gcagtaaaat cctgccctac taaagccctt accctcgagt aagaggcttt
     6421 ttttcgtatt ggtaggcttc aaaataatcc agtttaatga agttatctag taatataacc
     6481 tctcccttaa aataaggatt aatcgctaga tcatctaaaa aatatttttt aggccatttt
     6541 ctcatgtaaa aaaggtagct cttatcacca acaaatagac aaaccgttga tttagtaacc
     6601 tcaattttgg taattgaggc aatcatcagt ctgtgcggag caaatagctt taaagatacg
     6661 atcttcaaga caccattatt ctcaattaca aaataacgat gcaggccaag tcccactaat
     6721 atagcaaata aagcaaacaa gacaaaaaca cgactcggta tttctgttct ttcatacaat
     6781 aaggacaggc caataaaaat aggcgcaaca gcaattgacc aataaataat agaccaagac
     6841 agctctggct gccaatgata ccttacttta ccgaataatt taatcatgct tttccatcac
     6901 ctccaatccg ttctgagcat tttgggtgat gttaagcctt ttggacaatg ccaagaatca
     6961 catcaactgc cttttccatc gtttgcagac tcacaaattc aaacctgcca tgcatatttt
     7021 caccacctgc aaaaatattt ggcgttggaa tccccataaa ggaaatcttt gagccatcag
     7081 taccaccacg aatcggctcg ataactggct taatagctag gtcctccata acagccttag
     7141 ctagattcac aggtgtcatg tccttttcaa tcaccttttt catgttatag tactgatccg
     7201 tcactgttac aaatacacgc tctgctccaa gctgactatt catctcctca gctagctgtg
     7261 ttacaaaggc ctttctagct tcaaaggagc tatcctcaaa atcacgaata atataagagg
     7321 cctgtgcttc ttctacagta ccagacatgc tgtgtaggtg gtaaaagcct tgatagccgt
     7381 ccgttttttc aggacgatcg tcaactggta attgactatg gaaatccatt gctagctgca
     7441 gggcattaat catctgattt ttagctgtac cagggtgaac attgcgacct aacaccttga
     7501 gctctagggc tgctgcgcta aaggtttcat attgtagctc gccaagcgga cctccatcaa
     7561 tagtataggc aaagtcaaca tcaaaagcat taacatcaaa cttatctgca ccaacaccaa
     7621 tttcttcatc aggtccaaag gcaaccttaa tgtcgcaatg ctcaatctga gggttggcaa
     7681 caagaaactc aatagccgtc atgatttctg caattccaga tttatcgtca gctcctaaaa
     7741 gggttgtgcc atcagttgta atcagggtct gtcccaaata ttggttgaga tttggaaaat
     7801 cctctgggca taaagaatag cctgactgac caagcttaat ctccccaccc tggtagctct
     7861 caataatctg aggggctact ccttctgcat taaaatcagc agtatccata tgcgcaataa
     7921 aaccaatttt ccgagtcaat ttgctgctgt tagctggtaa gcttccaatg aggtagccat
     7981 tagctggatt gtaatgaatg tcctgtaggc caatagcttc catctctggc tttagcactg
     8041 ttagagcaaa gtcagcttga ctcttggtgc ttggagttgt agtgcttgct ggattgctcc
     8101 ttgtgttgat ttttacatag ttcagaaatc gttctaataa agtttcgtat gtcatagatc
     8161 acctcgataa gttttcgtta ctattatagc ataaaaggac ctaaaatact tgcctaagct
     8221 cagtttttta cagtgcttta tctgttctgt tacagttgcg ttctcataaa aagacagctg
     8281 ccaagaaagc tcttgacagc cttgattatt catcagccca tgccttaatc ctcataacca
     8341 tttgggtgct tgctttgcca tctccaagta tctgtacaca tcctttctaa gccgtactct
     8401 gcagtccagt taagctcttt tttagccttg ctagcatcag catagcaggc tgcgatgtct
     8461 ccttgacgcc ttggtaatat cttgtaagga atagacctgc caaccacctg agaaaaggct
     8521 tcgataatat ctagcacaga atagcctgta cctgttccta aattataaat agataggctt
     8581 ggctcttcag caaactttgc aagcgcagcg acgtgtcctt tagccagatc aacaacatgg
     8641 atataatctc taacgccagt gccgtccttg gtctcataat catcaccaaa aacgccaaca
     8701 caatccagct taccaacagc tacctgagaa acataaggta ataggttgtt aggtatgccc
     8761 ttaggatcct ctcctaaatc accagactca tgagctccga taggattaaa ataccttaac
     8821 aatacaatat gccactcatt atctgatgca tagaggtcct tgaaaatctc ctctagcatc
     8881 agctttgtcc taccgtaagg attggtcact gatagtggaa aggtttctaa aataggaacg
     8941 gtatgcggat ctccataaac cgttgctgag gagctaaaaa tgatcttttt acaattaaag
     9001 gctgtcatta cctttagtag ggtcaatgtg ccagagatat tattgtcgta gtaatcaagt
     9061 ggaatcctgc ttgactctcc aacagctttt agccctgcaa agtgaatgac actcacaata
     9121 ggatgcttac tgaaaatatc tgttagcagc tgttgatcgc gaatatctcc ctgataaaag
     9181 gtcacttctc ttccagctat cgaggcaaca gcagctaggc ttttaggatt tgaattgcac
     9241 aaattatcaa ccacaacaac gtcatagcca gcagctagca gttcaacaca ggtgtgtgac
     9301 ccgatatagc ctgcaccacc agtaactaaa atacttccta acattgatta tatacctgac
     9361 tttctaataa ttactaatat tataactgat tactcccaaa aagtatatct atcatttcat
     9421 tttaaagaaa tcaggatagg cattaatgta gcccttgcct tcaataagat catattctaa
     9481 cagctttaag tcagaggcca cctgcttttg agcagcagtt agctggctgt catcgctatt
     9541 tctggtatcc aagacatctg tcaaaagagc gtagtaagga gacaccttgg aatccgtatg
     9601 ctctagcaat aaagaggtaa aatcactgga attaacacga ggtctagcca atttgttggt
     9661 ctgatgattg ctccagatga aataatctgt taaatatttg acctcctcat cattcttaaa
     9721 gacctgatct ggataaaagc caggtaaatg atcaccataa aacacaactg taataggctt
     9781 gtcaaccttt tccagtgctg ataaaaaggc ctttgttgac ttgtcggtaa tgcttaataa
     9841 attcacataa ctttgcaggc tatccgtctc agactggtcc agtcctgcta ggctaacatc
     9901 aacatctctt agctctgtgt accaagggcc atgattttgc atggtaatca ctgaaaagaa
     9961 ttgacttctt ttggggttaa gctggtctaa aatattgtca taggttgact catcactata
    10021 gcttgagctc attcgtatca agtgctttgg cttgtcagct gaatcctctg tggcaatgaa
    10081 ggtatcaaat cccaatttgt tgtaaacgat ttttcgagag taattgttgg cgctcgcaag
    10141 gtgcaaaaca atcctatcct taggcgaaaa ggcattacta atggcaggcg aaaacttcaa
    10201 cttaggaaag acatcagaat acaaaatcga aactgttgga ttgaggttat attttggtag
    10261 gccaaatagg ctttgaaact ccatattagc tgtaccgccg ccatagccat cagaggtcat
    10321 taggccactc gttgtggttt ccatgatatg atggatctct gcaataggat ccttggccaa
    10381 ttgaacccca gaaatcctag ctgggtcagc aaagctctca ctcagtatat aaatcactgt
    10441 ttgatcagaa atacgctgat gcctttgctt attgatatca gcagctctag cttgatattt
    10501 ctgataaatc ttttgcatag cgctcttgct atagcctgaa ggctgattaa tggtgctggt
    10561 ggtaacctgc ttgaaccaaa caaagctcaa ggattgaaac cttgcattgg ttgtaagacc
    10621 ataccagtca atatcaaaga cattgtagac tgatgacaga actggaatac cttttttgat
    10681 ttcaccatct ttattttggc taaatacaaa aaggatagag gcaaatacca aaaggataga
    10741 gcctattgac atcagtctaa gataaagcgc tgataggatc ttttctctaa agtatctttt
    10801 atacaaaaca tagatcagca gacccgacaa gactagtatc aaaataatac taatgatttg
    10861 agtcagacta atgtaattca agaaaaactt aatctctttg atccatttca aatctgaaaa
    10921 caataaaggc tcacttcgct gcttgtattt ttcaatatta acaatactga ttaaagctcc
    10981 gatcaccgta ttgacaaata aagcaatgat atagttgtta atgagcaaaa acaccagcac
    11041 aaaaaagagg gtcaagacaa gcacctgaaa cagggttgca cctggaataa tcactgcccc
    11101 atgaaaatca ccatatgctg tgatcccagc ctgaataaag taattaaaga tgatccctaa
    11161 aaataagctg gtcactagag ctaatctaag accccatcgc ttgctcaaaa cctcgataaa
    11221 ggctgtgacg atgaggtaat aaaccacaaa cgtcagcata taagagcaaa agctatactt
    11281 aaagagattc aggctaacaa ggtttgactg actatctaaa ggccaataat cattttgctt
    11341 aatcacagtc ttaaataaag agctgttcag cgttaagact gaaaaagcct gactaagtaa
    11401 aatgacttgg attcctctgt ttgattggta gtccttctta aacaggtatt tttttaagag
    11461 aacccctaaa ataagcaggc tgactaaagc tgccagactg agtagcattt cctgaatcgt
    11521 acgattactg atggtaaacc tgctgttgtt tttattgatg gctaaggtga tatagctatt
    11581 agcaacagca tagtagctac tgacagctac agaaacaata agcagctttg aggaagcatg
    11641 cttgatcagc aaacatgcca ttccagctat taacactaag acaagccacg aaccataagc
    11701 tcccttattt aacgtgtttt tgcttaccgc aaaaatagat aaataaagag atgaaaggct
    11761 aaacaatatc atatcaagca tttctagatc aactaactgg cgagcttttg aaattatctt
    11821 cgttattata atggtcacac cctttcctaa ctgctaaaag ctagacatta ctctctgact
    11881 cagaagcgat tacctctgtt actaattgac gaacagtgac ctcccaggta aagcctgaaa
    11941 gcacctgctg atgaatggct tcttgcaggt cacaccgttt ttctttgtgc tcaatcaaat
    12001 gatccaactg ccttttaata tcagagactg tatcatcaat gatgattccc tgtgacgggc
    12061 tcgttatcac ttccttgaca ccacctctat ctgttgctaa tacagcacat ttcaacatac
    12121 ctgcctctaa tacagctgtc ggaagccctt cagcatagat ggacggatta acaaaaatat
    12181 cagattgaga cagcaaagac atggtctcag caaaattcag cttgcctgta aagatgatgg
    12241 actgatcctc tttatagcta tctcttagtg aagcaagcaa gggaccatct ccagcaacca
    12301 ccaagacagc cctgtcctta tatgtcagct gctcaaaagc ctccagcagc aaaagaatcc
    12361 ccttttcctt gatcactcga cctgcaaagg taataatgac cttatcctgc aaagctggta
    12421 aataagcctt tgacttaaag acctcataaa gatcagaatc aactgaattg tagatgacgc
    12481 ctttggcttt tattccaaag gtcttgagcc atgccatact gcgcttagac accgcataaa
    12541 agtcgggctg ataggctttg acaaaaaagg taattacatg ctcatagact ttagcaaaca
    12601 agtctagtag ctggtgacct ttaacatttt cgcccacctg aacatagcca ccaccatgct
    12661 cgatcacaat actagggatg gcttttcttt tggctagctt caagcccatg aggcttgtca
    12721 aataaaatcg tgtattgcag atcacaaagt caatacgttc ttccatcagc tccgccagca
    12781 tgctatgata cagatcattc ttatctaaaa tcggatagcg ctgcttaaat agctgctttg
    12841 aaggaaatcg gtaataagta atggcttgat ctctttcaat agggctcagc tggtggctgt
    12901 tgctggttac aatgatgata cggtagccta ggctcactaa ttgttgcgct attttttctg
    12961 tataccgctc tactcctcct agatgagggc ttgtaaagcc gctaaaaatg gctattgttt
    13021 tcaaagcttt tcccttctta tgtataatat tgcagcattg ttcgagtaat catacctagg
    13081 atcaatagca acgagccaat aagaacctgt ttattactta ataggccttg ggccttttca
    13141 aggtatttgt tattagaggc cagcaagacc aacactaaag ggatcacacc caaaaagtac
    13201 ctatcttgaa cccctagcac attaaggtct ccaactggcg taaaggtcaa ataaaggcta
    13261 aaggtaatac cgcctattat tcctaaagac atcaatccca taccaaagcg agataaggtc
    13321 ggcagctgaa gcttgttggc attagtgatg acaacagcaa aataataaac catactaatt
    13381 ggcatgagct ctaccatacc gtatgataaa gggccaaaca tgtaaatccc tgaaggatta
    13441 aggatatgag ccaacgtgtg tcttagcagc ataaagccat atactatagg gttccttaac
    13501 acagtcagta gctgctcttt agcattgacc ttctggagaa agtcagccat atccacctga
    13561 ggtgacttga tttgaccata tacctttaac caaaaaacag tcacaaccag caccgtcaga
    13621 attgacaaca gctttagcag aaacgtgcga gaggcttttg ctccaaattg acgtgaaggg
    13681 ataaaaagca gcaacaaaat caataaaata taaggcagct tagtaaaggt aatgattgag
    13741 cacagcaggg tataccaaaa gagcttggat aagggaatct tttcagttgt agccatctga
    13801 acaaataaag aaatcgtcag aataatcaat ccaatagaga cacaatcctg attataagaa
    13861 ccagcaagat agatattcat cggaaggaga cttcctacag caagcagctg cttgcctgct
    13921 gtcagcaatc gtaaggcaac aaaaaccaag atggcatagg caagaacatt acaaagccta
    13981 cctaaaaggt aagataagcc catggtcaag cctaagctcc ttccaataaa taagcctatt
    14041 acctgtggta tgtaggcaaa gttataatag ccatttgttg agcgaatttc cttaaatgaa
    14101 atagcctcat ctgtatggtc tctgctccac agctgaaagc gtaagggctt gccattgttg
    14161 tggtccataa gattaatgtc atcagtcacc agcagctttg agtcatcatt ggttaaatta
    14221 agatttccct cagataagta taaggctctt gcaaagtgaa ccctctcatc aggaatatca
    14281 ttgatcggtg agatgaaggc agagacagaa cccataacca caataataag cactgtcgca
    14341 tattccatat ttgaaggtaa aaagataatc aaaagcgcag caattgcaac taatattgct
    14401 aaaaatttaa tgggtaaatc cgttgattgc gtatataaaa gcagcaacac aagaaaggca
    14461 ccaagtaaaa caagcaaagc cttactcgcc ttttgcaatt tgtcaaataa ggtatctaac
    14521 atatcctatt tccttttttc cataatgtac aagccatatg acaatagcag ccaaatcatc
    14581 attgaaatta taaaaccata ggtaactcca atcaccccaa agcttctagc caaagaacca
    14641 gtgatggcta gtgaggagat aaaggataca acataaggta tcacaagcaa gtgctgcttt
    14701 ctgataatgg taatcaaatt atcaatataa gtggcaaagg tgctgataat ccctccaaaa
    14761 ataagaagca taaaatcaag ctggtaatgc cttaaatcaa taccataaac aagcgatagc
    14821 accggcagcc ccacaaaata gctagcaagc aagatagcta ggcttgctaa tagcagcact
    14881 agactgagac gacgctctaa ttgtgcaaag ctcttctcgt cctcttttga atggtaaatg
    14941 gccagctgag tgatcatagg ccttaaaaac aagaaaatca ggttaatcat aaaaataggc
    15001 ataaacaaaa tattaaattc tgtttgaaca ccggctggga tcagctgctt tgagtaaagc
    15061 tgctccaaaa caaacttggg ctggttgtag atataaatga gtaaaaaacc atttaaaaag
    15121 aggggaaagc tctccttcaa tagccctaag atgctttgag catcaatacg acgctcaagg
    15181 ctcgtaaagg aaactgaagg ggttatgtca aatagcacaa tacaagccac tgaaataaga
    15241 catatcacga tcaaagacag gactagctgc ttggtcagaa ccagacagag cgtaaagcca
    15301 agaatcacca gcatatttcg ataaaacaag gatttgccgg caatatctaa gcgctctctt
    15361 tgttgaaaca ttccttgaaa cacatcagaa atggcatctg tgcaacgata caagcaaatc
    15421 aaccaaatca ctagcccctt aaacccacta tagctcccca aataaatata gagcactgaa
    15481 atggctatca tcaagaaaca ggtgactagt cttgtataaa aatagtcttt gaagcggtac
    15541 ttgtgtaata tatccgttga ttggaaattt ctaatctgaa ataagccaat agtaatcagc
    15601 tgatttccaa tagcataggc aaagctaaag gtatctgaag ctgatttaga taagacccga
    15661 gacacaatca tcagtaaaat cactgatatt agtgctgtcg agctggttcc caacacattc
    15721 caaataaaaa tcgactgatc cgattgaatc ctactgctgg ttttcatctt cttcctgctt
    15781 ttccttctca ttaagggcta aatactgaat cattttttta agcttaatct ctgtccgaga
    15841 caatttttga gtgataaaaa attggttgat gatgagtaaa aaaatgattg atagaaaaac
    15901 aaaatttgcc ggcgattcaa agcctagcag ccttgaaaaa taaaccgcag catttggaaa
    15961 cagtgacagc aaaagcacta ttaaagagaa aaagagccaa aaaaagctat cttcaattaa
    16021 aattttggat ctgcgaatgc tatctagtat aaacatggct gtcaataatg caacaatgat
    16081 caaaatcagc tgtaacccaa taaacatcct cttacctctt tctaaagttt tgaattaaaa
    16141 taatcgaaat aaacatgtga accatgtatt taatagatct agaaagagtg aggtagcttt
    16201 gaccagccag cctatcattc atttgcacct gaacctcact caccctatag ccttgtcgaa
    16261 taagataaga gatcgtatca ggctctggag tatagttaat attagttgca aaaatcctga
    16321 tcagctcctg attaaacatt ctcataccag aggtcggatc ggtaatacgc tttcctgtgg
    16381 ttagcttgat aaaaaagcta ataaggctat tgcctatcat tctcaaggat ctattctttt
    16441 cagcactgac aaaccttgat ccaatgacac aatcagcacc agcattaatt gaatcgctca
    16501 aagcctcaat atactctggc aagtgttgac catctgcatc gaactggagt gctttagcat
    16561 atcccttttt aaaggcatat ttaaagcccg tctgaatagc accagataag ccaagatttt
    16621 ccggcaaatc aatgatattg taatggttat gatgacagat ctctgatgtc cgatccgaag
    16681 agccatcatt gataatcaca taatcatatt gaggaaaatg tcttttgata ttttccacta
    16741 ctttttcaat cgactcctct tcgttatatg ctggaatcat taccaataag tcttttttca
    16801 tatcgtcaaa tattctctct attcattcgt ctaaacgcgt ctttttagca atcgctttat
    16861 gatataacgg atagccttag ctggcccaat cacaatatat tttaaggctc cttttatacc
    16921 tcccatatag tcaaaatcga cataggtatg tggcacactg ccttcacgca ggtttaagag
    16981 cttattatca ataaatggtg tcaatagctt ttcatttctt gaaattctaa aatcatagtg
    17041 tctgtcccaa gcaatataaa ttaagagacg ttcaatggca tgcaggatcg aattttgaga
    17101 cagaggctct gctggaatat cagcctcact taggtctaag tcaaacaagg gctttaaggc
    17161 atcgtattta aaccaaacaa aggtgccata gctcatgaca aaggtatcca tcgtctgaaa
    17221 atcaatgcgt tttgtaagcc ccattgcctg ccaaagctga ttcatttcag gggcaataag
    17281 gtgctcattc caagcgtcaa caattttatt aaaacggaaa aaacttggaa tatctgctat
    17341 cacaataccg atagcatcag cagccagtgc tgttaggatt tgatccgccg gcttcaccat
    17401 catatcaatc aattcagtgc gccaggattg gcccgcccaa aaatctgctt cctttgattt
    17461 tttggtatga aaatgcccaa tataatcata ttgagacaat cgttccttta aggtcagcat
    17521 tggcaagaca tctcgaccga tatttcctgt caccaatatg tcagcacttg ccccgctttc
    17581 tcgtagaatt tctttaatct cagccttttt agccttgcta tcggtcgtta tgagcaagtc
    17641 ataatcaaaa tgaaaatgac taaatgcttc taaaaactct gacaataaat caacataaaa
    17701 aacatgaaga tgaacagcaa ttttcttgct ttgatcaatg cttatcggct gctctggcag
    17761 gtatttatgt gccagaagat acttagcatc tggtggatgg acctgcgaca tatgatccac
    17821 aatcaagctg gcagggtatg tcgttttttg gtcaataaaa tccaaaaggt aaggagcaat
    17881 gtgctggtta gcgtcaatag ccttaacctt gataaagggc acatggtgct ttaagatggc
    17941 tgtcggattg taataagaga aatccgcatg cagcatagag gacgagtcct ccttggtcgt
    18001 atcaaatacc gtcttgtatc gaaagccagc ctccacaaag acagtggtta ttctggtttc
    18061 ataattgtgg atcacatctt gaacgtctgt tagctcaacg atattttccc aaaactgcct
    18121 aaattcctta ctatgaacga gggatttttt gaagctgata aaatagctct gaatatgctc
    18181 tttaaaggcc ttggtcgctc gattgttggt catgccccag aaatcaactg cttcatctgc
    18241 ttcatatttg agataataag gcttcatatc ccaaagcgga ccaaagcagg tatcgttcat
    18301 aatcgtgatt gagtcaaagt caacaaggtg ctcacagcct aaggccttca taccatcatg
    18361 ccaagctgca aaatcatagc ctttattgtg tcgttgaata aactgatcca tcaaatgccg
    18421 ctgttcaagc tgctcaaggt cctcttgatg gatatcacta tttgaaataa agacaatctt
    18481 tgaaaacaag gctctcatct gttcgagctg gtaataaaca tgatcgctta ccttatgata
    18541 tttattgaaa tgcacataca ataatagacg cttcattttt tcctcctaaa aagctcaagc
    18601 agctttgata ggtacctcca acgacgtgag gtaaccacac aattgtattg atgggttagc
    18661 gcttcaacct cttgcctttg atgatcaagc tgctgctgta gctgatctat cttctctgcc
    18721 tgtagagcct cctgatctgc aagcgtctgt cgtaattgat gaatggtatg acttaattga
    18781 tgaatccgaa tttcattttt agcgtcctgc tttagtaatg cttttgcaat agcttccata
    18841 ttggctgtag ggtatttaga caaataggac agctgggtct ccaacaagcc ttgaatacgg
    18901 cccagcattt tttcctctgc tgccggcctt gaatctgaat tatccgtcat tcgataaaca
    18961 gtggtcgaat ccttcaaata ggctagagag gttgactgaa acagctctaa ttgtatgtca
    19021 aaagtgtcgt ctgacgtctc caaatcaatg cgttgattaa ctgccctcat cagatcagcc
    19081 tccaccagcc aggttgatga catggtcatt ccttttaaag caagcatttt ctcgtaggtg
    19141 tctgttaagg gagtaaagcc actttcaaag gcattgctct gaataagctt gccgtcagta
    19201 tctacaaaat caaagtcagt attagaccat tttgaatctg gtgagctatc cagcaaatca
    19261 acctgctttt gtagcttgag agtatcagtc caatagtcat caccatcaca tctggcaata
    19321 tactgtccct ttgcctccaa acaagccttg acccaggttc ttgcaatccc aagatttacc
    19381 tcattaacga tgagtcgtat acgatctgga aagctggctt gatagtccat gaggatctgt
    19441 ctggaatagt ctgttgaagc gtcgtcaatg acaataattt caacatcaaa gctggtctgt
    19501 tgggctaaaa agctgtctaa ggcctctgaa atccaaggcc ccttattata attggtgcaa
    19561 ataatagaaa cttttttcat aggatgcttt ctaatgacaa ttattgatta atgagccagc
    19621 taccatttct ttgatataag ccactggcag agtccaaagc agacaggtca tctggagcaa
    19681 tatcgtttcg ttgaagcacg actaatgggg aatgattagc tgttaaaaag agcagcattt
    19741 gcccgttttg atcgcgaaca gtcacctcaa gctttaattt gatatcattt aggtgtgaga
    19801 gctgacactg gtaggatatg ttcttatgac caggaccact tgtcggttga tcctgtgaat
    19861 tgtcattata tacccaaata ttgcggtcaa tatcagtcaa cgaaaaggca acataggtag
    19921 gctcgtcctt taagacatga taggaaatct caaaggaaat gggctcatct ggactaaggc
    19981 ttggcttaga ggtcaacctc acctctaact ggcttgccaa atcagacaca ggctcagcag
    20041 cagctccttg ctcagcattt ttcaattcag tattatcaac actgtattgg ttagcgacat
    20101 caaagggttc gccgtaagcc ttgacaaggc cattttcgat gaggactgcg cgattgcagt
    20161 attttttgac agcccccata tcatgggtca ctagtatagt agtcttgccg ctctccttgc
    20221 gctccatgaa gtagtcattg cattttcgtt gaaaggcctc atcaccaaca gctaacacct
    20281 catcaagaat cagcacatct ccctgtgcct tgatagcgac agaaaaagca agacgaacct
    20341 gcatgcctga ggaataattt tttaattttt gattcatgaa atcatgcagc tcagcaaagt
    20401 caacgatatc atcatacata tcatcaacct cttctgtggt aaagcccagc attgcgccat
    20461 tcatgtagac attttcacgc ccagtcaact caggattaaa gccaacacca agctcgatga
    20521 aggacaccat tttcccctca actgtgacct gtcctttttc tggaacataa atttgagaaa
    20581 taatttttaa taaggttgat tttccagagc catttcgtcc aacgatgcca aaaaaatccc
    20641 ccttatacac gtcaaagcta atatccctta gcacatgctg ctcggtatag cccttaatgc
    20701 ctttaaaacg gttaacaaga gcagtacgaa agctcttggt tgcctctgtt ggcagcttaa
    20761 aggacttact gacatgatca actgttactg caatttcttt attagccatt agataatctc
    20821 cgcaaacttc ttagcatttt tattaaacac tgctacccca agtgctaata ggacaaatgg
    20881 aatgaggtaa ggaatgatga tatagcacca atttgtcgac atttgccaaa tggtcacatt
    20941 agctctgtca atcagcagat accgcaaatc ttgaataatc tgtgctaaag gattaagcat
    21001 caaaatcttg gcagcaagag ggtgtcggtc aaacacaaag gtaatcgggt agatgatggg
    21061 agtcacatac atacctgcct gcaatagaac ctcccaaacc tgagccaaat cacgataata
    21121 aacaaagacg gtagaaagca tcaaggccac accaactgta agaacagcca gctcaacaaa
    21181 gagtggtaag gccagataag cgtgaggaga taaagtaact ccattgatag ctgcaaaaac
    21241 caaaaccact aataggttga ttgaaaagtt aatcaatgct cctaaaactg ctgaaaaaac
    21301 gatagtatgc tttgaaaaat tcaattttct aagcaggtct cctcgcgata caatagagac
    21361 cattcccata ctggttgctt ctgagaaaaa ggaccaaatc acattggcaa gtaaaagagc
    21421 aaccggaaaa tgaggaacgt caccaccagt tcgcaaaaac ctgataaaca ccaaatacat
    21481 gatggtaaac atcatcaaag gctttaagat agaccacaaa taaccaatag cactgccctg
    21541 ataccttagt ttaaagtctg ttttaacaag ctctttcaaa agaatacgat tctttttact
    21601 caataattcc attattcttt tctcctatag ccaaatttgg tcatgatcaa tgccataaaa
    21661 acaagggtat gaaaggcacg atttttccga aagccatacg ctttgaaatc agacagacgc
    21721 tgatagaaag gcctatccaa aagccctacg taagcctcaa tcaatcttct gtcagccgga
    21781 tttagctgca agtctagcaa ttgccttgct tgatgttgac tagaaacaat aagccaccaa
    21841 tacttctcta tgagcttatg gggcttacgc cactgcttca gtcgcttaga ccaggttctt
    21901 gcccctaaaa cattagcatc atgctgacga tagagctctg ttgccacatc tagatacaca
    21961 agctctccct gcgctgctgc aatcaaggct aaataccaat catgcatcac cacatgctca
    22021 cagctcaccc actgctctgc cagcgcgtga ttaatcatca tagtgccgcc tgtgactgtg
    22081 ttttcagtca actcctggac tagctgagta ttagcatgat gtgattgtgt ttggatcata
    22141 ctctcatgac gtacttctaa gtcttgattg accaccttta ggtctgtgta gactagtaag
    22201 ggctcgctta tcttgtgctt ttgcgcttct gccagagtaa gctctaattt attgtctaac
    22261 cacacatcgt cttggtcact gaaaaaataa atatctgcct tttcatatgt taaaagggtg
    22321 tgaaagcttc gaatcacacc gaggttttcc tgcacatcag cattaatcaa gcaaattctc
    22381 ggatcctttt tagcaaaagc ctgaatgatg gcaagcgttt tatcagtaga gccatcatct
    22441 ctgactaata aggtccaatc ctgcaccgtc tgcctttgaa tgctttgtat ttgctctgct
    22501 aaaaaccgcg ccccgttgta ggtagacatt aaaatattaa tcttcatcta aaaataaggc
    22561 ctcatactct cctacaattt tctcccaggt atattctttg gcaatgattt gcttagctct
    22621 ttctcccaaa tcagcaaacg attccttttg atcaaccctg ttaatcagtc cagtaaggct
    22681 gcccttttct tttgtccaat aaagggctgc tgttttagca actgattgat taaaggtcac
    22741 tcccaaaacc aaattaagct gggtatgggc tagggcctcc aaaagacctg gattggtacc
    22801 tccaacctca tgcccatgaa tataagcaaa agcatgctca cgaatataag ctaaaagctg
    22861 cttatcatac tgtgttccaa caaattttac acgcgcgtcc ttatcacagc cagttgcact
    22921 aaccagccgc tcaaaataag gatttttgtc atggttgcaa ataataacca aatcccgctg
    22981 agtagatgat gccataaact ctctaatggc tgtttcatag ttgttttcag gaacaaagcg
    23041 ccccaaaatc aaatagtatt ggttttctgt tatctcaaat gtttgaaagt aagttctgac
    23101 tttttcatct gatgtagaca aacaagaccg ccctatttct gtcccatagg caataaaagt
    23161 cgtttttgcc caaggataag actttttgat gtaggcttca atgccaatat tatctgagat
    23221 gaccaaatca gcatgctttg tcatttgctt ttcggcgtat ttcaggtatt gctgaacagg
    23281 cttagaccat tttgaacgct tccattccag cccatcagga ttaatcaaca aacgcccacc
    23341 acgctggtga atctgctttg caaagggggc aataaagcct ccaatggtat tgcctagaac
    23401 ataaaaaata ggcttttgaa tatgatacct atcaatataa gctaaagcgt gactaatagc
    23461 catcatatca taagcaatca ctctagctgg accgagctta ggaggattga tataaaaaca
    23521 atctgctccc ttgtacacaa aatgctcctt gtgcttgcta tcgctcaagc aggcaatatg
    23581 ataggtaatg cttttgttgg tctgattagt gactaattct tcaacaaagg tctcaaaacc
    23641 accatacttt gctggtaaac cgcgacttcc gatgatgaaa acatcctgca tagcacactg
    23701 ccccattcta aaatataatt agtagtatta taccatataa acaggtctta tgcgacataa
    23761 aatccatgaa aagagagcca atctcctaga tcagctcttt agtgctatcg cttattcatt
    23821 gctgttgctt gtaaaaagcc tccagggctt cttgccaggt aggaatcaca aaaccagttg
    23881 ccttagcctt atcaagattc atggttgagt taaagggtct tttggcttta gcaggaaaag
    23941 ccgatgaatc cacaggcaca acctcgacag ctgtctcttt taagatttct ctagcaaaat
    24001 cataccaagt ggtgtcttct ttagcatcat ttgacaaatg ataatagcca taaggcttgc
    24061 gattgtctgc tagatgacac ataaactcag ccaaggtcct cgtccaggtt ggacgcccat
    24121 gctgatcatt gacgactgtc aagcgagagt gggtcttagc aaggttttgc atggtaaaca
    24181 caaaattctt gccataatga ccaaacaccc atgcggtacg aataatgtaa aattgcttgg
    24241 tatatcgctc aacagccagc tcacctaagc gcttagcacg accgtatgct gtttgaggat
    24301 caggagtatc tgtttctagc cattcctgac cagctggctt ttgaccatca aaaacgtaat
    24361 ccgttgaaat ataaaccaag gtcgccccgt agcgctcaca agccttggca atatgctcag
    24421 taccagctac attgatagct tcattcagtg cttttccttc ttcttcagca gcatcaactg
    24481 ctgtgtaggc tgcacagtga tacactaagc taggcttgac ctgagcaaaa acctcctcta
    24541 ctttagtcgc gttggtaata tccatttcag caacatcaac agcaacataa tcgacgcttc
    24601 gttcgtctaa aagataacga agctctgttc ctaattgacc attacttcct gtaattaaaa
    24661 tcatcttttc tcctttgtaa aggtcttatt tctttgagct aatcacgcag ctcactccca
    24721 tctaatccta agagaggctt ttttgatcag ctgaccctag caagaccttt gttgtggtat
    24781 cgtatcagcc ttgcttttta tctagctacc gaatacctag ggcaattctc gcatagcggc
    24841 tcatcttttc aacgctccaa acagggtacc agaccaactt tacctcaacc ttggtcacct
    24901 ctggaacatc tctcatcgca tcatgaatat gatcagtcaa caaatccgcc aaaggacagc
    24961 ccattgtggt caaggtcatg tcaatctcgg tatgaccatt gtcatcaaaa cgaatctcat
    25021 agaccaagcc tagattcaca atatcaatac ctagctccgg atcaataacc gttcccaaag
    25081 cttcaagaat ccgatccttg atagctgcaa cctgctcttc tgtgtatttt aatgtttcag
    25141 tcatagctat tcctttcact tttttcgaag acctgatatg atgccaagtc aaaaaccagc
    25201 ccaaagacca gcgcattcag catacctatg atgccctaag ctgactaaca ttgatagcct
    25261 ctttttagtc acccttacat taacactagt ctttagctac tggctagcaa aggtaatctc
    25321 ataaaccagt aactaggctt ggagtcgttg accataggcc actcaccgtc aaggagagat
    25381 aacgcatttc gggctcgtct cctattttta gctcgccgtt aaaaaggtcc accggacctt
    25441 tttaatcctc aatgaagtct ctgagctgct tgctgcggct tgggtggcgg agcttacgca
    25501 aagccttagc ctcaatttga cgaatccgtt cacgagtgac attgaagacc ttcccaacgt
    25561 cctctaatgt acgcattttc ccatcatcaa gcccaaagcg caggcgaaga acattttcct
    25621 cacgatctgt cagcgtatca agcacttcgt ctaattgctc acgaagaacc acacgagttg
    25681 tgtaatcaac aggattttca atcacttcat cttcaataaa atcacctaaa tgactgtcat
    25741 cctcttcacc gattggtgtt tcaagagaca ctggctcctg agcgattttc agaatttcac
    25801 gcaccttatc aggggtcatc tccatacgct ctgcgatctg ctctggagta ggatcctgcc
    25861 ccaattcttg aaggaggttg cgctgctcac gcactagttt attaatggtt tccaccatat
    25921 gcacaggaat ccgaatggta cgtgcctgat ctgcaatagc acgagtaatg gcctgacgaa
    25981 tccaccaggt cgcataggtc gaaaacttga agcccttaga ataatcaaac ttgtcaacag
    26041 ccttcattaa gcccatgtta ccttcttgaa tcaaatcaag aaattgcatg ccacgcccta
    26101 cataacgctt tgcaatcgac accaccaaac gcagattggc ctcagcaaga cgctgcttag
    26161 cctccatatc accagcggct actgcaaccg ctaaaacctt ttcctcatca cttgtcagca
    26221 gcggcaccac accgatctcc ttgagataca tgcgcacagg atcgttgacc ttggctgaat
    26281 tacttccgat aagctcctcg tctgtcagct cctctggctt aggctcttca acgacgtatt
    26341 tagatgaggg atttccttcc ttatctgtaa tggaaatgcc accatctgtc aaacgctcaa
    26401 gcaaatcatc aatttggtca gcatctaagg taaatggaat cacgagtttt tctgtgacct
    26461 catcatcagt agctgttcct tcctttttat gatgacgaat aaactccgca atttgaacgt
    26521 taaaggttgt aatttctttt tcttttgcca tattttcctc tattccattt ttcttttttc
    26581 agcaatgaaa cgctctaaag cctctagagc catctggtgg tcacccttac tgctagattc
    26641 cctaatctgc tttccttgcc tatgcagctc tctttgcttt agcaatgtca tttgccttga
    26701 taaaatatcc tcaatctcac cgctagctat ctcatcagga agattttcct ctaaaacccg
    26761 gtaataggct tggttaacct cttcagacag ttgcgatagg tcataggagg taatctgccc
    26821 tgtggccttt agctgctcat acagcgtctg aagggctggt gtatcaaaat aaaaatccgg
    26881 ccgatgacga aattcattga gcaaatagtc gtgatgaagc aggcgatgca ggaggtgact
    26941 ttctgtttta gccaaggctg tcatgctttt gttaatcggt aaggtcacca gagatgcctt
    27001 tggttgacta gcctgtcctt gttgtaagct ttgcctatct tgtagcctta aagcatttac
    27061 cgattgctcc acctgaaaat aatcaaaatc cggcagcaaa tcagccacct tattaatata
    27121 cgaattttgt gcggtgattg agggtgcttg agcaataatc tgtgatatat gctccacata
    27181 agcaatctgc gattgcaggt tatccatatt ttcaggcttc aggtgatcaa tcaaaaactc
    27241 aacactgcta atgcgcgagt gctggagcaa ttctgctaga gcctctggtg aatgctgctg
    27301 aacaaattca tcgggatcca ttctatttgg tattttcacg atctccactt gaaaatctgc
    27361 cagcagctca agagacttgg caatagcatt ttgcccggcg tcgtcaccat cataagtcaa
    27421 tacaaccttt tgtgtcagct gcttgaggtg cctaacatgc tctggcgtca aggctgtccc
    27481 catagaggca acagtattac catagcctgc ccggtaggct gcaataacgt ccataaagcc
    27541 ttccatcaaa aagacctcat gagtcttagc gattatcggc ttggccttat caaggtggta
    27601 aagctcatag gacttgttaa ataggaccgt agcccttgaa tttttatact tggcctgctg
    27661 cttttctata tcctctcttg cccagatacg tcctgaaaaa gcaatcatat tgcccttatc
    27721 atcacataag ggaaacatga ttcgatgacg aaaggcatca taaatagcat ttgattgttc
    27781 agaaacatga aacaagcctg aggctgttaa ttgcgcctca gtatactttt ttgacaaggc
    27841 ttgataaagg tagtccatct cgttaggcgc caagccaatc cgaaaatact ctattagctg
    27901 atcatcaagc cctctttgat aaagatactc cttggctctt tggccaatct ttgtcgtcat
    27961 caaaaccgca tggtaaaact tagcagcatc ttcatgaaga tcaattaaag cctgatgagg
    28021 gtgctgcttt tgactcaaac tagtctgact tggagcaaca gtaactgcca taccagcctt
    28081 atcagccaca atctgaacac tttctaaaaa aggaacctgc cgatattcct caataaactt
    28141 aaaaacatcc cccgacttac cgcagccaaa gcagtgaaag aactgtctat cttcgatgac
    28201 attaaaagag ggtgtttttt ctttatgaaa gggacacaat ccaaggtagt gccgaccagc
    28261 ccgcgataga tggacaactt ctccaataac atcaacaata ttgacattat gcttgatctg
    28321 agaaatcatc tctttgtcaa tagccaaacc gtcacctccc cacaaaaagc ccattgtaaa
    28381 tttacatttc attataccat tgaaaatgag ctttgtaaat tgtaaaagca caatccttca
    28441 tcatctaaag cccgctacat caagcaataa gctatgctaa agtattgacg tctcttatga
    28501 tcactagctt gactagcagt acagcattaa gtagctcatc agtccttgat aagctcttct
    28561 attagccttt ttgacctatt tgtgctatga taagattatc tgaaaaaagg ggagtcaatc
    28621 atgctcaaag aattaaaagc atttttattt agagggaata ttatcgacct agcagttgcg
    28681 gtgattgttg ggagcgcctt tagcgctatt gtcacatcat ttgtcaacga cattatcaca
    28741 ccgctgatcc taaacccagc cttgaaagct gcaaatgtgg aaaacattgc tcagctcgcc
    28801 tggaatggca tcaaatatgg cagctttctc agtgctatta tcaacttttt aattgttggt
    28861 accagccttt tctttgtggt taaggtcgct caaaaagcaa tgcctaaaaa gggagaggaa
    28921 gagcccgcta agcccaaaac accaactcag gaagaattat tacttgacat acgtgatttg
    28981 ttagccaaaa aataactcaa agctcttaca gcagctggac ctgtccggct gctttttgat
    29041 atacaagcac agagcactta gcgatcaaaa gataatagaa ccggctctat ttgctgtttt
    29101 agcatatcat tgctattttt atcagcagca agctaaggta aaaaaagaca aactagtatc
    29161 ctcatactgg tttgccttca aactaaggca gcctacaaag ggccgccttt tttatgatga
    29221 ttagaatttt ttacgtttgc gagctgcttc tgatttgcgt ttacgcttta cagaaggttt
    29281 ttcgtagaat tcacgcttgc gtgattcttg aagagtacca gctttagtaa cagaacgttt
    29341 gaaacgacga agagcatcat caagcgattc attcttacgt actactgttt ttgacatatg
    29401 tttcacctcc tcaagatatt gtaacatttt cacgttctag cttatcttac atgatttttc
    29461 ggaaaaagtc aatgatcttt tcttgatttt gaggtcattc ttaaaaaaat accttaaaat
    29521 ttgctgctgc attaggcatc acttggcaag gctattctac tgcatttcct gttaataatg
    29581 ctgcttcttg aataaaggcc ttgtatttgc catccttgtt taattgcttg atcaccttat
    29641 taatggtttg ccttaggtca tcactcccct ttggcatagc tacagcctta gcatctccat
    29701 cacttgcctg caatttaaat ggtgctaaag ccaggtcttt atgttgagct aaaaagcctg
    29761 cagctactgg tgcttccaaa tcaacagcct gcacctgccc agatttcaac tcattaatag
    29821 cctcacccat cacagttaga gaaacacagt tggctttatt aagctgctcc ttgactaggc
    29881 cctcctcgat gctgcctttt tgaacagcca cctttttgcc aactaagcta tccttattag
    29941 cataatgctt ggcatctgac gctttcacca aaatagcatt ttcagtttca tagtaagcct
    30001 cagaaaaatc atacactttg gcacgctctt tggtgtagga caaaccagaa atcgctatat
    30061 ccaccttacc agtttgcaga ctggataaga cattatcaaa attcatagca gagagttcaa
    30121 gcttaacccc tagttcatca gcaatggcct gtgccagctc aatgtctgct ccgacaatag
    30181 tatccttgcc gtcaaccaag gccttaaatt caaaaggagc atagtcaggg ctaacagcaa
    30241 ccaccagctt tcccttttcc tggatcctgt cttgaaggct cgtcttgtta gcttggccac
    30301 aagctgccaa agcaaaaaca gataccatag caagtgctcc aactaataat cgcttcatgt
    30361 tcatattata attattcctt ttcttgttga tgaatcttat tatattgcat tattattcaa
    30421 tggtcaagtt tttattgaat atttttcaag cactgcgata gtctgcttaa tcctgcctgt
    30481 agaacctgcg gctgacagca atagccgatt ctcacatgat ttgcttgatt aaagcgattt
    30541 cccggaacga ccaaggtacc gtaatcctcc agcagcctca aagcaaaggc ttccatgtcc
    30601 tcatctatat ctagcctaac aaaggccgtt gagacctcat tcggtctatg gtaggaggcc
    30661 ctggcttcac ctgttatcca gtcctctaag atagcaaggt tagtcctgat aatggcttga
    30721 ttgcgctgca atagcttgtc agcatgcttc aaggctagcg aagccaccat atcatcaaaa
    30781 acacctgcac agatcattgt gtaatctcga tataacctaa gctgatcaca gatggtctca
    30841 gaagcggcta cccagccaac tcgaatgccc ggaatcgaaa aggtttttga catgctatta
    30901 acagtaatcc ccttatcata caaatctgcc accgctaaaa gatgatcaga ggtaaaggaa
    30961 tgataaacct catcacttag caggtaaata tcatgctctc tagcaatatt gatgagctcc
    31021 tctaaataag gcttggtcat ataggcacct gttgggttgt tggcattgtt gatcatgatc
    31081 atttttgtgt tgggacgaat catggcacct agctcattaa ggtctggcag ccaagcctgc
    31141 tcctctctga tctgccaata atcaacctcc actccaagag aagctggaat atcatatagc
    31201 tgctgatagc taggatagtg agcaatcaca tgatcacctg cttcaagcag tgcataaata
    31261 accaaaaaat tggcacctgt tgccccattg gtttgcaaga tatttctagc tttctgctgc
    31321 tgataaagcc ctgccactgc ctgcttaaag tcaggagagc cttctatcca gccatagtct
    31381 aatggctttt gatgcagctg ctggtaaaag gcttgaggct gctcctgtgt taagtcaaag
    31441 agctcctcaa gcgttaatga agcaatagat gagccagcaa tatcgtatac agcacgtttt
    31501 tcatgctgat ttagccactc ttctacacca aataccggta gtttcataag atcaccttat
    31561 ttcttgcgta atatttatta caatatcgca taaaaataca attgtcaaat caaaaactat
    31621 cctttttttg ataagaatca tgtcctatct aacagttagt cctgattggt ctcgcatgaa
    31681 aggctactaa atagagcaaa aatcacataa aaagactccc aacccaccaa tcagcgggat
    31741 taggagcctg atagctcgta tcaattcatt gatttcagat cagagtgact atcatcactc
    31801 tactatgagc caatgactag gctaggcgga caacttctag ctgtgatcca cccattaata
    31861 ccaagtattt ttcgatcctt gcaatcccgt aggattggct cagagcctcg gcatataggt
    31921 ccatttgctg ctgatagcgc tgcttcagct cagctgactg ctgatagcga tctgtcttat
    31981 agtcaaaaag aacaatacga tcctcaaaaa gcaggtagcc atcaataata ccacgcacta
    32041 cgtactgctc ctgacttagg ctgtcttttt tcagcatcgc aaaaggagcc tcgcggtgta
    32101 ggcgctggtg atgctcttgc aggagctgcc ccaattcagt tgtcgcaaaa aaagaggtta
    32161 ccttttcaat gtcaagcctt gccttgacct ctgcgtcagc tgagacaagc tgtaaggtct
    32221 gttcaatatc accagcagta acctgatcag acattggaat acgctgcatg agctcatgca
    32281 ggcttgagcc gacctggcta ggctcaacag cctttttctt agaaaaatca ggaagctcaa
    32341 aggtcttggg cctatgataa ggctgatcta tgatatcaac accatcagta tccattagag
    32401 gctcataaag ggttttaagc tgactggggg ttctcaccgt cggcagctca atggccgcct
    32461 gatagcttgc attgagctct gacaccttat ccagcatgtc taaggcacgc gcaatgtcct
    32521 ctgtttgacg gttatccttg agatcatctg cttgcagcag ccctgagggc cttagctgac
    32581 caacagcttc tggtgttaag tcactgtcat caacaaatcg cacatcaata aacaagtcct
    32641 ccttgctaaa tgttgctgct atcgctagta gccagtcttg aaagctcagc aatctttctc
    32701 gactagctaa ggctaagcgt ccttcggagc tattgtcggc tgttttttcc tgtacctttt
    32761 ccttgctagc cttaccaatg aggtatacct ttttttctgc tcgcgtcatg gccacataca
    32821 agagacgcat ttgctctgat aaggtcgcca agcgtagctg ctgcttattg agctggtaag
    32881 gaagagtttc catcgtaacc ttgagcgacg ccaatttttc ttctcttaga agctccttta
    32941 cattggcgac atatttgata ccgattccct catctctatt tagaatgatt ggcgcctgta
    33001 ggtcagccat cgcaaagcgc ttgtcgcaat tcaaaatgaa cacgtaatga aattcaagtc
    33061 cctttgattt atgaattgtc atgaggttaa cagcatgctt aggcctttcg acctcaacat
    33121 ctgccaaatc attttgcgtc tccagcacct tatcaatcat gccaataaag cgtgagagtc
    33181 ccttgtagcc tgattgctca aattggtcag cccgtatagc aagggcgtaa aggtttgcct
    33241 gagcctgctc tgcctttggc tggcttgcta caaagtcaaa gtaaaagcga tcgttaaaaa
    33301 tcttccaaat cagctcataa agcgaatgaa gctttgcaaa ttgacgccag tctctcaagg
    33361 tcccatcaaa atcagccagc tttgtcatca gctcctgacc gatcagctct gggtgctcgc
    33421 cttgtcctct caagctattg ctaagcttgt catagaaggc ttgaggctgc ttttgtgagc
    33481 tgccttgcag tgagattctt gccagctgat cctcatcaaa ggaaaacatt ggcgagcgca
    33541 ttaaggccac tagggcataa tcattcaaag gattgttgat gcttcttagc gtatccagca
    33601 tgaccatcac ctcaactgat ttgaggtaat tttcttggcc accatcagca acgagaggaa
    33661 tgccatactg attaaagacc tgaaaaatag tgtcatttcg tgtgcgtgac gaaacaagca
    33721 gggtaatatc ttcaaaagca accttctcct cgttatagag cctgatgatt tccttagcca
    33781 ctaagatgac ctcacctgcg gagataccat cgttagctaa ggcttcctcg gtgccttctt
    33841 gaacttgatc ggtgtcatag agcagcaatt gggctcgatt gttaggatat ggctgtcttt
    33901 gtccctcact gcctgctacc agctggtgct tgtcatcata ggtaatctct cctaaagact
    33961 cgtccataag gcggctaaag acagcgttgg tgacatttag gacctctgac tgactgcgga
    34021 aattttcctt tagtaaaatc agcttgccat gctcgggatt gctttgataa tccttaaact
    34081 tttgattgaa gatttgagga tctgcttgcc taaagcgata gatggattgc ttgatatccc
    34141 caaccataaa acgattatgg ccattagaca gcagctctaa taggcgctcc tgcatgtgat
    34201 tgttatcttg gtattcatca accatgacct catgataatg accttggtaa gcttggcgaa
    34261 tatctggagc ctgttgtaaa atctcaatgg caaaatgagc tatatctgaa aattcaaagg
    34321 cattttcttg catttttgca gccaaataag cctctgaaaa gctgatcaca aaggcttgca
    34381 gcacctccaa aagtggtaag ctctcctgtt gataagcaag gatagtctcc aagtgcctaa
    34441 atcttaccag ctgctcctgt agcgatttga aaatagggta tttgtgaccg gctacagtta
    34501 tatcagctcc tgaaggaagt aaagctgtta gctcctgtgc tagctgacct agtcgcgctt
    34561 taccgtaaag gctgtcaaaa tgcaaagccc actcatataa gctgtcaatc attttgaggt
    34621 gcttagtgta tttggcagtt agcttgccag ccttggttgt ttgagcgtaa ccctccatgt
    34681 ctgtgaggtc tcgcagctga tcagcagtgt cctgcataca ggctaagaga gcatctacag
    34741 cttggtctgg aatatctgta aagctggtat aggtcttaga ccctcgtaaa aagacctctg
    34801 ccaaccaact gctaggattg gcagttgatt gactgaaggc ataaatgcta tcaacaatct
    34861 ctctaaaggc tgagctatcc ttacgacgtc cagaaaaatt ctgcaccagc tgtataaagg
    34921 ctttattgtc agtctgcgac atatagtctt caaaaacctg acgaaagacc tcgcgcttta
    34981 aaatgtcctg ctctgcctta tcctgtatga tacgaaaatg cggtgaaatc cctaaaacat
    35041 aaccatgctg gtgaaccaat ttctgagcaa aggcatccat cgtaccaata tcagcctgtg
    35101 ataaagcctg caattggtca ttaaggtagg ccttgagctg ataatcctga gtctctgcta
    35161 tagctgtgtg cagctttttt tcaattctct ctattagctc agtagctgct tttacggtaa
    35221 aggtcgaaat aaataagcaa tcaaccggaa tacctcttag aatcttatcc aaaatgcgct
    35281 caaccataac aaaggtctta cctgagccag cagatgctga tactaagata ttttgtccac
    35341 tgctataaat agcctcaatc tgctgcgctg tccgcttgtg cgtcttatct gataaggcct
    35401 cctcctgctg caaacgagca atagcctctg gcgttagaaa gccttcatca atcctcatgc
    35461 tttatctcct cattcattcg tgtcaagaaa gcctgtctcc tttcttttgt cggtaggacg
    35521 actaggcgtc tcgcgtaccc tagatctaaa tccgcctcaa agcgcgtgat ggccttgagc
    35581 tggtcaccct gaacagactt gccgtctgcg gtataagggt ttattaggaa atgccctgtt
    35641 ttaatctgct tcaccgcaga caaatatagc tgctcattat aagccagcag ggtttctagc
    35701 tcatcagtct cataaagtgt gttgttaagg tgatagctgc cattagccag atattccttg
    35761 gcttgggcta aaaaaatgcc cttataggtt aactccttgt aagccgcagc tactagctga
    35821 tcatcaagtg ccttaaagtc agacagactt agccttggct cttgcatgtg caggtacatg
    35881 gcgccaaaca ggccctgccc cttattcttt agggcagcaa gataggtcac aagctgagga
    35941 ctcaagccat tgtaaaaggc aacaatgtca aatacccttg cactggattt gtagtccaca
    36001 atgcccagcc taccatcagc tagctggtca atacggtcaa taacccctcg aataagcact
    36061 tgctgaccca gcgctagctc aaaggcctcc tcttgcttgg ttatctgcag gccttgatta
    36121 aggtctaaga cagaggctgt tgagtaagca atccccttta ggacctctaa gctatatcgc
    36181 ccttcagcat cagcctgata aacctgctga aaagcgcttt gctgattaac tgctgcaata
    36241 gctgcgccta gcttttggtc aaaggcagca ttagacctat ccttggttac caactcaaaa
    36301 atacggtgca ggtattgacc atgaatgcga gcatctgggt gaatagactc tggctcttgc
    36361 agccctagga catatttcaa gaaatacttg tattgattgt tataaaatac agtcaaggcc
    36421 gatgaagaca gattcaaggg ctgctgactt gaaaagcggg tctcaataac ctcaggtgct
    36481 actggcttag tagtcaaatg atgctcaaaa gctggaagac ttagctgctc atcggctagc
    36541 ctacgtttca aataacgaag ggcaaccgtc caaaagtttc tgtcctcact ggtcatgtca
    36601 tctgcaattc cctgccgatt aatagccacc aagcgagaca agagagcctt ataattgcca
    36661 atatctgccg ctgagtgtga caaacggttc tttccttttt caatgactgg aacaccaagg
    36721 gcaattagct ccttcaggta aggagagaca tcatctgagc tattcgttaa gcttgtaggc
    36781 aggcttaaca ccagctcctg cgtcgctgca ttaaacaggg aaagtgctgt ttggtgattt
    36841 ttcttgatat tttcaaagct cggcacatca aggcgctggt aagaggcagt ctgctcattg
    36901 atgcttgccc tttcctgatc agagatcagg ctggtgtttt ttgtctgctt aggaaaatgg
    36961 gagcgactca ggccaatcgc aaacacaaag ggcttggaat gcggctccac cagatcatag
    37021 gatttgatag acacaacatc taaggtcgca ggcactgtcc gataatgtgc tgtctgcatg
    37081 cccatcttga tcagagctag acagtctgca agggtcattt tttcctgacc aaacacctga
    37141 taaaaggtct ctaaaatgcc tgtgaaggct ttccaaacct cctcgtcctt ttccctatca
    37201 gtctcccttc tactgcctgc tagtgcctca aaattatcag ccagctgaat ggtcttaaaa
    37261 aaggtcatta gcttatcaag tagggaagcc cctagctgct tttgactctt aaagagctgc
    37321 tggagaggag tcaccacagc aagtcgcagc tgattcaaaa gaggcaaagg atactgacgt
    37381 gaggaattta gggtaaaggg tcttgaaaat ttggtgaagc cttgaatatc agcaaagacc
    37441 aagtattgct caagctgatc cagctctccc tcttgaaagc gcccaaagag tcctgatttt
    37501 agtaagttga caatatcctc acgtcgccaa ttgtatctgc ggcctctttc taaggattcg
    37561 acaaattgaa ccaaggggtg agcagacatc ggctcttgct tgccgatata ataagggatc
    37621 tcaaatttct caaaaatagg accaatttgc agctgataag acgccacatc acctaaaagg
    37681 acaagcatat ccttatagcg ataaccctga tagagcttct cacgaatagc ctttgcaaca
    37741 tgctcaagct cctctttttg attgagcgct tgccagatca caaccttgct cttgtccttg
    37801 gcactgagct gccaatcaag ctttgaatag tcatgattgg cttcaagaag ctgtgttagg
    37861 cgagaaaatg acacatcaaa gaccttttct gacgttgtgt agatcggctt ggtttgaaat
    37921 tgctgtgcca gctgttggat aaacgcaagg ctcgcctcgt agagatttcc cttggtaaag
    37981 gctagtcgat aagccttttg actgatatag gctccaataa cgatttcttc acaggcttcg
    38041 tttaagagcg ctagcagctg ctcctcctca gctgaaaagc gggtaaagcc atcaatcact
    38101 aatacggtct gccttagctc gtcatctagg ctcttgcttt tgatagcctc agcaagctga
    38161 gccagcctac ttgactggtc gtaatctcct tgtgcaatca gctgctcagc cttggtcata
    38221 atcgtgatca ggtcctcttg cttttctggt ctatcaagcg tcgttaagtc aaaggctgtc
    38281 agattagctg cttgcaattc cttatatagc tcaactaact gggcaataaa ggcctgatct
    38341 gtccgtagcc ggtgaaaaac ctttagctca tcttcttgca gctgcatgag cacacgataa
    38401 aaaatcatgg ctaagccatt atcatctaac gcttgtcgat tagctgcctt agctaaggta
    38461 aaataacgcg ccatctgctc aaagcgggtc accgtaatag caaaggaacc ctgctctggc
    38521 aataaggcta ggacagaacg ttccttttca aaggatagag agttaggagc aatataaaag
    38581 acacgatagc ccttatcagc ataagctctt gcctctttga ctaaaatctc tgtcatggaa
    38641 tagctaatct ctgtgtatag taatttcata aaactccttt tatttggacc tgatacaacg
    38701 tctatgcctc cattataaca aatcagcctt gcttttccca ttgttaatga tctttcaaac
    38761 gccacaagaa gcgctcacag catgaaaaaa gcctaccatt tcacatctgc tgctttgcgc
    38821 aagaaatgat aaggctttgt cttgtatagg ctcaaaaaac agactaagag ctcctagtta
    38881 agctgccctg tgcttgtctc ttgtgatctg tccccaggca ttctttttac gctgataacc
    38941 aataaagctg ctcaccttga taagggttaa taccgtatga agaacaaggc attggtagat
    39001 ggcagcatag attacccaag ccatatcaaa aagagtaatg ctactattgt tttgcaaata
    39061 aaccctattt aaaaacgatg tcaacgcaat aagcacacaa tagcaaatat agagcagcat
    39121 cagtgacaca aaaaaggttg tgtttaattg atggcatagc aaagacagca caatgataat
    39181 aacaccaaat gcctcaataa aaggagataa aagctcaaac aaaagataca gcacatagga
    39241 aatgagtacc gtcgctttaa accgacagct tacaaaaaac tggagatact ttttcaagca
    39301 ttgatacagt cctaaaaacc aacgacgcct ttgccgacac aaatccttca agcgactggg
    39361 cgcttggctc cagcaaatag cgtctgtttc atagccaata cgataaggaa tcttgttgtt
    39421 atggcagaaa aaatgtaatt tcatcaccag ctccatatct tctcccagag tcccagtgtc
    39481 ataaccatca acagcaatcg caagctcttt tttaaacagt ccaaacgctc ctgatatgat
    39541 taaattccca gcagcctggt ctaataaaac acgagctcca aaaaaggcac aatcatactc
    39601 aattgcctgc gcacacgaaa taagctgacg cggcaaatgg tagtctacga tcctcccagc
    39661 tgccaatgct actccctgcg aaaccttgac catgccccca acagcaatga cagacggatc
    39721 ctttgcagca gtctttgcaa tacgcttaag cgaatcctcc tgtagcatcg aatcagcgtc
    39781 catgcacaat aaataatcgt attgagcagc gttaatccca agattgaggc tatctccttt
    39841 gccgccattt gccttttcaa gcagggtcag cttgatatgc ttgagctgct tttggcttac
    39901 agcctttaga gggcgtgttg ggatccgctg attaatcgaa caagtcaccg cttctaaatg
    39961 aaactgctcc ttcaagagct tggcggtatg atctgttgac ccatcatcaa tgacaataat
    40021 ctcatagcag tcataatcaa gcatcagcaa ggactccact gtttcgataa tggttagctc
    40081 ttcattatag gccggaacca aaatagacac tggcggtaaa gaaacatcac caccaacagg
    40141 cgcttgctgt cgcctttcat aaaggtgaat agtcccaaca attaaggata gcagtaaaaa
    40201 gctcgcatag gcaatcaaaa acgctaaaaa aagatattgg gagtatttca atactaaaaa
    40261 cagtagctgc actatcattc tcctttaaca tgcaatcact tgtgcttacc attcgcctta
    40321 caaaagcgtc tcaaggtctg cttcatcaaa tacccgatat taaaggcaag gatcgctaag
    40381 caaacgatta tataaaaaaa caacaggtaa taaatcatct tatcttctcc tcttttcctg
    40441 ccagacagcc tgcacctgct gataggaggt ctttaaaact tctcttaccc ttggacgctc
    40501 ccagctcaac agtggatact ctaccattgc aatgaccttt gattccttta gcggtgcaaa
    40561 accaatagct attgcttcaa tggctaattc ctcaacacca tagtgctcaa aataatcatc
    40621 gtgtattttg tttgaagctg gatcagaaaa attgagcagc tgccagggaa tcctaagctc
    40681 aatcagacgc tcgccaaaag aaatatcggt ctgcgaatca aaatgagccg agcctcgttt
    40741 gccattgccc tgttttaatt ggccggtagg gtagcgcttc agtcctcttt ttgcaatcgg
    40801 aacctgatca atggctgcaa aaataccatc atttctcacc accatatcaa ccatagtaaa
    40861 tcttggcgta tgcttgttag ggggaaagac ataaaagtcc tttccattaa tctgcctaag
    40921 gtaattggca tcagtagcat ggtagcgctc ctgcaccaag aggcgactgc ctttgtggtc
    40981 atcaacaaca agggcaaaat cagcaaagcg atcaaaccga gcgctaaagc cttcaataac
    41041 cctgctgcct gttttgggcg taatgtctaa gggaatgagc cactgtcttt gtaagggctg
    41101 cttttttgtc gattcaatag caatatagag gtatttttcg tcctgatcaa cgaggagctg
    41161 ctgcccattt ttcttgtagg ttagagctct agaccactca tctgctgcct tttgcccatc
    41221 aatagcatgc gtccttggag catgctcaaa ggttaagaga ccataacctt gagccttaga
    41281 ctgaacatca ccccaaagaa agctttgatg tttattggtt gcaaaggagg tattccagct
    41341 cctagcagtc caatcgtcct gccagctatg gatcgttgca ccacagcagc cagacgcaat
    41401 aaaggctgtg taatctgcca tcaagcgctc gccttgatcc ttttctgtca aagggctgga
    41461 agtcgatatc atttggtcca cacctctggc tgtcgaatag ccatagcccg tcacaaccac
    41521 tgggacacga tgatagctcg tcagtagctt gacgtatccc tgatataagg gcatgcgctt
    41581 aatatcccca acaagcctat cagtaagccc tagacggtca aatagcagat aatccctata
    41641 agccgagtga caatccaaga gcttatagga agcaaaaaga ccggccttaa ccttagcgct
    41701 gggcttaata ttttcaatcg tcagttgaac atattttgct gcctgagagg caaagggatc
    41761 ctgatagaca aagggatctg attgaggcgt atttgaaaag ctcaccaagt gctgccagcc
    41821 atatttgcgg ctctcgtatg acgtgatttc ctccatgatt tcagccagta tagcctcaaa
    41881 ccgattggcc tgaggtgtcg ttgcataata ccttccctta aagcctacag gcttggcgtg
    41941 attctgatga ttggtatagg ctatcgtccc actgtaccaa tcatcaccaa caatatagcc
    42001 gagtagccat ttactcatat cctgatcata atgctgaagc cctaaatccg aatgccagat
    42061 ccgttttctc ccatgaatca catcaacact agccctagct tcccttaaca gagtgcctaa
    42121 ataagcctta tctaaggcgc tgatagaaga attgtcatga taagcatcta ttctaaagcc
    42181 ctgtaatagg tacagaggat gacttgctct gtcattgtag cgtctcaaag catggtaaaa
    42241 agtgacgggc ataataaccc ttaccctgat cgtatttgca cccatagctg ctatttgctt
    42301 gaaccaccta tagtaggttt tctcatcaac gctaaggtct cgtcgacgat agcctgctat
    42361 ggaactctcc acatcaacac ccttgatgag ataaggagat cccttttgat catatatgcg
    42421 cttgtccttg gtgtaaaaga ctgtccgaat agctgactgg ttagagaccg gcaggtacaa
    42481 gcgaccatca atatcacaac aataatagct caagccaatc acagacaaga gcaaaccaac
    42541 aaagattaaa tatttcttca tcactaccta ctccaataat gtattggtat ttttagacgg
    42601 tgcactgtac tgatagagcg tctcaatatg cttatccagc catcgcccac gacgtctaat
    42661 aaagtccttt agttgcttaa cagaggcctc atagctactg tagttacgac tggctggcac
    42721 aaggtaatta gtggcatcgc ttcttgatgg cactgtaaac acatagcccc acttatgata
    42781 attgcgctga atagccggac ctaaaaaagc aaccgtagca tcaatatact tgatcaaata
    42841 atccgttgat aaaacattct gtcggagctg atgatacctt gtgaccacca gcttaacaaa
    42901 gctaggatcc tttagcagca tgcaaaacca aggagcatct gatagggtaa agtccgcctc
    42961 atcataagga gcctcaatct gattatcaaa ggcgttgtta aaatcccaga ccaccagctt
    43021 gagcttatcg cgcaaatcct tataaagata ggttgaaaac ttcccagcat caatatttct
    43081 aaagaattca ttgataataa aatagtctgc aaaggactct tggtccagat aatcagtgta
    43141 ttgctttaaa tcataagaat ataggagctt ttcgatatga ctgatatcct tttcaataaa
    43201 ctgcttttgc ttaggcgtca gacggtgcag gcttgggtat ttaatgtcta aagaggacag
    43261 acctgcttga ttcgtatagg atacgtaatg atcaagagcc tgcttagcct tgtgtcttct
    43321 atcccaaaca aggatataag gcgttttatc agattttcta tcactttttt cgatgtttac
    43381 cctatgccgc ccctgctcaa tactctccac agccaaatac agaccacaat actgatgatc
    43441 caccactaac tcgcaatacc tgacgttagg tgcataggtc atgatctcac cggcaatatt
    43501 gtagctaaga taatttcgga ctagggtccg atctaaaaaa ggaccatgca gcacccactc
    43561 agactccttg gacatgccag ccagcgagac tgcctttggc ttagctcttt tattgataaa
    43621 ccttagcttt aaggatttct tgtcaaaatg acgtgacgaa ttgcccctat aagcaatcaa
    43681 tgctgtcaag gacaagcgcg gagactcaga caggctgtgc tctctatcta gctgatcacg
    43741 aagcgagacc gtcgttttaa tggttttttg ccgctttgtc tctccctcgt attccctttg
    43801 ctctggaatc tgctgatgat gagtgtcaat gctaataatc ggcaaatgag agctaaactc
    43861 cccagtgctt ctggagctct ttttgaccgt ctgcaaatgg tgatgaatac gctttgcaga
    43921 ggtcttagga aaaccgatac cacaaatagc agctagcaag agacacacca gcacaatcac
    43981 ataaatcgtc ttttctttca tttacgtcaa ccagttatgt catcgctttg actaacaata
    44041 ttaaaataat caactcgccc cagctgataa acagcctcag ttaacggatt agcctgctga
    44101 taggtgctgt cataatcctt tcttgacagc tcaaagatca tctcaatatc atcagacgtg
    44161 gtgtttttca cgctctggat cgccttaccc gaaaagtagt taaacactaa ccgctccagc
    44221 tcaatttcca tttgcttatc acagcgaaca atcaacaaca gtctattgtc atttctgaca
    44281 gctcccataa gcaacaaaag cataaagatc acgctgctac cagttgcagc gacagtataa
    44341 tcaccaacac cacagcaaat cccaaccaca atcgtccaaa aaatatagac tgtatctcta
    44401 gagtctttga ttgctgtccg aaaacgcaca accgacagcg caccgaccat accaagagac
    44461 aaagcaacat tatttccgat aactgtcatg acggttgctg ttaagaccgt caaggtcatc
    44521 aacgaaacat taaacttctt gctataggca gtcccagtgt gggtataggc atatgacata
    44581 taaatcacaa tacttaacaa ggctgcagca acaatatgca gcaaaacatc ttgaaagctc
    44641 aaggtcccac gctgttcaaa gacatgtctt aataattgtt tcatcttaat atctctccta
    44701 aaaacgataa tgcttgctga tagctctccc catgcaatac ttgcttgcac ttagctcgct
    44761 accattaaca gactccaaaa gctttttgat ataagacaac aaaaagccat tatacttgac
    44821 ctccaagatg accaaatagg gatctagcag gtaattctga ggcagatgat ctgaaaaaat
    44881 atcagcattg gtctcagacc cgataatatg atgatcaaag gtaatgcgaa tattgttttc
    44941 ctttgccaca aatgccttgc gctggtattc gatcactgtt tttggctgat agagctgcat
    45001 tgacatgcga ctatagcatt cagcagcaaa gcgatcagga taagtcagca atatagactt
    45061 gtctccctta atcaacaatt gagcgtctgc tctggtcaac ctcagagatc gctttttttg
    45121 attgctccct tgcttttgct tcatctccaa cttagcaaat gagctctgac taccgtaatt
    45181 gcgcaggcga atttttcgcc taagctcaat accgtcctct ttttcctgcc agtcaacgtc
    45241 ctccaaagaa tcaaaataca aggatcgaat cacatatccc tcactagagc tatgagcatc
    45301 tagacgcaag agcttggaaa attcatgcga taagcgataa taatcctcaa tggtaatcaa
    45361 atactttttt tcttgacgca atacctcatt cacgccagtg tcctcctttt tcgtctgtaa
    45421 gcaatgcctt aacaccaagc tgcctgtaac agcagccaac aaacctgtct cataaataag
    45481 tcagggcaaa taaggtgatt gttggctcta caagagtcaa tcacctgcca aaatagtaaa
    45541 tcctgccatc tgttgaaata atataaacca gctgatcgtc ttgattgcaa gacaggcgct
    45601 tttgtgactg atctagctgt ctgctgctaa tatcagttgc attagcctcc ttgagcatgg
    45661 cctgcttgag ctgttgctgg atttttctgg cttgcagctc agaaatctca aagctgccat
    45721 taaccttttg agccttgtgc ttgtagacca gtgccacatg gtctttagct gttgtcctag
    45781 cagtcgacag gagcccttct ttgttgagct gagtatgctc tcctacatca atggcaacat
    45841 agtcataggg tgcccgtatc cggtgcgctg ttagtattga ggacaaaatc cctgtcacaa
    45901 ggcagatgct tatcgtagcc actatcatct gctgccgctg cttacgaatg aaccttgaaa
    45961 aagcacagac ctccgcctga tattcctgaa gctcttcttc aaccttactg taatcctgtc
    46021 taagatcagc caagtcagtc tgacagtcct tgcagcttgt cagatgagcc tcaacaaccg
    46081 ctctactata atcactcaac gtatcatcta catataatgg caacaaatcc tggatcaact
    46141 cacaatcata cttcatagcc atactcctct cgtaattgtc ttttaatatg ttttcttgcc
    46201 ctaaagacaa gaaccttggc agaggatact gtgatgccaa tatccttagc tattttttca
    46261 taggaatctc ccgaataaat cctcgccaga aagacagcct gcattttctc tggaagatta
    46321 aaaataatcg ttagtgtaat ctctaacagc tcccttcttg ctatcttatc aagtggttca
    46381 tcatgccctt tagcatcaac gatttctaag ctttccatcg acatattctc atattttttc
    46441 tttttaattt ctgtaaagaa ggtgttcttt gcaatggtaa ataaccatgt tttgattgaa
    46501 ctatccccac taaatttagc aatattacga taagccttta gaaaagtctc ttgagtaata
    46561 tcatctgata aactattttg ataacagcac agcttattta caaacctata aacatcatct
    46621 ttatattcta aatatatgtc ctcaaattcc aacagcttgt ctcctctcaa tacaccctta
    46681 accattagac cgtccaatct gccaaaagtt acagattaat ttaattttta gtataagctg
    46741 tcatcaagtc agataaatag taatgatcta tcatcttatt attgactcaa acgacaaatt
    46801 atattgcatt ttagtataag ctgtcatcaa gtcaggtaaa taacaaggac atatcatcta
    46861 acatttgatc cagacaaaaa agacctgatt ctgtaatata cagaaccaag tctttctcaa
    46921 tagacattga ctagatgatt gatttatagc gacatagcta gataggctat gacttaccgt
    46981 cttttggatt tggagacaag cccgccaaga cctgccaaga taccactgcc agcaagagcc
    47041 aataaagcat ctagctgact agtgcctgtt ttagggagag tcttagctga gaactgagaa
    47101 acctctccag cagtctgagc agcaactaat ttctcctgat gatgggctgc ttgatcagtc
    47161 attgcaccta aagtcccctt atcagactgg gacgccctaa gacggataat ggtagctgtt
    47221 aagcctgata gcttgacccc gtccttggtt agcacaaccc cctcaggact tgccagcgcc
    47281 tcggtgcctg cttgcttggc atcgacgata acctcaccag caagaagagc ctgaaactca
    47341 ccagttagcc taatggtacg gtcattgcta tcagcattga caaagacagc ataaacatca
    47401 ccattgcttg ctgttgtctg ataagcaatc accaaatcct gtgccttgat cccatgctca
    47461 tttggaacag tgatcagctt gaccttctgg tctatctcag ccttacttgc caagcgaaag
    47521 gcatctgtcg aacggcgcag cgcaatcaat cccttagtaa aggcctgact tgtcgtgctt
    47581 tcagggtagc gctctgtatc cgttgccttt gcccagtcaa aatgattaat ggcatctgtc
    47641 gaatcatagg aatcatgaat aaagtatggg tattcaaatg gtgttccgtc ctcattgacc
    47701 aagaggtgtg atttatttgg caccttgtca tcagcgacct tgcccttata ggcttcgtcc
    47761 ttaaattgct ttgtacgacc atattcctga ccagcatgta ggaaaggggt gccttgagag
    47821 gttagcacca agaggttccc taggcgcaag cgacgatgaa tctctgccgc atttgctgca
    47881 acagacggat cctttttaat agactgggcg ataatatcaa acaaggtcag gttatcatgt
    47941 gcagcgatat actgaatcac atcacccgga tcatcagcca aaaagttagt cggctgagcc
    48001 ttgatattat gaaaaatggt catgatatcc ctagcaccgc ccgtaataaa ggctggagag
    48061 ccttcatttg gaaagcctga tttgagctga ttgcgaaaat catctgagaa ggaggcaacg
    48121 gtatctgtct gtgacatcca gctttggtcc gcaggctgct caggcatgtg ctcatcaccc
    48181 tgataggtga cccagccctc accaagcatg atgatattcg gattaagtgc cttagctgct
    48241 aaaaaggctt tttcaatagc tgctgcatca tggtccccca tcatgtcaaa acgaaaacca
    48301 tcaaccttat actcatccac cagataagta atcgaatcca ccaaaacacg acgactcatg
    48361 taatgcgttg tcccaagtcg tccaccacca aatgaggtcc tagcagtgcc atcagcattc
    48421 ataaagtgat aataattcgg ctccaggtcc tcaaaaatat caacattagc tgtatgattg
    48481 tagaccacat caaggataac ccccatacca cgcttatgga tttcattaac aagctgctta
    48541 aattcctcaa tgcgcttagc tgggtcggtt ggatcagtcg aatacatacc agtcaaggca
    48601 aaatagcttt gtggatcata gccccagttg taattattat cacttgagct gtaggtcagc
    48661 atacgctcct tgttggccaa ttcgttgaca aaataatagc tcatcacagg cagcagttga
    48721 acatgcgtaa taccaagctc cttgagataa tccaactttt caacaaaggc agcaaaagtc
    48781 ccaaattgag cctttagatc attagcaatc gcctgatctg aggtaaaatc acgaacatgt
    48841 gcctcataga taatggcgtc ctcacgctta tgaaagccct taatatcagc aaaggccagc
    48901 tccttatccc caatagcagc aggatcaaca atggccgcct tagccacctt ataggacggg
    48961 tctgtcttag caagctcgct gttccatgcc gctaacgatt tggcataagg gtccagcaca
    49021 aggacagact tgccatttct agtaatctca taatgataga aatagcctct ataatctgaa
    49081 atcccaagtc cgctatctgc tgatagagtg attgaccact ctcccttatc accctttgct
    49141 agagcgagat taccaatcac cttggtctga tcagccttat catacaaaac aagtgacacc
    49201 ttatcagcac ttggtgacca aatcgtcaga tcaaccttag cacctgcttc tctcacacgc
    49261 gctcctagct caccgtcata agcatacagg ctatccttgt attgccaatt tggcctagcc
    49321 tggaagctct catgatgaaa ggtcaccgta taagtggcca ctgcttgact aaaatcacct
    49381 gtgatgacag ccttatgagt cttttcatct aaggtgatat cagtaatagc aactgcttcc
    49441 ttactgtcag tgctgatttt taattctttt aaaaggcttt ccttatccac atctgctaga
    49501 gtcgtaaagc tcgcctcaat actgcttggg ctgacctgct gagcaccgat taatctaact
    49561 gtattaacaa aataagggtt cgtataaatg gttggatcct cgtctttcaa gaaaatttgg
    49621 gtgtgattct ttaaatcttt aaaaatataa tcattgggct gaattttaac agcgtcacct
    49681 gtctgacgct catctagcaa gagaaagcct agctcattgg tatcagctag cttgacatct
    49741 atataagcac catatcgacc gacctgctta aaatcaatac catctggcca agcgccctgc
    49801 tgactagtca ttgacgcatc agcacttccc caaagccaga gcgatttgtt gtcataatgg
    49861 ccatcactgc gataataatt gatacggata tagccctgag ccagcggccg atagtaagac
    49921 agctcctggc catcaatcca gacctcattc atcttagggc tgagaaggtc tatggttcga
    49981 tcgcccgtca gattgtctcc cttagtgtta ttgatcaaaa agctaacctt attggcttga
    50041 ttggctgaaa gcttaacgtc catgtaatag ccatagtcat ctgtcttcgc tagactaaaa
    50101 ttggtagccc cagtcggcca gcctcccagc tgatcagatg gtgtctcaac atcgtcccac
    50161 acccaaagac caagcgagga taggtcttga gctggcaggg tcttgaaatg cagccgcaag
    50221 gtctgctccg ctatcggctc ctctgagctt gtagcttctg gtgtctctag agagctgtct
    50281 gtcgtaacag acactatcga tgatgaaggc tgagactggt ctgtagtttc ctcatgcgcc
    50341 tgatcctcta caagaggtac agctactggc tgaacttcct tgacagtatc agcattgaca
    50401 gcagctgaca ccttagtcac atcagaaata ccagcaatat cactaatgtc agtagcttct
    50461 ggtagctcat ttgagccttg gtcagcagcc tctgacttga ccatgaccgc accatcagca
    50521 ggctcaacac tcgtcagact ctcagctgct gctgtgatct gcccactagc tgtccccaaa
    50581 gaaaaagcgg ttgcaatagc taccgaagcc actccaagct taagcttacg aatgccaaat
    50641 aattgacgct cttcaaacag cgcttgattt tcccctaacc ttttcatcat tcctccgtcc
    50701 ttatcctgat agttattaac accttaagta tacaaaagaa atcacaatag tgcaatcgtt
    50761 ttctttattg aaaacaatga tatttatgaa caaattagac aagaatcaac gcaagcgatt
    50821 tccttactga taaatacctg ctcccctcac taagaccagc ccactgcaaa gcagaaaagt
    50881 agcctaaaga gccttagtaa cagataaatg agcttaatgt tgcttcatca actagctggc
    50941 tgcaaccgtt ttgctctgat gtggtaacgt cttgtcatca tgactaagct tgacaaaaaa
    51001 cgctgttagt tacataatca acggtgcttg gtagccttcc attactcctt tgattgttat
    51061 accctaatga tacacaaaac ctcagttttt atagtagaat attacacttt gttttgacaa
    51121 agatgtttaa tcttgctaaa ataaacttat caatgaggga gtaccaatga tgacattcga
    51181 attcacatcg ttattcgatt tacaaactgc ttttccaaca gagcaggctt gcataaatca
    51241 tttagaaaat atcacttggg gtgacgtggt gatcagccct tttgacgcta cctcaaaggt
    51301 ctataaatgc aagggaaata aataccgttg caagaataca gggaagtatt tcactgtcaa
    51361 aacaggtact ctttttgata atactaagat taagctacaa aaatggttta tggcaatctg
    51421 gcttgtgact tctcacaaga gaggaatctc ctcagtgcaa ttatcaaaag agattgcagt
    51481 gacacaaaaa acagcatggt tcatgttaca gcgtattcgt aaatgctttg gctctgaaaa
    51541 ctgagatcca cttggtgacg tcgttgaagt agataaaact gatattgatg gtaaaaataa
    51601 gaaccaccat gatcctaaga aggcaaaaac gttcaagaac catccttctc tgaaagataa
    51661 gtcggcagtt attggaatgg tgcaacaaaa aagtaaggcc aacgctcata caatactcgt
    51721 gattactctg atagtcggcg ttttatcttt tatcagctaa tgctgatatg cgaacaactt
    51781 ataaggagct gatcaatggt taaacatgca aaaactaacc tacactttga attagaaaga
    51841 tctatctctc gcaaagttga tagtaaattg atagcctatc aagtcagtct ttcagatggc
    51901 ttttatgaca aatacaccaa attatgggat aaaacctatt catttgattt tgtcatcaac
    51961 catcgtgcgt tttatgctca gttgaccaaa agatgtgttt acgatgtcct tttgcaaact
    52021 ttggaaaaaa tcagtagaaa agccattgca aagcaactag cagagcttga agccttggtt
    52081 gatgtttcgg aaagtaagga agactttcag atatttttcg agaaaaaata caaactatca
    52141 tttcctgatt tgaagaattg tgtttatcca aagaaaaagg aactttccga ttttgatcaa
    52201 aacctctgga tagctctaca ttataaccct agaaaggaga gggatacata atgacaacat
    52261 ggtatgatta catggtaaga gccagcgaac actctggaag tgatggagac ctctggtttc
    52321 gttaccttta caaggttatc aaagacaaag aaaccaaact aactactgat gatgtggagc
    52381 agttattaaa aaatccgaat ctaactcctt ttcagaaggt aactctgcaa gatgctttaa
    52441 cagaaggtac gcatacaaga gagcatgttt tacaggcaaa ccgtaaaagt cagccaaagg
    52501 atattttgaa actctttaga gagggaaact atggataaaa aaatcttatt caaagctctg
    52561 aatacagaac tagctaaaga aaatattagc cttgacatta tctgtgtcgg tggttttgtc
    52621 cttgaatatt acaatctgcg aggaacacaa gatatcgatg ccttttatca agaaggtgtt
    52681 aacatcaggc agatgatcaa aaaggtggga gatgagtttg gcgttaatga acctgatgag
    52741 ctttggctta ataattcagt tgccaatctt aatagaatac cacctaaaac gatttgtgag
    52801 acagtatttc actattctaa cctaattgtc cttgtcccac ccttgtctta tattcttgga
    52861 atgaagctag aaagcggacg agatagggat agacaagatg ccggagacat tattaagcta
    52921 gctaatatcc gttcccctaa aaaacttatc aatacacttg aagagtatga ttttcaacct
    52981 gatatttcaa tgattttaga agtctttgaa atagcttatg gcatggaatg gttagcaaac
    53041 tatatgaccg aacacccaga agaatttagg cattattaaa agacgatttc tgtttggaag
    53101 tcgccttttt tgatgttttt gaaaacacct tgagattagt ctaaactaat ctccataagc
    53161 aaaaaacagc ttagccccgt ctgggagtaa gctgtttttg ctgtaatgta tgagataatt
    53221 aggctaacat caatcattac ataaagggaa taaagggtta atgtttcttg cgtttgcgtg
    53281 atactacagc tacgcctaga cttgccaata cggcaagggc tgctgctgta aagaatggag
    53341 ctgttgcttc tcctgttgac ggaagcttgt gttccattgc tttaggtacc gctggtttat
    53401 ctcctttctg tgcttctggt ttaggcattg gtttagcctc tggcttaact tccggtttag
    53461 tttctggctt aggcattggt tttggtttag cctctggctc tggcttaggt tc
//
LOCUS       DARYLJ010000008        53323 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYLJ010000008 DARYLJ010000000
VERSION     DARYLJ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53323
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            74..394
                     /locus_tag="TU746_000418"
                     /pseudo
     CDS             74..394
                     /locus_tag="TU746_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            387..1907
                     /locus_tag="TU746_000419"
     CDS             387..1907
                     /locus_tag="TU746_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0890800.1"
                     /translation="MNRIAIYLRLSEEDYKKTDESVSIVNQRDYVRNYIENENSLKDC
                     EIEEYIDDGFSATNTNRPSFLRLIDNIKAGRINTIIVKDMSRFSRDYILLGDYLSNIL
                     PFLKIRFIAINDNYDSINEDGNGIDTDIQFKTLYYDLFSKELSEKVKSSFKQLKSQGK
                     NTNWAAPFGYIKDPKDKHHIILDEKTAFIVKEAFDLLLEGYSCNQVANIFNEKDYITC
                     SERKEELKISEYTRNLVTGSKINKRVWTSATISRITSNELYTGDYVYNKYKETKMGGR
                     KRILLPEEEWEIIHNTHEAIVSREVFDKVRIIKKKRIFGGYAKNREESVFSDKIFCKE
                     CGRHMGFRCDSRQKKNPNKVYKYRNYYCYFCKASRTPNNVKERDIIELIRPKLDEFKL
                     QNTEKDKKTMDYEKIKEEYLREISALNSNLQIIYENYKKNSISKEEYLRKKILVQDRK
                     KLLENKIKELENVEDDSKKELDINNLDEDNLLKIYVDNIIDKIIASRTGEIEIIEK"
     gene            1948..2562
                     /locus_tag="TU746_000420"
                     /pseudo
     CDS             1948..2562
                     /locus_tag="TU746_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            3092..3970
                     /gene="mvk"
                     /locus_tag="TU746_000421"
     CDS             3092..3970
                     /gene="mvk"
                     /locus_tag="TU746_000421"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL0890801.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            3952..4896
                     /gene="mvaD"
                     /locus_tag="TU746_000422"
     CDS             3952..4896
                     /gene="mvaD"
                     /locus_tag="TU746_000422"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL0890802.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            4889..5887
                     /locus_tag="TU746_000423"
     CDS             4889..5887
                     /locus_tag="TU746_000423"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL0890803.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            5890..6882
                     /locus_tag="TU746_000424"
     CDS             5890..6882
                     /locus_tag="TU746_000424"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL0890804.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(7167..8450)
                     /locus_tag="TU746_000425"
     CDS             complement(7167..8450)
                     /locus_tag="TU746_000425"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL0890805.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(8437..9612)
                     /locus_tag="TU746_000426"
     CDS             complement(8437..9612)
                     /locus_tag="TU746_000426"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL0890806.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            9797..10636
                     /locus_tag="TU746_000427"
     CDS             9797..10636
                     /locus_tag="TU746_000427"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL0890807.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            10717..11214
                     /locus_tag="TU746_000428"
     CDS             10717..11214
                     /locus_tag="TU746_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL0890808.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            11234..11404
                     /locus_tag="TU746_000429"
     CDS             11234..11404
                     /locus_tag="TU746_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890809.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            11440..12669
                     /gene="clpX"
                     /locus_tag="TU746_000430"
     CDS             11440..12669
                     /gene="clpX"
                     /locus_tag="TU746_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL0890810.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            12679..13278
                     /locus_tag="TU746_000431"
     CDS             12679..13278
                     /locus_tag="TU746_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL0890811.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            13642..16644
                     /locus_tag="TU746_000432"
     CDS             13642..16644
                     /locus_tag="TU746_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL0890812.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(16834..18927)
                     /locus_tag="TU746_000433"
     CDS             complement(16834..18927)
                     /locus_tag="TU746_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0890813.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            19298..19717
                     /gene="ndk"
                     /locus_tag="TU746_000434"
     CDS             19298..19717
                     /gene="ndk"
                     /locus_tag="TU746_000434"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL0890814.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            20218..21024
                     /locus_tag="TU746_000435"
     CDS             20218..21024
                     /locus_tag="TU746_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0890815.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(21316..22281)
                     /locus_tag="TU746_000436"
     CDS             complement(21316..22281)
                     /locus_tag="TU746_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL0890816.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            22453..23736
                     /locus_tag="TU746_000437"
     CDS             22453..23736
                     /locus_tag="TU746_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL0890817.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            23738..24598
                     /locus_tag="TU746_000438"
     CDS             23738..24598
                     /locus_tag="TU746_000438"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL0890818.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            24763..26022
                     /locus_tag="TU746_000439"
     CDS             24763..26022
                     /locus_tag="TU746_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL0890819.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            26022..26645
                     /gene="folE"
                     /locus_tag="TU746_000440"
     CDS             26022..26645
                     /gene="folE"
                     /locus_tag="TU746_000440"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL0890820.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            26653..27453
                     /gene="folP"
                     /locus_tag="TU746_000441"
     CDS             26653..27453
                     /gene="folP"
                     /locus_tag="TU746_000441"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL0890821.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            27460..27819
                     /gene="folB"
                     /locus_tag="TU746_000442"
     CDS             27460..27819
                     /gene="folB"
                     /locus_tag="TU746_000442"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL0890822.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            27816..28322
                     /gene="folK"
                     /locus_tag="TU746_000443"
     CDS             27816..28322
                     /gene="folK"
                     /locus_tag="TU746_000443"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL0890823.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            28418..29305
                     /gene="murB"
                     /locus_tag="TU746_000444"
     CDS             28418..29305
                     /gene="murB"
                     /locus_tag="TU746_000444"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL0890824.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            29351..30505
                     /locus_tag="TU746_000445"
     CDS             29351..30505
                     /locus_tag="TU746_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890825.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            30489..31283
                     /locus_tag="TU746_000446"
     CDS             30489..31283
                     /locus_tag="TU746_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890826.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            31280..32056
                     /locus_tag="TU746_000447"
     CDS             31280..32056
                     /locus_tag="TU746_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890827.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            32049..33122
                     /locus_tag="TU746_000448"
     CDS             32049..33122
                     /locus_tag="TU746_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0890828.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            33280..34812
                     /locus_tag="TU746_000449"
     CDS             33280..34812
                     /locus_tag="TU746_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL0890829.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            35018..35632
                     /locus_tag="TU746_000450"
     CDS             35018..35632
                     /locus_tag="TU746_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL0890830.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            35980..37107
                     /locus_tag="TU746_000451"
     CDS             35980..37107
                     /locus_tag="TU746_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL0890831.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            37259..37936
                     /gene="radC"
                     /locus_tag="TU746_000452"
     CDS             37259..37936
                     /gene="radC"
                     /locus_tag="TU746_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL0890832.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(37938..38633)
                     /locus_tag="TU746_000453"
     CDS             complement(37938..38633)
                     /locus_tag="TU746_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL0890833.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(38645..39289)
                     /locus_tag="TU746_000454"
     CDS             complement(38645..39289)
                     /locus_tag="TU746_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL0890834.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(39575..39922)
                     /locus_tag="TU746_000455"
     CDS             complement(39575..39922)
                     /locus_tag="TU746_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL0890835.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(39912..41039)
                     /locus_tag="TU746_000456"
     CDS             complement(39912..41039)
                     /locus_tag="TU746_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0890836.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(41042..42016)
                     /locus_tag="TU746_000457"
     CDS             complement(41042..42016)
                     /locus_tag="TU746_000457"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL0890837.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(42151..42723)
                     /locus_tag="TU746_000458"
     CDS             complement(42151..42723)
                     /locus_tag="TU746_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL0890838.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            42818..43489
                     /locus_tag="TU746_000459"
     CDS             42818..43489
                     /locus_tag="TU746_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL0890839.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            43464..44300
                     /locus_tag="TU746_000460"
     CDS             43464..44300
                     /locus_tag="TU746_000460"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL0890840.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            44297..45199
                     /locus_tag="TU746_000461"
     CDS             44297..45199
                     /locus_tag="TU746_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0890841.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            45203..46204
                     /gene="pta"
                     /locus_tag="TU746_000462"
     CDS             45203..46204
                     /gene="pta"
                     /locus_tag="TU746_000462"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL0890842.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            46304..47062
                     /locus_tag="TU746_000463"
     CDS             46304..47062
                     /locus_tag="TU746_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL0890843.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(47167..47853)
                     /locus_tag="TU746_000464"
     CDS             complement(47167..47853)
                     /locus_tag="TU746_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL0890844.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            48108..48836
                     /locus_tag="TU746_000465"
                     /pseudo
     CDS             48108..48836
                     /locus_tag="TU746_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            48829..50361
                     /locus_tag="TU746_000466"
                     /pseudo
     CDS             48829..50361
                     /locus_tag="TU746_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            50719..51702
                     /gene="guaC"
                     /locus_tag="TU746_000467"
     CDS             50719..51702
                     /gene="guaC"
                     /locus_tag="TU746_000467"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL0890845.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            51888..52469
                     /locus_tag="TU746_000468"
     CDS             51888..52469
                     /locus_tag="TU746_000468"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL0890846.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(52757..>53323)
                     /locus_tag="TU746_000469"
     CDS             complement(52757..>53323)
                     /locus_tag="TU746_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL0890847.1"
                     /translation="LDQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAAL
                     INLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQI
                     KDKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPE
                     VEGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        15340 a         9935 c        12149 g        15899 t
ORIGIN      
        1 ttcataactc aatgtcataa aaatagcccc ccaattgtta gattttatgt ctaacttttg
       61 gggggcagtt caatatgtta gaggagatgt tcttttaagg aaatttaaag cagaaagtaa
      121 taaaataaat ggacagataa aaacgataaa aaatgaatta aaggtagtag acgataaaaa
      181 gaggagcata aagagaagaa aagatgaact caaaaaattc atagaagccc tattttactg
      241 cttagaggat tacaagagta tagaggtgga taaagaactg gttgatacct taattaaccg
      301 tatagaaatc tcaaaataca agcaagtaac tatatacttt aaatttagtt ttgataaaga
      361 tatagaaaag cagttggagg tagagcatga atagaatagc catttattta agactttcag
      421 aagaagatta taaaaaaacg gatgaaagtg taagtatagt aaatcagaga gactatgtaa
      481 gaaattacat tgaaaatgag aactctctga aggattgtga gatagaagaa tatatagatg
      541 atggtttttc tgctacaaat acaaacagac cttcgttttt aagacttatt gataatataa
      601 aagctgggag aataaatacg ataattgtaa aggatatgtc gagattttca agagattata
      661 tattgcttgg agactatctg agtaatatat tgcccttttt gaaaatacgg tttattgcta
      721 tcaatgataa ctatgattcg ataaacgaag atggaaacgg gatagataca gatatacagt
      781 ttaagacctt gtattatgat ttattcagta aggaattatc ggaaaaagta aaaagttctt
      841 ttaaacaact caaatcacag ggcaagaata caaattgggc agcacctttt ggatatataa
      901 aagatccaaa agataaacat catattatac ttgatgaaaa gacagctttt atagtgaaag
      961 aagcttttga cttgctgtta gagggatatt cttgcaatca ggtagcaaat atattcaatg
     1021 aaaaagatta tataacctgt tctgaaagaa aagaagaact aaaaatttca gagtatacaa
     1081 gaaatcttgt tactggtagt aaaataaata aaagagtttg gacaagtgcg actatatcca
     1141 gaataacgag taatgaatta tatacaggag attatgtata taataaatac aaagaaacca
     1201 aaatgggagg aagaaaaaga atcttgcttc ctgaagaaga atgggaaata attcataata
     1261 ctcatgaagc gattgtttct agagaagttt ttgataaggt aaggataata aagaaaaaaa
     1321 gaattttcgg gggatacgca aaaaacagag aagaatctgt tttttctgac aagatttttt
     1381 gtaaagaatg cggtagacat atgggattta gatgtgatag taggcaaaag aaaaatccaa
     1441 ataaagtgta taaatataga aattactatt gttatttctg taaagctagt agaactccca
     1501 acaatgtcaa agaaagagac attatagagt tgataagacc aaaattagat gaatttaagt
     1561 tacaaaatac agaaaaagat aaaaaaacga tggattatga aaagataaag gaagagtatt
     1621 taagagaaat atctgcatta aatagtaact tgcaaataat ctatgagaat tacaagaaaa
     1681 atagtatttc aaaagaagaa tatttacgaa aaaaaattct tgttcaagac agaaagaagt
     1741 tactggaaaa caagataaaa gaattagaaa atgtagaaga tgattccaag aaagaactgg
     1801 atattaataa cttagatgaa gataatttgt tgaaaatata tgtagataat ataattgata
     1861 aaataattgc atcaagaact ggagaaatag agattataga gaaatagata attcaggaaa
     1921 ttctatatca attgcttgac attgtaggga aagtcctcta tcatgaattt gctgtatcgc
     1981 ttttatgatg tacaatcagg cctcattaca gttgatgggc aaaatattca ggagtattct
     2041 agagaaagcc tgcgttcaca gatgggtatt gtcttgcagg atccttattt gtttacagga
     2101 acgattgctt ctaatatcac gatgggaaat ccagcttatt cggatcagga tattttagat
     2161 gctttggaaa aggtcggagc ctcttcgatg attgctcgtc tggaaaaggg cattcatgag
     2221 cctgtctatg aaaaaggctc ctcttattca agtggcgagc ggcagctaat tgcttttgct
     2281 aggacattga ttgccgaccc taaaattttg atcttagatg aagcgacctc gcacattgat
     2341 actgagacag aggacatcat tcaacaggct atggaggtct taaagaaagg ccgaacaacc
     2401 tttatcattg cccatcgctt gtctaccatt caatctgcta atcaaatttt agtattggat
     2461 aaggggagga tcgtcgaaag aggaacacat caggaattgc tagatcagca aggcatttat
     2521 gctgaaatgt ccaagctaca agaaaaggtg gctgtacagt aatgcttttt agtgatagct
     2581 atcaaaaaat tccttttcta ggccgtgtta agcagcagta gtctgtgaag taggagctat
     2641 atttaggttt tgtgcctaag cctttaaggt ttttaagagg ctggattagg gcttaacatc
     2701 aataaaatca tatgtcactt tatcacagca tgttgtggtg aagtgttttt tgtgtcgtcc
     2761 tgctaaaggg aagatcctca cagtcagggc ttggctggct cctttatcag agtcagatca
     2821 ttcatacgta cttcctgtca ggcttggcta agttgaattg tatgttgaga tcagcatgtc
     2881 agcaatttat gctttgtgtc tgacttttag cagcttgtac atgaaatagg actaaaggac
     2941 acttgaattg atgaagaatc agcttaaaaa ccatttgtcc tagataggat aagaactgtc
     3001 taaaaggggg atagatcatc gcaattttta acaatttagt gtaaaatagt aaggtgaatg
     3061 ttttgatgaa ataaacgaaa agatttagga tatgaataag acaattggat atggcaaggc
     3121 acacagcaaa atcattttaa tgggtgagca ttctgtggtc tatggctacc ctgcgttggc
     3181 cttgccctta aaagatattg aagtgacctg ccggattttc cctgctgcaa agcccttagc
     3241 ctttgatttt tatgatccct tatcaacggc agtttatgca gccttggagc atttggggtg
     3301 cttggcagag cccattcatt atgatattat gtctcaggta ccacaaaagc ggggcatggg
     3361 ctcctcagca gctgtttcga ttgcagctgt tcgagctgtt ttttcttatt ttgggcagcc
     3421 cttgtcagat gagctgttgg aaatcttggt gaataaggca gaaatcattg ctcacaccaa
     3481 tcccagtggc ctagatgcta agacctgcct cagtgataag gccatcaaat ttattagaaa
     3541 tgttggtttt gataccattg atattcagtt aaatgcttat ttggtcattg ctgatacagg
     3601 gattcagggg catacgcgtg aggctgtcaa taaggtggct caatttgagg aggaaaatct
     3661 tcctcattta gccaagcttg gctgtttcac agaggctgtt gagcaagcaa ttaagacaaa
     3721 cgattgccta gctattggac gattcatgac gcaggcacat gaatcactaa aggctattgg
     3781 tgtcagtgtg gcaaaggctg atcagctggt tgcagcagct cttgaggctg gcgctttagg
     3841 agctaaaatg actggtggtg gcttaggagg atgtatgatt gcattagctg aaaggataac
     3901 agacgctcag caaatcagta agaaactaaa agaagaggga gctgtaaata cgtggattca
     3961 aatactgtaa cggtaacttc ctacgctaat attgctattg tcaaatactg ggggaaaaaa
     4021 gatgaggcta agatgatccc atcaacctct agtatttctt tgaccttgga aggcatgtac
     4081 acgacaacaa gtctttcttt tttgcctgcc tcagcaaagg gagatcagtt ttatatcaat
     4141 ggtgttctgc aggacgccaa ggagcatgct aagattactg cgattttgga tcagttccgt
     4201 cagaaggacc agacttttgt caaggttgaa gccagcaaca gcatgccaac tgcggcaggc
     4261 ttatcctcaa gctctagtgg cttatctgct ctggtaaagg cctgcaatca gctttttcaa
     4321 gctaagctaa gtcaagaaga gcttgcccaa aaggctaagt ttgcctctgg ctctgcttcg
     4381 cgttcttttt ttggccctgt tgctgcctgg gataaggata caggctctat ttataaggtc
     4441 aaaacagatt taaagctggc catgattatg ctggtcttga acgatgctag aaagcccatt
     4501 tcgagtcgag aggggatgaa gcgctgcagc acaacctcaa caagctttga ccagtggctg
     4561 gcccagtcag aaagtgatta tcaggccatg ttgcgtgccc ttagtgacaa tgattttgaa
     4621 acggttggtt ggctgacaga agcaaatgct ctagccatgc acgcaacgac caaaacagcc
     4681 agtccttcct tctcttacct aacagaggcc tcctatcagg ccatgctaag ggtcaaagag
     4741 cttcgtcaag agggctattc ttgctatttt acgatggacg ctggtccaaa tgtcaaggtg
     4801 ctttgtttag aagaggactt agagcggctg tcgcaccttt ttgaaaggga gtatcgtatc
     4861 atcgcctcaa aaacaaagga attaccagat gtctaaatat catgttcaag caggaggaaa
     4921 gctgtatctg acaggcgaat atgcgattct aaggccgggg caaacggcgt tgatttgcta
     4981 tattcccata atgctgacag ctgtcattga agcagcagag gctgttagta tcagctcaga
     5041 tatgtttgac catgctgctg atttgtcacc ggataaggat tataggctga ttcaagcctc
     5101 tattgaagcc tttagtttat atatagataa ggatattaag gagctgccag ccttttcttt
     5161 gtctattact ggtaagcttg agcgtgacgg taaaaagttt gggattggct ctagcggtag
     5221 tgttgttgta ctaacgctaa gagctttggc agccttttat caggttcagc tgctaccaga
     5281 gcagctcttt aagctggctg cttataccct gcttaaatca ggagataatg gctccatggg
     5341 ggacattgcc tgcattgcct atgagagctt ggttgcttat acatcctttg ataggcgtaa
     5401 ggttggtcaa tggttgatcg agatgaccct aaaagagcta atggcagcac attgggggta
     5461 tacgattgag actattgagc ctgctctgcc ctgttggttt cttgttggct ggacccaagt
     5521 cccttctatc tcaagagaga tgattcagct ggttaacaag agcattagct gtcagttttt
     5581 agagcaaagc cagctggtca cacaggaagt gatgactgcc ctgcagcttg gtcaaagaaa
     5641 aaggctcaaa gctagcattg aaaaagcggg tcagttgctg caagggttgg cttcagttat
     5701 ttatcaccct aagcttacgc agcttgtcca ggcttgtcaa gggcttgatg ctgctgccaa
     5761 atcatcaggc tcaggaggtg gggattgtgg tattgcactc gtttttgagg ctaaggacat
     5821 tgagcctatc cttgccagat ggcagcaagc agggattgta ttactatatc aggaggaatg
     5881 gggataaaca tgactaatcg taaggatgac catatcacac atgctttgag ctatcattct
     5941 ccttacaatg catttgacga catggagctc attcactgtt ccttgccgag ctatgattta
     6001 gctgatattg atctctcaac ccattttgct ggctgtgatt ttgagtttcc tttttatatc
     6061 aatgcgatga caggtggtag caagaaaggc caagcagtca atgaaaagct ggccaaagtg
     6121 gctgcggcta caggtatttt aatggtgaca ggctcttaca gtgcagcctt gaaaaatcct
     6181 gaggacactt cctttcaatt gcgaggtgta gcaccagatt tacagttggc caccaacatt
     6241 ggtcttgata aggctgttga cctagggatt agagctgtcg aggaaatgaa gcccttgttt
     6301 ttacaggtac atgtgaatgc catgcaggag ctgttaatgc cagagggaga gcgcagcttt
     6361 aagcattgga aggatcattt agcggcctat gccaagcagc ttccagtccc tttgatttta
     6421 aaagaggttg gctttggtat ggatattaag accatcacta tagcacgtga tatgggagta
     6481 aaaacctttg atatttcagg aagaggagga acctcctttg cctacatcga aaatcaaaga
     6541 ggaagtaatc gctcttacct agacgattgg ggacagacaa cagtgcaatg tctattaaac
     6601 gccaaaggtc tggttgatga agtggagatc ttagcctcag gtggtgtcag acacccctta
     6661 gatatggtta aatgcttggt gctgggggca cgtgctgtgg gcctatcgcg agtggtattg
     6721 gagttagttg agacctatcc agttgagcag atcatcgcta cgatcaatag ctggaagaag
     6781 gagcttaagc tcatcatgtg tgctttagat tgtcgaacct tgagcgattt gcgtcaggtg
     6841 gattatttat tatatggtag gctttatcag gcaaaccgct aaagactttt tagccctgag
     6901 ctaactttcc ttagaaaatc atcacaggag ttaagaagct gcctgcttgg tgctgcaagc
     6961 taattcagct gattatggct cgtaagattt ttagatgtct gaatgaaatg ataggacaga
     7021 tgacatagta tagcgctaat ttctagtgaa aatcagtcct tggtcaggtt actgagactg
     7081 aggttaagtt tatgtttaca ctaacactta aaggatatga aaacacttgg tagctgccac
     7141 tgaagctgtt accaagtgtt tttagtctat gattggctta atcgtatggc tgttaagagc
     7201 tgtcctgcct tttctaggtt cattggctta tcctttagta gagccttaac tagttgaggc
     7261 acctcctgct cactagcacc tgctaataga gctagagact tggcctgcag cttcatgtga
     7321 ccagcctgga taccagttga ggtcaaagcc tttagagccg caaaattttg cgccagccca
     7381 actgcagtgg tgatttgggc gagaacctta gcatttggtt gctctaaaag gctatgagca
     7441 acactgacgg ttgggttgag accgatcgac cctcctttac tagcaatggg cattggcagt
     7501 gttagctctc cgcataagct atttttagat aaatcaacgt gccagctact tagccctcta
     7561 taagagccag tccttgcggc ataggcatgt gctccagcct caatagctct ccagtcattt
     7621 ccggtagcta tagctaccgc atcgattcca ttaaagattc ccttattatg cgttgctgct
     7681 cggtaagggt caatctgggc taatttgctt gccagctcta tttttttggc caattgctga
     7741 gcttcttcct tatgtcgact taggtatctg aggtcaacct gacatttagc actaactaaa
     7801 gcttttgttg catagtttga gaggatagcc attaagcatt gaccaccgct tagggcctcc
     7861 aaatcaggta ctaaagcctc catcatcgtg ttaacgatgt tggctcccat agcctcttgg
     7921 gtatcaacgc tcagatagac aatgaaaaaa tcctccttac gctcaacggt aaggctcttt
     7981 gcgccaccac cacgcttaac aatagaaggg taggcattgt ttgcaacgtc aatcaatgta
     8041 tctgcgttag ctagaatagc cagcctagcc tgctcgtcat ctttaacatc ataaagagct
     8101 acctgcccaa gcatttgacg actgagtacc tcagtctgaa agccacctga tcgcttgatg
     8161 attttggcag caaaggaagc agcagcaaca acagaaggct cttcagtcac aaaggggacc
     8221 tgataggtat gcccattgat cagaaaatca ggggctagac taaaaggcag agccagtcga
     8281 ccgatgacat tttcggtcat ttgattggca atagcaatgg gtaagagctg gtctgtctct
     8341 aacagctttt gctgctgcgg gccaagcagc tggtcatctg cgagctgttg aatgcgttct
     8401 gcaaggcttt ttttataaaa gccggcccaa tttggtttag tttttgtcat catcttgata
     8461 aattcgttgg tgttccttaa tttctttgag ggcaaacctg ccagttagat atggtgaaaa
     8521 gctggcattg ccatcttggt ctagtctagg ctcttcataa aaaagtgctt cataatcagc
     8581 cactgaaatc acctgacgtt ggtctaatag ggcttgtcga ttagtcagta gcatgtcctt
     8641 gtaaccgtca acaagctgcc ctgaaaacag ctcactaaca gctcctgagc catagctaaa
     8701 caatccaatc ctatcaccag cccttagcac ctgactattc tctaaaagtg ataataagcc
     8761 gaggtagagt gagcctgtgt aaatgttgcc gatttgcttg ctgtaggcaa tagaagcttg
     8821 aaagttttca taaagccttt ctttgtgatc atctgctagt gattttgtca tgatcttatg
     8881 aagtcccttt agagcaagct ttggaaaggg gatatgaaaa caaacagcag caaggtctga
     8941 tagctcaata ccttcttttt cttggtattt gtcccaggtt gtttttaggg aatcaaggta
     9001 ttgcttggtc gaataaatac cattgacaaa tggtgttgag ctgtaatttg gacgccaaaa
     9061 atccatcaca tcacgtgtct gtgcgacatt gtcatgattt aactggagaa tacgaggatt
     9121 agtagtaact agcatagcaa tacttccagc accttgtgtt ggctctccgg cggatccaat
     9181 gccgtatttg gcgatgtcac tggcaatgac caagaccttg gaggctgggt gtgcagcaac
     9241 atgtaatttg gcataatcta aagcagcagt agcgctgtag caggcttcct ttatctcaaa
     9301 ggagcgtgca aagggctgaa tatcaagcag ctgatgaacg taaatactgg ctgcctttga
     9361 ttgatcaatg cttgattcgg ttgctaaaat gaccatgtca atgcttgctt tatcgtcttt
     9421 ggtaaggatt tggtcagcag ctgatgcagc aagcgttaca atatcctctg taacaggtgc
     9481 aatgcttaga gcgtcaagca ttagcccctg atgaaatttt gctggatcag tgctgcgagc
     9541 aagtgccagg tcttccattt ttaagacgta ttgactggtc gcaaagccaa tcttatcaat
     9601 tccgatgttc ataaatatcc ttcttttatc cattttatag tcctatccat tttatcatat
     9661 tttcttagaa aattagctga tttaatacga tagttttacc tttcaaacca aaaacagcag
     9721 catatagctt tcttctggta tttttgaagg aaattagata aaataatatg gactgtgctt
     9781 acagaaaggg gtttccatga caaaagcaga tcatattttt aaagctaata tcaaaaaaat
     9841 tatggaggag ggagtcttta gcgagcaggc tcgcccaagg tataaaaatg gtcaaacagc
     9901 caattccaaa tacattacag gtgcttttgc agagtatgat ttgtctaagg gagagtttcc
     9961 tattacaact ctaagatcaa tccctatcaa gtcagctatt aaagagttat tttggattta
    10021 tcaggaccaa tcaaacagcc ttgatgtttt agaaaacaaa tacaacgttc actattggaa
    10081 tgagtgggag gtcggtcaga caagaaccat cggtcagcgc tacggtgcaa tcgttaaaaa
    10141 gcatgatatc atctcaaaaa tcctcaagca gctagaggac aacccttgga atcgccgaaa
    10201 tgtgatttct ctgtgggatt acgaagcctt tgaagaatca gaaggactgc taccatgtgc
    10261 ctttcaggtg atgtttgatg ttaggcgagt agatggtgag ctgtatttag atgccacgct
    10321 gacccagcgc tcaaatgata tgctagtggc tcatcatatc aatgccatgc aatatgttgc
    10381 cctgcagcta atgattgcca agcattttgg ctggaaggct ggtaagttct tttattttgt
    10441 caataatttg cacatctatg acaaccaatt tgcgcaagcc aaggagctat tggagcgtca
    10501 gccagcagcc tgtcagccca agcttttgct gcatgttcct gatgggacag acttttttga
    10561 tataagacca gaggattttg agctacagga ttattaccca gtgaagcctc agctcacctt
    10621 tgacttggcg atttaagcga aaaagacgat tttttctgag cattttgcca agaaatttga
    10681 tagaataaaa gaagttcata ttgaggaaag ctagtgatga caaagaagat tattgctatt
    10741 tgggcagagg atgaagcagg acttatcgga gcgtgtggca ggcttccttg gtacctacca
    10801 aaagagttgc agcatttcaa ggaaacaaca ttgaatcaag ctatcctgat gggacgagta
    10861 acctttgagg gcatgaaggg tcgtttgctg ccaaatcgcc aaacgcttgt tatgaccaga
    10921 gacagttatt atcatgtgga gggcgcttta accataacca gtgtgcagga ggctttggat
    10981 tggtatcatg cgcaggataa gaccttatat gtgattggtg gcagcaaggt tttagaggcc
    11041 tttgatggtt attttgatgt catcatcaaa acagtggtac atcaccagtt tgagggtgat
    11101 acctaccgac ctaggttaga gctgagtgat tttgtagagg agacctctgt attgtaccca
    11161 agggacgata acaatcctta cgatttcact gttacagtat tgagacatcg ctaatatagg
    11221 gagatgatag tctatgcagc gtagtatttt tggggtattt acggcctttt tgtgtgcgat
    11281 ttgtgtttta tgtgccatac cggcctttag aaaaaatcgc tatggcttag gattactttt
    11341 tttattaaat gcctttacta acctagtgaa taccatacat gccttttatg gaacactgtt
    11401 ttaagcctaa gagaatgaaa agagaaagat agaggaatca tggcaggaaa tcgtagtaac
    11461 gatattaagg ttcattgctc gttttgcggc aagagccaag acgaagtgaa aaaaattatt
    11521 gcaggtaata acgtctttat ttgtaacgaa tgtgttgcct tatcacaaga aatcatcaag
    11581 gaagaattgg cagaagaggt tctcgctgat ctgactgagg taccaaagcc aaaagagctg
    11641 cttgagattt taaatcaata cgtcattggg caggagcgtg ctaagagagc cttatcagtt
    11701 gcagtttaca accactacaa gaggatttca tttactgaga gtcgtgatga tgatgatgtg
    11761 gatttgcaga agtccaatat tctgatgatt ggaccaacag gctcaggaaa gacctttttg
    11821 gcacagaccc tggctaagag tctgaatgtt ccgtttgcta ttgctgatgc aacctctttg
    11881 actgaggcag gctatgtcgg agaagatgtg gaaaatatcc tcctgaaatt aattcaagcc
    11941 gctgattaca atgttgagcg tgcagagcgc ggcattattt atgttgacga aattgataaa
    12001 atcgctaaaa aaggtgagaa tgtctctatc actcgtgacg tatcaggaga aggtgtccaa
    12061 caagccttgc taaaaatcat tgaaggaacg gttgctagtg ttccaccgca aggtggtcgt
    12121 aagcacccaa accaagagat ggtacagatt gataccaaaa atatcttgtt tatcgtcgga
    12181 ggcgcctttg atggtatcga agaaattgtc aagcagcgct tgggagaaaa gatcattggc
    12241 tttgggcaaa atagtcgaaa gattgatgac aatgcttcct atatgcagga gatcattgct
    12301 gaggatattc aaaaatttgg tctgattccc gaatttattg gacgcttgcc tgttgtggca
    12361 gcgcttgagc agcttaatac tgaggatttg attcgtattt taacagagcc tagaaatgcc
    12421 cttgtgaagc aatatcaagc cttattgtca tatgatggcg tagagcttga gtttgaaaag
    12481 ggggctctgg aggctattgc aggtagggct attgagcgca agactggtgc gcgtggtctg
    12541 aggtctatta ttgaagaaac catgctggat atcatgtttg aggtgccaag ccaagaggaa
    12601 gtaatcaagg tacgcattac taaggaagct gtcgaaggtc aatcaaagcc tattttagag
    12661 atagcctaag gaggtatgat gtctgaagag caaatcctta acacgcataa tgcttcgata
    12721 ttgcttagtg cggcaaataa gtctcattac ccacaagacg accttcctga gattgctttg
    12781 gcaggtcggt caaatgttgg aaaatcaagc tttatcaata ctatactagg acgtaaaagc
    12841 cttgctagaa cctcaagcaa acctggtaaa actcagcttc ttaatttttt taacgttgat
    12901 gataagctaa ggcttgttga cgttcctggc tatggttatg ctaaggtatc taaggcagag
    12961 cgggctagat ggggaaagat gatcgaagag tacctgacca cacgacaaaa tctcagagca
    13021 gttgttagtc tggttgattt tcgccatgag tcatcacagg acgacattca gatgtatgag
    13081 tttttgaagt attatgagat tccggtgatt attgtggcta caaaggcaga caaggttcct
    13141 cgtggtcgct ggaataagca tgagtctatg gttaaaaagt ccttaaactt tgatcaaaca
    13201 gatgcgttta ttattttttc atctgttgag cgtatcggta ttgatgagtc ttgggatacc
    13261 attttagagt atttataagc atatggtaaa aaatttaagt atcttttaga caggcacttg
    13321 tgtctggtct gagaggtgct tttttattga caaaaaaaca atttgttgat gacgagcttg
    13381 tgttcaaaaa tgtcagtttg ctaaaaaatg atgataacaa acaagacttt tatgatataa
    13441 tgcttagcag gataatatgg agacatgaga aaaaggtcag agacagctaa tttgctatcc
    13501 ctgattataa ctatgatgac cagcattatt ataatactca tggtgctagc tattagtagc
    13561 agcacctaac ctatagtgtt gctttttagg ttacaagcac tggcgctagg agtattataa
    13621 tatatttaga aaggtttttt tatgacaata aaaaaatgcc ctcaaatact tgccttattc
    13681 cttgcttttg cagcgctagc tagtcagggg caaaccgtcc atgctctgga gcggcaggag
    13741 acatctgtca agcaagctca tgaatcagat gattggtttg atgaggacga aggagttagc
    13801 gatatcaagt ctaatacccc tacagagata gactcaacag taacagagtt atttggtgat
    13861 gctgagccta agactaaggc tgaaaaagaa gagtcaaaag ctccaagccc taagcaagaa
    13921 gcactgccag cagagtctca aaaagaaaaa gagacatctg ctaaatcgac tgaccatgcg
    13981 acagtacaag cagaagaggc acagcctgag caaggctcag atagtccttg gctagcagat
    14041 gactttgtta ctaagggaga taccttggtt gggctatcta aggcaggtct tgctaagtta
    14101 tcaaagacac ctgtcttggt actaccaagg atagggattg acaagacagt gttgacaagg
    14161 attgctagct ttgcctttac tccaaataaa tcagtcgcta ttgctgatta tacaggtaga
    14221 gcaggtgaac atggcgagat caatcatctg gacgtcgaag gcagagatat ccttactgag
    14281 ggagaggatt ttggtgccta tgcgattaaa aagcttgtga ttcctgaagg ctatcttttt
    14341 atcggtcaag atgcctttaa tgacaataaa cagctagaag aaatcagtct acctgatagc
    14401 ttactcagta tttcagacta tgcctttgct cacatgagtt tatctaagct taagctgcca
    14461 aaaagcctac agtccattgg agatcaagcc ttttttgata atcggattgc aggcactttg
    14521 gtattgccaa aagctctaaa gcagctggga gaacgcgtct ttaagtccaa tcgcctcact
    14581 ggacttgtct ttgagggaga aggcttgtct gtcctaaaag aagcagcctt tcaagacaat
    14641 gctttcatta gtcttgttat cccagatagc attcaagcct tagaagagga cgtctttaca
    14701 ggaaaccttg gcgatgaaga atacggtaat catgccgttt tacgaaccaa aaatggtcag
    14761 aatccttaca gacttcacag tgccaatgtt cttgtcaatc caagtgatca ggctagaaca
    14821 ccacagccac caattgatta caacaggtgg cttgcagaag attttaccta tactggacag
    14881 acgataaccg gtttttcagc tagtggactg cgcaaggtca aacgcaataa gcatttggtt
    14941 ctgcctaaga attatcaggg tcagcccttg acagccattg cagataatgc ctttagaaat
    15001 gtcaattttc atgataaaac cttgcgtaaa tacgacctag aaagcgtgac gttaccatct
    15061 accattcaaa agattggtgc ctttgccttt cagtcaaata atctagaaag ctttgaggcc
    15121 agcgaggact tggttgagat tggtcaagga gcctttatga ataatcgcat tgagattctg
    15181 gccttgaatg ataagctgaa ggtcattgga gatgcggcct ttcatatcaa tcggatttat
    15241 gctattgtta tccctgagtc ggtcgaagta attggcattt ctgcctttag gcaaaatggt
    15301 gctaaacatg tgatgtttat gggagataag ctaataagta ttggagaaat ggcttttttg
    15361 agcaatactc tggaggaagt ggatttgagc agcttagcag ggcttaagac catcgctgtt
    15421 caagcctttg cagacaatca cttgagagag cttaagctgc cagatagttt gatgcgtatt
    15481 gaagcagaag cttttaaaat taatagactt caaagagtga ccgttccaga cactgtcatt
    15541 agcattagct ttaatgcctt tgatcataat agtgatgaca aggttgtcct aaggaccacc
    15601 aatcacaata aaaacctgct agctgatgga aatggcttta ttgtggatcc agacctatta
    15661 agtgcggatc aatcgactgt tcaagcagtt ttagaggacc tgcggcgctt agatctagct
    15721 agtctacgtg ctgatacagc agctcatttt atgacactca tcacaagagg taagcagcta
    15781 ctaaaagaat ccgctgtacg gttaggttat cagcttaggt tccttgcaga gtcacgattt
    15841 ttcttagggc gcgtgagact ggatcagctg attaaaactg ctgacataac cctatctagc
    15901 catcaagaca cacctaatgc taagctgttg atggctaagc tagacaaggc caagctgcat
    15961 tacaataata gcgcaatgac tgctccaaaa gtaagtcgct tggaaaaaga gctcagcctg
    16021 ttaattgatc ttgtccaagg ggtaggcgct atctctaaag caacaatgac tcaaggtgtc
    16081 tataagcttc agacaaccct acctattcca gagtattata ttggggttaa tctttatact
    16141 gatgatcagg ggaatatttt atttgtgctt gacatgagtg atacgattgg gcagggacaa
    16201 cttgatgact atggcaatcc tattttaaat gttgatgagg ataatgaagg ctaccatgct
    16261 ttggccattg agtccttagc agattacgaa ggccttacga ttaaggatat attgaccaag
    16321 gagctaaatc aattgcctat tcgcgatgtc aagcaagcaa gagagcatcg tgttggtctt
    16381 tttatggcaa tcagagatgc tgcaagggaa gctcagcttc tactagaaaa gcagagcaaa
    16441 gccttatcag aatcagccgg caaatctaat ggctcaaaag tagctgactc aggacttgag
    16501 ccttctgtga cactatcaac caataagact aagctgctac caaaaacagg agccttcaaa
    16561 gaagcttggg tgacaatgat cggaatgctt gttcttttgg cggctaccct acttaaaggc
    16621 gatagtcgct acaaaaagaa gtaaataggc ttgcttagca agcacactct agcaccagta
    16681 aggcttgagg ggcttacaaa gcctatctaa tctagcaata gtatattgcc agtgtgagct
    16741 ggtgcttgag cttcaaaaaa acaaaagagc ctgaaatgac ttttactagc atttcaggct
    16801 ctttttagct tgtgattctt ttttgtgtga agcttacttc tcacttatcg taatagtatc
    16861 ttgatcaagg cttgctaata ggtgtttagc agtcgggtga tccaggtagt aatccgtaat
    16921 gcggtcacga atttcttgtt cgatgacacg tctaagtgga cgaactccca tcgcatgatc
    16981 atagcccaga tcaatcaaac gctctttaac atcgtcagtc acctcaaggc taatgccttt
    17041 tttagcaagg gtttggttca cttctgttag cattaaagca acaatttctt gtaaatcctt
    17101 tttcgctaaa tggttgaatt cgatgacacc gttgaagcga ttcaagaatt ctggtctaaa
    17161 gtaaggtgca atacgctcca tgatagcagg ctcttgatca gcacgatctc ctgcttgatg
    17221 gccaaaacca gcattagagg ttgcgatgat aaccgtattt ttgaaattga tcgtgttgcc
    17281 ttgtccatct gtcaatcgcc catcatcaag cacttgaaga agcagtgtaa tgacctgtgg
    17341 gtctgctttt tcgatttcat caagcaagat gatagagtaa ggactgcgac ggacacgttc
    17401 tgtaagggta ttttgattat catcatagcc aacatagcca gctgttgttc cgattaattt
    17461 ggaaacagct gtgcggtcac tatattcaga catatctaag cgaatgatag cgtcctttga
    17521 gccgaacata tcaagggcta actgcttagc cagctcggtc ttaccaacac cagttggacc
    17581 aacaaagagg aaggagccaa ttgggcgatt accgtcatca aagcctgcgc ggttgcgtcg
    17641 aatcgcacga gcaacagcct caactgcacc atcttgtccg ataacatggc ctttaagacg
    17701 gttactgatt tccttgagcc tttctaaatc actagccccc atatttgata ctggaacacc
    17761 agttagacgt tcaacagatt ctgcaatatc attaacagtg gcagtgacct tttgcccttc
    17821 actgtgatga ttgatttgct tttggagctc ctcaatgcgg gtcttagcag ttaaggcctt
    17881 ttcaaagtct tcttctgcaa cagccttttc ctgtagctcc ttttgcttag tgatttctgc
    17941 ttcaagtgat tttagatcag tgacagggtg ctgagctgct agatgagcag cagtcatatc
    18001 aacaaggtca atggctttat ctggtaggct tcgttgtgga atatattgga tagcataatc
    18061 aatagctgcc ttcaagacag agtctggtag gatcacattg tggtgctgct cgtagaggtt
    18121 gcgaatgccc attaaaatgt ggaaggtatc ctctgctgaa ggagcattaa ccttaacctc
    18181 gttgaaacga cgagcaagag cagcattttt tagaatggtg ttgcgatact catcttgagt
    18241 tgtggcacca atcagggtca actcaccgcg tgagagggct ggttttagaa tatcagctaa
    18301 gcccttagag cctgagtctg aaccagctga ccctgcacca aggatttgat ggatttcgtc
    18361 aaagaagaga atgatattgc cagcctcctt aacctcttta accatgtttt gaatgttttc
    18421 ttcaaaggag ccacgatact gtgtgccagc ctcaaggcca gaaatatcaa ttgagataat
    18481 ctctttattt ttgatggcag ctggcacatc accgttgaca atagcctggg ctaggccttc
    18541 gacaacagca gttttaccaa caccagcgtc accgacaaga acagggttat tcttggttcg
    18601 tcttgctaga atttctgcgg tcgcttgaat ctcatcgttt cgtccgatca caggatctaa
    18661 cctgccttgc cgagcttctt cggtcaggtt tgttccgagc ttggttagaa tgccgtcttt
    18721 tttaaggctg ctagcctgtt tttcttgtcc ctcagctgca gctagcttac cggttttccg
    18781 gtattcttga aattcctctg gtgtcatctc acgtccattg acaagatagc gacgattttc
    18841 gctgcggtag ccgccgatgt ttcccattaa ctgattgaaa atatcgtcca tattttcaaa
    18901 ggggtctttt ccataatagg ttgccatata cacttacctc acttgtatta tatttaccag
    18961 tcattatgag ctactggtat aggtagaagg tgatcggtgt tggctcatac agagatcata
    19021 gagaggtctt atgagagtct attgctcagg cttattactc accttctaat aatattatat
    19081 ccaaaaggtc agtaaaggtc aaacaaaaag tatgaataat taacctttat aatcaggtgc
    19141 ttatagccct tgaaacatca gatgactatg ccataagctg ctggtgcttt tttgctagca
    19201 aggctatctg taaagaagag acttttgtca aaaatggttt tactttttgt tctaaaggct
    19261 ttcatgatat aataaaagaa aagcacagag gtcaattatg gaacaaacat tttttatggt
    19321 gaagcctgat ggtgtgaaac gtggcttggt tggagagatt ctacgccgga ttgagcgtcg
    19381 tggctttacc tttgataggc ttgaattgcg acaagcaacc ccagaattgc tagctaagca
    19441 ttatgacacc ttaatcaata agccctttta tccagagcta gaggcctata tgacaagcgg
    19501 acctgtttta atcggcatta tctccggtaa tcgtgtggtc tcttcctggc gaaccatgat
    19561 gggggtaacc aatcctaaag acgctttacc ggggactatt cgtggtgatt ttgctcaagc
    19621 ccctggtgat gatggcggca ttttcaacgt ggtgcatggt tcggattcga gagattcagc
    19681 caagcgagaa attgcgatct ggtttggaca tagctgacat tgggcttggg cctattcttt
    19741 taagaactga taaagcaatt gcataaggag ttgataagcc catcatcaat agtagctcag
    19801 cattagaagg gtaacagcct tgatgttggg ctattttttt gcttgcctag ggtctgtatg
    19861 cttgtcctga tgagcaggta gacaaagcag cataagttta acaatccttt gcggcagtga
    19921 tcaattgtag ctctaaccat agcatcagct atttgaaagc cttgaaaaag aaagctaagg
    19981 ctaacaagct agtctaggtc atttactaca agcgactttt ttcaattagc tgctcaaggc
    20041 aagtattgaa aaaagtccat ttttcatgtc atttgtaata atatggtata tttttaacga
    20101 aaagtcgttt tagttgagaa aatatacaaa aaaggctatg atatagttaa taaagttgtt
    20161 ataccccctg tgtcttgtac actatgactt gtagagagtt tatcaaagga ggataagatg
    20221 aacaaacaaa gcatgaccca tttttctaag aagctgatga agttagccct tttaggtttg
    20281 gcattgccat taagcttggt gtcggtggta gatactccgg ttcttaacca atccgaaaaa
    20341 gctgtttatg ccaatgattt tggatctgga aatcgagcca gtgattatgt accggcggct
    20401 aacgcttgga gctttgaggc ttatccagat tactacagta ttttaggagc tagtcatctt
    20461 aatcctgctg tctttccaga gcctagtaag atgtcataca gtcctttaga cgagttgggc
    20521 cgcacacagg tcgcaagagg aacaataacc tatcacaata tcgtgatgaa ttacaatgtt
    20581 cggcaacgct ttgctaaaaa tcagaaccct tcaggctgga ttggtaaccc tagaaatgtt
    20641 cgctacacta ttgagtggct agatggacta tcctatcagg gagatttttg gaatcggagt
    20701 catttgattg cagatagcct tggtggagca gccttacgtg tcaatgctat tactggtaca
    20761 agaacacaaa atgttggcgg cagaaatcaa agaggcggta tgcgctatat tgagcaaaag
    20821 gtgcagcagt ggattgagca gcatacaagc gcagttgttt attacgaagc ggtgccaatt
    20881 taccaggcaa atgagctagt tccaagagct gttgttgttt cagcattgtc atcagacgga
    20941 ggtcttgacg aaaaggtcat ggtctataat accgccaacg gctataccat tgattatgcc
    21001 actggcgcat tccgcagtaa ctaggctttt gtactaagct gtagctgatc aaggtctgac
    21061 taagacaagc tcatcagcaa ttggtatata aaaagacgtg gcaacaacat gttttaaatg
    21121 agttgtcatg tctttttagt gtcgtcagct tttcacattg tcttagaatg atcacaccta
    21181 gctagccgct aaaagcattg gtccaaagaa atgttaagaa tagatagaat gccttttaat
    21241 cagtggtatg ggactgctag ctaatataat gcctgcagtt gagccaattt ctcatctagg
    21301 ctaataacta acaagctatt gacttatcgt gttcattaga atgtcagctg ttgtagttgg
    21361 tagtattcga atacgattaa gcgatagcag gccattagca gcacttgcta gtccttcatt
    21421 tgttgtgacc cctaatttgt aatgcagatc ctcagcaatc tttaatgtgg tatcagtata
    21481 acgacctgct ggataggcaa ttgcaatggt atcttggtgt agctctctat ctaggtattc
    21541 tttagaatct ttcatttcag cggtttgact agcagcgctt gcctgagata gatcagggtg
    21601 gttaaccgta tgatcttgga aagacatgcc tgcctgcttc atttccttca tctgatccaa
    21661 tgtaagattg gccgcattac ctgcctctgt aaagccagtg ataacgttat tggtggcctt
    21721 gatgtcatac tttttcagga ttggaaaagc aacgttgtaa aaatcaacca tgctatcatc
    21781 aaaggttagc cagacaacct tttcagcagg aagctcgtta gctgataaga ctcggtaggc
    21841 ttcttcggga gataaaaagt agtagccggc ctccttcatt gcctttagct ggctttcaaa
    21901 aagatctgga gcaacgatga gattggcact tgctgcctct tctggtgcca taacgtgaat
    21961 agcatgatac attaagatag gaagcttaac agggttttgc tgcttggtcc agctgacagc
    22021 tcctttttgc tgctgactat ttgtatggct agcttcctta ttagttgctt ttttgctagg
    22081 cttgggagct ggttttttat cagtttttga aaataggctt attttgggga ttgcctgcga
    22141 taattgagag atgcttatct ttgaatggct cttgtaaagg tagacaatag ctgataagcc
    22201 tatgatacag gcaagtagta gcatgagatt aatcattttg aagatttttc ttttcttacg
    22261 ccgtttgttt ctgttgttca tcacttgctc cttgtttatt gattagtcta ttgtaacatt
    22321 tttttaagta agctgtcttt cgttaactta attttttgct aacattctat tagtgttatg
    22381 ctttgtaaaa caagacctag atttgctata ataagacaga gtatttaaga cagtcaaaaa
    22441 aaggaggata ggatgtcagt taaggttgca ttattaggct ttgggactgt tgctagtggc
    22501 attcccttgc tattagaaaa caatagtagc aagattcgtg cagtggtagg tgatgatttg
    22561 gtgattgcaa aggttctggt tagagatgag accactaaga agcgtttgtt ggatcaaggc
    22621 tattcctacc aatttgtgac ctccattgat gatattgttg atgatgagag cattgatatg
    22681 gtggtcgaat taatgggtcg tatcgagcct gcaaagacct ttatctcgcg tgctctatca
    22741 gccggaaagc ctgttgtgac tgctaataag gatttgatag ccttgtacgg aggagagctc
    22801 tcgactttgg cagctaagca tcaggtagct ttgtactacg aggctgctgt tgctggtggt
    22861 attccaatac taagagcttt ggctgattcc tttgcctcag ataagctgac gcgtctgctc
    22921 ggtgtgctca atggaacaac taatttcatg ttaaccaaga tgattgatga gggctggacc
    22981 tatgaaaggg ccctgcaaaa agcgcaggag ctgggctatg ctgaaagtga tccgactaat
    23041 gatgtgaaag ggatcgatgc agcttacaag gttgctattc ttagtcagtt tgcttttgga
    23101 atgaccattg actttgaggc tattagctat tcagggattg ataaggttcg agtagaagat
    23161 gtgacagtag cgcagaagct gggctatgtg atcaaattag ttggtctact tgaagagacg
    23221 gcttctgggc ttaacgcaga ggtatcccca gtctttttac caaagacaca cccgttggct
    23281 gctgtagacg gtgtgatgaa tgctgtttat atcgagtcaa ttggggttgg gcaggctatg
    23341 ttttatggtc caggtgccgg tcaaatgcca acagctacag ctgttgtggc agatatgatt
    23401 cagactgcct gcaccttacg tgaccataca gtctcagtct ttaatcgttt tgctacaaaa
    23461 actagactag ctaagtctga ggatattatg agtccctatt actttgctat tcaagcaact
    23521 aataagtttg gtcagctact agagctaaca aggctatgtg atgtttgtgg cattagagtt
    23581 gagcagctgt tatcagatga gatagatagt gacaggttag actttgtgat gattactcat
    23641 gagatgagca aaaaggagct tgcttgcttt acagcgctac tacaggatca tcaggatttc
    23701 cgtatgttaa gtacatttaa gattttagga gattgacatg aagatacgcg tacctgcaac
    23761 ctcggctaat ttgggacctg gatttgactc aatggggatt gctgtttcaa aatacctaga
    23821 agttgacatt ttagaagaac gtgaccaatg gtttattgag catgatttgg gtgatattcc
    23881 aaatgatgat agcaacttac ttatccaaac agcccttagg ctagcaccaa atattccagc
    23941 acatcgtcta aagatgacgt ctgatattcc attggcacgt ggcttgggat cgtcctcctc
    24001 ggtgattgtc gctggtattg aattagctaa tcagctaggg catttaaacc taacagacga
    24061 ccgtaaattg gccatagcaa ctcgtattga ggggcaccct gataatgtag ctccagcgat
    24121 ttttggtcaa ttggtaattg cttcacagat tggtaaggac gtggattaca tcattgcgcc
    24181 ttttcctgac ctttctttgg tttgttttat tcctgattat gagctgaaaa cctctgattc
    24241 cagagatgta ttgcccaagc agctatcgta taagcaggca gtggctgctt cctcagttgc
    24301 taatcttgct atagctgcgc tattgaccgg taatttgaaa aaggccggtc gggcgattga
    24361 aaatgaccaa ttccacgaaa tctaccggca aagattagtc agagagttcc agccgattaa
    24421 gcgagctgca gcagctaatg gtgcttatgc aacctactta tccggtgcag ggcctgctat
    24481 tatggttatg tgtcccaata agaaaaaaat ggcgatttat gaggccatcg agcagctagg
    24541 tctaattggt cagttggtgt ctctagagct ggatcgtcag gggctgtgtc ttgtctagac
    24601 tggcaaggta ctggtatgct tgcctagtag gcttattgtt gatatcagat ggacttaaag
    24661 cttagtcatt caaatacatc aaaaaagtga ggcttgatcg ttttatcggc tttcactttt
    24721 ttcttgatat gttatactag agtagacttt gtgaggtgtg tgatgaatta tcaagaaaca
    24781 ttagactgga ttcatggtca ggaaagattt gggatcaagc caggtgtaaa acgcatgcgt
    24841 tgggtgcttg agcagctagg taatcctcaa gataggatta gaggaatcca tgtggtcggc
    24901 acaaatggta agggatcgac ggtcaatgac ctacagcata tttttactag agcaggctat
    24961 gaggttggaa cctttacctc gccttatatc atggatttta aggaacgtat ctgtctcaat
    25021 ggtgagatga tctcagagac tgaccttgtt aaggctgcta attgtattcg tccactaacg
    25081 gatcgcctta tcagtgagac aagtttgggt cctgcaacag tctttgagct gatcactctg
    25141 atcatgtttc tttattttgg tgagagtcac ccggttgata ttgctattat cgaggcagga
    25201 ttaggggggc tttatgactc cactaatgtg tttcaggcga tggctgtggt ttgcccgtct
    25261 attggtcttg atcatcaagc tattttaggt gatacctatg ctgacattgc ctatcaaaaa
    25321 gccggtgtgc taaagggtgg tgaagacctt atttttgcca ttgataacaa agaggccaga
    25381 caggtttttc taaaaaaagc agagcagctt ggcgtgccta tttgggaatg gcgtcgacag
    25441 ttcaacatgc tacagggtga aggtggttat caatttaaca gtcagcttgg tcagctgtct
    25501 catctagtgc ttgcaatgcc tggtcagcat caggtagcca atgcaggcct agccactatg
    25561 acaagcttga tattacagga tcggtaccca aaggtaactg agtctgttat tagagaggct
    25621 ctggcaagca gcttttggtt gggacgaaca gaattgttgg cacccaacct gatgattgat
    25681 ggtgctcata ataatgaaag cattgccgcc ctgattgatg tgatatcatc agactatcag
    25741 gataagcaga ttcatattct atttggtgcc attgatacca agcctgtctc agatatgctg
    25801 cagagtctgg agcgtcttgg agatgtgcaa gtaacaagct ttcactatcc caatgcctat
    25861 cctttggagg cttatccaga taggctaaca aaagtagcag attttagagc atttttagac
    25921 cggcttgagc aagcagctgc tgatgatttt ttcctgatta caggctctct ttacttcatc
    25981 tcagaggtca ggcagtattg gaaaaaggta ttaagcaagt aatgctttct cacatcaact
    26041 catcaaacaa gattaatcaa ctaaaaaggg gaaaaccatt gccaatcaat caaaaaaaag
    26101 cagaagccgc tatctatcaa ttattagaag ctatcggtga ggatccaaac cgagaagggc
    26161 tacgagatac cccaaagcgt gttgccaaga tgtatctaga aatgctctca gggctggaac
    26221 aggacgctaa ggatgaattt acagctgttt ttacagagca tcacgacgat ttggtgattg
    26281 ttaaggatat tagcttttat tccatgtgtg agcaccatct ggtgccattt tatggtaagg
    26341 cgcatattgc ttatttgcct agtgatgggc gtgtgacagg cttgagtaag ctggcaaggg
    26401 cagttgaggt gacgagcaaa agacctcagc tgcaggagcg tttgacagct cagattgcta
    26461 atgctcttgt tgatgccttg cagcccaaag gggtttttgt tatggtagaa gcagagcata
    26521 tgtgcatgac catgcgaggt gtcaaaaagc caggcagtaa gaccattacg acaactgcta
    26581 gagggattta caaggatagt agagacgaca ggcgtgaggt tatgcaatta atcatggagg
    26641 gctagggtat ttatgactat tggacattat tcagccgctg gtgaggcagc tattatgggg
    26701 attttaaatg tgactccgga ttcgttttca gatggtggct cctatactag tgttaatcag
    26761 gccttggcac aggccgaaaa aatgctgtca gaaggagcga ctgtcattga tattggaggc
    26821 gagtcaacac gaccgggctg ccaatttgtg ccggcagaag aagagattgc acgcgttgtt
    26881 ccaatcataa aggccattaa aaaacggtat gatgtcctta ttagcattga tacctacaag
    26941 acagaaactg ctagagcggc ccttgaagca ggagcagata tgctcaatga tgtctgggca
    27001 ggactatatg acggtcaaat gctaagtcta gccgccgaat acgacgttcc cattatatta
    27061 atgcataatc aaaccaaaga ggcttatgct gatgttacaa aagaggtttg cagcttttta
    27121 caggctagag cagctgcagc cctcaaagca ggtgtcaaaa aagaacatat ctggcttgat
    27181 ccaggatttg gctttgctaa aaatgttgag caaaatatag ccttattaaa agggctaaat
    27241 gaggtttgcc agttgggcta tcctgttctt tttgggattt ccagaaagcg tgttgtagac
    27301 gccctacttg gtggcggcac taaagccaag gatcgtgacg gggctactgc cgccctatca
    27361 gcctacgcta ttaataaggg gtgtcaaatg gtgcgcgtgc ataatgtcgg tgctaacagg
    27421 gatattgtct ctgtattgag tcaattaagg tgagaaatga tggataaaat cagattagag
    27481 gcttgtcgct tttatggtta tcatggtgcc tttaaggagg agcaggtctt aggtcaaatt
    27541 tttgtagtgg atttagaatt atcagttgac ttgatggctg cctctctttc agactgccta
    27601 gaggatactg ttcattatgg tttagttttt gaaacagtcc gtcaaattgt tgaggaaaag
    27661 acctttacgc ttatcgaacg tttggctggt gccatttgtc aagagctatt tgcccagttt
    27721 ttgcctatta aagcgattaa aatcgctatt aaaaaagaaa atccaccgat tgcaggccat
    27781 tatcaagctg tcggtattga attggagaga aagagatgac acttgtttat ttaggcttgg
    27841 gaactaatat gggagatagg gcaggctacc tacaggcagc agttaatgcc ctatctaagc
    27901 tgccagagac tgagttactg agacaatcct ctatctatca aacagcagcc tggggaaaaa
    27961 cagatcaaaa tgcctttttg aatatggctt gccagctaga tactaggctg acatcagaag
    28021 ctcttttggc agctacgcag gctatcgagc aggctctggg acgagttcgt catgaaaaat
    28081 ggggcccaag gacaattgat attgacctct tgctgtttgg tgatgagccg tatcaatcag
    28141 agaccttggt tattcctcac ccttacatga cacaaagagc ctttgttttg attcctttat
    28201 tagagattgc acccgatgtg accttacctg gtagccagaa aagcctgagg tcttaccttg
    28261 atgctttaga gcaatcagat gtagccttgt ggtcacatga gtattcaaat aagttttctt
    28321 aaactgtcgt tatttttact aaaatttgat ataatagtgc tactctttgc tgattttttg
    28381 tcttatatta agaaatgatt gaagaaagaa gaagattatg atagctgaac ttgaaggcat
    28441 tgatattcga gagaatgaag ccttaaaaca ttacacctat acccaagtag gcggtccagc
    28501 agatttcttg gcttttccta gaaatcatta cgaactatcc cgtattgttg attatgccaa
    28561 tcataatcat attccttgga tggtccttgg aaatgccagt aatctcattg ttcgagacgg
    28621 tggtattcgt ggctttgtta tcatgtttga taagctcaac gccgtccgcc ttaatggtta
    28681 taccttggag gcagaggcag gcgctaacct cattgaaaca acaaaagttg ccaaatttca
    28741 tagcttaaca ggctttgaat ttgcttgtgg cattcctgga agcatagggg gtgctgtttt
    28801 tatgaatgca ggtgcttatg gtggagagat tgctcatatt tttttgtcgg ccaaggtctt
    28861 gacaccagaa gggaaaataa aaaagatctc agccagagag atggcctttg gctatcgtca
    28921 ctctgtcatt caagaaactg gtgatattgt gatttcagcc aagtttgctt taaaaccggg
    28981 taatcatgac agtatttgtc aggagatgaa tcgcctcaac caccttcgaa agctcaagca
    29041 gcccttagaa tttccctctt gtgggtccgt ttttaagcgt cctcctgggc attttgcagg
    29101 gcaattgatt atggacgcta acctaaaagg gcatcgtgtt ggcggtgttg aggtctctaa
    29161 aaagcatgca ggctttatga ttaatgttgc tgatggctct gccaaggatt atgaggactt
    29221 aattgctcat gtcattagga cagttgagca ggcatctggc gttaggcttg agccggaggt
    29281 tcgtattatt ggtgaaagcc tttaatgatt gtgttatcaa aaaagaaaaa ttgtggagga
    29341 tttatgacaa ttgactaagc caattatcac atttgacaat gtctcaaaga catttgagga
    29401 cagcgggaca caggtcctaa agaacattaa ttttgagctt gaggagggaa aattttacac
    29461 cctgcttggt gcctcaggat ctgggaaatc aaccatttta aatattatgg ctgggctgct
    29521 tgatgcgacc agtggtgata tttatttaga tggtgagcgt atcaatgatt tgccgaccaa
    29581 taagcgtgat attcacactg tttttcagaa ttatgctttg tttcctcata tgacggtttt
    29641 tgagaacgtt gcctttgctt taaagctgaa aaaggttgac aaacaggaga tagcaagacg
    29701 tgtcaaggaa accttaaaaa tggttcagct ggagggctac gaaaagcgat ccattcaaaa
    29761 gctttccggt ggtcagcgtc agcgtgtagc gattgctcgt gcgattatca atcagcctcg
    29821 tcttgtccta ttagatgagc cactttctgc ccttgatttg aaattgagaa cagaaatgca
    29881 gtatgagctg cgtgagctgc agcagcgact gggcattacc tttgtttttg ttacccatga
    29941 tcaggaagaa gcactagcga tgagtgattg gatttttgtc atgaatgatg gtgaaattgt
    30001 gcaatcaggc acacctgtag atatttacga tgagccgatt aatcattttg tagctagctt
    30061 tattggtgaa tcaaacatca tcaatggtac gatgattaaa gactatctgg tttcctttaa
    30121 cgggaaagaa tttgagtcag ttgatggtgg tatgcgaccc aatgagccag ttgaggtggt
    30181 tattcgaccg gaggatttac aaatcaccct gccagaggaa ggaaagcttc aggtaaaggt
    30241 agatacacag ctctttcgtg gtgttcacta tgaaatcatt gcctatgatg atttaggcaa
    30301 cgaatggatg attcactcaa cccgcaaggc cattgaagga gaagtgattg gtttagattt
    30361 cacaccagag gatattcata ttatgcgcct caatgaaaca gaagaagaat ttgatgctcg
    30421 tatcgaagaa tacgttgaaa tcgatgagca tgcggatggc ttaatcaatg ctattgagga
    30481 ggagcgcaat gaagaaaacc tctagcctct ttgcagttcc ctatttttta tggattgtcc
    30541 tctttgttat ggcaccggtt gcccttttgc tttatcaatc cttttttgac atcgaaggac
    30601 gattgacact agccaattac gagacttttt ttagctcatg gacttacctg agaatgggct
    30661 taaactctat cttatatgct ggtatcgtta ccttggtgac ctttttgatt tcatatccca
    30721 cagctttatt gttaacgcgt ttaaagcaca agcagctgtg gttaatgctt attattttac
    30781 caacctgggt caatctgctc ctcaaggctt atgcttttat ggggattttt gggcagcagg
    30841 gtggtatcaa tagcttttta acctttatgg gcttaggacc acagcaaatt ctgtttactg
    30901 atttttcgtt tatttttgtg gcctcttata ttgagctgcc ctttatgatt ttgcctattt
    30961 ttaatgcttt agatgatatt gatgataata ttatcaatgc cagtaaggac ctgggtgcca
    31021 atgactacca gaccttttca agggttatct ttcctttgtc gctaaacggt gttagagcag
    31081 gggttcagtc tgtttttatt cccagcttga gtctctttat gcttacgcgt ctcatcggtg
    31141 gaaatcgtgt gattacgctg gggacagcta ttgaacagca tttcctaaca acagaaaact
    31201 ggggcatggg ctcaaccata ggtgttgtcc taattatcgc gatgattgtg attatgtggc
    31261 taacaaagga gaaaagtaaa tgaaaaaatt tgccaatctt tacttagcgt gtgtttttat
    31321 tttgctctat attccaatct tttacttgat tgtttattct tttaacaagg gtggagacat
    31381 gaatggcttt tctggcttga cgctagagca ttataagacc atgtttgatg atagtcgctt
    31441 gatggcgatt ttattgcaga cctttgtgtt agcctttaca agtgccttgc ttgcaaccat
    31501 tatcgggacc tttggggcga tttttattca tcagagtaaa aagaagtacc aaaatgcgat
    31561 actgtctgca aataatgtgt tgatggtttc ccctgatgtg atgataggtg cctctttctt
    31621 gattctcttt acgtccttga aatttcaatt aggaatcctc tcggttttga tgagtcatat
    31681 tgctttttcc attccgattg tggtcttaat ggtgcttcct cggttgaagg aaatgaatca
    31741 agatatgatt aatgcagctt atgatctagg agcaaatcac tttcaaatgc taaaggaggt
    31801 tatgcttcct tatctgacac cgggcattat cgcaggctac tttatggcct ttacttattc
    31861 cttagatgat tttgcggtga ccttttttct aacaggaaat ggctttacaa ccctgtctgt
    31921 tgagatctat tcgcgtgctc gaaggggtat ttcattagat atcaatgcct tatcaacgat
    31981 tgtctttttg ttctcaattc tattagtcat tggctattat tacatttcac aggacaagga
    32041 ggaaaagcat gcgtaagcta tactcttttt tagcgggaat tatcggggtt atcttgctgc
    32101 ttgcgaccct gtcctttatt ttgcagaaaa aaacgagctc tgctagtcaa tctgataagc
    32161 tggtgattta taactggggt gattacattg atcccgcttt gctgaaaaaa ttcactaagg
    32221 aaaccggtat cgaggttcag tatgagacct ttgattccaa tgaagccatg tacaccaaga
    32281 tcaaacaggg tggaacgacc tatgacattg ctgttccgag tgattacacg attgacaaga
    32341 tgattaagga aaagcttctt gttaagctag ataagtccaa gcttgttggt ctagataaca
    32401 ttggtcagga gtttttagga aaaagctttg atccgcacaa tgattattcc attccttatt
    32461 tttggggaac ggtaggcatt gtctataatg accagctggt ggataaggct cctatgcatt
    32521 gggaggattt atggcggcca gaataccaaa atagtatcat gctagttgat ggtgctcgtg
    32581 agattttagg tgttggattg accacatttg gctatagcgt taactcaaag cacctaaagc
    32641 agcttgaagc agctgaaaaa aaactacagg ccttaacccc taatgtaaaa gcaatcgtcg
    32701 ctgacgagat gaaggggtat atgattcagg gtgacgctgc tattggtgtt accttctcag
    32761 gagaggctag cgaaatgctg gacaataacg accatctaca ctatgttgta ccatcagagg
    32821 gctcaaacct ttggtttgat aatctggtgc ttcccaaaac aatgaagcat gaaaatgaag
    32881 cctatgcctt tatcaacttt atcatgaagc cggaaaatgc agcacaaaat gctgaatata
    32941 tcggctatgc cactcccaat acaaaagcga aggctttatt gccagatgat attaaaaatg
    33001 acccagcctt ttacccaact gacgagaccg taaagaaatt agaggtttat gataatttag
    33061 gctctaaatg gcttggtatt tacaacgacc tttacctaca atttaagatg tatcgaaaat
    33121 aggtcatgca agattgaagg agctattcat tggaaagctt cttcagtctt ttttagcttg
    33181 gtctggtctc aataatctca tgagattaaa aagaactaga atcttgcttt cgtctttgat
    33241 acaatagtag tggtttatta aaatgaaaga gatgacaaaa tggaaaatca taaaaacgag
    33301 tttacctttt ccaaacattc aatcatagcc tacgtttggc gtggcatttt agtcgggata
    33361 attgctggag ctattgtcag tttgtttcgc ttattgattg agatggttag tgaggctgtt
    33421 gttggctatt atcaccaagc tcacagcaat cgcatgctcc ttgttccgat agcaggcttt
    33481 agcttattag ctgttttttt agttggtctt ttggtcaagt ctgacgccaa cattaaaggc
    33541 tctggtattc cacacgtcga aggggagcta aagggcttga tgtcacccaa ttggtggagt
    33601 gtgctttgga aaaaatacct tggtggaaca attgccattt ctatgggctt aatgcttgga
    33661 agagaaggcc cttctataca attaggggct atgtcagcta aaggcttagc taagtacctg
    33721 aaatctagtc gtctagaaaa acgtgtcttg atcgctagtg gagcagctgc tggcttatca
    33781 gctgctttta atgcgcctat tgcaggactg ctttttgttg ttgaggagat ttaccaccat
    33841 ttttcaagat tagtgtggat cactgccttg gttgcaagcc ttgttgcgaa ctttatttcg
    33901 ttgaatattt ttggccttag acctgttttg gccatgccta aggccatgcc ctttcttgcc
    33961 ttacatcaat attggctgct cttaatctta ggccttgtgc ttggctgtct gggctttctt
    34021 tatgaagagg tcattttaca ttttcatagg gtttatgatt ttcttggaaa gagcttgcgc
    34081 ctagcgccgc attttcatgg gctgattgtt gttgctatta tcctgctgat tggctattat
    34141 ttgccacagc tattgggcgg aggtcatggt ttgattatgt ccttgtcaga gcaaaagcta
    34201 ccactgttga ctgttcttgc ttacttcttt attcgatttt tagggagtat gtttagctat
    34261 ggcagtggcc tgcctggagg aatttttttg cctattctaa ccttaggtgc cttgtccgga
    34321 actatttttg gattgattct tcagcaaata ggactgttag atcgccagat gattcctctc
    34381 tttttagtat tgggaatggc aggctacttt gctgctgtat caaaggcacc cttgacagga
    34441 atgatcttag tgactgaaat ggtaggggat ctgaagccct taatggccat tgctgttgtg
    34501 accttcgtgg cctacttggt gatggatttg ttaaatggtc agcctatcta tgaagcaatg
    34561 ctagagaaaa tggctatcaa acacccaaca gatctagtgg agccgaccct gatcgaatta
    34621 cctgtaagtg agaaaattgc aggcagatat gtccgagacc tgaagctacc taaaaacgtt
    34681 ttaattacaa cgcagctcca ccataagaaa tcacaggtcg tctcaggtga tacgctattg
    34741 atttcaggtg ctacgatctt tttggtggtc aatgaagctg atacaggctt tgttcgagag
    34801 gtcttgatgt agagcaaggt cggttaagca gtcagcagta gctgtgctac cgatcaaaga
    34861 agcagatcag tgctttttct catctgatga aaggtattga tttgcttttt ttgtgttatt
    34921 aaacctttgt tagcaagagc catagcctta gcagtcgtat ctgatgaata cctgctgtct
    34981 ttttgttata cttaagtatc aatcaaagga gctttatatg ctagaagtta tttcaaaaga
    35041 gctgcgccat taccaaaaga ataagcttgc cgcctatcaa aaaaagaacc aaggcataga
    35101 agctggtgga attgtttttg ctggcgattc gttaatcgaa tttttcccgt tgaaaaaata
    35161 tttcaaacag gtctcaacca tttataatcg cggaattgca gggatagaca gtcagtggtt
    35221 gctagagcat attgacagtc atgtgaatga tctggagccc agtcatgtgt ttatcctgat
    35281 tggctgtaat gatattgggc ttggctttga tcaatcgcat atcgtatcga ccattgttga
    35341 tcttattagt cgtattcgca gtcagtctat ttatactagg attagccttc tgtccttatt
    35401 gccggtttct gaaaatcccg cctatcaggc gactgtcaag ctaaggacaa atagggctat
    35461 tgatgagatt aatcaagcat tagcaatgat accagcgatt gaatttattg atcttaacgc
    35521 ctgcttaaag gacgagactg gtggcttagc agctgcttat acggtagatg gcattcatct
    35581 taatgccctt ggctatgaac acttagctca agctattagt ccctatctat gaaaggtaaa
    35641 ggctggagct gctaatttgt aagggatctt taaaaaacaa gcactgatga atcatcattg
    35701 aaacccttca gagtgccgat aggctgcaca atcaaagaag cattaggttt gtctatgacg
    35761 cccttgtgtt aagctggctt ttaggtttat actgcgagaa aatcagtcat tgggctggga
    35821 gtctcaaagc ttagctgtgg taattaaatg cgagctcctg ctagcttgtg ctgatcaagc
    35881 agtatagcaa ggagggactg aacttttagt ctcagataat attagacttt ttatcctata
    35941 ttaaacgatt tagtgtataa taaacaggaa ggagttaaaa tgaaatttga aaaaaaacaa
    36001 gtcttttatg ttgtgcttgc ctttgtgctt tgttatgcta ttcaagctaa ttgggataat
    36061 ggggctaata ttgtcacaac cgtttataag acaagcctgc cctttcttta tggagcagca
    36121 gtcgcctata ttgttaatat tgtcatgagt gcctatgaaa gagcttatac ttatacccta
    36181 aaaccctttc cttttgccat gaaggctaga agagggctct gtatgctttt ggcatatttt
    36241 acctttatca gcttgatcgt atggattatt tctattgtaa tccctgattt gattgcaagc
    36301 attagctcgt taacgcaatt tgatacaaga gctatcaagg aggtcatcag tgatttaggt
    36361 cacaataagc tgattgcacg tgccattaat tacattggtg gagatgctaa gctgacagaa
    36421 acaattacca attatagcca gcagctgctc aagcaattta taggtgttct aaccggtatt
    36481 ttgacatcgg ttacagcagt tgcctcagcc attatcaatg tggttatcag ctttgtcttt
    36541 tccctgtatg tgcttgctag caaggaagag ctttgtcagc aggcaactac cttaattgac
    36601 acctatactg gtaaatacgc aaaggccatt cattatttag tgggtttgct gcatagtcgt
    36661 tttcgtggct tctttgtgag tcagacgctt gaagcaatga ttttaggctc cttgactgcc
    36721 attggcatgt ttatcctgca attacccttt gcaggaacta ttggagtctt ggttgctttt
    36781 actgccttga tccctgttgt tggtgcttca atcggtgctg cgataggctt tgttttgatt
    36841 atgactcagt caatgtcgca ggcagtcgtc tttattgtct ttcttgttat actacagcaa
    36901 atcgagggga attttattta tcccagagtg gttggtgggt ctatcgggtt accagctatg
    36961 tgggtcttaa tggcaatcac cattggtgct gctctcaaag gcattgttgg tatgatcgtt
    37021 gcagtgccat tagcggcaac gctttatcaa gtggtaaagg atcacattca taaaaagcag
    37081 gccttacaaa atcgtcagtc cagctaatta acagcatcag atcaaggaaa acgtctatta
    37141 caagaccgat ttcttggtct tttatgctgt ctgattgact gcgtatggcc ttatttttat
    37201 gctgtggtaa tgaaaaaagc cgtcttattt atcgaatatc attagtggag gtaataagat
    37261 gtattccatc aaaactgatc ataaattaat gcctagagag cgtttgattc gactgggtcc
    37321 agaaaagcta agcaatcaag agcaactagc gatcctactt aggacaggta acaaggaaaa
    37381 gcatgtctta gagttgtctg cttatttatt gtcaagctta gatagtctag ctgacttgaa
    37441 gaaattttct ttacaagaac tacagcgctt atccgggata ggaaaggtca aggctattga
    37501 gattaaggcc atgctggagc tggcagaccg tattcagata gcgggacaag cagtagcaga
    37561 tcctgtctta tctagtgctc aggtggctga aaagatgatg attgaattag gagacaagca
    37621 gcaggagcat ttagtcgcta tttatctcga tagtcaaaat aaaatcattg aagaaaagac
    37681 gatatttata ggaaccgtca gaaaatcaat tgcagagcct agagaaattc tttattatgc
    37741 gtgtaaaaat atggcgacta gccttattgt tgttcacaat catccctcag gcctgaccaa
    37801 gccaagcgca aatgactatc acttcacaga aaaaataaaa cgatcatgtg attatttagg
    37861 acttatctgc ctagatcaca ttatcgttag taagtatgac tactatagct ttcgggaaaa
    37921 atcagattta ttttgagtta gaaactatgg ataaaccaat caaagagcct taggtcttct
    37981 tctctaatag cctgaagcag ctctgggtgc cactggacac cgagaaaggg aatatcagga
    38041 ttgcaggaga taacagcctc gatggtgcca tcgttaggat cccttgcaat cactcttaag
    38101 tcctctgcga cctgctttag gctctggtgg tgaaatgaat taatcagcgc tcttggacca
    38161 tagatagggt acaaaggtga agtcttttcg atcactatct cctgtgataa acagtcagag
    38221 gcagtctttt gccaatggcc ctcaatgtgc tggtttagac tgccacctag agcaacattt
    38281 attaactgca taccgcgaca aatccctaaa attggttttt tctgcgctag ggcttcttta
    38341 atgatggcta gctcaaagat gtcacgctgg ggtgaaaaat caccatcaag tgcagctctt
    38401 ttttcatgat aatatttagg atcaacatgc tgaccaccaa taagaatgat tttatcaacc
    38461 attgcgacat aggatttggc agccgcctca tccccaatcg gaagaagtaa gggtaggcca
    38521 ccagatcttg tcacagcctc gatgaagctt gttggagcat aggagcaagg caggttatct
    38581 agagccttgg tccccctttg gttagcagtt atcccaataa ttgttttaga cacgaccttc
    38641 tccattaatc aagatgattt tggttcataa agtatagcaa ggtttgcaac tcgctggtca
    38701 aatcaacaga ttggacgatc acaccttttg gaacctgtaa gtgaagtgga gcaaagctta
    38761 aaataccgcg aatgccagct tcaatcagtt gatctgcaac ctcttgagca tagatgcttg
    38821 ggactgttag aatagccgtt tcaatgcctg aattatccag gtgctcctta atggtagaaa
    38881 tgccataaat aggaatatca tcaggcgttt tggtgccgac cataggatta tcatcagtgt
    38941 caaatcccat aacaatctgc attttgtttc gatcgtggaa gcggtagtga agaagtgcac
    39001 gaccaatatt gccgcagcca actaaaatca catgcgttgt tgagtgatca tttagcaaat
    39061 ctgcaaaaaa attcattaat tttgtgacat catagccaaa tccacgtcgg cctaattcac
    39121 caaagtaaga aaaatcacgt cgaacagttg cagaatcaat tcccatagca tcagcaatct
    39181 gttttgagct tgccttttca acctgatcag cataaaagcg tttaaaaata cgataataga
    39241 gtgataagcg ttttgcagtc gcttttggaa tagatttatc aataaccact tttgtagctc
    39301 cttctattgt tattttaatg ttatctatca ccattgtagc agatagattg tgaaatatgc
    39361 aactatttga ccattctttt tgtgtttttc gttataaaat gacttgacag cacaagcatt
    39421 ggtatttttc aaacccagtc acctcgagta taaaaaagca gacaatgaag cacttgccct
    39481 ttaggtcagc tgcgatggct gggcttgtct tgttaaaggc aaatgtactg tcattgtctg
    39541 atatttctct gagattagaa gagctcttgt gtgcttagca ttctttttta atgaaaatat
    39601 cacgctcaac aaggctatcc attaaaaagt aaaacttgtc ctgtagtatg ctatgctctt
    39661 cagatttaaa aatgttcacc agtcttagac cggattggtc tgttatagct agcttaaagc
    39721 catctaaatc tttattaatc gtaattttta aagggaagcc ctcacccgaa ttagggactt
    39781 tttccagtag tcgtgttaac tgatagtgac caatcttggt ctgactaaag gttgtgtctc
    39841 ttagggtgta ttttttaatc tttgggctaa tcctgtagct gtatttgcag tctttaaggg
    39901 caatttcttt ttcaaatgcc atatgatcct cctaaaatat ttttgagctg ggttgctagt
    39961 gcgataacgt ctttttgagt attttgctct gaaaagctaa ctcgaatagc ttctgtgaga
    40021 cgatgggact gcttgccgaa ataagctgcc aaaacgtgac ttggctcaac agcaccagct
    40081 gtacaagcag agcctgacga cacagcaaag cctgctaaat caagctgagt cagtaataca
    40141 tgattttggt aaccaggaaa gccgatatta atgatatagg gaagatgaca ctcattatga
    40201 ttgagctgat aagaaatacc ttctaattca ctaagcaaga gctgtgatag ctctttagca
    40261 tgctggtaat gctgtggcag ccttgagaca gcctcatcta atgcttgggt catgccgacg
    40321 atattaatca ggctttcagt gccggctctt tgtttgtttt cttgattgcc gccatgtaag
    40381 aggggggcca actttaagcc tttattgtat aaaaaaccag tcccctttgg tccatgaaac
    40441 ttatgggcag aggcagagag caaatcaatc cccaaatctg ccggctgtat tgggaccttg
    40501 ccaatagctt ggacagcatc aacatgaaag acagcctgat gctgctttag catgctacca
    40561 acagcctgaa taggcagcaa atctcccgtt tcgttgttag caaacatcat gctgactaag
    40621 attgtatcct ctcttaaggc agcttggagc tgatttagat caatgattcc atttttagcc
    40681 tcaaggtagg tcacctcaaa gccaaatcgt tcttccagat aggccattgt gcttaacacg
    40741 gaatgatgct caatagcagt tgtaatcaag tgtttgcctt tttcctgatg agctaaggca
    40801 tagcccttga tagcagtatt gttactttca gtacctcctg aggtaaagat aatgtggttt
    40861 tctgcagctc ctaggcagtt ggcaatagct tttcggcact ctcttaattg tttgtttgcc
    40921 tgccgcccat aagcatgaat actagatggg ttaccaaaat catcagccat agcttcagtc
    40981 atcgccttga tagcagcctg actaagcgat gttgtagcag cattatcaaa ataaatcatg
    41041 attagttagt gctttcaggt ttgtaagaaa acagtggact tagtggtttt ctttcgtgaa
    41101 tgcgaatgat agcctctgca attaaatcac tggcactaag ataggttact gttttaggga
    41161 tacgattttt agtcttgaca gagtccgtga caatgatctc tttgattgga gcagtctcta
    41221 aaatatcagc tgcacctcct gcaaaaatcc catgactagc cactgcataa atgtcagttg
    41281 cgcctgcaca ttctaggatc ttagctgcct ctgcaaaggt ttttcctgtg ttgagaatgt
    41341 catcaatcaa gatagccttc ttgccagcaa catcaccaat cacatagcct tcttcgcgct
    41401 cagcatcgtc ttgtgcataa tcgataatgg caattggaga gttaagatac tctgctaagc
    41461 ttctagcacg cttgatacca gaatttttag ggctgacaat aaccgtatca ggtcctgaga
    41521 ggcccagtgg ataatagtgc tttgcaaaaa gaggcactgt aaataaatta tcaactggaa
    41581 tgtcaaaaaa gccttggacc tgaaccgcat gcaaatcaag ggttacaacg cgatcaatcc
    41641 ctgctttggt cagcatgttt gcgaccagct ttgctgtaat aggctcgcga gactttgcaa
    41701 cacgatcctg acgcgaataa ccaaaatatg gcaaaacaat attgactgta ttagcacttg
    41761 cacgcttaca agcatcaatc atgatgagca gctcccatag gttatcgttg acaggaaagc
    41821 ttgttgattg aatgatataa atatcatcac cacgaactgt ttcttcaatg ttaatcatga
    41881 tctcaccatc agaaaattga cgagatgaga cctttccaag cggaatacca gcagccttag
    41941 aaattttttc agcgattgcg agatttgaag tgagtgagaa cagcttgatt tgcttgtcag
    42001 catatcgttc agtcatgata aaattagctc cttacattac attaacgata gaataacagg
    42061 ttaacagtta ttcaagatta caaatagaca gtactatttt aacaaaaaaa cagaaaaatt
    42121 tcagtctttc tgttgatttt ctgtcctctc ctaggatttt ttaagggtct tgctaaagcg
    42181 agcgaccttg cttttggaat atttaaaggt gatctgatgc tgggctaaaa agtggtcaaa
    42241 atcaaccttt cctcttacag gatcagtcac ctctagctca agctcatagt ctttgatacc
    42301 agcatattga ttataatcca gcgctagctt gccaatagga gtatctgcct ctcgacgaat
    42361 ggtagtcagg tttccgaagg tttttatagc agataggtca acgtcaagag tgctgataat
    42421 atcaaggata gctgattttg gtagctgtcc tgtctgaatg atagcttttg cttgggtgtc
    42481 atcaagctct aaattgtact cgcgattacc aaccttttca gggactttta aggttaattc
    42541 agcaggagca gcaacaaagg tgcgaatgcg aagtgacatt ttatgagcct tgagatcaaa
    42601 atgatcagta tcaatgtaat aatttgtctg ggtaactggt gggacatgag tcatttgaga
    42661 gaggaggcga ttatattcgt cctttgtcag taaggtcttg tattcgattt ctaggttagt
    42721 catgcgaacg ttccttttaa ctatatttta tgctataata aattgttatc ttaattttat
    42781 attaatatcc gaggtttgac aagaaaggag agaaaggatg gctttagatt gggaagaatt
    42841 tttggatcct tatatacaaa cggttggcga attgaaaatt aagctgcgcg gtatccgaaa
    42901 gcagtttcgc aagcaaaacc gttattctcc tattgagttt gtgactggac gtgtcaagtc
    42961 ggttgagagc atcaaggaaa aaatggcctt gcgtggtgtc ttggaagaaa atatcgctca
    43021 agatattcaa gacatcgctg ggcttaggat tatggtgcag tttgtggacg atattgagga
    43081 cgttttgtcc ttgcttagac aaagacagga catgacaatt gtttatgagc gagactacat
    43141 tagaaacatg aaatctagtg gttatcgctc gtatcatgtt gtcgttgagt atcctgttga
    43201 taccattgag ggtcaaaaaa aagtattagc agaaattcaa atccgtactt tagcaatgaa
    43261 tttttgggca accattgagc attccttgaa ctacaagtac ggtggtgatt ttccagaaga
    43321 aataaaaaaa cgattagagg ttacagcaaa aattgctttg gagcttgatg aagaaatgcg
    43381 aaaaattcgt gaagacattc gtgaagcaca attgttattt gatcctgtaa cacgtcattt
    43441 gagtgatggt gtaggaaata gtgatgacac agatgaatta tacagataaa gtaaagcgcg
    43501 ttgctatcat tgcaaacggc aaatatcaga gtaagcgcct tgcctcaaag ctttttggcg
    43561 tctttaagga cgatccgagt ttttacctat ccaaaaaaaa tccggatatt gtgatttcaa
    43621 ttggcggaga tggcatgctt ctatcagcct ttcatatgta cgaaaaagaa ttagacaggg
    43681 tgcgatttgt aggcattcac actggacacc ttggttttta cactgattat cgtgattttg
    43741 aggttgatca attgatagcc aatcttagaa gagacaccgg tgagcaaatt tcttacccta
    43801 ttttaaaggt agttattacg cttgatgacg gtcgcctgtt taaggctagg gctctcaatg
    43861 aagcaactat taagcgtatc gagaaaacga tggttgcaga tattatcatt aacaatgtca
    43921 agtttgaaag ctttcgtggt gatggcatct ctgtatccac accaactgga agcacagcct
    43981 ataacaaatc cttaggtgga gctgtattgc acccaacgat tgaggccctt cagctaacag
    44041 aaatctcgag cctgaacaat cgtgtattta gaaccttggg gtcctcagtg attattccta
    44101 aaaaagataa aattgagctt gttccaaaaa gactaggcgt ttatactgtc tctgttgaca
    44161 ataaaaccta ccacttaaaa aatgtggtta aggtggaata ttttatcggc aatgaaaaga
    44221 ttcattttgt gtcctcacct agccacacca gcttttggga aagggttaag gacgctttta
    44281 ttggggatag tgaatcatga ggtttgaatt tgttgcaact aaaaaaacaa aggtaaagac
    44341 ccttttaaaa gagcacgatg tgtcaaaggg attgctcgct aagattaaat acaagggtgg
    44401 caatatatgg gtaaatggcg ttgcgcaaaa tgccatttat ttattggata ttggtgatgt
    44461 ggtggctatt gatattccaa atgaggagtc ctttgagcaa ttgacagcga tttcgcatga
    44521 ccttgatatt gtgtatgagg acgaacattt tctcattctc aacaagcctg ctggctacgc
    44581 tagcattcca agtgctatcc attctaatac tatagctaat tttatcaagg cttattatat
    44641 caagcaggac tatcccaata aacaggttca tattgtgacg cgcttagatc gggataccag
    44701 tggcttaatg ctctttgcca agcatggcta tgcccatgcc agattagata agcagctaca
    44761 gcaaagagct atcaataaac gctattatgc tcttgtttgt ggtcaggaga ggcttccaga
    44821 tcaaggtgag attatagctc ctattggccg tacggacgac agcattatca caagaactgt
    44881 cacgccaaag ggaaagtatg ctaagacaag ctacaaggtc attgcccgct atcctgaaaa
    44941 tgtctctcta gtggatatta cgctgcacac tggtcggacc catcaaatta gggtacattt
    45001 tgctcatctt ggttttccac ttttgggaga tgatctgtat ggtggtcgat tggaccttgg
    45061 catgactaga caggcgctgc attgtcacca tcttagcttt acgcacccat ttacagaaag
    45121 tagaagcgat catacaatat gcttgacaga tgactttgag agcgttatca tagatttaca
    45181 gaaaaaagat agaggttagt taatgagtat tcgtaattta tttggtggtt taagggaaaa
    45241 aattgtcggc aaaaacatga agattgtttt ccctgaggga aatgatgagc gtgttgtacg
    45301 tgcagcagca cgtctaaagt ttgaaggtct tgttgagcca attattcttg gtcaggcaga
    45361 tgatattcgc agcctgctaa cacagctagg ctttgctgag cagcactata caatcattaa
    45421 cccaaatgat tatgctgatt ttgagaaaat gaaagcagcc tttgtagagc ttcgtaaggt
    45481 caaggcaacg cttgaagatg ctgatagact gcttagagat gtcaattact ttggtgttat
    45541 gctggttaag ctaggcttag cagatggcat ggtttcaggg gctattcatt caacagctga
    45601 tacggtgcgt ccggcgcttc agattatcaa gacaaagcca ggcatttcta gaacatcagg
    45661 tgtctttttg atgaatcgcg aaaatacaga gcagcgttta gtgtttgctg attgtgccat
    45721 taatattgac ccaactgctc aggagctcgc agaaattgcg gtaaacacag cagatactgc
    45781 gaaaattttt gatattgatc ctaaggttgc catgcttagc ttttcaacaa tgggctctgc
    45841 taaagcccca caggttgaaa aggttcaaga ggccgtccgt attgctaagg aattgaggcc
    45901 agagcttgct ttagacggtg agcttcaatt tgacgcagcc tttgtaccaa gtacagcagc
    45961 gatcaaagcc cctgattcat cagtggcagg ccatgcgaat gtttttgtct tcccagattt
    46021 acagtctgga aatattggct ataagattgc tcagcgctta ggcatgtttg atgctatcgg
    46081 accaatcctg caaggattga acaagcctgt taatgattta tcacgtggct ctagtgcaga
    46141 ggatatttac aagctagcta ttattacagc agcgcaagcg cttgaaaatg agtctatcaa
    46201 ttaactgcta atagccatta agttcacaag gcttagctat agtagatgtt gcttaaaacg
    46261 agttggataa gccagctcgt tttttcagaa agtgaggaag gaaatgacaa agattgcatt
    46321 agtaacaggc gcctctgctg gctttggtaa agccattgca gagcagttaa tagcccaaaa
    46381 catcaaggtg atcggagcag cccgccgcat agaaaagcta agagagctag aaggtatttt
    46441 tggttctgag aggttttatc cgcttcaaat ggacgtttca gaaccaactg ccattgataa
    46501 agcacttgca gaattaccta aagaatggca ggccattgat attttagtta ataatgcagg
    46561 actagcctta ggacttgata aggcctatga ggctgatgtc gccaactggc taaccatgat
    46621 taatactaat attattgggc ttatctattt aacacgtcag gtattaccgc aaatggtaag
    46681 cagcaacaat ggcatgatca tcaatatcgg ctcaactgct ggcactattc cctatccggg
    46741 agctaatgtt tatggggctt caaaagcctt tgttaagcag ttttcgctta atttaagggc
    46801 agatttagca ggaacaaata tcagggtgac caatattgag cctggccttt gtgagggaac
    46861 agagttttct catgttcgct ttaagggtga ccatgagcgt gttaaagcac tttatgcagg
    46921 tgcacatgct attcagccaa gggatatcgc aaatactgtc tcatggatta ttgatcagcc
    46981 agagcatgtt aacattaacc gcgtggaaat gatgcctgtc tcacaaagct atggttctca
    47041 gcctgttagc cgtcatgact aagaattaca agagcagatg taaaaggatt gtcgaagtgc
    47101 aacccaaaaa gacttaaagc ctagctgttt tatagcctgg ctttaagtct ttttctctaa
    47161 tttttcttag aaatgatccg aaagagaagg tccagatgtg acatctgacc acccaacaat
    47221 ggcctgccct gtttcttcca aatagtgctg cagcataggc ttgaagtcca aaatcatgtc
    47281 atagacccca acaaattgct tggtatcatc gtacaaggct tgatattgct gcatataaat
    47341 atgatcctgt gaagcagtcg gaataagata cagcttactg ccagttgccg ccttgtgcaa
    47401 atcagtcaag atccaatcct caatgacatc atgcttatca gaagcaaaaa aattgccatt
    47461 aaagcgatga ttatcaaaga tgatctgccc ctgatgatca gcaattctag cctgaagggg
    47521 aagataggtt aaaaaatgtg gggctaaggc ttggtaaaat tgcatgaggt atttagcaag
    47581 tcttaaagtt tgctgactat cagtaaaggt atgatcacta acggtaaatc cttgctcttt
    47641 gtctgcctga ttaaaataaa gtacaggtag tgaggcttca aggttctgaa aggtaaaaat
    47701 ggcctgagcc tttttgagct gctcagtagt cagctgacgg acaatagtga tatgaaacag
    47761 atagctaaac tcttgtgata aggtggtaaa aaaagtcttt tgcagattat tcttatcatc
    47821 aaccagtgct aaggtataaa tcgttttagt cataaggcta tcatagcttt attttgttta
    47881 aatagcaatg aaacagcctt ttagtctaca gacttagttg atagcttaat aaaagaaagc
    47941 aatatgaaaa aatgattaaa gcaaactagt tgacttgtta gtttaaactt tttataataa
    48001 atcaaatgag aagataatat gaggcttagc ctaagctgct gagcttatct gataatcatt
    48061 cttcttagca ctgagataac cccctttatc gattaattgg agaatctatg atacgtttta
    48121 ataatgtttc caaaaccttt ggtcacacca aggtgctgca ggagcaaagt tttcaaatac
    48181 agaatcgcga attttttgtg ctggtcggtc caagcggctc tggcaaaaca aagctcttaa
    48241 aaatgatcaa ttgccttact gaaccaagct ctggcgaaat tctattaaac ggaaggccac
    48301 aaaaagagct agatttgcga gatatgcgct tatctattgg ctatgttctt cagcaaattg
    48361 ccctgtttcc aaaccttaca gttgctgaaa atatcgctat tattccagag atgaagaagt
    48421 ggtcagacaa agagattaga actaagacag aggaattgtt agataaggtt ggattgcctg
    48481 caagggatta tctaaatcgc tatcccagtg atttatccgg tggagagcag cagaggattg
    48541 gtattgttcg tgccatcatt tctcacccca aggtgctgtt aatggacgag ccgttttcag
    48601 ccttggatcc tatttcacgc aagtaattac aggacttgat gttaagtctt cacaaggagt
    48661 ttgatatgac aattgtcttt gttactcatg atattgatga ggctatcaag cttggagatc
    48721 gtgtggctgt tttaaatgaa gggcaaattg ttcaactgga tcgaccagat gcgatcatag
    48781 ctgcgcctgc taatgatttt gtagcaagtc tatttggagg tcgtgattat gcctagttta
    48841 ctgatgacct tttgggatcg ttttggtgat tgggcaaggg cattaggaga gcacttgcag
    48901 atttctcttc tttctttgct ggctgccttg ctgataggca ttccgcttgc agctctgttg
    48961 agtaaaagta agcgctggtc aaatatcatc ttgcagctga caggtgtttt tcaaaccatt
    49021 ccttccctag ccttgttggg actatttatc cctctaatgg gaatcggaac tgctccagct
    49081 gtaacagctt tggttattta tgccatattt cctattttac aaaatacgat tactggctta
    49141 aatgctattg atccaagtct tgtagaggcc ggaacagcct ttggaatgac caagtgggag
    49201 cgactgaaaa tatttgaaat tcctattgct atgccagtta ttatgtcagg tgttcggacc
    49261 tcagcagtga tgattattgg aacagccacc ctagcttctt tgatcggagc tggcggctta
    49321 gggaccttta tcctattagg aattgaccgt aataatgctc agctgattgt gattggtgct
    49381 gtgtcgtcag ccttgcttgc gatagtgttt aacagtcttt tgtgatacct tgagaaggcc
    49441 tcactgaggc gtattgcgat aagctttgct gcgaccttat tactgctctt aatttcctat
    49501 actccaatgt ttgtcaagcg gtttgttaat cagtcaaata ctctggtgat tgctggcaag
    49561 ctaggagtag agccggatat tttgatcaat atctataaag agctgattga agaccagtcc
    49621 aagcttaagg ttgaattgaa acctaatttt ggcaagacaa gctttttata cgaggcgatt
    49681 aaatcaggag atattgatat ttatccagaa tttacaggaa ccatcacctc tagcctatta
    49741 aagaaaaagc ctaagctttc taatgaccct aatcaggttt acttagctgc taaggagggg
    49801 attgctgagc aggatcagtt gacgctttta aagccctttg cctatcaaaa tacctatgca
    49861 gtggcgatgc ctgaaaaaat agctgacgaa tttaacattc aaagtatttc agatgtgaag
    49921 aaatatgaaa aacagctaaa ggctggtttt acactagaat ttaaggatag agaggacggc
    49981 tataagggca tacaggataa gtatgatcta catttatcag ttgcaacgat ggagccagct
    50041 cttaggtacc aagccattca gtcaggaaac attcagctga cagacgctta ttcaactgat
    50101 gctgagatcg tgaaatatca gcttcgagtc ttaaaggacg ataagcagct ctttccacct
    50161 tatcaaggag cgccattgat gaaggcttcc ttactaagaa agcaccctca tctcaaaacg
    50221 attctcaatc agttatcagg aaagattact gaagaggaga tgcaagcaat gaactatgag
    50281 gtgtccgtaa agggcagagc agctagcctt gtggcacatg actaccttgt aaaggccggt
    50341 cttattgcaa gaaccaaata agcaggcatg ctagtcttat tctggactgg catgctttat
    50401 ttatgtgatt tttagtctgt ctggctctgc aaggtgtgtg ccaaataacc gctcgtttga
    50461 tgtgtggtta ttgatttagt agctaaggat tggaatctta aaataaaatc cgaacgtttg
    50521 tctaaaaaaa gctttaaaaa ttgacaaaac ataaacgaaa ggataaaata aattaaggaa
    50581 aggtaacatt ttacctagcg atgcctcgga caagcttgag gtcataggaa ggtcatttta
    50641 tatagaagct tatgtcagct gcagatcagg gaagtccttg ctggattagt agctgaatgt
    50701 tgaaaaagga gagaaatgat gtttaatgac atgcctgtat ttgattatga ggatattcaa
    50761 ttaattccta acaaatgtat catcaatagt cgttcagaag cagatacgag tgtaagactt
    50821 ggtaattata cctttaagct acctgttatt cccgccaaca tgcaaaccat tattgacgaa
    50881 acaattgcag agcagttggc aagagatggt tatttctata ttatgcaccg ctttgatgag
    50941 gaggggcgca agccctttat ccagcgtatg catgagcaac agctcatcgc ctctatttcg
    51001 gttggtgtaa aggattatga atacgatttc gtctcttctt tgaaggagga cgcacctgag
    51061 tttatcacga ttgatattgc tcatggccat gctgatagtg tgatcaaaat gattaagcat
    51121 attaaggctg agctgcctga gacctttgtt atagctggaa atgtcggaac accagaggct
    51181 gttcgagagc tcgaaaatgc tggtgctgac gcaacaaagg tcgggattgg gcctggtaag
    51241 gtttgtatca caaaggttaa gacaggcttt ggaacagggg ggtggcaatt agctgctgta
    51301 cgttggtgtg ctaaggctgc tcgtaagccg attattgctg atggcggtat tcgtactcat
    51361 ggtgatattg ccaagtcgat tcgatttggg gcaacaatgg tgatgatcgg ttcactcttt
    51421 gcaggtcata ttgaaagccc aggcaagatg gtagaaatcg acggacagtc cttcaaggaa
    51481 tattatggct ctgcctctga atatcaaaaa ggggagcata aaaatgtcga aggcaagaag
    51541 attttgcttc caaccaaggg tcatctagct gatactttaa ccgaaatgaa gcaggattta
    51601 cagtcatcaa tctcatatgc tggaggcaga gatttggaga gcctgcgtcg tgtgaattat
    51661 gttatcgtga aaaattctat ttggaatggt gactctattt aaagccttgg ctaaagacct
    51721 agtctaaata aggataagca agctgattga tgctgagaat aagcacagcg tgtctatagg
    51781 acgcctgaat gtctagtagc cagtaaagct tttaggcttg ctgattggat aggtcattgt
    51841 gcctatgtgc agcagggctc tagggactta gataaaaagg agacatgatg aggttactgg
    51901 aggagcgtat cctagctgat ggaactgttt taggtgagac gattttgaag gtggatcaat
    51961 ttttaacaca tcaggttgac tatcgcttga tgaaggaaat cggtagagta tttgctgatc
    52021 aatatgctga tttgggcatt accaaggtgg tcaccattga agcctctggt atcgcaccag
    52081 cagtttatac cgcagaagct cttgaggttc cgatgatttt tgccaaaaag cacaaaaata
    52141 tcacgatgac agagggaatt ttaacagcag aggtttattc ctttaccaaa caagtgacaa
    52201 gtactgtttc tattgcagga ggactgctat caaaagaaga tagggttttg attattgatg
    52261 actttttggc taatggtcaa gcggcaaaag gcttgattga tatcattcat caagcagggg
    52321 ccaaagctgt tggcataggc attgtcattg aaaaatcttt tcaggctgga cggcaattgc
    52381 ttgaggattt gggagtagag gtcacttcat tggctcgtat taagcatttt gacaatggaa
    52441 tagtaagctt tttggaggct gatgcctgat gactgcttct tatctctcag cattaagctt
    52501 tttacttgta tagctatacc agctttattt cagtagctat tggctggtga taagggatat
    52561 tggtatggcg gtgcattacg gcgagccgtg ggcagttgcc cttgcggctt tacgatttag
    52621 tatagactat caagaattga ctgcttcctt tttatcgaga tgaatcatta gacagacaat
    52681 catgatttgg cgtgaaggct gctttcagta aacattacat catcaaaaat cagctaggta
    52741 ttcacttagc tgatttttag tgcttataat gtagccgaaa ggctcccttt aacccgtctg
    52801 agatagtaac ctgaccatct ttggtaatga taatgccttc cacctcaggc agcttattta
    52861 gctgacttag gacaaaggaa tgctctaagc caaaaagacg actactccat agctcaccat
    52921 caagtgagaa ttggctgaca atggttaggc tagccatatt ggtcttgata ggatagccgt
    52981 tgtgaggatc aagaaggtga tgataagttt tgtctttgat ttgtaattgt ctctcgccga
    53041 ttcctgaggt tactacagat ttattgttaa ccttaatcac gccgacatgc tgtcctcttt
    53101 tttgattggt ctgctggatc ccaacgtaaa acaagccatt atgtcgttgc ttgttggtgc
    53161 catgcacaag gacatttcca cctagattga taagagcagc agtgataccg tctttaataa
    53221 gaaatgccat gagcttatca gcaatatagc cctttgctag ggcacctaag tcgatagaca
    53281 tgcccttttc tttcaaaaaa atacttccaa ggctttgatc taa
//
LOCUS       DARYLJ010000009        50641 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYLJ010000009 DARYLJ010000000
VERSION     DARYLJ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50641
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            96..884
                     /locus_tag="TU746_000470"
     CDS             96..884
                     /locus_tag="TU746_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0890848.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
     gene            893..2062
                     /locus_tag="TU746_000471"
     CDS             893..2062
                     /locus_tag="TU746_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL0890849.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            2065..2268
                     /locus_tag="TU746_000472"
     CDS             2065..2268
                     /locus_tag="TU746_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890850.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2400..3833
                     /locus_tag="TU746_000473"
     CDS             2400..3833
                     /locus_tag="TU746_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0890851.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3863..5032)
                     /locus_tag="TU746_000474"
                     /pseudo
     CDS             complement(3863..5032)
                     /locus_tag="TU746_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            5088..5729
                     /locus_tag="TU746_000475"
     CDS             5088..5729
                     /locus_tag="TU746_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL0890852.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            5850..6776
                     /gene="cysK"
                     /locus_tag="TU746_000476"
     CDS             5850..6776
                     /gene="cysK"
                     /locus_tag="TU746_000476"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL0890853.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(7163..7525)
                     /locus_tag="TU746_000477"
     CDS             complement(7163..7525)
                     /locus_tag="TU746_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL0890854.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(7525..8925)
                     /locus_tag="TU746_000478"
     CDS             complement(7525..8925)
                     /locus_tag="TU746_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0890855.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(8958..9599)
                     /locus_tag="TU746_000479"
     CDS             complement(8958..9599)
                     /locus_tag="TU746_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0890856.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(9592..10596)
                     /locus_tag="TU746_000480"
     CDS             complement(9592..10596)
                     /locus_tag="TU746_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0890857.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(10593..11285)
                     /locus_tag="TU746_000481"
     CDS             complement(10593..11285)
                     /locus_tag="TU746_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL0890858.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYVIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(11418..13313)
                     /gene="pknB"
                     /locus_tag="TU746_000482"
     CDS             complement(11418..13313)
                     /gene="pknB"
                     /locus_tag="TU746_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL0890859.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(13310..14050)
                     /locus_tag="TU746_000483"
     CDS             complement(13310..14050)
                     /locus_tag="TU746_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL0890860.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(14088..15410)
                     /gene="rsmB"
                     /locus_tag="TU746_000484"
     CDS             complement(14088..15410)
                     /gene="rsmB"
                     /locus_tag="TU746_000484"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL0890861.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(15400..16335)
                     /locus_tag="TU746_000485"
     CDS             complement(15400..16335)
                     /locus_tag="TU746_000485"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL0890862.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(16402..18786)
                     /locus_tag="TU746_000486"
     CDS             complement(16402..18786)
                     /locus_tag="TU746_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL0890863.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(18850..19167)
                     /locus_tag="TU746_000487"
     CDS             complement(18850..19167)
                     /locus_tag="TU746_000487"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL0890864.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARIEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(19192..19818)
                     /gene="gmk"
                     /locus_tag="TU746_000488"
     CDS             complement(19192..19818)
                     /gene="gmk"
                     /locus_tag="TU746_000488"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL0890865.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(19980..21590)
                     /locus_tag="TU746_000489"
     CDS             complement(19980..21590)
                     /locus_tag="TU746_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL0890866.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            21747..22232
                     /locus_tag="TU746_000490"
     CDS             21747..22232
                     /locus_tag="TU746_000490"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL0890867.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(22377..23828)
                     /locus_tag="TU746_000491"
     CDS             complement(22377..23828)
                     /locus_tag="TU746_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890868.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPQVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(23842..24996)
                     /locus_tag="TU746_000492"
     CDS             complement(23842..24996)
                     /locus_tag="TU746_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL0890869.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(25060..25428)
                     /gene="rnpB"
                     /locus_tag="TU746_000493"
     ncRNA           complement(25060..25428)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TU746_000493"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(25441..25764)
                     /gene="gpsB"
                     /locus_tag="TU746_000494"
     CDS             complement(25441..25764)
                     /gene="gpsB"
                     /locus_tag="TU746_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL0890870.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(25886..26401)
                     /locus_tag="TU746_000495"
     CDS             complement(25886..26401)
                     /locus_tag="TU746_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL0890871.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            26477..27085
                     /gene="recU"
                     /locus_tag="TU746_000496"
     CDS             26477..27085
                     /gene="recU"
                     /locus_tag="TU746_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL0890872.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            27072..29237
                     /locus_tag="TU746_000497"
     CDS             27072..29237
                     /locus_tag="TU746_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0890873.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(29280..30614)
                     /gene="pepC"
                     /locus_tag="TU746_000498"
     CDS             complement(29280..30614)
                     /gene="pepC"
                     /locus_tag="TU746_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL0890874.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(31303..32127)
                     /gene="nadE"
                     /locus_tag="TU746_000499"
     CDS             complement(31303..32127)
                     /gene="nadE"
                     /locus_tag="TU746_000499"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL0890875.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(32124..33584)
                     /locus_tag="TU746_000500"
     CDS             complement(32124..33584)
                     /locus_tag="TU746_000500"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL0890876.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(33860..35254)
                     /locus_tag="TU746_000501"
     CDS             complement(33860..35254)
                     /locus_tag="TU746_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL0890877.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(35374..36291)
                     /gene="trxB"
                     /locus_tag="TU746_000502"
     CDS             complement(35374..36291)
                     /gene="trxB"
                     /locus_tag="TU746_000502"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL0890878.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(36351..36578)
                     /locus_tag="TU746_000503"
     CDS             complement(36351..36578)
                     /locus_tag="TU746_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL0890879.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(36688..37431)
                     /locus_tag="TU746_000504"
     CDS             complement(36688..37431)
                     /locus_tag="TU746_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0890880.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(37431..38234)
                     /locus_tag="TU746_000505"
     CDS             complement(37431..38234)
                     /locus_tag="TU746_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0890881.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(38611..39438)
                     /locus_tag="TU746_000506"
     CDS             complement(38611..39438)
                     /locus_tag="TU746_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0890882.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            39946..40401
                     /locus_tag="TU746_000507"
     CDS             39946..40401
                     /locus_tag="TU746_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890883.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            complement(41042..42385)
                     /locus_tag="TU746_000508"
     CDS             complement(41042..42385)
                     /locus_tag="TU746_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0890884.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(42468..43475)
                     /locus_tag="TU746_000509"
     CDS             complement(42468..43475)
                     /locus_tag="TU746_000509"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL0890885.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            complement(43477..45732)
                     /locus_tag="TU746_000510"
     CDS             complement(43477..45732)
                     /locus_tag="TU746_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0890886.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            complement(45736..46059)
                     /gene="ftsL"
                     /locus_tag="TU746_000511"
     CDS             complement(45736..46059)
                     /gene="ftsL"
                     /locus_tag="TU746_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL0890887.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            complement(46063..47013)
                     /gene="rsmH"
                     /locus_tag="TU746_000512"
     CDS             complement(46063..47013)
                     /gene="rsmH"
                     /locus_tag="TU746_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL0890888.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            complement(47116..47532)
                     /locus_tag="TU746_000513"
     CDS             complement(47116..47532)
                     /locus_tag="TU746_000513"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890889.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            complement(47552..48799)
                     /locus_tag="TU746_000514"
     CDS             complement(47552..48799)
                     /locus_tag="TU746_000514"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL0890890.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            complement(48799..49617)
                     /gene="proB"
                     /locus_tag="TU746_000515"
     CDS             complement(48799..49617)
                     /gene="proB"
                     /locus_tag="TU746_000515"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL0890891.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            50218..>50641
                     /locus_tag="TU746_000516"
     CDS             50218..>50641
                     /locus_tag="TU746_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890892.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
BASE COUNT        14968 a        11579 c         9677 g        14417 t
ORIGIN      
        1 atttacgaaa aaaatcgtat ttattttaaa aatactattt acaaatacga tttaaagcga
       61 tatcatatga gtataaaaat cgaaaggaaa ataatatggc aagaggaaga ggtagattaa
      121 cacctcaaga aatagaggcg ttaggattct tttcgagcaa attcaatgat ctgctcaacg
      181 aaacaaatac aaagcaagtt gaactctcaa aggctacagg aataccacca agtacgctca
      241 caggttacgt aaaagggaca tctttaccta ttcccggtaa tgtccaaaaa atagccgatt
      301 attttgggtt aatgaaatca gatatagatc caagatttgc acctcgtaag aaaaatcacg
      361 aacttaagat tcctacttct ccacttgtca aaaaaataac cacaactgtc gtggaattaa
      421 atgttcctcg taagcaaaaa gttttagact ttgcaacaga tcaattaaaa gaacaaaaaa
      481 ataaaatgac ttctatggag aaaaaactct atgagtataa agtttacgag aagctttcag
      541 ctgggacagg ttatggatat tttggtgacg ggaactatga tactgtcttt tacgaagaag
      601 aattagacta cgatttcgct tcttgggttt tcggcgattc tatggagccc acttatttaa
      661 atggtgaagt tgtgcttata aagcaaactg gctttgatta cgaaggcggt gtctatgctg
      721 ttgaatggga cggacaaacc tatattaaga aagtttatag ggaaaaagat ggattaagat
      781 tagtttcttt aaataaaaaa tacaaggata agtttgctcc ttttagcgaa gatccgcgta
      841 taatcggcaa aatcgtcggc aactttatgc ccaaagaata ttgaggtgtg ttatgggatt
      901 gtttaatttc ggaaaaataa aagatgtggc tctagaaaag aaattacaaa agttacaaca
      961 aaaaattgaa aatgaaaaag aaaaattgag ggaaattaaa gaagaaattg cattagccaa
     1021 tgatacatta gaccttcaag aatatggttt ttttgaacgc cagtataaat tttcccatag
     1081 tactaaatat aaagatgctt tagatacgtt acgaatgaaa caaaaaacac tcataaaaaa
     1141 tggtgaagct acaagcataa tttcccccat gactctagat ggtagtgcag caaaaggtaa
     1201 agcaatgcag aaccaactta ggaaagctgc aatccgcggc tttaatggtg aagccgatgc
     1261 cttactagtt aaagtgtctg tcgtaaatgt agataaaaaa gtgcaaactc ttcagaaggc
     1321 tttcgaacaa ttaaataaaa tgtatgaaag gaacttgatc caacttacct ttaaatattt
     1381 agatttaaaa gcacaagaat tgagattagc tgctgaatac gaattgcaaa aacaagaaga
     1441 aaaagaaatt ctaagagaac agcgtgcaag agaaagagaa gataaaaaac ttcaagctga
     1501 gattactgct aaaagaaaac aacttgaaaa agacaggaag cactttttac aaatggtcaa
     1561 gaacgtcgaa gtgatgcttg ctaacgcttc tccgaaagaa caagagaaat tacaattgca
     1621 attaattgaa taccaaaaca agctctcaga acttgataag attgaagaag acattgatta
     1681 tagagaagga catgcaacag ctggatatgt ctatgttatt tctaatatag gtgcttttgg
     1741 agaagatgtt tataaaattg gagtaacaag acgtttagac ccaatggatc gtattcgcga
     1801 attggggagt gcatcggtgc cttttacttt tgatgttcat gcgcttatct ttagtgagga
     1861 agcttttgct ttagagtctg agttacataa taaatttgaa gcgtataaag taaataaaat
     1921 aaacagtcga aaagagtact ttagagttcc gtttgctaaa atcaaagaag ttctagaaaa
     1981 tcataaagaa ttagctattg agattaccga agaagctgaa gcgtttgaat accgtcaaag
     2041 tatcttgaaa aatgggggtt aaatatgaaa tggttattcc taattttatt tataggctgc
     2101 ggtgctaatg ctgtaaacct ttctaaaaaa gttaattccg atgatgaagt tgacgaaaac
     2161 aacagtcacc ttatatcaca ttcaaatgaa gagattcctt ggaataaaaa agaacagctt
     2221 tattggggca ctgcttccat tgtattttta gtgcttttta taatctaaac acaataataa
     2281 aaagcctcac gctcaacttt ggtcgatgcg agcgtgaggc gaacgtgtat agtaaaaacc
     2341 tgctttgcag taggtctctt tactataccc attttaacat aaaaatgagg tgaaaaacaa
     2401 tgattacaac aagaaaagtc gctatttatg ttagagtcag tacaacaaat caggcagagg
     2461 agggctattc aatacaaggt cagatagaca gtttgatcaa atactgcgaa gctatgggtt
     2521 ggattatata tgaggagtac actgatgctg gcttttcagg aggtaagata gaccgtcccg
     2581 ccatgtctaa actaattaca gacgcaaagc ataaacgatt tgatacaatc ttagtttata
     2641 agctagacag actctcccga agtgtcagag atactcttta cttagttaaa gatgttttta
     2701 accaaaacaa tatccatttt gtcagtctgc aagaaaatat tgacacttct tcggctatgg
     2761 gtaatctatt cctcacattg ctatctgcaa ttgccgaatt cgaacgagaa cagataacag
     2821 agagaatgac aatgggaaaa atcggaagag caaaatccgg aaaaactatg gcctggactt
     2881 ataccccttt tggctatgat tacaacaaag aaaaaggcga attgatttta gatcctgcaa
     2941 aagcgcctat agttaaaatg atatatacag attatctcaa aggtatgtct attcaaaaaa
     3001 tagtggataa acttaataag atggactaca acggtaagga ttgcacttgg tttccacatg
     3061 gtgttaagca tctattagat aatcctgtct attatggtat gacaaggtat aataataaat
     3121 tattccccgg aaatcatcaa ccaattatta caaaagagct atttgataaa acccaaagag
     3181 aaaggcaacg cagaagatta ggaatcgaag aaaaccacta cacaatacct tttcaggcga
     3241 agtatatgct aagtaaattt ttaagatgtc gtcaatgtgg ctcaagaatg gggcttgagc
     3301 ttggcagacc aagaaaaaaa gaaggcaaaa gatccaaaaa atactattgc ctaaatagta
     3361 ggccaaaacg aacagctagt tgcgacacac cactttacga tgcagaaacc ttggaggatt
     3421 atgtgttaca cgagatagcc aaaatacaaa aagatccgtc aatagcgagc agacaaaaac
     3481 atattgagga tcacgaatta aaatacaagc gtgaaagaat tgaagctaat atcaataaaa
     3541 cagtgaatca actctctaag ctaaacaatc tttatcttaa cgatctgata actcttgaag
     3601 acctcaaaac tcagacaaac actcttatag ctaaaaaaag attgctagag aacgaactag
     3661 ataaaacttg tgataacgat gatgaacttg acagacaaga aaccattgct gactttctcg
     3721 ccttgcctga tgtatggacc atggactatg agggtcaaaa atatgctgtt gagctgcttg
     3781 ttcaacgtgt taaagttgat agagataata tagacattca ttggactttt taatgccaaa
     3841 aattacaaag ttttcaaccc ttgatttgaa taagactgct gcttgtgtaa aggcgatgat
     3901 tggctaataa gacaaagaca tctacggttg gaaaggtcac acctctttcc aaaatggttg
     3961 ttgatataag tatagtgatt tgtccttgtc tgaattgctc aatgatagcc attcgatttg
     4021 atgactgact ggaagcatga gcaatagttt ccttaggaaa atacttgtgg agcagctgac
     4081 agcattgctc agccagctca ataatcggaa aaaagattaa aagaggatag ccggttgccc
     4141 tttgtttttt gactagggtg atgaaccttc taggcaattt cccacgattg atagcctcta
     4201 aaagggagaa taatctttga tactttggaa caactaaggg cttgccatgg aatcttcttg
     4261 ccaacgtcaa tttgacaagc tctttttgct tgaccttgcg ctctaaatct cttgtagagg
     4321 ttgctgttag gtatactgtc actgcatctg cttttgcagc ctgatgagca gcatggttta
     4381 attgacgatt attgacaaag gggaaggcat ctacttcgtc aataatgagc agatcaaaag
     4441 catggtaaaa ggtcatcaat tgatgtgttg tggcaacgat aatggggctt ctatgataaa
     4501 cctctgactc agcatgcata aggcagactt gacaggaaaa gtcccgcgat agtcgttttt
     4561 caagctctat gcaaacatca actcgtggac tagcaatgca gacccagcca cccttattaa
     4621 caactgctgc aatagcttca tacatcatct ctgttttgcc agcaccagta accgcatgaa
     4681 ctaaggtgtc ttgcttgagc ttaacatggt tagtaagctg atgagagata gctgcctgat
     4741 atgtcgtgag ctgtccttgc cacctcagat aatgtccctt tggaaaagaa gccggtggaa
     4801 aatagagcaa ggggcgatca gattggtttc gaccaaaaac aagacaggct ctacagtagt
     4861 aagcaccgct aggcagctga tgagccttct caattaaact gctacagcgt tggcagtata
     4921 acgttccctt tttagtgatc atgctttgta agctgcaagc ccaggcagaa acagcctttg
     4981 ggcattgcct ttcgggtaaa agacgtccat agtaattttc gatattctcc ataccttatt
     5041 atccgaatta ttttgctaaa tatcagcatt ttttgtaaaa ttttcttatg gaagattata
     5101 aaactattat gactgatggg ctttttgagg aaagcatcaa aaaatctcgc tttatttgcc
     5161 aaatcaaacg cgtctacaca gaagaggagg ccagagcctt tattgctgac atcaaaaaaa
     5221 agcactataa ggccaatcat tcctgctctg ctatgattat cggagacaaa ggacaaacca
     5281 agcggtcaag cgatgatggt gagccatctg gtactgctgg tattcccatg ctatctgtct
     5341 tagaaaggca ggaattaacc aatcttgtag ctgttgtgac acgctatttt ggaggtgtta
     5401 aattaggagc tggagggctc attcgcgctt actccggcgt aactgcggca gctattcagg
     5461 ccttaaaggt cgttgaggta aaaaaacaaa ctggactagc aatcagcctc acctaccctc
     5521 aataccaaat ctatcctaat tttctggagc aagaagcatt gattgaaatg aataccgaat
     5581 tttctgatgt cgtcagaaca gctatttact ttgatcctga gcgcttggag agtatttcta
     5641 aggcattgat tgagcattat catggcaagg tttcctttga agagatcgaa tcgcaaagga
     5701 ttgaggtccc tgttttgcct gccaattagc atgaacagtg atagcgtctc tttatcacta
     5761 cgatagtaaa tggctatttt actttgtcga ttattagcta tatactttta tataagcatg
     5821 tattgataca aggataaaaa ggaggaccta tgtcaaagct atatcacaac attacagagt
     5881 tggttgggaa aacccctatt attaaattga gaaacaccag tccagaggag gctgccgata
     5941 tttatgtcaa gctagaagct tttaatccag gctcttcagt taaggatcgc atagcacttg
     6001 caatgattga agctgctgag aaagcaggca tgatcaagcc aggtgataca atcgttgagc
     6061 caaccagtgg caatacaggg attggcttat cctgggttgg ggctgcaaaa ggctaccgag
     6121 tgctcattgt aatgcctgag acaatgagta ttgaaagacg tcaaatcatt caagcttacg
     6181 gagcagagct cgttttaacc ccaggtagtg atgggatgaa aggtgcgatt gctaaagcag
     6241 aagagattgc cagagagacc ggtgcttgga tgccctcgca atttgacaat cctgcaaatc
     6301 ccaaggttca tgaagagaca acagggcaag aaattatcgc ggtttttgga gaaaaaggac
     6361 ttgatgcctt tgtttctggt gtgggaactg gtggcactat ttctggcgtt gcgcatgcct
     6421 taaaggctgt taatcctgat atttctatct atgctgtgga agcagatgaa tctgccgtct
     6481 tatctggtga agagtcttct ccgcacaaga ttcaagggat ttcagctggc tttatcccaa
     6541 ataccttaga tacaaaggcc tatgaccaca tcattcgagt agcgtcagag gctgcccttg
     6601 ccactgctcg gtcaatcggg gctaaggagg gctttcttgt aggcatttct tctggagccg
     6661 ctgtttatgc tgctatccaa gctgctaagg agcttggaaa aggtaaaaag gtcttagcta
     6721 tattaccaga taatggtgag cggtacctgt ctactgccct ttatcagttt gattagaata
     6781 atcatataag caccagccct agcagctaga ataagctttc aagcataaat catcgctctt
     6841 acttagtcac cattaaaggc cagtcagcta gcatatggaa aaatgcttac tttgattcct
     6901 ttttaacaat aaacatagca taccacgcct aagcgcccca gagcttctag cttcttggaa
     6961 ataggctttc ctagccgctt tcaccacagt aaaaaagact caagctagta ggctaagatg
     7021 ttcaaagagg actagcaatc acaattggct ttttttgaag atagctttga gataagtaag
     7081 gtgactggtc cagagctgat agcaaaaaac cgaggaacag ttcatatagc tgtttctcgg
     7141 ttttttatgt ttccaagtct gtttacgatt tttcctgctt aaagtggtct aagccttcct
     7201 caatccaatt gggtaagctg gcttcaagag gcttaaagcc aatcttataa cggctgtttg
     7261 aaaagcgatg atgacttgac acatgatgct tttcctcctc caaagttctc aaggacaggc
     7321 tgaccttatg actgtattcg tcatagtcaa tgacctgaac taaaaccgcc tcaccaagtc
     7381 ttaggatctg atgaatatta tcaataaatc ccgtcttaat ttctgaaata tgaatgagac
     7441 ctgttgtccc attttcaagg gcaacaaagg ctccataggg tttgattcct gtaatggtcc
     7501 catgcagctt atcgccaatt ttcatcaatc aaatacctcg atggcctcaa tgacaacgtc
     7561 ctcttttggc ttgtcttgtg cccctgtttc gacagcagca atgttatcca agacctgata
     7621 agaggcttca tcagccaact gaccaaatac tgtatggcga cgatccaggt aaggagtccc
     7681 cccatgttca gcgtaggctg ctgcaatgtc ctttggccag ccaccacgct ctaattcctt
     7741 ttgagaataa ggaaggcttg tattttggac gataaagaat tggctgccgt ttgtatttgg
     7801 tcctgcatta gccatcgaaa gggctccgcg aaggttgtac aattcctctg aaaactcatc
     7861 ctcaaagctt tgaccataga tggattgccc acccattcca gtgccagtcg gatctccacc
     7921 ttgaatcata aaatctgcaa taatacgatg gaaaataaca ccattatagt agccttcctt
     7981 agctagacct aagaagttag caactgtttt tggagcatgc tctggaaata aagccaatgt
     8041 cagctcacca tgatttgttt tcatcaccac tcttggtcct tcatggccag ccaaatctag
     8101 ctgcggaaaa tgtaattctt tgtcaatcaa acctaattcc tccaaggcat ataaaatgcc
     8161 gttttcttca actgttttag taataaaatc tgctttttct tgtaattgtg ggtgagaaac
     8221 ccccatagca atgctgatgc cagcataatc aaatagctct aaatcattga gctcatcacc
     8281 aaagaccagg atattttcag gccttaagcc caaatgctca acaacctttg atacacctag
     8341 agccttagag gtgcccttta ggaccacatc agaggagtga tcatgccacc ttactaggcg
     8401 aagctgctca gccaattcaa caggtaattg caggtcatct cccttgtcct caaaggtcca
     8461 catttggtag acatcatggt gctcattgta atccgggcat acctctagtg tggagtaaac
     8521 cttatcaata gcatcactaa tcatctcgtt acgagctgat aagacagcct cgtgacgtcc
     8581 tgccatgcca taatcaatgc cgactgcatt ggcccatttt ttataggcta caacagtgtc
     8641 tgctgggata ggtgcctgaa agataatgtt tttttgattg tccttcacat aagcaccatt
     8701 tagcttaaca caataatctg cctgtaaatc ctgaacctcc ttgggcacac catatctggc
     8761 gcgacccgaa gcaattcctg ttaggatccc ttttttcttg agctctttga aaaccctctg
     8821 gatagactct ggcatatagc ctgtgttctt tacgcgcagg gtatcatcta tgtcaaagaa
     8881 aaccatcttg attttcttgg ccttatactt tagttttgcg tccatacttt cctccatgca
     8941 atagtactat tatagcatta atgatcatct tgaggcacta aatgatgtcg gaaagcgtat
     9001 acaacagcct gagtacgatc atcaacctgc aatttggcta aaatatttga cacgtgagtc
     9061 ttaactgtct tcaaggaaat aaaaagctca tcagcaatgg tctggttatc atagcccttg
     9121 gccaataaat gcaaaatatc gtattcacgc gctgtaagct cttcatgtaa attaggctgc
     9181 tgatcatgtg ccttaatctt cttgtcaacc tccgtttcaa tggcaagctc gcccttagca
     9241 acctttctaa tggcatttaa gatttcagct gcacttgatg tttttaacat atagccctta
     9301 gctcctgcat caatgacagg gtaaattttt tcattatcaa gataggaggt taacaccaac
     9361 acccttgctt ccttccattt ggagagtatt tctagggtcg cctctacacc tcctaattca
     9421 ggcattacca aatccataac cacgacatct ggtctcaatt caagggcaag ctcaactccc
     9481 tcacgaccat tagaagcctc acctatgaca tcaacatctt gctgcaaatt taagaagctt
     9541 tttaagccca ttcggaccat ttcatggtca tcaactaata ttacggttat attactcatc
     9601 ttcatctccc atcacaagtg gcagtctaat gtccatcgaa acgccctttc ctttttgact
     9661 aatcaaacga agcgttccag ccaggtcatt cacacgatct tcaatatttt taaggccata
     9721 gcttaattcc ctaacctgac ccatgtcaaa accaacccca ttatcaacca tttttagctg
     9781 tagttctgtt ggtgtttggt tcaagtacac ctcaaggcgg ctcgccttag catgcttgag
     9841 ggtattgctg ataaattcct gagcgatcct aaagagatta tcctctatgg cctttggcag
     9901 agtgccaata ttttctttat agacaacctc aatgccgctt ttatcagtta gttccttgag
     9961 aatcatcgta aagccctctg acaggctacg atttgccaat tctgtcgggc gcaggtgcaa
    10021 taataaaatg cgtaaatcat tttgagcatt ttgcagcatg gcttcaacag taactaattg
    10081 ttgctgtagc tgctccttat ccatctgatc taggctcata gaaacccctg acaaaatcat
    10141 cgacgaagca aacaattctt gactaacagt gtcgtgcagg tctctagcga ttcgtttacg
    10201 ctcctgttga acaatttttt gactatctaa aatataagca ttctcttttt tctggatatt
    10261 ggttgttata tgagacattt tcgcagaaag tctggtcaaa ttcgtgttga tttcagaggt
    10321 ctcctccaaa tgaattcttt gattgttgag aatcctgcgt aaatttttat tgatgctccg
    10381 cttgctatta tcatctaaaa taatccacaa caaaagcaac agcaaggtta cagagatgat
    10441 aagcagcaca actgaaaaca ccaagcgctc tagctgccat aaatggctcc gcaagtagtc
    10501 aaaggtgatc cccagattat ccatcacaac aaaaacaatt gataaaatgg ttatagtcga
    10561 ataaagccag accaaagcat aatacctttt tttcatcgtc tagccacctc gacatttcct
    10621 gctatagtgg atacgataat cttaaccttc tttaaactgc tgtcctcggc ctctcctagg
    10681 gtgatggatt catttcgtaa atcgtactct tgaagctcaa aaaaatcaac actagcatag
    10741 atagagctga cctctaaggt aacagccaca tcaataggca ctaggatctt tgtgttgcca
    10801 aagatctttc tgataatgat gacattgtcc attccagtca caatcacatt tgtcagatca
    10861 atcgtatcat tgccagaggc acgaataata ttgatatcct caaaggaata ataatcactt
    10921 tcatagttag ctgcgccaag ccattgattt ttgacctgtc gcacagtcat tttttcttct
    10981 gcaaaccgaa tgagggcaaa tcgattcttc ttttttacct gtgaaaaatg attgataatc
    11041 acatacacaa tccccaacag aaccgccata ataacataag ggttcagcat aaaaattaag
    11101 aataaaagca ataagctaac tgttagcaaa aagctattgc gggtatcttg attataaaaa
    11161 cgcagagcca ataaaatcaa gaccaaaatt aaaataaagc ttgataagtc gttggccaaa
    11221 atggtcataa tccccatagc cagcagcatg cattcaacaa gcagaaagaa ttgaaatttt
    11281 ttcattagac tccttccatt accctgacat tttatcaaaa attaagcaaa aattcaccct
    11341 tgagtggcat tctagtaaaa aagaatacct agcttagcaa ctatgggcaa gccagatatt
    11401 ctatatccta tttacgttta cggtgttgta acagcgtcat tttgacctaa ttcggtatga
    11461 ctgcttgagt ctgttgtatc tccagctgat ggattaggag ccgaggtatc agagctcgat
    11521 gagctgcttg atgcacgtgt ctcctcaggg tagaggtaga ggctaatatc acccttttca
    11581 gaaaggctaa tctgggtacc ataatacggt gtttgcccac tgacaaccgc ctttgagctt
    11641 ggggagctca cctgcacaaa gcctgtcgga gagctggagc ttggtacata ggccttgatt
    11701 cttgcggcat caattcctaa agctgttagt gtattgactg catctgcata gctgtactca
    11761 gttaccattg gcatgatgac tgtatcaccc actgctacac tgagggtaat cttggattta
    11821 ccagctgggt taaatttttc tcctgcgctt ggagactggc taataacggt gttttcaggg
    11881 tattcatttg tcacgatacg ctcaatcttg atttttgact ttggtacgcc ataggtctca
    11941 gtcagactgg tcatcacatc ttgataatcc tgtcccttat aattttccat ctcaaagcct
    12001 ttatttccga tcgaaaggta aaggtcaacg ctggagcctt ttcgcttagc tgagccagct
    12061 tgaggatttg tcttaaccac ctgatcctca ctaactgtgt cactttcaat ctgatggacc
    12121 ttaccgacct ttagtcccgc ctcctccaag acctgcttgg cagcattgag actagagcct
    12181 gtcacatcag gaaccttaac cgtagttggc ttggtcaaga ccaaataagc aaaaagagcc
    12241 acaccaacaa caaaaaagga aaacaagatt tttaagagtg ttcctagaaa acgcccattt
    12301 tttttctttt tttgaggctt ttgcagagta tccatctggc tagtctgctc aagtctagca
    12361 tcaactgccg cagatgcctg actagcattt gataccttag gtgctgttac aggagtcggt
    12421 gttacctttg gcaagggctt tgtgctttcg acatcatcaa agacaacctt acgctcacga
    12481 ctgcggttat agctaagggc tgtcatcaaa tccctgctca tctcaaaggt cgagcgataa
    12541 cggtcactta gctttttggc agtagcccga ataacgacgt tttccaaggc ttgaggcaca
    12601 ttaggatttt catcaatgat agagggcagc ggcttttgaa aatgctgcaa agcaatcgtc
    12661 acagcgctat cgccatcata aggaatatgc cctgttagca tttcaaagag cataattccc
    12721 atcgcgtaaa tatcactttg aatcgtcgct ttagaaccac gcgcttgctc aggtgagagg
    12781 taatgcacac ttcctagcat agaatttgtc tgggttagac tggtctctgc aaaggcaacg
    12841 gcaatcccaa aatctgtaac cttaacaaca cttgatttgg tcaaaagaat gttttgaggc
    12901 tttaaatccc tgtgaacaat tcctttttgg tgggccagag tcatggcaga aagaacctct
    12961 tccatgattc tcaccacctc attgttagat aatggcgcat gatcctgaat gtattttttc
    13021 aagtcagagc catcaacata ttccattact aaaaattgct gtccgtcttc ctcgcctata
    13081 tcccgaatgg caacaatatt ggggtgattt aattcagcca tggctcgcgc ttctctttga
    13141 aaacgcgcaa cagcaacctg atctgtttga taattggtcc gcaagacctt aatggcaacg
    13201 tcctcattat ccagaatcaa atcgtttgct aaataaacat ccgccatacc accgcggcct
    13261 atagatttta gaatgcgata acgaccagca aatagcttgc caatctgaat cattctgctt
    13321 ccccgctttc cttatgcacc aaagcaacgg tgatgttgtc taggcctcct ctttggtttg
    13381 ccaggtcaat caaggcttga tttttctcat caaggctgat gtcttgacat aatatgtcaa
    13441 caatctcctc attagcaatc atattggtta agccatcact attaatcact aggtaatcgc
    13501 ccttttctaa aaccttgaca cctaagtctg gctctaccgg tgaagcttga cctatagatt
    13561 gtgtgatgat atttttttgt gggtggctag cagcctcctc ttcggtaatc tgaccagcct
    13621 tcactagggc attaaccaag gaatgatcac tggttaaaag actataattt ccctcatgaa
    13681 ccaagccgat acgagaatcg ccaatatggg cataaatcgc attagaatct actagagcaa
    13741 ctgcctcaac ggttgttccc attcccttat agtcttcaga ttgtcccaag tcgtagatac
    13801 gttggttctc tgcttcgatg gttgttaaca accaatcctt gatctgacta agctcagtaa
    13861 aatctgtctt aacccactct ctacctaggt ctgtaacggt catctcactg gcaatatttc
    13921 ctgccctatg acctcccata ccatctgcta ggataacaag ggtaatgcct tttttattat
    13981 caaatttgtt gataaaatct tgattgtttg agcgcttttg cccaatatcg gtttttaatg
    14041 aaatcttcat ataatctttt ctgactaggt cagtctcctc ctaaatacta caagactcgt
    14101 ctgacttgcc caataaagaa gccatcagtc tggtattgct ctggtgtaat cataagacaa
    14161 ccgtccttga caatatctgc ttgtgcatgc ttgagtgtta cttgttcaaa attaggatga
    14221 cgttgtaaaa atttgtcaat aacttggaaa ttctcttcat caaaaatcgt acaagtgcta
    14281 taggttatta taccaccttt tcgcagcgtt tgacaaacgc tagacaatat ctccagctga
    14341 atttcctgca attgctggaa gtcctgccct tccttgttgt atttaatatc tggcttacgc
    14401 ctgatgaggc ctataccaga gcagggagca tcaactaaaa tcttatcaaa gctgttcttc
    14461 gcaaaatgct tatgaacctc tctagcatca agcaccttag tttcaatccg atctgctacc
    14521 cctagacgct tagcattttc attcactaag gccagcttgt gctcatacaa atcaagggcc
    14581 actactttgc cgctcgtcaa ataagaggca atgtgagctg ttttccctcc gggtgcacta
    14641 caagcatcta aaatcatttc ctgcccttga atatccagcg tcggggcaac tagctgactg
    14701 gtctcatctt ggatcgtaat gtccccattg atgaaataac tgctggcagc aaaattgcca
    14761 gctctcttgg tcagaccagt cctagcaagt aatgattgct ctgatcctgt tgcctgcttg
    14821 atctcatcaa gctttgtcag atctgtgaca cgtatgctgg ctctgcttct cacaaaaaga
    14881 ctttccatga ttgctacagc tcgctcctcg ccaaattggt cgatcaattt tttgactagc
    14941 cagaccggta ctgagtaagc aacagcatag tatttgtttt ttcgcttgat gctcttgata
    15001 tctggtaagg gcttattggt cagctggcgc aaaacggcat tgaccagctt atctgctcct
    15061 ctgccatgag ctctcgcctt ggcaagatta acagcgtcat taacaatagc atgagcaggc
    15121 accttgtcta ggtaagccag ctggtaaagg ctaagcatca agagataata aacccattta
    15181 tccagcctgt ctcggtcctc aatatagtga gccagatacc attctagggt tatcttccta
    15241 gagatagtcc cgtaaacaat ctctgtgact agagccttgt ccttatcact taaaaactga
    15301 ttcgccagct ggtgcttcaa ggcaaggtta gaataggctc catgatcaaa aatatcctca
    15361 acgataagca gcgcctgtcc tctagctgat tttttccaat cattcgccaa ggacatcacc
    15421 cacctctagg cttctgccaa taccatttaa aaagtcaaca ataggcatct ttggcttgcc
    15481 tgctggttga acgagcgtca aggatagagc cccctcacct gctgctacga ccaatgcttt
    15541 tttagtttta gcgatgattt gcccagcaga tccagagcct tcagccaatt cagcctcata
    15601 aattttgaag cgctgcccat ctaataaggt atgagccacc ggccaagggt tcattcctct
    15661 gatatgatta aacacctctc ttgctggctt tgaccagtcc agtctttctt cttctgctga
    15721 aagattggga gaaaaggtgg cttggctatg gtcttgagga actggcttta ggtcaccaga
    15781 caagtaatca ggcaaggttt tcaataataa atctcgtcct agaatggcca gcttatcaaa
    15841 catggtacca acattatcag tatctaaaat tggaaggctt gcgcttgata tcatatcccc
    15901 agcgtccatc tccttaacca tctccataat ggtaactcca gcttccttgt caccattgat
    15961 aatagcataa tggatcggag cgccaccacg atatttagga agtaaggacg cgtgcacatt
    16021 aacagcaaat gtcaccgaat ccaataagac tgttggtaaa aattgcccaa aggctgccgt
    16081 tacaatcccg tctgctccta atgccatgat atctgctagc tcctgtgaac cagatagctt
    16141 ctcaggctga aaaacaggca gctgatgtgc aagcgccagc tttttaacag gcgtcattgt
    16201 gatgtctttt ttgcgaccaa ccgcacgatc aggctgggtc acgaccgcta aaatgtcata
    16261 ggctggtttt tctagtaagc cctgcaaaac agttgctgaa aattggggag tgcccataaa
    16321 aattaatctt gtcatctatg tcctctattt tctttctttt tcattatagc atagcttggc
    16381 gcaaagtccg gtaaagaaca cttacataaa gctctgtggc tcctgatcaa tgataacctt
    16441 tagctcgcga ttatcctgct cttggctcca atcaagaatt tgattcaggg tagcttcaag
    16501 ctgatcctca aagcgatact tcaaaataat ctgataatgg taaagattgt gcgttcttgc
    16561 aattggcttt ggcgttggcc ctaatattct gatctgatca gacaagccct gcttcaatat
    16621 ggtcagcagt tgataggcct ttttgaccac ctcttgctca ctcttatgcg atagggtcag
    16681 acctactgtg aaataatagg gaggatagcc tagctttcgt cgaatcccca tttcataagc
    16741 gtaaaaggct tcaaaatcct gctttttggc cagttgaatc gcgtaatgct caggattgta
    16801 ggtctgaatc aggacttcac ctggcttgtc tgcacgtcct gcacgtcctg caacctgagt
    16861 cagcaattga aaggttcgct ccgatgccct aaaatcaggt aaatgcaagg aagtatctgc
    16921 atttaaaaca cctactaggg tgacgttggg aaaatccaac ccctttgcaa tcatttgtgt
    16981 cccaagcagc acatcagcat caccatttcc aaactggctt aaaatagcct catggcttcc
    17041 ttttttacgt gtcgtgtcta cgtccattcg taatattcta gcttccggca acacttgctt
    17101 gagctcatca taggcttttt gcgtccctgt tccataatag cgtatgcttt tgccttgaca
    17161 gctagggcat agcttcggaa tagccctttg aaagccgcaa tagtgacaat tcatggtttt
    17221 cgtatccatg tggagggtta aggaaatatc acaatttgga cattgatcaa catagccaca
    17281 atctcgacac atgataaagc tagagtagcc acgcctgttg agcatcaaaa cagcctgctc
    17341 ttttctagca agacgctctt tgagtttatc aatcaaataa ggggtgaagc tgctaacctc
    17401 ctgctgacca atataatctc gaaaatcaac aatctcaacc tgaggcatac tggcaagagg
    17461 attggctctc tcagtcagct ggataaactg atacagtccc ttgctggctc tagcgcgact
    17521 atcaatacta ggggtcgctg agcccatcac taaggcagcc ttatggtgcc ttgcacgaat
    17581 gagagctaca tctctggcat ggtatctggg attagattcc tgcttgtagg tggcctcatg
    17641 ctcctcatca ataataatgg ctccaatatt ttctaaaggt gaaaaaatag cagagcgagc
    17701 accgaccacc actctagcct gccctgtctt aattttctgc cattcgtcaa atttttctcc
    17761 atctgacaaa cctgaatgca taatagcgac ctgtcttcca aagcgggaaa taaatcgaga
    17821 ggtcatttga ggcgtgaggg agatttctgg cactaagaca atagctgtct ttccttgctc
    17881 aagcacatgc gcaatcacat gaagatagac ctctgtcttg ccagagcctg taataccttc
    17941 cagtaaaaag ggcttagcct ctctgccaac agccttcgta atctggtcaa cagcttgctg
    18001 ctgctgctga ttaagcttta agagtggggc tgccttgatg tgattgaaat aatcctcact
    18061 gcgattgaca cgtcgctcct caagctcgat cagctggttg gtcacaaaat agctaacaac
    18121 ctctctagaa taatcctgat aaagcttggc tagcttatct ttttgtggat tggctaacaa
    18181 ataagccttt aaggcttggc gctttttagc ccgatttgaa atcttatgct cctgtaaggc
    18241 taatctattg acctgatagt aagtctcggt tttgattgtc tttttgtcct tggctagata
    18301 agttgcccta atcttaccag actgtatcag cctaaggaca cgtccctcct gctctggact
    18361 tagcttagaa taaagcaagg aatccccatt agagaaaaca tcagcaaggt cagccgcagc
    18421 taagtcagct gtcggggtga gcagccgatc gtaatgagaa ttaagtaggc taggaagcat
    18481 tgcctttaag agggtgattt tgtaggaaaa gactgtttgt cgtaattgct ctgctaatgc
    18541 cacctgctcc tgatttaaaa caggctcagc atctaaaact gaccaaatag ccttcaattg
    18601 ctgcgttgat tgactagaaa agccaataac aaagccctgt agcaacctat tgccattacc
    18661 aaaaggcaca tgaacgcgag aaccaatctt aaccagagat aatagctcat ctggaataag
    18721 ataagaaaag ggcttatcgg tttgcatcaa gggaatatca acaatgacct gtgctatgtg
    18781 ttgcattttg acttcctttc tatcaagaaa tggacctgca atatgaaaaa aactaagatt
    18841 gactcaacct tagatttttt ctccctcttc ttctttttct tttgcaatct gctcttttat
    18901 tttacgctct tcttcttctc ttgctaaacg ctctgcctca atccttgcac gaacagccgc
    18961 acgcttagca gcaggatccg ggtgaatcac aacattgcct gactcaatct cctctagtgc
    19021 ctgaagtgtt gatttgacag acttaaagga ctgtgtcggt gcagcacctg cttctaattc
    19081 atgagcacgc ttggcctgta aaataacaag tgaatatttt gatgggactt tatctaataa
    19141 agtatcaatt gaaggtttta acatcatggg ctttactctt ttctatttct atcatctgag
    19201 agattttgtt gttttaatca tttgatcata gcgaccaatc acacgctcaa cgcgaaaatg
    19261 ctcggtctca ataatacgct tgacacgctc tgcagctaaa ggaacctcgt cgttgaccac
    19321 agcataatca tactctcgca tgagcgcaat ctcttcctta gctctttcga tacgcttggc
    19381 aatcacctct tggctgtctg ttccacgacc aaccaaacgg tcctgcaatt catctaagtc
    19441 tggcggcgtt agaaaaatga agacaccatc aggcacctta gccttgacct gcaaagcacc
    19501 ctgtacctca atttccaaaa agacatcaat gcccttatca agggtttcgt taacataggt
    19561 taagggagtg ccatagtaat tgccgacata ctctgcatat tctagcattt gaccattttt
    19621 tattagctct tcaaattctt ctcgtgtgcg gaagaaataa tcaaccccat caacttcacc
    19681 tggtctctgt ggacgtgtcg tcatcgaaac agaatattca aatttatgat ctggcgttga
    19741 aaaaatctct tgtctcaccg ttccctttcc gacacctgag gggccagaga aaacgattaa
    19801 caaaccgcgt tcagacattg tgttctcctt attgattgct ttctaatagt ttatcaaaaa
    19861 ggctatcgtt tttcaagaca attatcagcc caatcctaag aaagaaaagg aagagataga
    19921 cgccttctca aagctagagg ctaaactctg gcttttgaaa agcatacact ctttcctttt
    19981 tatttcgcat aatctattgc tcgcaactca cgaataacag ttaccttgat atttcctggg
    20041 taatccaagt tattttcaat cttttctctt accttgtgtg agagaaccac aatctcgtca
    20101 tcagaaatct tttctggctg aaccatgatg cgaatctcac gaccggcttg gagggcaaag
    20161 ctactttgaa caccatcaaa gcttgttgcg atttcttcaa ggtcacgaag acgcttgata
    20221 tagttttcca cagattcatt gcgggcacct ggacgagcag agctaagggc atcagcagca
    20281 gctaccagaa ctgcaataac cgaatccggc tcgacatcgc catgatggct ggctatggtg
    20341 ttcacaacaa cagggtgctc cttgtacttg cgagcaaact ccataccaat ctcaacgtgg
    20401 cttccttcaa cctcacgatc aatagccttg cccatatcat gcaagaaacc tgcgcgacgt
    20461 gcaagtgcca cattttcacc aagctcgcca gctaaaatac cagctagctt accaacctcg
    20521 actgagtggc gtaaaacatt ttgaccaaat gaggtacgaa actgtaagcg ccccatgatc
    20581 ttaatcaaat ccgggtggag gttaggtgca ccgatctcat aggcagcagc ctcaccatac
    20641 tcacgaatcc tattgtccat ctcaagacga tttttctcaa ccaattcctc gatacgcgcc
    20701 gggtgaatac gaccatcagc aatcaaggac tctagggtca tacgagcaat ctctcgacga
    20761 atagggtcaa agcctgataa aacaaccact tccggggtat cgtcaatgat cacatcaatc
    20821 cctgtcagac tctctagagt acggatattg cgaccctctc gaccgataat acgccctttc
    20881 atgttatcat caggcaagtg cacacttgta atcgtctgct cagtcacata ctcaccagcc
    20941 atacgttgca tggcctgtgc taacaggtcc ttagcagtct tgtctgtcct gtccttgatg
    21001 tcacgctctg catcacgaat gcgtgttgcg atctcatgcg tcagcttgtt ttcagtttcc
    21061 atcaggataa cctcacgcgc ttctgcaatg gtcatagcag caactcgttg gagctctgct
    21121 cttttgtctt cctcaagttt ttcaacctgt gcctgtcgct catcaatgtg cttagattta
    21181 tcggtcagac tttgctcttt gctatctagt actttttctt tacttgatag attttcatcc
    21241 ttacgatcaa gagttagagc acgctctgcc aagcgcgtct ccagctgttt aagctcttgt
    21301 ctttcagatt taaattcctg ttcaatttct tcacgatact ttcttgcctc ttcctttgct
    21361 tctaaaagta attctttacg acttgcttta ctttcacgtt gtgctgtctt tttgatatga
    21421 gcggcatcgg cctttgcctt gccacgaata tcaacagcat cctgttcagc gtttaaaaga
    21481 gtcaactctg cagcttcctt cgcagacttg agtctaatcg aaataagtgc ataacctaat
    21541 attacaccaa tgaggccaca gacaagtaac gttatgatat taattaacat gtctttacct
    21601 caataatagt ttagttttca ttaacagaaa gccatctctt agtctatcat aaaatgaaga
    21661 tttagacaat ttaaaatcca cctacatttt tctaaaatct agtgatttta tgttatgata
    21721 ttgataaaaa taaaaaggag tttcttatgc caaaagaagt tattgttgaa agctttgagc
    21781 ttgatcatac tattgttaag gcaccctatg tacggctaat ctccgaggaa tttgggcccc
    21841 agggagatgt gattacaaat tttgatgttc gacttgttca gcctaatcag gctgccattg
    21901 agactgccgg tttacatacc attgagcatt tattagccaa gctcattcgt caacgcattg
    21961 atggaatgat tgattgctcc ccctttggct gccgcacagg ctttcacctc atcatgtggg
    22021 gcaagcatag ctcaacagat attgctaaga tcatcacgtc cagcctagag gaaattgcta
    22081 caagcatcac ttgggaggac gttcctggca caaccattga atcctgcggc aattataagg
    22141 atcacagcct ttttgctgct aaggaatggg cacagcttat tctcaagcaa gggatctctg
    22201 atgatccatt taaccgccat gtcacctcat aaaacgaaag cctctctttt ctgctaatgt
    22261 gaaggaggct tttaatgtat tcaaaaaggt gccaaaggca aggctcaatg cccttacctt
    22321 tagcacctgt gataactaga gtatccagtt caggatcaca ccttgtcttc taagcattaa
    22381 tagtctaagt cctctgcatg ccccttgcca tttccgacaa aatagcctgt tttgcaattc
    22441 aatgaaaaga ggtaggtgcc atcaggctta aacatgttgt aatagccatt cccattgata
    22501 atattgaccg gctctaggat ataatcattg cctgaaatat agccccttgc ttgtgaggta
    22561 gccacaatac gctcaagcac acctggatta aaggcccaag cagggtttcc tgtatcagca
    22621 atcatagcct gattgtaggg cacacgagac aggtcacgct gcaatattga agggtcatag
    22681 cctgtaatgc catacattgg agccactgga gctggtacag caggaacctg cggagctgca
    22741 gggcttgctg gtaaggcaga agcagctgga gtgctagctg cttgggtagc agacctgctt
    22801 gctagctgct cacgacctgc cttgatgctt gattgtagca atgaatcaag ttttgcatta
    22861 ccagtggtta gcgtatcact agctaggtca tcaaaattag catcagcttt gacctcagct
    22921 gcaatctttt caccattgac aattgcagct gttgtaaatt tcccattaac cgcctgaata
    22981 gctgttactt gctttttcag cccagtaacc ttttccttag ccttgtcata ataggctgtc
    23041 ccttcaagcc tttttaaagc agtctccaaa ttcggtaact gatcaaaggc gctatttttt
    23101 agggttgttt tatcattatc tgtgaaaaat gtcttgtaaa gatcttcaaa agccttagca
    23161 ttagcctttg ttttgttggt ctgattagct gttgatgctt tgctccttgc ttttttagaa
    23221 acagtagcct ttgactgagg cttatgctta gacagctgat agatatggtt gagggcaaag
    23281 gctgaggcta caagggttag cgtggctaac aaaatagcaa acagaggctt tttcttttta
    23341 gacctacgac tagcatagct atctgataaa atactctcta cttctgcagg tcgctcgcta
    23401 actgcgtcat cagctagctg cccagtaaaa tcactagcag aatcagtagc tgccgctgaa
    23461 gtgtcagctc tagctgctag aggctcaatg aatgaggtct caccggctgg cttctcctct
    23521 gttgaagcct cgtccactgg ctcaacatca actaagccgg ctttgctgag ctcctctctt
    23581 tgttttttga taaagttatc cagacttgct gtatctaact ccatatactt tgcatcaaac
    23641 ttttgtgatg acacttcgtt acgatgccgc ttaatatatt tgtctaaaac actatcatcc
    23701 tcggtaatcc ctgcttttag ctctgagtcc ttgcgtactg cctcaccgat tgtcattttt
    23761 ttggcttcat gaagctccaa attttggctt tctgcctctg attcaaatgc tttgcttttt
    23821 tctgacacgt tttttacctc tctatatcag attgcgcttt accctctctc cataaaattg
    23881 atacaaatca acccttagag taccattata aagcttacgt tttttatcag ctttttgacc
    23941 atatttttgt tcaaaatgat catcactcgt caaaataaac ttgctccagg taactaatgg
    24001 agcaaagacc tgtaccatct cattatacaa gatgtctact gctttgtcat caagcaaacg
    24061 ctctccataa ggaggatttg aaatgatgac accgtttatc ttgtctgtac ggaaatcctg
    24121 caagcgcatt tgcttaaagg taatgatatc agccaagcca gcctcctcag catttctctt
    24181 ggcaagctca accatacgac cgtcaatatc aaagcctgaa atatccagct caatatcata
    24241 attagcctct ttttcagcag cgtcacgaac cttttgaaca cgatctttgt ccacccagct
    24301 ccattcctca aaggcaaagg agcgattaaa gccaggagcg atattcattc cgatgagagc
    24361 cgcctcgata caaaaggtcc ccgatccaca ggtgggatca accaagggct tatccggaaa
    24421 ccaattagac agcttgagga tagctgctgc catgttttcc ttaataggag ctcccccttt
    24481 ttccacccgg tagccacgct taaataggct tgagccacta gtatcaatca tcagggtagc
    24541 ctgatccttt aagattgaga cctcaatttt gaactcagcc cccacctctt gaaggggaat
    24601 atgctccggt ctatgaaaat gctgctgcaa ttttctgaca atggcttttt tggtaatggc
    24661 ttgaacactt ggctcgttgt gcagggttga cctgacacac ttagcctttg caataggaaa
    24721 cctagcacct aagggcaaat aatgctccca atccaaggca aatacgccct gaaacagctc
    24781 ctcaaagctt cgtgctggga actgacctac aataatctta atacggtcag ccgctcgcag
    24841 ccaaagattt gctttagcaa tagcttcaat atcgccttca aagaagacct tgccattatc
    24901 tactcggcag tcaaatccca aggcccttaa ttccttaccc acaacagcct ctaggccagc
    24961 tgctgcagtt gctactaatg taaattgttc tttcatatga ctctttctat cctaaccaaa
    25021 taaaagctag catatgctag cttaacctat tatgcaattt tctataagcc atgttttgtt
    25081 ccagaaataa ctaggtatta tctccttcga taatcatctg tctactgttt gtcaacagtc
    25141 aggatagctt gttcgtttcc aactatccca tgcccctacc aaagtttggg ttgctagctt
    25201 gaggggttta ccgcgttcca ctttttacgt ttccataaaa acttcgtcac tgtggcactt
    25261 tcagagctac tctggcatat caaggactta gccttttcac tcgccgtaat gtgtcaaaca
    25321 catccctagg cttatttgtt cgcctagcac aaacactacc agcatcacag ccggtgctag
    25381 catggacttt cctcatagta ttgcaatact acgcgattat ccaaaaattg cacatctaca
    25441 ttactcaata atttgctttc caaaaacctc tttttccagc ttgctaatgc gctttagcat
    25501 gtcaaaattg gtggctgact gtgctactct ggttggctgt gataccgcct gagagctgcc
    25561 tgctaaagga tcacgcacct gagccttagc cttttttaag gcttcatttt cagcctttag
    25621 ggcctcgatc tgagcattga aatactcata atccttgatg acgttatcaa ggaattcgtc
    25681 gacctccttc ttatcaaagc cacgcatact ggtcttaaat tcttgctcaa aaatgtcctt
    25741 tggactataa attatacctg tcattctata ctctccaaac ggtcaatctt tttcaaatat
    25801 caaactttga tatcactact tatgatacag aaaaataaat taaaaagcaa gtatttaaat
    25861 accagtgatt tttaaatatc actagctact catctgcaat gtcatttaaa cgctcaaagt
    25921 ttaggaaaga aagggggtaa cagggctgct ccttcatagc tgctaccaaa tagcttaggc
    25981 gcgtttcgtg ctcactatca taaaaaagat aggctccgtc tgtattgtga atcaaaaagt
    26041 gatggtagct ctttagctgt ttagggcttt catagctggg atagctatat ttgacaaaat
    26101 cagtctcccg aaattgctgc agctgctgct gattgcgatc attccaagtg ctgccatgcg
    26161 tttcaaaggc aaaaatagtc gctgtcttta aggggtaggt ctttttgagg tcattagcta
    26221 cctctaaagc ccactgctca aaccctaaat tcccagtaaa aataaaccag tctaccccct
    26281 cctcaagata agcaatcaga tctctttcta tcgctttttt gataatggca actcttttat
    26341 ccttttcact aaagatgccc agctcaaaac ttcgatagcc tgttacgaga attgcagtca
    26401 ttagatgtta tcctttcaaa aatatgttat aatgtgaatg cttaaattat tattaagtca
    26461 tgatgttagg agaacaatgg ttaactaccc tcataatcct attcgccaaa aggtgacccc
    26521 tcttcaaaag cagcaaaagc acaagcaagt agactttgct aatcgtggta tgtcctttga
    26581 agcatccatt aatgcaacca acgcttatta cttggccaag ggcattgctg tcattcataa
    26641 aaagccaact ccgatacaga ttgtcaaggt agactatcca agacgtagtc gagccaagat
    26701 tgttgaggct tattttaagc aggcttcaac gaccgactat tctggtatct acaaagggca
    26761 ttatattgat tttgaagcta aggaaacaag acaaaaaaca gctatgccaa tgaaaaactt
    26821 tcacgcgcat cagattgagc acatggctgc tgttttaaag caaaaaggca tttgctttgt
    26881 cctccttcac tttgcgacac taaaggaaac ctattatcta cctgccaaag cactcattga
    26941 tttttatcag attgataggg gcaacaaatc aatgccactt gattatatca gaaaaaacgg
    27001 ctttgaggtc aagctgggag catttccaca ggttccttat ttagatatta tagaacaaaa
    27061 atttttaggc ggtgattaca attaacaatc caaaaatcct taaattcctg aagtatacat
    27121 taggtgctat ccttagcctt atcattgtga caattacctt aggtggcctt ttgtttgctt
    27181 actatatcag cagtgcccct aagctttctg aggcccagct caaatcgacc aattccagtc
    27241 ttgtttatga cggtaataat catttgattg ctgacttggg ctctgaaaag cgtgaaaatg
    27301 ttacagctga cagcattcct attaatctgg tcaatgctat tatttctata gaagacaaac
    27361 gcttttttaa tcatcggggg gttgatctct atcgtatctt aggtgcagcc tttcacaatt
    27421 taacaagcaa aacaacccaa ggggggtcta cacttgatca gcagctgatt aagctagcct
    27481 acttctcgac aaacgagtct gaccagacct tgaagcgaaa agctcaggag gtttggctgg
    27541 cccttcaaat ggagcgaaaa tataccaagc aagaaatcct gaccttctac atcaacaagg
    27601 tttatatggg aaatggtaat tatggtatgc tgacagcagc caaggcttat tatggcaagg
    27661 atttgaaaga tttgtcctat gctcagctag ccttgctggc agggattcca caggccccaa
    27721 gccagtatga cccctacaca cagcctgaga cagctcaaag ccgccgaaat attgtccttc
    27781 agcaaatgta tgctgaaaag aacattacca aggctgagta cgaagcagct atcgccacac
    27841 ctatatcaga aggcctacag cctctccagc aacgcgccag ctatccaaaa tatatggata
    27901 attacttaaa acaggtgatc gagcaggtaa aggctgagac caacaaggat atctttacct
    27961 ctggtctaaa ggtttacaca aacatcattc cagaggctca aaaaaaactt tatgacattt
    28021 acaattctga ggactatgtg tattaccctg atgctgactt tcaggttgcc tcaaccgtta
    28081 ttgatgtcac aaatggacac gttatcgccc aattaggagg acgcaatcag gataccaacg
    28141 tttcctttgg aaccaatcag gctgtcttaa ccgatcgtga ctggggatcc accatgaagc
    28201 cgatcacaga ctatggacct gccattgagt ccggtgctta caattctaca gctcaaacaa
    28261 ctaacgactc tgtctactat tggccgggga cacacactca gctctataac tgggaccgga
    28321 gatactatgg ttggatgacc attcaagctg ctctcatgca atcacgaaac gtccctgcag
    28381 ttagggctct agaggcggca ggtcttagct atgcacagtc cttcctcagt gatctaggca
    28441 ttaattatcc agagatgcat tattcaaacg ccatctcaag taacaatagc agttctgatt
    28501 caaaatacgg tgcaagcagt gaaaaaatgg ctgctgccta tgcagctttt gccaacggtg
    28561 gactctatta caagccacaa tacgtcaata aaattgaatt cagcgatggg accagcaagg
    28621 tcatcgaaaa taagggcaag cgtgccatga aagaaacaac agcctatatg atgactgata
    28681 tgctaaaaac ggtactaacc tacggtacag gtactgctgc tgctatccca ggagttgcac
    28741 aggctggtaa aactggtacc tcaaactata ccgatgagga gctggcacaa attgttgaga
    28801 cacatggact atctcctgat tacgtgggaa caatggcgcc agatgaaaac tttgtcggct
    28861 acaccaaccg atacgctatg gcggtttgga ctggttataa aaaccgtatg acgccaattt
    28921 atggctacag cctagaaatt gcttctcatg tttatcgcaa catgatcagc tatctcaccg
    28981 gcggctacag cgacgattgg accatgccaa gtgggctcta tcgtagcggc ggcttcctct
    29041 acctaagtgg tacctataca aacagtagcg attatacaag ctctgtctac aacaacctct
    29101 atggtaataa cagctcagct tcaagccaat cctcagatga ggatacaact gaagacagcc
    29161 actcagaagc aaacgacagc acaacgtcat catcagagca gcaatcaagc tccaccgatg
    29221 ataagaaaac caactgataa caaaaaactg gttcaaatgt tctgaaccag ttttttcaat
    29281 tatttggcta aggcacccat cggatcccaa ggggcaagta cctgtggttc tgcctcatag
    29341 gctgctaatt catcagctgt tagtaggtcc ttgcgaacaa caatctggta agtatactcg
    29401 tccatccaag catcagaagc aacaaagtat cctttgtcac caaccttgtc tccccaagaa
    29461 ttttcaacct tccatttgat aggcttacca gtatcatcta aatcaacacc tgtcaaaacc
    29521 atagcatgtg tcattaagct ttcgctgtaa tcaaggcgac cagccttgtc ttggctcaac
    29581 tgaatatcca tacctgcctg aaaatcatag gtattaaggg ctagaatccc cttttgacga
    29641 tctgatacct gaccaacgtc tgaaccaaac caaacggact ctccagcctg catttgctta
    29701 atagcaagct ccttgaagcg ctccatatca agattaaggt agcgcacctc aggactgcca
    29761 acaacattac caagcatatc aaccgtataa gatttgccat aaggcttatc agctgttggg
    29821 gcgttgataa cagacacata atcagacagc tttagaccaa catatttttc ataaaatgcc
    29881 tgtggtgtga tgcccttatc agcatgatag tgattatcct tatcacgata agcaaaatca
    29941 aattgacgag gtggcaaacc aagattcatg gctaagaaat taaagatttc ctgaagtagc
    30001 tcttcttttt tagcctgtac tgcctgatga tcagcaccag cactgatcac atctcgaaga
    30061 atctgagcgt cctgacgcaa gagcttattg aggtattgat ttagctcacg actattgctt
    30121 gatgacacag actctgggta gactgatttt ggcacaacac cgtatttttc aaacagggct
    30181 acaaccatgt cccactgacc accgtcttgc tgcggaacgt ccaaaagaaa cttaacccta
    30241 cggctagtca aggcttgatc agcagttgca atcacctgtt ccataaacca gtttgatttt
    30301 tcgtatttgt cccagaaaaa ggtgtgtgct tgtgacaact caaaatcttc taatttaaat
    30361 tctgaaataa gcttatggcg aaaggtgttt aaggctgcaa acatccagca acgacctgaa
    30421 gccttttgat tagagacctt atcctttgtc aagtcaatgg aaaagacaaa atcattgtcg
    30481 atctcacttt gtcttgtctc caaggattta agcaagccat tgtgagtgat ggcattttca
    30541 agagctaaat atttagcatt agcttcataa ttagcatata gctgttctgt aaatgtctct
    30601 gttaatactg acatcatttt cctccaaaga taataaataa caacacctaa aaataaagtt
    30661 gacagaaaaa tccataaata ctgtcaattt cattttcaag gattacttct attatagacc
    30721 ttatttgata ttcttcaagt aaaaaaatta ggctaactta attttttaaa gctaagcagc
    30781 agctttccaa taaccagaca aaaagccatc tcaaaagacg acaaaacctg ctggactttg
    30841 agcacctaaa catgtcatat gtccacctca gcatgaactc aaagaagcta gctgtgtctg
    30901 gctatgactt cagtttaatc attagcttgc cttagccaca aaaagaatcg tctccactgt
    30961 agcaaaagtg cttgatataa caccatcggc taagtcaagg ggcccctgat agttaactga
    31021 aacatatggc aaagctaaaa ccaaagactt cttctcctta aagcctctgg tttttagtta
    31081 gctgagcatt ctcctttatc ttggctgctt taagataggg acaaatcaac aactacccca
    31141 atcccattta caaaaaagcc ctaagtcaga gccttcatag ggctaagggt gagggaagct
    31201 cttaggcaac agctactgga tttatgccta atagaagctc ctgtccctcc tcacctattt
    31261 aaaatagcat tggtttatct atagcctgtg taggtttgag gatcacttcc aaaagtcatc
    31321 aaaaatagta attggcagat ggcgcttgtg ctgcccttta tgccaccagt cttcaatcct
    31381 tgcctgagct tcagcggaaa tcgtatgccc ctctaagtaa tcatctatct cttgataagt
    31441 aacacctaat gctacctcat ctgcaagtcc tggcttctta tcctctagat ctgctgttgg
    31501 caccttctca tagaggctgg ggtcagcctt tagcaccttt aacaaggcct taccctgccg
    31561 cttagtcaag cgaaaaaggg gtagaatatc cgctccgcca tcaccaaact tagtgaaaaa
    31621 gcccgtaaca ttttcggcgg catgatctgt cccaatgaca gcaccagctg tttgaccagc
    31681 gatagcatac tgactaatca tacgctgacg tgccttaatg tttcccttat taaagtcaga
    31741 aatctcaagc cctgccgcct ctaaggctct tagctgacca tcaacagcct ctttaatatt
    31801 aaccgtcaag gcttgatcag gttgaataaa tgctaaggct ttttgtgcat ctgcctcatc
    31861 tgcctgaaca ccatagggca agcggacagc gataaattgg tactgctcat cacctgtttc
    31921 agcgcgcagc tcttcaatcg ccatctgagc tagctttccg gctaagctgg aatcctgacc
    31981 accagaaatc cctaagacat aagtctttaa aaaagggtgc tttaacaaat aagcctttaa
    32041 aaaatcaacc gactggcgaa tctcctgctt aggatcaatt actgctttga cctcaagctg
    32101 acgaatgata tcctcttgta atgtcatatc aaatcactcc ttttacaggc ttccttgcgg
    32161 attttgtcaa taagatgcat cttattttgc caaacatcaa gcgcaagatc cacagggtaa
    32221 tgctgcggat tcaagacacg cttatattcg tcccaaagct tatcaaattc ctttctagca
    32281 taagccttga tgtcttttaa gcttggcagc tgataaacga gctttccttt atcaaaaata
    32341 tctactagca aaggaacagc atcaaaatct ctgacggttt tattaatgta ggtataagtc
    32401 gggtggaaca tgtgaatttc ctctaggtca ttgacattaa cacctgtaaa ggtgatgtaa
    32461 tcgccttctg acttgccctt ttcgcggctg gtaattcgcc aaacctgctt tttacctggt
    32521 gttgatacct tttctgcatt atttgatagc ttgatagtat cgcgcatggt accatctgcc
    32581 tgctctatcg aaacaatctt ataaaccgct cccagagctg gttgatcata ggctgtaatc
    32641 aattttgttc caacacccca aacgtcaatt ttagcttttt gcattttcag gttgagaatt
    32701 gtattttcat ctaaatcatt ggaagcgtaa atcttagcct ctgtgaagcc ggcagcatcc
    32761 agctgctggc gtaccctttt agataggtaa gcaaggtcac cagaatccag acgaacaccc
    32821 aagaaattaa tcttatcacc taattccttg gccacacgaa tagctgttgg gacacctacc
    32881 ctcaaggtat cataggtatc aaccaagaaa atacaatcct tgtgcacact ggcataggcc
    32941 ttgaaagcat cataatcatt accataggcc tgtaccagag catgtgcatg cgtgccagac
    33001 acaggaatgt caaaacgctt tccggcacga acgttactag ttgcgtctgc tccgccaata
    33061 atggcagcac gtgtccccca aacagcagcg tccatctcct gagcgcggcg tgtcccaaac
    33121 tctaaaagtg gctcatcttc aataacagag cgaatacgag ctgcctttgt agcaatcaag
    33181 gtttggaaat tcacgatatt caaaagagct gtttctacta gctgacattg acctaaaggt
    33241 ccctcaacct gaacaatagg ctcattggca aagaccaagt ctccctcttg tgctgagcga
    33301 atcgttagct ctaaacgaag ctctctgaga taggtcaaaa aagcagggct gtagcctagc
    33361 tccttcaaat aagccaaatc ggtctcagaa aaggtcaatt gctcaaggta ttctacgatt
    33421 cgttgtagac cagcaaaaac tgcatagcca ttgttaaaag gctctctacg aaaataaacc
    33481 tcaaagacag cattacgatt atgaatgccc tgctcaaaat aaacctgcat catatttaat
    33541 tgatataaat cagtatgaag ggttaagcta tcatctctgt acatataagt aactccttaa
    33601 cataattgtt attattatac catatttttg gcatagacct gtaagattca actaaaatcc
    33661 tctgctcaag ctttctaaaa aagaagcctt gagctgctat taagcctgac atattttttg
    33721 ccagtacctt cctaaaaagt ctatagcaca agggcttatg gctttttaac aaaagcagtt
    33781 tcagttgata gcattcataa aaaaagattg aagaaattga ccaaaatagc ccctttcttc
    33841 aatctattta actcacacct tagcctttta acgctttttt acacttgagc tgactgtagc
    33901 agccaaagac tagaatccaa atgctagcac caattgcccc gatataggtg gacttctgta
    33961 aaaacagtga aataaaaaca aaggcaaaaa aggctagggt caatggtgtt gttagctgat
    34021 aacttggcat caaataacca tctggcataa agtcactgga ctgacgatat ttccaatgcg
    34081 caagcatggt caaagcataa atcgcaatat aaacaccaga tgatgaggcc gtaatcagcg
    34141 aaaaggcatc tgcaacaccg ggcaggatat taatcaaggc cgacacccca acagcaacag
    34201 cagaagcaat aatagcccta cttggtaccc cttgacgaga tagggtgtta atcctcaagg
    34261 ctttagtaag agcatttggg gtctcattag cgatttgata caaatgccga cctgtcgaat
    34321 acagggtcga atttagggct gatgctgctg atgttaagac cacaaaatta attaaagcag
    34381 cagcccattt aatcccaatc agcttaaaga ccatcacaaa gggagactcg tccgtaggca
    34441 actgatacca aggcacaatc gccataatag acaccaaagc accaacgtaa aaaatgacaa
    34501 tccgcatcgg aatctcttgg atggccttgg gcaagacctt tctaggattt gcggtctctg
    34561 aggttgtaat accaacaaat tcgatggcct gataggcaaa gaaaaccatc tgaaaggcca
    34621 tgaaaaattt caacttccca ttcggaaata gtgaaaaatg atccacaata ttggcaaggc
    34681 tggcatgacc gacatgcgtt tcaaagcccg ttagaaccat aaaaacggct gttgcaatca
    34741 aggctaaaat cgcaacaatc ttaatcatgg caaaccaaaa ttcagtctct ccaaagaccc
    34801 gcacagcaat taaattgatg gagctaagca acaccaaaaa aacgagctga atcagccaag
    34861 atggccaagc aggaaaccaa aactgaacat aggaggcgac agctgtaatc tctgccatgc
    34921 caataaagat cagggaaatc cagtaagaaa gcccagaaaa atagccccag cctggcccaa
    34981 tatattttgt aatgaaattg ataaaggtat gctgatccgg atcatagtat agcatctcac
    35041 caatagcccg catcatcaaa aacataaaga cacctgtaat catgtaaaca aagataatag
    35101 acggacccgt taaggcaata gaacgaccag ctcctagaaa gagacctgtt ccaatagtgc
    35161 ctgctatcgc aatgagctga acatgtcggt tttgcagccc ccttaccatg ccattctcaa
    35221 gttctttagt gcttttagct tcttttgtag acatttgact ctccattcaa ttaaaaaaac
    35281 accactatta tatctgtttt tcagaaaatg ttcaactttc tctaaggctt gcaaactaaa
    35341 aaggccaacc aagccttttt agcgttaacc tttttaagat gataggcttt caatgtaatg
    35401 gtagacgcct tgaccggcaa tggcaccatc tccaactgct gttgtgatct gacgcagctg
    35461 cttttgacga acatcaccga cagcaaaaat accaggaata cttgtcttca tttgatcgtc
    35521 tgtcacaatc cagccctctt gattggtaat gcctagctca gataccattt gagtaaccgg
    35581 aatcaagccg acatagataa agacaccacc aaagtcatgg ctagtcactt gacctgtttt
    35641 gacattttca atcacaacat tagagacctt aatatcgttt ccttgaatct ccttgacaac
    35701 agaatcccag ataaaatcaa gcttttcgtt ggcaaaagca cgctcctgca agatcttttg
    35761 ggcacgcagc tgatcacgac gatgcacaat cgttactttc ttagcgaact gggtcaggta
    35821 gatggcttcc tcaactgctg aatctcctcc tcctacaact aataactcct gattgcgaaa
    35881 gaaagcacca tcacagaccg cacaataaga aacacctcga ctggtgtact cctcttctcc
    35941 agcaacacct aaaagacgat gctttgctcc tgtcgcgaca atcactgttt tagtatcgta
    36001 gtgcgtatct tctgtgtaca cacgcttata atcaccacaa tcctcaaccc tttgaacaat
    36061 gccataaatg ttttcaacct taaatttttc aagcggctca tacatcttta acgatagctc
    36121 tggtcctgaa atgtgatcat agccaggata attttcaata tctgatgtgt tattcatttg
    36181 accgccaggt gccccctgct caataatgcc aactcgtagg ttactacgtg ctgcatataa
    36241 agcagctgtc ataccagcag gtcctgatcc aataatgagt gtatcgtaca tgggttaact
    36301 cctcttaata gtcttgtcat cattttaaca atagctacat cgtattgcaa ttatttcgcc
    36361 ttcaatacca ccagaatgct cataaaggca aaggacaaaa tcggaatcgt caaaatagca
    36421 accataatca tctcatataa aaatgcctgt ctctggagaa tggttttatc ctttttggtc
    36481 acagcacgcc ataaaatcca caaaagacaa agcatgacca tcgtaatagc tgctaacaac
    36541 agaccttcca aataaaagcg aaaaatttct actaacatct ttatctacct gattaccata
    36601 accttttttc atggcagctt agcttttaag cacatacaag aaaagcctag cctacctaga
    36661 cctttttatt atatcaaaag ccggctttta aatatacgtt tttgcatagt ttgcaaaaaa
    36721 ttcctttgtt cttgcttcct tagggtgtct aaagatctgc tcaggagctc cctcttcaag
    36781 aattttcccc ttgtctaaaa aaagcaccct atctgcaacc tgataaacaa aagccatatc
    36841 atgactcact aaaatcatcg tttgacctgc cttggcagca tcaataatag accgttcaac
    36901 ctctccaacc agctcaggat ccaaggctga ggtaggctca tctaataata gcacatctgg
    36961 cttcatggct aaagcacgcg caatagcaac cctttgcttt tgaccgccag ataaatgacg
    37021 agggtaatgg ttttcacgat cagacaagcc aaccttagct aattctgctc tagctatgtc
    37081 tgttgcttct tggtcagaca gttttttaac tatttttaat ccttccttga cattgtcaag
    37141 cgctgtgcgg cgttcaaaga ggttaaattg ctgaaagacc atcgctaatt ttcgtctaag
    37201 cgttagaatg tcttcttttg tgatgtgttc aaagtcaact gcaaagtcat caatcgtaat
    37261 acttcctgta tctggctgtt caagataatt catgcttcta aggaaggttg attttcctgc
    37321 acctgatgca ccaaccagag ctataacctg ccctttttca atcgtcaccg ttaaatcgtc
    37381 taagatcttt tgtccagaga aggacttggt taaatgagtt accttaatca ttagcgcaat
    37441 tctcctatct tgctattatt tgttgggatt ggtgctttga tagccatgtt atattcaatt
    37501 aggcgaccag cctgttctat caaaatacta atgccccaat aaactaaggc aactgagatg
    37561 taacgttcaa aataacgata atctgctccc cctagaatct gtgcctgtgc aaacatttca
    37621 acgatacctg cattgaaggc cagagaggtt ccctttgtca ggcctatcaa cccattaatc
    37681 aaggtcggtg ttgccacaac agcggcattt ggaatgataa ctcggcgata aacctgagca
    37741 gaggtcattc ctaggctctt agcagcctca atttcgcctg tgtgaacaga ttgaatcgca
    37801 gctctaatgg tttcactcgt ataagcagct tcattgaagg caaaggcggt aatcgcaaag
    37861 atagaagccg gaatagcgtt gatattccaa tcaaagccat agcgttgatt taagaatttc
    37921 agaaaaagag gaataccata gtagctcagc attagctgaa ccaatatggg ggttccacgc
    37981 aaaaagctaa caaaaaccgc ttgaatcgga taaagaatgc gaaccctgtt gattttgaca
    38041 atggcaaaaa ccaaggccaa aaaaagaccc aaggcagcac cagctatcgt caaaccaagt
    38101 gtgattggca gacgcctgat aatatctgga atggcatcaa aaacagcatg ccagctaaac
    38161 agcttccctt ctgggatcaa cgagatgagc ttgtcatacc aagcccaccc acttgttaaa
    38221 aacgtagatg tcatgtatcg cccctttata ctggtttgtc tcaatatttt cattttaaca
    38281 ttcttgagat gtcatgtaaa atagtaaatc cgcatgataa tgataagaaa agcctatcgc
    38341 agaggatagg actcaaacaa aggaaaaaaa ctctttgaaa taccgttaac agtagcctct
    38401 tggagctacc aagcttgaac ttgagccgaa ctctcaaagc ctccaagtgg ctaattctca
    38461 aagaatatag ccactggtac aagactaaca atcagctact aggccaaaaa ggtcaaaagc
    38521 ttggctagct ggcacagcta actgcctcaa aggctaggtc aacgaaagat tgaagcctgc
    38581 ccagggcttg agggctttta gccctgtcaa ttaattgacc ttggagataa agtctcctcc
    38641 caaaaatgct tggctgagct ttctgagctg acctgatttt ttaagcttag ccagcctttt
    38701 gttgacaaag ctctgtagag ccttaccctt ttgatcattg gcaaacacat aatattccaa
    38761 gccatcctta gcagtatcag cctgctcctt gagctttgtc acatgcacat caaagccttg
    38821 ctcctcagct acggttgtta gagaaatagc gtcatagaaa agaaagtcca gttgaccatt
    38881 ctccagcagc tgcagccttt gagtaaatgg ggttgactca gaagcatagg taaggtgaat
    38941 aggcttttgg tcaggatggg attggttcca tttttcaagg ataagcatgt aattggagcc
    39001 agctattcct tgggttttct ttccagaaag atcagctaag cttttatact gctgcttacc
    39061 ctttgttgcc agagcataat gcgaggccga aatagggctt gaaaacaaat acttttcagc
    39121 tctttcctta ctatagccaa aattattggc cccaatctga taacgacctg catcaatacc
    39181 agccaggatc gatggaaaag gaaccacctc tatgcttaac cgatactttt tggagccttt
    39241 aaaaaccctt tttagaacct caatatcata gcctgtaacg ctatgcttct tcctataggt
    39301 aaagggctta gtggcagcat ctgttgctac tctgatcacc tctttttgac gagctgtgac
    39361 ctcatggcta gtcacgactg ccaagagtcc tagacttgct agcaaaaaaa agagtgctcg
    39421 ctgtaattgt tttgtcatac catactccta tctcttatac agtagccatt ttaacaaaaa
    39481 atgataaatt tgaataatat catttctcta tcaaggcaat aagaaaatag tatcaaacaa
    39541 gcaattaaaa cagcacattc ttcatttacc tgatcatgga ttaaccacaa cagacaagct
    39601 ttagctatta gcaggctgcc taagccaaaa tcaacacctc aagctttcaa ctgactgatg
    39661 taaaagctag tagtcacctc tacaagaaga aaaagaactg tttgtgtcat tcaaccagta
    39721 gcacccttct taactggtca ttcctatcca gctctactac taggctgtca gttaacgatc
    39781 agaaaaaaag ttgacctatc tgccttatga agcctagaaa actagctttc attctgttta
    39841 acattagaaa acgagtaaat agtttaaaat aaatttttat tattaaactt taactgttgc
    39901 tatattaatc tttttacatt ataattaagt ataaggaggt tttctatgaa aaaggcaata
    39961 gtatcggtta ctttgttaac agtagctgtt ttaagcttat caacaagatt tatctactcc
    40021 actgattatt ctgatttaaa tcataaggag atggcacgtc ttatccagtc aagaaaacaa
    40081 ccagtaatta agtatcatga caatgtaacc attaataaaa tgattactta cctagctcag
    40141 gctaaaagag aaggcattct gacagagacc ttcctcatga attatatttt cgctggagag
    40201 ggtgagtacc tgactaaaaa ttcaaggatt attgccgatc ctgacggagg gtattggagt
    40261 atcctagaag gttatgaggg agatggcggt gttaagactg gtattgacgg cgtctcagag
    40321 ctcaatatct ttagtccaga atctaccagc atcggagagc ttcaagaagc ggtgctagcc
    40381 tggtatgagg ctaataagta accgcagctt agttaaccga ctgcttcata taatagctaa
    40441 tattagctaa tcataggcct tataggcatt gaaatggtca gacccatgct caatgcttat
    40501 aaggtttttt agtgcttacc atctaaccaa aaccatagcc ttcagagaga cattgagctg
    40561 aacaagcaaa aaagaggagc aagctcctcc tcaaacatta atacacctta atctacactc
    40621 ccacagagga agtaatttaa ggctggtgtg tcaaagcgta tcaacccgtt aatttcaatc
    40681 actattctga cagccaaagg tgcggcttta gttgttaata gctggtttta gttgccacgc
    40741 ttcaaagata gttgctgtaa caattgaagt aggttcgaca atttcaaatg taacaatact
    40801 tttatcacac cttttgcggg agcgtagatt gaaatccttg cacgcaacga caggaccatt
    40861 tgacatggga cactgaacag agttgaagcc tttaaaaaca atccctaaac agctttggga
    40921 cctaatcaca gttccttgac tcagctctgt caaggattct gttcatatca gcttagaatg
    40981 atcgctaaaa actttttgat ctaatttttc ttgaacggat gatctttacc aagcacctgt
    41041 cttaaaagct ttgctttctg gactgacgct ctgctcgtcc cttggcacgt ttttctgctc
    41101 gtcgctgctt gcgccgcttt tcatcaactg cccattgaat tttcttttta tagcccggtt
    41161 taattttttt cttttttttc ttaaccaggc caatcatttc agtgtctaat ttctgataag
    41221 ctttttcacg attctggcga cgatcacgat cgtaagtatc ctgaaactca ccatttttta
    41281 aaacctttgg tataaaggta atgcctagct tttccagctc cttgatatca gaatcatcac
    41341 ttggctgata aaaggtaatg gctgtccctg gcaggccgtt tctacctgtc cgccccacac
    41401 gatgcacaaa aaaggatagg tcttgaggaa tggcgtcgtt aatcacatga ctaaccccct
    41461 caatatcaat accacgcgcc gccaaatccg ttgccacaat gtattcaaat gccaggtttt
    41521 tgacttgatt catgatacgc ttgcgctctc taggaggaat acctccatga agcttggctg
    41581 ccttcatacc attagctgct aaaaaggcat gtaagtcatc agctctctcc ttggtattga
    41641 caaaaagcat ggccagataa ggctggatag cctttagagt cgccaaaatt tgctcatttt
    41701 tatcgcgtcc cttggttgat aacagccagt tgtcaatcgt atctgcaata acggtttctg
    41761 tcttgatctg ttcaatgaca ggattggtca aatacttcct taaaaagggc tgtagctttt
    41821 gtggaatggt tgctgaaaat acaagtattt ggatagtctt tggcagtgct gaagcaatct
    41881 tatccacagt gcttaaaaag cccatatcca ttgtcatatc agcctcatca acaacaaagg
    41941 tagaggcctt atgaatggct aaatctcctg acttgactag atcatagata cgacctggcg
    42001 ttccaatgac aagctggggc tgactaagct ttaacttgtc aagctgacgc tgcttgtctg
    42061 tccctccaac gtaattagca atacgaatct cctgcttaga atgcttagca atttgcctgc
    42121 tggcctcaaa aatctgtgtt gctagttccc ggctaggtgc tgtaatcaca gcttgaacct
    42181 cttctttttc ctccttgagc ttttcaaaaa taggcagcaa aaaggtatgc gtctttcctg
    42241 agcctgtctt tgactcaccc actaagtctc gtcctgtact gacaatcggg ataagacgct
    42301 gctgaacctc tgttggctct acaaagccaa gctcatctag ggcctcttga atataatgct
    42361 taaagtgata atcgtgaaat gacattattt acctcgtttt ctttctgata atactattag
    42421 tgcttgagat gagcaaaagg cggtgcctca agcactgccc cagccgctta caaataaaga
    42481 atcgctaaaa caatgagact ggctacaaga ccaagagccc ataggaaggc atcaaccttc
    42541 cattcagacc acttggctgc tttaccggac aagccgccta attccagatg atgatgaaaa
    42601 ggagtcatcc taaaaatccg acggccttca ccatattttt tcttggtgta tttaaagtaa
    42661 gtaacctgaa gcatgactga gcttgtctca agaacataga caatcccaat aaccagcaag
    42721 gtccattcct gacgaagcgc aatagaaatc gctgctagca ttgctcctaa ggctaagctt
    42781 ccaacatcac ccataaaaat tttggccggc ttatggttaa acaagaaaaa ggccagcaag
    42841 gcaccaacca tgatacctat caagagcaaa acatcaaatt gtccctgagc ataagcgata
    42901 acaccatagg ccagcaggct aatcacaaca gataccgagg ccagaccatc aataccgtct
    42961 gtcaggttga ccgcatttga aaagccaacc acccaaaaaa gaacaaagca taggtataaa
    43021 aagcccaaat gccaatgata accaaagaca ttaatcgcat caataccact tggcatgacg
    43081 tgtatcacat aaaagaccag gcctccaaca atctgaaacg tgaatttttg cttggcagta
    43141 aggccttcat taacctgctt gaagatcttt aagaaatcat ctaaaaagcc tatgatcccg
    43201 taaatcaata caatcaacaa gatccccgaa atcaagccta ggctttgtcc atctcgaaaa
    43261 tagactaaag caaacacaaa ggataagctt gtagcaacaa gaagaaaaac tgttcctccc
    43321 attgtaggtg ttccagcctt agccaaatgc tgcttaacgt cctcatgcat ctgctgcccc
    43381 ccaatttttt tcaactggta aagccttata aagtgaggca tggcaagggc agtcacagca
    43441 aaggctatca gacctgctag aatggttaaa aacatgttaa tctcctaaag ttatggtaat
    43501 ttttttgact tttttgagcg cttttccgac atcaacgctc tgtttaacga cacgtcccga
    43561 gcttgatccc ttgtacttga tatcaatgcc agtccattta gcaaaggtag ccacattagc
    43621 cttagtccag ccgtacatat caggcatctc atcaaaatga tttgataaaa tcagaagctg
    43681 ttggttagca gctagattgg tccctgcctt tttagatacc tttttaatct tgctgccatt
    43741 gccaaggaca atagggtgaa ccagatttct gcgtagctca tcagctgatt ttcctgtatc
    43801 ttggccaaca atatcaggca actgataagt agcctcgtga ctggtatcta cagcaaccgg
    43861 cttgtctaaa gtatccttca tcaaataggc ttcctctaaa acagggttga taatatcctg
    43921 ccaaaacacc attgcccaat gctctgggtg cttcagtgtg acatacatca gaaaatcagg
    43981 ctcatcagct ggcaccatag caaccaccga ataaatatag tttgtcaagc caccatctaa
    44041 ataacctgta ccgtccttag tcgcaatctg cgcagtccct gacttgacag caactggtaa
    44101 ttgaccaacc ttaaccactg gacctgatga tttcaaatga agggttccaa attgtgggtc
    44161 agtcccaacg ttaatcatgt attttcgtgt ttcactggca gccttttggg acaccggctt
    44221 tccgacaatc tccttgtctg acacccggta agtatctgta tttgggtcat aaatgcgact
    44281 aacaaattga ggctctagca tcacaccgtc attagagatg gctgtaaagg ctctaagcat
    44341 ttgaatttgc gtcaccgaaa tcccctgacc aaaagcgctc attgcttggg taacaatatt
    44401 atcagaaggg aaaatacctg ggtcttcatt ttccaagcca aagcgtgtcc ggaatccaaa
    44461 acggaattta gttaggtagt tcatccattt gtcatttccc attttttgct ctagcttggt
    44521 catgccaacg ttacttgaaa acgaaaagcc ttgagcatag gtcatgtact gccctgtaga
    44581 aatcccttcg ttaatcgccc aatcctgaat ggtagcatca gcaatggtta agccattcgc
    44641 attgctaaag gtctcatcag gattaaagac cttctcatca atagcagctg ccagagtcat
    44701 aaccttcatg gttgagccgg gctcaaactg cccctgatgg agaatatttt gccagctata
    44761 gcttttgctg tttagcccct ccaaggtgtc tgcattatag gttggtcttt gagtagtcgc
    44821 taagatttca ccagtcttag catttactag agtagcacta gcaagctctc cttgcgcctt
    44881 cgactgaaag acgtccattt gcgtttctag aaaggtttga ataggctctg acagggtggt
    44941 ataaacgtcc ttaccatcaa ctggcttttt cactgtcttt cctgttccaa gcagggtatt
    45001 accgtttcta tccttttgat aagtgatgat tccatcttcc ccagataaga tgctatcaaa
    45061 ggccgcctcc atgcccatct ttccaactag gctcttggta ccgtcctcct tgttttcctc
    45121 aagtgaagca agaccaatca gctctgaagc aaaggtccca tttggataca tacggctagg
    45181 acttgctgaa aatgcgatcc ccttgatttt agctgcctcc atagcctttt ggatcgttgt
    45241 catcgtgcta taagaaatac ctgagccaga cggaccaaag gaaacctgaa aaagaccttt
    45301 ttgcttaagc tgcttaataa cgtccttttc ctccataccc agctgctcct tgaggatttg
    45361 agcaaccttg tcatactgag acggttgaac aaaaagcttc tcgccagtcg ctgacacaaa
    45421 ggacttatca agaatggcat aaatgctata ggtcgtcgag tccacagcga tagctgtgcc
    45481 attgcgatca taaatcgtgc ctcgcttggc ctgaacagaa accgtctctt gataaacctt
    45541 tttggctcca tctgatagct taacaccgaa tttctgatcc gtcccgataa tgatcataaa
    45601 attaatcata aagatgaaga aaataaagat ggttaagagc atcatgtttt gccccaccct
    45661 caagcggttc tgaacaggtg tctttcgatc acgaaccaca taatctaaaa aatatctttg
    45721 ccattttgtc atagcttact cgaccttctt aatgttatca tttcggttac taagccctgc
    45781 tttgccagca atatcaacaa tgcggtcacg tcgcgacagc tcattaacct cttgcttggc
    45841 attgttaagc tctgtccttt tatctgagat ctgcctattg agctgagtga tatgctgctg
    45901 gagctgcaat ttacggcttt gcaggtaaat aatgcttaca gccatcgtta ctgctgtcag
    45961 gataagcgta gcataaaaag ccttctcaac cctcgagaaa gttctaattc ttttttgcaa
    46021 ggcttttgaa actgcctgag ttcttttttc attaaccata atctatttcc gaacttttct
    46081 tgcgactcgt agcttggctg aatgtgccct attgttagcc attagctcct tttgacttgg
    46141 taaaatcggc ttacgcgaaa ccaattcaag cttaggcttg agctcatcag gtataaaggg
    46201 aagtcccttt ggagcatcag ctgtgcttgc ttctttaaac aagtgctttg tcagacgatc
    46261 ctccaaagaa tgaaaggtaa tcactgagat acggccatca agggctagca gctctatcgc
    46321 ccgctggata gacgcatcag cagcaccaag ctcatcattg acctcaatac gaatagcctg
    46381 aaagatttgc ttggctgggt gtcctttttt cttgagctcc ttggctggct tagctgattt
    46441 gatcaatgct gccagctctg tggtggtgct gattggctta atggctctcg cctgctcaat
    46501 cttacgagca atctgctttg agaacttatc ctcaccatat ttaaaaaaga tccgaactaa
    46561 gtcattgaaa tcataggtat tgacaacctc ataggctgtc aaagccgcct ggctatccat
    46621 tcgcatgtcc aagggagcgt cctgcttgta agaaaagcca cgctctctct catctaactg
    46681 cggactagaa acccctaaat catacaaaat cccatcaatc tctgtaaccc catgctccag
    46741 caagcgtgcc ttaaggtgtc taaaattgtc cttaataaag gtcacctgtc ccttgtcaat
    46801 atagggcttg agctgctcct gcgcgtgatc aatagccttt tggtcctgat caaagcaata
    46861 caagtgcccc ttatcaccaa gcagagacag caaataagct gagtgcccag agccaccaag
    46921 ggtcgcatct acataaatac catctggctt aatatccagc atatcaacag cttcatgaag
    46981 aagtacagtt acatgatgaa attcgtttgt catagctcta attgtaccat acttcaaagg
    47041 gtttataaat caaaaagtaa gagaaaaggg ctttcaaggc ctaagaaagt ccctctttat
    47101 cttacttttt ttggcttagc tatccttgac atcaagatga ctaagagctt gctgcacagc
    47161 ctcatacagc agctcagccg attcgagcac ctgcttggtc tcctttaaca cccgaaaatc
    47221 tgtcaccgaa ttatctagcc aaatatcaaa gatcttatcc tgtcttgtat gagataagct
    47281 agaaggcaag cgcaactcac taaccttcag ctccttttga tacctacaga ccagatttct
    47341 cacgtcccct aggctctcat taatagcact gattttttgc ctttttaccc agcttgttag
    47401 tatcccattg tcgaacaaat caaaaaatcc ccacctctta agctctttca atgcctcaat
    47461 gacagactca agcttaaaag ctaatgtctt taggtctcgt atggtttctt gcttctttag
    47521 atcccttgtc ataagcctac ctccttagca gctagctccg aatctggcca tttccattga
    47581 tcaggtattt actgctggtc aaggcctcaa gtcccatcgg gccacgagca tgcatttttt
    47641 gtgtggaaat gccaatttct gctcctagac caaagacaaa gccatctgta aagcgtgtcg
    47701 aggcattcac ataaacagct gccgagtcaa ccagatcctg aaaacgctct gcagcattga
    47761 tattagctgt gatgatggct tctgaatgat gactggtata ctgattaatc caagaaatag
    47821 cttcatcaag agaggaaacc agatgaacag acatgatata atccaaaaat tcagccgcat
    47881 aatcttcctc tgtggctaat acagccttgc taaacaaggc ttttgcctgc tcatctgctc
    47941 gccattccac ctgctgaacc ttgctgatgg ctgcttcaag catgggaata aaggtcgctc
    48001 ctaccttctc atgaataatc aggctttctg cagcattgca gacgcttggt ctttgcgtct
    48061 tagcattaat cacaacctta acagccatct ctagatcggc tgcttcatca acataaatgt
    48121 gaacattgcc aacccccgtc tcaatgactg gcaccttagc cttttccttg accgtttgaa
    48181 ttaatctggc acccccacga ggaatcaaga catcaatata atccgttgcc tgcatcaatt
    48241 cctcagctac agcatgagag gtatcctcaa ccagcaaaac agcatctggc gtaatagctg
    48301 atgcctctaa ggcatttctg ataagcctga ccaaggccat attagagtag agagcatctt
    48361 tgccacctct aagaataatg gcattattgg tcttaaaggc caagctaaag gcgtcaacag
    48421 aaacattagg gcggctttca aaaatcatcg caataacacc taaaggcaca cgcttttggg
    48481 ttattttcag gccgtccaga tttgtatagc ccttaatcac ttcgccaatg ggatcagcca
    48541 agtctgccac ctgtctgacg ccctgagcca tcgcatggat acgatctgct gtcaggcgta
    48601 agcgatcgca cagaatctct gaaatcccat gctcagccgc cttagccaga tccttggcat
    48661 tttctgtcaa aatcatatcc gtctgggcca ctaattcctc agccaaaaag gcaagaaatt
    48721 gatttttatc cttcgttgtc aaggatacca aggccctact agctgcctta gccctttgtc
    48781 ctagctgttc tattgtcatc acgcgtcacc tctttctatc tgtttaaacc aagtgcctag
    48841 cttttctccc tccaagaccc ttaaaatgtc tctagggttg gcaccattca tcaaaatcat
    48901 ttgcccctga tgctcaaaca tcatctgggc tgattggatc ttacttagca taccaccagt
    48961 tccaaatctg ctgcctgcac cgcctgctga ggctataata tcctctgtaa tctctgtcac
    49021 atgactcctc aagcgcgcgt cctcatagat ggttggattc ttatcaaaca aaccatcaat
    49081 gtctgatagc ataatcagca aatcagccct tgtaatacga gctacgatag ctgataagcg
    49141 gtcattgtct ccaaattttg ttgaatgatc catctcatca acactaacag catcattttc
    49201 gttgacaatg gggacaatcc ctaaactaat caggctttca aaggcattgg tgacatttgc
    49261 cagactttct ggaaaaacaa ccacatcacg tgtcagcaaa atctgagaca ctgtcgtctg
    49321 atagtgggca aaaatttgcg aataaaggct catcatagca acctgcccca cacttgaaac
    49381 agcctgctgc ttggcaagct gacttggtct tttggccatt ttcaacaggt caagcccaaa
    49441 gcccatggcg ccagaggaaa ccaaaataac ctcttttccc ttattcatta agcttgaaat
    49501 cacaaaggct aaatggtcga tcttttctaa gttaatcttc ccattagcaa gcaccagcga
    49561 gctggttcca attttaatta caatacgctt tacatcttca aattgtcgtt tcatcatatt
    49621 aggattatag cataaaaaac agcccagagg actgttagat tgaagccaaa atcaatcagc
    49681 ctatcagctt gataaaaaaa aggatcactg gctacccatt cacctaagat ataaaaatcc
    49741 acctgatagc cactccaagc aggatttcct ttgtgacacc acataccacg ctacgcttta
    49801 tcctattgta agtttaagtc tgatcctcct gcattgtcct gtcattttta atgaccatat
    49861 accaacacta aagctattga caaaaacgca caatacgata aaatgaaagc gcaaacagct
    49921 atatttacta cctaagggcc agaccttgct gtaaagcgca atacctgaca gaaagaacac
    49981 gtttcagaag tagcaagaac aagtcacagg catactgtct ggcacattgg cgcaaaggct
    50041 accagtgttc aacaagactg gaacgcaaat caataggctg gaaatcaagt aggaaaaccg
    50101 tatcatttaa atttttggaa tcccaagact caattgttct caattagttt gggggcttag
    50161 gacgacagag cctgtcagtc atctaaagca attaattagt tataggaata aatcactatg
    50221 gttaaactat caaaaagaag caagatagct atgtcatttt taattgtctt ttgtggtata
    50281 tttttcgtcg ctcaaaaacg attcggttca tcagaccaat catttaccgt aaggccagac
    50341 gcagatttct atatagtcgg ttaccacaat attgaaggtt atcaattgac aaatgagcag
    50401 ccgcaaaaaa tttctgacgc taagctcgaa gtggtcaaag gtcagatcaa tcaagtggtt
    50461 aaacgagcag agctttcaaa tcgttatctg gtcttttccg aggaggggcc acctttgggg
    50521 gcaataggaa gacttatcgc tcttgatttt caaaaaggca acgtgacgta tcacccaaca
    50581 gctgattatg cctttacttc ctccggagta tcaccagatt attatttcac ttctacagca
    50641 a
//
LOCUS       DARYLJ010000010        48181 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYLJ010000010 DARYLJ010000000
VERSION     DARYLJ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48181
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TU746_000517"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TU746_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL0890893.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TU746_000518"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TU746_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TU746_000519"
     CDS             1286..2599
                     /locus_tag="TU746_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0890894.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGCNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TU746_000520"
     CDS             2700..3587
                     /locus_tag="TU746_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0890895.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TU746_000521"
     CDS             3600..4430
                     /locus_tag="TU746_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL0890896.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TU746_000522"
     CDS             4446..4901
                     /locus_tag="TU746_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL0890897.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TU746_000523"
     CDS             4926..5576
                     /locus_tag="TU746_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL0890898.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TU746_000524"
     CDS             5605..6525
                     /locus_tag="TU746_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL0890899.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TU746_000525"
                     /pseudo
     CDS             6540..7424
                     /locus_tag="TU746_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            7424..7696
                     /locus_tag="TU746_000526"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TU746_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TU746_000527"
     CDS             complement(7738..8562)
                     /locus_tag="TU746_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL0890900.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TU746_000528"
     CDS             8791..9564
                     /locus_tag="TU746_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL0890901.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TU746_000529"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TU746_000529"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL0890902.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TU746_000530"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TU746_000530"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL0890903.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TU746_000531"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TU746_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL0890904.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TU746_000532"
     CDS             12390..13052
                     /locus_tag="TU746_000532"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL0890905.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TU746_000533"
     CDS             13045..13677
                     /locus_tag="TU746_000533"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL0890906.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TU746_000534"
     CDS             13679..14950
                     /locus_tag="TU746_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL0890907.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TU746_000535"
     CDS             14940..15878
                     /locus_tag="TU746_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL0890908.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TU746_000536"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TU746_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL0890909.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TU746_000537"
     CDS             16830..19334
                     /locus_tag="TU746_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL0890910.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TU746_000538"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TU746_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL0890911.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TU746_000539"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TU746_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL0890912.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TU746_000540"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TU746_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL0890913.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TU746_000541"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TU746_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL0890914.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAHL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TU746_000542"
     CDS             24977..25831
                     /locus_tag="TU746_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL0890915.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TU746_000543"
     CDS             26041..27237
                     /locus_tag="TU746_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL0890916.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TU746_000544"
     CDS             27660..28181
                     /locus_tag="TU746_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL0890917.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TU746_000545"
     CDS             28257..28628
                     /locus_tag="TU746_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0890918.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TU746_000546"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TU746_000546"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL0890919.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            30244..31902
                     /locus_tag="TU746_000547"
     CDS             30244..31902
                     /locus_tag="TU746_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0890920.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            32071..32985
                     /locus_tag="TU746_000548"
     CDS             32071..32985
                     /locus_tag="TU746_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890921.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            32995..34026
                     /locus_tag="TU746_000549"
     CDS             32995..34026
                     /locus_tag="TU746_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0890922.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            34038..35084
                     /locus_tag="TU746_000550"
     CDS             34038..35084
                     /locus_tag="TU746_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890923.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            35084..36019
                     /locus_tag="TU746_000551"
     CDS             35084..36019
                     /locus_tag="TU746_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0890924.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(36648..38330)
                     /locus_tag="TU746_000552"
     CDS             complement(36648..38330)
                     /locus_tag="TU746_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL0890925.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(38332..38562)
                     /locus_tag="TU746_000553"
     CDS             complement(38332..38562)
                     /locus_tag="TU746_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL0890926.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            38848..39546
                     /gene="tsaB"
                     /locus_tag="TU746_000554"
     CDS             38848..39546
                     /gene="tsaB"
                     /locus_tag="TU746_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL0890927.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            39549..39974
                     /gene="rimI"
                     /locus_tag="TU746_000555"
     CDS             39549..39974
                     /gene="rimI"
                     /locus_tag="TU746_000555"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL0890928.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            39964..40980
                     /gene="tsaD"
                     /locus_tag="TU746_000556"
     CDS             39964..40980
                     /gene="tsaD"
                     /locus_tag="TU746_000556"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL0890929.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            41002..42030
                     /locus_tag="TU746_000557"
     CDS             41002..42030
                     /locus_tag="TU746_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL0890930.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TU746_000558"
     CDS             complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TU746_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL0890931.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(42888..44060)
                     /locus_tag="TU746_000559"
     CDS             complement(42888..44060)
                     /locus_tag="TU746_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL0890932.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            44186..44716
                     /locus_tag="TU746_000560"
     CDS             44186..44716
                     /locus_tag="TU746_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL0890933.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            44761..45348
                     /locus_tag="TU746_000561"
     CDS             44761..45348
                     /locus_tag="TU746_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL0890934.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            45452..46174
                     /locus_tag="TU746_000562"
     CDS             45452..46174
                     /locus_tag="TU746_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0890935.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(46216..46515)
                     /locus_tag="TU746_000563"
     CDS             complement(46216..46515)
                     /locus_tag="TU746_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL0890936.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            46913..47500
                     /locus_tag="TU746_000564"
     CDS             46913..47500
                     /locus_tag="TU746_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890937.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            47639..>48181
                     /locus_tag="TU746_000565"
     CDS             47639..>48181
                     /locus_tag="TU746_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0890938.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT        13642 a         9419 c        11268 g        13852 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct gcaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctt
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcaca tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctaca aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gctatgagga cagaagtgtc
    30121 tggtttatct atttataaaa ataaaatcaa aaattttcag ataaatctat ttcctttttt
    30181 cagaattatg gtataatcta atttaattat tttaaataac tattttgtta ggaggaaggt
    30241 tatatgacag tactaggaac aaaagcatgt aagcgtctgg gcttagcggc agttacgcta
    30301 gcctctgttg ctgccttgat ggcttgtgga aataagcaat cagcgtcaac agacaaaaag
    30361 agtgagatta attggtatac gccaactgag atcatcacac ttgatatctc aaaaaataca
    30421 gatacctatt ctgctttggc tattggtaat tctggcagta accttttgcg tgctgatgct
    30481 aaggggaaat tacagcctga tttggctgaa aaggttgatg tgtcagagga cggcttgacc
    30541 tatacagcaa ccctgcgaga tggcttgaaa tggtctgatg gtagtgatct aacagcagag
    30601 gactttgtgt acagctggca gcgaatggtc gatcctaaga cagcctcaga gtacgcttac
    30661 ttggcaactg agtcacatct gaaaaacgca gaggacatta atagcgggaa aaatcctgat
    30721 ctagactctc taggggtaaa ggctgatggg aataaggtta tttttacctt aacggagcca
    30781 gcaccacaat ttaagagctt gctgtccttc tctaactttg ttcctcaaaa agaatccttt
    30841 gtcaaggacg ctggcaagga ctatgggaca acatcagaaa aacaaattta ttctggtcct
    30901 tatattgtca aggactggaa tggcactagc ggaaccttta agctagtaaa gaataaaaac
    30961 tattgggacg ccaaaaacgt caaaactgag acagttaatg ttcaaacggt taaaaagcca
    31021 gatacagctg ttcaaatgta caagcaaggt aagctagact ttgcaaatat ttctggtacc
    31081 tcagctattt acaatgctaa taaaaagcat aaggacgttg ttccggttct tgaggcaaca
    31141 acagcctata tcgtatataa ccagacagga gctattgaag gcttgaacag tcttaaaatt
    31201 cgtcaagcct tgaatttggc aacagaccgt aagggaattg tatctgcggc tgttgataca
    31261 ggctcaaagc cggctacagc gctggttcct acaggtcttg ctaaattatc tgacggaaca
    31321 gatctaacag agcatgtggc acctggctat aaatacgatg acaaggaagc tgcaaagctc
    31381 ttcaaggaag gcttggcaga gctgggcaag gatgccttga caatcaccat cacagctgat
    31441 gctgatgcgc cggctgccaa gtctgcagtg gattacatca aggaaacctg ggaaacagct
    31501 cttcctggct tgaccgttga agagaaattt gttcctttca agcaacgtct tgaggatact
    31561 aaaaaccaaa actttgaggt tgcagttgtt ctttggggtg gtgattatcc aaaagggtct
    31621 accttctatg gcttgtttaa atcagggtct gcttataact atggtaaatt tacgaatgca
    31681 gactatgatg cggcctacaa caaggctcta acaacagatg ccttgaatac agatgcggct
    31741 gctgatgatt ataaggcggc agaaaaagcc ctttatgaca atgcccttta caatcccctt
    31801 tacttccgta gcggtgaagg cctgcaaaat ccaagcatca aaggtcttat ccgtaattca
    31861 actggtctaa atgttgactt tacttacgct tataaggact agcaataata ttattgtaag
    31921 cctatactga cctagcaagg ccacagctcc ttgatgggaa gtgtttaaga gaagcttagg
    31981 gctagctagg agtgtctatc ctgtaggcct tggcaagcat attgcaagaa ttggtcttaa
    32041 ccagttcttg cttttggtta gaggaaaaat atgattaaat atcttttgaa gcgagtggct
    32101 attttagtag tgacactctg ggtggtgatt accctgtcct tctttttgat gcaggtgatg
    32161 cctggaacac cctataacag tcctaaatta actgatgaca tgattgctat gctgaatcag
    32221 cagtacggct tagataagcc tctttggcag caatatttga agtatttgtt tgatattctt
    32281 catggtgact ttggcaccag ctatcagtcg attaatcaat cagtgacaac cctgatctcg
    32341 cagcgtctgg gggtatctgt gcacttagga gtacaggcgc ttattgttgg tattagctct
    32401 ggcttagctg ttggtgctgt ctcagcgcgg aataaaaata atagcattga tgccatttta
    32461 agtgttatct caacgcttgg tatttccatg ccgtccttta tcattggctt gctgctgctg
    32521 gattatttgg gctttaaatg gaatttactt cccttgtctg gctggggaag ctttgggcaa
    32581 acgattttgc cgacgcttgc tttagctatt ccggtctttg ctcaggtgac ccgttttttc
    32641 cgcagcgaga tgatcgagac cttatcgaca gattatattc agctagctag ggcgaagggc
    32701 ttgactaagc gtcaggtgac tcgtcggcat gcttaccgca attcgatgat tcctgtgtta
    32761 accttggttg gtccgatggc tgctggtatt ttgacgggat cagccctgat tgagcagatt
    32821 ttttccattc cggggattgg gcagcagttt gtgacctcta ttcccaccaa ggattaccca
    32881 gtgattatgg gaacaacgat tgtctatgcg ctaatgctga tggttgctat tttggcaact
    32941 gatatgatca ttagtatcgc agatccacgt gttcgtttgg gataggagag tgctatgcta
    33001 gaagaaacaa aatcatttaa gcttgttgga gcaggtagct tagcgacaca agaaaaaatt
    33061 gaaaagccgg cgctttcctt tcttcaggac gcttggcgta ggctaaagca caataaacta
    33121 gctgttattg cgatggggtt tttagctgtg ctgcttttgt tttctattgg ttctttattt
    33181 gttgtatcta cagatgatgc caatagcttt aacagtaagg aggtaagcat ataccgtaac
    33241 ctgccgccaa agctaagcag cagcttgcca ttttggaatg ggaccattac ctacgctggt
    33301 aatacagagc ccaatgacgc ttatgcggat caaggggtcc cagaggacaa ggccttctta
    33361 ctcgggacgg ataatctggg gcgcagtatt ggaaaacgta ttacggtagg gattcgtatt
    33421 tctcttttga ttgctattgt cgcaaccctg atcgatctag tgattggggt aacctatggc
    33481 ttggtctcag gctttgttgg tggcaagact gacatggtga tgcagcggat cattgagatt
    33541 atctcctcta ttccaaacct tgttattgtg accatgcttg gtcttttgct tggcaatggt
    33601 gtgacttcaa ttattatttc aattgcgatt gtaggctgga cctcaatggc taggcaggtc
    33661 cgcaacctaa ccctgtctta tcgagagcgt gatttcgtcc ttgcttctcg tgccttggga
    33721 gaaagtaata tcaggattgc ctttaagcat gtattgccaa atatttcagg gattattatt
    33781 gttcaaatca tgatgactgt tccgagtgct atcatgtatg agtcagtttt atctgcgatt
    33841 aatttaggcg ttaagccacc gacagcttcg attggttcat tgattactga tgcacaagaa
    33901 agcctgcaat attatcctta tcaggtgctg ctgccggctt ttgccttggt gttaatttcg
    33961 ctagccttta ttttgttggg tgatggcttg cgtgacgctt ttgatccaaa atcaagtgat
    34021 gaataggggg aaataaaatg acgaatgaaa ccattttaag tgtcaaaaac ctccatgttg
    34081 attttaaaac ctacgctgga gatgttaagg cgattcgtga tatcagcttt gagctaaaaa
    34141 agggagagac tcttgcgatt gtgggagaat caggctcagg gaaatctgta accactcgca
    34201 cgctgatggg gttaaatgct aagaatgcaa gtatttcagg gaatatttgc tttaagggca
    34261 agcagctcaa tgagctgaag gaggaggaat gggtcaaggt gcgtggcaat gaaattgcaa
    34321 tgatcttcca ggatccgatg accagccttg atcctaccat gacaattggc atgcagattg
    34381 cagaggcaat aatgattcat caaagcattc ataagacaga agccttgaag cgtgctttag
    34441 acctgatgcg tcaggttggt atcccaaatg ctgaggagca ccttaaggat tacccacatc
    34501 agtggtctgg gggcatgcgg caacgggctg ttattgccat tgctctagct gccaatcctg
    34561 atattttgat tgcagatgag ccgacaacag ctcttgatgt taccattcag gcccagattt
    34621 tgaagctgat gaaggatatt cagtctcaga ccgcatcatc gattatcttt attacgcatg
    34681 accttggtgt tgttgctgga atggtagatc gcgttgctgt catgtatgct ggaaagattg
    34741 tcgaatatgg aacggttgac gaggtatttt atcatccgca gcacccttat acctggggct
    34801 tgctcaattc gatgccaaca acagctactg cagcaggtag cttgaggtct attcccggaa
    34861 cgccgccaga tttattaaac cctccaaagg gagatgcttt tgctgcccgt aatgagtttg
    34921 ccctagacat tgaccatatc aaagagcctc caatgttcaa ggtaagtgac agccactacg
    34981 cagcaacctg gttgctagat gagcgtgctc ctaaaataac ccctccattc ccaatccgca
    35041 agcgttgggc aaaatggcag gaaatggaag agaggaaggc ttaatgacag aagctcgtaa
    35101 aaaattaatc gaagtaaaga atgtttcctt aacctttaac aaggggaaga aaaacgaggt
    35161 taaggctatt gatcgcctta gctttgacat ttatgagggg gaagtatttg gccttgttgg
    35221 ggaatcaggc tcaggcaaga cgacagttgg tcgagctatt ttgaaactgt atgacattag
    35281 tgatggtgag attatcttta acggagaaaa tgtctcccaa ttaaaaggga aaaagctgca
    35341 tagctttcgt aagcatgcac aaatgatctt ccaagatcct caggctagtt tgaacggccg
    35401 tatgaaaatt agagacattg ttgcagaggg cttagacatt catggcttga cagcctcaaa
    35461 ggcagagcgt gaagcaagag tccaggagct gttaaagctt gttgggctca atcagaacca
    35521 tttgacgcgc tacccacatg aattttccgg tggtcaacgc cagcgaattg gcattgcgcg
    35581 tgccttggct gtgaagccga cctttattat cgcagatgag ccgatttcag cgcttgatgt
    35641 gtcgattcaa gcacaggtag tgagtctcat gcagcaattg caaaaaaagc gtggcttgac
    35701 ctatctcttt atcgctcacg atttgtctat ggtcaaatac atttcagacc gtattggtgt
    35761 gatgcattgg ggcaaaatgc ttgagattgg gacatctgat gaggtttaca atcacccgat
    35821 tcacccttat acgaaaagct tgatctcggc cattcctgag ccggatcctg aaaaggagcg
    35881 taagcgtatt gcagaggttt atgatcctag ccaggagcta gatggccaag agcgacaaat
    35941 gcatgaaatc actcctgggc attttgtctt agcgactcag gccgaagccg agcagtaccg
    36001 agcagagtgt ggcctttaag agactagcat aacagcaatt tcctaaaaag gctgatgtga
    36061 tagtttttta ggtatgacag accaaaagtc gtatgacctt tgccgatcaa aagcaggtgc
    36121 catgcgattt tggtggtatg gtggagcttt gtcagccaac ctagactgca caaaaagctc
    36181 cttatgatag aatttgtagc atgaggttgc gacacaagtc taccctaaaa taaaacaaaa
    36241 taaaacaacc gaacaggtct agctttctga gatttcaaaa gccagacctg ttcggttttt
    36301 aatgaatgag actaggtcat aaagtatctt agttaagatt gtctaaagtg cagctctttt
    36361 tgctgtgctt gctgctgttt ttataaaatg actcgtggga atcaatcagc ctgtagtcaa
    36421 atgttatcgc tctctttttg agatgtggct tgacaggttt gctaagctca gcaggctatt
    36481 tttagtagta tagctagaca aaggccctta agctagctca gcacgtcact ctgttaagct
    36541 tagctaacag cacgtgttgg gcaagtagta tgcctcatag ccttgtacgt cagtcattga
    36601 cgttgacgca acaaaaaaac acgagtctct aagctcgtgt caaagatcta ttggctatca
    36661 ggcgttagaa ccatcggaat gataataggc tcgcgctctg tcttttcgta aaggaaggga
    36721 cgaagcgcat taacgatagc accattgaca gactggatac tagcgtcctt atttttcaga
    36781 gcgatacgaa tcgcattgaa aagcacgcgc tgactctctc tgatgagctc gcctgactcg
    36841 cgcatgtaga taaagccgcg gctgagaata tctggtccgg ctaagatcat ctgtgtctca
    36901 aaatcaacag tcgccactgc aaggacaacc ccgtcctctg aaagatcacg acgatcgcga
    36961 aggactgctg tcccaatatc tccaatgcca ttgccatcta cataaatgtc ctgagcattg
    37021 aaatgaccgg ctatacgagc gctatcactg gtcaaggcca atacgtcacc attttccatg
    37081 ataaagatat tttcctctgg aatcccaata tcaacagcaa gcccagcatg aaccttctgc
    37141 atacggtatt caccatggac aggcataaag tattttggct taataaggct aagcattagc
    37201 ttttgctcct gctggccacc atgaccggag gtgtggatat tgttgacctt tccatgaata
    37261 acgtcaactc cagcctcctg aatcgtattg attagcttat tgacgctgac ggtattacca
    37321 ggaattggac ttgatgaaaa gatgacagtg tctccaggct gtaagctgac ctgtctgtgg
    37381 gtaccattgg caatcctagc aagggcggcc atagactccc cttgactgcc ggtacacatg
    37441 atcaaaatct cactagcgtg gtaatgttta atctcattag gctcaataaa ggttcccttt
    37501 gggaccttga tgtagccaag ctcaataccg ttaacaatag ccttttccat tgaacgacca
    37561 aatacagcaa tcttacgccc tgtcttaaca gcggcttctg cagcctgctg caagcggtag
    37621 atatttgaag caaaggaagc aaaaatgata cgtccatgaa tgccttcaat aatgttcatg
    37681 attgactggc caacgacctt ttcagaattc gtaaaggttg gtatctcggc atttgtcgaa
    37741 tcggacaata gacaaagaac cccgtcctta ccaagagcag ccatgcgatg tagatcagcc
    37801 ggatcaccaa caggtgtaaa gtcaaacttg aagtcgccag tacagatgac tttcccttgt
    37861 ggggtgtgga taacaatccc aagtggctct ggaatagagt gagttgtttt aaagaaggta
    37921 acgctcatat gcttaaaggt gagctcggta ttgtgattaa tctcatagag cacagcatcg
    37981 cgtaagagac cgtgctcctc cagctttcct cggataagag ctagagctaa ggggcctgca
    38041 tatataggca cattagcttg ctttagtaaa aaaggaatac cgccaatatg atcctcatga
    38101 ccatgagtaa tcacaagagc cttgacgcgc tccaaattgt caacaatata agagtaatcg
    38161 gggataacat agtcaatccc tagcagatcg tcctctggga atttgatacc ggcatcgaca
    38221 atgatgattt catcttgata ctcaataccg taggtgtttt tgccgatctc tcccagacca
    38281 ccaatcgcat aaaccccaac ctcattaggc cttaaactga tatttgtcat gttaaaactc
    38341 cgttaatgtg aaaacaccag tttctttttc gtagtctagg tgcttgtctg agagcagctc
    38401 gatgaattcg acattgtaat cggtgtgctc ttcaaccatc ttgcgggctt tgatacgccc
    38461 ctcaagctca cttgcagcgt ctatatctag gtatagggcc tgtgtgtttt cacgacgcgg
    38521 actgcgttcc tttgtttctt ggtagaaaac tttataaatc attgatgata tcttcctttc
    38581 atgatgaatc gattatccaa acaataacaa ataggtcaaa acgagaaggc ctctgttttg
    38641 acgattacct atcatgtgat tattgtgtaa tagatttaaa cctgattctg tgcaattact
    38701 aagattatac catactatcg gcttttagta aaaagtttcg ataaaattat tctcttgacc
    38761 ggtgatgagg ctgtggctgt ctccttttcc atgaccttta ttttatgtta taattgtgga
    38821 atagaaatga cttgagaagg gcttagtatg aagacacttg catttgacac atcaaataag
    38881 gcattatctg ttgctctatt agacgatggc acattattgg ctgatcttac gattaatgtt
    38941 aagaagaatc acagtattag tctgatgccg gctattgatt ttttaatgtc ctcagctgac
    39001 ctgaagccaa aggatcttga tcggatcgta gtagcagaag ggccgggctc ctatactggc
    39061 ttgcgtgttg ctactgctac agcaaaaatg cttgcttata gcctaagtat tgacctcgtt
    39121 ggcgtatcaa gcctatatgc cctagcggct tctacttgcc gagaaaaccc tgatagcttg
    39181 gttgtccctt tgattgatgc tagacgacgc catgtttatg tgggctatta tcaccatcaa
    39241 aaagctgtga aacaggataa gtacgcgtcc tttgatgctg ttttagcaga actggtctct
    39301 tgtgaccatg tgatttttgt tggagaagtg gagggctttg cagaggacat tcgatcagcc
    39361 ttgccagagg ccaagataaa gccaagtctg ccatcggctt ttgaggttgg tttgctaggc
    39421 agcagccttt cagctgacaa tgtagcagcc tttgtcccac aatatttgaa gcgggtcgag
    39481 gcagaggaaa actggctcaa aactcatgct gccggtgatg acagccagta tgtcaagcga
    39541 gtttagcgat gatgtctatc caagaaaaag cagcagctgt ctatcaggtg ctaaaagagg
    39601 tctatggtca atccccttgg accttaaagc agatagtgtc tgatatgcag caggagcatg
    39661 ttgattattt taccttttat catcaggaga ccctgctagg ttttttagcg attcaacagc
    39721 tgccaggaga aatggaaatc actaatctag ctgttttgcc aagctatcag gggcaaggga
    39781 ttgcctcttg gctcatggga cagctagatg gctttgaggg agtgatattt cttgaggtta
    39841 gagcgtcaaa ccatagggcg cagcagcttt accttaagca tggctttgag gtggtaggcc
    39901 agcgtagcaa ttattatcat gatccaatag aagcagcctt gatcatgagg cgggaaggaa
    39961 agaatgacag atagatatat tttagcagtg gagagctctt gtgatgagac aagtgttgct
    40021 atcttaaaaa acgacaacgt cttattgacc aatattattg ctagtcaggt tgaaagtcac
    40081 aagcgttttg gtggagtggt tcctgaagtg gctagtcgtc atcatgtgga ggtgattacg
    40141 acttgctttg atgacgcact caaggaggcc cagcttgagg cttctgactt gactgcggtt
    40201 gcggttacct atggaccagg tctggtgggg gccttgctag ttggcctagc agcagccaag
    40261 gcctttgctt gggctaatga tttgcccttg attccagtca atcatatggc agggcacctg
    40321 atggcggcac gcgagcaagg agagctggaa taccctctta tggctctctt ggtttctggt
    40381 gggcatacag agcttgtcta tgtgaccgag ccaggagaat atcatattgt tggagaaaca
    40441 cgtgatgacg cagttggtga ggcctatgat aaggtaggac gtgtgatggg cttgccctat
    40501 cctgctggtc gtgagattga tcagctagct caccaaggga cagataccta tcattttcct
    40561 cgtgccatga tgaaagagga tcatttagaa ttttcttttt caggcctaaa atcagccttt
    40621 atcaacctgc accataatgc gcagcaaaag ggtgaggagc ttgtgcttga ggatctctgt
    40681 gcttcctttc aggctgcggt gttagatata ttgttagcaa aaacgaagaa ggcactcaag
    40741 cagtatccat caaaaatgct agtcgttgca ggtggagtgg cagctaatca gggacttcgt
    40801 gagcgtttag ctgaggaaat aactgatata gctgttgtga taccacctct aagattgtgt
    40861 ggagataatg ctggtatgat tgcgttggcg gcggtggttg agtacgagaa agggcatgtg
    40921 gcaggcttgg atctaaatgc taagccgagt ctagcctttg atagctttca tcagcagtag
    40981 tattagtatg aggagattgt catgttttat ttattgcttc ccccattgat ttgcagtgtg
    41041 gtatttttgg ctgtctatat taaggagcca agaacgctgt ggctaggagc tagctttgtg
    41101 acgaccctag gtgttagtct cttgtgtgct atgatttaca ttttttcaat cgaagaaaag
    41161 cttcagggag ttggtatcct agtgctaggt gttattgggt ttcttgcgat tgtatggttg
    41221 atgtctagtc cctttatcct cttgctcttt ctaagcttta atggcattag gctcatcaaa
    41281 agagaggggc tttcctttcg gaatttattg ctgattggct cagcggtgct attgtttgta
    41341 catcctttta tcagcagact attgttagag agtatcggtg attcaaagct tttaaggatc
    41401 atgtatgaaa cgagtgacct cttaatcctt tacctcttgt taatcgtatc agtctacacc
    41461 atctcaagca tgctgaatac cttttacttc agaaaaacca aggaggatta tattattgtg
    41521 ctgggcagcg gcttaaatgg agaccaggtc acccccttgc tagctagccg cattaataag
    41581 ggcattcaga tttaccagaa aaatcctggc agcaagctga tcatgtctgg tggcaaaggg
    41641 gctgatgagc taatagctga gggtgaggcg atgtgtcgct atgcaatcca gcaaggaatc
    41701 aaaagtgaag atatattagt tgaaaaccaa tccagaaaca ccagagaaaa tattctgttg
    41761 tctaagcaat taataccatc tggagcttcc ttttgcttgg tgaccaatcg ttaccacctg
    41821 tttagagcct tattactggc taaggagcta gccttgcctt gcaggtgcta tggggcaaaa
    41881 acaaagctct actttagtat gaatgccttt atcagagaga ttgttggcta tctccaatta
    41941 aagaaaaagc agcacctgct ggcaatgctc atcttaacag taggctatat agccataaga
    42001 gtggtgatga tctatatgct gcacatttga tgtcattggc aaaaaagcta aggctagtca
    42061 cctcgtcttg ggctgaaaaa gtctctctta ggtccttttc tcagatgata tgagcaagca
    42121 gcctttttaa aaaggctaca tctaggattt tatggagcct tagagcttgt tgtgtggtga
    42181 tgttcaatgg aaccaatcac aattgttaca gcaaaaagca ggcctttagg aacgtttgct
    42241 ttgctggtaa gtccttttac ttgcagaggc tggctacacc agccaaaggc taaggcaagt
    42301 gatttagctt gtgatgatca aggagtttta agacgtaaaa aaatagctcg gtatcttggc
    42361 ataccgagct atcatgataa attggcttct atgattacta aatcttaaac aaggtgagtc
    42421 aagcttacca gctagcctta gtgattcctg gtagttggcc tttgtgagct agctcacgaa
    42481 aattgatacg gctgacacca aacttacgca tgtaagcatg gggacggcca tcaattctat
    42541 cacgattttt caagcgattt ggatttgaat cacgtggcaa tttgcgcagt gcttcataat
    42601 caccctttgc tttaagctcg cgacgaaggt cagcatactg ttcaatcagt tggagctgct
    42661 tatggtattt agcaattttt gacttctttg ccattgcttt ctccttctta atatttaata
    42721 atctcagagc gttatcagca ccctgaattt cctcaaccag tcattaatca gttaagaaaa
    42781 catagctcta ttatacacta atttcaatca aatgcaagaa aaatagataa ctgattaacc
    42841 agttgaggca aaaacagcct gccagtgagt ctactgacaa gcctagctta gctttgcgag
    42901 cttcctgcca cccagccaga gcagagggca gctgtaatgt taaagccacc tgtatgagca
    42961 ttaacatcta agacctcacc agcaaagtaa agtcccgcga cctttttgct ttctagggtc
    43021 ttagggttga tttcttttaa gtcaatgcca cccttggtta caaaggattt ggccagagat
    43081 atttttcctg tgattggaat cggtaattgc ttaatcctgt tgacgagctc ctgagtctgt
    43141 gtgggagtta actgctttcc tttttctgga tagccctttg ctaaaaaatc agcgactcgc
    43201 tcaggcatca aagtcttgag cgcattttta agggcctttt cccggtgctg cgctagatag
    43261 ctgagcagct cagctgcgga ggtttgtggc agcaggtcaa gctctgcgat gtcacctccc
    43321 ttaacaaagg aggaaagcct gagagcagcg gggcctgaca acccaaaatg ggtaaaaagc
    43381 aaatcgtgag tgatctgatg tttcccacag ctaagggtca catcagcaag tgaaatcccc
    43441 tgcagagcct tatgtggaaa gtctgttaat aaggggcttt ccgcagcctc tagctcggtg
    43501 acagctatgt taaagtggcg agcaatatca tagccaaagc ctgtcgatcc agtagatggg
    43561 taggacttgc ctcctgttgc cacgataagc ctctcgcagc tgaaggtttg atcaactgat
    43621 ttgaggtaaa aaaggttatt ccgctttttg accgagacaa tctcggtact gatcagcacc
    43681 tgagctccta gtgacttgat tttttgctcc agcgcattga taatcgtctt tgattgatcg
    43741 gtcgtaggaa acatgcgtcc atgatcctct tccttgaggg tcaccccatt ttccttgaaa
    43801 aaggcaatga tgtcatgatt atcaaattgg gaaaagacgc tatagagaaa gcgcccgtta
    43861 ccgggaatgc ccgcgattag ctcatcatgg cttccgctat tggtgacatt gcagcgtcct
    43921 cctccagtcc ctgctagctt tttgcctagg cgcttgtttt tgtcaagtag gagtgtcttg
    43981 tagccatagt agctactaga gatggctgcc atcataccag caggaccacc tccaataata
    44041 atcgtgtcgt atagtatcat gtgcttattt tagcataaca tcaagcgatt taacagtaat
    44101 gtaaactagg ctaaattgac agaattctgg tattgtgtta ctatttttaa taagaatatt
    44161 cagttacagt aataaagagg aaattatggc aatagaaaag acagttagtg aactagctga
    44221 cattttggga gtgagccgcc aggctgtcaa taatcgtgtc aagtccttac cagaggagga
    44281 ccttgataaa aatgataaag gggtcactgt cgttaagcgt agtggcttgg ttaagctgga
    44341 ggaaatctac aagaaaacca tttttgatga tgagccaatt agtgaagaga ccaagcagcg
    44401 tgagctctta gagattctgg ttgacgaaaa aaacactgaa atcactcgct tatatgagca
    44461 gctaaaggca aaggatagcc agctggctgc taaggacgag cagatgcgta ttaaggacgt
    44521 tcagattgcc gagaaggaca agcagctgga tcagcagcag cagctgacag ctaaggctat
    44581 ggcagacaaa gagaccttga agctggagct tgaggaagca aaggctgagg ctgatcaggt
    44641 acgactgcaa gcagaggaga tacagtctga aatgggacct aaaaaaggtt ttttaaatcg
    44701 tttatttggt aaataacagt ataccaagac cctctaaggg tcttttttga ggagagaaga
    44761 atgaaacaat tagaagcata tattgccttt gatatggaat ttaatactgt caatgaggtt
    44821 agtcatatca ttcagctttc agcggtcaaa tggcacaagc atcaggaggt tgacagcttt
    44881 gacagctatg tttacactgc tgttcccctg caaagcttta tcaatggcct gacaggcatt
    44941 acctcagata agatcgtatc agcacccaag gttgatgagg tgcttgatgc ctttaagcaa
    45001 tttgtcggtg acacgccttt gataggctat aatgcacaaa agtctgattt gcctatttta
    45061 gcagcaaatg gcttggatct gtcagcgcaa tatgcagtcg atgtctttga tgaagcctat
    45121 gagagacgaa gcagcgacct aaacgggatt gctaatcttc gcctgcaaac agttgctgat
    45181 tttttaggga taaaaggaag aggacataat agcttagagg acgctcgtat gacagcgcgt
    45241 gtctatgaag cgtttgtgga atttgacgac aataagtctt acctaaacaa acaaaaagaa
    45301 gcgattgcag ataacccctt tgcagctctg ggagggcttt ttgactagca gcgctagtca
    45361 tttctctgaa aaagaaaaat gacctaaggt cagggcttgc ttgtgacctt gggtcatatt
    45421 ctataatgag gacagaaagg aggtgaagga catgtctgat atttactcaa ctggtgagct
    45481 agcaaaagca gcaggtgtca ctgtcaggac agtgcaatat tacgataagc gtgggatttt
    45541 gttgccttcc cagcttactg aaggtggacg gcggatttac accgagtcag atttggagcg
    45601 attgaaaatc atttgcttct tacgggacct agatttttcc attgagcaga ttaagcgcgt
    45661 gctagcagaa gacaatgtta tggcggtgct tgacctcttg ctggtggatc atatccaaca
    45721 gctggaacaa gacttaagga cgaaaaagca tcagcttgac acagctgtca agcttttgtc
    45781 aggtattcgc tgctcatcta gtcactctat caaaaaccta tcagacatgt cacttaccat
    45841 gaacaatcaa aaagcttggc gtcgtttgca gttgaaaatg tttagtaata ttgccctagc
    45901 aatattggtt catgtgatgt tagtgttact aactagctat tttcatctat cttggttggt
    45961 atggatagag gctccactat ggataatctt ttttacttta ttgatcgttt attttcgtaa
    46021 acaatttgag tacctatgtc caaattgtca tactattttt gaaccagact ttaaagagtt
    46081 tgccttggca ggtcacacac caaggacccg caggctgacc tgtcctcatt gccatcaaaa
    46141 atcttactgc cttgaattgg ccaaggaaaa ataatggaaa atctccgctg gatacccagt
    46201 ggagatttct tgctattaga atggtagctt gccagcaaag gctcctagag ttttcttagt
    46261 cgcctcatca atttgagcga gggctgcatt gatggcctga gcagtcatat cctgaagtgt
    46321 ctctatatcc tctgggtcaa cgactgcttc cttgaaatca atgctaacca attgcttatc
    46381 acctgtaaag gttgcagtga ccagctcctg agctgacttt cctgtaaatt gcatagctgc
    46441 taggtcagcc tgcttttgtt ccatttgctt ttgaagcttt tgcgcttgct tcatcatgtt
    46501 ttgcatgttc atcataagtt ccaattctcc taagttttga tacttaacta ttataacata
    46561 tcagacaaga cttcaaacat gtgatctttt aaagttaatg aaaaggccct gctagcctgc
    46621 aatgctttga tgtgctagcg actaacgaac aggtcgtttc ctttaaatag agttttcttg
    46681 ttgagcttta tagctggtgc ttgtttttgt gatgagcttg tgtgaggctg tcgttagtgt
    46741 tgttttaggt ggtttgacat caggagcgat taaaaaagtt atcagtttac atttttataa
    46801 taataactta agaattaatt taactttaga ttaatcttac tttatatttg attgctatac
    46861 ttagtccata acataaataa ccaaaaagaa agaggtaatc gttatgacaa caatgactac
    46921 aacaaaacaa tcaaagacaa ctctagcagc tcgttatttg aagcttggtc ttacttcagc
    46981 aatgtttgct ggaggagcct ttctagctct aggctcagca ccggctgtct ctgcttctac
    47041 ccatgctggt aatgatcagc cagcgactca acgcttaact gatcaggaga tctacgaacg
    47101 tgctcaaaag ctagacttgc cagactatgt gagaggctca atctacggta ttctcaacca
    47161 aaactcaagt gttacttatc caaaggatat agcaggtcta gagcagtcag aagctccaca
    47221 accccctgca gctccacagc tcactgacca agatgctcaa aagctggact tgccagacta
    47281 tgtgagaggc tcaatctacg gtattctcaa ccaaaattca agtgttactt atccaaagga
    47341 tatagccggt ttagagcagt cagaggctcc acaaccccct gcagctccac agctcactga
    47401 ccaagatgct caacagctag acttgccaga ctatgtgaga ggctcaatct acggtattct
    47461 caatcaaaac tcaagcatta cttatccgcg cgattattaa gcatctaaga tgattaaggt
    47521 gcacaatcga cgattaaaat gattgatgag ttaatgagat tagaattatt tggctaagtt
    47581 aagaattagt gttatacttg agagagtgta gcactaattt tttaatcaag gaggaagcat
    47641 gacctacaag atattattgg tggatgatga attggaaatt attgatatta acgaacgtta
    47701 tttgcaacag gcagggtatc gtgttaccac tgcaagcgat ggtagtcaag ccttggagct
    47761 ttttcataag gatcagtacg atttgattat cagtgatgtt atgatgccca atatggatgg
    47821 ctatgatttt attggggagg ttttactgga aaagccagat cagccctttc tctttatcac
    47881 tgcaaaaaca tctgagcctg acaagattta ttccttgagc ttgggagcag atgattttat
    47941 ttccaagccc tttagtccac gtgaattagt cttacgggtc aaaaatattt tgaatcggat
    48001 ttatggtaag gctaaccaag ctgactcctt agttattggg gatttggtca tggatcacag
    48061 cactcgaagg gttacagtgg caaatcaaga tctgaatctg accaacaagg cttttgattt
    48121 gttgtggatt ttggccaatc atttgaatca tgtcttttca aaaacagagc tttatgagcg
    48181 t
//
LOCUS       DARYLJ010000011        44059 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYLJ010000011 DARYLJ010000000
VERSION     DARYLJ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44059
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(22..1293)
                     /locus_tag="TU746_000566"
     CDS             complement(22..1293)
                     /locus_tag="TU746_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL0890939.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
     gene            complement(1286..1894)
                     /locus_tag="TU746_000567"
     CDS             complement(1286..1894)
                     /locus_tag="TU746_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL0890940.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(1935..3671)
                     /gene="pabB"
                     /locus_tag="TU746_000568"
     CDS             complement(1935..3671)
                     /gene="pabB"
                     /locus_tag="TU746_000568"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL0890941.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            3820..4290
                     /locus_tag="TU746_000569"
     CDS             3820..4290
                     /locus_tag="TU746_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL0890942.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4292..4636
                     /locus_tag="TU746_000570"
     CDS             4292..4636
                     /locus_tag="TU746_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL0890943.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            4653..5081
                     /locus_tag="TU746_000571"
     CDS             4653..5081
                     /locus_tag="TU746_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0890944.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(5279..7816)
                     /locus_tag="TU746_000572"
     CDS             complement(5279..7816)
                     /locus_tag="TU746_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0890945.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            8379..9332
                     /locus_tag="TU746_000573"
     CDS             8379..9332
                     /locus_tag="TU746_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL0890946.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            9332..10078
                     /locus_tag="TU746_000574"
     CDS             9332..10078
                     /locus_tag="TU746_000574"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL0890947.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            10327..11331
                     /locus_tag="TU746_000575"
     CDS             10327..11331
                     /locus_tag="TU746_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0890948.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            11628..13814
                     /locus_tag="TU746_000576"
     CDS             11628..13814
                     /locus_tag="TU746_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL0890949.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            13892..14713
                     /locus_tag="TU746_000577"
     CDS             13892..14713
                     /locus_tag="TU746_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL0890950.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVSLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(15009..15467)
                     /gene="nrdI"
                     /locus_tag="TU746_000578"
     CDS             complement(15009..15467)
                     /gene="nrdI"
                     /locus_tag="TU746_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL0890951.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFSVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(15863..17047)
                     /gene="sezV"
                     /locus_tag="TU746_000579"
     CDS             complement(15863..17047)
                     /gene="sezV"
                     /locus_tag="TU746_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL0890952.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            17297..18901
                     /locus_tag="TU746_000580"
     CDS             17297..18901
                     /locus_tag="TU746_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL0890953.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLSDIAISGDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGRDDY
                     YNLLMHLSSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDRYAKLLEAKLAAIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            19124..21343
                     /locus_tag="TU746_000581"
     CDS             19124..21343
                     /locus_tag="TU746_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL0890954.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            21358..21801
                     /locus_tag="TU746_000582"
     CDS             21358..21801
                     /locus_tag="TU746_000582"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL0890955.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(21928..23220)
                     /locus_tag="TU746_000583"
     CDS             complement(21928..23220)
                     /locus_tag="TU746_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL0890956.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            23975..24823
                     /locus_tag="TU746_000584"
     CDS             23975..24823
                     /locus_tag="TU746_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL0890957.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            24973..26106
                     /gene="ugpC"
                     /locus_tag="TU746_000585"
     CDS             24973..26106
                     /gene="ugpC"
                     /locus_tag="TU746_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL0890958.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            26290..27909
                     /locus_tag="TU746_000586"
     CDS             26290..27909
                     /locus_tag="TU746_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL0890959.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            28018..28380
                     /gene="traF"
                     /locus_tag="TU746_000587"
                     /pseudo
     CDS             28018..28380
                     /gene="traF"
                     /locus_tag="TU746_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            28494..28853
                     /gene="yajC"
                     /locus_tag="TU746_000588"
     CDS             28494..28853
                     /gene="yajC"
                     /locus_tag="TU746_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL0890960.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            29027..29776
                     /locus_tag="TU746_000589"
     CDS             29027..29776
                     /locus_tag="TU746_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL0890961.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            29786..30580
                     /locus_tag="TU746_000590"
     CDS             29786..30580
                     /locus_tag="TU746_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL0890962.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            30612..31877
                     /gene="rseP"
                     /locus_tag="TU746_000591"
     CDS             30612..31877
                     /gene="rseP"
                     /locus_tag="TU746_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL0890963.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            32147..34003
                     /locus_tag="TU746_000592"
     CDS             32147..34003
                     /locus_tag="TU746_000592"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL0890964.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            34055..34612
                     /locus_tag="TU746_000593"
     CDS             34055..34612
                     /locus_tag="TU746_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL0890965.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            34947..39344
                     /locus_tag="TU746_000594"
     CDS             34947..39344
                     /locus_tag="TU746_000594"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL0890966.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            39466..39894
                     /locus_tag="TU746_000595"
     CDS             39466..39894
                     /locus_tag="TU746_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0890967.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            40024..40569
                     /locus_tag="TU746_000596"
     CDS             40024..40569
                     /locus_tag="TU746_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL0890968.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(40748..41362)
                     /locus_tag="TU746_000597"
     CDS             complement(40748..41362)
                     /locus_tag="TU746_000597"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0890969.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
     gene            41727..43154
                     /locus_tag="TU746_000598"
     CDS             41727..43154
                     /locus_tag="TU746_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL0890970.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            43420..43689
                     /gene="rpsO"
                     /locus_tag="TU746_000599"
     CDS             43420..43689
                     /gene="rpsO"
                     /locus_tag="TU746_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL0890971.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            complement(43781..>44059)
                     /locus_tag="TU746_000600"
     CDS             complement(43781..>44059)
                     /locus_tag="TU746_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL0890972.1"
                     /translation="WQYQHQSYHHFLETKGIRPSMSRKGNSPDNGMMESFFGIFKSEM
                     FYGLETTYQSLNELEQAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
BASE COUNT        12421 a         8752 c        10482 g        12404 t
ORIGIN      
        1 tttcttgttt ttttctttag gctagctgct agaaagctta tcaattcgcg ctttattggc
       61 ggctaaggct ctttcatatt ttcctgtttc atttgggttg aagtaatttt tcttaaccaa
      121 gtgatcaggg agatattgct gcttgaccca tttttctgga tatgcatgag ggtaaaggta
      181 gtgctgagca ttgcctagct ccttgctgcc ggcataatgc ccatcacgca ggtgtctagg
      241 aatgggaaga tggccatgtt gacgtaaatc agcgagagca gcgtccatag ccatataggc
      301 ggaattggac tttggtgaca gtgctagatc aatcacaaca ttggcaatga ggatacgcgc
      361 ctctgggaag ccaattttct gggcggcctc aagtgcagtg acggtatgga tttgagcttc
      421 tggattggca agacctatgt cctcataggc gataatggtc aagcgtctag caagactcgg
      481 aagatcgcct gcctcaataa gccttgcagc atagtgcaag ctagcattaa catcagatcc
      541 tcggattgat ttttgcaagg cagatagtat gtcataatgt ccgtcgccat ctttgtccat
      601 tgtgatgtag ctgcgctgca aagaattttc aacagtattc aagctgatat gacggatacc
      661 ctcggtatct ggctgggttg acatgacagc tagatcaagg gattggtagg cggctcggag
      721 atctccattt gtcgctgtcg caataaagtc aaaagcagcc tcatctaggg tcacatcaaa
      781 ggcaaagcct ctctccttat cagtgatggc aagcttaagc gcctgcttga tctcctcagg
      841 tgataggggc tccagctcaa aaatctggac tcgacttctg atggctggag taaccgagaa
      901 aaaaggattc cctgtggtag caccaatcat aataatgtgc ccatgctcta aaagtggtag
      961 taaaaagtcc tgcttactct tatccaatcg gtgaatttca tcaagcaaaa gcacaagtcc
     1021 acctgaaaac ttagcttcct cagcgatttc ttggaggcgt tttttattgt ctatggtagc
     1081 attgaaggtt ctaaaggcgt acttggttgt tccagcaata gcactagcaa ttgatgtctt
     1141 tccaataccg ggaggtccgt aaagaatcat tgaggctaat ctattggcct tgaccatgcg
     1201 gtcaatgatt tttccctccc cgaccagatg ctgctggccg atgacctctg taatggttct
     1261 agggcgcatt ctgatggcta gattatcagg cattgtattc ctcccttcct tgcttttgtt
     1321 ggctgtggtg ctttttaaca acagccataa agtttgcgat cattgtccta ccgtcagctg
     1381 ttccgatgct ttctgggtga aattgaaggc caaacagtgg cagctgtctg tgttcaaagg
     1441 ccataatctc attgtcctca aagtctcttg cggtaattac aaagtcagct ggcaggtcat
     1501 caacaacaat agaatggtaa cgcatgacgg ttaattgctt tggcagctgt tgaaagagct
     1561 tagctggtgc ttgtctttca agtatacttt gcttgccatg catgacgcgc ttagcaaggc
     1621 gtagcctgcc acctagagcc tcagcgatag cttggtggcc aaggcaaacg ccaagcatag
     1681 gcttttggtc ataaaaggcc ctaatcaagc taggcatctg attggcggct ttgggccagc
     1741 cgggtccagg tgagaggact atggcgtcag cctgcttcgc aaggtcaaat agttttggat
     1801 cctgattggt caatacaatc gtttgatcaa aggcactgag gtattgggcc agattatagg
     1861 taaatgaatc gtagttatca attaaaagta tcataaggtc cttcatctag tagtgctgag
     1921 ggatcagcct ggtactattg aggcagagtg gtgtcctcaa ttgttagtga gtagagtcct
     1981 cggacagcat tgccaccaaa aatggcttcg gccttgtcta aatctgaaag ctttagctct
     2041 ttttcctgag ccagtccctg ccttagtaat tcttgacgga aaatgcctgg tagaataccg
     2101 gctgatacag gcggtgtata aagggtctgc tcgatttgca caaaaagatt accaatagag
     2161 gtttcaagca aggtcccatc agcagcaaca aagacttgct cataaggctt gacgctcaga
     2221 tgtggtcgat gactggtttt aaaataagta aagggaagct ttttgacatc gcttgattgg
     2281 cgaactaatc gtgcctttaa aaagtctttt tgaagcggct ctaagctttg gtctgtaagg
     2341 ctaatctgcc cgtccttagc aatagcaata gtgagacgat aggggctgct gtcctttccc
     2401 ttgagatagg cttgcaaacg atctgtcaga agctcttcgt cataggggta ggcaaaataa
     2461 cgcgccgcct cccttagtct gttgaggtgc tggtctagat atattaggct ttgttgttcg
     2521 accttggcag tggttttgat ggtgaaatca atgctttgac ggttcagaaa ggaagatttt
     2581 tgcttgattt cttcaaattc gtcctgccag cagctttccc aggtaatccc accgcctacc
     2641 ccgtagatgg cctgatcgta gctgagctga atcgttcgaa tagcgacatt gaagacacgt
     2701 ctgccatcag gcaggcaaat accaatgctg ccacagtaaa cgccccttgg cttaggctct
     2761 aatcggttaa taatagccat tgtagacacc ttaggagctc ctgtgatgga gccacaggga
     2821 aagagtgcct gtaaaatatc ataaagacga cactgatcct gcagcatgcc gacaatggta
     2881 gaggtcatct gccaaacggt ggaatattgc tccaattggc agagctgtgt gactgtgaca
     2941 ctcccagttt gacagatctt attcatatca ttgcgtaata aatcaacgat catcatgttt
     3001 tctgaacggt tcttaggatc ggcctgtagc cagtcatgct cttgttgatc tagttctaaa
     3061 ttgtaaccac gcttggttgt gcctttcatg gggcgtgtgg tgatctggtt tttctcttgc
     3121 ttgaaaaata actcaggact ggctgaaatg acagcaaagt catcgtgagc aatgtaggca
     3181 ttgtatccag ctgcctgttc aatgaccaat tgatgataaa tggccaagct gtccttagcg
     3241 tttagccttt ggctgagctg aatggtatag ttgacctgat aggtattgcc ctgcctcatc
     3301 tcctgatgaa tctgtgcaat agcctcttga taggcttcct cttgtgtagc acttgtccag
     3361 ctgtttggaa tcgtcatgct gtcgtggtag agcggaaagt cctcgagctg acagctgtca
     3421 tgcactgtaa aataagcaaa atattcctga ccaagtcttt tattgtgtgt tgttagcttt
     3481 ttgtcaaaac aggctgctgc ttcatagctg aggtagccca caacatagta gcccagatct
     3541 tgaaattggt tgacctgctc aaggacctgt cccacctgat caatctgctt agctactaat
     3601 tccacgatag gagcttgaaa tatatagcgt tgtcccagct ccttaaaatc aataatcgtc
     3661 tttatatgca tagcttgatt atatcataaa tgcgcttttc agactgatta ggagggttga
     3721 aaagaagcct gttagcaacc atcaacaata caagagagca gggcttcttg atttatgcta
     3781 caatagtagc ggatattatt tagaaaaagg aacaagagca tggctaaata tggcttttta
     3841 tcagtattag aagaagagat ggacaagcat tttcattatg actatgctat ggattgggac
     3901 aagaaaaatc atgcggttga aatcaccctt gttttagagg ctcaaaatca gtcagcagtt
     3961 gaaaccattg atgaccaagg acagctcagc aaggaagaca ttgtctttga ggattatgtc
     4021 ttattttaca atccggagaa atcacagttt caagcagcag actatctggt ggctattcca
     4081 tttgagccaa aaaagggctt ttctcgtgaa tttttagcct attttgccca gtttctcaat
     4141 gatgttgcca ttgaagggca tagcgatttg atggatttct tagcagatga tagcaagctt
     4201 gattttagtc tagagtggaa cgaggaggcc tttgaggaag ggcaggtagg actagaggaa
     4261 acagagcttt atagctatcc gaggtattaa gatgctacat gagatgatgc tgacaccaag
     4321 accatttgct atgattgagg cgggtgtgaa gactattgaa ctacggttaa atgatgagaa
     4381 aaggcaggct attaaggtag gggattggat ttgcttttat tgtacagagg atcatagcca
     4441 tattctgcaa gcagaggtcg tagggttgca ttattttgat gactttgcta agctttacca
     4501 agcattgcct ttagaaaaat gtggttatcg taatgaagaa ttggcactgg ctcggccgga
     4561 ggatatggaa cagtactaca gcaaagagca gcaagcccaa tatggcgttg ttggtattga
     4621 gctaaggcta tgttgattgg tgagatctag tcatgaagct tttagataaa acagtccatt
     4681 tttctggtgc aaagttagcc ttgatcagta acggtaagat tttgaccatc ttgcgtgacg
     4741 cgataccaac gattccttac cctaatatgt gggatttacc aggaggtggt cgtgaaaatg
     4801 ctgaagctcc ctttgattgt gcgtcacgtg agtgctatga ggagttaggt ctggcactga
     4861 ctaaggacgc tgtcgtttgg gaaagggttt atccagggct tgttaatcct gacagccaat
     4921 ctgtctttct ggtggctctt atgaatcagg acatgataga tcatattgct tttggtgatg
     4981 aggggcaggg ttatcagctg atggctattg atgacttttt agcagacgat cgggtcattc
     5041 ctcagctaaa ggctcgctta gctgattatt taaggaaata ggcagactta gctggtacac
     5101 taaacagatc agcaaacacc actactatgt gatagctacg accagaatca aaaagacgat
     5161 tgacctctgc ccacatgtgg ctaggatcaa tcgtctttgt ttttggggtg gctaagtctt
     5221 taatctggta ggccagatca gctgagtagt tgatattatc aatcagtcct gctatggctt
     5281 agctgttgct agctactgat gtgctgctag ctgtctctga ctcacctaaa aaatagctgg
     5341 ctggcttatc acttactggc gtcttaccaa caagctcagg gtcaggtgct aataggtcgt
     5401 cctcgtcgga gtcagaaacg ggcgctacaa attcttctag ccagcttcca gtgctgccag
     5461 tgtgattagg agtttgaggc tccttaggta gtggatcacc tggtagccag gtattccctg
     5521 agtgattact attacctgta acatcgttgt tggttatttt atcaaagttg acgttataaa
     5581 caatatcctc agtgacttcc ttatcatatt cctcagttga aataataggc ttattgtaat
     5641 cacgcttgta gccggcatct ggctgtactg atggtggtag gataccagct gtatgtaatg
     5701 agtgtccctt acgaacaagg taaacggcag tcttaccctt accagctcgg ctaatcagct
     5761 gtccgccctc tcctgcctta aaggcaacgg ctacatagtg tctcggatcg tggaagtaat
     5821 aattagggtg tctgctagga tcctctagat cagttggctt gtcaggatta acagcgatgt
     5881 aaggtccaat ataaggagca gtagttccaa aggctgctga gaataggcca gtaaaggcta
     5941 ccttatcgtt ttcattttgt gtgatagaaa atctcttagc aaaatcagtt agattaaagt
     6001 tattggcaag gttcactcca ctgcggtatt caataaattc atagcctgga tctgggacgg
     6061 gctcagggat aacaagtcct tgctccttag cttccttcca ggtaagacca ctacgaacat
     6121 tgtagaagaa gcctccttga gtcacgccgt taagcttcaa tcgcccatta aagattgtgg
     6181 tgaaccagac aggaacataa ttttctaagt caaggtctga aacatcatca cctggcccgt
     6241 agacagcctt ggtaggctgc tttctaacct tatcaaaatc tacatagaag cgttgatgtt
     6301 ctctgtccat cttgccagct gttggcaact cagcactcca gcccttaaag atacgcccct
     6361 catgcttgat tgcctctgga cgctgaatgt tcaaatcctt ccagtccaaa tccttacgaa
     6421 ccaaatagtg cacacgttta gttttaatgc cattaacctc aatgtcgccg tattcactat
     6481 ttgtactaaa caacacatgg ataaagtttt tgatgttttt gatgccctct gggtgatatt
     6541 ttttatagac cccatcacgt gttagatttt cagatgaatt ttccgtatag aaaggaccat
     6601 aaacgagctg agtttcgacc tctagattgg ttgattctgt cttgacattg cgctcaggat
     6661 catctggcaa ttctgggtca atcttataga tgtgagcatg gtccccatga ctaatggtca
     6721 tgtagttgcc ctcaattgag atgtcctcac gacgaacctt gaagcgatcc ataaattctt
     6781 tgatgagtct ttctttgcgc tgttcaaagg tttctccgtc tatctttttg aggatctgtt
     6841 cttctggagt tttaaatggc ttagaaagat caatatcctt tagccagatg acgtgcgtgt
     6901 ggtcctcatg agggtattca aagccgacct gaccgtctac attcacctgc ttaatgcgtg
     6961 cttgatctac ctttagctcc ttggcgagat aagctatata ggcgcgatag tctccttcct
     7021 gaggcttggt gtggtccttt ttcttatatt gctccactaa ataagcccat ttgctacgct
     7081 ttaagtcctc aaagctaata gggtgcaaat ggttcccatg cttcaccagg attccagtgt
     7141 cagtgacacc gctaatgttg gtgccatcaa ataagaagcc atcactagtt ttgaagtcaa
     7201 ttcctgggat acccccctgc tgatgaatgc taggtggtgt tgatgggaag tgaggtgtgg
     7261 ttgatgcgat gtggttgatg gttgctgatg gcaggcttga tttgaggata tagtggtaat
     7321 gatctccatg acgaacagtg tagccatagg cgtcctcagc aacaatgtca gctggattaa
     7381 agacatagcc gtctccagca tgaccagttg agactactga tccagacctt gccgcttggt
     7441 tagaagcagg ctgtgcttcc ttgtaatcct taggaatcag gtaagcccat tttgtcccct
     7501 tcaaatctga gtaaaagaag aaatgcttgt gatcgccatg cttcacaatg atacctgtat
     7561 ctgttttgcg ttcaatttgc gattcgctgg tcaataaaaa gccatcatca gttgggacat
     7621 caatcccagg gacttggtga cgttctcttt ttttcgcagt cttactgctt ttttgttttt
     7681 tctttttcgt agccttttgg tgctttttag gctcctgaga atgtcccttt tgcgaatgcg
     7741 tttggcaggc tgttaaggca aggttgcagg ctaacagcag tccaacgagg gataaaaatc
     7801 gttgatgttg tttcatggtt agttatcaac tccttccaac aattaactta accagttaat
     7861 attattactg gttaagtata tcatttgaca tctaagaata caatagattt tataaatttt
     7921 ttaatgaaat taatctaatg acctaagagc tgtctggaag atgaaaggct ttttagctat
     7981 ttcaaaggct tggagcttca acaggcgaat cagctattgg tttttctgga tttacgagaa
     8041 agagctgctc ttttttgatg tagctggtat aaaatatggt aaaatagggt ctatcaagag
     8101 cctatctacc tttagattgg ctgagatttg ttaggcaatg cgtccctgat aaaggttggg
     8161 cttatgggac aataggcctt ggtgctgtgt ttgtccttag tatgaaacct ctgagacggc
     8221 agagcaggat ccggttggtt taggaccgca ttagcttatc ttacgataaa aaagaagctt
     8281 gaaaggaaag gctgctttga tctgatagag ggtcactggt tttagggttt aggctagggg
     8341 caagtgacca ctgatgatat ggcagcaagg gtatcgttat gaaggcatgg caagagctga
     8401 caattacagt ccatcgtgag gcagaagaag ctgtttccaa tctgctgatt gaggctggca
     8461 gccaaggagt cgctatcaat gacactgcag actatatcgg tcaagaggac cgttttgggg
     8521 agctttatcc agctgttgag cagtcagaaa tggttactat tacagcctat tatccaagct
     8581 cagctgatat tgatgacatc agacagacca ttaatcaggg cttgaacagg ctaaagcagt
     8641 gtgatgtgga gcttggtgag ttaaccctga ccaatcaaga attggctgaa gaggattggg
     8701 cggacaactg gaaagcctat tatgagcctg ctcgtatcac gcatgatttg acgatagtcc
     8761 ccagttggac agattatgaa gccacagcag gtgagaagat cattaggctt gatccgggta
     8821 tggcatttgg aacaggcaca cacccaacaa ctaagctaag cctgtttgcc ttggagcagg
     8881 tgcttcgtgg tggtgagaca gttattgatg tggggacagg ctcaggtgtg ctatcgattg
     8941 ctagctctct gcttggcgcc aaagaggtct ttgcttatga tttagatgat gtggcggtgc
     9001 gtgttgccaa agacaacatt gccctcaatc aagccactga caatatccat gtagcagctg
     9061 gagacctgct aaaaggcctt actcaagagg cagacgttat tgtcgccaat atcttggcgg
     9121 atattttggt gcatgtgaca gcagatgctt accgtcttat caagtctgag gggtatctga
     9181 tcatgtcagg gattatttca gaaaagctgg atatggtgaa gcaggctgct cttaatgcag
     9241 gcttcttgct agagactcac atgcttcagg gcgagtggaa tgctcttatt ttcaaaaaaa
     9301 cagatgattt atcaggagtg attggtggct gatgcagcag tattttatta aaggcagggc
     9361 agaaaaaatc gttcagctga ccgataagga taccattaag catatgtttc aagtgatgcg
     9421 cttgacggat aaggaagagc tggtgctagt ctttgatgac ggcattaaac gcttggcaag
     9481 ggtgtcagac agctcagcct atgaggtgga gcttatcaaa gagctggaag aaaaccttga
     9541 aatgcctgtt gaggtgacta ttgcctcagg ctttcccaag ggtgataagc tagatgttat
     9601 cactcaaaag gcgactgagt taggggcagc agctatttgg ggctttccag cagactggtc
     9661 ggtggtcaag tgggatagca agaagctagc taaaaagcaa gaaaaattag ctaaaattgc
     9721 tcttggagca gcagagcaat ccaagcgtaa tcgcgtaccg gagattcaac tatttgacca
     9781 aaagggtgag ctattaaagc agcttaagca gtttgataag tgctttatcg cttatgagga
     9841 agcagctaag gcaggtgaaa ggtcgacatt ggcgcgtgag ctagcaggtc ttagcccagg
     9901 tcaaaaagtc ctctttatct ttggaccaga gggtggtatt tcttcaaaag agctggctag
     9961 ctttaagcaa gcaggtgcta ttactgtggg actggggcct cgtatcatgc ggacagaaac
    10021 agcaccgctc tatgccttga gtgctgttag ctatgctctg gagctaatgt ctagctgata
    10081 gtgctaatag gagacagcac cttgtggctc agtgcttgac agaaaaaaga ggagcatctg
    10141 cgattatgct aataaagcac cgcttaacaa aaagatcgct aagaaggaga ctgccgcaaa
    10201 tcaaagggct agtctagccc gcgtaggtgc agagctgtcg ggcctttgca gcttcatttg
    10261 taaaaaatat aacaaatcat ctcaaaataa agatactcgt caaacggatt ggtagaggag
    10321 ggacatgtgg ttacgataaa agatgtggca aggctagcag gagtttcgcc ttcaacagct
    10381 tcgcgtgcca tcaatgacag tgacatgatt agtcaggcga caaaggagcg tgtcaaaaaa
    10441 gccatggagg ccttggatta ttcgcctaat tattcggcgc aaaaccttgt taagcgaaag
    10501 tccaatactg tcgggatcat tttgccggtg cgtgagggtc aggattcact gggaaataac
    10561 ccttttttca tgcagattat tcaaggaatt gctgctgttt gtaccgatca gggctacatg
    10621 gtagcccttg cgactggacg tagtgaggcc gaattgctaa aaaacgtgca aaacatgatc
    10681 cgtagtggca atattggcaa gctgattttt ctttattcca aaacagatga tcaggttttt
    10741 gactttgtca aaaggcaaag agtggattgt gttgtcgttg ggcaatcaac gacaaaggat
    10801 cctggcaatg ctaaatttgt caacaacaat aaccatcaag ccggctatga tgcagcagca
    10861 tttctccttc aaaaaggcta tgaggctatt gtctatgctt atactgacat ggccgaattg
    10921 gtgcaggcag agcgttataa gggctatgca gagctgatga cttcaaaggc tctggcagct
    10981 caagcccttt gtgtcacgct aaaggacgat aggaaaagtc aaaagcagct gttagaccaa
    11041 ttagccaagc gctctaaagt tgcctttgta gtctgtgatg atgtgctagc tattcatttg
    11101 cagcgtctca tcaagcaagt agcagctgac acccagctag caatcgttag cttcaataat
    11161 tctgtcctag cggagcttgc gagtcctgcc ttgacctcca ttgctatttt tccctatcag
    11221 ctgggagagc aagctgctga gctggtctta tcaagcgcag cgccatcacc acagccagtc
    11281 ttagttcctc atcagatcat tgaaagagag tctacgcctt ttattgtttg atttaccgtt
    11341 aagcctattc ctaagcaaag tactgatagc ttgcttagga ataaggcttt ttatttagga
    11401 atttattttg tttgctaata gtattaaaga gaagcaacgt ttactttagc attttcattg
    11461 aaatcttctt aagaaaacgc tttacaaaac aaaaaaaggt tggtaaaata agcttatcaa
    11521 aagcgcaaac gtttgcgttg aatgtgcttg tttttaaaaa ggaattgaga gttcatcagc
    11581 ttttagctgg ttattcttga ttcctagtcc aaaaaaggag aggtcgaatg aaaacatcat
    11641 tcaaacaatt ttttagcttc gagttttggc aaaaattcgg gaaatgcttg atggttgtca
    11701 ttgctgttat gcctgctgca ggtttaatgg tgagtattgg aaattctctg cccatgctta
    11761 atcaggagtc gcagctttta gcgacgcttg gtaatgtcat tgctcaggtt ggttgggcag
    11821 ttattggtaa ccttcatttg ctttttgccc ttgctattgg tggcagctgg gctaaggagc
    11881 gtgctggcgg tgcctttgct tcagggcttg cttttgtttt gattaaccgt attacagggg
    11941 ctatctatgg cgtttcttca gccatgctga ctgatccaga ggccaagatt aaaagtcttt
    12001 tgggcactga gatgattgtc aaggactact ttacaagcgt cttagagtca cctgctctaa
    12061 ataccggtgt ctttgttggg attatcgctg gctttgtggg tgcaacagcc tataacaaat
    12121 actacaatta ccgtaagctg cctgatgtgc tggctttctt taatgggaaa cgctttgttc
    12181 cttttgtagt tatccttcgt tcagctcttg tggccctagt attagccttg atttggccag
    12241 ttattcagtc tggtattaat ggctttggca tgtggattgc ctcatctcag gacacagctc
    12301 caatccttgc gccattctta tatggaacat tggagcgtct cttgctgcca tttggccttc
    12361 accacatgct aacgattccg atgaactata cagctcttgg gggcacctat gaggtcatga
    12421 caggagcagc tgctggaact aaggtatttg gtcaagaccc tctttggcta gcctgggtta
    12481 ctgaccttgt taatctcaag ggctctaatg cgtcaaccta tcagcatttg atggagactg
    12541 ttgttccggc tcgttttaag gttgggcaaa tgattggtgc aacaggaacg cttatggggg
    12601 ttgccctagc aatgtaccgt aatgttgatg cggacaaaaa gcataaatac aaaatgatgt
    12661 ttatctcagc agcggcagcg gtatttttga caggggtcac tgagccactg gaatacatgt
    12721 ttatgtttgc tgcgatgcca ttatatcttg tctatgccct tgttcaagga gcttcctttg
    12781 caatggctga tttggtcaac cttcgtgtgc attcctttgg taatatcgag ctattgaccc
    12841 gaacgcctat ggcgattaag gctgggcttg gtatggattt gattaatttt gtctgggtgt
    12901 ctattctgtt tgctgtgatc atgtatgtca ttgctgactt tatgattaaa aaaatgaagc
    12961 tagcaacagc aggtcgccta gggaattacg atgctgatat actagaaaac gatgatacaa
    13021 agcctttgtc acagcagtct attgatggtc agtcacaggt cgtccaaatc attaatctcc
    13081 tgggtggacg tgagaatatt gctgatgtag atgcttgtat gactcgcttg cgtgtaacag
    13141 tcaatgaccc aagcaaggtt ggcagtgagg agcattggaa gcaggcgggt gctatggggc
    13201 taatcatcaa gggcagtggt attcaggctg tctatgggcc aaaggctgat attttaaaat
    13261 cagatatcca agacctgcta gactctggtg cagtcattcc agagccgaag cctgctcagc
    13321 ctgctgcctc atcatcacag cagacggact ttaaaaacct aacagaggct gttttggcag
    13381 tagcagatgg agaagtcttg ccaatcacag cagtttctga tcaggtcttt gcagctaaaa
    13441 tgatgggaga tggctttgct gttgagccgg caaatggcgc tatctatgcg ccggtaacag
    13501 gtctggtaac ccatgtcttt ccaaccaaac atgcctttgg cttgctgaca gatagcggcc
    13561 tagaggtgct ggttcacgtt ggtcttgata ccgttgactt gaatggtgag cccttcactg
    13621 tcaaggttag tgagggtcag cgcgtatcgg caggagatct cttggctgag gctgacctaa
    13681 ctgcgattac agcagcagga cgcaagacaa cggttgttgt cgcctttacc aatactacaa
    13741 gcatcaaagc tgttaacctt gttgcgactg gtcaacaaaa agcgaagacc ctcgttgcac
    13801 aggtagagct ttaagaataa ccaaagagag tggtagatag cagtatgtca gacctgcagg
    13861 ctgccacttc tcttgtcgta taggagaaga tatgaccaag ctcttaaccc ttaacacaca
    13921 ttcttggatg gaagccaatg ccttaaaaaa gctgttcgac ttggcagagc atattttggc
    13981 tcagaactat gacgtgattt gcctacaaga aatcaatcag ctgattgaca gcgaagcagc
    14041 agtgtcatta tcaggctacc agccaattgc agggacacct gccattcatc aggataactt
    14101 tgccctcttg cttgtcaatt acttaaaaaa acgtggccaa agctactact ggtcgtgggc
    14161 ctacaatcat attggctatg atatttacca tgagggtgtt gcgatcttat ccaagcagcc
    14221 gatccaagcc tcagacattt tagtctcagc ggtggctgac gagtatgatt accacaccag
    14281 acgggcttta ctggccaaaa caaccattga tggcagggag gcagcagttg tgagcctgca
    14341 tttgtcttgg tttgatcagg gctttgtcgg agaatggcag cgattagagg cagccctgca
    14401 gcagctagcc tgtcctgtgc tattgctggg agattttaac aatccaagtg gccaagaggg
    14461 ctatgagatg attctaaaaa gccccttaga ccttcaggat agtcatcagg ctgcagacta
    14521 cgtctttgga gaccatagta ttgttgctgc tattgatggc tgggaggata acaaagaggc
    14581 ctttaaggtc gaccatgtct ttaccagtaa ggtctttacc attaacagct caaaggtgac
    14641 ctttgatggt ggtgaagcac cggttgtcag cgaccattat ggcctagagg ttgacctcag
    14701 ctggaagctg taacaaaaaa agccagcagg acttgataga ctgctgacac tgtaagaaac
    14761 agatggttat cttagctctt agaagtaagc ttatcgcaag gcttctaaga gcttttttgc
    14821 atttatattt catgagcata tgagaaagtt gcagacaaat gctggacaca taatcagact
    14881 gtgggctagt tacatcgtct gctctgattt gtgtcagata gtgatgatct gtgctgcctt
    14941 gtgattggcc agatatttac ctcatatcaa tagcagaaag tcaagtctcc ctcagcctat
    15001 ctcctagctt acgattgctg atcatcagtc agtctagcta caattacctg tgccaagcgc
    15061 tcaatatcag cactggtccc gcgtagttcg aaatctccca gcattggaaa gccaaagcgc
    15121 ttagcatact gcttggctgt tagacaatac tggtgattga agtttttgtt gccagagccg
    15181 ataatcccta aacaacgctt ggcattatca tgcgccgcga taaagtctcc cagcggattg
    15241 gtcaagattt caacctcccc tgagtcaatc ccgtttcctc cttcaagata ggtcggcaaa
    15301 atagcaacaa agctctcctt gactgaaaag gtttcgtgat gaagctcctt gatattgatt
    15361 gctttagtct gtatgtggtg cttttctgcc aggtattgcg acaagcgcct aacaaagctc
    15421 agggtattgc cgctaagact gataaaaaca agggtcaagt ctgtcataaa agactccttt
    15481 agcaagatta gtttcctaac cagcttagca caatacccct gaatacacaa ctcatatgac
    15541 aatgctctgc acgacaaacg cgcgaaacag tcatttccga atgatagtat agacttaagc
    15601 agatacattc accgtttttt ctatagtaaa agctatagaa aataagatat cttcttgaaa
    15661 tagctaaaca ttgacataca gaaagctttg ttttcttgct aaaaccctat catgcgtctg
    15721 ccgtgcaatg ctctgacagc tagcccacta gtcacatcac ataaaaaagg cttggtgaca
    15781 aggacggtaa gtccaaatca tcaagtcttt ttatggagag agcttagtgt tagctgttac
    15841 ccgaatcaag aggcccttgc tgctaatgct tgcgattttg ataggtcttt gggctttctc
    15901 cggtatgctt tttgaaaaat ttagaaaaat gtgagggatc agtgaagccc aacacgtctg
    15961 aaatgtgatt aatggcataa gcagagcgca gcaatgtctt agcctcttca attttcatgt
    16021 ttgaggtgta ttggtagatg gtcaagcctg tatcacgctt aaagatctgt ctcagcttgg
    16081 actcgctcat gttaaaatgc tgtgccagct cagcggttgt gacactctta tgcaggttga
    16141 cactgatata ttggataatg gcattaaccg taggagagac atgtttccag cggttgtccc
    16201 gcagctcact caccttttgg gtgtaaaaga ccagtgaggc atcacgaatt ttgagcacat
    16261 ctggcattga ggttgccagc tcgctgtctc tcatgaactc ctctcgtgaa tggtaggcat
    16321 cagcaatatc cataccagat tgaatggcaa tctgggctag tcgatcaaag gcaatgatag
    16381 aataattttt ttcagagcgc agcgtatcac cactcaccac agggataaag gtatttcgta
    16441 gactgaagat gatttccttg agcttgtgca catcaccctc ttgaacaatg ctagataaat
    16501 ttttctcata attgtagaga caaaccttag attcctgctt cttgacaaac atattggcct
    16561 tttgcacctc gatattgtcg gaaaaatccc taatatagtg acgtaaagga ggtgataaca
    16621 aatcctctat cttgccggaa aagaagtaat ggaccacaat caagaggtca cgaatagcat
    16681 tcaaaggata aacaggtaaa tgctttagcg cttggtaaag aatctcttct tcttccttag
    16741 tcaaatcctt atcagcaacg gccaccttaa aaaaggtctt atccaaaaca ttacagcgcc
    16801 aagggccaat taaaatataa tgatcctgat aacggtatat taaaaaaagc tcattatagc
    16861 ttccctgaaa gaaaagattg gttgcctgtt ccttgtccat ttgcctaagc actgcttgaa
    16921 aacgataata aaattcaaag gtatcatcat tccaaaagct ttctgtcacc tgatggtcct
    16981 tatcaaatac tgtaattgat aacttcaaac agccctgtag agattttact aacgacatag
    17041 tatccatgct aagcgtcacc cccttcataa tcctcacggt atcttattct atcttaaaat
    17101 ttaagaaaag caaggatatg cacttataat gaaaaaatag acataaaaaa caataatata
    17161 cattcttgct tattaaataa aaatgacaat gtactgcata aagaagttcc tgtcattaaa
    17221 ataaaagtgc catgaggtta taatagtatg gtaaaacaaa aaagtgtgcc cataacgggt
    17281 agagaggaat tgacatatgt ttttgagaaa taacaagcaa aaatttagca tcagaaaact
    17341 aagtgccggt gcagcatcag tattagttgc aacaagtgtg ttgggaggga caactgtaaa
    17401 agcgaactct gaggttagtc gtacggcgac tccaagatta tcgcgtgatt taaaaaatag
    17461 attaagcgat atagccataa gtggagatgc ctcatcagcc caaaaagttc gaaatcttct
    17521 aaaaggcgcc tctgttgggg atttacaggc attattgaga ggtcttgatt cagcaagggc
    17581 tgcgtatggt agagatgatt attacaattt attgatgcac ctttcatcga tgttaaatga
    17641 taaacctgat ggggatagaa gacaattaag tttggcttca ttacttgtag atgaaattga
    17701 aaagcggatt gctgatggag ataggtatgc aaaacttctt gaggctaaac ttgcagctat
    17761 taaatctcaa caagaaatgc ttagagaaag agattcccaa cttcgaaatc tagagaagga
    17821 aaaagaacaa gaactacaaa aagctaaaga tgagcgtcaa gctcttaccg aatcattcaa
    17881 caaaacttta tcaagatcaa caaaagagta taataaacta aaaacagaac ttgcaaaaga
    17941 aaaagaaaaa gcagctaaga tgactaagga attagcagat aagctaagca atgctgaagc
    18001 aagtcgtgat aaagcctttg cagtatcaaa agatttagca gataaactaa gtagtgctga
    18061 agcaagtcgt gataaagctt ttgcagtatc aaaagattta gcagataaat tggcagctaa
    18121 aacagcagaa gctgaaaagt taatggaaaa cgttggtagt ctagaccgct tggtagagtc
    18181 tgcaaaacgt gaaatggctc aaaaattagc agaaattgat caattaactg ctgataaggc
    18241 taaggctgat gcagagcttg cagctgcaaa tgacaccatt gcatcacttc aaacagagct
    18301 agaaaaagct aagacagagc ttgctgtttc agagcgtttg attgaatcag gcaaacgtga
    18361 aattgctgag ctacaaaaac aaaaagatgc ttctgataag gctttagtag aatcacaagc
    18421 taatgtagca gagcttgaaa aacaaaaagc agcatcagat gctaaggtag cagagcttga
    18481 aaaagaagtt gaagctgcta aagctgaggt tgcagatctt aaagcacaat tagctaagaa
    18541 agaagaagag cttgaagccg ttaagaagga aaaagaagcg cttgaagcta agattgaaga
    18601 gctcaaaaaa gctcatgctg aggaactttc aaaacttaaa gaaatgcttg agaagaaaga
    18661 ccatgcaaat gcagatcttc aagcagaaat caatcgcttg aagcaagagc tagctgacag
    18721 gattaagtca ttgtcacaag gtggtcgtgc ttcacaaaca aacccaggca ctacaactgc
    18781 taaagcaggt caattgccat ctactggtga gtctgctaac ccattcttca ctattgcagc
    18841 tcttactgtc atcgctggtg ctggtatggc tgtggtgtct cctaaacgca aagaaaacta
    18901 agctatttcc tctttcccca atggacaata gccgaaataa tagagcgact atcgttctaa
    18961 cacaaaagca acagtctcct gtctgttgct ttttgtgata ttagggctca tcagtctagg
    19021 ctaatggttt tctgcgcttt atctgcagct ttgaggattc cttcttttgc ttttacagtg
    19081 aaagtgttaa aataggaaaa acaactagta attgaggaag taaatggtta aagaaatcaa
    19141 tttatcagga gaggaagtag ttgcccttgc tgccaagtac atgacagacg gtgacgtcga
    19201 gcttgtgcaa aaggcgcttg attatgcgac agctgctcat ttttaccagg ttagaaagtc
    19261 gggggagcct tatattgtgc accctattca ggtagcagca atcctagcag acctgcattt
    19321 ggacgctgtg acagttgtct gtggcttttt gcatgatgtg gtagaggata ctgatattac
    19381 tctagaggac attgagtttg actttggtaa ggacgttcgt gacattgttg atggggtcac
    19441 aaagcttggt aaggtagaat acaagtctca cgaggagcag ctggctgaaa accaccgcaa
    19501 aatgctcatg gccatgtcaa aggacattcg tgtgattttg gtcaagctag ccgaccgact
    19561 gcacaatatg cgcaccctca agcacctccg taaggacaag caggagcgga tttctcgtga
    19621 aaccatggaa atctatgccc cgctagccca tcgcttgggg atcagtcgga tcaagtggga
    19681 gctggaggat ctagcttttc gctacctcaa tgagatcgaa ttctacaaaa tctctcatat
    19741 gatgagagaa aagcggcggg agcgcgaagc tttggttgat gatattgtca ctaagattaa
    19801 agcctacacc accgatcaag ggctttatgg tgatgtctat ggccgtccta agcacatcta
    19861 ctcggtttac cggaaaatgc gtgacaagaa aaagcgcttt gatcagatat ttgacttgat
    19921 tgcgatccgt tgtgtcatgg agacacaaag tgatgtttac gcgatggtcg gctatattca
    19981 tgagctctgg cgtcccatgc ctggccgctt caaggactac attgcagcgc ctaagaccaa
    20041 tggctatcag tcgattcaca cgactgttta cgggccaaaa ggaccgattg aaattcagat
    20101 tcggaccaag gaaatgcatc aggtcgctga gtatggggta gcagcccact gggcctacaa
    20161 aaaaggtatt cgtggcaagg tcaatcaagt cgagcaaaag gttggtatga attggattaa
    20221 ggagcttgtc gagcttcagg ctgcctcaaa tggcgatgct aagggctttg ttgactcggt
    20281 gaaggaggac atcttttcag agcgtatcta tgtgttcaca ccgacaggag cagtgcagga
    20341 attgcccaag gattcaggcc ctatagactt tgcctatgcc gttcacactc aggttggtga
    20401 aaaggcgaca ggagccaagg tcaatggccg catggtgccc ttgacagcca agttaaaaac
    20461 cggtgatgtg gtggaaattg tcaccaatcc gaattccttt ggtcctagtc gtgactggat
    20521 taagctcgtc aagaccaata aggctcgtaa caagattcgc caattcttta aaaatcagga
    20581 caaggagctg tctatcaata aaggacgtga gcttctggtt agttattttc aagagcaggg
    20641 ctatgttgcc aacaagtacc ttgagcgtaa gcgtattgag gagattttac caaaggtcag
    20701 tgttaaaagc gaggagtctc tctatgccgc tgttggcttt ggcgatatta gcccagtcag
    20761 tgtctttaat aaattaaccg aaagagaaag gcgtgaggag gagcgtgcca aggctaaggc
    20821 tgaagctgag gagctggtta agggcggtga ggtcaagcat gaaaacaaag agattctcaa
    20881 ggtccgcagt gaaaatggcg tgattatcca aggggcgtct gggcttctca tgcgtatcgc
    20941 caaatgctgc aatcccgtac caggagatgt gattgaaggc tatattacca agggacgagg
    21001 cattgctatt caccgcgcag actgtaataa catcaagagt caggacggct atcaggagcg
    21061 tctcattgag gttgagtggg atttggagca ttctagcaag gattaccaag ctgagattga
    21121 tatttatggt ttaaatcgta tcggcctgct caatgatgtc ctgcaaatcc tatctaacgc
    21181 caccaagagc atttcaactg tcaatgccca gccgaccaag gacatgaagt ttgccaatat
    21241 tcatgtgagc tttggcattc ctaatctggc tcagctgaca gctgttgttg aaaaggtcaa
    21301 ggcggttcca gatgtttaca gcgtcaaacg aaccaacgga taaaaaggag accaaccatg
    21361 aaaattgtga ttcagcgcgt caaggaagcc tcagtgtcga ttgatgggaa aatagctggc
    21421 gctattgatc aagggctgct gctgcttgtt ggcataggtc cagatgatca ggcagaggat
    21481 atagactatg cagtgcgtaa aatcagtcat atgcggattt tttcagaccc cgagggcaag
    21541 atgaaccgat ccattcagga cattgagggc agtgtcttgt ctatctcgca gtttacgcta
    21601 tatgctgaca ccaaaaaggg caaccgacct gccttcaccg gggctgctaa gcctgacagg
    21661 gccagccagc tttataacag cttcaacgct cagctagagc agcttgtacc ggttcagcga
    21721 ggggtctttg gtgcggacat gcaggttagt ctgatcaatg atggcccagt tacgattatc
    21781 ctagatacga agtatcgata actgcctagc gatcgatcgt ttgcttagga gagtcatata
    21841 aaggaaaaac aaaaagacga gtggtatgag aagcactcgt ctttgtcgtt tatgctgctg
    21901 tgttgaagct agctagggct actagtctta tttttgcagg tctttgtaga ctgcgatgaa
    21961 ttctgtctca gaaattgggg ttaagctgcc agtgaattgg taagaagtac catttttagc
    22021 ttggaaagta ttaggtaaac ctttaaggta tttgtcgata gtctcagtgg taattgcttc
    22081 gtgtgtttta aaggtgtatt cgttaatcag ctgctgctgt ttgtcctgtt ggtaaatagt
    22141 aactgaacga taggttgtgc tatagtcatc gttaatatcc ttagaaataa aataggtttc
    22201 tacaacagaa tctgaatgtg tcgcatagct aatgggattg ttgacgtcat actttgaatt
    22261 atatacttga gctatcctgt tagaatctat gatatagtta aagtcctcat cgcgatcagc
    22321 atggtagacc atgcgttcac tagctccact gtaaatctca ccgttatggc tttgatgagt
    22381 tatatcagga tcctgcgtga ctgttgtact gattcgcttg acgagctgat acccgtcttt
    22441 gaaagcctga gtggtttcaa aagccttttt agcagcttca aagagctcct cagaagagac
    22501 cctgctgcca tagtatctta acccggtaag tccttcttta ccaaggctgt cagttacatc
    22561 aacattaaca agctgcccat tgtctttttt gaggaattta acgtgctgtg tcacagctac
    22621 ggcatctgaa tcttggattg ggtttcctgc cttatctgtt accttaatgt ccttgagagc
    22681 taccttgcta actttttcca caaggacctg acccgtcaag atgtatgttt ggtctttttg
    22741 atgatactgt cctttgattg gtgtcgtaaa atggtctgtg ctaagtattt cagctgtaga
    22801 agcttttgtt aatttggcat ttttcaaact aatgacctta aagctttctg ctgaaggatc
    22861 tatgacgtct tgaactagct ttatcatctc atttgtggtg taggttttgc catattctag
    22921 tctaatatcc tgataatgtg gagatacgat ggtgtgatta gtgttatcta ctccagtgat
    22981 attgaccatg aggtacagtc ctgtggtttc ttgatagtct tttgaatgga ttggcttagt
    23041 ggtgtcctcg tatttatagt gatttgctac cctactagag cttgaccatg cccacccaac
    23101 tttgtaatgg tttgctttaa cggcaggtgc tcccaaggtc atggtgaata gtccaatgac
    23161 tacagttcct atttctaaag gtgttttccc aaggtgatac agtctttttg aagtcaacat
    23221 atttcaaacc tccctaaatc ctgtcagtct ctatagttat aaaaatacag agaatcgtta
    23281 gaagaattaa tgtttcatgc cggcaagatg agtgtaacaa aagattggtg ccgatacaag
    23341 aagatggaga ttagagcatc tggtttcaat gagagttaca taatagcaga aggttttttc
    23401 actatgagag ctaatcgtct taaaatggta taatagcaag tgaataggct atctaactgg
    23461 tttaacagcc atttttagag aagcttaata gtattgctga taagtgactc gtatctccat
    23521 attgcttttc aaaggctatg ttagctatga taagcgtgac caggctatcg gaaaatccag
    23581 tgttcttaaa ggctttgaag ctctggcttt gaaccttagc tctggtgttt ctatgaaaat
    23641 gacttgggcc ttgtaccaga taagaatgaa gtcaaattga ggttttttga caaaatgttt
    23701 gagtaaatac aagttcatag aagtctaatg tataaaaata caattgtatc gccataatct
    23761 gaatgaccaa accattaaaa aaataaaatt tttaaacatt ttggaaaacg ctttcaaaac
    23821 taaaaagaac tgtcctatag tcattgctta gcattaaagc aaggtgtgaa atgttatcat
    23881 atggagaaat aggctgtctt gtgctgtatc tgtgccaaaa aagaatgctt gtttttgtga
    23941 tataatgtga ctaagaaacc tgaaaggaat gcttatggca ttaaaagact attttcctga
    24001 tatgcaagag ggtgcatttc ctctggctga ccaagattgg attagcgttg aggttgggga
    24061 gcagtacctc catttcccca aatccagctt gtcagagcga gagcagcttt tgcttggttt
    24121 ggggcggcag cgcaaagagc cgtccaagga tcagaaatct ccttggtatc attatttgat
    24181 tctgggccaa ggggagcagc cggaggagtt tcagggttgc cagttcatct atatcaacca
    24241 tcaatgtcct ttagcaggtg atttgattga gcttctaaag gggatcatag agggagttga
    24301 ggctgttttg cccattagcc agaccaggac agcttttttg gtctgtcacc atagccgttc
    24361 agaccttttt cagctcttag caaatttatt gcccacgatt gagagcgatt ttggtttggc
    24421 cttgatgatt tttatcggta atggctggta tcaggtgtca ggaaatgcct tgagagacta
    24481 ttttaaggaa gaaaatgctg tgtttacagc ttatcttgct gagcactctg ccagtcgctt
    24541 gctgaccttt tcagaggtca tgctctggtc actcttagca aacagtggtt tgccagcctt
    24601 gtcaaagcat tttagtcagc tgcttttagc caataaagag gtcatggatc tggtgctcgc
    24661 catgtggcag gagcatggca acctggtaca gacagcccag cgcttgtata ttcatcgcaa
    24721 ttcgctgcaa tataagctgg ataagtttgc tcagcagtca ggtctctatt taaagcagct
    24781 agatgacttg gcctttgctt atctatttat actgaagcat tagatttgtg cagggtgccc
    24841 aaagacattt gggcgttttg tctatatgat gaaaacgcta tctttgctat aataaaagca
    24901 tcaaataaaa agtgtcaggg ttgctagcat tgcagtcagc tagcagccta tctgacccat
    24961 taggagtaac gcatggttga attaaactta aagcacatct ataagaaata cccaaatacc
    25021 acacactatg ctgttgagga tttcgattta gacattaagg ataaggaatt tatcgttttt
    25081 gtagggcctt caggctgtgg taagtcaaca acgcttcgta tgattgctgg gcttgaggat
    25141 atttcagagg gtgaattgaa aattgacggt gaggttgtga atgacaaatc accaaaggac
    25201 cgcgatatcg cgatggtttt ccaaaactat gccctttacc cgcatatgac cgtttatgac
    25261 aacatggcct ttggtctcaa gctacgtaaa tacaaaaaag atgatattga tcgtcgtgtc
    25321 aaggaagcag cagaaatcct tggcttgaca gaatttttag aacgtaagcc agcagacctt
    25381 tctggtggtc agcgtcagcg tgtggctatg ggacgtgcta tcgtgcgtga tgccaaggta
    25441 ttcttgatgg acgagccttt gtcaaaccta gacgctaagc tgcgggtgtc aatgcgtgct
    25501 gaaattgcga aaattcaccg ccgtatcggc tcaacaacaa tctacgtaac gcacgaccag
    25561 accgaagcga tgaccttggc agatcgtatc gttatcatga gtgccactaa aaaccctcaa
    25621 ggcaacggta caatcggaaa gattgagcag gttggctcac cacaggagct ctataaccta
    25681 ccggccaata aatttgttgc aggctttatt ggaagccctg cgatgaactt ctttgaggtg
    25741 gttgtcaagg acggtcagat catcagtgag gacgggcttg atattgctat tccagaaggt
    25801 caggctaaaa tgcttgaagc agctggctat aagggcaaga aggttatttt tggtatccgt
    25861 ccagaagata tttcaagcaa ccaaatcgtg catgacacct atccaaatgc caatgtcaca
    25921 gcagaggtct tggtttctga gctgcttgga tctgaaacca tgctttatgt taagcttggt
    25981 caaacagagt ttgcttcacg agttgatgcg cgtgacttcc acaatccagg tgaaaaggtt
    26041 agcttgacct tcaatgttgc taaggggcat ttctttgatc tagaaacaga gcaagctatt
    26101 cgctaataac acctcctaga ataaaatcct catcttgctt gaggattttt taacaaaaga
    26161 aaatgcaagc gattgcgcta tcaaaaagaa aaagggattt atcataaaga caacagatgt
    26221 tctgtagtgc taggcgatca taatgatggc acgaaatagc aggagactgt ttagtaataa
    26281 ggagatatga tggaaaaaca ctggtggcat aaagcgacaa tttatcaaat ttacccaagg
    26341 tccttcatgg atacaagtgg gaatggtatt ggtgatttaa aaggaatcac aggtaagctg
    26401 gattatctac aggagctagg gatcacagct atttggctgt ctccagttta tcaatcacca
    26461 atggacgata acggctatga tatttcagac tatcaggcca ttgcagctat ttttggtgat
    26521 atggctgata tggacgagct gcttgatgag gccaagcagc gggggatcaa aatcatcatg
    26581 gatttggttg tcaatcacac ctctgatgag cacgcttggt ttgtggaggc aagagaaaat
    26641 cctgacagtc ctaaacgaga ttattacatt tggcgtgatc agcctaataa tctcatgtcg
    26701 atcttttctg gctctgcttg ggaatatgat gatgcctctg ggcagtatta tctgcacata
    26761 ttcagtaaaa aacagcccga cttgaattgg gaaaatgctg aattgcgtca aagcatttat
    26821 gacatgatga atttctggat tgataagggg ataggtggct ttcgcatgga cgtcattgac
    26881 ctgattggta agattccgga ttctgaaatt acaggcaatg gcccaaggct gcatgaatac
    26941 ctcaaggaga tgaaccaggc aagctttggg aatcatgacc tgatgactgt tggtgaaaca
    27001 tggggcgcta caccggaaat tgctcgtcag tattcacgtc ctgaaaataa ggagctgtca
    27061 atggtctttc aatttgaaca tatcggcttg cagcataagc caaatgcttc taaatgggat
    27121 tacgcagctg agttgaatgt tccggctctc aaggagattt ttagcaagtg gcagacagag
    27181 ctaaagctag gtgaaggctg gaactccctt ttttggaaca atcatgactt gcctcgtgtc
    27241 gtctccattt ggggaaatga tacagtatat agagagaagt ctgccaaggc aatggctatt
    27301 ttgctgcatt taatgcgtgg gacaccttat atttatcagg gtgaagagat tggcatgacc
    27361 aattacccct ttgagcgctt gagtgatgtg aatgatattg aatcactgaa ttatgccaag
    27421 gaggctatgg ctaatggcat gtcagaggag gctgttcttg attgtatttg tagggtgggt
    27481 cgagacaatg caagaacacc aatgcaatgg agcagtcaaa agaacgccgg cttttcaact
    27541 gctgatcaga cctggctgcc tgtcaaccca aatcatcaag agattaatgt ggctagtgct
    27601 ctagctgatc ctgattctgt tttttacacc tatcaaaagc ttattcagct gcgtcagaca
    27661 caggattggc tggtggaggc agattatcag ctgctggaaa catcagataa ggtttttgcc
    27721 tataagcgtc agcttggtag agagacttac cttgttgttg tcaatctgtc taatcaagag
    27781 cagttttttg aagaaagtct tcataaggcc caagtgatta tcagcaatac cgatgtgcag
    27841 gcagtcgtag aaagtcaaca gctggagcct tgggacgcct tttgtgttaa gcttgatgag
    27901 accttgtagc ctagctgctt gctgtgcctc agctcaataa tcgtagcgat tctttgagaa
    27961 ttttgacaaa ttgctgtatg attagtagaa gaattagata caaaagagga ggctgagatg
    28021 accgttgaag aaaccatgac ctttgcaaaa agcattgcag catttagata ggtagagatt
    28081 agtgaggtag tcactaggct agcagcaggt gaggacatca ccgtcttttt aggcagagcg
    28141 acctgtcctt attgtcgtcg ctttgcaccc aagctagcaa gcgtagcaag gcaggagcat
    28201 aaggatattt tctttgtaga tagtgaagac tcaacagagc ttgcagacct gcaggccttt
    28261 cgtgagcgct atgggcttgc tactgtgcct gccctgctca ttagtcgtca tcaggaggtc
    28321 aaggcagtct gtgattctag cttgactgag gaagccattt tggctttcct agagcagtga
    28381 cagacagcta attatctggt gcaagtaata gaaatgtaat cagtcatgtc ttgctatgtg
    28441 agtccaaatc tgctatagta ggacatgact tttagacgaa ataaggagat attatgggct
    28501 taccaacaat tttaatgttt gttgtcatga ttggtttaat ttggtttatg cagcgtcagc
    28561 aaaaaaagca ggcgcaggag cgccaaaatc agcttaatgc gattgaaaaa ggcgatgaga
    28621 ttgtgacgat tggtggcatg tttgcagtgg tcgatgaggt tgatttagca gcaaagcgaa
    28681 ttgtcttaga tgttgatggt gtctatctgc catttgagct atcagcgatc aagcgcgtgg
    28741 tcgaaaaagg aagtgcagtg acatcagctg atgtggatac gacagagact gcagttgatg
    28801 acacagcggt tgaggcttca gacgaagctg aatcagctat tgagacaaat taagaaaatg
    28861 aggtctgaag cattagtgtt tcagactttt ttaggtgatg atagcaggta gccagacaga
    28921 gctgtcatgt gctatggaaa tatcgtctac aacgagaaaa agcgagccaa accgcatgaa
    28981 atatggtaaa atatgaggta agtatgcttg tgaataagga aaaaacatgt ttggattaaa
    29041 agcgaagtca aaaaaaatcg ttttggatag gattccaaag cacattggga tcatcatgga
    29101 tggtaatgga cgctgggcga aaaaacgctt aaagccgcgt gtctttggac ataaggcggg
    29161 tatggacgct ttgcaggagg taacgattgc agcttcagat ttaggggtta aggtgttaac
    29221 agtctatgcc ttttcgacag aaaattggtc aagaccacaa gatgaggtga gcttcattat
    29281 gaacctgcct gttgagtttt ttgataagta tgtgcctgag ctgcacaaaa ataatgtcaa
    29341 ggtgcagatg atcggtgaga ccaaccgcct acctaaggat acactaaagg ccttggaagc
    29401 agctattgct aagacaaggc aaaatactgg cttgattcta aactttgctc ttaattatgg
    29461 gggtcgcgcg gaaatcacca atgctgtcgg tctcattgct caagatgtcc tagacgccaa
    29521 gctgaaccct ggtgacatta ccgaggattt gattgccaac tatttgatga cggatcattt
    29581 gccctatctc tatcgcgatc ctgaccttat tatcagaacg agcggtgaat tgcgcttgag
    29641 taattttatg ccttggcaat cagcctatag tgagctttac tttacgccgg tgctgtggcc
    29701 tgattttaaa agagctgaac tactaaaggc catagaggat tataaccatc gtcatcgccg
    29761 tttcggtgct atttaaggag agagtatgag agaacgtttc atttggggtg gtgttgcagc
    29821 tgctgttttc ctaccctttt tactcattgg cagcttaccc tttcaattgt ttgtaggtgt
    29881 gcttgccatg attggtgtat cagagctgtt aagaatgaag aggcttgagg tcttttcctt
    29941 tgagggtgtt tttgccatgc tagcagcttt cgttttgaca gtgccgttgg atcattacct
    30001 gacctttttg ccgatggacg ctagttttgc ttgttacggg ctgttggtgt ttttcctttt
    30061 agcaggaata gtgattagca gcgattctta tggctttgag gatgctagct ttccgattgc
    30121 agctagctta tatgttggta ttggctttca taatctggtt aatgcgcgaa tgacagggat
    30181 agacaaggtt tttctggctc tttttattgt ctgggcgact gatattggag cttacttgat
    30241 tgggcgccga tttggtaagc gaaagctcct gccaaaaata tcacccaaca aaacaattga
    30301 gggcagcctt ggtggtatag tcagtgcggt gcttgtttcc tttgtgttta tgctctttga
    30361 taaggctgtt tatgctcctc atcattttgg aacaatgttg attttggtgg ctcttttttc
    30421 tatttttgct cagtttggag atttggttga aagtgctgtc aaaagacatt tcggagttaa
    30481 ggactcaggc aaattgattc caggccatgg tggtatttta gatcgttttg attcgatgat
    30541 ctttgttttt cccattatgc atctatttgg gttattttaa agctcattat caatagactg
    30601 aaaggaaatc tatgttagga ataattacct ttattattat ttttggtatt cttgtgcttg
    30661 tccatgagtt tggccatttc tattttgcta aacgatctgg tattttagtc agagagtttg
    30721 ctattggcat gggaccaaaa ctcttttcgc atgttgatca gcaaggaacg ctttacacga
    30781 tccggctatt accgcttggt ggctatgtgc gaatggcagg ctggggtgat gacacaactg
    30841 agataaaaac aggaacgcct gctagcttaa cgcttaatga tcagggcttg gtcaagcgga
    30901 ttaacctgtc tcagagcaag cttgatccga ctagcctgcc tatgaatgtg actgcttatg
    30961 acttagaaga taagttgacg attacagggc tggttcttga tgagatcaag acctattcgg
    31021 tagaccatga cgcgaccatt gtcgaggagg acggtacaga gatccggatt gcgccgcttg
    31081 atgttcagta tcaaaacgca agcattggcg gtcgtttgat caccaatttt gcaggaccta
    31141 tgaataattt tattctaggt attgttgtct ttattttgtt tgcctttgtt caaggtggtg
    31201 tggctgatta tcatagcaac catattcgtg tggtggaaaa tggcgcagca gccaaggctg
    31261 gtattagaga caatgatcag attttagaga ttaatcatca aaagattaat gactggtatg
    31321 agttgacgca ggccgttact gattcagcag cagatgttaa ggctaagggc aagctagaga
    31381 ttacctatca gacaggtgat caggttaaga ctatagcact gaagcctgaa aaaaaaggcg
    31441 atcagtacct tattggtgtc cagtacccac taaaaacaag tctgacagac aagctaatag
    31501 gtggctttga gatggctggt aatggtgctc tagtgattgt cactgctcta aagagtttga
    31561 ttacctcctt tagcctagat aaattaggtg ggccagttgc catgtatcag atgtccaatc
    31621 aggcagcaaa gaatggttta gagtctgtct tgtccttgat ggcaatgctc tctatcaatt
    31681 tagggatttt taatttgatt ccgattcccg cactagatgg tggtaagatc ctgatgaatg
    31741 tgattgaagc acttcgtcgt aagccattaa agcaagagac agagacttat attacccttg
    31801 caggtgttgc gattatggtg gtactcatga ttgcagtgac ctggaacgat attatgcgag
    31861 cctttttcca aggctgatgg tctctctcat ttaaaggaga gcctaaaagg cttaatgtaa
    31921 cagaaataac aagagatata gtgtcattat tgtggttcta agaccttgca aatgcagcaa
    31981 aagcttagcc aatatagctc attttgtctc ttttttagaa atgaattctc aacgaaagga
    32041 aagagagctg ttgaccaagc tgggctaagg cctacagctg aaatcaaaat gctagacctg
    32101 ctattagtct aagggcgttt tgagctgctc tctatagctt attttaatga aacaaagtaa
    32161 aatgcttatc ccaaccctgc gcgaaatgcc aagtgacgct caggtaatca gtcatgccct
    32221 catggtgcgt gcgggctatg tccgtcaggt atctgccggt atttatgcct atttgccatt
    32281 agctcatcgt acaattgaaa aattcaagac gattatgcgg caggaatttg acaaaattgg
    32341 tgctgttgaa atgctagcac ctgccctttt aacagctgac ctctggcgtg aatcaggccg
    32401 ctatgagact tacggtgagg acctttacaa gctaaaaaac cgcgacaaat cagactttat
    32461 cttaggtcct acccatgaag aaacctttac tacactggtg cgtgatgcgg ttaaatccta
    32521 taagcagctg ccgctcaatc tgtatcagat tcaatccaaa tatcgtgatg aaaagcgtcc
    32581 tcgtaatggc ctgcttcgca cacgtgaatt tatcatgaag gacggctata gctttcatca
    32641 aagctatgat gatttagatg tcacctatga cgcctatcgt caggcctatg aggctatttt
    32701 taccagagca ggcttggatt tcaaaggaat tatcggtgat ggtggtgcta tgggtggtaa
    32761 ggattcgcag gaatttatgg ctatcacacc ggaccgtact aatttagacc gctggctggt
    32821 cttagacaag tctattccgt cattggctga cattccagag gaggtcttgg aagagattaa
    32881 ggccgagctg gcttcatggc tggtttcagg agaggacacc attgcttatt caagtgaatc
    32941 aagctatgct gctaaccttg agatggcaac cagtgagtac aagtcctcat caaaggtaac
    33001 agccttagat gatctcgtcg agattgagac accaaattgt aaaaccattg atgaagtggc
    33061 ggcctttctt gacgttgctg agcatcaggt cattaaaacc ctgctcttta tggtggacca
    33121 tgagcctgtg cttgctttat tggttggaaa tgaccagatc aatgctgtca aattgaaaaa
    33181 ccacctcggt gcagacttct tagagccagc tagcgaggag gaggcgcgtg ctatcctagg
    33241 tgcaggcttt ggttcacttg gtccagttca tttgacagat ggtatccgta ttgtggctga
    33301 tcgtaaggtc caagaccttg ctaatgctgt agctggagcc aataaagatg gttatcacct
    33361 gactggtgtc aatccaaatc gtgatttcca agcagagtat gctgatattc gtgaggtaaa
    33421 agagggagag acctctccag atagacatgg cgtgctgcag tttgccagag gtattgaaat
    33481 cggtcatatc tttaagctgg ggacccgcta ttctgatagc atggcagcta atatccttga
    33541 tgagaatggc agagcagttc cgattgtcat gggctgctat ggtattgggg ttagtcgtat
    33601 cctatcagca gtcattgagc agcatgctcg tctctttgtc agcaagacac caaagggtga
    33661 ttatcgctat gcttggggga ttaatttccc taaagagcta gctccgtttg atgtgcattt
    33721 gattaccgtt aatgtcaagg atcaggaggc gcaggacctg acagaaagag tagaggctag
    33781 tctgatggcc aagggctatg atgtcctcac tgatgaccgc aatgagcgtg tcggctctaa
    33841 gttctctgat agtgatttga ttgggcttcc gattcgtgtg acgattggta aaaaagcagc
    33901 tgagggcatt gttgagatca aaatcaaagc aacaggtgac agcattgagg tgcacgctga
    33961 tagcttgatt gaaactcttg acattctcac aaaggacaac taatgatatg aggtcaacga
    34021 tggttgatct ctttttgtat gctataatga aagcatgaca attgaggaat tacagcagct
    34081 ggtgctagca gatcatgagc taatgactat tctaagcatt atagagacct tgcctttaaa
    34141 ggattgttgg ctggcagcag gtgcaattcg gaacgctatt tggaatcatt tagcttatgg
    34201 gataggcttt gatccgctga cagatgtaga tgtggtcttt tttgaccctg agatctctta
    34261 cgaagctgag cagctgctag aagagcagct taagtgtgct tatcccatgt accaatggga
    34321 ggttcgcaat caagcctata tggcagcaca taaccccaag acgcctcctt atcgatctag
    34381 tcaagacgct atcacaaagt atccggagcg ctgtacagcg attgctgtta gacttgtagg
    34441 aggacagcta gaggtttttg ctccctatgg tttagcagac attagtcact ttgtctgtcg
    34501 gccaacaccg cattttttag aggattcaga gcgtatggac tgctataggc agcgcctagc
    34561 aaagaaggac tggcacaaga aatggccaca gctgacctac cacgactgct aagtcagagg
    34621 aaacaaagca ggctaggagc tccgtacagc caagcaatta gtccgctccc agacccgtta
    34681 gctacagctc tcacctagtc aaaacaagca catgaacaga tcattggcag atagccttgc
    34741 ctttgcagat attgtcacac cctatttagc tgtaccatgt gtcttatgat aggcgtgata
    34801 gtgctgtcag aagcgccagc tgagccagaa aaagcgttaa gcctacagca aggggctttt
    34861 aacctttggt atgttgtctt gtaggagagg tcgaaaatga tcactattta tgataaaata
    34921 gaccctaaga aaatcaggag aaagctatgt cagatttatt cggtaaattg atggaacaaa
    34981 ttgaaatgcc acttgagata agacaatcaa gtgccttttc gtctgctgat attatcgagg
    35041 tcaaggtgca ttcagtgtct cgtctgtggg aatttcattt ttcctttgca gaggttctcc
    35101 cgatagagag ctatcgagag ctgtcagata ggcttgtgag aacctttgag gcagcagata
    35161 ttaaggtaac atttgacatc aaggcagaga caattaatta ttcggatcag ctgctgcaag
    35221 cctactatca agaagcattt gagcatgagc cctgtaatgg ggctagcttc aagtcatctt
    35281 tttctagact tcaggtcagg tatgaccatc atcagctgat cattatggca cctgactttg
    35341 tgaataatga tcactttagg aaaaatcatt tacccaatct ggcagctcag tttgagcgct
    35401 ttggctttgg gaggctagcg attgatatgg tgtctgatca ggagatgaca gaccatttga
    35461 caaaggactt tgagaccaac cgtcaggctc tggtggaaaa ggctgtacag gataatatcg
    35521 cagcacagca atcattggag gccatgcagc caccagctga ggaggcagca ccaagcccaa
    35581 gccttgacta tagagagcgt atggctcagc gccaagcaag ctttgataag gcggtcatta
    35641 caccaatgat tgaggtggat acagaagaaa atcgcattgt ttttgaagga atggtctttg
    35701 atgtggagcg caagacgaca agaacaggcc gccatatcat caacttcaag atgacagatt
    35761 acacctcctc ctttgccatg caaaaatggg ccaaagatga cgatgagctc agaaaatttg
    35821 atctgattgc gaagggagct tggctgcgcg ttcagggaaa tatcgaaaac aaccccttca
    35881 ccaagagcct aaccatgaat gtgcagcagg ttaaggcgat tgttcaccat gagcgtaagg
    35941 atctcatgcc agaagggcaa aagcgtgttg aatttcatgc acacactaat atgtccacaa
    36001 tggacgctct accgacggta gaagacctga ttgatacagc agccaggtgg ggacatcagg
    36061 cagtagcgat tactgaccac gctaatgttc agagctttcc gcatggctat catagagcac
    36121 gcaaggcagg aatcaaggca atctttggct tagaggccaa tattgttgag gataaggtac
    36181 ctatttcctt caatcctgtc gctatggacc tgcatgaagc cacctatgtt gtctttgacg
    36241 tggagaccac cggcctttct gccatgaaca atgatttgat tcagatcgca gcttccaaaa
    36301 tgttcaaggg aaatatcatt gagcagtttg atgagtttat caatccaggc caccccttat
    36361 ctgcttttac aacagaattg acagggatta cagataatca tttggtagga gctaagccta
    36421 tacagcaggt gttagaggca tttcaggcct tttgtcaggg cactatccta gttgcccaca
    36481 atgctagctt tgacgtggga tttatgaatg ccaactacga tcggtatggt ttagcaaaaa
    36541 tcagccagcc agttattgac accctggagc ttgccagaaa cctgtaccct gagtataagc
    36601 ggcatggctt gggccctttg actaagcgct ttcaggttag ccttgagcac catcacatgg
    36661 ccaattacga tgctgaagca acagggcgtt tgctctttat cttcctaaag gaagctagag
    36721 aaaagcatgg gattacaaac ctgcttcagc tcaatacaga cttagtggca gaggattcct
    36781 ataagaaagc acggatcaag cacgccacga tctatgttca aaatcagcta ggtctcaaaa
    36841 acatgtttaa gctggttagc ctttcaaatg tgaaatattt tgaaggtgtg cctagaattc
    36901 caagaaccgt ccttgatcag catcgtgaag gcttgctgct tgggacagcc tgctcagacg
    36961 gcgaggtctt tgacgccgtt ttgacccaag gaattgacgc tgctgttgat ctggccaaat
    37021 actacgattt tatcgaaatc atgccgcctg caatttacca gcccttggta gtccgagagc
    37081 taatcaagga tcaagcagga gttgagcaga ttattcgcga tttgattgag gtcggccgca
    37141 gagctgaaaa gcctgtccta gctactggaa acgtgcacta cattgagcca gaggacgcca
    37201 tctatcgtga cattatcgtt cgtagtctag ggcaaggtgc cctgattaac cgtactattg
    37261 gccgcggaga ggctgccaag cctgtcccgc taccagaggc tcattttaga acaaccaatg
    37321 aaatgcttga tgattttgcc tttttaggtc aggacttggc ctatgaggtt gtggtgcaaa
    37381 atacccaagc ccttgctgat cgaattgaaa aggtggaggt tgttaaggat gatctgtaca
    37441 ccccatatat tgataaggca gaagaaaccg ttgctgagct gacttatcaa aaggcctttg
    37501 ctatctatgg caacccactt ccagatatca ttgatctgcg cattgaaaag gagctaacgt
    37561 ccattttggg aaacggcttt gcggtgattt atctagcctc acaaatgctg gttaatcgct
    37621 ctaatgagcg tggttatctg gtaggctcac gtggctctgt tggttcaagc tttgttgcga
    37681 ccatgattgg catcacagag gtcaatccaa tgccgcctca ttatgtctgc ccaagctgcc
    37741 agcagtcaga gtttatcaca gatggctcgg tcggctctgg ctatgatttg ccaaacaagg
    37801 cctgtcctag atgtgggacg ctgtacaaaa aggacggaca ggatattcct tttgaaacct
    37861 tccttggctt tgatggtgat aaggttccag atattgattt gaacttctca ggagatgatc
    37921 agcccaatgc ccacttggac gttcgtgata tcttcgggga agaatacgcc tttcgtgcag
    37981 gtactgttgg tactgtcgct gaaaaaacag cctatggctt tgtcaagggc tatgagagag
    38041 attatggcaa gttttaccca gatgcagagg ttgatcgtct agctgctggt gctgctggtg
    38101 ttaagcggac gactggtcag caccctggtg ggatcgttgt tatccctaac tatatggacg
    38161 tttatgattt tacacctgtg cagtttccgg cagatgatgt gacagcctca tggcagacga
    38221 cccactttaa tttccatgat attgatgaaa atgtcctaaa gctcgatgta ctcggtcatg
    38281 atgatcccac catgattcgt aagctgcagg atttatcagg tattgatccg attactattc
    38341 cagcagatga tcctgacgtg atggcacttt tttctggaac agaggtgctc ggagtgactc
    38401 ctgaacaaat tggaacacca acaggtatgc ttgggatccc agagtttgga acgaactttg
    38461 ttcgtggcat ggtgaatgag acccacccaa cgacctttgc agaattgctg cagctatcag
    38521 gtctatcgca tggaacggac gtctggctgg gtaatgctca ggatctgatc aaagaaggca
    38581 ttgccaccct aaaaacagtt atcggttgtc gagatgacat catggtttac cttatgcatg
    38641 ctggtctaga gcctaagatg gcctttacca tcatggagcg tgtgcgtaag gggctctggc
    38701 taaagatttc cgaggaggag cgcagctcct atatcaaggc catgcggcaa aacaacgtcc
    38761 cagactggta catcgaatcc tgtggtaaaa tcaagtacat gttccccaag gctcacgctg
    38821 ccgcctatgt tttgatggca ttgcgagtgg cttatttcaa ggttcatcac cccatcatgt
    38881 attactgtgc ttatttctct attcgtgcca aggcctttga gctcaaaacc atgagtggtg
    38941 ggctagctgc tgtcaaggct cgcatggagg acatcagcaa caagcgcaag cgcaatgaag
    39001 cctcaaacgt tgaaaatgac ctgtttacca ctttagaaat tgtcaatgaa atgcttgaga
    39061 gagggtttaa gtttggcaag ctagaccttt acaagagcga ggcaactgag tttcaaattg
    39121 aaggggatac cctaattcca ccttttattg ccttagaagg cttgggagaa aacgttgcta
    39181 gacaaatcgt caaggctcgc caagatggtg aatttctatc aaaaatggaa ttacgcaagc
    39241 gtggtggtgc ttctgccact ctagttgata agatggacga gctgggcatt ttaggaaata
    39301 tgccagatga caatcagctg agtctatttg atgacttttt ctaagattgc acagccctaa
    39361 tattgtctat gttagcttgt catacagtga agagcagggc aggaaggctt cctgtcctct
    39421 ttttgtcaat acgcaaagaa agcccaaaaa agaacgagga aaagcatgaa tgaattagac
    39481 aaaaatcctg ccttaaaggc aatggttgtt tttagaaaag cacagcgtac cttagatgct
    39541 caaagctccg ccttttttca aaaggccaat ctgactccta cccaatttag cgtcttagag
    39601 gtgctttatt ccaaaggaag catgagaatt aacaagctca tcggttctct cttggcaacc
    39661 tctggcaata tgaccgtagt gctgaaaaat atggagagaa atggctggat cagccgctgc
    39721 caagatgcta aagataagcg tgcctgcttg gtacagctaa cgccagaggg caaagccttg
    39781 attgagacta tcctacctga gcatatcaaa cgtgttgaag cccttttttc agtgctgaca
    39841 gagactgagc aaaaacaatt gattacgctt ttaaagaaat ttaaagaact ctaagcaaat
    39901 ggctttacag gatctcccaa gtaggatata atcactacat agtacaaaaa gatactaact
    39961 agtcataata agtcatcaag acagcagatg gctagttacc agataatcaa tgggagacaa
    40021 agcatgaaac aaattttaat cattaatggt tcattacgga caggttcatt taatcatcag
    40081 cttgctcaag cggctgagca gctacttgaa ggcaaggcag ctgtatctta cttggactgg
    40141 gaacaggtac ctatgtttag tcaggattta gaagcaagca cccctgagtc agtggcaggc
    40201 gtacgagaag ccattcaagc agcagatgct atctggattt tttcacctgt ctataatttt
    40261 gcaatcccgg gctctatcaa aaacctatta gactgggtat cacgcgccct tgatttgtca
    40321 gacccatcag gaccatcagc aatcaatggt aaggtagtta ccgtatcatc tgttgctaat
    40381 ggtgggcacg agcagctatt tgcgcaatac caggacctgc tgccctttat ccgtacgaca
    40441 gtagttggta actttaccaa agccgctgtc aatccagaag catgggcgac aggtgttctt
    40501 gatatttctg aggaaacaag gcaaagcctt gcagcacagg cagaagccct tcttgaagcc
    40561 attcactaag actctctgag cattaaacag ataaagctgc agctaggatc aaaaagcagc
    40621 tagacacata aaaagagctt aaaccagaaa tgtacggcac tccaaaagct agacaaaaac
    40681 tctagcgatt ggggtacagg tcaaaacggt tttaagctct tttttagact tattttatag
    40741 tagtaactta attaagaatt agcataccct ctttagcctc aaaggggttt ttcgcattaa
    40801 tacggtcata gaataagaca ccattaatat gatcaatctc atgctgaacc acgatagcat
    40861 tgtagccctt tagcttaatg cggtgctttt cattgtgctt atcgtaatat tccactgtca
    40921 cacgcgcatg acggacgaca tagccttcca ccacacgatc aacagacaaa cacccctcac
    40981 cgtcagcaag agcagcgtct tgaacagaat gagacacaat tttaggatta tagagcactt
    41041 cctccatgct gtaagcctcc ttaggtggat tgccctcgct gtcttcagga tttggaacca
    41101 gaacagcgat gatacgcttt gacacatcaa tctgaggtgc tgctagacca actcctgctc
    41161 gaagccctaa tttttctccc atgacagggt cttgagaatg ctttaaaaat tgcatcattt
    41221 tttcacctaa aatgatgtca tcatcactaa gaggaaactc gacctcctta gccacagcac
    41281 gaagcgtagg attgccttcg cggataatat cattcatatc aatgagatgc tgtgctttaa
    41341 ttaatttatc ttgtgcagac attttgcctc ccttttttta tatttgataa tggctttact
    41401 atatcacaaa atccttattt ttaaaagata aggcaggcca gtgatgacga tattagctaa
    41461 ctctatcaga tatattaaat tatttaaaaa atagttcgtt aattagcacg acatatatat
    41521 aagaaataca caggaattct aataattaat agataaaaaa tgataatcgt tcgtaaataa
    41581 atcaaacatc taatctaaaa aaattatatt gttctgattg ttcggtaatt aaagcaatag
    41641 cgcttgtcga aaaactaatg ttctcttaat atcaggtagc catgccaagg gttttgtgtt
    41701 aaagtatagg acgttcaaaa aatgaaatgg agagactaat gagaacacaa ttgaaaaaat
    41761 tgctggcagg aacagcagca ggtaccctgc tgctgtttaa cctgacctgc ggaatgatta
    41821 atgcttttgc agagcagtat tacgggtgga gtgacgggag tagcagctat ccgagtgctt
    41881 tgtatgttac accggtagga gatactacga aaaagatagc tattcctgtt tattgctttg
    41941 actataagtt tcaggagcca cttgcttgga aagaaataac tcaaccgtca cacttgattg
    42001 tctatgataa gtatgatggc aaaaatttga tggcagcact ggttgaaaaa cctaatatgg
    42061 taagctatga gactaaaact aaacttcaaa cacttttaaa gacaaagtca aatctaataa
    42121 ctgcaatttt aagtagaggt tatccaaaca aaagtttttt tgataagtat aaaaaattaa
    42181 ctgatgaaga taaaagacga gtgacacaat gtgctctttg gtatcatact gacaatattt
    42241 cagaacaaga tcttatcaca aaacatttgg atggggattc aggtgaaaaa agtcaagcgc
    42301 taaaggagtt aataggggtt gtaaaaaata cttctaatga gttaggagag ggattaacct
    42361 tctatactcg ttataatgat agatatggtc ctaaatatca aaacctaata ggctcaatta
    42421 ttgttcccga agagcctcag aatgatcttg aaattggtgg tggaaatgtt attgatttaa
    42481 actaccaatc tggaccaatg gtagaagaag gtggtcattc aggtggcaag gaagaggtcg
    42541 aggacactaa aaagcctgat gtgattattg gtggtcaggg aagcgttact gagactactg
    42601 aggatactca aaagggtatg agtggcagta ctgagactca gccagaggtt gaggatacta
    42661 agcagccaca atcagatatt atcctaggcg gacaaggcaa tgtgattgac acaactgaaa
    42721 atacccaaga gggcatgggt ggccaatcag gtgatactac agagactgag gataccaagc
    42781 agccacaatc agacattatc ctaggtggac agggcaatgt aattgacacc actgaaaata
    42841 ctcaagaggg tatgagtggt tccaacaatg gtcaaacatt tgaggaggac acacgtccta
    42901 agctggaatt ccattttgat aatgaagtgc ctaacgatga tgacgctcct aaaccagagc
    42961 aaccagaaca gccagagaag ccggagcaac caaggaagcc acagcaggag cagcaaagcc
    43021 taccacgtcc aatagagggc aaccagtcat tgccaaaaac acatgaggca aaaggtgtac
    43081 tggctctagt aggagtagga atccttgcta tgctaggact aggcttttgg tttagacctt
    43141 atcaaaaaga ctaaatcaag gctcagcagc tatttaagct aaacagctgt gctcagctaa
    43201 atgataaaac aattaagatt ggagaatgtg gctattagta gcttctccaa tcttttttga
    43261 tagcagcatg tgctttttct gccgtatttt attgagaata atagttgacc agtctaggcg
    43321 attttgctag aatagagagg tcgcaagaca gactaacttt ttcttggttt taggagtgcc
    43381 aaccctaaaa ctcggattaa gcaaaaaagg agaattatta tggcaatctc aaaagagaaa
    43441 aaaaatgaaa ttattgcaca atatgcacgt cacgaaggtg acacaggctc agttgaggtt
    43501 caggtagctg tccttacttg ggaaatcaac cacttgaaca accacatcaa ggagcacaaa
    43561 aaagaccacg caacttatcg tggattgatg aaaaaaatcg gacaccgtcg taacctatta
    43621 gcatacctac gtcgtacaga tgttaaccgt taccgcgagt taatccaatc acttggactt
    43681 cgtcgttaat tggcttgaca gaggtcattt tagagataac caagttctat tgaaaaaaga
    43741 tctgctagtg tactgacccc caaaagttgg acacgacata ttagtgaaag gatttagttc
    43801 tgtattgcac agggctaagt ccttttagct ttgctttaat gcgtttgttg ttgtagtaaa
    43861 aaatgtaatc tgtaatagct tgttcaagct cattaaggga ttgataagtt gtctcaaggc
    43921 cgtaaaacat ctcagatttg aaaataccaa agaaggactc catcatccca ttatctggac
    43981 tatttccctt gcgagacatg gatggacgaa tgcctttagt ctccaaaaag tgatgataag
    44041 actgatgttg atattgcca
//
LOCUS       DARYLJ010000012        42296 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYLJ010000012 DARYLJ010000000
VERSION     DARYLJ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42296
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..313)
                     /locus_tag="TU746_000601"
     CDS             complement(<1..313)
                     /locus_tag="TU746_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0890973.1"
                     /translation="MDVKIQDIRKSYKDRDILKGVSFEIQKGTICGLLGINGAGKSTL
                     MKIIFGLEKADSGNVIFYNQKDQHVNYEIGALIESPAIYMNLSAFDNLKTRALLYNIS
                     GE"
     gene            complement(797..2149)
                     /locus_tag="TU746_000602"
     CDS             complement(797..2149)
                     /locus_tag="TU746_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0890974.1"
                     /translation="MTKTYSIRYRVGITVGEILIGIAILVISLLIIPYLLVFTKQLNI
                     HGTSFDIVLGDKVSTEEITKQMDTLTFDYVLFNRKNGEVLNGNYQKTELSYYETVFED
                     KKPINVGTIDYKAYSNDQILLVVRQPTLPEFVNPSLRKVSFNTLSIILFIVGTLSIVF
                     ISVTKLLREFAHDFRLIQKISLNMGSRDYKIERSTTKISEFNDILAMLYQKDDELTIL
                     LEAERAEKKDLSFQVAALSHDIRTPLTVLKGNLELLEMTDLSNQQISFIGSINHSVSV
                     FEKYFNSMITYSRLLIEERDYQEVIEVTEFMSGLQIEIQEIMHTEQVDFDMKNNLRIT
                     HFKGNRFNLERALINILVNAAQHATDVKQVSLTAKEEQDQLIFEIWNSGSKFSKQALN
                     GANKLFFTEDNGRSSKHYGIGLSFAQGVAVRHQGKLQLLNPLKGAQVNLIIRKYELLL
                     "
     gene            complement(2142..2825)
                     /locus_tag="TU746_000603"
     CDS             complement(2142..2825)
                     /locus_tag="TU746_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0890975.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGLNLGGDDYLPKP
                     FSVNQLIAKVSAHLKREERVKHGENVEKITRELLPITFYLQEKMLCVSGKPVPLTSRE
                     YHILELLSSHPNKVFTREDIYEHVYDDEANALFRSISEYVYQIRIKFAPFNLNPIKTV
                     RGVGYKWYD"
     gene            complement(2862..4238)
                     /locus_tag="TU746_000604"
     CDS             complement(2862..4238)
                     /locus_tag="TU746_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL0890976.1"
                     /translation="MLTMKHKMLIFCLLLSIFVSQFHMLHVYAETSSKTQYNILIKES
                     LDTNKVKKQLNDQGMIVLDEIPEINVLTIAAANDSSMILEKNCNYIDDISRNNTFTVN
                     PKMTYQFGHAFYLDSDLNYWNKQWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNT
                     DISSKIISVQNFTEDPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMY
                     KVFEEGNAQDEWILKAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAI
                     NYAHKQGSVVVASVGDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVT
                     VGSVDGDGAISNFSNRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLE
                     GKYTYGYGTSIAAPKVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLL
                     NITDFISK"
     gene            complement(4406..4537)
                     /locus_tag="TU746_000605"
     CDS             complement(4406..4537)
                     /locus_tag="TU746_000605"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890977.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(5646..7592)
                     /gene="thrS"
                     /locus_tag="TU746_000606"
     CDS             complement(5646..7592)
                     /gene="thrS"
                     /locus_tag="TU746_000606"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL0890978.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(8183..9517)
                     /locus_tag="TU746_000607"
     CDS             complement(8183..9517)
                     /locus_tag="TU746_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL0890979.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(9519..10517)
                     /locus_tag="TU746_000608"
     CDS             complement(9519..10517)
                     /locus_tag="TU746_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0890980.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(10813..12288)
                     /locus_tag="TU746_000609"
     CDS             complement(10813..12288)
                     /locus_tag="TU746_000609"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL0890981.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(12358..13359)
                     /gene="ccpA"
                     /locus_tag="TU746_000610"
     CDS             complement(12358..13359)
                     /gene="ccpA"
                     /locus_tag="TU746_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL0890982.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            13533..14618
                     /locus_tag="TU746_000611"
     CDS             13533..14618
                     /locus_tag="TU746_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL0890983.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSVLPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(14792..16375)
                     /locus_tag="TU746_000612"
     CDS             complement(14792..16375)
                     /locus_tag="TU746_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0890984.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            16613..17464
                     /locus_tag="TU746_000613"
     CDS             16613..17464
                     /locus_tag="TU746_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0890985.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            17725..18393
                     /locus_tag="TU746_000614"
     CDS             17725..18393
                     /locus_tag="TU746_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL0890986.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            18508..19434
                     /locus_tag="TU746_000615"
     CDS             18508..19434
                     /locus_tag="TU746_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0890987.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(19418..19606)
                     /locus_tag="TU746_000616"
     CDS             complement(19418..19606)
                     /locus_tag="TU746_000616"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0890988.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(19718..20185)
                     /gene="smpB"
                     /locus_tag="TU746_000617"
     CDS             complement(19718..20185)
                     /gene="smpB"
                     /locus_tag="TU746_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL0890989.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(20188..22512)
                     /gene="rnr"
                     /locus_tag="TU746_000618"
     CDS             complement(20188..22512)
                     /gene="rnr"
                     /locus_tag="TU746_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL0890990.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(22599..22835)
                     /gene="secG"
                     /locus_tag="TU746_000619"
     CDS             complement(22599..22835)
                     /gene="secG"
                     /locus_tag="TU746_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL0890991.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(22881..23027)
                     /gene="rpmG"
                     /locus_tag="TU746_000620"
     CDS             complement(22881..23027)
                     /gene="rpmG"
                     /locus_tag="TU746_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0890992.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            23515..25401
                     /locus_tag="TU746_000621"
     CDS             23515..25401
                     /locus_tag="TU746_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0890993.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQG
                     ERGEQGPQGERGEQGPRGENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQ
                     PEVKPQPETKPQQPNKPSTITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKR
                     KRKQ"
     gene            25713..26753
                     /locus_tag="TU746_000622"
                     /pseudo
     CDS             25713..26753
                     /locus_tag="TU746_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
     gene            complement(26916..27509)
                     /locus_tag="TU746_000623"
     CDS             complement(26916..27509)
                     /locus_tag="TU746_000623"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL0890994.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(27506..28327)
                     /gene="mutM"
                     /locus_tag="TU746_000624"
     CDS             complement(27506..28327)
                     /gene="mutM"
                     /locus_tag="TU746_000624"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL0890995.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            complement(28742..30541)
                     /locus_tag="TU746_000625"
     CDS             complement(28742..30541)
                     /locus_tag="TU746_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0890996.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            complement(30702..35342)
                     /locus_tag="TU746_000626"
     CDS             complement(30702..35342)
                     /locus_tag="TU746_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL0890997.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            complement(35515..36862)
                     /locus_tag="TU746_000627"
                     /pseudo
     CDS             complement(35515..36862)
                     /locus_tag="TU746_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(36927..38243)
                     /locus_tag="TU746_000628"
     CDS             complement(36927..38243)
                     /locus_tag="TU746_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0890998.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            complement(38236..38568)
                     /locus_tag="TU746_000629"
     CDS             complement(38236..38568)
                     /locus_tag="TU746_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0890999.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            complement(38578..38895)
                     /locus_tag="TU746_000630"
     CDS             complement(38578..38895)
                     /locus_tag="TU746_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0891000.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            complement(38919..39818)
                     /locus_tag="TU746_000631"
     CDS             complement(38919..39818)
                     /locus_tag="TU746_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL0891001.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            39998..41200
                     /locus_tag="TU746_000632"
     CDS             39998..41200
                     /locus_tag="TU746_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL0891002.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            complement(41363..41839)
                     /locus_tag="TU746_000633"
     CDS             complement(41363..41839)
                     /locus_tag="TU746_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0891003.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(41984..42193)
                     /locus_tag="TU746_000634"
     CDS             complement(41984..42193)
                     /locus_tag="TU746_000634"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891004.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
BASE COUNT        12893 a         9929 c         7708 g        11766 t
ORIGIN      
        1 tttcaccaga aatgttatat aagagtgctc tggtttttaa gttatcaaaa gctgacaaat
       61 tcatatatat cgctggagat tcaattaatg caccgatctc atagttcaca tgctgatcct
      121 tttggttata aaaaatcaca tttccactat ccgctttttc taaaccgaaa ataattttca
      181 ttagcgttga tttcccagca ccgttgatac caagcagtcc acatatagtg cctttctgta
      241 tctcaaatga aactcctttt aaaatgtctc tatctttata agatttccta atatcctgaa
      301 tttttacatc catgattaca cctccttttt tatttaatca tacggtttct ttttcaatat
      361 ttgttcagaa aataatgaaa gcatcaagat ttggaataaa aagaaaatca aacattttta
      421 tagaagcaag caaccaaatg ttcttacaac gtgaatatgg aacctatctt tgtccggtta
      481 aagacttatt tgggctacaa acgttgcata accttcatta tgactaaaag ctataatgtc
      541 agtaaaataa tattcagttg attcttgagt atttaagaat atgaaggcca gcgagttcag
      601 aatatgaaaa aagcccgttg aacgggcgat aatcaagtaa acactgttca gtgattgtct
      661 ttaggctcgg ctgaggagat caacctacag aagccaaggc acttgttttt gaagcaatct
      721 ccaaaaagtt agacagaaac tctaacgaat ggaagtacag ctcatctaac gggtggtcat
      781 gatttaacta tctactttac aggaggagct catactttct aatgattaaa ttaacctggg
      841 cacccttgag tggatttaat aattgtaact taccctgatg ccttacagcg acaccttgag
      901 caaaagataa accaatccca taatgcttgc tgcttctacc attatcctca gtaaagaata
      961 atttattagc accatttaat gcttgttttg aaaacttcga accactattc cagatttcaa
     1021 aaattagctg atcttgttct tcttttgcag ttaagctaac ttgcttcaca tcagtagcat
     1081 gctgtgcagc attaactaaa atattaatga gagctctttc taaattgaat cgattacctt
     1141 taaaatgagt gattctaaga ttgttcttca tgtcaaaatc aacctgttca gtatgcataa
     1201 tttcctgaat ttcaatctgc aaaccgctca taaattctgt tacctctata acttcctgat
     1261 aatctctctc ttctattaac aagcgagaat aggttatcat tgaattaaaa tatttctcga
     1321 atactgaaac actatgatta atagaaccaa taaagcttat ctgttgatta gaaagatctg
     1381 tcatttcaag taattctaaa tttcctttta aaaccgttaa aggtgtcctt atatcgtgtg
     1441 aaagagccgc tacttgaaaa gagagatcct tcttttcagc tctttcagct tctaacaata
     1501 tcgtcagttc atcatccttt tgatagagca tagctaatat atcattaaat tcacttattt
     1561 ttgttgttga gcgttcaatt ttataatcac gactccccat atttaaagaa attttttgaa
     1621 ttaaacggaa atcatgagca aactctctca atagctttgt gacagagata aatacaatag
     1681 atagtgtccc tacgataaac aggataatag ataaggtatt aaaggaaact tttcgaaggg
     1741 agggattaac aaactctggg agtgttggtt gtctcacaac caataatatt tggtcattac
     1801 tataagcttt atagtcaatt gtacccacat taattggctt tttatcctca aaaactgtct
     1861 cgtaataact taattccgtt ttttgatagt tcccattaag aacttcacca ttctttcgat
     1921 taaaaaggac gtaatcaaac gtaagtgtat ccatctgttt agtgatttct tctgttgaaa
     1981 ccttatcacc taaaacgata tcaaaacttg tcccatgaat atttaactgt ttagtaaaca
     2041 ctaacaaata gggaatgata agaagagata taactaaaat tgctatccct attaaaatct
     2101 cgccaactgt tattcctact ctatacctta ttgagtatgt tttagtcata ccacttatac
     2161 cccactccac gaactgtctt aataggattc aagttaaaag gagcaaattt tatacgaatc
     2221 tgataaacat actctgaaat agagcgaaat agagcatttg cttcatcatc atagacatgc
     2281 tcatagatat cttcacgagt gaataccttg ttaggatgac ttgaaagcaa ctctaaaata
     2341 tgatactctc gactcgttaa tggtactggt tttccactaa cacaaagcat tttttcttgt
     2401 aaataaaagg tgattggtaa taattctctt gttatctttt cgacattttc cccatgcttt
     2461 actcgctctt cacgtttcag atgagcactc accttagcta taagctgatt cacactaaaa
     2521 ggcttcggga ggtaatcatc tccaccaagg tttaatcctt taataatatc gtcttcagta
     2581 tctttagcac taacaaagat aataggagaa gcaactttat ctcggattaa ttgacaaatt
     2641 tgtgtacctt caacattagg catcatgaca tctaataaaa tcaagtcaaa cccttgaaaa
     2701 tctctaaaat tgattggaaa agtcacttct tgataggttg ttaccttgta atttttcatc
     2761 tcaagaatgg tccgcataag ttttaaaatc tcataatcat catcaacaac tagaatctta
     2821 tacatagtct tacctcataa tagttacact gttattttac actattttga gataaaatct
     2881 gtaatattta acaatctaat tggttttcca ttatcatcca agctactcca agagttacta
     2941 tacaaaatag ttatggcctc atctggttta tcttttaaat catatttttc gatgattaaa
     3001 cctaaggcag cagctacttt aggggctgca atagaggtcc cgtagccata agtatatttc
     3061 ccttctagtg ttgggataat aacccaatct tgctcaaata atttattgtt aatccaagtg
     3121 tcatagccat gaagcgctag cttcttgctt cctccacctg ccgcaaagat atcaacgaca
     3181 ttccttccac gattggaaaa gttagatatt gcaccatcac catcaacaga tcctactgtc
     3241 acaacattat ctagctgtgc gggaatatcc tctattgtcc catcgactga actaaacgct
     3301 cttcctgtga gagcactgac taagttctta agctcagctt gattatttaa gttagctccc
     3361 tcatcaccaa cagaagcaac taccactgag ccttgtttgt gtgcataatt gattgcccgt
     3421 tgatagctat tgattagagc agttctatct tcatcaatat ttgatgaagc ctttaataaa
     3481 tactgaccaa gactcaaatt tatgacatca acatcatcct ttgctgcttg aataattgct
     3541 tttaaaatcc attcatcttg agcgtttccc tcttcaaaca ccttatacat tctaaccttc
     3601 atgcctggag caattcctgt ataataacca tttgaagaca tttgtccaac aacagatgta
     3661 ccatgacctg ttttatccaa aacattatta acatcaattg ccttagttac tggatcctcc
     3721 gtaaaatttt gaacagaaat gatctttgaa gaaatgtcag tattattatc agtaatacca
     3781 gaatctatta caccaatggt tacctcacct gatgacttat gccaaaacct actactagta
     3841 ctaatacttc tttgcatatc ccattgttta ttccagtaat ttaaatcact atctaaataa
     3901 aatgcatgcc caaactgata tgtcattttg ggatttactg taaaagtatt attccttgaa
     3961 atgtcatcaa tatagttaca attcttttcc aaaatcatag atgagtcatt tgcagcagcg
     4021 attgtcaaaa cattaatttc aggaatttca tcaagcacta tcattccctg atcatttaat
     4081 tgctttttta ccttattggt atctaagctt tcttttataa gaatattata ttgagttttg
     4141 ctactagtct cagcatagac atgtaacata tgaaattgag atacaaaaat agacagtagc
     4201 aaacagaaaa tcaacatttt atgcttcatg gtcagcactc ctttaagtat tgtttttaca
     4261 cttatcgtat gactaacatt tcagatttgt ttcagattct agaaaataat acttactatt
     4321 gtgcttattt aagtccaaaa attagcatta cactcattaa gtatctgaga ttaatctagc
     4381 taacattcta aattgttttc tcccactaat cttttgttct taattccgac ttataattaa
     4441 agacaaaagc taatttttct aactgcctcg catagcactc atacttgcca atcattgttg
     4501 tcatcgtctc ctgattgagc ttagtttctt cttccacctg ctccagttta ctagctgata
     4561 tgcaagtgca atggtcgttt tttgtgaatc acacctactt tgaatctggt aaaatcattc
     4621 tactaacaaa cttcctgtgt aatttctagt agcctaggta gcctgataaa gagatttctt
     4681 caaataaaaa taaccatgtc gaatgccagc gctccatttc ttaccagcat tttcattatt
     4741 ccccagctaa agctctatcc atgaggctaa gtgacctgtg cttagaatta actcatatcc
     4801 acactagtct cagaaataaa gactgaagct atcatgatgt cactactagg aatgaatgaa
     4861 atctagggtt tctacttgac agtcatagtg agacaaacaa gcggcaattt gctcttctaa
     4921 actcccgatt tgtttctaat agcaagcata aatctccata gactaccccc atagaaaatg
     4981 gtggtgattg gagaaatcac cattaagtgc ttcacgacgt tgaggagctt tcttcttcaa
     5041 actagtataa acaattaatg gactacttac tctagctgtc ataggcgttt gagcaatcag
     5101 tagttgaaat agcttgcaac cgaaagcacc cagcatactc tcaatgcgga tcggaagttc
     5161 aatgccacct aactgtagaa ttttataatg caaattgtcc tttattaaga accttattga
     5221 tcattttaag ctttagttcg ggagaggaac gaatcttttt ccttagcagc tttacaatca
     5281 attaatcgtg ctaaatactt taaatggaat tgattgatat caaattgttt gaatgaataa
     5341 ctctggtttt gtaggccgca gatttctacc ttgtcttgat gtcttaatgt catgttaaaa
     5401 gcaccccatt cgttagatag tttgtctaac ttttggggcg cagttcattc attagatttt
     5461 ttatctaatt tttgagaagc agtttacttc tgatgagggc ttctatattg ctttcattag
     5521 ttctatgagt gagagcaaag ctcttgtagc tatttgtccc agattttttt atgtcatctg
     5581 ttttgcaagt caagctgacg tctgcttaat cagcctatct aaaaccagct tgcttggtct
     5641 gctttttagc cttcagctgg gcgtgatttg cgggcaatat cagccaaaat gttatcaaca
     5701 aatgctgaaa tagcttcggt atgtgttgcc ttactgccat agcggcgcac attaactgac
     5761 ttgtcctgca tctccttatc accaacgatt aattggtaag ggattttact ggtttgagag
     5821 gcacgaatct tatattgcat tttctcatta cgatcatcca catctgcacg aatcccatga
     5881 tcacgaagga ttttagcaac ctcccaagca tagtcaatat gggcctcatt ggaaattggg
     5941 ataactgtta cctgacgtgg tgccagccat gttgggaaag ctcccttata ggtttcaatc
     6001 aaaatagcag taaagcgctc catggttgaa atcaccccgc ggtggatcat caccggacgg
     6061 tgttcttctc catcagcacc aatatagctc agattaaaac gctcaggcag taagaagtcc
     6121 agctgaatgg ttgatagggt ttcttcattt ccaagggctg ttttgacctg aatatcaagc
     6181 tttggcccgt aaaaggcagc ctctccttct gcttcaaagt aatcagcgcc catttcatca
     6241 agcgcagcct tcagcatgct ttgagcattt tcccacatct catcgttatc gtaatattta
     6301 tgtgtatcct ttggatcacg ataggacaga cggaagcggt aatctgttag gttaaaatcc
     6361 tcataaacgt caataatcag ctgaagagct cgctggaatt cctcctgaat ctgctctggc
     6421 gtcacaaaca ggtgcccatc gtttaaggtc atctcccgca cgcgctgaag ccctgaaaga
     6481 gcccctgatt tttcatagcg gtgcatcata ccaagctctg caatacgaat cggcagctcg
     6541 cgataggaat gcacatggtt tttataaacc tgaatatggt gtgggcaatt cattggacga
     6601 aggacaaatt cttcaccatc tcccatatcc attgtcggga acatatcctc ctgataatgc
     6661 tcccagtggc ctgatgtttt ataaagctca actgaagcaa gcggcggagt ataaacatgc
     6721 tgatagcctg atgccagctc tttatcagtg atatagcgct caagcgtgcg acgaatcgtc
     6781 gctccatttg gtagccaaaa tggcaagcct tgtcctacct cctgagagat cataaacaaa
     6841 tcaagctcct tgcctagctt acggtgatcg cgctccttag cctcctcaag gcgtgtcaaa
     6901 taggccttga ggtccttttt atcaaaccag gctgtcccat agacacgctg catcatgtta
     6961 ttatcgctat tgccacgcca gtaagctcca gctacattta acaaatgaaa gacccgaatc
     7021 cgacctgttg acggcacatg aggaccacga caaaggtcca caaattcacc ctgacggtaa
     7081 acagttaagc cagccgcatc atctgcatgc tcattaatca actcaacctt ataagggtca
     7141 tccttaaaaa gctcaagagc ctcttctttt gtgatctcct cacgaataca tggaaagttc
     7201 tctttgacaa tttttttcat ttcctcttca atgcgaggca ggtcttcgtt agagatttga
     7261 ccatcagcat tatctgtatc ataataaaaa ccatctgcaa tggcagggcc tacaccaaga
     7321 tgcagcttgg ggaacaagcg cttagcagct tgagcaaaca agtgagccgc agaatgacgc
     7381 agcacctcaa aagcgtcctc atgatcagca gttataattt ctatactacc gtcctcttca
     7441 atggcgcgcg tggtatcaat taattgacca ttaaacttac cagccaaggc ctttttagct
     7501 agagatttgc tgatagagtc agcaatctca aaggttgtga caccagattc aaattcacgc
     7561 accgcgccgt ctgggaaagt gattgtaatc atctgttttc tcctataaac catctagata
     7621 cttaaaacaa gctaatcaag cagggctata tctcccaagc cttctgctgc tacgacaaaa
     7681 taaaaactga ctgcctccca aaggacgcaa tcagcgtggt tccaccttta tttatgcatg
     7741 acaaagaaat cctgtcctgc acctcagctt ggctatatcg tgaccaccgt tttatgtttg
     7801 cataaaagca aggaaggagt attacactag acaccctgtg ctcttctcac caaccagcac
     7861 tcgcttaaag gatgcgacct aatctaactt gtcttcctga ttattatagc aatatttgga
     7921 aataattcaa gtgatttttc ctaaaaaagc tgagataagc ccacagacct ccaagcccac
     7981 aaggcaagaa tgactaggca aggaaccctg aaacttctgc cacaagcctt tgaagaacag
     8041 ctcaaacagg acttgccgcc tgtcgtctca gttcacaaga caacaaacta aatcctttag
     8101 acaaatgatt atcctaaaga gctatctgct ctctcacgca gaaccaaagc ctgtaattgc
     8161 aggcttcttt gtttatttag ccttagtcca aaaagtctcg gatcgcattg accagcttga
     8221 taggggcttt gagcaccttg acagatgtca gtgcagttgc cttagctgct cgcttaggca
     8281 agtgaatcgc tccttgaacc agcttgattg agccactctt ttctgttcga ttgagataga
     8341 gacttagctt tttcgtctct ttattgtgtc gcgaaatcaa ggtatctaaa taaaaggtgt
     8401 acactgattt gccaaaatgc tgagctgaaa tctcatagcg cttctcatct agcagcctct
     8461 ggttcatttg aggtgtttct aaaatggcat caataatcgc atctgacaat tctgactcag
     8521 cataataaag tgttccaaac atcttatcgg taatcaaatc atctaggtag ggattgccat
     8581 gagcgatgat gggcttgcca ctagcaaggc tctcaatata agttagcccc tgtgtctcac
     8641 tcgttgacgc tgaaataaag aaatcacagg ccttataata aagcccaacc tgatcatgag
     8701 caatcatacc agtaaagacc acatgatcct caacgcctaa gctgacagcc agctccttta
     8761 aggcttgaag ataaggacca tcaccaacaa tgacaagctt gatcctgcta ttttcactca
     8821 aaacagctgg cagctgatgg ataatagcct gaatattctt ctcataagac acccgcgaca
     8881 ggctcaatag catggtctca tcatcagaaa tggccaattc ctttctcaag gcagcgacat
     8941 cttctttttt aatatcctca cgaacatagt tctctagtgc aatgccagtc ggaatcacac
     9001 gcttaggaat ggttacctcg tacccttcca aaagatttag cacaatccga cttgggcaaa
     9061 taacaccatc aaggtccttt aaatacccac gaagcagggg cttgaccatg ctaggtcgaa
     9121 tgatcttacc attagcaata tagctcacat aatcctcata ctgggtatga taggtgtgaa
     9181 caaccggaat tcttaaggcc ttgcccacca ttttgcccaa caaacctaag ctaaactctg
     9241 tttgagtatg gataatgtct aaatgatatt ccttagcaat cttgtaggag gaaatgagcc
     9301 cacgataaac cacacgacga tccgtaaagg acacaaaagg aacacttggt aaccgaataa
     9361 tggtcggatc ctcaaagcgc ttaacatgct tgtctgttgt tgtgaaaata tagacctcat
     9421 gcccctcttt ttccagctcc tcctttaggg tgcgaatact ggtagccact ccggaaacct
     9481 gtggaaaata ggtatctgta aatagaccta cacgcatctt ataactccat tactttttga
     9541 taaatagcca ctaattgatg agcaatccta tcaaggctgc gcccctcggc gacacgatag
     9601 ccggcctctg ttttgttgct ttcccctgaa agaatgcgtc ttaaggctgc aacaaagcct
     9661 gaggtatcat ttgccaactc agcactgtct tgatcaatcc agccctcata gactggtata
     9721 tcgcgtaaaa caagatgctg ccggctggct aaggcttcga gaaccacaat gccttctgtt
     9781 tcctcacgac ttgggaagaa aaaggcgtca gccccagtca tagccccctc atacacatct
     9841 cccttgatat aaccagggaa gatcacatta tcggggtgct taccgttgac aatctggcgg
     9901 acacgagcag gaataaccca tttattggta tcaccaaacc agataaaccg aacatctggc
     9961 atcatctcag caaccttaac aaactcatca atcccttttc taagaaagaa aagccccgct
    10021 cccatgacta ccttctcacc ctctttgagg ttaaaataac gccgaaaggc agcttctttg
    10081 tcagcattag caccatattg ctccaaatca atcccattag atactgcaaa aataggagtc
    10141 ttaaccccgt aatgctcaat caaggcttta gaataagggg tcggtgtgat aatggcgtcc
    10201 gccttattgt aaaagcggca gagataggct ttgaataaag gagacactag atttgaaaaa
    10261 ataaaggaat ttctaaaatc ctcctctgtc gaatgcccat gcatgatcac ctttttaccg
    10321 gccttttgag cctttgacat caaaagccag cttttaagcc cataggtatt gagatgaacc
    10381 aaatcatagt cgtcctttgg atcagtggtg aactcctgtc ccacaagcga tagcgctttt
    10441 gcctgatgct taatcgctcg cccgatacct gattttctta aataattttc tgcttctaaa
    10501 tacaataaga ctttcatact gtctattata gcctatttta tggtattttt cactaagaga
    10561 gttaaaaatc agcccttaga ctgattttag ggtaaggctt cttctacccc tatactcatc
    10621 tcaaaaatgc ttttaagtcc tgcttttgct gtcatcaaat ggctgatctt ggtaatatca
    10681 gctagaccaa gatcgtgaaa gctccagctc aaggctcacg tattagccct ttcaagaaag
    10741 cctcccacct ttctcactgg ccaaaaagcc agcaagacct ggccttttct tctgattaat
    10801 tcagcctatc agctaagctt cttcttttgg ctgtgctttt tgtaacaccc aggctgagat
    10861 agagcctgcc tctaccttga aatctgccca gccatcctca gcaacaacaa cagtctcctg
    10921 acaattgtct aagaaatcac aaaaaacttg accagcatag gcttgaccaa cctccatgtg
    10981 cttccagcct gcatcgccat tagacaaaac aactgccaaa ggctgaggac gctgatcatc
    11041 tcctaagcag gtccagccga tacaattggc atgatcaaag taatcaatct gctccccata
    11101 gaccagctgc tgcctgagct ctgccatttt tgtgataacc tccttaaaac tttgctgagg
    11161 gtagtctcca gaaataccat aataatcacc ataaaaaaga cagggcttgc cctcttgtcg
    11221 taaaagaatc aggccatagg ctaagggctt gaaccattcc tcaacagttg actctaaggc
    11281 ttgccctctt tgggtgtcat ggttttccac aaaggtaata gcaaggtctg gccgactagc
    11341 cacaagactg ccatcaaaaa tagtggtcaa atcaaaatca gctccctgct ggctagcatt
    11401 aaaaaaggac atgtgcagcg caacatcaac tagagcaaac tgagccttcg ttgcttcgag
    11461 gtaatcctcc atagattcct gatcagactt ccagtattct ccaaaaacct ctaaatcggg
    11521 ctttagctgg gtacgaatat cattgataaa ggtctgaata aaataagaat caatatgctt
    11581 cacagcgtct aaacgaaagc cctcaatacc agttgtctca ataaaccact tggcccaatc
    11641 ctgtaaattt tggattacct caggatgctt gaaatctaag tcattgtaca ttagataatc
    11701 aaaattacca tgctcatcgt caatcagctc atcattggcc cagcccttgt tatcaccggt
    11761 gatcatgtaa atacctgttt cattagcctt ggcgtcataa tccaatcccg taaaatggta
    11821 ccagtgccat ttaaagtcat tataggtatt ttgtctgccg ggaaaatcaa agcctgtcca
    11881 gccttcaatc tcatagggct ctgtaagggc ctgctgacgg ttctctggat tcattttgat
    11941 cacagaaaag cgttccttgt gatcaccatt agccttgtgg ttcagcacaa catcagcaat
    12001 aggctttatt tttgcctctt ttagggctgc aatcagctgc aaataatcct ctttgctgcc
    12061 atattttgtg ctgacagttc cattttggtt aaactctccc aaatcaaaca aatcgtaaac
    12121 accgtacccc acatcatcag agctagtgcc cttaaaggca ggcggcagcc acagctgact
    12181 aacccctagc tgttgtagct caggaatact gcttttcagc ctttgccaat gccttccatc
    12241 ggcaggcaaa taccattcaa aggcctgcat taatagttga tgactcatct taacctccta
    12301 aaaaggacaa accagaaaac tcctagtttg tcctcaaaac tgcctaaaca ggcagaacta
    12361 ttttgttgtc ccacgctttt taatgccatg gttcaataaa atttcttttt cttctaattc
    12421 ttccttattc atgatcttag tgagcatacg catgctaaca gcccccaagt catagaccgg
    12481 ctggctgata gagctcaaat ttggacgtgt gtactgaacg actggagaat cattgcttgt
    12541 gataatctca aagtcttctg gaacacgctt accagcttca aaaagaccat tcaaaaggcc
    12601 tgctgccagc tcgtcctctg caacataggc agctgtcgct ccggaattga tcacacgctg
    12661 agccagctca aagccttcct tataagaata gttggcctca aacaccagac cctctttaaa
    12721 gtcaagcttg ttcttcttga gtccgtcctt gtagccagct aaacgcacct ttccgttgat
    12781 atcatcaatg agcggccctg aaacaaaggc aatgctttgg tggtctttag ctaaaatatc
    12841 caccacatca gcaacagccg ccttataatc aatgttaaca cttggcagct gatgatccag
    12901 atcaaccgtt cctgccagaa cgattggcgt acgcgaacga gaaaactctg cccgaatctt
    12961 gtcagtcaag tgatgtccca tgaaaataat gccatcgacc tgctttgcaa agagggtatt
    13021 cacaacattg acctctttat catcgtcctc atcacttgaa gcaagaacaa tattgtactt
    13081 gtacatagca gcaatatcat caattccctt tgccagaata gaaaaatagc tatttgcaat
    13141 attaggaatc acaacaccga ctgttgttgt ctttttactt gcaagaccac gagcaacagc
    13201 atttggacga taatcgagac gatcaataac ctctaagacc tttttgcggg tattttcctt
    13261 tacatttttg ttaccattta caactcgact aactgtcgcc attgaaactc ccgcttcgcg
    13321 agcaacatca taaatcgtga ttgtatcatc tgtattcatt cttcatcttc ctttctaact
    13381 gaaaatgacg ctttcaaaaa gtattttagc atgatttgta accactttca agtattaacg
    13441 gttgattttt gaaaaagttt tcaaaaattc ataataagct tgctttttta agtatttttt
    13501 ggaaaaatag aaggcagaaa gaaggtttat ctatgactaa attagatcaa attcgtttgt
    13561 accttaatca ggaaaaggct gagcttgcta tcttttctga ttctgtaacg atcaattact
    13621 taactggttt tttatgtgat cctcatgaaa ggcagatgtt cctatttgtc tatcatgaca
    13681 aggctcctgt tttgtttgta ccagctttag aggttgcaag ggctgaacaa ttgctggact
    13741 tccctgtttt tggctacgtt gactctgaaa atccttggga aaaaatcaag tctgtcctac
    13801 caagcacagc agcaaagacc atttacgctg agtttgatca tttgaacatt accaagtttc
    13861 aagggctgca gagtgtcttt tcaggacgct ttgacaatct aaccccttac attcaaagaa
    13921 tgcggctcat caagtctgct gacgaaattc aaaaaatgct gattgctgga gaatttgccg
    13981 ataaggctgt caatgtgggc tttgataata tttcacttga cgtcaccgag acagatatca
    14041 tcgctcaaat cgaatttgaa atgaaaaaac aaggcatcag caagatgagc tttgaaacga
    14101 tggttttaac tggtaacaac gctgcaaacc cacatggcat tccaggaacc aataaaatcg
    14161 aaaacaatgc cctgctgctc tttgaccttg gtgttgaaac attaggctat actagcgaca
    14221 tgacgcgtac agttgccgtt ggaaagccag accaatttaa gcttgatatt tatcagcttt
    14281 gcttagaggc tcagctaact gctcttgata tgattaagcc aggagtgact gcagctcagg
    14341 tagatgccgc tgctcgccaa gtgattgaaa aggctggcta tggcgactac ttcaatcaca
    14401 ggctcggcca tggtatcggt atggacgttc acgaatttcc atcaatcatg gctggcaatg
    14461 acctgattct tgaagaaggc atgtgcttct cagttgagcc tggtatctat atcccaggca
    14521 aggttggggt tcgtattgag gactgtggtc acgtaactaa agacggcttt gagctcttca
    14581 cccaaacacc aaaagaatta ctatactttg aagggtaata ggaggcttaa aaagcctgaa
    14641 acaaaatgtc tcagacccta atatctaaag caacagcact tggtctgtta cttttcatat
    14701 tacaggctat tttctcacaa ggaaaagtca aagcacccct tgatgggaaa tcagaggggc
    14761 aaaagctatt tgtactaagc tcaaaagcta atcaagagca cctgaccagc tctttatcct
    14821 ttaagtgata aatgcaatca taagactgtg cattatattt atgagctatc tcaaccatgg
    14881 tgcaggggag tgaatggagt aactcacgaa tctctctggc gctttctttg tctagggcag
    14941 ctgtgacctc atcagccagc aaaatcggtt ttagtatcag caagcagcgt gcaatttcca
    15001 gcttcatgat ttgcccgcca gagagatttt gcccatctag atggagatca agatctccgt
    15061 ttagctcatt ccaaagatga acctgctgta atatctcctt tagtcgctgg tccgaataat
    15121 cctgaaacag cgtgagatta tctcgcaagc ttccttcaaa tatgtaaggc ttttgatgta
    15181 tcaaagacac aacatcatag gaaggaaaat agcgttttcc attggcagct tcaaaataaa
    15241 tagttccaga ataatcctta tcctcaccac acaaaagagc aaataaagta gatttcccac
    15301 taccactggc tcctgttagc aaggttttgt gccctgctga aatatgacca tctatccctt
    15361 gaaaaataag cctatgatca aaatacttat ctaacctctt aaagtagata tcaagtgtaa
    15421 gatcatctgt aggggttaag gcttgatgtt ttgtctcttc ctccagagcc aatactctaa
    15481 ccatcttctc cttaacagca gttgcagact gtaaactcga agtagcttct aataattgct
    15541 gcaagggaga gacaagattc gtagaagctg ttatcatagc aatgagagtt gttagtgata
    15601 gacttgaata gctcatcacc aacagaccaa taataagagg actaaccaag ccaatccctt
    15661 ttaatggacc agtccaaaac attaccagat tgtgggtagt ataatagcta tattgcttgt
    15721 cttccatatg ctgaatcatt tctaacacat ggtgagcaaa agcttcgttg gcttgattac
    15781 tctgtatcgt gtctgccccc ttagtaaaat cggtgatact ggctaggctt ttctccctcg
    15841 cctgactaag ctctaagcct cgtgattgaa gtaagtgatt gaacacaaac tgtggaataa
    15901 tcatcaaaaa gccaccaata gtaaaggcaa taccaatata aatatcctgc aaaagaaggt
    15961 acaagacaga ggctaagata gataggccaa aaacaggata aatgaataag gggaccaaat
    16021 actcctgcca aaacatagga atatcttggg tcaaaaacga atttaaggct gaagtaaaat
    16081 agttgagctg tttatgataa aaatgatata aagccttctt tgcaataagg caattaaacg
    16141 ctctaaccat agaacgtgct aaaatgttat taagatacat gcacatataa ataaagacaa
    16201 aaaaagctac gcctccaaga ccaaaaagca ataccattcc tttattgttc atatcaattt
    16261 gccctgctat ctgaattaat actgataaca atagtccctg caaggaatag agcaaagcca
    16321 ataaactata caagcaaagc tgccattttg aaatgacttg taaaatactt ttcatatcaa
    16381 tcactcctca cctgaaacct aaatgtatcg ctctcttgga aagtataaac gaaacatcct
    16441 catacaccaa tcatttccac cacaaactag attcttgaat gttaaatcaa gctcttgatc
    16501 aaaatcatgt tctctgattt cttgaacaac cattggttct ctcctttcat tcttactatt
    16561 tctagtatat aatgggaaaa aatacgaaag gaaaaatttc ggaaatccgg atatgaatat
    16621 cagagagaaa tttaaagcaa ttcgtaaaca aagaagacta tccttaaaaa cgcttggtaa
    16681 aatagctggc tcagccacta gtatttctga cttcgaaaat ggaaaaacga acctttctaa
    16741 tgatgtttta ttgcagcttt taggctttat gattgttgaa ataaacgagc tattcgaatg
    16801 ggaggatttt cacgaaaagg aattggttga agccatcaag caaatcgaac tggcaataaa
    16861 atctaaacat attcctgctc tatctcagct acagcaggac tttcaaagct tatctaagac
    16921 aaaggaacag tacatttacc acatcatctc actgatccta accatcacca ttgcagaata
    16981 tcaaaacaaa gagatcgatc cacacatcat gtctgagcta acagactact tctttttctt
    17041 ggagtattgg actaaccttg atgtcggcct actaggaaac atcgtccact acatgacaac
    17101 agatgcccta atcttattga caaatgacat cttagagcat acgcctcaag tactccgaaa
    17161 taacctagat cgtattagga tcgatactgt attaaactgt cttactgtct tgattaatcg
    17221 taaagaggag aaggcaagca gaacacttct taaattatta tttaacaaac attatcctaa
    17281 ttactttgcc tttgaaaagc tctatttaca tgaattacaa gcagtctatg attttaactg
    17341 gaaagataaa gaacaggcgc ttgcagctca tcacgtcata ctggctacca tttcattact
    17401 atttacagct gatgaagcca aagaatggga cagcttcttt caagaaagta ctagctcttt
    17461 gtaatactcc agctcataca ctaaagaaaa gcaaggataa tcacataaaa actaatcaca
    17521 tcactttgcc ctgctagctg aattagcttg ggtcatctct tatgcccagc aaaacatcat
    17581 ctagtctcag ctttcttcca aagcttcttg tctctctggg cttgcaagct tttgatagct
    17641 taagaggcac aagcattaac aaaggctaac aaatgcctgt aaaaatatgc tatgataggg
    17701 gtaacaaaaa cctaggaggt gcttatgtca cacaaatcca ttcatcaaca gcttagaaat
    17761 gctttttcct ttcggacagc ggtacgcgtc tacaatgacc aaaaaatagc caaagaagac
    17821 ttagacctga ttttagatgc tgcctggctc agtccttcct ctatcggcct tgaggcctgg
    17881 cggtttgtcg ttttagaaaa cgaagctgtc aagcatgagc taaaggaggt ctcttgggga
    17941 gcagtttatc agtttgagac agctagtcat atgatccttt taatcagcga aaaaaacgcc
    18001 agatatgatg gcgcttctat caagcaaagc ttattgcgca gaggcattac tgacgagcaa
    18061 gccttggcca gtcgtctggc atgctacgaa gccttccaaa agcatgatat gaaaatagca
    18121 gatgatcctc gggctctctt tgactggact gccaagcaaa cctatatcgc gcttgctaat
    18181 atgatgacca ctgctgcttt tatggggatt gactcttgtc cgattgaggg ctttaactat
    18241 gacaaggtaa atgctatctt agcaaaacat gggattatca accctgatac cgagggtatc
    18301 tctagcatgc tgtctttagg ctatcgcctg cgcgatccca aacactcaca aaccagaaag
    18361 cccagagaag aggttatttc cttctttaac taagcccctt ttgccattgc tcccaaagaa
    18421 agtgcaaaga cagtcctttg ccttttcttt ttcataactg tcgaattatg gtacaatgtg
    18481 tcaaaagacc tatggaaagt gatgcctatg acattattat ctgtaattat cccctgcttc
    18541 aacgaagaag acacgattat tccttatctt gaagaaatga agcaaatcga agcggccatg
    18601 accagccaat tagcctttga atatcttttt attgatgatg gctctacaga tcaaaccctg
    18661 agcgtgctaa gagagcttgc ggggcgcttc tctaatgtgc attacctctc cttttcacga
    18721 cattttggca aggaagctgg actattagcc ggcctagaag aggcaaaagg aagctatatt
    18781 acggtgatgg acgttgacct ccaggaccca cccgagcttc tcccgctgat gtatagcaaa
    18841 ttacaggagg gctttgatgt ggttgccaca agaagacaga gccgacaagg agagcctgct
    18901 atccgttcct tttttgctag actcttctac agattagtca agcatgtctc caacaccgaa
    18961 atcgtcgatg gggtacgtga ttatcgttta atgacaagac aggtggtgga tagtatttta
    19021 gagttgggag aggtcaatcg cttttccaag gggatttttt cttgggttgg ctacaatact
    19081 gcctatatca gctttgacaa tcgtaagcgg cagtacggca aaaccagctg gaactttctt
    19141 gagcttttga actactcgat agacggcttt atcaattttt ctgagatgcc cttaaccatt
    19201 gctacctgga ctgggacact tagctttttg ctatctctgc tagccatttg ctttattgtt
    19261 atacgcaagc tgctttttgg tgatccggtt tcaggctggg caagcactgt atccattatg
    19321 ctatttatcg gtggaattca gctgttttgc atgggaatca ttggaaaata catttccaag
    19381 atcttccttg aaaccaagaa aagacccgtc tacatcatca aagaaaagaa ataacagagc
    19441 aatcatcaag gcccctatca gccgccaatg aggccgataa ggactggttg ccctcatcat
    19501 gacaagcacg acaaaaagac ttgatggtcc caatcaaaac catcaagtct tttttagtat
    19561 gtgaccttgc gtctgcctcg cacctaaaaa gacgagataa tgtcataacc accgtctatc
    19621 tactgacccc aaaaagttgg acaatttagt tttaagcaag ggatttagtt ctgtattgca
    19681 caggactaag caaggccatc agcttgtaaa cagacgctta gcggcggttc acactcttca
    19741 tcacacgccg aatgtcacga tcctgctcgc gtcgcttgat cgattcacgc ttgtcataat
    19801 catgctttcc tttggcaagg ccgattaaca ccttggcaaa gccatcctta agataaacct
    19861 ttagaggaat aagggtcatt cctgtgccct ttagctcatc tgctaggtgc tgaatctcac
    19921 gctttttgag caataatttg cgcgtgcgct ccggatcagc attccagata tttccctgct
    19981 caaagggagc aatatgaaca ttgaccaacc aggcctcacc attcttgatt tgggcaaagc
    20041 cgtccttgag ctggatacgc gcggcacgaa cactcttaat ctccgtaccg gtcaacacaa
    20101 ttccagcctc aactgtctca acgatatgat agtcatgacg agcctttttg tgttgcgcta
    20161 atacattacc ttcacctttt gccatgctta actcctttta cgacctttct ttttagcagc
    20221 tttttggtaa aatggtttct ttgctttttt tcttgtcttc tgctttgatt ttggctttga
    20281 gggcttggac tccttactcc tgctagccct tgaagcagcc ttttgcctgt gcttatgctt
    20341 agctttagct gaccttgtgg tcttttcaac cacatcatag tcactagcca agtaatcaaa
    20401 atcaatgtca cctgtttcct tgtcagccct caccaatcta acccgaatcg gctgacctgc
    20461 tctaaatacc tttcctgagc gttcaccctt taaggagagt gtccgttcat tatagtgata
    20521 atattcaggc aaattggtaa tatgcaccag accttcaatt gtatttggca attcgacaaa
    20581 catgccaaac ttaaccacac tagcaatcac gccatcaaac acatcaccaa tataatctgc
    20641 catgtattct gcttttttca tcgcctcaac cacacgctcc gcgtcaattg cacgacgctc
    20701 tagctgagat gacgatactg ccaattctgg aataacctgt gcaaaatgat ccaccttctc
    20761 ctgcgtgatc tgattgtatt ctcgaatcat gcggtgcacc agtaaatcag ggtaacgacg
    20821 aatcgggctg gtaaaatgcg tgtagtagtc tgctgctaag ccatagtgac catgattatg
    20881 ctcagaatac ctagcctgct gcatagagcg cagcagcatc atattcaaaa cctctgctcc
    20941 aggacttcct tctacctttg ccataaaggc ctgcaaggct tcttgagaaa tcttattagc
    21001 agttccctga atctgaatcc caaaggcact agcgtaatca ataaaggtct gcaatttctc
    21061 tgcctttggc tcctcatgaa cccggtaaat aaatggcaag ccagcccttg aaaaatgctc
    21121 agcaacacat tcatttgccg ctagcataaa ggactcaatc atgcgctctg caacacctcg
    21181 ctggcgcaag accacatcaa ccggcatgcc cttatcattg acaataatcc tagcctcctg
    21241 cgtgtcaaag ttcaaggccc cgcgcttcac acgcatcgcc tctaagatct gatgcagctc
    21301 aaccatagta ctcacatcat cagcaattct atcaaattcc ctaagcgcct cactgtcacc
    21361 tgcaatcatc tgattgaccg cgctgtaggt cattctaaag gttgtgttaa tcactgactg
    21421 acacagctga taatcaacca catgtccctg atgatcaatc tccatgatcg ctgactgggt
    21481 caaccggtca acctttggat tgagagagca gataccattt gacaaccgct ccggcagcat
    21541 tggcaccaca cgatctgtca cgtaaacaga ggtcccgcgc gcagctgcct cacgatccaa
    21601 ggctgaccct tccgtcacat agtaggacac atctgcgata tgaaccccaa gctcaacgtt
    21661 tccattggcc aatctcttga tatggatggc gtcatctagg tctttagcat cagcaccatc
    21721 aatagtgatg gtcgtttctt tgcgcaaatc aacacgcccc ataagatcct gatcactcgg
    21781 agcatctgga atggcattgg cctcagctag aacgtcatct ggaaacgccg atacaatatc
    21841 catagattcc aaaacctcca gcacatcaat gccgacatca tgctgatgcc caataatatc
    21901 acacacagtc cctacaaaat aatcctgccc agccttaggg tattgcacaa tatcagcctt
    21961 aatgatttca gtaccatcta aggcaattgg agattttgcg atataaatcc tctgttgaat
    22021 cctttgattt ttcgacttga tgtagccagc atacttaggg tgatcatcat ctaaaataac
    22081 cctaccaaca accgtcttta aagagcgctc cacgatagct accacgcgag cctctgctgc
    22141 tgtagcctta agccgattag ctggtttttt aataacagcc tcaaccctat cgccatcact
    22201 agcatacccc acatcatcac gaccaataaa aatgtcgtcc tcattgtcat caaccgacaa
    22261 aaagccaaag ccagccttat tggcacgaaa aataccttga acccttatct ctggcttttt
    22321 ttgctgtggt gctctaagaa acacctcacc ctcatctgaa aaagacaaaa gtcccttgcc
    22381 ttccattttg gaaatggctt taatcaggcg aggaaagctc ctcgcatcag tcatctctag
    22441 tgcagccgcc aaatcatgaa tatttgattg gccatgctcc tttaaataat tcgtaatgtt
    22501 ctctatcatc atacctatct tctatttcta acaccatact tgatggttgt gctcattgat
    22561 aaaaaaatga gctagactaa ctctgtcaag ctcactcctt atttacttga taaaatggca
    22621 agcactaacg caattcctaa ccaaaaaaac actagaactg ctgtaaaacg ttgcataaaa
    22681 gcttcaaatc cgcgagcttt tgtacgctca aacaaggctt ctgagccact gctatcaaaa
    22741 acattgctac taggattttt ttgtggctgc ataaagatag caatcacaag caacactgat
    22801 aatactagca atatcgtaag tagtaagtcg tacatgttaa ttcctccact gtagtctcaa
    22861 tcattctaac acaaaaccaa ctaagattca acatgcagcg ttacttttct ctccttagga
    22921 cagtatttag gaaccttaat cttctcaggg tgacttgttt tatttttact agtcaaataa
    22981 tttttgctgc cgcaatggct gcactccaaa tgaatcttta ctctcacatc atttccctaa
    23041 tcttactata ttttatcagc gtcataaggc ttcaaatcac ccgcagcttc tttattaaag
    23101 atatctctag ttattatagc atattatcca gtaagaaaac aaactcagga cttttagcaa
    23161 aaaaggctta agcgccaacc aataaacatt ccaaggctat cggggaatat tttctaatgg
    23221 ttattataaa tcatgaacaa ttacctaaca aagcaactcc aaaacaaaga taaaagacga
    23281 acattcacct tgctgctcag ctatcaagat aaacaatcct gatagcatca attttcttta
    23341 ggtcctcagc aatcggttgt aatatcagac aattcaggtg ttgattaaaa aaaacgaaac
    23401 tacggagacc aattgtcaga aagctattca cagcccgcag gcgtcgtgct aaagtattgt
    23461 ctggaaaaag aaaggtttag gaatgattat acctaaactc aaaggagaga aacaatgaga
    23521 aaaacaatga agaagatgct agcagcctcg acgctctgca tcatcatgtc aggcagcttc
    23581 atcagcggct cagctagagt gttggcggag aagtattatg gttttaatga tggcacagga
    23641 gagcattcac cattccctgt atacgttact ccaattacta aacctaatag gaatactgcc
    23701 aaagttgtct actgtttcaa taaagatatg aagtggccag aaacttggga taaagcagca
    23761 ccaaaaaaac cagataattt acctctatac tacgatatgg aaggtactga tcaattattc
    23821 agtacatatg caagtggaca acttactcct aatgtcagta aagtcttagc taatataatg
    23881 gctaaaggtt atccaaacaa caatgagttt gctcaccatt ttaaactcac tcccaattcc
    23941 gctgtaaaag ttactcaaat cgcagtttgg actgttacgg ataacctaaa aaactattct
    24001 caatacagtc taaccagaga agaggaagct gcattaaatt acctaactga caaaaatggg
    24061 gacgacttta gcgatagtat caagttaaaa ttatacattc cacaaaatcc tcgaactata
    24121 aaatatcaaa atcttctagg ttatgaccta atagttaaaa ctccagaaaa aaaagataat
    24181 tgtaaatgca ccaaaattta tatagaagat aatggaaaag atggctatta tctgtatatt
    24241 tattatgaca acaatgaaaa taatagatat gactcggaca aagatagcct attgcaaaag
    24301 aaatacataa aaaatgggaa agatgggaaa ccaggaagac caggggttcc aggacttcct
    24361 ggccctgctg gacctcaagg gcctagagga gacaaaggag aaaccgggga acgtggacct
    24421 aaaggtgaaa aaggtctaga cggtaagcct ggtgaaaagg gtcctaaagg cgatacagga
    24481 aaagatggta aggacggaca acccggacct cagggaccta agggtgaccc tggacgtgat
    24541 ggaaaagatg gcgaacctgg aaaacctggc gagcgcggtg agaaaggacc tcaaggcgaa
    24601 cgtggacctc aaggacttcc tgggcccaaa ggtgagcctg gaattccagg gcctaaggat
    24661 gaagatggaa aagatggtgc tcctggacat gacggacaac cggggcctaa aggtgaaaaa
    24721 ggggaccctg ggcaacaagg cattccagga cctaaagggg aacctggacg tgatggtaaa
    24781 gatggagaaa aaggcgagcg tggagagcaa ggacctcaag gcgaacgtgg agagcaagga
    24841 cctcaaggcg aacgcggaga gcaaggacct caaggcgaac gtggagagca aggacctcaa
    24901 ggcgaacgtg gagagcaagg acctcaaggc gaacgcgggg agcaaggacc tcaaggcgaa
    24961 cgtggggagc aaggacctca aggcgaacgc ggagagcaag gacctcaagg cgaacgcgga
    25021 gagcaaggac ctcaaggcga acgtggagag caaggacctc aaggcgaacg tggggagcaa
    25081 ggacctcgtg gagaaaatcc tactcctacc ccagatccaa tgccacaacc agaaccacaa
    25141 ccagaaccac aaccaatgcc tgatccagca cctaaaccag aatccaagcc agaacctaag
    25201 ccgatacctc aaccagaggt taagcctcag ccagagacaa aacctcaaca accaaacaag
    25261 ccatcaacca ttactagcca atctagcggc aaatcactgc caaaaacaaa tgacactggc
    25321 agcttgatca cagcatttgg tacaggctta ctcactcttc ttggactagg cttcctagca
    25381 aaacgcaaaa gaaagcaata attaaaacac tacccatagc cttttaatca ttggctatca
    25441 actagataac aaaaagctta tcgttttact cctaacgata ggctttttcg cattccctat
    25501 tgcttggtct caatactatt tttccagctt taggctggtt ttgctaatcc aaaataatat
    25561 cagacaattt ccgttttaat taaaaaaaaa aaaacgaaac tacggacgcc aattgtcaga
    25621 aaatggttca cagcttagag tcaccatgtt aagctattct acgaagaaga aaggtttagg
    25681 aatgactatt tctaaactca aaggagagaa acatgagaaa aacaatgaag aagatgctgg
    25741 cagcctcgac agtctgcatc atcatgtcag gtagctttat cggcggatca gccagaatcc
    25801 tagccgagca gtattatggg tggaatgatg gaacaagagt aaaatcacct tttttccttt
    25861 atgttacgcc aacaaatgaa acgactagga aaaccggaaa aaatggtaca atagtctatt
    25921 gtttcaacag agataaggaa tggccagcaa attgggaaga aggaagatcc ttagaactag
    25981 tgaatgctga aacagcttat aaattaccca tctataataa attactaggt acaactgatt
    26041 cctttactaa aaatgctagt aaaccaagag tatctggaga tattggtaaa gcgctaatag
    26101 ctgtactgaa aaatggttat cctaataaaa atttatccgg attagatgac actaaaagtc
    26161 gaatactaac tcaactagct atctggtatt tcagtgatag ttataataaa gattatttta
    26221 aacaaaatta tgaattaact gatcaagaaa ataactctct tatggagctg attaaagtcg
    26281 gtgaggaagc agctcaaaaa caagaaaaac cagaatatca tttagatata tatataacta
    26341 cagaaaaaaa ttattaacat aaaccttatc aaaacctgct tggttctact ctaattccta
    26401 aacttgaccc taagcctgaa ccagaaccag atcctaagcc taagccagat cctgaaccaa
    26461 tgcctaaacc agagcctaag cctgaaccag agcctaaacc tgaacctaag cctgaaccaa
    26521 tgcctgatcc ggcacctaaa ccagagccta agcctgaacc aatgcctaaa ccagagccta
    26581 agccagagac aaaacctcaa aaaccaacca agccgtcaaa cgctactagc caatctagtg
    26641 gcaaagcact accaaaaaca aatgacactg gcagcttgat gactgcactt ggtacaggct
    26701 tactctctct tcttggacta ggcttcctgg caaaacgcaa aagaaagcaa taagctgaat
    26761 aagctaatgc aagacagcac tagtatataa tgcgtgcatg gtccatctaa tgcagcacaa
    26821 aagccttatc gcaccacgaa tgggtacgat aaggcttttt gcatacgcta tagaagctcc
    26881 aaaaccacta gactagggca acagcatggc aaggcttacg cctctaaatc atgcagagcc
    26941 ttactaatct gtgtctctaa agcctgaaaa tcaccagtat tatcaatcac taaatcagca
    27001 taagctcttt tctgagacat cggcagctgg ctagcaatcc gctgcctagc agctagctct
    27061 gtcaattgat tacgcttcat caggcgcttg agctgagtct cctcatcaac atagagcagc
    27121 caaatagcgt caaaccaatc ctgatagccc agctcaacta aaagcggtaa atccataaag
    27181 aaaatagcct ctgtttgaga tagctcctct ttttgcttgg ctaaggcttc cctaatgata
    27241 gcattctgct gctgggaaga tttcgccata ttttccgaat gagcaaacag cagctccgct
    27301 agcttaggtc tgtctaattg ccccgatggc aataaaatat cctgtccaaa ggtctctagt
    27361 aggacctgat aaagcttgcc gccctttttt tgcagctcat gcaccacctg atccgcatca
    27421 atcacctggt agcctgcttg tctgataagt gcgacagccg ttgattttcc ggaggcaata
    27481 cctcctgtaa tgccaattac ctttgtcatt gcttctgaca cctaggacag acatgtgtcc
    27541 ctcttcctcc aaccttgagc tttacaatgg aggtcccgca gcgctgacag ggcttgcctg
    27601 tttggccata gaccatcaaa taatgctgca tactaccatt cattcctaag gtattctgat
    27661 aggttctaac cgtcgagcca cccttttcaa tacctaattg taaaatacga atcgtttcat
    27721 catgaatccg tttgatttct gcctttttca ggctagcaga tcgacgctca gggtgtactc
    27781 tagctgccca tagcacctcg tccacataga tatttccaag accagccact aaagtctgat
    27841 ccaaaagatg aggcttaatg gtctttttag aggctagcag agcagcctca aaggtcttca
    27901 attgaaaggt ctgcttcgtc ggctcaggac caagctgacg cttctggaaa aaagcagcca
    27961 gctcagcctt tggtagcaaa tcaaaggttc caaactttct cacatcttgg taaaccagcg
    28021 tggagccatc agtcattgtc aaaaagacat gaaaatgctt atgctcaggt accgtatcag
    28081 gaaacaagag gtatttcccc tccatacgca aatgcgagat cataaccagc tggccaaagt
    28141 caaagagcag gtacttcccg cgacgatcta ccccttgcac ctgctgccca gggatcgtca
    28201 tcacaaaatg ctcaaggtct gttttgacca tcttgggcac cctaaccgtc actgctgcaa
    28261 tctgcttgcc aacgactaag cgctcaagcc cgcgtcgcac tgtctcaacc tcagggagtt
    28321 caggcataat taaagatacc aaacgcgcta acaaagaaac cacataacca aaaccagcag
    28381 aaccagccag ttttagcact ctttactcag tctcaatgtt acaaacacgc ttcctttcta
    28441 taagctacta ttagaaagcc ccacccaaaa cctcaataag cttgagcaca aaggactatc
    28501 ctttgataag aactgttatc attcttattt tacgcataat ccataaagaa agcaactctc
    28561 acgaacagcc tttgcagtca ctgccgctat agcatcagaa aagcacatct cgcccgccaa
    28621 tccagcaagc aaagacaaag cccctgagct agcctattgt ttgccagccc aagggcacgt
    28681 tgtggccttt agtgtctgta aatagaaaac caagcaatgc tgcaagcctc aactgacaat
    28741 gctaggtctg atcagtcctg tcatcagctt gcggataatc tatactaatt ggcctatcaa
    28801 caagacggat actatcctgg taaacacctt ctgtttcaaa aataacaatg tcatttaatc
    28861 ccttgttgaa atagcccttt ggaatataaa gggttaataa gggacccact tcccaaaaac
    28921 gaccaatagg gtgattgttg ataaagacac aacccttccc aaagccagtc atatcaatat
    28981 agcttgcctc aggctcatga cattcaaatt gataatgata aaagccgggc tgcccctcgt
    29041 aaaaatcgcc atcaaaacaa agctgagaca aatcatcaag cggcagacaa tacatctccc
    29101 aattggtcac aaagtgcaag tcagccatca taccacgtcc tagaccctta ctttgactag
    29161 gtgctgtcag cttgtgccca taattgaccc ggcccatatt ttcaattaaa acatcgacct
    29221 gactcaaggc atgctgctgg ttaatgatga tatcatcacc aatcgtctcc tgatactgtg
    29281 ttgcaacctt ttgaccatct aaaaagacct gtgctctatc tctactatca atcaagcgta
    29341 aacgctcgtc ctcacgctta tccttcaaaa gatgtgtccg atacaggata tagcccgttg
    29401 attgccctaa agcctctatg ttactaggat agcaagcagt ctgacagctg ctgatgtgct
    29461 ccagcgtgct aaacagacta accttgtcct tcagaccaat cagaggcagt gacatcaagg
    29521 gcttaatcaa gggaggagta acctctatct ctgaaagctc cgcggtcaga cgcttttgaa
    29581 tcgcgtaaaa cttagctgtc ggattgccag cctcatctag gatagcgtca taatcatagg
    29641 aggtcacctg cggaaggtcc aattgctttc tggcagagca gccattcata aacccaaagt
    29701 ttgttccccc atgaaacata tacaggttaa tactgccctg cgccaaaacc tccatcactg
    29761 cgtcagctcg ctcttcaggg tcgcgtttga tgatgggctc atgccaacga ttgaaccagc
    29821 cgtcccaaaa ttccatacac attaaaggcc aatgcttgcc atgctcagaa aagaaggcct
    29881 gcatgtcagc aaaattctcc tgtgcccttg agccaaagtt gccagtcaca aagacatcat
    29941 cttcaatcag actaccagct ctaagagtgg ctcgccaagg accatctgct gtaaacaagg
    30001 gcgcactgag gtgctcctcc ataaagccct taacagctgt taaataggcc ttatcctctc
    30061 cataggagcc atattcattt tcaagctgaa acatcaaaat attgccgccc tgctgccatt
    30121 catgccttgc tagtctcggc agcagctcct cataatagcg cctcacatag gctaaataga
    30181 caggatcaga cgacctgata tgacaattct ttgtcagcag ccaagcaggt aggccaccaa
    30241 attcccattc tgcacaaata taaggactag gtctgacaat agcatagagc cccaattgct
    30301 gcgccagcgt caaaaaggct tccacatcta attggccaga gaaatcatag ctttcctccc
    30361 tagcctcatg taaattccaa gggacatagg tctcaaccgt attaaatccc agtgccttta
    30421 aattataaag cgaatgatac caatcatctg ggtgaattct aaaataatgg atagcccctg
    30481 acaggatttg cagcgatcta ccatctaaat aaaactgatc tgaaatctga aaacgttcca
    30541 agcttaattc ctcacttatt attgctatta gcctactagg cctcattgct gagcggcttg
    30601 gaatggccca ttctagcaac agcgaacagg ccattcagca gacaggctaa cttatcttat
    30661 ggtaacaatt gtaaacacta tctacagtct gactcctcat gctatgctgt cacagcagca
    30721 ggataagaga cagtgtatgc cttgtcatct gtcaatctaa tcccatattt ggtttcaaca
    30781 atagtatggt caaactgcgg taaaacagtt atcggtcctt caggcatact ctccagagac
    30841 aattcaaata tcgctgtgtc tgtgccatct cctgaaacat agctggcaag cttatctacg
    30901 ccatttacag taactgctaa ctgacgatca ccaagaataa acatcggttg attaaaggtc
    30961 atctgaatgg ttatgcttac tttgccattt tgctttggag ctgctgacgt tattgttact
    31021 tcttcaattt cagccttatc ctcacgaaac tggtctgaga tcatctgctt gatattaaag
    31081 gttgaatagg tgatctgacc actatattcg tataacaaac caaccctctc gtcgtctagt
    31141 tgaaccaagc tagagtaagc aaaacgcttt ggctcaaaaa tggttgaagc gacccaatga
    31201 atgctatcgt cctctaagac ctcaccgaca cgcagaatcc ctttcatgcg ctgatttcta
    31261 atcgtcagtt gctcacctga gggctctcct aaaggattgg ataaaacaac atattctttg
    31321 ccatcaacca tcatatgaat agctgacaaa ttgacataag gctctgggag gtctgtgatt
    31381 gtaggattat cgtcccaagt cataccatag tctgtgcttc tggcaataac gattgtcttt
    31441 ccggtattgc gcataaactg taataagtga ccattgttta gctgaatgat ttgattttct
    31501 gtcaattctg tgactgatgt atcaaaatcc ttagaggttg tttgttggtt atgaccataa
    31561 attctgccat catttggtga ttcacctcgt tgccatgttt gaccgccatc atcactaaaa
    31621 atattagcac tgctttgacg acctagacta gctgatgtcg cattttgttg attggtatag
    31681 taaatcggga aaactaaccg tttcacctgc tcaccctctg cattgactgc gtctatttca
    31741 atgccagctg cggcacccgt acctaaaaat cccatccagt cttcttttat ttgtggggta
    31801 atatcaagag gtgtggacca ggtttgccct tcgtcttcac tggttagcag ccataaaaag
    31861 ctggtcatgt aagtaaatag aggagctgtt tgtgagcctt ctctagtgat gccttgctta
    31921 gtgcgaccac ttctcagata aatattccct agtagaatat cctctcctgc ctctgtttga
    31981 tagaggttgc cgcgtgtgct aaaggctgtc tcaaaattgc cctcatcaac atacatatct
    32041 gtctgatggc cactctggtc atagacgata ccaccttcac gcacagtgta tttattattg
    32101 tcaaaatcat aaagatttaa ataatactga ccgttaatca attcatatcc tgagcctgct
    32161 ttagaagcaa cagcaccctg tgactcagga aagacatcta ccagcaaata aagcttgcca
    32221 gaagcgtctg ttagcaaggt ggagtctatt gaaaaagcag attgagtcat gttggtattc
    32281 caatcagcca agctatattg tgttgtaaaa taaggctgag ttggcatatc taagaccgta
    32341 atgttattac tccaggtttt gccatcatca tggcttatcc tgacaacagt tgcaacatct
    32401 ccccagtcat tgtagtgctt ctttcttgca tctgctgcgg ctatcaaggt tcctgatggc
    32461 gttttgacaa cagagggaat ccgatattca aagacccctt catcatattt gtcccaaaca
    32521 ttcgtctttt caccagtaac tggtcgaagg gttggctgat gagccttggc aatatctgtc
    32581 agatcataca catctgtatc aatcagcacc tgatcaacca gtccctttaa cccccagtga
    32641 aggaccgact caccatcata ggtgcgtttc aagcctccaa ttgttagcgt atcagcagaa
    32701 gccttccaag gtaattgctt cataaaccca gcaaagtcag cttccccata taagtcacca
    32761 ttcaagtaaa tctttagcct agaccctgta aagacatagc tgatcgtctg ccagtccgag
    32821 ttcgttaata aattaaagcc tgagccaact tttacaatcg gaacctcagc tcctttaaat
    32881 tcaagaccta ttttattgtt tttaggctcg ataaagaaag aggcgtattc attagctgat
    32941 gcttgatttg agatcgataa caaggccaag ggcgatgagc ttctcactgt tgtatcagca
    33001 gtatctagac ggtatctgat tgttacagtt ccttgggtta ggttcatcac atcgtctagc
    33061 ttaccaagag cctcgtcatc tgttacggct gctttttctg ctgttgcgtc caaaatagca
    33121 ttgcctaaat caactaaaat ggatgcttga tctgagattg gctgatctga gatatagctt
    33181 gcttctatgc ttgtataaac agctcgtccg ccttctgtgg tgtatttgat ctgataatgc
    33241 tctgcacttc ccaagatctc ctctggcgta acccattgcc aattggctgg cagggctact
    33301 gtagataagg gttctccctt cttaccaatc agaccttctt taggtaatac agttaaaata
    33361 gctacttctc ttgcaatctt agcagttggt gttactgttg agcctaaatc agcattgtaa
    33421 ggaacagcac tatagtaaat gttataaata ccaggagcta gctcagacaa ggctgacaaa
    33481 tcatctcgac cagcagcctg taaagcagca ttggtatttc cacccttgtt agtaaacaag
    33541 tattcatttt caactgaaaa atcaaccaca tagccttcct gatcagtggt tacagcttga
    33601 gctaaatcag gactggttcc ctctagcatg gtcaaatcct tgaccccctt gagaactggc
    33661 tgtgaggcat aataagcttc tgaggctgct ttttgctcag catcttggta ataacgcaca
    33721 taatcaatca caaaggccgt ctcatctgaa gctagatagt agcctgcatt tttactccaa
    33781 ttgcctccag tagcaaggtt aaactgaagg tattgaggct tattaaaggc agctgcggca
    33841 gcctctaagc gatcatcacc ggttaaatac atggtattat aaacaatccc atcaacatac
    33901 cattcaatct tatccggata ccaattaata ccaaagatat ggtagtcatc ataaaagtca
    33961 tcacttaatg tcagattgcc acccaatgct gttgggctat agcttccatc tttgtctgca
    34021 tcacccttga tatagtaaaa atgaggggtc ccgtaaactg ttttgttgct ttgatcacct
    34081 tcggcaagct caccctcatg ctctccgtta ggagcaccga ttagctccat aatgtcaagc
    34141 tcacctgtgc ttggccagcc atagccttga gttgacgcaa tatcaccatc taaggtaaaa
    34201 tcagccccca atgtccaaaa ggctggaaag gctcccttac ccttgggaag cttggcccta
    34261 gcttcgatac gaccatataa aaattcttgc ttgccaaccg ttcgtacgct tcctgaatca
    34321 taaatgacct gacgtgcgct tgttcctcct ctaggattgg cataacggtc ctccccataa
    34381 cgctctgtga cgtttaaaac aagattgcca ttatcaagat agacattctc tgtgctgtct
    34441 gtgtagtgct gctgctcatt cccgcgaata cttcccaatt catatcccca gttctcttgg
    34501 tttaaccgat ctcctgaaaa ctcatcctgc caaatcaatt cataatcatt ttcctctacg
    34561 acactcacgt tatcaatact agcagaggca gccaaggctt ccggagaaga ggcttccaac
    34621 catttgacta agccaacaaa ggtttctgaa gtcgttgctg taaaggagag cttgatatgt
    34681 gaccaagtac cgtctgtatc tgtgaggctg acctctttga taacagggcc ctgaagattg
    34741 tgattggact ctttagcggt aaggtataag ccattatgag gtgtgtcagc ttcaaccttc
    34801 acatcagcct ctagcgtata ggttttccca accgttgtag acaccttttg aaggatatgc
    34861 tcatctaaag tgccgcttgt tacctcagca tagctattac cattctctgt tgtgaggact
    34921 gaatgacctc cctctctata ttgccactga ttcttattgg acacataatc attgtcaaaa
    34981 ccaccattag ccaccttatt gagctcaatc ggagcgttag acttctcttc gtctgctgtc
    35041 tgatcagcag cattgctggt cacagcatta gctactactg cctcatctac tgtcgtctcc
    35101 tctgagacta ctaaggcctc gctatctgta tctgtagctt gaggctcctg ctcatggctt
    35161 atctctgtta ctgctgcttt cgtaggctgc tgcaggctta cctctgaaac gtcatcagca
    35221 taaacagcca ctggcagacc agcagcaaga ccaataccca cacacactga agcaacaccg
    35281 acactaagct ttttgatggc atattttcta atttgctctt ttccgatagg attaaataac
    35341 atgtttattt cctcacttat atatacatca tttttaaaca caatagcttt tcaaaggccc
    35401 atttagccta atccagtgct ggtcaggcta acgaccttgt tataaaaacg ctttcaattc
    35461 agcgcttaaa agaagatata ccagatgaaa ccgatatatc ctctcacaaa gtgactaacc
    35521 tgccttttca agctcattat cagccatctt aacaaatgga aggtaaatca gggttgccaa
    35581 ggccaaattg acaagcgata gcacaatagc acgccaatca aaaccagttg aaaagaagcc
    35641 atacaagaca ggcggcatta cccaggtcac attttgcgta acgggtgcaa ccaagcccag
    35701 actagttgcg atataagcaa cacttgacat aacagcagga caaacaataa acggaataaa
    35761 caacaaagga tttaaaacag ttggtaaacc atacatcact ggctctccta tattaaacaa
    35821 tacaggagca acacctagct tagccacctc acgatagtgt tcatttttag acttccagaa
    35881 aatagcaatc aagagcccta aggttgcata ccatacaaag aacactcgtc caaagataag
    35941 gaatcgcctc atgcttttga taagcctcca aattagccaa gagggcaaca ccaaatactc
    36001 cctccatatt tggcgccata acattgccgc catgaatccc aaagaaccag aaaaattggg
    36061 tcaaaacagc taccaaaaca acagcaataa agctttgtga taagcccaaa agtgggattt
    36121 gcaagacctt atagatccaa tcaatcatca aagaacccgt tagcttttca aagacaaatg
    36181 ttaaaatagc tacgctatac aaggcgcaaa agcctggtat gatagataag aagggcttgg
    36241 ctacagcagg tggcacacta tctggtaatt taattgtcca attttttaac attaatttac
    36301 aaaaaataat agaggctaaa aagccaatca taattgctgt aaaataacca ttggagttaa
    36361 tttgcgcacc aggcaatagg cctgagatgg tcacattaag tgagctgccg ctgacagtaa
    36421 caccactgtc cttaaaagcc gtcacaagat caacaccctt gagacctgac gcgtcaatgc
    36481 tagaggtaac agaatcccca atcgcaatca caaaggcagc taaagaaacc aaacctgatg
    36541 agagcgtatc tgtcttataa agtttagcga cattaacccc taagcaatac acaaatagca
    36601 aggacacaat cgaaatgctt cccttaaaga caaggttgtt gatggttacc caccattgga
    36661 aggcctctgt aatgccttgc aagccaaatt ggtctggaat atccactaaa aaggcattga
    36721 tcaacagggc aatagagcct gtcatcacaa ccggcatcgt tgcaataaaa gaatctcgca
    36781 aggccactaa aaatcgttga ttaccaatct tcgtagcaat tggcagcagc ttttgcgaaa
    36841 gaaagttcat atagttattc attcatagct ccttaaaaca atcataaaac agctaagata
    36901 gagcagtaaa ggctctctct aacagcttag ccttcatttt tagtttgctc gctcgcctgc
    36961 catcttcttt ccacattaat aataaacggc aagtaaagaa gaatatctag aataattaaa
    37021 acaagctgta ggactgaggc ttgccagctg cccgttgcca aaaatcctga aataacaggc
    37081 ggcatggtcc accccggatc agcataggtg ccaggtacaa tgccagaagc aaaggcaaaa
    37141 taagcgacaa acaaattcat aacaggtgct agtacaaaag gaataactgt caatagattt
    37201 aaaacaaccg gtaagccaaa catggtcggc tcgttaatgt tgaaaaaccc tggaatcaag
    37261 gtcaatggtg acaagacctt tgcctgctga ctagccttgc gacgacgtgc taaccaggct
    37321 aaagccaaca ccaagccaat ggttgcacca gctccgccga taaaaacaaa gttatccata
    37381 aagacagacg taaagacatg cggcaattcc tgaccagcct tatgagctgc catattttca
    37441 gtcaagttag ataaccagat cggcttcata ataggattgt ttaggacatt tccaccatgc
    37501 acaccacaga accataaaaa gccattaaga agaacaacga taaaattacc aaataaggta
    37561 cttcccagca agccaaatgg aactcctagt acggacttaa caatgtcatg gacatttggc
    37621 aggctaaaat gatccaagaa agcataaaca gcaagccaaa acacaataat caccgctcca
    37681 ggaataatgg cgctaaagct ttttgatact gcaggcggca caccctcagg catcttaatc
    37741 cgaatatcct ttttcataaa ccattgataa gcatagccat ttaccaatcc caaaacaatg
    37801 gcaacaaaca agccgcctga tgaaaggtaa gaaggcgcaa tacccgctac ctcacccaag
    37861 gctttaccag attcattgac aaatgaaaca gtaaatgggg tcactgttaa aaaggcagag
    37921 atattaataa tcccagcaga aatcccgtct gccttatact gcttagccaa gctataagaa
    37981 atcccaaagg ccgcaaccaa ggcaatcaga ttaaagctcg aatctactcc cttccacaga
    38041 taggtagaga caccaatctc accaagccaa gcttcccaac caggaatcgg caggctagca
    38101 atcaccatta aaaaggaccc aatcaaaatc aagggcatag cgtaggtgat cccatcacga
    38161 atagcaataa gaaagcgatt gcttcctagg cgaccagcaa ctggaacaag cttttgctgg
    38221 ataaaatctt caaatttagt cattgttacc tccttgtgac gttaaccttt cataaataga
    38281 tactagctcc cttgccaaat caacaaaggt aatactagtc atcaaatgat cctgaccatg
    38341 aactaatagt aggcttactg gtgtagcatt tccccgtgcc tcttgagtta gcatatctgt
    38401 ttgtgcatga tgggcctgca ccaatgcctt atcggcctgc tttagacttt cctgagcttg
    38461 attgagctct ccctttttag caaaagcaat cgcctccatc gcaagcgact tggcactacc
    38521 accatgcatg atcaggccca taatcgtctc tagctgctta tcttccatga ccaccaccta
    38581 tttcatcaaa ctttcagcta aggcaataac cttatcacca ttcatcatac cgtaatcaac
    38641 cattggcaca accgccactg gaatgtcctt ttctgccaag ctttcttgaa atgctgacaa
    38701 ttgataagca acctgtggcc ctaataacac cacatcaaca ggatggctta gagcgtaatc
    38761 ctctgcctca gtcaatggca atgcaaaaat atctgcctca agcccccgat tgtcagcagc
    38821 cttttccatc tttgtcacta atagactggt actcataccc gctgcacagg ccaacataat
    38881 ttgtttttta ctcatgatct tctcctttat cccaaatcct aacgtcgaat agagcgcgac
    38941 attctcacaa tggtatgtct ttttcctcgg atagcgtcac taagagcaaa gatattttcc
    39001 actggcgcaa tcccgctata gccagcatct ccgatatgat gaatatcgac accacagatt
    39061 ttattgcgaa tagcaatgtc tcgaacgatc gtagtatctg acccttcctg actcgttcca
    39121 atagctgaca taactagagc atcgtgagca tgcacctcct caacaatagc tctaaggtca
    39181 ccctctgtaa agccaggaac tgtcccaaca gcaggaacta aaatcacatc agccccagcc
    39241 tcgataaacc gccgaacagt ttctaagtca atcaccgctt cattagagcc agcagcatgc
    39301 atctttccag caataatcaa gcctgaaaaa tagtgcttgg cctgttgaat agctctttca
    39361 atctgattat tgctaacacc agtacctgga tttcctgtca agcaaacaaa gtcaaagccc
    39421 aaggcttcaa tctcttgaaa ggtcttagct gtcgcctgtc gcccttctac tagctccaag
    39481 cgcttttcag tcatgtcaac gtccaaatca attggttcta aattaacacc aattggacgc
    39541 cccaccagac gacgcagctc taaaataggc tgatcagtag caggtagacc agatatttga
    39601 acatcaaaga catctacaca attcagcaaa atcaaatcag cactaaaggc tgcggcaacc
    39661 tcagcgttcg taaggtcatc tccagtccaa gagggtcttg gcgctacatt ttctgagaca
    39721 atggtacgtc cctcgcttgc cttaatggct tgctttagct ctaacgatgt taactgtagc
    39781 atttctgagc tactagcact caataatcgt gttttcatcg cttctccttt atttttattt
    39841 taaaaacatt aacaaaagat aaataagatt taactcttat ttgtttactt tttataaaca
    39901 aataaagtat attctattta ccaatatttg tcaacgtttt caggcaggat ttttaattct
    39961 tttttggtat gatagaggta cgataataga ggttactatg aagacggata aacaacaaga
    40021 gctttacgca aaaattttag ataccattta tgcccaacgg cctatttcac gcattgatat
    40081 ttcaaagcta acgcacatca cacctgctac agtaggggct atcactaaag agctgctagc
    40141 acaggggtgg atacacgaaa tcggagagct gacggaccac tccgttggcc gcaaaaaaat
    40201 attacttgat gcttcggcta acgcctttta ttttgctggt gtcgaattgt ccgaaaagca
    40261 tttctatttg gtcattacag ataacctggg caccatctat gccaagcaca accaacagat
    40321 cgacccaagc atttcctcct actacaaagc agactatatc tctgagctga ttcaagcctt
    40381 cctcaagcag cacaagcact atgatgtaca agccatagga atagcactgc ctgggcatta
    40441 cgatcattcc acctccagct caacgcatat taacaccaac aatcccatct ggcagcaggt
    40501 cgatttaacc gcaattgcga agtccttccc tattccagtg gtctttagca acaatgctca
    40561 ctgtatgatt attgccaagc gcttatacga gcgtcaggca cataatcaca attttatttt
    40621 ctttcatgtc ggacgaggca tgcactgctc ctatatgtat aagggggtca tttatagccg
    40681 tcacaatgct gttgttgggg aaatcggaca taccattgtc aaccccactg gagagctttg
    40741 tgaatgtggc aaaaaaggct gtttacagac ctatgccagc aatgcctggt tgctcaaaaa
    40801 agcaaaactg ctacatcagt atgcccccaa ttctcatcta agaagccttg tcgataaggc
    40861 ctgtgagctc aagctagacc atctcttgat tgcctatgag cttggtgatg tcggggtgac
    40921 cacgctcatt cacacagcta ttgattacct tgttttatcc ctgtctaacc tctccttact
    40981 gattgatacc gagcaaatct atctccatgg cagatttatc agccatcctc ttatatcctc
    41041 caaaattctg caagccctgc aaaatgacat taagcttctt agcaatcaaa aaaagccaga
    41101 aatcattgtc atgccttttt ctgtctataa tgccgctgtg ggagctacag gcttatgtat
    41161 agatgagctt tacctcaatt ataaaaacaa atatgattga taacccccac accaatatca
    41221 gctaaagctt taaagcccat ttgagaagct atttctcaag tgggcttttg cattatgcga
    41281 ctttcagtcc atctcgctcc gcaggtgcga gacaaatgat aaccataaaa aaagagaggc
    41341 acttggttct ctctgttcta tcctaatgcc ccatttgaaa ctcaccagca aaatactctg
    41401 ccagcatcag tctatgcttg tctgagattg aagacagctc tgcaatctct tctctagaaa
    41461 aataaccgag ccttaaggtt tcatcatttt gataatcagt gatagcctta tctgccttgg
    41521 ctataacctc ataaagcatc acaacggtct gaaccttatc accatttgga taggtctctt
    41581 caaaattggt ataaacattc aacaaccgta aaggctctac tgtaatcccc gtctcctcat
    41641 aaaattcacg cctgcaggtt tcagcagaag actcacccag ctccatggca cctcccggaa
    41701 ttgcccaggt tttcttatct gcacgtagct gcaaaagcac cttaccttcg gcattggcca
    41761 aaataccacc agcaaaagtc agaataatgt tatcatgccc cacctttgag cgaatatagg
    41821 aaatatagtc ctgtgtcatc gtaactccct tcattgccat cataagatta aagccagtca
    41881 gctggcgcaa ttgctgcttt tttgccaacc aataagcaat gcaggctttg tctcttgtcc
    41941 ttgataggct ggcaaagcat atagccctaa tttttcaacc tgattatatc acacttttta
    42001 aaagccagaa agagactcga atgccaagtc ccttttcttt caatctataa ccaacctcag
    42061 aaaaactcag acaagctacg ataacttttt taatgtcttc tttggccaat ggtttgcgac
    42121 tggtcattga attactttca atattatccc catcatcaca tgataaccac aaataaacac
    42181 gtacttgtgt cattgccttc tcctcaatca gtagtaggta cctactgttt ttttgattga
    42241 ttgtacctat aggtgttttt ttccttcaaa atctttaaat aaaataccct ttataa
//
LOCUS       DARYLJ010000013        41243 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYLJ010000013 DARYLJ010000000
VERSION     DARYLJ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41243
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            398..811
                     /locus_tag="TU746_000635"
     CDS             398..811
                     /locus_tag="TU746_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0891005.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1071..1652
                     /locus_tag="TU746_000636"
     CDS             1071..1652
                     /locus_tag="TU746_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL0891006.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2062..2388
                     /locus_tag="TU746_000637"
                     /pseudo
     CDS             2062..2388
                     /locus_tag="TU746_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2457..4460
                     /locus_tag="TU746_000638"
     CDS             2457..4460
                     /locus_tag="TU746_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891007.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4457..5065
                     /locus_tag="TU746_000639"
     CDS             4457..5065
                     /locus_tag="TU746_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0891008.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5254..7980)
                     /locus_tag="TU746_000640"
     CDS             complement(5254..7980)
                     /locus_tag="TU746_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL0891009.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7995..9281)
                     /locus_tag="TU746_000641"
     CDS             complement(7995..9281)
                     /locus_tag="TU746_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL0891010.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            9414..10472
                     /locus_tag="TU746_000642"
     CDS             9414..10472
                     /locus_tag="TU746_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0891011.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            10487..12181
                     /locus_tag="TU746_000643"
     CDS             10487..12181
                     /locus_tag="TU746_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL0891012.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            12208..13599
                     /locus_tag="TU746_000644"
                     /pseudo
     CDS             12208..13599
                     /locus_tag="TU746_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            13586..13723
                     /locus_tag="TU746_000645"
     CDS             13586..13723
                     /locus_tag="TU746_000645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891013.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(13919..16093)
                     /locus_tag="TU746_000646"
     CDS             complement(13919..16093)
                     /locus_tag="TU746_000646"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL0891014.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(16081..16974)
                     /locus_tag="TU746_000647"
     CDS             complement(16081..16974)
                     /locus_tag="TU746_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0891015.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            17186..18136
                     /locus_tag="TU746_000648"
     CDS             17186..18136
                     /locus_tag="TU746_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0891016.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            18146..19072
                     /locus_tag="TU746_000649"
     CDS             18146..19072
                     /locus_tag="TU746_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL0891017.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            19156..20601
                     /locus_tag="TU746_000650"
     CDS             19156..20601
                     /locus_tag="TU746_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0891018.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            20949..21554
                     /locus_tag="TU746_000651"
     CDS             20949..21554
                     /locus_tag="TU746_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL0891019.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            21544..23268
                     /locus_tag="TU746_000652"
     CDS             21544..23268
                     /locus_tag="TU746_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0891020.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            23268..24752
                     /locus_tag="TU746_000653"
     CDS             23268..24752
                     /locus_tag="TU746_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0891021.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            24766..28209
                     /locus_tag="TU746_000654"
     CDS             24766..28209
                     /locus_tag="TU746_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL0891022.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            28360..29244
                     /locus_tag="TU746_000655"
     CDS             28360..29244
                     /locus_tag="TU746_000655"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL0891023.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            29370..30143
                     /locus_tag="TU746_000656"
     CDS             29370..30143
                     /locus_tag="TU746_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL0891024.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(30475..31557)
                     /locus_tag="TU746_000657"
     CDS             complement(30475..31557)
                     /locus_tag="TU746_000657"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL0891025.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(31616..32371)
                     /locus_tag="TU746_000658"
     CDS             complement(31616..32371)
                     /locus_tag="TU746_000658"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL0891026.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            32809..32979
                     /locus_tag="TU746_000659"
     CDS             32809..32979
                     /locus_tag="TU746_000659"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891027.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            33886..33956
                     /locus_tag="TU746_000660"
     tRNA            33886..33956
                     /locus_tag="TU746_000660"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33918..33920,aa:Thr,seq:ggt)
     gene            34484..34738
                     /locus_tag="TU746_000661"
     CDS             34484..34738
                     /locus_tag="TU746_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL0891028.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            34760..35260
                     /locus_tag="TU746_000662"
     CDS             34760..35260
                     /locus_tag="TU746_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0891029.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            35520..36104
                     /locus_tag="TU746_000663"
     CDS             35520..36104
                     /locus_tag="TU746_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0891030.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            36304..36867
                     /locus_tag="TU746_000664"
     CDS             36304..36867
                     /locus_tag="TU746_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL0891031.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            36880..39531
                     /locus_tag="TU746_000665"
     CDS             36880..39531
                     /locus_tag="TU746_000665"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL0891032.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            39744..40232
                     /locus_tag="TU746_000666"
     CDS             39744..40232
                     /locus_tag="TU746_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL0891033.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(40435..41217)
                     /locus_tag="TU746_000667"
     CDS             complement(40435..41217)
                     /locus_tag="TU746_000667"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891034.1"
                     /translation="MSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYDDYTEAP
                     QIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDKETELVQ
                     VQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASNGDKFRV
                     HITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKEREHSQK
                     RVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
BASE COUNT        11344 a         8277 c         9597 g        12025 t
ORIGIN      
        1 gaaaggagtg ctttcaaatg ttatcagggg agcatgatgg ctaaagagag acctcagagg
       61 aaactcagtc tttgaagcat taagacagct ttctcatatt ggttacgggt attagaaatg
      121 cgcttaatcg gtgtcaacag ttttcgtatt accatttaag acgtttcgac gacattttaa
      181 gacttaaata ctgaaagcag ctggtaatat gctatactgg tgccagttgc taaacatagg
      241 aaatattcat gtggacgaca gcattgatga aatatttaat gcttaggtac tggtagactt
      301 gcttatgttg aggctgaaaa aattaataga gtttgtgacg cagctattgg aggaataggt
      361 ggcgcactga cttgctaaga aagggcaagg tgttgtaatg cttaataaaa tgaagcgact
      421 acattatttg atgattttta ggctattaac tggtcagcta ccagctatta gcttgatggc
      481 tgttcttctt tcaaaagaca ttcataggct ttctttggga tcactgatta gttttgctat
      541 ctttgcggta agcactgctg cttctaatta ctatttttca cgagaaattg cgattgagca
      601 gttgaaggaa caaacacgtc ccaatctgtt attaactcag atcctgttta tagtggtgtt
      661 tatgattata ggcattgtgt caatctattg tggtctaagc tcgtctgagt tttataagca
      721 ggttattgct gtgatatgct cttttatatc atttgtcact atgggattga tgatttgggg
      781 gatcagatac gcaaaagctt atcgtcgtta atagcttgag gtggtactgg tacttgaaat
      841 cacctcctta accagttaat cataagctat agcactaggt atcagcctta aagcgacgat
      901 acctagtgtt tgtgtgctca aacgcttaaa atagcttttg agggggtaga gctgtctatc
      961 tgcaagcgat atgacaacct atttcattta gggatcaggc ttttttacta tcagtgtttt
     1021 tgacaaggcc cttgttttgg agtatactgg gaaaactagg agggctatta atgcgtagga
     1081 ttcgtttagc aaccttagca gatgctaagg ctttacttga tatttaccgt ccttatgttg
     1141 aggaaaccgc tgttaccttc gagtacactg tacctagctt gaccgagttt gagcgacgtc
     1201 tgtctgacat tatggtcttt tatccctgtc tagtagtgga agaggaggga ggcattttag
     1261 gttatgccta tgctagtcgc tttcatgcac gcgcagccta tgcttggtct gctgaggtga
     1321 ccatttatct ggcccaggag gctagaggga gaggcttggg atcagccttg tatcaccgtt
     1381 tggagggtta tctgaaaggt atgggaatct taaattgtaa tgcctgtatc gctagtacag
     1441 cgcatgctac gccttatctg accaatagca gtcaagtctt ccatgaaaaa ctcggttatc
     1501 ggttggttgg cagatttcat cagtcgggct ataagtttaa ccagtggttt gatatgattt
     1561 ggatggagaa actgctggga gagcatgacg tacgccctcg cccagtgatg tcatttaggg
     1621 attttctttg ccagaagcac cagtctgaat gacaccttat aaaagcttag attaatacaa
     1681 aaggattagg tcctgtcaga ggaagctaat ttttttgtat tgtttgacga gaagttttga
     1741 ctgataaccg caatcataaa aaaactcttc aggccctgtt ataaaatggt ggtagcagga
     1801 gatggttatg tctgagcttg tcactaggtc agctacagca gtcctagtgt catagcttta
     1861 aaaatgagaa aaaagaaatt attttttaag cttggtcttt ttaatatctt tttttgccct
     1921 tgacaattct gccaatgagc tgcaaaaaaa cttaagctct ttcccaaaaa gcttttatga
     1981 tatgatacac ttgtgttgta aaaggatcct gatactagtt aagatttttt tactttattt
     2041 taacaaagga gagtacacga catgaaaaga agtgtaaaat ggtttatgag ccttggcttg
     2101 gttggagctt tcgtagttgc tgggatatct aatgttaacg cagagactag gcaccctcat
     2161 ccaaagtata aggacacttg ggaatttgga attaccagtg ctagctgatc ttactcaaac
     2221 gcttttcttg gagttcctat tgggctagga agtagtgctt ctgtgacaga cttttgggga
     2281 aatgtaaata gtaaagatag tcaaaacaat ggttgggctc gtgccggtgt aaaaaagcag
     2341 tggaattggg ttcaagcaaa gtcatgttat ggctggtatc aggtttaatg ttttattgta
     2401 cgttttagtg gatgaagata ttatcctctt agtcaacttt tctcaaggag gtttttatga
     2461 ggtggagagc tacagttatc tgtattttcg ttctgctttt gacatgttta tcatttggtg
     2521 cggtcaagga gtatggcaat gatatcaaat accctgttca ggctgcattt tcattagtgg
     2581 cttcaaacaa agatgttgat aagggacacg ttttagacag gatcgaagcc ttagccgagc
     2641 aggaacatat ccaaatttat cgtccctact tagatcatac tggtaaagaa gccacctacc
     2701 tgtttgggac aaatgggaaa aagactgtct atagcagtaa tcgcaaggag ctcttgacaa
     2761 acgatcttag tggcatgtac tacacgacga ggtctcttcc ttcatcattt gaaaccgcga
     2821 tgactgaacg gggcttgacc tacaaaggtg ctgatttacc ttggtatctc ttgccttatt
     2881 attttttgtt cacaaactta cgatccttag ctatttggac cctctttttt gtgtttgccc
     2941 tcctcttgtt tgctgttaaa ttgatgtatg ctaaaaagtc tatgatacta agaagcctgg
     3001 gcttatttga acactatagc cgcaaggagt tgctacagga tttgttgctg atgggagcta
     3061 gctttgcggt tagtattctc ctcttcattc tctatcaagg cagtatctcc aatgtttttg
     3121 tcaagtcatt tacacttctg atcttgacta atgctgtcat tttattattg ctgatgcttg
     3181 ctgttcatgc tttatttttc atcaatatcc gttcgttgaa ggcgctagcc attctaaaaa
     3241 ataaacaagc aacccctttg gtcctctttg tctggttggt ggggatttgt ttgtctagcg
     3301 tcatttttgg gctttcccta cacaaaagct tggagactat aggaaaatct gccaatgaca
     3361 ttcaagttct aggaaaatgg gataaagcta aggattttgc ggaaataaca tggctagata
     3421 ccttgagtac gcatactgat gacaatcacc aaattgatag tgattatttc aaggaagaaa
     3481 atcagcgcta tcaacatttt ctcctgtctt tttctgataa tgacgttatt tattcagcac
     3541 tttcaagcct taacgaaacc aatttacaat cagctcctga tgacttcaaa aaagagttaa
     3601 agaccaatgg ggttgatcca aggattgcgt caaaagtccg ttatgtcaat cagggattta
     3661 tgctaaaaaa taaagacatt ttccctaaca atgattacgg aaggccagca gctgatgctg
     3721 taggagtcat ttatatttct aaacatatga tgggagatgc tgacagcatt ttaaacattg
     3781 tcaattatga atggtttcaa tatagcagcc taaaggctaa tcaattggtt gttcaagagg
     3841 ttcctgacgg acaaaagagc tttctgttta atcataagca agaccaacaa gacatttttg
     3901 ctcagcaaga agaagtgaat actatattag tgcagttaaa cttttcgttc atgacggagc
     3961 catcattatt gacgaagttt ggagaaatgg ctcaaaaatc tatctatcgt caggcgctta
     4021 ttcgtgatcg attaacacaa gcaggcttga cgaatttctc tagtttgacc aatgtttcca
     4081 atcatttgat tttagagcgc cataaaatcc taagccagct catcggaagt gttattgcct
     4141 taacggtcct tgccattgcc cagtgcttta tcatttatga atacattgtt tctctgatga
     4201 aacaaaaggc caaaaagatt tccgtctggt tcttgatggg gcaaaaaagc cttgttttga
     4261 ttggtagatt gttattgccc ttagctttgt gtttgtttct tgccatagga atgatgggaa
     4321 tccttactgg aaataggctc atggtactag gcattggcct gctttattta ggagaaatcg
     4381 tttgtatgtc cttttttgct tatcaggcta ttttgaagca tcggattcaa atcatcaaag
     4441 gagattttga catattatga ttgagataaa acagctttcc aaacattatg gaaaaaagac
     4501 aatttatgac aagcttagct tgacttttga ggccaatcgt tcttatgcac ttgtaggtcc
     4561 ttcaggatca ggcaagacca ccctattaaa tgctattgct cgccttgaaa agccagatag
     4621 tggtcagatt ttagtaaatg gtcaagacat ttggagcatg aaagagcaag attattttaa
     4681 ggattatttg ggctatgttt ttcaaaatta tgcactgata gaggaagaaa cagtctatga
     4741 caatcttaaa atgctggctc ctaaatctaa cattgtggaa gccttgcata gcgttggctt
     4801 agacagtagt tttctctcac agaacattta tgaattatca ggtggtcagg ctcagcgtgt
     4861 tgctattgca cgcctattgt taaaaaaggc ttgcattatt ttggcagatg agccaacggg
     4921 tgccttggac aaggaaacag gtgatgagat tattgagctg ttgcttagtt tggtgagccc
     4981 tgatactgtt ctgatttttg ccactcatga cccaaatgtg tttagccgcg ttgatgacat
     5041 catcgacatc tgtcatctac aatagaggca agctctgaga catttagtct ggactgtcga
     5101 gctacagcaa ttagcttgac aatgctgtta ttcctttgtg tcaggaagag attgctattc
     5161 ttctatagat ttttcgaata gacaatgctg aaagtcctta gcgttaatgc taaggacttt
     5221 tttgtgattt aggtcaaggt agtggtaatc tggttataga tgagctgatt cactcttttt
     5281 ccaagctagg gttaggattt cgcccttgcc aagctcagct ggtaggggtt catgctgatc
     5341 ctcttctagt aggctggtaa cccttgctgt gtggtctggg attgctaggg taagagcgca
     5401 ggccttgtca tttgatacat tatagctgcg cgtgattagg gcattatcgg ataggcgacg
     5461 cttgaaggct gtgagagcaa cgtgatcagt tgctcctttg atgtaagcat attgagctgg
     5521 cagctggcca gaatgcctct tggtttgcgc catggtgact ggtacctgag cctcctgagc
     5581 tcgccaatag ctggcaaagc gtgtggtagc gttaatgctt tcaaagctaa agctgacagt
     5641 ctgttgaccg aggcattgag catcaggggt tgggaagtag ccccaatctc caagctcacc
     5701 gacgcttcgt aggagcgtga tagcgatggt attggtatct ggtaggattt cgtattcatt
     5761 gaggccgtaa ttgcctacag tgacaccagt cctaccatca aaaaggctga caaaggcctc
     5821 ctgatgctga ggattggttg ggtttttcca gaattgggca ttggtatgat taggccgctt
     5881 tacggtttca aaaatactat ctgcaaaatg gtggtctgtc tttaaatggg ttgggaatag
     5941 cacgcgcaag cggtggtttg tcatttgatt gttaaagctg gtctgaaatt gtaggcgtgg
     6001 gctgtctttt tccatacgaa taactgttgt tactgtaaag ggcgcttttt cctgtgagcg
     6061 tttggcctga cgctctctaa tgtcaatgac agcctccatt tcagccttta gacgatcatc
     6121 tgtagctaag ggaatatcaa aggtctgtgt caattcgatt tcagcaagat aggctgtgtt
     6181 ggtcaagacc cgcaacttac agctcccttg atgagcaagg taggggctat catgatctgg
     6241 ctggcgaaag atatattcgt taccaatatc accacaatcc tcgtattgga gacagctgtc
     6301 aaacctattg ccatttagct tgtcttcaat cgttagaagg ccatttgctg cgatgatgac
     6361 ttttaggaaa tcattttcaa gacagctcct gtcctgatga aagagcattt tgtcagtgtc
     6421 agttgcttgg caaggctgat cagtctcttt tagtgcaaga cattgccatg acatagcaga
     6481 aagagtcagt gggagcctta gctgtacctt gatggcaaag taggcttctc tgaaggtgcg
     6541 ctctggcagg gcataatcaa aggcgatgtc tgtgcctaag atttcagcct cctctatgat
     6601 cctgccagct gcgtcaataa cctgaaattg tggctgtctt gtctctaggt attcctttgc
     6661 ttcttgataa acagctttag gcagtcgttg cccaaatgga aaaatcttcc atgtcagggt
     6721 gaggtcggag accgtttttt tctcatgacc gcaggtattg aagaggacaa aaggacagct
     6781 atcctctgga aacatggagg tatcaatagc ctcagctatt tggttggcag aacgctctgc
     6841 taagtaagtc cccacctcat aggctttatc aaagcgaggc atcatctcct ggtggacact
     6901 atcaacacta cagccacaaa tggagtcatg agggtggttt tgcatcaatg ttttccaagc
     6961 atagcgcagc tggtcgtgag gataggtacc tgtgacctca aaggccatcg tggcaagagg
     7021 ctctgtgata ttttcaagct gacgagacac tctggtatta gcctgcttga ggtaaattct
     7081 agcagaggca gtgttggcta aggtatacca gccgtccgtt tcttggctgg tcatctcacc
     7141 agacacaatt gagagctcct caggcagctc ctgacttaaa tcagccaaat agtcctcaaa
     7201 gcaagagtgg acaaagtcgt aatcagggta gagcttattt gcaagggcaa ttgccttggt
     7261 aacgtctagt tgaacaggct ggtgatcaac cccattcatc atcagcaggt gcctggtaga
     7321 agcaaagcgc tcagcgtctg ctagcttttg atcccagaat tgtcgagcct ttttctcctc
     7381 ggttgggatt tcgttgccat tgctgtacca attggcaaat aataagccga gaatgcggct
     7441 atcatcaggt ccctgccaga tcatttcaga aaattgggag ctgtattttt cgcttgtatc
     7501 cacttgattg ttaaagcctg taggcctgat accacgtcca aaggcagcgg catttagccc
     7561 tgcttttcgc attagctgtg gtgtttgtcc catatttccg aaggtgtctg gaaaataacc
     7621 cagtggaacg cttgcccccc attgctcaca gtcctctttg ccaaccagca tgtttcggac
     7681 attggactca ctgctggtca aaaaggcgtc ctgtaggata taaaaggggc caatacgtag
     7741 cttaccagcc tgaatggcct gtctaatctc ggcctcacgc ccaggcttga cctgcaaata
     7801 gtcatctagg ataatggttt gcccatctag atggaagcta tgaaaatcag ggtctgtttt
     7861 aaaaaggtct agtaaatcgt caattaactg gatcaagcgc atgtggtgct gctcataagc
     7921 catgtaccat tcgcgatccc aatggctgtg tgaaatgata tgtacttttt taggtgtcat
     7981 cactgactca ctttctaagg gctaatggta aagcccagat aatcaagaag aagctcacaa
     8041 aacatcatgt ttgcccatga gaaccattca cgtgtatagt gactcggatc attgacgtca
     8101 aagccctcat gcatcaggtg ggtgcctgcg tcagtagcca ccagtaaatc aagtatatct
     8161 gctttatctt tttgatcaag tgcagttaag ccctgaaggg caagtgcaat atgccaaata
     8221 tagtttggtg gcgtgtggga ggagccaata ccagaagcag cactgccttg gtaataataa
     8281 ggattttccg ggcttaaaat ggtttgacga gtggctaggt aaatagggtc gtccttggca
     8341 caaaagccaa gatagggtgc cgcaaggagg cttggaatgt tagcgtcgtc catgatagta
     8401 tagtgcccca ggccatctac ctcataggca tagatgatct ctccttggct gttggttaca
     8461 agagcatgct cctcaatccc tttttgaatg gcaagcctaa gtgcatgagc tctcctagca
     8521 atcgtttgat ccttaaagag atcagtatag agcccttcaa gataggataa gacgacagca
     8581 gcaaacatgt tggacggcac gaggtagccg tattggcagg catcatcgct tggtctaaag
     8641 ccagaccaag tcatgcctgt ataggcaaca ggagctccct taccgttgtg ggtcaaggta
     8701 tcctccttac gccaggtgtc gcgctcaaag ctgtaaggag aggcagtgtg gtcttgctct
     8761 gtgctccaga catcaaggat cagcttgatt cctctgtgga aatcctcatt gaaatgctct
     8821 gtacagtctg tctctcggta gagcagatag gctaactgga tcggatagca gagggaatca
     8881 atctcatatt ttcgttccca aatccaaggt cccatctggg tgtggtctgc ttggtggccc
     8941 ttgctatttt cctcctcgtt aaaggcgttg gcataggggt caatgcaaat gtaacggaac
     9001 tgacgtttaa cgagacctgc tatgatttgt ctcatgccag catctgtctt ggctaaaaag
     9061 agataaggct ttagttgcgc agttgaatca cgcagccaca tggcaggaat atcacccgtt
     9121 agaagaaagc tggtcccatc ttcgtcgatt tttagggtcg tttccaaggt gttggcaaag
     9181 ctggctttaa aattaatggc ccagctacgg tgctcttcac cgcagagctc ttcaatcgtg
     9241 tccataaacc tgagcacact gctaggaata ggtcttgtca tatcatatcc tcctaaaaga
     9301 tatatcattt gatatctttt ttaattataa gatataactt tatttttgtc taccacttta
     9361 gaaaaggttt acaagtcttt tttttcgtga tatactgcta gagggagtaa aaaatgactg
     9421 aattactata taaaaagata tatcatttta tcaaggaaca aattgattca gggcaattac
     9481 aggcaggtga ccgcctacca acagaaaagg ccctatcaga gcaattttcg gtgagccgca
     9541 ttacctctaa gcgagcctta gtagagctgg agcaagaggg cttgattaca cgcagcagag
     9601 gtaagggcag ctttgtgacc gatggcccac caccgtctac tcagcctaat aaggacattt
     9661 tgttgatcct gccctttgct tctgattacg aattgggaga ttatgctaaa ggaatcatga
     9721 cggtcgttgc tgacaaaggc tatcgcctga tggtccagct tacaagtacg gtaagcttgg
     9781 aggagctagc tgattatgct ggtgtgattt attatccaga agacgttaat catagtattg
     9841 agctgctctt ttattgtgcc cagcgtgggc ttgctctggt gcttttggat aaggccttag
     9901 acctgtttga ctttccagca gttgttgcag acaataaggg cggagcctat gagttgacca
     9961 agcatttgat tgatcaggat tgccgtcgga tcatgtttgt ggcaactgct tcctttggtg
    10021 aggtttcctc tgttagagat cgttatttgg gttatttggc tgcgatggcg gaaacagagc
    10081 ttgaggccaa ttattttgtg aagctgaagt cagaaagcaa tgctgcttat cttgagcgat
    10141 tggttgatga gctgacggct gctacagctg aaaagactgg tttagtggtt gaaaatgatt
    10201 ggctagccat tcaattgatc caaaaaattc tacaggtcgg gctatctatt cctgatcagg
    10261 tagctgttgt tggctttgac aacagccaag cctctcagtt aatcagccct caattgacaa
    10321 cagctgcaca ggatttttac cagatggggc agcaagcagc gcaactattg atagagcggc
    10381 tgactcggcc tgatcagcag acggcgtctt gtcagcttcc tgttaaggtc tttatcagag
    10441 aaagcagtca aaagtcccta gaaatgctat aaaaaggaga agtgtcatgt ctatttatca
    10501 agccctcaag gactatcagg aggtgataac cagaggtgat tacctcgttt ttgacgcccc
    10561 tgtttcctgt cgctttgttg gtcgtttttt ccgatttgag aaccaaacag ctatgaagcc
    10621 tagtcttaca gcgtcagtct atgtcaactg ggttgaggag ggagcagctg acttgaccct
    10681 taagcacgtt tttaaccgca ccttagctag ggatgccttt accttgacca tttcagagga
    10741 taaggagctt gtgattgaaa gccaaaattt aagaggcttt cgctatgctc aggaggcttt
    10801 agaaaaggta atgactgtta aagagggcag gctttatttg ccgattgttt cggttaggca
    10861 tagtccgtcc tttgccatgc gtggtgtgat tgaaggcttt tatggcaccc cttggacgcg
    10921 tgaggagcgt ttagattgct tgagctttat tgctgataag ggcatgaata cctacatgta
    10981 tgcccctaaa aatgatgact atcagcgcag ccactggcgt gagccctatc cagaggattg
    11041 ggtggctcat tttagggatc tgatccagct tgccaaggaa agacaggttg acttttggta
    11101 catgattagt ccggggcttg attttgacta caccaaggaa gaggactatc agctgctcta
    11161 tcaaaaattg cagcaattgt tggatttggg tgtttgtcat tttggcctgc tgcttgatga
    11221 tattgattac caaatagtgg cagcagttga gagacgtttc aaaaaaacag cctatgccca
    11281 agcacatttg gcaacagctg tttaccagtt tttacagcgg cagcatgcag cccctgactt
    11341 ggttgtctgt ccgacagagt atgataatca tcatgactct ctttatttag cagagttatc
    11401 agaggctatt cctgctgagg tggctttttt ctggactggc ccaagcactc tggccagtca
    11461 gatttctcag gcagatattg agacaatagc agccatctac cggcggccca taatcatctg
    11521 ggataatatc cctgtcaatg attatcagga cgattctaag aggctctttt tgaccccgtt
    11581 tgccaatcgc tctcctttct tgtgtcagcc agactatcag gtcaggggga ttgtgtctaa
    11641 tccaatgatt agctgggaac tatcaaagcc gactttaatt gatatgagtc gctacctgtg
    11701 ggacgccaag cgttatcagc caagctattc ttggctagag gccttgagag actatactgg
    11761 agataaggct atggctttag cgcttttgcg ctttgcttgg cataatggca atcgtcattt
    11821 gcacagggat ctcccctttg aggtggagga ggcccttatg cgtaaggaca tagctagctt
    11881 atctggttgg gtagctgagc tggtagagct ggtggataag ctgaaagagc ttgatattcc
    11941 tgcgtttcaa caggctattg ctccttggtt tgatcgggct aaggctgatc agagcttttg
    12001 gagggttatt ttagagcaag cgcctgatct tgagcagcaa tatgctgagc ttcaggagca
    12061 aaggcatcga attggaagca atattccaag ccgcttttat cagttgcact atcttcagga
    12121 gaatagcatg ctaggcaatc aggcacaggt cgctgaagct agagctgagg attatactta
    12181 attagtttat aagggagaac aagggacatg ctagagtttc cagaaggatt ttggtgggga
    12241 agtgctacat caggccctca aagtgaaggc tgctttcaaa agccgcatcg caatttattt
    12301 gattattggt atgagcaaaa tcctgagctg ttttatgatt atgttggacc tgatacggct
    12361 tctgattttt ttcatcagta tgatcaagac ctagctttat tagcgtcttt gggtcacaat
    12421 tcctatcgga cctctatcca gtggacacgc ttaattgatg attttgagac agccacgatc
    12481 aatcccgatg gactggctta ctataacagg gtgattgatg cctgcctagc acatggtatg
    12541 cgtccggtga tcaatttgca ccattttgat ttgccaattg ctctttatta gaaatatggc
    12601 ggttgggaat caaagcatgt tgtggatttg tttgttgcct ttgctagagt atgctttgag
    12661 cagtttggcg atcgcgttaa ggattggttt gtacacaatg agcccatggt tgtggtggag
    12721 ggctcatacc tgctgcaatt ccactaccct gccattgttg atgggaaaaa agcggtacag
    12781 gtggcttata atctagcact tgcaacggct aaggttatct gtacctacca agaacaagca
    12841 gcagagctga gcaatggcag tgttggtacc attctcaatc tgacaccgat ctatccggca
    12901 actgattcag aggctgatct tgctgctgct catgttgcag agctgtggca caatgacctc
    12961 tttatgtctg ctgctgttta cggtagcttt ccaaaggagc tggtagcaat actacaaaga
    13021 gatggagtgc tctggcagtc cacaccagag gagctggatc ttatggctgc ttatacggtt
    13081 gattacgtgg gcattaattt ttaccgccct aagcgcgtga aggcgccaga ggttattcct
    13141 gtgattagcc cttcctggag tcctgagtgg tattatgatg cctatctgat gccgcagcgt
    13201 cgtatgaatg tggacaaggg ctgggagatt tatccagagg cggtctatga tattgctcta
    13261 aaaatgcgtg atcagtatag gaatatccct tggtttttat ctgaaaatgg ggttgggatt
    13321 tcaggagagg atcgttaccg agatgagagc ggacagattc aagacgacta tcgcattcag
    13381 tttttaaaag agcacctgac ctatcttcat aaggggattc aagcgggctc taattgcttt
    13441 ggctatcatg tttggacacc tattaattgc tggtcttggc taaatgccta taaaaaccgt
    13501 tatggtctgg tagaaaataa tcaccgcact cagcgtcggc gtgtgaaaaa atcagggtat
    13561 tggtttaagg aggtggcaga ggcaaatgga attagctaag aaaagaagaa aaacacaaaa
    13621 gccagcccaa tctcctttaa agctaggttt agagaagcta agagagattt tacaggagca
    13681 gctagtagct ttagcggttt tacctgctag ggtgatgggt tagcataagg gcttgctgat
    13741 gagctatgcc agtgatagcg attaaggaat gtaaaagagg atttcctaac atcataacta
    13801 tccgtctaac gggtgattta ttgtttcgta cctacggagc gaaacggact aaagtcacat
    13861 aactaaaagc atgtcatggc ttgctgtagt acgagtgatg acatgctttt tttagctttt
    13921 aacgggttag ggagtagggc aggtcctcag ccgaatagtg cttgagtggg ggaactagtc
    13981 ccagctgaaa gtcgagctga cagccctgaa tcagatcatc atgattgatg tagagcttgt
    14041 tgtagctagc ctgattgagc ttgacctctt tgacaaattg gtattgaggg acattgcccc
    14101 tacagctgat ttggatagta ttgccatttg gcagataaag ggttgcctga tctacagttg
    14161 gaataccaat caggtattgc ccagttcctg gtgtaacagg gtaaaggcca aggctgttta
    14221 acaggtacca cgcgctcata ctgccattgt cctcatctcc tgggtagcct gtatcggtaa
    14281 aggcatgact gagcagattt ttaaggatta gctgactgta ttgtggctga ccgatatagt
    14341 gatagagata ggggaggtga aagcttggct gatttgagat agcaatctga ccaaaatcct
    14401 gtgcggctag ctcactcatt tcgtggattt caaagccata gctgtgaacg tcaaacacag
    14461 gctcatgatt gcacagctcc tcaagtcttt tggcaatggc ggcgtttcct ccgatcagtc
    14521 gaatgtaacc tagaatatca tgataaaagg caaatccatt ttgataatag gagccctcgg
    14581 tgtagtcctg cccccagtgg atagggttaa agccacattg ccattgccct tgtcgatcct
    14641 tgcttttgag gtagccggta tcagtatcga ccaaatggcg gtaattgagt gatcgcgtgt
    14701 ggtattggtc actaagtgct gtcttgccca gaagggcagc tacctggccg atacaaaaat
    14761 cactataagc ataatcttga gtctgattga cgctttcctg gtagctattt ggcagatagc
    14821 ctagctcttg atagtcttga ttgcccttgc ggccatagcc tgttccttga ctgtctgtat
    14881 tggcagttgc cagcatagcc tctaaaagct caggcatcag gtcttttctg atgcctttga
    14941 cagctccatc agcaataaca gcatcaacca aggttccagg catcaggcct cgctcatctg
    15001 gagacagcca ttttggcaga tagttggtgt cctgataagc tgacaagagt ccctctaaaa
    15061 tatcagcata aatctcaggt gcaattagag acagcaaagg atagacagat ttataagtat
    15121 cccaaaagcc attgttggta tagtattttc cagcaacagg tctttgactt gttgtattat
    15181 agtgaatcgc ctgcccggtt gcagtgattt cataccatct ttggggaaat agcagggctc
    15241 ggtaaaaatg ctggtagtag gccttgacct tatcaaagtc tttatcctta atgtcaatac
    15301 gactgaggta gctgagccac tccttgcggc tgtattcaag gcttttttca aatgatctgg
    15361 ggaaatccct ctgccaattg agctgagctt gatcaaagct aataaaagaa gcagccgccc
    15421 taagctcaag atgtttgagg tcatcagcaa attggagata ggtaaaggac gtcttgctgc
    15481 aatcatcaag agatttggag tttaagtctt ctccgataag cttttttagc acagggctgc
    15541 taaactgaag ataaacaaac atggctaggt ctttatcctg acagtctgtg atgttttgca
    15601 cacagccaag gattgtttta ccatcagctg tcacctgcca ggagcttttt ccggggttat
    15661 ggataatcaa gcctgctttg ccattatcaa aggaaaaatc acaatgaaag ctgtaggcag
    15721 ctgctgttgc tcgcgtcaaa atccgatgtc tctggctaaa aatctcaaga agatgaggcc
    15781 gaaaagctgc ctccttggga cgataggagg tctgattatg aaacacatct cccttggtca
    15841 gcggtccgct gactggaaga aaagtaaccg tcgcaaaatc accgacccaa gggctgggtt
    15901 gatgtgtcaa gcgaatacct gaaaagctgt gatcatcggg gtgaaaccac caagcccctc
    15961 gatcttgact ggtttcgacg cttagataat gcatgccaaa gggaacccct gtcaatggca
    16021 ggcaatttcc ctgtgaaaaa tggtagtgat tggttgttcc aaagcgggtg tcaatgaagt
    16081 ctaatcgatc cacatctcgt cctttctatg ctcttgcata aaatcaatag aggcacctag
    16141 taggttggcc tcgtttttaa agtggcagat agcaagctgc ggtctcaaat cagaaatgct
    16201 gactatctga tagagcttat ccagttcagc ctcaagggca ggaagaagaa agtcagcctg
    16261 agagacaccg ccaccaatta ggatcatttc aggatcaaag gcatgctgga tattaaacac
    16321 ccccattgcc agactttgaa gaaagacctg tctttccttt agggccacag gatctccttg
    16381 atcagctagc tctaagacct ctttaccggt gtaactttta ccatcattta tgatctgact
    16441 atagcgcttg gccatattga ccacagtgcc taattcgctg aaggtttgat aacgctcatt
    16501 catgaccata aagccaaact cacctccaaa taaatgggca ccgtaatgaa tcctgccatt
    16561 aatcactagg ctacctccaa caccggtgcc aagtaccagc atggcaaggc tgctagtgcc
    16621 ttgtcctgca cctagagcag attcggcaag agcagcacag ttggcatcat tttcaatcga
    16681 aaccggcaga cctagtcgct cctcaaggca ttgctgaatg ggaaagccat gaatataagg
    16741 cagtgcactt gctccctcga tgatacctgt tgctttattg acagctccag gggagctaat
    16801 ggcaattcct gagagctttt ctgtgcggta gtaagccagt cgctcgtcaa gcatatggta
    16861 aaagtcctct aggctttggg gagttgggcg actgctttgc ttttttagcc tgcccttgtg
    16921 acaaatagca aatttgatgc tggtgccgcc tatgtcgata cataataagg tcattgtaat
    16981 tcctcctata acaggtatat taccaattag ctacccttag tatgacagat tttgaagtgc
    17041 ttgaaaagac tttctcggca ttcctatatt ttgtgctatg atacctataa tttgtgttat
    17101 caaacctata atttgttgct tgttctatgt gtaagcgctt gatatacttg aagcatcaat
    17161 tgaaaagcaa agggaggttg ggaagatgac gacaaagatc agcagcaaga aatccttttg
    17221 gaaaaatgtg atcaaatacc gcgctttgtt gctgatggta ttaccgggat ttgtctggtt
    17281 catctttttc ttttacattc cagtattagc taatgtagtg gcttttaagg attttcatta
    17341 ctcagcagga ggttttatgg aaagcctgaa agaaagtccc tgggttggct tagataactt
    17401 taaatacctt tttgcctcta aggatgcttg gttgattacg cgaaatacca ttgcttataa
    17461 tcttattttt ttactattta acgtcttttt tgccatcgct ttcgctatta tcatgagtga
    17521 gcttcgaaac aagaaggctg ttaaggtcta tcataccatg tccttactgc cttatttctt
    17581 atcatgggtt gtgattgagt attttgtttc tgccttttta aatacggata agggctttat
    17641 taatcagctg ctcattgata gcggcaatag cccaatcaaa tggtattcca atcccacctg
    17701 gtggcccttg attttacttt tcatgagtgt ttggaaagga cttggctaca acagtatcat
    17761 ttattacgca tcggttaagg gaatatcaga cacctactat gaggcggcta tggttgatgg
    17821 tgccagtaag tggcagcaaa ttagacatat caccattcca cagcttttgc cgatgatgtc
    17881 tatcctattg attattaata ttgggagtat cttcaaatct gactttggct tgttttatgt
    17941 gattcctaaa aattcaggtc ctctttacga tgttaccagt gttttagata cctatgtcta
    18001 caatgccctg acagctactg gtgatattag tatggcttct gcggccagtc tttatcaatc
    18061 tgtggtcgga acctgtatcc tgctcatcac caatgctttt gttcgtcgta tggatcccga
    18121 tgcagcctta ttttaggagg aggacatgga gaaaaagaaa actgttaaaa gggtcaacgt
    18181 cagaaccttt gacccaaaaa ccaatgctgt ctttaatgtg ttaatcgctc tttttgccat
    18241 ctcttgtatc attcctttta tctttgtgat gattatttcc ttcacagatg aaagctatct
    18301 gatcaatcat ggctatagct ttttcccagc tgcttggtcg acaaaggctt atcattatat
    18361 tttccaaggg gctatgtctc atcggatcat aagatcgttt gcggtgtctg tatttatcac
    18421 cgttttagga acctttatca ataccacaat gacctcaacc tatgcttatg ccatctcaag
    18481 accttatttt ccctacaggc gtttttttac catctatgcc ttgatcacca tgctttttgc
    18541 accgggtatg gtagccaatt atttggtggt gagtaacctg ctgcaattaa aggatacggt
    18601 ttgggccttg attttaccga tggctctggg accctttggc attttggtga tgaggacctt
    18661 ctttaaaaag accgttcctg atagtattat tgaatccgct cgtatggacg gcgcaggtga
    18721 attgatgatt tttatgaaaa tcgttttacc tttggcagtt cctgggattg caaccattag
    18781 cctgttctca gccttaacct attggaatga ttggttcaat gcgctgctct atgtgcaaag
    18841 cgagagcctt tacccgatgc aatacctctt gatgaagatt caaagcaata tacaggcact
    18901 agcccaaaat gctggcatga gcgcccagct atctgatagc ttagcctctt taccaaagga
    18961 atctgtccgc atggctattg ttgtcattgc aactttgccg atcgccctaa cctatccttt
    19021 ctttcaaaaa tactttgttg gaggactaac catcggcggg gttaaggaat aatcacccat
    19081 ttggaatagg tcatacagct gaccgttcca atgattctgt tatcaaaaaa agaaattatt
    19141 ttaggaggct tactgatgaa aaagtggcaa acaatcttat gtgtgacggg agctgtgctt
    19201 gcagctgcta gcttgacagc ctgtggaagc aaatcagctt ctaaggacgg tgaggtgaag
    19261 ctattgatgt atcaggtggg agataagcct gataactttg atgagctgat gacaattgca
    19321 aataaacgta ttaaggaaaa aacaggggca acccttgatt tgcaatacat tggctggggt
    19381 gattgggacg acaagatgag gatcattatt gcgtcaggtg aaaattacga cattgccttt
    19441 gccaacaatt atgtggtcaa tgctcaaaag ggtgcctttg ctgatttgac taagctaatg
    19501 ccaaaatacg ccaagaaaac ctataagaac ctagatccgg cctacattaa aggaaatacc
    19561 attgacggta agctttatgc ctttccagta gatgctaacg tctatgctca gcaaatgctg
    19621 tctttcaaca aagaattggt agacaaatat ggccttgaca tttcaaacat caattcctat
    19681 gcagatgctg aaaaggtctt gaaacaattc cacgaaaaag aacctaatac tgctgccttt
    19741 gcgattggtc aagtctttag catgtcaggt gactacgatt acccattgac caaaaatcaa
    19801 ccatttgctg ttaaaatcga tgaaggcaaa ccaaccatca ttaatcagta cgaagatgag
    19861 ccctttaaag caaacctacg cttgatgcat aaatggtata aggaaggctt gattccaaca
    19921 gatgcagcaa ccaacacaga aggctacccg cttgaaggca atacctggtt catgcgtgaa
    19981 gaaacccaag gtcctatgga ctatggcgat accatcttga ccaatgctgc tggtaaagac
    20041 attgtgtcac gaccattgac aaagcctctt aaaacgacct cacaagccca aatggctaac
    20101 tttgtcgtgt caaatgtgtc taaaaataaa gaaaaggccg ttgaagttct ttcccttctt
    20161 aacagcgacc cagaattgct aaatggtctt gtttatggtg ttgaaggcaa ggcctgggaa
    20221 aaggttggcg acaagaaaat caagctgctt gatggctacc aacccaaaat gcacatgggt
    20281 gcttggaaca ctggtaacaa caagatcctc tacacccaag aatcgatcac agatgatatg
    20341 attgcaaagc gtgaccaatc aatcaaagac gctaaagagt ctccgatcct aggctttacg
    20401 gtagatacca aggcaatcaa aacggagcta tcaaaaatct caaacgtgat gaaccgttat
    20461 aaagctagta tcaatactgg tacagtagac cctgatgaag ctcttccaaa acttctttca
    20521 gaccttaagg acgctggttg ggacaaggtt caaaaggaag tgcaaaagca attggacgac
    20581 tttgttacaa aaaataaata aggcaatgga ctttccttgc aaggtggtaa gaactgggga
    20641 cagcctcagt tctttttagc tcaagcaggc atacaagagc tgacagataa ggcctctctt
    20701 agaaaaaagc cagagcctgc ttgcaaggca gttggtccac caaagccctt gctgacaagg
    20761 ttttaccagc cttagtcggc tgtcctcttt ttattaagct tttgtcacaa ttagagtaaa
    20821 atatgctata ttagaagtat ctcatcttat catcatgaca gctaagacct tagtcatctg
    20881 gctgagggat cgttgcttct cttagggcgc tattggtcct acaaaggata ctagaaaagg
    20941 ataatcttat gacaggaatt gaaaaagcct gctttctcat ctggaaaatg atgcagctaa
    21001 cccttatatt tcatttgctt tccttatgtg gtgctgtgat ttttggagtg gggccagctt
    21061 ggcagaccat tgttaccttg tttttggaga ccagtcagca ggagaaacat tattcgctca
    21121 agcgggcctt tcagatatgg cgtcgggtct tcaaagaggc caatctcagc tttttcttct
    21181 ttggattatt gctattattg ctgaatacga gcctgtactt ggccattcaa tttcaatcgc
    21241 tgctgtggtt tagcctatcc tttattatca tgtttgtcat ggtttggctg gtgatgattg
    21301 tgatttacat gaccttttat gcagtgacct atgaaattgc tttttgggag aatctcaagc
    21361 tgtcttttat cagtattttc ttgaatgcca ggcagttttt gttgaccctt gtggttttag
    21421 ctggagttgc ttggtttact tggcagtata agggcttgta tctttttctg agctttggtg
    21481 cgctggtttt gttgctggat atggtcacca agcctaatcg tcgcatggta gatggagtca
    21541 ttgatgacaa gtaaatcttt aaagcggttc ttgatggagc atattaagca gggcttttta
    21601 attaaccgct tgatgaaaat atatagcctg tttatcgtgg ctctctttag cttaagtgcg
    21661 gttggtctaa gcacctattc gattcgaaat acctaccaaa tggttgacaa tcaaatgcaa
    21721 atgcggctag atgagaccct agcaaggcta caatctcaaa actatattac cctgcgcgtg
    21781 ctggagcagc tgatcgggcg tccagaggat tatcgaaatc tgtatcagta catgatattg
    21841 acccctaatc aatatcttac taaggttttt gaggattggg gtgagggcaa aaacacacct
    21901 ctgttttcag agcaggtcag aaggcttttt gatttgtatc cagatttaga tgggctgacc
    21961 ctgatgctgg acgatagcac gtcctatttg tatgcagata ggtcgattaa gaccggccgg
    22021 ctcttatttg gtaagcctca gacgctaaag ggcaattact tagtaaggtc cattcgccac
    22081 cctgagtcag gtgatgttac aggccgcctc tatctgcact ttgcaagccc cagcacgatg
    22141 ctacagcctg agcagcataa gtatctagcg acctttgcct ttgattacta tggcagagag
    22201 ctctttcatc agggaggcgc tgcctttccg gagcttgaag caggtcttaa aaaggcgcta
    22261 aaggcggatc aggctattga tttgacagct ctcagcaaga gctatcatat tcagtacaat
    22321 cgctcgggag acttgctggc ctatgtggcg gtcaaaaggt cttattttat ggaagaggct
    22381 gtgcgtacaa tgctcctgta tggccttggc tcgttattgc tagcttggtt attgctacag
    22441 ctccttttca gggtatttcg caattatatc cgacaggtct ctgagattac agatactatt
    22501 gaaatggttg cagctggtga tttgtcgtta aggattgaca acagtcatat ggaattagag
    22561 ctgtatcaca tttctgaggc gatcaatcaa atgcttggca acatcaatgc ctacatttta
    22621 gaaatctatg tccttgaggt tgagcaaaga gatgcccaga tgcgtgcctt gtcatcacaa
    22681 atcaatcctc attttttgta taacacccta gaatatattc gcatgtatgc gcttagctgt
    22741 cagcaggagg aattggcaga tgtgatttat gcctttgccg ctttacttcg aaataacatc
    22801 agccaggata aggtaaccac tctaaaagaa gagctggctt tttgtgaaaa gtacatctat
    22861 ctgtatcaaa tgcgctatcc agatagcttt gcctaccatg tcaagcttga tcctgtcgtg
    22921 gctgatgtgg aaattcctaa gtttatcatt cagcccttgg tggaaaatta ttttgtgcat
    22981 gggattgatt acagccgcta tgataacgcc cttagcatca aggcgctaga tgaggaggac
    23041 agtattttga ttcaggtgct tgataatggc aagggtatta gccctgagcg cttagtggct
    23101 attgaaaagg gcttagagga gccgcaatcg acggggaata gctctattgg gctgcaaaat
    23161 gtctatatgc gcctatttca caaatatcga gacagagtga cttggtccat gtctcaggca
    23221 ccgactggtg gctttaggat tcagatcaga attagaaagg aagcttaatg tacaaggtct
    23281 tattagttga tgacgaatac atgattttac agggcctaaa ggtgattatt gactggcagg
    23341 cgcttggctt tgaggttgtg gcaacggcaa ggtcagccaa agaagcctta gcttacctag
    23401 atgactgcgc tgtagatgtc atgatttcag atgtcaatat gcctggtatg acaggcctgg
    23461 aattgattga ggcagcaaga gatgtattgc cgcatttgca gaccttgatt ttatcaggct
    23521 atcaggaatt ttcctatgtg caaagggcta tggagctaga gactaagggc tacctcctaa
    23581 agccagttga taaaaaagag ctggtagcta aaatgctcta ttttaaggaa tggcttgatg
    23641 agcagagggc agcttctttg cgtcaggctg cttatcgtga gggcttgata aatctctggc
    23701 ttgctgatga attgagtgag aaagagtttt ttcaactaac gcaggagcaa cccgaggctg
    23761 agcttttagg ctttacggtg ttgtatgtgg attgcaagac ttttagccct gccttagaag
    23821 ccttttttga ggcctccaag cagccctttt acttaaaaaa ggcagagcaa aagaaggtct
    23881 atctagtcat tctattagga cagagccatc aggctaagcg ctttactaat acgcttcagg
    23941 agcgatttta caataccatc aatcagatca ttctaggaga aacggttgtt gattgggaaa
    24001 atgtgtatga aagctataat caggtcagaa ggagcttttt ttacaacagc gaggtgtctc
    24061 aggtagctgc taagaccaac gctaaaattg agctgccgga atcgcgattg cagttttttt
    24121 cctttaacaa gaccttgatg attggggacg agccaactat tgtctccaaa ttacaggcaa
    24181 tctttgagga gatgacagag ctaagcttct ctcctgagga cgtcaagcac gtctcttttc
    24241 tcttattttc agacatttat cgccaatttc cgattttaga tcgaacgacc tacctatcga
    24301 tggtcaagac tattcacgat agtcagtcca ttgatcagat cttatcagcc ttaaaaaagg
    24361 tgcttgagct gacaagcaaa agcaatcagc cccaaaagcg ctattctgat ctggtcagtg
    24421 aagccattac ctgtattcag gaggaatact ctcaggaatt aaccctcaag gctgtgtcag
    24481 atcgcttgca tatcaatggg gtttatttgg gacaacgctt taaaaatgaa acagagtgta
    24541 gtttttccca atacctcaat caggtgagga tccaaaaggc acagcaattg ctgctttaca
    24601 ccaataaatc gattaacgaa attgcctatg agacaggcta taatactaac cattatttca
    24661 taaaaatgtt caaaaaatta aatggtttat cgcccaagga gtttagagac cgttataaag
    24721 ataattatca agctataaaa ggaagctatt aagaaagggg gcgctatgtc tgtagagaca
    24781 atcactggtt caacggatca atctcatggg gatatctatc agcttcactg gattgataaa
    24841 gtagggcgct gccatgcctt ttcaaagggg tggcgctttc tgatggctga tttgcagctc
    24901 gctcaggagc cattttttga tgattcggac tggcagcaga tagctttacc acatgatttt
    24961 agcattaatc agccctatac ggttaatggc gaagctcaaa gtgcctataa gctaggtggt
    25021 gtaggctggt accggaagta ttttgccctt gatccaaagc tggctgacca taaggtctat
    25081 gtgacctttg atggggctta tatggaaacg caggtatacc ttaatgggca tttgatagga
    25141 gagcatgtca atggctatca ggcctttagc tatgatctct cagcctttgt aatccctggg
    25201 caagagaatc tattagcggt tcgggttgaa catctggtgc ctagctcgcg ttggtattct
    25261 ggaagtgggc tttatcggga ggcttttttg accgttcttc cgaaggttca tcttgataag
    25321 gatcggcttc gtttatcctt atcccaggca gcgcttgagg ctgatagcca agcgcttgag
    25381 atagagcttg gactcagcca acaggtcccc ttgagtggct atcagcttag ccttagtctg
    25441 tttgagcagc tggcagatat ccagcagaga cagacagtat atgagagtaa accggtagcc
    25501 ttggacctct tggaggagtc aggtaggctg gtgatgacca ttcctcttag gcatatcaaa
    25561 ctgtggtcgc cagctcagcc ccagctctat cagcttgata tgcttcttta ccataaggga
    25621 gcagtgcttg atcggctgac acttgaaaca ggctttcgac agctgcattt tgatgctgag
    25681 tgtggtttct ttttgaatgg caaagccttt aagctgcaag gggtctgtct tcatcatgat
    25741 cagggtagcc tgggggcatg tgcttatgag gaagctatag ctaggcagct tgttttgcta
    25801 aaggaaatgg gagcaaatac ggttcgtgtc acgcacaacc ctagtgccag aaggcttaag
    25861 gatctggcta acaggcttgg gttatttctc attgaggaag cctttgatac ctggacttat
    25921 gctaaaaacg gtaatagcca tgatttttca agccattttc acaagacagt gggacaccaa
    25981 aatgcagcca ggctaaaggg agtcactaca gcagaaacca cctgggcgca atatagcata
    26041 caggccatgg ttctctcagg tcttcatgat ccatctgtct tgatgtggtc aatcggcaat
    26101 gaattgttag aaggcttctc agctgatgtg agccactacc cttatgttgc taaggagcta
    26161 tgccagtgga tcactgagct ggatcagtca agacctatta cccttgggga taataagctc
    26221 aaggacaagc attttcattg ggcgcaggaa acaaaagcgt tggcagagca ggtcaatcag
    26281 ctccagtccg tgcaaggagt gattggactt aactatgcta aggccagaga ttatgatcga
    26341 ttgcataggg acaacccgac ttggctgctt tatggctcag agacagcctc tgctattaat
    26401 agtagagggg tctatcatct caagggagga gctagtcagg atcatgagct aacctcctat
    26461 gaccagtcaa cggttgactg gggatcctta gctagtgagg cttggtatga tacaatcaca
    26521 agggattttg ttgcaggtga gtgtgtttgg acgggctttg attatctagg ggagcctact
    26581 ccttggaaca agattgactc aggcgcagct gatcagtggc cgtcgcccaa gcaatcctac
    26641 tttggtattt tagatactgc tggatttgct aaggatagct attatttcta ccaaagccaa
    26701 tggtcaaaag acaaaacgac acttcatatc ctgcccagct ggcaggaaaa agaccttcag
    26761 ctagatgatc agggcatggt ggaggttgtg gtttatagta atgctgctag tgtgagaata
    26821 ctttttgatg atggtcatgg gggccagatt gattatggca tcaagaccct gacaaggcat
    26881 gaaacaccag caggccattg ctaccagcta tatgagggtg acgatgcagc agaattacct
    26941 catcaaaacc tttacctgac atggaagctt ccttatcgct caggcagctt gagagctatt
    27001 gcttatgacg acaagggaca ggtgctcaca cagaccagcg gtcgttcctg tgtgagcagc
    27061 taccagcagc ctgctcagct ttcctggtcc tgctttgagc ctcctaaact gcttgcagag
    27121 cctgcgctac tttatcttga attgtctttg ttagatgcta atgagacctt ggtgctcagt
    27181 gctaatcctg tgattaagct tgaggttgag ggtcctggag cctgccttgc tctggataat
    27241 ggcgatcctc gtgaccatag gccctatact gccttgtcac gccgagcata tggtggcaag
    27301 ctattagcca ttattgctct tgatggtcgt gcgggtcagc ttagaataac agctagagcc
    27361 gcaggattcg tggaagccag ctatcagttg acggtttctg aagcagccgt taatgagaag
    27421 cttttagcct atcagcttga taaatacagc tttatcacta atgagacaaa taagcctagc
    27481 aagccctatg caaggtcaag aggatcagct gttgatagct taatgcctaa tcctgatagc
    27541 tgcttaaagc ggcaaggcca ttatctgcct gataattctg taatggtttt tagctataca
    27601 acagcattat caaggccact gacctttcag ccactgatca aaaggctgct aaagggcaat
    27661 gatatcattc taccagactg gctgcagcct agggcagctg ctggccagtt atttaccaag
    27721 gcttttccta ttgattggca gctaacagag gcagtttttt ctgaggagtc aagggttagt
    27781 gggcagaccc tttgttttgg agaggctttg gagcttgaag ctatccttaa gtcagataca
    27841 aaaggattaa ggatcaatca agagcttagc ttagttgcta aaaagaagcg gctgtttcag
    27901 agtgataccc agcttagcta ccgctatcaa tacgatacca tacaggccat tggtgccatt
    27961 agcctgacag gactaaagaa gcccttaagc tcgcttaggc ttgttttgga ctatcgcagc
    28021 agcaccaatg cgccatcaaa acagctgatc ctatcgcttg atcagataga acagccctgt
    28081 cactacatca tgctggaaga agtagttgat gtgctaagcc tggacctaac attagagcag
    28141 ccgatcagac aggcttttga cttagctagg cttcagctag gcctttggag catggttgag
    28201 gaggcttagg cttcaagctt atcggctcat actgtcaata ggattgagct gagacagtct
    28261 ttgaaaaata aggtataatg acagtaaatg cctagcaagc tttgctaggt tagcaaaaaa
    28321 taagcatcgc ctgatatgat gtaaaggagg aggtatttga tgctagagcg tttatcaggt
    28381 cagacacgat taacagcttt gctggcagca ccggcacgtc acagcctatc accgaaaatg
    28441 cacaatgcag cttatgctaa gctggggctg gattatgcct acctagcctt tgaggttggt
    28501 aatgctgagc tagctgctgc tgttcagggc atgcgtgcct tgggtatttg cggtgcaaat
    28561 gtgtccatgc caaataagca ggccattgtc ccattgcttg atgagctatc accggctgca
    28621 gccttagctg gagctgttaa tacggttgtt aataaagatg gcagaggtca tcttgttggt
    28681 catatcaccg atggcacagg tgctattcga gccttagcag aagaaggggt ctcgataaag
    28741 gatcagatca ttacgattgc cggtgcaggc ggtgcaggca cagccattgc tgttcaactg
    28801 ggacttgatg gcgccaagga gattcgacta tttaatcgga aaacagctac ctttaagcag
    28861 gccaagcagc tggttgctag aattaatacc caaacctcag ccctggcaag ccttcaggat
    28921 ttagcggatg atcgagcctt taggcggtct atttcagagt ctagcattta tattgacgcg
    28981 actggtgtag gcatgaagcc ttttgaggag catcgcctga ttactgatcc agctcttatt
    29041 cgcccagatc ttgtggtttt tgaccttgtt tatcacccgg cagaaacaaa gctcttagcc
    29101 tttgcgcgtg agcatggggc taaaaaagtg atgaatggcc taggcatgct cctttaccaa
    29161 ggagcagaag cctttaagct gatgacaggt gaagacatgc cggtagccta tatccgagag
    29221 cttttatgtc agaacaagga atgaacgcct gctgctcacg ccggtatagg aaaaagaaaa
    29281 aaaggttaat tgctcagctc tttgattggt cttgaggttt gtcggcattt tatttataat
    29341 aaaaagcacc aaaagcaaag gagcagccta tgatattgac acaatttgac cctgactacc
    29401 aagctatcat taaccctaag gaccttgtag cagaaataga tgactttcct aaaacagtag
    29461 tcacctgctt tgcaagagca acctttaata gggtacttaa tgcactgcca catcgactga
    29521 tagccacaac aagcgttgct aatcttgata ttccaatata cgaattagat gttaaagggc
    29581 ataagcttgg ctttttcaat tcctacgttg gagcagctgg ctgcgttggg gttttagagg
    29641 atatcattgc tatgggaatg aagcagctct tggtttttgg gacctgtgga gtcttagacg
    29701 ctactatcag tgaaaactct attattattc caactagtgc tattcgagac gaagggacca
    29761 gctaccacta tcagcctgct agtcatgaca ttgcagtgaa tcaagcttat ttaacaaggg
    29821 ctattgatgt tttagaacag cattcccaga cctataccct tggtaagacc tggacaacag
    29881 atggcattta tagagaaacc agagacaaga tgattcaacg aaagcaggaa ggggctattt
    29941 gtgttgacat ggaatgctct gcgattgctg ccctagcagc tttcagacag ctagagcatt
    30001 ttcagttttt ttattccgct gataatctag atgctgatga atgggacgca agaagcttag
    30061 ccaatgaagc agacctagaa gccaaggata acattgcctt tattgcctta gagttggcct
    30121 tacgattatt taaggataat taaaaaagca ccaagagcta tgaagtgcct ccaaaaggtt
    30181 agattaaggc tctaacgcct gggagatcag ttcagctcaa ggtgcttttt aggtgtcatg
    30241 cagacagctc acctctgcat gtcaatataa tgtttagagt agcctatgct tcttatacct
    30301 atgccttagc attcacctag ggacaaagca atgaagctta ggcctttcac cttactgtga
    30361 aaaaagtggt cttttctcat caaaagactc agtaaacaag aggctttgaa gcctttttgt
    30421 ttttcagaag cagcagtttt ttcactcgac taataagaca ggagaaaagc cttctcaggc
    30481 gatatctagc aggcttctta gccaatccag caggcgactg tcatgcttag caataggaaa
    30541 gcttacatag ccttttgtcg ttggcaaaat gaggacaata tgctgaccag aatttttctt
    30601 atctgttttt aaaacagtca tcaaggcttc ggctgtcatt gacttagcct caagtgtggt
    30661 aggtagctga taagcctcaa aggcagcctg taatgcctct aaatcctgtt ggctcaatag
    30721 ctgctgctgg acggccagct tggcctcaaa gaccatgcca atcgcaatag cctcaccatg
    30781 cctgtaaagc tcgtgatggc ataaggcttc aatcgcatgc cctagcgtat gcccgaaatt
    30841 taaggacatg cggagattgc cttcaaattc atccttttca accactcttt ttttatggca
    30901 aatcgcttga aaaatcattt gcctgagctg ctcttgattg cggtccttgg ggaaggctag
    30961 gagctgttga aagagcttgc gatcatgaat aaaaccaatt ttaatcattt cgctgatgcc
    31021 gcaggcaaat tctctttcag aaagcgtgtc taaaaacttg gctgacacga taatctggtt
    31081 tggagggtag atactgccta tcatattggt caagccctta aagtgaaccc caaccttacc
    31141 accaatgctg ctgtctacct gactaagtaa ggttgttgga atctgaacgt aggaaatccc
    31201 gcggtaaaag gttgccgcaa caaatccccc aagatctcca atcacccctc ctccaacagt
    31261 aacaatgacg tcctttttag aaaaattagc cctaatcagt cgatcgtaaa tccgactaac
    31321 ctcctctaga gacttagatt gcccccctgg agcagcaata tgaaggtaac tatcgtaatc
    31381 ctgttgaaaa cgtctaaata aaggctggta taaatcaaat accgtttgat cagtgataaa
    31441 taatagcttg acgtctcctt tttcagcaag aaattgattc agcggctgaa aaatatcgtc
    31501 tgtaaagata atcggatagt cattgatacg agacttaacc tgaagtgttt gtgtcatgcg
    31561 tctttctctc ctaagcacca ttagttcaaa tgactggacc tgtggctgct gttagttagc
    31621 tttcccaaag ctcttttcca agctgctcta gctgttgata atcaatctgc tgcgcggcat
    31681 ctgacaaggc aagatcaggt gtagggtgca cctccatcat aataccattg gcaccgatag
    31741 ccttagcggc cttagccgca ggcaatagta aatctcttct tcctgttgag tgagagacat
    31801 caacaatgat tggcagcttc accttttgct gaataatagg gactgccatg atgtctagca
    31861 tatttctagt ttccacatca tagccacgaa ccccacgctc gcataaaata atattttgct
    31921 tgccattttc ttgtaaataa gataaagcac ccaaatattc ctcaatggtt gccattagtc
    31981 ctcgtttaaa caagataggc ttgtcaatct ttgacaatac ctttaacagt tcaaaatttt
    32041 gcatatttcg agcgccaatc tgaataatat ctaaatagtc ataggcttcc tctagctgcc
    32101 tttcagacat aatctcacta acagccttca gcgaaaattc ctggcaaacc tcatgtagat
    32161 aggtaacccc tgtcagccct aagccctgaa aggagttaga agaggttcta ggcttatagg
    32221 ctccccctcg aaaatacctg tagcctaaag ccttggcact tgctgctgcc tgtctgattt
    32281 gctgataaga ttcaatggca cagggaccaa caataaagtt actcttttga cagcccttgt
    32341 ttaaaaaatc agctattata tcgtttccca tttatactct ttcctaatat gatattgaga
    32401 gaatgattcc ccaaaggtaa gatgacagct ctgtcttaga taatactgtg aataaggcat
    32461 gacagaacta ttcatagctt gggaaatcat accataatca agcttaaatt tcaagctaat
    32521 aaagagagtg accagctcgt tgacaaagga gaagcttttg agaatcctag ccctctaagg
    32581 tagagatttt atggctatta gagctgttga gaatgcttat tagctggaat aggcaagcat
    32641 ggtggggaag tgctgatgat tgagtatcat gatgaggcta gttatagctt ttattgtggg
    32701 agagtttagc ttttcaaata caaaaagaaa aggtttacct atatcgtttt tttggtgtat
    32761 atataatata tagaaagcaa actattttag aaacagaggt aatggtagat gttaaggtat
    32821 ttaaaagcga ttttatatct attggctccc agattagctt tttcagtaac aggtgtatta
    32881 tttcctgatg tttttgataa tttattcttg gtttataata ttttaatgac acttgctttt
    32941 tggcttgcga tttattctgt tgacctccca gaaaaatagt tgcgggactt gtttagtagt
    33001 tggttaacaa agggtagatg atcagttaaa ggtgaagcgt ctgagctatg ttggccatta
    33061 tgcgtacagc tggcaaaatg cttttgatcc aatcggttaa acctcaagct attctctttg
    33121 ggataacaaa taccccatct gtctcagaca aagaatggca acgcctaaat aggattaaca
    33181 tctgcaagtg ctcttgggac tgccaatgct cttagtagca taggtgattt ttcagcgcta
    33241 gagacttttc agcagatgag aaatagtcgc aataaacgaa gacaaaaaga cttggcttga
    33301 gctcgtattt ggccttaaaa tagtagtcag tcgagcttaa aaaaaagtca ttgcagctta
    33361 tgaaggttat cgtatcctta tttcaactga gctaggtaag ctagggagtt tcctttaggt
    33421 gtaacgatag aagcgatcaa ataattactt catttaaaga taaggattgt aataagcata
    33481 gaaaagagca gttacttgac ataactactc aatgtaaaac cgtttcaggc ggtggctttt
    33541 gttattagat aaaaaataat cgtcatcatt cggccaaagt tagaacggtt atgttttatg
    33601 ctcatctttg aagatgttat agcacaagcc aatagggaga ctaaagctta aaaagagttt
    33661 gagtagcttc aaaggctgct agctttttgg cctcctccat tttgttagct gttgatgaat
    33721 cgcccatagg caccaccacc cactcagaac gagcagccac ctgtcttaat ttttttactc
    33781 taccactgta gcatgccaca agaaaaaatc agaacactaa tgacatttaa aaaaaaaaaa
    33841 aaaagacttg cacaccaaaa caagttatag tatcatagaa aggtagccgc tatagttaaa
    33901 tggtataata aagcaatggt aatgcttcgt tccgagttcg attctcggtg gtggcatctg
    33961 agtactgtcc taagtcttat taggacggtt tttttattgc taggtgaacc aatagtagtc
    34021 atctgtgaat cattaccata gtggcttctg ttcgcccaag catagcaaag ctgctgtcag
    34081 aatgaaccca gccaacaatg tcaatagaag cagcaccaga caagccttta gtcacccatg
    34141 ctttaaagat tttacggctg taatgttagt aactgttacc tgttttgttc aagttgtctg
    34201 tgacatcaaa tcacttgatg ctaccagtac tgtcaataca ttagctgtca cttggcagtt
    34261 gttctgacta ctactaaaaa tagcagctat cagcgttgca atcaaaaaag aatgcgaatc
    34321 aagctctcct gatcagctta actttttgaa agagtttgta cgggtcaagc atcagcaagt
    34381 cagactgcct tatttgtttt tatcataagc ttctaagaaa atagcacaat aagccaggct
    34441 gtggtataat ggtaaggatt aagtcagaaa gaggggggca gacatgtctt atgagcaaga
    34501 ctttttgaga gattttgaag actgggtgaa ggctcaaatt caggtcaacc agctagctat
    34561 ggcaacgagc cggcaaattg caaaggaaga taatgatcaa agagccagag atgcctttat
    34621 tcgttatgag agtaagctag atgcttatga gtttttatta ggaaaatttg ataattataa
    34681 taaaggtaaa gcttttcatg aggtgccaga cagcctattt ggtagccgtc attattagag
    34741 gaagggataa gcagtaatca tggcaagacg atacaatcgt aaaaaacaat acaagctaca
    34801 gcttaagcgt caaggactgc tcaaggcagt aatcaatcaa gtggagcaga ctgtggaaaa
    34861 ggtggttgat aagactaaag aagcagtgca taccgcttca caaatggtaa cagcatcaaa
    34921 gacagagact gctgatctac aggataagca gagcattgct gaaaaagcag ctcagcctaa
    34981 agcagatgta gcttctagta gcttggctga cagttctgag gtttcaagtg aaaaagaggc
    35041 ctcaaaggct agcagtgaag tcttatcacg cgatgctttt gcagagttgg ctgaggtttc
    35101 agagcttcgg gcagatattg ttacggtgct ttttgaggct ggtattaggt cagctgctgc
    35161 ttttagccaa tggacagagg cagagctttt ggcgcttaag ggaattggac cagcgactat
    35221 cagcaagcta aaggaaaatg gtgtcaactt taaaaagtag tctgattttt attgcttaat
    35281 aagtataaat ttgttagaat gttagcaatc agaggtatct tgagtttgtc tgttacagag
    35341 agcggtggtg ttgagaaatc cgcacagatg tcaagttatg tagctgaggc ttacaatgga
    35401 aaaatgataa agcagcagat taagtgtaat ctgaaacagt ggtggtaccg cggattatta
    35461 gtgaattcgt ccctgtctag tcgattgact aggcggggtt attttttgga ggacttgcta
    35521 tgattgagat aatgggttct gttgagaata atagattacc agatgtcaaa actagtcgtt
    35581 tgctgctgcg gcagcgtact ttagctgatg ttgaagcgat ttttgcttat gctagccgac
    35641 ctgaggttag ttacccagca ggctttccac ctgtgaaaac ccttgaagaa gaggagcatt
    35701 acatcgcaaa cacgatgcct aagcgctggc ttttgcaaca gctgccggca ggctatggca
    35761 ttgccctaaa gggtgacaat aggattattg ggtctgttga ttttaacaac cgtcacgcag
    35821 atgatgtctt tgaaatgggc tatctgctcc accctgatta ttggcatcag gggattatga
    35881 ctgaggcagc gagtgccctg ctagaggttg cctttactct gcttaagctt cataaggttg
    35941 aaatcagctg ttacgattac aatatgggga gtcgtcggat cgcagaaaag ctagacttca
    36001 ctcttgaggc gaccattcgt gatcgcaagg acgctaaagg caatcgctgc gcagacttgc
    36061 gctatggact gttgaaaaga gaatgggaga ggcagtgtag ataaggagta gactctctaa
    36121 aatatgcgtt aatctgtcaa aagcatttca taagaagtcc tcaaactcaa agcgcttatg
    36181 actaccaaaa ctggttagcg cttcgccaac cagtgtcatc agtttctggt agtctgcctt
    36241 gagcagcaag tgttatgtta agtgaggtga gaagaggtaa gagagatcgg aaagaggttt
    36301 ggtatgaata ttatcttaat tggagcacag gcgtctggta agatgacaat tggacaggaa
    36361 ttagaaaaac tgactgacct gactttattt cataatcatg aatcgattga ttttgtgact
    36421 aagtttatac caatgtcatc ggaagctaga gaactaattg atgagctacg attgctattt
    36481 tttaaaacat ttgcaaaacg tcagcaatca attattttta ctgttgtcat tgattttaat
    36541 gcacctgaag atatagcgtt tttggaaaca ctacagagtg tgtttcatga tttcgacaga
    36601 gaggttttat tcgttgaatt agaaatagat ttaaaagaac gcttaaggcg aaataaaact
    36661 gaaaatcgac tttaccacaa accgataaag cgtcatttgg agtggtctga gaaagatatt
    36721 ttggatactg ctaaatttgc taactttaac cctgcaaagg taccagaaaa tcttaaatat
    36781 tattgtaaaa tcaataatac gagtctttct gctcaagaaa cagcgcagtt tatcgtccaa
    36841 aaaatgaaag agttagaagt aagctagaaa ggacaccata tgtcaaaaga actttcaccc
    36901 aaatacaatc cagctgaggt tgaggctggg cgttatcaag cttggctgga ccaagatgtt
    36961 ttcaagccat caggcgacaa gaaggctaag ccgtatgcta tcgtgattcc accgccaaac
    37021 gttacaggga agctgcacct tggtcatgct tgggacacga cccttcaaga tattattatt
    37081 cgtcaaaagc gcatgcaggg ctttgatact ctctggttgc ctggtatgga tcatgcaggt
    37141 atcgccactc aggctaaggt cgaggagcgc ttgcgcgagc aggggatttc ccgttacgat
    37201 ctcggtcgtg acaagttctt agacaaggtt tgggaatgga aggacgagta tgcagcaacc
    37261 atcaaggagc agtggggtaa gcttgggctt tcactagact atgcgcgaga tcgcttcact
    37321 cttgatgagg ggctctcaaa ggctgttcgc aaggtttttg ttgagcttta caagaaaggc
    37381 tggatttacc gcggtgagtt catcatcaac tgggactcgg cagctaggac agctctttca
    37441 gatatcgagg ttatccataa ggacgttgag ggtgccttct accacatgaa ctatatgcta
    37501 gaagatggtt cgcgcgccct tcaagtagca accacacgtc ctgaaaccat gtttggagat
    37561 gtggctgtcg ctgtcaatcc agaagatcct cgttacaagg acttgattgg tcaacatgtt
    37621 gttctgccaa tcgtgaataa gctgatccca atcgttggag acgagcatgc ggatccggca
    37681 ttcggaacag gggttgttaa aatcacacca gcccatgacc cgaacgactt tgaggttggt
    37741 gggcgtcata atctcccaca ggttaatgtc atgaatgatg atggtaccat gaatgagctt
    37801 gcaggtgaat ttgcaggtat ggatcgattt gaagctcgta aggctgttgt ggctaagcta
    37861 gaagaaatcg gtgcccttgt tgagattgaa aagcgtgttc attcagtagg tcattcagag
    37921 cgtacaggtg ttgtggttga gcctcgcttg tcaacacagt ggttcgtgaa gatggaccaa
    37981 ttggctaaaa atgctattgc caaccaagac acagatgaca aggttgactt ctacccacca
    38041 cgcttcaacg ataccttctt gcaatggatg gaaaatgtcc acgactgggt aatctctcgt
    38101 cagctttggt ggggacatca gatccctgca tggtacaacg aagcaggtga catgtatgtt
    38161 ggtgaggaag cgccagcagg tgatggctgg aagcaggacg aggatgtcct tgacacctgg
    38221 ttcagctctg cgctttggcc attttcaact atgggctggc ctgatgtaga ctcagaagat
    38281 ttccaacgtt acttcccaac gtcaacattg gtaacaggtt acgacatcat cttcttctgg
    38341 gtgtctcgta tgattttcca atcgcttgaa tttactgggc gtaagccttt ctctaacgtt
    38401 cttattcatg gtctgattcg tgacgaagag ggacgcaaga tgtctaagtc gcttggaaat
    38461 ggcattgatc caatggacgt tatcgaaaaa tatggtgcag atagcctacg ctggttccta
    38521 tcaaatggct cagcccctgg tcaggacgtg cgcttctcct atgaaaaaat ggatgcgtcc
    38581 tggaatttca ttaacaagat ttggaacatt tcacgttaca ttctcatgaa taatgagggc
    38641 ttgacacttg agcaagcaag tgcaaatgtt gagcaagttg cgtctggcgc tgctggaaac
    38701 gtgacagact gttggatcct ccacaatctc aatgaaacaa tcggtaaggt cacagagaac
    38761 tttgataagt ttgagttcgg tgtggcaggt catatcctct acaattttat ctgggaagaa
    38821 tttgccaact ggtatgtgga gctgaccaag gaggttctgt acagcgacaa cgaagacgag
    38881 aaggttatca ctcgctctgt tctcctctac acgctggata aaatcctgcg tctccttcac
    38941 ccaatcatgc cgtttgtgac ggaagaaatc tttggtcaat acgctgaagg ttctatcgtg
    39001 acagcggact atccaacggt tgatcctgct tttgaaaatg aagctgcgca caaaggcgtg
    39061 gaaagtttga aggacttgat tcgtacggtg cgaaatgcgc gtgcggaggt taatgtagca
    39121 ccaagtaaac caatcactat ccttgtcaaa acaagcgata gcgacctgga agccttcttc
    39181 aacagcaatg tcaactacat caaacgcttc acaaatccag agaggcttaa gattgcttca
    39241 agcattgtga ctcctgagtt ggccatgtcg gctgttatta caggtgcaga aatcttcctt
    39301 cccctagctg atctgctcaa tgtcacagaa gaattagctc gccttgaaaa agaattagct
    39361 aagtggcaaa aagagcttga cctggtcagt aaaaagctca gcaatgaacg cttcgttgct
    39421 aatgccaagc cagaagtcgt tcaaaaagaa cgcgacaaac aggctgatta ccaagctaaa
    39481 tacgatgcaa ccgtagagcg catcaaggaa atggagaagt tagtaaggta ggatagtgat
    39541 catctaagag ccaattggct ctttttttga tatactgtca aggagtaatc atcacaatta
    39601 tctatataag tcaaaggagt gtctcatgaa aaaaagagtc attggttggt taggtgtgct
    39661 ggtaataggg cttatgcttg gtctgatatg gtggaaatgg ttagtggcag atcggccact
    39721 aacccaagca ggtcaaggaa gtcatgacca cagcagcgac aaaggcctca gtgccgcata
    39781 aggaaaaaat ggaatcaaaa gagcctgaga catcacatca gccagaagcc tatcctgatc
    39841 ttgctagcta tcaggaattg gctgttcatg tgtcgattgc agaccaagtc atgaccatta
    39901 taggagatgg taaggttatt tttaagacca gcgtgtcaac aggagcaaag gaaagtccaa
    39961 caccgacagg gacctttgtc attgagcctg agcgaggaga ctttttcttc aatcaggcat
    40021 cagaagaggg agcttattat tgggtgtcct ttaaggacca tgggatttat ctgtttcaca
    40081 gcctaccaac agaccaatat ggcaatgaga ttccagagga ggcagagaga ctgggacagc
    40141 cagcctcaca tggctgtgtc cgcatgagca gagcagacgc caaatggttt tatgacaata
    40201 tcccagaagg catcagcgtc acaatagaat agccctaatc tccctcagaa tagcctgagc
    40261 agatagagga agagcctgtt aatattagca ggcttttaaa gctccttaaa aggctgcaaa
    40321 aaggaacgaa aaaagacctg aaacaggtcc attgatctaa gagaagacaa gtaactagcc
    40381 ttctagcaaa gtgttttaaa aatgcgttag tttagtagct tcgtgataat acaattaata
    40441 atatttattt aaaaaaactg taaatttcga ccactgttcc tggatttttt catttaaacg
    40501 tttatgccat gacttatgag cattctctct aatttctttt aggtatatat tttctactac
    40561 ccttttttga ctatgttctc gctctttttt tatttgctgt cttaaattct cttgtttttt
    40621 ctgttcttct aactcttttt gagctttctt ctgttcttgc tctattatgt cttgaggttt
    40681 agattctcct acaatccata tttctgaacc taagacaaaa ccatctgagg taatatgaac
    40741 tctaaattta tcaccattag aagcaatttt attatatgga acatatgttt cttctttgga
    40801 atttgttttt tgtgttctcg ctgattctaa agagaacaca atttttccat cccactttgc
    40861 aattggatag taccggttat ttgttaagtc accattgctt tttttttgga cttgtactaa
    40921 ttcagtttcc ttatcatctt cttcgacttt aaatattcta atcaaagatc ctggactagt
    40981 ttttactact atttctttgt cattattttt gattggttta acgccaaagt ctcgagcgtt
    41041 ttcccaatct cttctaaatc ctattacctt ttggtcacca atttgtggtg cttctgtata
    41101 atcatcataa ccataatagc cttgccctaa aactggagaa ttttcataat cactatttgc
    41161 acttacttcg ttgaaacata ttaaacttag taaaggtaaa ttaacgatta aactcatcac
    41221 taacttcttc ttcatttttt ctt
//
LOCUS       DARYLJ010000014        40158 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYLJ010000014 DARYLJ010000000
VERSION     DARYLJ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40158
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            310..2454
                     /gene="pnp"
                     /locus_tag="TU746_000668"
     CDS             310..2454
                     /gene="pnp"
                     /locus_tag="TU746_000668"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL0891035.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
     gene            2447..3199
                     /locus_tag="TU746_000669"
     CDS             2447..3199
                     /locus_tag="TU746_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL0891036.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            3211..3747
                     /gene="cysE"
                     /locus_tag="TU746_000670"
     CDS             3211..3747
                     /gene="cysE"
                     /locus_tag="TU746_000670"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL0891037.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            3865..5208
                     /locus_tag="TU746_000671"
     CDS             3865..5208
                     /locus_tag="TU746_000671"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL0891038.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            5201..5608
                     /locus_tag="TU746_000672"
     CDS             5201..5608
                     /locus_tag="TU746_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL0891039.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            5825..6613
                     /locus_tag="TU746_000673"
     CDS             5825..6613
                     /locus_tag="TU746_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891040.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            6662..7408
                     /gene="rlmB"
                     /locus_tag="TU746_000674"
     CDS             6662..7408
                     /gene="rlmB"
                     /locus_tag="TU746_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL0891041.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            7409..7927
                     /locus_tag="TU746_000675"
     CDS             7409..7927
                     /locus_tag="TU746_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL0891042.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            8111..8971
                     /locus_tag="TU746_000676"
     CDS             8111..8971
                     /locus_tag="TU746_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0891043.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            9510..9956
                     /gene="rplM"
                     /locus_tag="TU746_000677"
     CDS             9510..9956
                     /gene="rplM"
                     /locus_tag="TU746_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL0891044.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            9976..10368
                     /gene="rpsI"
                     /locus_tag="TU746_000678"
     CDS             9976..10368
                     /gene="rpsI"
                     /locus_tag="TU746_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL0891045.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(10483..11574)
                     /locus_tag="TU746_000679"
                     /pseudo
     CDS             complement(10483..11574)
                     /locus_tag="TU746_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(11628..12146)
                     /locus_tag="TU746_000680"
     CDS             complement(11628..12146)
                     /locus_tag="TU746_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0891046.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            12299..12583
                     /locus_tag="TU746_000681"
     CDS             12299..12583
                     /locus_tag="TU746_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0891047.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            12592..13077
                     /locus_tag="TU746_000682"
                     /pseudo
     CDS             12592..13077
                     /locus_tag="TU746_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            13129..13416
                     /locus_tag="TU746_000683"
     CDS             13129..13416
                     /locus_tag="TU746_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL0891048.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            13431..13721
                     /locus_tag="TU746_000684"
     CDS             13431..13721
                     /locus_tag="TU746_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891049.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            13714..14076
                     /locus_tag="TU746_000685"
     CDS             13714..14076
                     /locus_tag="TU746_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0891050.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            14076..14432
                     /locus_tag="TU746_000686"
     CDS             14076..14432
                     /locus_tag="TU746_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0891051.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            14776..16320
                     /locus_tag="TU746_000687"
     CDS             14776..16320
                     /locus_tag="TU746_000687"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL0891052.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            16322..17566
                     /locus_tag="TU746_000688"
     CDS             16322..17566
                     /locus_tag="TU746_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0891053.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVVNFRR
                     GSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVPKGTV
                     IVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFARGST
                     LKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQYAYFR
                     DKLLTFTAEGVYTDSTVQTRPN"
     gene            17571..18176
                     /locus_tag="TU746_000689"
     CDS             17571..18176
                     /locus_tag="TU746_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0891054.1"
                     /translation="MTWVFGPIKVELGAVCDVVRGNGLQKKDFVNEGYPVIHYGQIYT
                     FYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVGKALVWEGAEDVCIGGH
                     SCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKNLEKAIIILPPVYEQGR
                     IVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
     gene            18191..19399
                     /locus_tag="TU746_000690"
     CDS             18191..19399
                     /locus_tag="TU746_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL0891055.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     AAIYLSDVIGSAENTDLKFVVSTHQALFYNLLYNEIRFDRRIKKKVFYVMKATDEIED
                     EKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYG
                     RWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNS
                     FDSIYRFKED"
     gene            19402..22497
                     /locus_tag="TU746_000691"
     CDS             19402..22497
                     /locus_tag="TU746_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL0891056.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            22665..24116
                     /locus_tag="TU746_000692"
     CDS             22665..24116
                     /locus_tag="TU746_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL0891057.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
     gene            24478..24765
                     /locus_tag="TU746_000693"
     CDS             24478..24765
                     /locus_tag="TU746_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL0891058.1"
                     /translation="MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERV
                     VEEKDLPIKTAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
     gene            24755..25093
                     /locus_tag="TU746_000694"
     CDS             24755..25093
                     /locus_tag="TU746_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0891059.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVDILRIRSTKTDYLN
                     DLENLFNNIL"
     gene            complement(25685..25846)
                     /locus_tag="TU746_000695"
     CDS             complement(25685..25846)
                     /locus_tag="TU746_000695"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0891060.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
     gene            complement(26460..26603)
                     /locus_tag="TU746_000696"
     CDS             complement(26460..26603)
                     /locus_tag="TU746_000696"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0891061.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            complement(26904..27947)
                     /locus_tag="TU746_000697"
     CDS             complement(26904..27947)
                     /locus_tag="TU746_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL0891062.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            complement(28024..29034)
                     /gene="galE"
                     /locus_tag="TU746_000698"
     CDS             complement(28024..29034)
                     /gene="galE"
                     /locus_tag="TU746_000698"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL0891063.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            complement(29044..30528)
                     /gene="galT"
                     /locus_tag="TU746_000699"
     CDS             complement(29044..30528)
                     /gene="galT"
                     /locus_tag="TU746_000699"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL0891064.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            complement(30532..31704)
                     /locus_tag="TU746_000700"
     CDS             complement(30532..31704)
                     /locus_tag="TU746_000700"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL0891065.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            31845..32846
                     /locus_tag="TU746_000701"
     CDS             31845..32846
                     /locus_tag="TU746_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0891066.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            33011..33892
                     /locus_tag="TU746_000702"
     CDS             33011..33892
                     /locus_tag="TU746_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL0891067.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            34517..36064
                     /locus_tag="TU746_000703"
     CDS             34517..36064
                     /locus_tag="TU746_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0891068.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            36391..37314
                     /locus_tag="TU746_000704"
     CDS             36391..37314
                     /locus_tag="TU746_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL0891069.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            37329..39740
                     /locus_tag="TU746_000705"
     CDS             37329..39740
                     /locus_tag="TU746_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0891070.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVKEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
BASE COUNT        12025 a         7384 c         9031 g        11718 t
ORIGIN      
        1 gcaggtcttt ttttgctgcg tcatcagcgg cttagcgtgc ttggctgtag ggctatagtg
       61 ataaaagaga gtgctgctgg tattgacagc cctttcaaac tttttctagg aatgcctttt
      121 agggtcgtga atttttaact attttatggt aaaatgtagc agatacgtcg tttgatacaa
      181 agaggagtgt gtaattcctt acagattgct ctttgtagca aaacaacgta tagccataaa
      241 aaataaaagg ctagcaagct ttggtcgggt caaacggcta tggtaggcta gctcgttcaa
      301 ggagaaagaa tgtcaaaaca aacatttaca acaacctttg caggcaaacc acttgttgtt
      361 gaggtcggtc aagtagccaa gcgagcaaat ggtgccactg tcgttcgtta tggggagtct
      421 acagtgctaa ctgctgctgt catgtctaag aagatgtcaa caggagactt tttcccgctt
      481 caagtcaatt atgaagaaaa aatgtatgcc gcaggtaaat ttcccggtgg ctggatgaag
      541 cgtgagggac gtccgtcaac agatgcgacc ttaaccgctc gcttgattga ccgccctatc
      601 cgtcctatgt ttgctgaggg ctttcgtaat gaggtccagg tgattaatac tgtcctgtct
      661 tatgacgaag atgctagtgc ccctatggct gctatgcttg gtagctcatt agccctatcg
      721 atttcagata ttccttttaa tgggccgatt gctggtgttc aggtggccta tgttgagggt
      781 gaatttatca tcaatcctga taaggcccag caggaggctt cattattaga gttaaccgta
      841 gcaggaacaa aagatgcgat caatatggtt gaatctggtg ctaaggaatt gccagaggct
      901 attatgctag aagcactttt ggttggccat aaggctatac aggagttgat tgcttttcaa
      961 gaagagattg ttgcagcggt gggcaaggaa aaggctgagg tagagctatt acaggttgct
     1021 gctgatttgc aggctgagat catagagact tacaatgctg atttgcagca ggctattcag
     1081 gttgaggaga aaaaagcacg tgaagccgca accgaggctg tcaaggagcg tgtcatagct
     1141 gcatacgagg agcgttatgc agcagacgaa gagcatgacc gtatcatgcg tgatgtggct
     1201 gaaattttgg agcaaatgga gcatgctgag gttcgtcgcc tcatcactga ggataaggtt
     1261 cgtcctgatg gtcgtcgtgt tgatgagatt cgtccgcttg ctgctgagat tgatttctta
     1321 ccaagggtgc atggctcagg cctctttacg cgcggtcaaa ctcaagcttt gtctgtcttg
     1381 actctagccc caatgggaga tactcaaatt attgatgggc ttgagcctga gtacaaaaaa
     1441 cgcttcttgc accactataa tttccctcaa tattctgttg gtgagacagg ccgctacggt
     1501 gcagcagggc gtcgtgaaat tgggcatggt gctttaggcg agcgcgctct tgcacaagtc
     1561 cttccaagcc ttgaggcatt tccatatgct attcgtctag tggctgaggt attggaatca
     1621 aacggttctt cctcgcaggc ctctatctgt gcagggacgc ttgctttgat ggctggtggt
     1681 gtgccgatca aggcaccggt tgcgggtatt gctatgggac ttatctctga tgggaccaat
     1741 tatactgttt taacagacat tcaggggtta gaggatcatt ttggcgacat ggacttcaag
     1801 gttgctggga cacgccaagg gattacagca ctgcaaatgg atatcaagat cgaaggtatc
     1861 acccctcaaa tcctagaaga agccttggcg caggctaaaa aggctcgctt tgaaattctt
     1921 gacttgattg aggcaaccat tgctgagcct cgtccagaat tggcaccaac agcaccaaag
     1981 attgatacca tcaagattga tgttgataag attaaggtgg ttattggtaa gggtggcgaa
     2041 accattgata agattattgc tgagacaggt gttaagattg acattgatga ggaaggaaat
     2101 gtttcaatct actcaagtga tcaggacgct atcaatcgtg ctaaggaaat cattgctagc
     2161 ctagtacgtg aggctaaggt aggagaggtc taccatgcta aggttgtccg tattgaaaaa
     2221 tttggtgcct ttgttaacct ctttgacaag acagatgcgc tggtgcatat ctctgaaatt
     2281 gcttggagcc gcactaccaa tgtctcagat gttcttgaaa tcggtgaaga ggttgacgtt
     2341 aaggttatta aggttgatga taagggacgt attgacgcat caatgaaagc cttggtgcca
     2401 cgcccgccaa agccagaaaa atcagaagca aaaaaagaag gcaaacatga ctaatacaaa
     2461 tgaactagat attcgtttaa gagcctttat caatgcccct gataattttt tagatagcgt
     2521 ggccttggtt aatgcttttc accagtatcc ggtgtgggca gcaaaaaagc cctatgctat
     2581 tgagattgaa ggggtaagga tttttcctgt attcacagat aaggacgaca tggcgacctt
     2641 taaagaggag caaaagagtg cacaagctca gtattgggta gagcgctctg ctcttactgt
     2701 cttggaggag gctgttcatg caggtgctgc tgggctaggc tttaatctca agaaaaaggg
     2761 agattttggc aattctacag tgttcaagtc tgctgatatg attcagttta tgaacaatta
     2821 cacaacgatt ttgaatacct tgatgagtga tgacaatagc gcagcagata ccctggatag
     2881 gctttatctg gtgccggcct ttgtttaccc taaggaagag gagcattact atgacaggct
     2941 ttttccaacc atgtcaactc cagaggggaa gcgttatgtt cctgcctttt caaatcttca
     3001 gagcttcgct aaatggtaca atcaagagga gtttggcggc ctttttagga aatcaggtgg
     3061 tgttatctta acatggaaga tagcagacat ttatcagcca agaaatggca ataatgacat
     3121 agacgagacc tttggggttg ctattgaccc ctttgatgat cagcagattc ttgttgattg
     3181 gtctgatatt gacacataaa aggagtttaa atgggctggt ggaaggacaa tattgatatt
     3241 gtaaagcaac tagatcctgc tgcacgtagc accctagagg ttatcctaac ctaccctgga
     3301 ttaaaggcct tggcagcgca caggctgtca cattttttgt ggcagcatgg ctttaagctg
     3361 ctggctcgaa tgcatagcca gttttggcga ttttggacac agattgaaat ccacccagga
     3421 gctaggattg cttcaggtgt tttcattgac catggggctg gcttggtgat tggtgagacg
     3481 gccattgttg aaaaaggagc catgctttat catggagtga cgcttggtgg aactggaaaa
     3541 gatcgaggga agcggcaccc tactgttcgt gagggggcac tgatttctgc ccatgctcaa
     3601 attatcggtc ctgtcgagat tgggaaatcg gctaaggttg gagctgcagc tgttgtgttg
     3661 actgatgtac ctgctggcgt gacggtcgtt ggcattccag cccaaattgt tcgagtgcat
     3721 gagaaaaagc cctcaaggca ggattaatag ttttctctag aggcagtcag ccaaaaaacg
     3781 ggagagttag agccctatgc ttacctcagt tgctgacagc ttgcgcagtc taggagaaaa
     3841 ggataaaaac aaaagggaaa agtgatgata aaaatctatg ataccatgac cagaagtctg
     3901 cgagagtttg taccaataac tgataaggtg gtcaatatgt atgtctgcgg gccaacggtt
     3961 tacaattata ttcacattgg caatgcacgt tcggctgtgg cctttgatac gattcgtcgc
     4021 tactttgaat acgcaggcta tacagtcaat tacatttcaa attttacaga tgtagacgat
     4081 aagattatca aggcagccaa ggaatcaggt gtatcaccca aggaattggc ggacagattt
     4141 attgctgcct ttatggagga taccaaggca ctcggtgtga agccggccac caaaaatcca
     4201 cgcgtcatgg actatatgga cgagatcatt gcctttatcg ctgctttaat caaaaaaggc
     4261 tatgcctatg agtcggcagg tgatatttat ttccgcgtgg caaaggcatc aaattatgcc
     4321 agactggcta ataaaacgat tgctgatttg gaggctggtg ctagtggtcg tacagatacc
     4381 gaaactgctc tcaaggaaga tcctttggac tttgccctat ggaaatcagc aaagctaggc
     4441 gagatttctt gggcaagtcc ttggagcgcc ggtcgtcctg gctggcatat cgagtgctct
     4501 gtaatggcaa ccgagctttt gggagatacc attgatattc atggtggtgg cgcagacctg
     4561 gaattcccac accataccaa tgaaattgct caatcagaag caaaaactag caaaactttt
     4621 gccaattact ggatgcataa tggctttgtt aatgttgaca acgaaaaaat gtctaagtca
     4681 ctgggcaact ttgtgactgt tcatgatctg ctaaagacgg tggatgggca aacgctacgc
     4741 tttttcttgg ctactcagca ttatcgtaag ccgattaatt ttactgaaaa agctattcat
     4801 gatgctggag ttaacctcaa atacttgaaa aacacgcttc agcagcccac agtagccact
     4861 gcagatgcta gccagcttgc tgcctttatc actgccttca aagcagccat gaatgatgat
     4921 tttaatacag caaatgggat tacagtctta tttgacatgg caaaatggat taactccggc
     4981 gcctattctg aggctgtcaa atcagcattt gaagagatgc tagctgtttt tggcattgtc
     5041 tttgaagcag aaagcctaga cacagagatt gagcagctga ttgctgagcg tcaggaggca
     5101 cgtgccaatc gagattttgc aagggcagat gctattcggg atcagttggc agctcagggg
     5161 atcaagctgt tggatacaaa agaaggtgtg aggtggatac gtggctaatt cagttgatgt
     5221 caatttgatt aatggcattg cccttgcctt tgttggtgat gctgtttatt cttactatat
     5281 tcgtcgtcat ctgattttcc aaggccagac caagccaaat aagctccact accttgcaac
     5341 aaaatatgtt tctgcaaagg cacaggcttc tctgattcag gccatgctag aagcacaact
     5401 attgaccgaa aaagaaaaag acatctacaa acgaggccgc aataccaaca gccataccaa
     5461 ggctaaaaat gctgatgtag taacctatcg tatgtcaaca ggctttgaag ctattatggg
     5521 ctaccttgat atgacaggtc agacagaacg gctagaactg ttgatccagt ggtgtatcaa
     5581 gcaggtggag aacagtcctc aatcataatg atgaatcatc taaaacattc tctgtgtcac
     5641 tagcgatctg ccatcgctca aagtcatgag agtgttttta tgttgtgttt aaaagttatg
     5701 tcacaatata gatacacacg aaacataaaa taaatatttg taacaaaaac gtaacaaaac
     5761 tattgaaaaa ttttccgaat agtttataat gaaagagtca taataaaatg ataggagaat
     5821 gtctatgaaa ccaatgagaa acgtagcctt agttatttca gcaatgttac tgttaagctc
     5881 acaggccttt gtatcagcag tagcagcaca ggacaatcaa ccaaccatag cagttcaagc
     5941 acaggcagca gctgaggcca atgtcagtgc tcgtatgcgt tcagatcagc ccgttattga
     6001 agctaacatt gctaccagtc agccagttag ccaaagcact gaggctacta ttttactaaa
     6061 ggatgccaaa ggcaacgcga ttaatagcac agcctatacc atgcaggctg gtcaaagccg
     6121 gttttcagta tggtttgacc ttacgaacct aaaggttagt gattatagta tatcagtgag
     6181 tgttcctgat aaagaaaagg cctttagtgg tagctcagca cctattcatt ttgatggaaa
     6241 gccaaccaaa aataccccag agacagaaca gaaaaacagc aatccagtac cagctaataa
     6301 ccagcctaaa cccgctgcta gcggcagggt gacaagcact gagcaacccc aaaatgtgcc
     6361 tagcgcgact gctagcgcca atcatatgac aagaaccaat catcgatctg ataaggtcct
     6421 aaaggcaagc tcaagcaaca caccatcagc tgccaaatca atagactctg ctgagaaagg
     6481 caagggcatg ctttctgata gcacagccca agataaagag caaaaaggct ttccttggct
     6541 gctatcatct ctaattgcaa ttacagcagc tgctttactt gctcttgtca tcaaagctgt
     6601 tcacaggaaa taaaaagagc agcaagagct attttattgc tttcgtggta taataaaaac
     6661 catgaaagct aaagaaatca atgaaaccaa ggatattgtt tatggcgtcc atgccgttac
     6721 cgaaagccta ctagccaata ctggaaataa gctttacatt caagaggatc tgtgtggtaa
     6781 gcatgttgat cacatcaagg atttagccac tagtaagaag gtgtctatct cttggacaaa
     6841 aaagaaagct ttgaccgaaa tgacagcagg agctgttcat cagggctttg cgcttcgagt
     6901 gtcagccttt gcttatactg agctagatga gctgctagag ctggcacagc aggaggataa
     6961 tcccttgctg ctcatcctag atgggctgac agatcctcat aattttgggt ctattttaag
     7021 aacagccgac gcaacaggtg tttgtggtgt gattatccct aagcatcgtg ctgttggtgt
     7081 gacaccagtg gttgctaaga cctcaacagg agctgttgag catgttccaa ttgctcgcgt
     7141 gacaaatctt agccaagcat tggatcagct aaaagcaaat ggcttttggg tcttcgggac
     7201 agatgtaact ggtacaccat catacaagtg gaatacctca ggcaagctgg ctttgattat
     7261 tggcaatgag ggtaagggca tttcagctaa catcaaaaaa caggtagatg aaatgattac
     7321 cattcctatg atgggtcatg ttcagagctt aaatgctagc gttgcagctg ctattttgat
     7381 gtatgaagta tttagaaata aattatagat gaaaaaaaga ctattgctgg ttgatggcta
     7441 taacatgatt gccttttggg aatcaactcg tcagtttttt aagacaaacc aattggatca
     7501 agctagaagg atcttgctaa ataagctgaa caactatgcg cattttgatg atagtgacat
     7561 tatttgcgta tttgatgctc agtatgttcc aggacttaga cagcgttatg accaatatag
     7621 gatttctgtt atttttaccg aagaggaaga aacagctgat agctatattg agcggactgc
     7681 tgctgagcta aacaccgctc taaccatggt agaggtggct actagtgatc tgaatgaaca
     7741 gtggacgatc ttttcccaag gcgccttgcg tgtcactgct aaagagcttg agcagcgtgt
     7801 taatgctgtt aagtcggatt tagataagct gtcacaggat attgatctta aaaagcctag
     7861 actgggtccc tttgatcaag ggcagcttaa tcagctcaag gactttatga atcgattaga
     7921 tgattaataa gcttatcttg ctagcttttc taggtatgat tctccaggct gctagagcag
     7981 ctcatacgat ctaacggtga tcatttctga ggcagctggt tcttattgct ttcttagctg
     8041 atattttttt gttatactat gagaaaatca tttgattatt aaacgataat gacgttactt
     8101 gggagttcag atgacatttg tattgatgac agattcaaca gcggatttag attctttttg
     8161 ggcaaaggag cataacatcg atatagtagg cctaactgtt gaatgtgatg gcaaggttta
     8221 caagacggtt ggtccagata gattaacgag tgatgctttg ctagctatga tgaaaagtgg
     8281 gagccagccc aaaacaagcc agataaatgt tggtcagttt gaagagattt ttcgacatta
     8341 cgcagctgat aaccaagctc ttttatatat cgccttttct tcagtcctat caggtaccta
     8401 tcaaagtgct gtcatggcac gtgagctggt tttggaggac tatccggacg ctgtaattga
     8461 gattgttgat agcttggctg cagcaggagg agagggctat ttgaccatgc tagcctcgga
     8521 ggcgcgtgat aatggaaaaa gcctattaga aaccaaagcg ataatagaag gtattttgcc
     8581 tcgcttacgc acctatttct tagtagatga tctttttcat cttgtgcgag gaggacgctt
     8641 gtcaaaaggc tctgctttta taggcagcct agtgaatatt aagcctctct tatggattga
     8701 tgccagcgga aaattagttc ctattgccaa gattcgtggc cgtaaaaagg ccattaagga
     8761 aattgctgac agagccacaa aagatattgc tgattcaact gttgttgtgt cctatactag
     8821 tgatcagact ggggcagatg acctacgaga acagctatta gcacatgaag gtatcagtga
     8881 tgtctttatg ctgccgctcg gaccggtgat tgctgctcat acaggtccag ataccttagc
     8941 ggtctttgtc atcggcaagg aaaaaagata aaaagaaaag gattgaagcg cttgtttcaa
     9001 ttcttttttg tcgactatag cttgttttag ctgtgatgcc gcttaagagt atgggtgttc
     9061 gcatttttta tttttaatca aaagttagaa tgaattgttt gacaatgaag gtgcgcgtgc
     9121 aggtaaggaa ctagcataac agaacagggc tttttgattt gccagaagtc agatgtcaaa
     9181 tgttttagca gttgacagga gctttggtca ttccaccact aatctttgta ttgttatttg
     9241 cataggagct aacaggaact gagcggattt tttggaggga agtcaaggct aatagtccag
     9301 ctcaaaagca agcctgttct tcttgtgaaa aagcaaaaat aatcaaagaa atagagctaa
     9361 accacttgac tatcagttaa gaagtttgat actatagtag acggtattgt ttaccccatt
     9421 tgaaaggccc cggaaccttc caaatacctt cgatggaccg gaacatccat cactaatgta
     9481 aacaaaaacg aattcgtata ggagaaatca tgaacaaaac aactttcatg gctaaaccag
     9541 gccaagttga acgcaaatgg tacgttgttg acgcaacaga tgtgccactt ggacgccttt
     9601 ctgcagtagt tgctagcgta cttcgcggaa agaacaagcc aactttcaca ccgcacactg
     9661 atacaggtga ctttgttatt gttatcaatg ctgagaaggt taaattaact ggtaaaaaag
     9721 caactgataa ggtttattac actcactcaa tgtacccagg tggcttgaaa tcaatcactg
     9781 ctggtgagct tcgctctaaa aatgccgttc gtttgattga aaagtcagta aaaggcatgc
     9841 ttccacacaa cactcttgga cgtgcacaag gtatgaaatt aaaggtcttt gttggcggtg
     9901 agcacactca tgctgcacaa caaccagaag tacttgatat ttcaggactt atctaagaga
     9961 aaggagcatt aaataatggc acaagcacaa tatgcaggta ctggtcgtcg taaaaacgct
    10021 gttgcacgcg ttcgtttagt tccaggtact ggtaaaatca ctgttaataa aaaagatgtt
    10081 gaagaataca tcccacatgc tgacctacgt ttagtcatta atcagccttt tgcagtgact
    10141 tcaactgaag gctcatacga cgtttttgtt aacgttgtag gtggtggtta tgctggtcaa
    10201 tcaggtgcga ttcgtcatgg tatcgctcgt gcgcttcttc aagtggaccc agatttccgt
    10261 gactcactaa agcgcgctgg tcttcttaca cgtgacgcac gtatggttga acgtaaaaaa
    10321 ccaggtctta aaaaagcccg taaagctagc cagttctcaa aacgttaata tccagttata
    10381 ccaacgtttc agagcacttt gcgaagtttt cgcaaggtgc ttttttgttg aaaaaagcac
    10441 cttggtaatc tgttgagacc tagttttaag agaggttaag ttagaatgac tataagtatc
    10501 taaagtcatc tggctgctag catgacctag acgcttagcg gtattaactg ggtcaattcc
    10561 catttcaatc atcaaggttg cgtgagtgtg cctaaaccca tgtgggctaa tctttttaag
    10621 attatgcttt cgtataatgc gttttagaat attgttgata tagtcagcgt gtaagggttc
    10681 tatctcacca tctctgttgc agtatgtaaa cataaattct ttgtcgagag aaaggggctg
    10741 tactgataat tgcccctttt ctttgctagt ttcctgtttc catttgttga ggatagaaca
    10801 ggtttcatca tcaagataga tagagcgtac tgagaatgta tttttagttc ctttttcaat
    10861 ggcatgacca tctattcttc ctaaactttt gctgactgtt aatagttgat tctcagaatc
    10921 aaaatcttcc catttgaggg cgtagagctc tccttttcgt aacccgctgt atgctagtaa
    10981 tcgaaataga gcataatgtt tataaggttc attttctaaa atgattgtca aaaaatgatg
    11041 caactcgtta actgtccagt agttctcact gacagttttt ttgagtttag gcataataac
    11101 tttgctcata ggattacgtt caatatgatt catattgatg gcaaattcaa aggttttaga
    11161 ggtgtatgac ttgatttgct tcatgttctt gaatgatttc gctttatctg tgataaaggt
    11221 ttggcagtct agcggactga tttttgaaat ctttttctct ccaaaggttg gaagaatatg
    11281 aaggcgatat aaatcggccg ttttagctgc agtagttgtt tcaacggtat ctttgtaagc
    11341 ttcataccac ctttgatata gttcttggta agtataggtt gtttgagcag taagatgggc
    11401 aaaagttcca ctattcagct gatgattaac agcagtttca tgagctttgg cagctttacg
    11461 cgtcttgaat cctcgtttag tgtaatattt tttcttaccg tagtcgttta gaccaaggta
    11521 aactttaaca aaataggtaa ttccttttgt agattggtat ttgtgtacag acataacagt
    11581 tctccgtttc taagttttcg gagcttatgt aattgagaaa tattagtcta ttttctgtca
    11641 cgatctgctc gtctaatttg aaactcttcg gtttgtatcc atgttttcca aatatccgat
    11701 ttttggcctt ggttattcat aaacttaatt aagtctttga taaaggtttc ttcataatcc
    11761 attaagtagt tagaaagaat acgtctaaag tcatctgaga aaacctcgtt taagggcata
    11821 gacaaatgaa tctctcctag ttcgattcct ttcttaagct tctccatatc gcttttaaaa
    11881 ggtgttacag aagtaatttc agatgtcttg aaactatcag tgacgatttt taaatttgac
    11941 ggagcgtact tttcttcgtc aattccaagg atgtatgcca ctgagacacc aaaataatcc
    12001 gctaactttt gagcattctc ttttttaggt tttcgtattc cttggttata gctagatagt
    12061 gttgggtagg atatatctag cgcttcactg atacttttta tttttttgcc actttcttct
    12121 ataagtttag ctatattatt agtcatagat tcctcctaat tgatattcta ccacatttaa
    12181 tacaaaaagt ataataccac ttgacaagaa tacaaaaagt atttataatt taaaatgtat
    12241 aataaaatat acaaatttcg gagtttattt aattgagaaa tggaaacgag gtaatgatat
    12301 gtctgaagaa gcgactttag ttgttcaact tcccaaagtt ttggaaaaac aattaagggc
    12361 acattatgat gaaatggttt ctacagctat tgaaagagcg ctagaggata aagaattata
    12421 taaacctatg gttcggatgg cagccctttc tagatggctt gatgtgtcaa cgacaacact
    12481 tcaaaagtgg acgcgagaag gaatgcctac aatggttatt gatggtgtga ctctgtacga
    12541 taaacgtgcg gttacacgtt ggttgaagca atatgaaaga tgaggtaaag aatggctaat
    12601 agacgaatgt tgagtaaaac ggtggtgcag atacaacgat ttttacgcct accacttgaa
    12661 gcgcaggcgc tttactgtca cttggtagtc aatgcagatg atgatggtat tgttgaagct
    12721 tttcctgtta tgcggatgat taatgctaat gaggacagtt tgaatttatt aactcttaag
    12781 cagtatttac tcttgttaaa caatgaaatg gtttacttta tcaaggattt ctttgagcag
    12841 aataccatca aagcagatcg ttacacaccg agtagtcatc gtcaacttct tatagattat
    12901 ctgaaggata atcagttgtt ggagtgtcta aatctaggac cacgcttgat taattatctt
    12961 caaaatactc ggctccaagt tggagccagt ctggatccag atgggaaccg caatataatt
    13021 aaagataaga taagtaaaga taggataggt aaagataagt taagtcaaga taagatagga
    13081 ttagataatg atccaatctc atcacaactg actgatgaca tctggttaat ggaaacacta
    13141 tggcatcgag aattaaccca acaggagaaa gtattattag aaggattcgc ggttaatgat
    13201 tctttattgc agttagctat tcagaaaaca gaggagcttg agccaaagaa acaaaacatg
    13261 agttatgtca aagggatact aatgaattgg gaagctagag ggtttataac tgttgaccaa
    13321 gtgatagcat ctgaagaaga ctaccgtcca ttagaaattg caaatgtaga agtttcagaa
    13381 gatttcttag cagctatgga tatatggaaa gactagggga ataatgagtt atgacagtat
    13441 attatcaatt agaaaatatg ttagtggctg ggtttaagtc acaagatgag tacgaccgct
    13501 atcaggctct caagagggac tatgaagggg agtcagagga ctatagcttt tcaatcagag
    13561 aaatcacaaa tcaacttgaa atcatttgtc agacctcaga gaatgatttt ccgaacttat
    13621 cagaagcatt aatgattgat tatttagaac tggtaggaga gttgaaacga tatgatacta
    13681 atcaggcaga caggtattta gggatggttc gtcatgtctg aacgtatcag aactatttta
    13741 aagaagtttt atgtgacgga attgcagaat gaagtactta atcaactagt aaatgataca
    13801 ggcttgcaaa cattctctaa ttatgctcgt cggatgcttt ttaaggaaac atcactcttt
    13861 atgcgatttg atgaatctca gtttgatgag ttgatttatt ctttaaggcg tattcaaaat
    13921 aatttaaggc agttatctaa aattgcagag cagtctcaag atagtcaagc ctacagagct
    13981 atggactata gcagaaggtt agtttcacat tatgaaaagc agttaacgcg ttaccacaag
    14041 aaaaagaaac ggaaattatt atctaaggga gcttaatgga taaaaggaga attaggaacg
    14101 taattaaaca agtctttttg tctgaagaag aaaatcaaaa actgttagag aaaatgaagc
    14161 aagatggctt cacaaacttt tctctttttg ctagaaagca attattaaaa cctgattttg
    14221 aaacttggct agttagtttt ccagaatatc agccgctgac tggcaggtta ctatctgttg
    14281 gtagaacaat taatggcatc gctaaaagcg caacacagtt tggaaaaatt tcccaacatg
    14341 atttgatgga attaggtcag ttgatggagg aacttgtaga actggtagag aaacaagtga
    14401 aggaagacaa gcaacgaata gccaagaagt gatagtcgtt cagtcatttt ggtagaatag
    14461 ttttaaataa aacaacaaaa acgctgatgg tagtcagcgt tttttagcat gtaattgtaa
    14521 aaaatccttg tacggacaat gtgcggcacc gtataaagta cgggaaatca ctaaaaatgg
    14581 agttaggtct ttgcgagctc agatagtgta tacacactat cgtaaaaata gaaccatcag
    14641 taaaggtcag actgacactt tttgattgat gcttatattt tattttgggg caaagcccca
    14701 aaccccttga gaaaacgtgt gagaagtagg gaaaaatggt ataatagaaa tattaaagac
    14761 tgtgaggatt tgaagatgtc agaacaagca caaaggcaag agttgcaccg caaaatctgg
    14821 gcaatcgcag atgatgtccg tggtgcggta gatggttggg atttcaaaca atatattttg
    14881 ggaatccttt tttaccgttt tatcagtgaa aatttcaaga cttatatcga gggtggtgag
    14941 gacttcaact atgaggagat tccggatgaa gtaatcacac ctgaggttaa ggatgatgcg
    15001 attaagacaa aggggtactt tattatgcct gcgcagcttt tttccaatgt tgtgaaaaca
    15061 gctcgtagta atgacaactt aaatacggaa ctcaaggata tttttgatgc cattgaggcg
    15121 agtgctatgg gttatgccag tgaaaatgat attaaaggtc tttttgatga cgtagacacc
    15181 agaagtaata agctaggaag taccgtccca gagcgtaatg aacgcttagc ccttatccta
    15241 gaaggtattg ccagccttga ttttggtagt ttcgaggaca atcatatcga cctttttggc
    15301 gatgcctatg agtttctgat ttctaactac gcttctaacg ccgggaaatc aggcggagag
    15361 tttttcacac cgcagagcgt gtcacggctc ctagcacgta tcgtcatgtt aggcaaggat
    15421 gaaaagaaca aaatcaataa gatttatgac cctgcttgtg gttctggttc tctcttgctt
    15481 caagccaaaa aacaatttac ggagcatatt atcgaggatg gtttttatgg tcaggaaatc
    15541 aacatgacca cctacaactt ggctcggatg aatatgttcc ttcataatat caactacgac
    15601 aagtttagca ttgagcgtgg caatacgctg ctggacccta agcatggcaa tgataagccc
    15661 tttgatgcta tcgtgtccaa cccgccttat tcaatcaagt gggttggtag cgatgacccg
    15721 acgctaatta atgatgaccg ttttgcacca gcggggattc tggcacccaa gtctaaagcg
    15781 gattttgctt ttatcatgca tagcctttct tatttgtcca ataaaggcag agcggctatt
    15841 gtgaccttcc ctgggatttt ttatcgtggt ggagcggagc aaaagattcg tcagtatttg
    15901 gtagacggaa actttgtcga aactgttatc caattgccgg ataatctcct ttttgggacg
    15961 tctatcgcta cctgtatcct tattcttgct aagaataagc cgacaacaga tgttctcttc
    16021 attgacgcta gccagcagtt caaaaaagaa accaataaca atgtcttgac agaagagaac
    16081 atcgagaaaa ttctgaaaag tgttgagcat aagaataatg aagagtattt tgctcagctc
    16141 atttcccaag aaaaaattgt ggaagctgac tacaatctct ctgtatctac ctacgtggaa
    16201 aaagaggata cgcgtgagaa gattaatatt gatgtattaa acaaagaaat tgctgagacc
    16261 gtgaaaaata ttgaccgatt gcgggcagag attgataaga ttgtcgagga gttgagctga
    16321 tatgacctac attgatgaga tgattaaaga gctttgtcct gacggagtgg agtggaaaga
    16381 gttgggtgaa gtcgttgact acgaacagcc aacaaagtat atcgtaaaat ctaaggaata
    16441 cagcgatgat tattccattc cagttttgac agcaggtcag acatttattc ttggatacac
    16501 aaatgaagta actggtattt atccagcaag taaggaacat ccagttatta ttttcgatga
    16561 ctttacgaca gctagaaagt gggtggattt tgaatttaaa gttaagtcct cggcgatgaa
    16621 actactctct atcaagtcag accgtcaaga tgatgtttca ataaggtatg tttggcacta
    16681 tttaggaaca ataaaataca caccagaaca gcacgcacga cagtggatag ggactttttc
    16741 taaatttaaa atcccccttc ccccactaga aattcaaggg gagatagtta aaatacttga
    16801 caaattcacg gaacatgtta cagaattgac cgcagaattg acctttcgac agaaacaata
    16861 ttcttatttt agagataagc tcctaagttt tgatgatgaa agtatgggag gggcgaacga
    16921 taaggtttac actgtccagt ggaaaacgct gggggaggtg gtgaatttta ggagagggtc
    16981 tttccctcag ccttacacag atatgtcgtt ctatggtgga gaagatgccc aaccatttgt
    17041 tcaagttgta gatgttgctg atgaaggatt tagactgaat actaaaacga aaaaaacaat
    17101 ttctcaaaaa gctattccaa aaagtgtttt tgtacctaag ggaaccgtta tcgttacctt
    17161 gcaaggcacc ctaggaaggg tagcggttac ccagtatgat gcttatgtcg atagaacgtt
    17221 agcaattttt gacggttata agcaagaagt tgataaacgc tatttcgcac accaattgaa
    17281 gtttattttt gacagagaaa aagaatttgc tagaggaagt actctgaaaa caataacaaa
    17341 acaagaattc tcgaatttca aaatcccagt ccctcctctg gatattcagc gtcgtattgt
    17401 ccaagttttg gataattttg atacggtttg taatgaccta aatatcgggc tacctaagga
    17461 gattgagctt catcagaaac agtatgccta ttttagagac aaactcttga ccttcaccgc
    17521 cgaaggcgtg tatactgaca gtacagtaca gacaagacct aattaggctc ttgacttggg
    17581 tttttggacc gattaaggtt gagttggggg ctgtctgcga tgtggtgcgt gggaatggtt
    17641 tgcaaaagaa ggattttgtt aatgagggtt atcctgttat tcattatgga caaatctata
    17701 ccttctatgg attgagtgct cgcgtgacga aatcttttgt gtcaccagaa gttggtcaaa
    17761 aattgaaaaa agctaaaact ggtgatgtga ttgtagctac tacttctgaa aatattgaag
    17821 atgttggtaa agcacttgtt tgggaaggtg ctgaagatgt ttgtattggt ggacactctt
    17881 gtgtattgca cacggaacaa aactcgaagt acttgcttta ttattttcag acaactgtgt
    17941 ttcaaaagca aaaggaaaag ttagtgatag gaactaaagt gattgaactg tatcctaaaa
    18001 atttagaaaa ggcgattatt attctcccac ctgtatacga acaagggcgt atcgtctcca
    18061 ttcttgacaa atttgataca ctaacttctg accttaccca aggtcttccg aaagaaattg
    18121 agcaacgaca gaaacagtat gagtattggc gggatttact acttaacttt ccgtaggagg
    18181 aagaatagat atgggaaatg atatcaaatt tgaaaattta gaacagattt cggataatat
    18241 tatttctagt aataagaaag ttcatttgct atatgcctat aatgctactg ggaaaactag
    18301 gctttctatg gaattgaaaa ataaggtaaa tgagactgat agtgatggta atagcattaa
    18361 gcacatttta tatttcaatt catatacgga ggatcttttt acgtgggata atgatttgga
    18421 aaacgatgaa gatcgatatt tgatttatga taaacgaact tattttggaa atttccttga
    18481 agagcaacaa cttttcgaac gtgctgtaga caattttcaa aagtatgttg gtagatctat
    18541 tgatattgag ttccaagatg ttattgaaac agttaaagat gagttcggaa atgttcaaaa
    18601 agataatagg ggtgaggcac taacaattag taataaaaag agtataagat ttaaagtaga
    18661 tgggcataca ataaaggtgt ctagaggaga agagaggatt tttgtttggt cagttttctt
    18721 aacgctcctt gaaattatta ttgaagattt gactgagtct gctgatacct cagaattttc
    18781 aaaaatgaac tatatctata ttgacgatcc tatatcttct ttggatgata ctaatattat
    18841 taatgctgca atttatttga gtgatgttat aggtagtgct gaaaatactg atttgaaatt
    18901 tgtcgtctct actcatcaag cattatttta taatttactt tataatgaaa tccgatttga
    18961 tagaagaatc aagaaaaagg ttttttacgt catgaaagct actgatgaaa ttgaggatga
    19021 gaaacaattt aaatatttgt tgacagatgt tgaaggggat tctccatttg gatatcatct
    19081 cagagtgaga gaagaattga gaaaagcaat tcaagatgaa caggtagaga aattccattt
    19141 tgctcttttt agaaacctag ttgaaaaaac agcaacattt ttaggatatg gacgatggga
    19201 aaatatcttg ttaggtttag atgttgctgg acatgttata acatctgaaa atattaaact
    19261 ctatacacaa ctgattgatt tatacactca taataggcat gctgatttag aatatagaga
    19321 attgcctccc caagagaaaa atactcttat aaatttattt aatagctttg attcaatcta
    19381 tcgatttaaa gaggactaac tatgactgaa atcatccaaa cagatactat tttagaggct
    19441 aagaacttca ttgtactgga aaaatacacc aagttggaaa agcctagcac ctatcagacg
    19501 gaagcagact tggagcgaga gctggttagc gatttgcggc agcagggata cgagtacctc
    19561 aacaatctga cgaccccaga agctctctta gataacctaa agacccagat ggaagccctt
    19621 aatggcgtgg ttttttctga ggcagaatgg ctgcgttttt tagaggagta cctcaataag
    19681 cctagtgatg gtttgattga ccgcacccga aagctccacg ataaccacat ctacgacttt
    19741 atctttgacg atgggcatat ccaaaatatt tatctctggg ataagaaaaa tatcagtcga
    19801 aataagcttc aggtcattaa ccaaatgtct caagttggga cttcaagtaa ccgttatgat
    19861 gtgaccattt tggttaatgg gctaccctta gtacaaattg agcttaaaaa gcgtggggtg
    19921 gctattcgtg aggctttcaa ccaggttcac cgttacagta aggaaagctt taatgaggaa
    19981 aattcgctct tcaagtatct ccagattttt gtcatttcaa atgggacgga tactcgctat
    20041 tttgctaata ccactaagcg agagaaaaat tcttttgact ttaccatgaa ttgggcacta
    20101 aaaaataatg agccaatcaa ggatttgaag gattttacag cgaccttctt cagtcagcag
    20161 acactcttaa acattctcat caactactca gtttttgata ctagtgatac cctcctaatc
    20221 atgcgtccct atcagattgc tgcgacggag cgcatcatct ggaagattcg ttcggccatt
    20281 gatagcaaaa tcaagagtgg tcctgagact ggcggctata tctggcatac gacggggtct
    20341 ggtaagacct tgaccagttt taaggctgcg agactggcga ctgagatgga taaagtggac
    20401 aaggttttct ttgtggttga taggaaagac ttggactacc agactatgaa agaataccag
    20461 cgtttttcac ctgactcagt taatgggtca aatagcacag ctggacttaa acgcaatatc
    20521 gaaaaagatg acaataagat tgttgtgacg acgattcaaa agctcaataa ctttatgtct
    20581 agtgaagcac agcatgagat ttacaacaag caagtggtct ttatctttga cgaatgccac
    20641 tgttcacagt ttggcgaggc tcaaaagcgc ttaaaacaaa agtttaagaa gtattgtcag
    20701 tttggtttta caggcacgcc gattaaagtt gaaaatgctt taggcagtga gacgacagct
    20761 tctgtattcg gtcgggagct tcatgcatac gtcattactg atgctatccg tgaccaaaag
    20821 gtgttgaaat ttaaggtgga ttataatgat gttcgtccac agtttaagtc gttagaaact
    20881 gagcaagatt tagggaaatt atctgctgct gaaaataaaa aagccctact tcatccaaca
    20941 cggattacag agatttcggc ttatatttta gaacatttta atcaaaagac acataggcaa
    21001 aacggtaaag gatttaacgc tatgtttgct gtgtcaagtg tcgaggcggc caaggcttac
    21061 taccaagagt tgcaagacca acaagctgga aaagctaaac cattgaagat tgcaaccatc
    21121 ttctcttatg cagcaaatga ggagcaggct gcgattgggg agattgatga cgagactttc
    21181 agccctgctg acttgtcaga tattagtagt aaggaatttt tgagcggagc gatttccgat
    21241 tataatcgcc tttttcagac taattttagt atcaatggca atgagtttca aaactattac
    21301 cgtgatttag ctaagcgagt taagtctgga gaagtggatt tgctgattgt cgttggtatg
    21361 tttttgactg gttttgatgc accaaccttg aatactcttt ttgtggataa aaacttgcgt
    21421 tatcatgggc ttattcaggc tttttctcgg acgaatcgga tttataatgc gacaaagaca
    21481 tttggaaata ttgtaacttt ccgtgatttg gagaaggcta cgacggatgc tattaagttg
    21541 ttcgggaaga cggagacggc tgatattctg ttagagcgct cttacgagga ctacatgaat
    21601 ggctacattg aggctggtca agagcaaaaa ggatatttgg aagtcgtaaa agaattgcag
    21661 gagagatttc cagatccaac gactattatc aaagaaagtg ataagaaaga atttgtgacc
    21721 ttgtttggtc agttcttgcg cttggataat atcttgcaga actatgatga tttcatgagt
    21781 ttgcaggctt tgcaagagtt agatgttaca gatatagagg ctttggcaga tttcaaagga
    21841 cgttttcatt tggatgacga agcagttgca gtactctctc aactggacat cccaagtgtt
    21901 cgtgagattc aagattatcg ctccgcttac aatgatatca agtcttggta tgacaatgag
    21961 cggcgtaatc agcagaataa cgattccgaa atcgactggg atgcggttgt ctttgaagtg
    22021 gagttgttga aatcacagga aatcaatctg gactatattc tggaattgat ttttgaaacc
    22081 aaccaaaagg tatctgacaa ggatcaactc attgaagaaa ttacacgaac tatccgtgct
    22141 agtctgggtc agagagctaa ggaaagtttg atcgtggatt ttatcaatgc cagtgacttg
    22201 gacagttttt ctgagaagtc agatatcttg gagcaatttt atacatttgc ccgtcaaaaa
    22261 caaaaagaag cagtggctaa tttgattgag actgagggat tgaatgtaga gagtgctagc
    22321 cgctatattc agatgtcact caaacgagag tatgccagtg aaaatggtaa tgctctcaat
    22381 gaagcacttc ctaagatgag tccgctcaat cctcaatatc gtaccaaaaa gcagatggtg
    22441 tttgaaaaaa ttgtggattt ggtggagata tttaagggga ttggtggaga aatttaatta
    22501 ttattatttc ttctagatat agaagagata aactttaaat tagagcttga aattttaaga
    22561 aatattaagg catcatatca gtagtataaa aagctgactt ataatttatt tggaaacgac
    22621 agttaatcct aaaatacgat gcttgatatg gaggaggctt aaacttggaa aataaaaagg
    22681 atttaattca aaccttagcc tactaccaat tctcactaga aaaccaatac ttggatagaa
    22741 aatcagcacg aaagaagccg caagaattac tcaagcatct gattgctttt gccaatgcgg
    22801 acggcggtca gttggttatt ggtattgaag atgagaagca ggacaatatt atcactggtt
    22861 tcaaggatgg cagagcttat cccatagacg atttcaaaaa aattgaccat gagatgcggg
    22921 agactcctct ggatttgtct ttagaggaaa tccctgtgct aaatcataag ggagaagatg
    22981 acctgatttt ggttatttct gttgaattat cgtcgaaccg agtgattgct gcgcctaatg
    23041 atgaggttta tctgcgtcag ggcgatgaat cggttaaatt aagctatgag caacgtactc
    23101 agcttagcta tgataagggc caacgtttct ttgaagatga agtggtacct gatgcgacct
    23161 tggaagatat tgatgatggg ttagtccagg acttcaaaaa tcggtttgat atttcagagc
    23221 gctccatgga agaagttctt aaagcaagac gattcttggt taatggtaaa ttaactaagg
    23281 cagcgattct actctttgcc aaatatccat cagcgttttt tccacaagct cgtgttcgtt
    23341 ttcaacggtt tgacgggacg gatatgggaa caggcagtag ctttaatgtt attaaagaag
    23401 taacttttga tgatgctctg cccaccttaa ttatcaaagt gcgagatttt atccgtactc
    23461 agctgcgtga atttcagtac ttagacgata atgggcaatt ccagattttg cctgagtatc
    23521 ctgaatttgc ttggtttgag ggtgttgtca atgcggtgac tcaccgtgat tactctgtct
    23581 atggggatca cattcgtgta ctcatgtttg atgatagact ggagattcat agcccaggga
    23641 aattaccaaa tatcgttacc gttgacaata tcaagcatga atgtttttct agaaatcctc
    23701 ggattgcgag aaccctgact gaatttggat gggttcgtga gatgaatgaa ggagtgaagc
    23761 gtatctattc tgagatggaa tcagcttttc ttcatgaacc taaatattta gaaccaggta
    23821 ataaggtagt tttgaccctt gaaaataaca tcgtgagtcg acatctccga acacgagata
    23881 gtttggaaaa acaattttct gattttggaa atctgactgc agatgaacaa gctatcgttc
    23941 actacatgta taattctggc gataaaatga caacagcaaa ggcgattgag ttgacaggga
    24001 gaagtcgttc gtttgttgtc aaaatgctac atcatcttcg tgatttagaa atcatcactt
    24061 ggtttggttc aagtaaaaat gaccgtaatc aatattatct tttagttgat aaatgattgc
    24121 agccaggata cttattagta ataagaatac agtagaatac agaaaaagtg gtgttccata
    24181 aaatattgat caccactttt gattatagaa gtttaaataa agtggatatt tgtatatagt
    24241 tcacaatata tacctcaaat acaataagaa atagtggtta tatttttctg ttattgtaga
    24301 tatttaaaaa tagttgataa gtgattacat ttagcatctc tcaactgata aattccgaaa
    24361 acatacttat ttttagtaaa ctaatggcaa gtttgcaaat tgctttatat tgctaagtca
    24421 ctattgattt gttataatct tgttatacat aaggataacg caattaagga gactataatg
    24481 gctacattaa taagagatag acagtataat tttagagtaa atacggaaat gatggaagaa
    24541 gcaaagcgta ttttagaagc taaaaatatt agtgttccag atgctcttaa tctatttgtt
    24601 gaacgggtgg tggaagaaaa agatttacct attaaaactg cagaacaaat tagagctgaa
    24661 tcatttttaa atgaactgat atcagagctt gatgaagggt atcaagatat tttagcagga
    24721 cgtacgaagc cagctaatga ggtattttca aaatatggct tatgatatct atatttcaaa
    24781 taaggcagaa caagatttag atgaaatcta taactactat ttaacagaat tttcgcactc
    24841 aagcgctcaa aaagttattg aatctttgca gtcagctatt tctattcttg agatatcccc
    24901 tgaaggttat gttgattttg acgatcgtgt aggacgtaaa ctatttcctg aaggccagct
    24961 aaggatgatt cctagtaagc atttcatagt attttattta attcgtcagt caagggtaga
    25021 tattcttcgt attagaagta ctaaaactga ttatttaaat gatttagaga atctttttaa
    25081 caatatcctt taatgataga gtaagtattg ttttttatgt aactatttaa tcatgctctg
    25141 ttatgacggg atgatagtat aaagtggata tataaaagca aagtaaatac gagattttct
    25201 caactacata agctccgaaa actgagtttt ggtaatctaa tggtaatcta ttatttgtag
    25261 gattgggtta aaagtgctta tatttaatga aaatgagttt tgaaagcttg atttgataag
    25321 cttttacaga tatttggttt ttgtcaccca aaaccaggtc ttaagaaagc tcgtaaagct
    25381 agtcagttct caaaacgtta agaaccagct acaatacagc agaacaatac ttcatgggtt
    25441 accatggggt attttctttt ttgaaagaac tggcgacgca attgacgtag tcgttgcggc
    25501 tttagtcgct tacgaatacg gctgcaaagg agacgcagtc tccgtgcctc aaaacgttaa
    25561 tatatcgcat tatatcaacg tttcaaagca ctcaagagtt tacctcatgg gtgttttttc
    25621 tgtgctttct acgaaaatgg ctctataatt tggctcaatg tcaactgcag tgggtgactg
    25681 atagctaagc acgagaagag ataaattttg tctcttcttt tgtgatgttt aaagcattgg
    25741 gaatcttgac tttgaagttc ttaaagttcc taaatccaaa ggcttgctct ttcatgtcct
    25801 taatagtctt gttagtgggc tccaatttag cattggaata aggcatttgt gatgtagggt
    25861 ttgtatttca aaaagatttt gaggacggtt aaaacgtgat gattgaccaa gcttaaagct
    25921 cttcaatcag cccgaaaaac tcggttaccc actttttgaa aatgaaagag caagagctgg
    25981 taaaggtcgt ggtaattcca cagctcatct gagaaatcaa gtattttctg acttaccttt
    26041 tttgagtatt aaggtttgct taaaggttcg tgactagaag cgctgatcag acagtttatg
    26101 actgtccttt tggagcagtc atcaatgata ttttatggtt cgataaagca gaaatggctg
    26161 ctcaaagccc ttcataatgg ctatcaattc tggcggtcat caaagctcga cccaggtgct
    26221 gaatgatgtg aaagtaatcc catacaatgc tatcaaacac ttattgtcaa tcaaaagagg
    26281 ttgtctgttc cagcctcttt atactgtgac tataagctgc tctcatcggt cgaggataac
    26341 gaggtcattg aatactcgcg ctccactttt ccgagcggga gttcaatcaa aaggttactt
    26401 tttcttattt ggttggcctg taaatggatc aatggtctca aatgatgtca gttggtttgc
    26461 taccctatct tcctatagtg atttgaaata tatttggcta tcgtttttag atttttacca
    26521 gctgtgtctc cataatagcc catataccaa aatttctgat gcctatgttt atgcttaagg
    26581 ttggtgtctt tgtcaaaaat gattaggctg ctcttatact tttaagtatc tcataaagct
    26641 ggcaacactt cgtttaggaa aaagacttac taatgcatag atgtagtcgg aacatgtatt
    26701 cgctttgtga tgataagctc ttagcattcc acatatttgg tatgatgttc ctatatctac
    26761 tttgtaacgc ctatagataa aaagaggaaa agaccttgat gaatgaactg atcctcgctt
    26821 gttagagttt ttggctaacg gttggggtgc aattcaaaaa aatcaaggtc ttgttatttc
    26881 attaaagctt ggctgtactt atgttaatct ggcagatgct cataggctag gcagatagtg
    26941 tagcttttgg tgcctccttc tttgaggata atgtcaccaa actggttgtg gtgaatagca
    27001 tcaggcaggg tttgtgcttc catagcgatc ccctcacgag ccagtccctc cttgccctga
    27061 tctcttccaa aatacaagcc atcttggata ctgtccatgg tataaatgac gagtgcgttt
    27121 cggtcagagt agatgctgat ttggtcatgg ctgacgctgt cttgtaagac agcaataggt
    27181 ttggttgttc caatagcctg ctgatcaatt tcaaaggcag tatcaaagcc attattttcg
    27241 acaatagcag gatagaggga ctttattgat ctaaaatcat agaccgtctg gtcaactgct
    27301 agcttttgac ctgttgggat tagctcatta tctgtttcaa tcctatgtga tgctgcgatg
    27361 tataggttgt gattggttaa gtcttgtgtt tgccctaaat taaaataaac atggttggtt
    27421 ggattgaata ggctagtgcc tctcatgcta tgagccttaa agtgaatgct taaacgatta
    27481 tggttgtcta gacggtaggt aatgcttacg gtcaggtcac ctgggaaatg gtcatctgct
    27541 tctaaaatat cccttttaaa ggttacttca aggtaatcaa ctgtttggcg ggtatcataa
    27601 ggccaatgaa gcttatgaaa gcccttgaag cctccatgca ggcaatgccc attttcattg
    27661 gtgtcaacac aaaccctttg ctgctctagc tgaaagcttc ctctctttat gcgacctgct
    27721 actcggccaa tggtttgccc tgcacaaaga ggatttttta ggtagtcact tggtcggtca
    27781 tgtcccaaaa tgatattttt tggctgcttt tcatttgaca ctagaaaggc ctgtagagtg
    27841 gctcctagtg tcaataggtg agcctcaaca ccgttagtat taatcagtct tagctgggtg
    27901 actggcactt gatcgatgta ttcaatgatg tcttgataaa tgttcacagt ttgtttctcc
    27961 tattagtata ggtgtatgaa ttaagggagg ctgactactt gctgtggtag ctgtcttgag
    28021 ggactagctg ccacttgctt tatcgtcata tccttttgga tgcttggtat gccaggccca
    28081 ggctgatgcg attatcttgt caatatcgtc atagcttggc ttccaattga gaaccttgcg
    28141 tgctttttct gatgacgcaa ttaaggtgtc tggatcaccg ggacgtcttg cagctttttt
    28201 ggctggtatg gcttgtcctg ttacccgacg agcggcttca agcagttgac gattggaaaa
    28261 gcctgtttga gaccctagat taaagacctg tgatggtttg ccctgacgca ggtatgccat
    28321 cgctaaaatg tgtgcatcag ctaaatcgat aggatggacg taatctcgaa cgttagtacc
    28381 atctggtgtg tcataatcat caccaaaaat catcacctgc tcacgcactc cctgtgcagt
    28441 ctgtaggata atgggtaata aatgtgtttc tggctcgtgg tcttcaccga tggagccatc
    28501 tggctttgct ccggcaacat tgaagtagcg aagggccaca aatgtgatgc cataggcttt
    28561 gtcggcccag gtcattatcg tttccatcat aagcttgctt tggccataag gattgattgg
    28621 gcatttaggc gctgactcta agatggggac tgtttttgga atgccataga cggctgctgt
    28681 tgatgaaaag acaatgcgct taaccttggc ttctctcatg acctcaagca gcttaatcat
    28741 acctgctgtg ttattgtcaa agtatttcag agggtctgcc attgattctg cgaccaagga
    28801 agaggcagca aagtgaatca cagtgtctat gtctggattg tccctaaaga cttgacgcat
    28861 aaaggctttg tctgctaagt ctcctttgta aaacagagcc tctgggtgaa cggctttacg
    28921 gtgccctgtc accaagctat caacaacaat gactttttct tctctctgtg atattagcca
    28981 gtccactgta tgtgatccaa tgtagcctgc accgcctaaa actagaacag tcattttttc
    29041 ctcctattct tcaattgctt caatgccaat gctcttaaga aaacgcataa aggctgcttg
    29101 accttcttga tcacgtttgt agacgccagc gtcctcaagg acacgaacaa agacagagcc
    29161 gacctcttct tggataatgt catcaacagt tatcgctgag agatctggtc gtaatgtgat
    29221 ctgatcagcc cagtccttgt ggtagtctgc gatttgattg gcttgattga ggatatattt
    29281 tttgacctca accaattcct ctttgaggcg cggtggtaaa atagctagcc ccataacctc
    29341 aataaggccg atgttttctt tcttaatgtg ttgcacatcg gcatgtgggt ggtaaacacc
    29401 gtctggaaat tgctcagagg tatggttatc acgtagaacc aagtctaatt caaactgccc
    29461 ttcttttttt ctggcaatag gtgtgatggt atggtgaggc tcttggttgg tataagcgac
    29521 gatatcaaca ctgtcgtcag aataatgacg ccaagccagt cgaatcgtgt ctgctaattg
    29581 aactagctga tctttgttgc tgctgcgcag tcggataact gacataggcc agttgagagt
    29641 ggcagcctgt atgtctggaa atcctttaaa ggtaaagcgt ttgtcttgtt ttgcgatttc
    29701 catcggaaaa acgtgccgac cggcctgata atggttgtgg gtcaaaatag agccgccaac
    29761 aataggcaga tcagcattag agccgacaaa atagtctggc aggatatcaa caatatcaag
    29821 gagctgtcta aaggtgcttg tactgattgt cattggcaca tgctcagtat taaaaataat
    29881 actgtgctca ttaaaataag cgtagggtga atactggaat ccccaagcct cattgcctaa
    29941 gctcatacgg ataatgcgat gattagctcg ggctgggtgg ttaatccgtc cttgataacc
    30001 ttcgttttcc atacaaagct ggcattttgg ataagaggat gccttagcct tcttagcggc
    30061 tgcaatggcc ttagggtcct tttcaggctt tgataggtta atggtaatag ccatatcacc
    30121 atattgagaa ggcactgtaa aggagatgtt tttggcaatt gctgctgttt tgatgtagtc
    30181 atttagctga ctaagctggt aaaaatctga gatagcctgt tgaggagatt gtgcataggt
    30241 atcccagaag cgacgattaa ccacacttgg aataggggtt atcatgttca ttaattcagc
    30301 tcctaagcag tccttttctt caggaagcct gcctattttg ccattttcag cagctagctc
    30361 aaccaatgct tctttgagag ctattaaggc tgttaaggag gtttcttgcc agacatggtt
    30421 ctcaccaacc aatgctaaaa cccgattgcg gatataaata gcgtcctctg atgtgtagtc
    30481 gctgtgttca atcaccttcc ttacaaaggt gtctattaag cttgccatat cttatttcct
    30541 tgaaagtagt cgtgctccct gagcaatctc agccagataa aaggctggag catagccaat
    30601 gaccttagta taggccttgc caactgtttc gataaagcta tctaccttat ccttagccac
    30661 gatagcaatg ccacagcctc caaagcctgc tcctgtcatg cgagccccta ggaccccttc
    30721 ttgctcccaa gcggtgtgga ccagtgtgtc cagctcaggg cctgtgacct cataatcatg
    30781 ctccaaggat acatgagaag cattcatcag acgaccaaat tgctccaatg ctcctgcttc
    30841 aagggcctgt cttgcttgga gtgttcgttg attttccaaa acagcgtggc gagcgcgttt
    30901 gagacgttta ccatctttga taaggtagct gtactcatca aagcgctgag cgtctaattc
    30961 ccccagtgct ttaatatcca gaagggcatt taattcctca agggcttgtt cacactctgc
    31021 tcggcgttca ttatactttg aatcggctag ctctcggcgc ttgttggtat tcatgatgac
    31081 aatcacgtga tcaccaaggt caagcggaac agcctcatag gctaaggtgt tggtatcaag
    31141 gtatagagcc tgcttatcag ctcccatgcc tatggcaaat tggtccatga tacctgaatt
    31201 caccccgata aagtgatttt cagcttgctg accgatttta atcagatcta accgttccac
    31261 atcaagccca aacagctctt gtgccacaat acctgtcaaa agctccagtg atgccgagga
    31321 ggacagacca gacccatttg gaatgttgcc aaaaacgtaa agctcaaagc ccgtatcaat
    31381 aaggtgccca gctttttgca aaaaggagag aactccctta gggtaattag cccaaaggtc
    31441 agcctgatca aaggtcagct gatttaagtc aacctcaata atcccagcct cttcaaaatt
    31501 tgctgagaaa aagcgcagct gctgatcctc acgcttgcgg gccagcccat aggttcccag
    31561 actgatagca gctggaaaga catgtccacc attgtaatca gtgtgctcac caatgaggtt
    31621 gatgcgaccc ggtgagaaaa agacagcatc tggctccttg ccaaaaacgt cagtaaagct
    31681 ttgcttaagt tgcgcgatat ccattagcgg ctcctttaac gatgttgata gcttgatttt
    31741 acgcttcgct aagctgctcg tcaacatttt tactaaaatt ttactaaata ttgcttttga
    31801 aaatgcttgt gatatactag aagaaatcag aaagaaggtt tgatatggta acgcttaagg
    31861 atattgcagc tctggcaaag gtttctcctg caactgtttc tagagtttta aataaggacc
    31921 aaagcttgtc tgttggtcaa gagacaaagc accgcattct cacaattgct gatgagctgg
    31981 gctaccaaaa gcatttaaaa gcgacgaata gccctaaatc aaagctaaaa atagctattg
    32041 ttcaatggta ttctcaagaa gaggagctca atgacctcta ctattatgcg atccgcattg
    32101 gcattgaaaa aagagcttat gaattggatt atgatattgt tcgttatttc aacaatgaca
    32161 ttttgagggt ttcagatgac catgccggga ttattgctat tggaaagttt agcgcttgtc
    32221 aaatcaagga gcttgaagcc ttatcccagc atttggtgtt tgttgatagt gacacgcttg
    32281 aattgggcca cccctgtgtc acaactgact ttgacaatgc agtgctgaaa gttcttgatt
    32341 attttatgag caaagggatt tatagcattg gcatgattgc tggtgaggaa aagacaactg
    32401 acggtagaga agctttagtg gaccagcgct ttcgcaccta taaaaattat gcctctgagc
    32461 atgggattta tcagccgagg tatgtctata tcggtccttt ttcagcacaa tctggctatg
    32521 agcttatgac acaggcaatt gaggagctag gtgatgattt gcctaaagca ttttttattg
    32581 ctaatgatac ccttgcaata ggtgctctaa gagctctcca agaaagaggg cttgcggtgc
    32641 ctgagcgtgt tgagcttatc tcctttaacg atactccttt aacaagacag gtctttcctg
    32701 cgctttctag tgtgactgta tttacagagg atatgggacg tatggctgtt gatgtgctta
    32761 ataggaatat ccttaaccca gaacgtgtca agaccatgac gatattggcg acagagttga
    32821 ccttaagaga cagcacgatt ggttaggcat tgagctagct gggtaaagag ttcagtaaaa
    32881 tgaaacacta gacggcaacc atattagaag ctttaagact gactaatgac atagtgagta
    32941 ttatttgacg atgttttgaa taatgattat aatagtcgtg aaatataata gaaaatgtag
    33001 gatatcataa atgaaaaaag ccctattgat tgttaaccct agctcaggtg gtgagaaagc
    33061 caaggaatat gaagccttag cctatgataa actagcttcg tattttgatg atgttgacgt
    33121 taagcacact gaaaaaggag gagatgccaa acggtttgct catgaggcag cccagcagcg
    33181 gctggacagt gtctttgtca tgggaggtga tggaacagtc aatgaaggga tcagcgggct
    33241 tgcagagcag gactatcgcc ctaagtttgg cttttttcct ctaggaacag tcaatgattt
    33301 ggcacgtgcc ttgggcatgt cgttagaccc agaggaagcg attaatcaga taagctttga
    33361 gacaaccagt cctctggata ttggtaaggt caacgatgct tactttatga atgttgttgc
    33421 catagggacg ctcccagagg cgatcaatga tgttgcccct gaggagaaga cgacctttgg
    33481 gaaaatggct tattttatgt caggctttaa gcagctgatc aaaaataaaa gctatacctt
    33541 ccagctagat attgatggca aaacaaaaga aatcaacagc acaacactct tgattggctt
    33601 gaccaattca atcgggggct ttgagcggat tttgccagag gcacgtgtgg acgatggttt
    33661 gctgcacctt atctatctga aggatagcaa tctattagaa acggtgaagg cccttcctag
    33721 cctattgaag ggagttgagg cttcagatca aacacttggc tatcaaacct tcaaggaggc
    33781 cactattgcc atgaaggaag gacagctatc tatcaatgtg gacggtgatg agggtgaggc
    33841 cttaccaatc actgtcaagg tacttcctca gcacctgcag gtatatcgtt aatctgaata
    33901 atgaagttag tcattcttat acggtggagg atatgaccta gtgtgattag caatggtagc
    33961 cttaacaagc gtgtccgtcg tagctgttaa tcagaccttc atatcagcgt ggctatacca
    34021 tttgccttta gcatgatacg ttaacagcag caggcttagt agagagagga tttggtttga
    34081 atcctctttt ttgctgcctg gggcttggct gatttggctg ttcagtcatc atcaaaatgc
    34141 tttgcttgct gtggtatgag cattgttgtt gacttggcgg gggttatttg ataggatagc
    34201 agcacaaaaa tcttaactag ttaagtttta ttaaaaagca tagacaatca catcatcact
    34261 gcggcgacag ccttgagagt agctaaaatg gctactaact attatcttag atcggctgtt
    34321 gcctctagat gtctgttcat ctgatgcttt ttgttgtggc atgtagcccc ttaggtggac
    34381 tttgaaaact tagctttaaa gcttaggcat cataggctaa gagagattgc tgctgttcct
    34441 atcacctcag aaagggtatc aaggggatat ttcccattaa aactaggcta gttaatcaaa
    34501 ataaaggagc ttttttatga agaaacagtc attgaaaaaa gtcagtcttt taacggttac
    34561 tgttatatct agcttggcct tggcagccaa tgccaatacc tatacgactt atgccagaga
    34621 caacgttgtc actgcgacgt cgcaagcggc tgagggtttt gattttgttg ccacgatact
    34681 tgatagcaac ggtcgtgctc ttgaaggaaa aacagttgtc ttgttagaca cgacagctaa
    34741 tcccgctaag caggtagctt ctgctgtctc taacagcaat ggtcaggcta tttttactca
    34801 attaccctta aacattaatt tgagtgtttc tgttgacggg gaaaccaagg gctatacagt
    34861 gagaaccagt cttgctggat ctaaagaggc agcaagcttt gtcgctaagg gagcagggac
    34921 aaaggagcct ctttatagta aaaatgtcat tgatattacg gtccgaaatc aagatagtga
    34981 gcccttagaa gggcaaacag tcaccctaaa aatacgtcag ggtcaactgg tgggaagtct
    35041 tgtctcagat aaaaatggaa aggtaacctt caaggatcgt ttgttggacg gaacctttta
    35101 tcattatgag cttaatggta agtatatagg gcaggtcatg acaaaaatgt ctgttaatgc
    35161 ttaccttgat acctcatcaa gctcgtcatc aggtacgtca cctcagtcca aggacactcc
    35221 taagcaggag gatggaaagt caagtccgct agaggaaggc tttcattttg ttgtcactgc
    35281 cctagataaa gaggataggg ttgttgcagg caaggaggta agcttgactg ctctgataga
    35341 cggtgctaag acgacaattg cttcagcaaa gacaaatgct gatggtcaag cagtctttac
    35401 caaactacca ctatcacgta atatcagtgt ctcaattgat ggtaagctac agggctatac
    35461 tgttcgcacg agtgagtcta atgagcataa ggctgctgct ttttatgtcg acggtaaagg
    35521 aacaaagcct gttgtttact ctaagacacc agccatagta actgtttatg atgccaatgg
    35581 aaataagttg gcagggcaag aggttgtgct gaaaaatcga tacggagcta tcagggcaat
    35641 aggcaaaact gatcaatcag gtaaggcaac ctttgtgaat cagctcatgg acggtatgtt
    35701 ttatgagatt gttatcaacg gggtcaagat acctaaaaaa gcctctaccg gtagtgatgt
    35761 cagcggcttt ttaaccaaag ctcaaatcag aaccgataat aaactcagcg agtctgagcg
    35821 ccattctaaa gacacaaagc ccttaggcaa ggagccaaag gatcctgaaa aggataagaa
    35881 tgtcgctaag ccagaaacca agtcctcgtc aaaccgtaat gtagccccta aagaaggtaa
    35941 aaaagagact aaggctttgc caagatctgg tgaatcagca gcgccgatgg tagcgttcat
    36001 gggagttcta ttaataggcc ttgcagctgt catcggtctt gtgacaaaac gtcgctctag
    36061 ctaaaaccaa ataagtaaaa acgtcttgca gctatcaagg cgtttttttg acggttaagt
    36121 gattgttcag cgccgttcta caatctaaaa aaagaaggct aaatcttttt taaacgtatc
    36181 atgcaacagt aagataacag acagtgaggt catgcgtcac agaccacagt ttatcataga
    36241 gctatggctt cttataaagg ttaagcaggt taggggctga ttaagccatc gttttaatgg
    36301 cttttatttt ttattaaaaa atttgacaaa tacatctaaa gctgttaaaa ttaaccggtt
    36361 cataactggt taatgagcaa aggagattat atgaaaagaa aatggataca tttaacactg
    36421 ttgcttgctc ttttttcagg tcttgttgcc tgtagcaagc ccaaggagca aagcaagcag
    36481 tcaagaggca tgacgatcgt cactagcttt tatcctattt acgccatgac aaaggcggta
    36541 tctggtgagc taaacgatgt tcggatgatt cagtcagggg caggtattca ttcctttgag
    36601 ccatctgtaa atgacgttgc tgccatttac gatgctgatt tatttgttta tcactctcac
    36661 accctagagg cctgggctga tgatttggat cctaatttga agaaatcaaa ggttgctgtt
    36721 tttgaagctt ccaaatcttt aaccttagat cgtgttactg gtttggagga tattgaggtg
    36781 acagatggca ttgaccctgc taccctgtat gatcctcata cctggacaga tcctatttta
    36841 gcaggtgaag aagcactcgc tattgctaag gagctcagtc gtttagatcc taagcatgag
    36901 gccatttaca ctgagaatgc tcaagcattc caaaaggaag caaaagagct ggctgatgag
    36961 tacactaaaa agtttaaaaa gacatcatct aaaacctttg tcacacagca cacagccttt
    37021 tcttatctag caaaacgctt tggcttaaag cagttaggta tttctggtat ttcgccagag
    37081 caagagccta ctcctcgcca actaactgaa attcaagact ttgttaaaga atataaggta
    37141 aaaacgattt ttgcagagga taatgttaat cctaaaattg ctaaggcgat agctaaaaca
    37201 gcaggagcaa aggtcaagct gctcagtcca ctagaggcag cgcccaaaaa caacaagtcc
    37261 tatctagaca atttgagagc taatttggaa gctctttacc aaagcttaaa ataaagggag
    37321 atgaaaacgt gaaaaagaag catattgttt taggatcagc tgtggccatt ttattggcta
    37381 ctaatgctgc ttcatatcag tttggaatgc ataaggctct aaattcctca tctaaagata
    37441 atagcattgc ctatattgat tcaaaggatg gcaaaaaagc cctccccaaa gaaaaaacaa
    37501 tggatcaaat cagcgcagaa gaggggatct ctgcagagca aatcgttgtt aaaatcacag
    37561 atcaaggcta tgtaacctca catggtgatc atttccattt ctacaatggt aaggttccct
    37621 atgatgctat tcttagtgaa gagctattaa tgacggaccc caattatcag tttaaacagt
    37681 ctgatgttgt taacgagatt ctagatggct atattatcaa ggttgatggc aagtattatg
    37741 tttatctaaa gccaggaagc aagcgtaaaa atattcgtac caagcagcaa attgctgagc
    37801 aggttgaaaa gggaacaaag gaagctaagg aaaaaggctt ggctaaggtt gcccacttga
    37861 gtaaggcaga ggtggcagct gttaacgaag caagaagtca aggacgctat acaactgatg
    37921 atggctatat ctttagcccg acagatgtta ttggagacat gggagatgcc tttttagtgc
    37981 cccatggcag tcacttccac tatattccta aaaaggactt atccccaagt gagctagtag
    38041 cagcgcaggc ctattggaat aacaagcaag gcggaaaacc aagtgttatt ggcggtcagc
    38101 ctttaccagg tcaaggagat cagcctagac catatgatat tcctgttaac ccgattcacc
    38161 acccagctgg gaatttgccg tcagtaggag atccaagcct atcatttgca gataaaacct
    38221 ttggagaatt gttggatcaa ttgcatggct tggataagaa atacaggcac gtcaaggaag
    38281 atggtctcat ttttgagcca actcaggtga cccttgccaa tgcctttggc tatgttattc
    38341 ctcatggaga tcactaccat attattcctc gtgagcaatt gtcagccctt gaaataacct
    38401 tggctgatcg ttacctagca ggtcaaacgc agggcagtcc aatagctaag ccaaagccag
    38461 ctactcaaga ccagactgca aaagaggtta cacatcaatt ccttggccat cagattaagg
    38521 cttatggtaa aggcttagat ggcaagcctt atgacacgag tgatcattat gtctttagta
    38581 aggcatctat ttcctctgtt gataaggcag gcatcacagc taagcatgag gagcatttcc
    38641 attacatggg ctttggtgag ctagagcaag aggagcttga ccaggttgca caatggctgc
    38701 aggagcatgg tcaagcagat gagattgcaa gggcattagt tcaatcagac ggtaaagaca
    38761 tgtcctttga cgctaagcat gtcagtcgca aggtaaccaa tggcggtaag gttggttaca
    38821 tgatgacaaa agatggcaaa gagtatttct atgatcgtga gcatttagac ctaacacaaa
    38881 ttgcctttgc agagcaagag ctcatgctta aggataagca acactatatt tatgacattg
    38941 ttgatacagg cgttcagcca aagctagctg tagaggtatc cagcctaccg atgcatgctg
    39001 gtaatgcaac ctatgataca tggacatctt ttgtcattcc tcacatcgat catatccatg
    39061 ttgtacctta ttcatggcta actaaggatc agattgcgac catcaaatat gtcatgcagc
    39121 accctaatac tcgtcctgat gtttggtcta acccaaatca tgatgaagct ggaggagtca
    39181 ttgctaatgt cacaccagct gatcaacgta cttcaatgga aaactggcaa attattcact
    39241 ctgccgaaga ggtccaagca gctatcaagg caggtcggta cgcagctcca gatggctata
    39301 tttttgatcc taaggacgtt cttgctgaag gaacctttgt ttggcgtaat gattccttta
    39361 gcattcctag agttggtgga cgctctttaa gaaccattac taaagatgag ttatctcatg
    39421 atgaatggca aaaggttcaa gaattattag gcaataagac ctcagacgca gctgaaagca
    39481 ctattaagcc aaccaaagac caggaaccgt cagcgcaaga tactgccgca gatggcatag
    39541 agcagaccaa gtctttattt gacgatattc ctaattatgg tttagatcgg gcaactcttg
    39601 aacgtcagat caatcagtta gctgaaatag caggcattaa accggagtat cttattttcg
    39661 tgccagaggg tgtcaaattc tatgaccaaa aaggacacct aatgctttat gatgtgacaa
    39721 cattgcaaca aatcaaataa acactataaa atagctaagg catacaaatc acagcttatc
    39781 cccaaaaagc tattggtatg atgacctgtt cttacgcctc acagcctaag atcgcttagt
    39841 aggcttttgc ttgcagcaac agtcagagaa gctgacttga tcagcagctt agcacctcat
    39901 agcttttaaa gcattggatc tctgtaggct atatgtgggt tttggttcca agaaagtcta
    39961 tatgacctaa ggagggcagc acagaaagag tttttaccaa ttaacctcac acctaatagt
    40021 cctccagtca aaaccgccta gcctttaata gctagacctc ccctttaaag tggacagtga
    40081 aaaacaatca ctaaaaacga taaggggagt tttttggtgt ctaaaagggt taggaaaaag
    40141 gttagcagcc gtacaatt
//
LOCUS       DARYLJ010000015        39075 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYLJ010000015 DARYLJ010000000
VERSION     DARYLJ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39075
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            110..637
                     /locus_tag="TU746_000706"
     CDS             110..637
                     /locus_tag="TU746_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL0891071.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TU746_000707"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TU746_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL0891072.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TU746_000708"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TU746_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL0891073.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TU746_000709"
     CDS             2207..2839
                     /locus_tag="TU746_000709"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL0891074.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TU746_000710"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TU746_000710"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL0891075.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TU746_000711"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TU746_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL0891076.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TU746_000712"
     CDS             3914..4657
                     /locus_tag="TU746_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0891077.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TU746_000713"
     CDS             4767..5867
                     /locus_tag="TU746_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL0891078.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TU746_000714"
     CDS             6223..6930
                     /locus_tag="TU746_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0891079.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TU746_000715"
     CDS             7071..7787
                     /locus_tag="TU746_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0891080.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TU746_000716"
     CDS             8009..8854
                     /locus_tag="TU746_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0891081.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TU746_000717"
     CDS             9226..10071
                     /locus_tag="TU746_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL0891082.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TU746_000718"
     CDS             10149..11519
                     /locus_tag="TU746_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL0891083.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TU746_000719"
     CDS             11512..12576
                     /locus_tag="TU746_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL0891084.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TU746_000720"
     CDS             12577..13269
                     /locus_tag="TU746_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891085.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TU746_000721"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TU746_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL0891086.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TU746_000722"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TU746_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL0891087.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TU746_000723"
     CDS             complement(16695..17369)
                     /locus_tag="TU746_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL0891088.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TU746_000724"
     CDS             complement(17379..18755)
                     /locus_tag="TU746_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL0891089.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TU746_000725"
     CDS             complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TU746_000725"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL0891090.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKKPL"
     gene            20127..20684
                     /locus_tag="TU746_000726"
     CDS             20127..20684
                     /locus_tag="TU746_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL0891091.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20721..21614
                     /gene="htpX"
                     /locus_tag="TU746_000727"
     CDS             20721..21614
                     /gene="htpX"
                     /locus_tag="TU746_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL0891092.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21902..22435
                     /locus_tag="TU746_000728"
     CDS             21902..22435
                     /locus_tag="TU746_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL0891093.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22620..23306
                     /gene="covR"
                     /locus_tag="TU746_000729"
                     /gene_synonym="csrR"
     CDS             22620..23306
                     /gene="covR"
                     /locus_tag="TU746_000729"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL0891094.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23310..24800
                     /locus_tag="TU746_000730"
     CDS             23310..24800
                     /locus_tag="TU746_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL0891095.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24991..25485
                     /gene="nrdR"
                     /locus_tag="TU746_000731"
     CDS             24991..25485
                     /gene="nrdR"
                     /locus_tag="TU746_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL0891096.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25469..26632
                     /locus_tag="TU746_000732"
     CDS             25469..26632
                     /locus_tag="TU746_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL0891097.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26633..27541
                     /gene="dnaI"
                     /locus_tag="TU746_000733"
     CDS             26633..27541
                     /gene="dnaI"
                     /locus_tag="TU746_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL0891098.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27591..28901
                     /gene="der"
                     /locus_tag="TU746_000734"
     CDS             27591..28901
                     /gene="der"
                     /locus_tag="TU746_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL0891099.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29242..32334
                     /locus_tag="TU746_000735"
     CDS             29242..32334
                     /locus_tag="TU746_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0891100.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32538..33131
                     /locus_tag="TU746_000736"
     CDS             32538..33131
                     /locus_tag="TU746_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891101.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33175..34506
                     /locus_tag="TU746_000737"
     CDS             33175..34506
                     /locus_tag="TU746_000737"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL0891102.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34554..35036
                     /locus_tag="TU746_000738"
     CDS             34554..35036
                     /locus_tag="TU746_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0891103.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35145..36719
                     /gene="mltG"
                     /locus_tag="TU746_000739"
     CDS             35145..36719
                     /gene="mltG"
                     /locus_tag="TU746_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL0891104.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36792..37274
                     /gene="greA"
                     /locus_tag="TU746_000740"
     CDS             36792..37274
                     /gene="greA"
                     /locus_tag="TU746_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL0891105.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TU746_000741"
     CDS             complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TU746_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL0891106.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38518..38796)
                     /locus_tag="TU746_000742"
     CDS             complement(38518..38796)
                     /locus_tag="TU746_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL0891107.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
BASE COUNT        11290 a         7214 c         9221 g        11350 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt ttattaggaa taccggcttt tcgagggtac
    19321 ttgtttggcg tttccttttt cttttcgaca agagtgatat agcggccatc tccattagga
    19381 agttggtagg gctggtgatc aagcacctta gcaaaaagta gctgaagtgc ctttttagct
    19441 tcttctaatt cttggtccgc tgcttgtgcc tttaaagcaa tcagttttcc cttgattttt
    19501 aaaaaaggaa tggtcaactc agacagaatc tgcatgcggg caacagctct agcagttacc
    19561 aaatcaaatt ggccacgaaa ttgcttgtct tgtccaaaat cctctgccct accatgatag
    19621 aaatgtactc cctctaatcc tagctcttta gcaaggagct gaagaaaatg tatgcgctta
    19681 ttgagagaat caataatggt aacatcaagc tttggaaaca taattttcat aggaatgctt
    19741 gggaagcctg ctccagcccc aatatctaac agcctgagag gctcatttgg aatatatccc
    19801 tgtaaaagcg gagcaacaga gtcataaaag tgcttgagat agacttcatt ttcttcagtg
    19861 atggctgtta agttgatctt acggttccaa tcaaccaaaa gcttaaaata agtgtcgaat
    19921 tgttcttttt gatgatttgt cagagcaaat cctgcttgct ccaggacaag gtaaaaggct
    19981 tggggtgtca tatatatcct ctgtttttaa ttaattgcta ctattttagc ataaaatagc
    20041 agaaaactgc tgaaaagtcc cttcaatact tgctattaaa ctgaaaattg ctataattga
    20101 gacacaaaga ttaaaggaga attacaatgc caatgttttt agtaatagta gcccttatcg
    20161 gtgtgctggt tgtttggctg atggttagct ataatggcct ggttaaagct cgtatgcata
    20221 caaaagaagc ttggagtcag attgacgtgc agctaaagcg tcgcaatgac ttgattccaa
    20281 accttgttga gacggtcaaa ggctatgcta atcatgaaga gaaaacctta gaaaagatta
    20341 ctagtcttag atcacgtgtg gctgatgcta ctacaccgca ggccacaatg gcagcctcca
    20401 atgaattgag caagcaggtc actagcctct ttgcagttgc agagagctat ccagacttaa
    20461 aggccaatag taatttccta aaattgcaag aggaattaac caatacagaa aataaaattt
    20521 cttattcgcg tcaattattt aatacaacaa catcgcatta taaccttaag ctagaaagct
    20581 ttccgagcaa tcttgtggct aaattgtttg gcttcaagcc aagtgagttt ttacaggttc
    20641 ctgaagctga aaaagaggtt ccaaaggtag actttaccgt ctagtctaat gcggctaatc
    20701 aaggtcagaa gaggacatca atgctttatc aacaaatttc acaaaataaa cgacgaactg
    20761 ttatcctgct ttttgccttt tttgtcttac tggtagtgat tggcgctgct gctgggtatt
    20821 tactggctga cagctaccag ctgggggctg cttttgctct gattattggt gctatttatg
    20881 cctttagcat gatttttcag tcaaccagcc tcgttatggg aatgaataag gctaaggaaa
    20941 tcacagtaaa cgatgctcct gatttctttc atattgttga ggatatggct ctggttgctc
    21001 agattccaat gccaagagta tttatcattg atgatccctc actaaacgcc tttgccacag
    21061 gctccagccc tcaaaatgca gctgttgcgg caaccactgg tctactaaag gtgatgaatc
    21121 gtgaggagtt agaagcagtg attgggcatg aagtcagcca tattcgtaat tatgatattc
    21181 ggatatccac tattgcagtt gctttagcta gtgctgtcac actgatttcc agcattgggg
    21241 ggcgtatgat gtggtatagc ggtggcagga gacgtgataa cgatcgcaac gataatggct
    21301 ttggcgctat tatgctgatt ttctcaatct tgtcactgat cttggctcct cttgcggcct
    21361 ctctggttca attagccatt tctcgtcaaa gagagtatct ggcagatgcc agctctgtcg
    21421 cgttaaccag aaatccagag ggcatgatta gggctctaca aaagctaagc aattcacagc
    21481 ctatgactca tccagtagat gatgctagcg cagccttata catcaatgag cctagaaaaa
    21541 aagaaaagct tagcgcttta tttagtaccc atccgccgat tgaagataga attgaacgct
    21601 tgaagcatat gtgagagctt gagactagct cagctctcat ttttactagc cataatgttc
    21661 agaaaacatc attaattaat tgttttgacc cggacatttt ttaagacttt tatggaaatt
    21721 tgggctattt tcataggggt tttatggtta aacatttgat tgttggcttg tcaatactta
    21781 tttgtatcca gacttaatgt taaaaaaagt tatgaatttg tcataaagct attgacaaat
    21841 tcttgatatc atagtaaaaa tagattagag ttttattagg aagtgtttta taggagaaag
    21901 catgttatct gtttcagata ttagaaagcg accggaaggc attcgctttg agagagagta
    21961 cgatgttaag gaagcgctgc ttatacgtga tccgcaggtt atagatatta ataacgtcag
    22021 agcttcgggg agagctcagt ttgatgacgg cttgtatcta ttagagtatc agctgggcta
    22081 tcagattacc ctgccctcga gccgttccat ggcgcctgtt gtcttagatg agatgcagac
    22141 ggttcaggag ctgtttatcg aggaagcaga tgtggcaagt aagcaggaaa tggttgatga
    22201 aaaccttgtc ttagtcttat cagaggatca gcttgacctt gaagagagta ttattgacaa
    22261 tattttgttg gcgattccct tgcaggtatt gacagaggct gaaaaggagt cacaaatctt
    22321 gccgacaggg gaggattggg cagtcttaac tgaggagcaa taccaggccc agcagaagga
    22381 aaaagcaaaa gacaacagtc cttttgcggg cttacagggt ctttttgatg agtaaaaata
    22441 aaaattaaag atgtctgtat tttttatttg aaaaaagaac agttgtctgg tatactttat
    22501 aaatatacgg catattagtc attttgatga ctaaatagca atacttgatt aatacaaaat
    22561 ggatgaatct tgtacatagc tgataagggg ctgtgataca ggaagtaagg attggtgtaa
    22621 tgacaaagaa aattttaatt atcgaagatg aaaagaatct tgcaagattt gtttcgcttg
    22681 agctacagca tgagggttac gaggtgaccg tcgaggttaa tggtcgtgag ggcttggaga
    22741 cagccctaga gaaggacttt gacttaatcc ttcttgattt gatgcttcct gagatggacg
    22801 gatttgaagt gacacgtcga ttgcaaacag aaaaaacgac ttacatcatg atgatgactg
    22861 cgcgtgactc tattatggac gttgtagctg gcttggatcg tggtgctgac gattacatcg
    22921 tgaagccatt tgccattgag gaattgctgg cgcgtattcg tgctatcttc cgtcgtcagg
    22981 acattgagtc agagaaaaag actcctagtc aaggcgttta ccgcgactta gtcttaaacc
    23041 ctcaaaaccg ctctgtcaat cgcggtgatg acgagatttc actgactaag cgtgaatatg
    23101 acctgcttaa tattttgatg acaaacatga atcgtgtcat gactcgtgag gagctcttgt
    23161 ctaacgtttg gaaatatgac gaggctgttg aaactaacgt tgttgatgtt tatattcgtt
    23221 accttcgtgg gaagatcgat atccctggga aagagtctta cattcaaact gttcgtggaa
    23281 tgggttatgt gattcgcgag aaataattga tggcaaagca gaaaaaatat aagaaaacgt
    23341 taccaaaacg tttatcgaat cttttgttcg ttctcttctt ttgcattttc tctgccttta
    23401 ccctactcgc ttatatttca acaaactact ttttgttgaa acgagaaaag caaactattt
    23461 ttcaggctgt taacattgtt agagttcgtc tctctgaggt ggactctaat tttacgttag
    23521 agaatttagc agaggttctc tataaaaatg acagaacgca tttaaagatt gatgacgcaa
    23581 atggtagtcg tattatcaga agtgaacgaa atatcaccaa cacgctcaat gccaatgagg
    23641 atatctatgt ctacaatgtt gataagcaaa tgatcttcac aacagatgac gaagaggcct
    23701 cgccaggctt aaatggaact attggtaagg taaccaagga ccacattgag gagcaataca
    23761 agggcttttc aatgactcag aaggtctact ctaataagac agggaagttt gtaggctatg
    23821 ttcaggtttt ccatgacttg gaaaactact acatgatcag agcacgcctc ttcttttggc
    23881 ttttggtggt tgagctcttt ggggttggtc tggcgtattt cattatctta attgtcacac
    23941 gcaacttctt gaagcctctg aacaatcttc atgatgtgat gcggacaatt tccaaaaatc
    24001 cagataatct gatgctgcgc tcgggtattt cctcgggtga tgaaattgag gaattgtccg
    24061 ttatttttga taaaatgctt gataagattg agacgcatac acgattgcaa tcaagattta
    24121 ttagtgacgt cagtcatgag ctgcgcacgc cagttgccat tatcaagggg catattggat
    24181 tattgcagcg ctggggcaag gacgatagtg ctattttaga tgaaagcctc actgcagctg
    24241 cgcaagaggt tgaccgaatg gctattatga tcaatgacat gcttgatatg atccgagtac
    24301 aggggtcctt tgaagggcat caaaatgata caactgtttt agagagctct attgagaccg
    24361 ttgttggtaa ttttagggtc ctgcgtgagg attttgattt tacctggtac tctgaaaatc
    24421 aaagaaccct agccaagatt tataaaaatc attttgagca ggctctgatg attttgatag
    24481 ataatgcggt caagtattct aggaaggaaa agaaaatcgt catagaatta gcggttaatg
    24541 ctagcaatga agctgtggtt aaggtcaaag acagaggtga ggggatctca gaagaggata
    24601 ttaagcatat ttttgagcgc ttctaccgca ccgataggtc cagaaatcga accagcaccc
    24661 aagcaggtct tgggattggc ttatccattt taaagcaaat tgttgatggc tatcatttac
    24721 atatggaggt tgagagtgag ctaaataaag ggtcggtctt tattttgcgg attcccttag
    24781 ctgatcatca aggctcatag ctgtatacct gcctgagtat ctagtagatg ctcaggcttt
    24841 tgactgttct aatgtgtggt gtgatgatga ggtgtttatc agggaaggag ggctcttgga
    24901 ggtaaacctg agtgcttgtc tattcttttg ttatccctaa aattatggta aaatagggta
    24961 ttagattaac gatagaattg gggtgtttgc gtgcgttgtc cgaaatgtaa ctataataag
    25021 tcaagtgttg ttgatagtag acaggcagaa gatggcaata cgattcgtcg ccgcagagaa
    25081 tgcgaaagct gtcacacgcg ctttacaacc tttgagcgct tagaagagct tccattacta
    25141 gtgatcaaaa aggacgggac tagggagcag ttttcaagag ataaaatctt aaatggtgtt
    25201 gttcaaagtg cccaaaagcg tccggtgtca agtactgaca ttgaaaatct catttctcgc
    25261 attgagcaga aggttcgtac agcctatgaa aatgaggtgt caagtactgt tattggcaat
    25321 ctggtgatgg aggaattagc agagcttgat gagattacct atgttcgttt tgctagtgtc
    25381 tataaaagct ttaaggattt agacgaaatc gaagagctct tacagcagat tactaatcgc
    25441 gttagaggaa aaaagaagag cagtgtagat gatgaagcct attgatacct tttcttatat
    25501 taagcataat caggttcaat acgattcaag cagcctgatt cagttgtatt ttcctattat
    25561 tggaaatgac gcagtggcag tttatcagta tttggttcac ttttttgatg atggctcagg
    25621 agcccacaaa tttagtgata ttttaaacca tctgcagttt ggaatgaagc gcctagagga
    25681 agccttggtg atgctgacag ctattgattt gctggtctta tatcagctgc cagatgctta
    25741 tttgataaaa ctacatcagc ccttgggcag ggaagccttt ttaaataacc caatttatcg
    25801 taggctttta gagcaaaaga ttggagatgt agcggttttg gagttgcaaa tggtgattcc
    25861 gaaccaggct agaaacatct caaagacctt ttcagatgtt tttggaatag actctcagga
    25921 gcttaagcag cctcagccat caaagataaa ttttgattta gatagctttc agcagctaat
    25981 gcggcgtgac ggtcttaggt ttgaggatca tcaaaaggac gttatcagtc tttacagtat
    26041 ttctgagcaa taccacctaa cctggtttga cacctatcag ctggctaagg caacagcagt
    26101 cggcggcagc attcgcccag agcgcatgct agtcaagaag cagcaagagg gcgctcaaaa
    26161 aacaagtgaa tcgttctcac cagctgagca ggttgttctt agagagtcta agcaggacac
    26221 gcctcttgtc tttttagaga agatcaaaaa agctaggcga gctagagtca caaaggacga
    26281 aaaggaattg ttgctgactc tagcccgcat gaatttcttg gacgaggtca tcaatattat
    26341 ggtattatat accttcaata agaccaagtc agctaatctt cacaagactt atctgatgaa
    26401 aatggcaaat gattttgctt accagcgggt tttaacagcg gaaactgcta ttatcaagac
    26461 acgcgccttt ggtgagcgta agcagcaggc aaagtcacag cagtccaatg tgcctaagtg
    26521 gagcaatccg gattatcaag aaaaaacaag tcaggaagaa caggcaaagc tagagcagtt
    26581 taagcaggct gccttaaaaa ggctggagaa cctaggaaag agtggtgact agatggaaaa
    26641 gatcgggaaa atggtagagc atttgggaca ggctagtcgt gtagctagtg ctgagctgat
    26701 tgaggctata cttgctgatc aggaggtggc tgagtttatc aaggctcacc agctatctca
    26761 ggcagaaata aagctgagtt tatcaaagtt caaccagttt ttagttgagc gccggaaata
    26821 ccagacaggt gatgagacct atattgctaa gggctatcag cccattttgg tcatgaacga
    26881 gggctatgca gatgtgtctt acctagagac aagagagctt gttgaagccc aaaggcaggc
    26941 agctattgca gatcggattc atttggttag tctgccaaga tcttatcgta gggtttcttt
    27001 gtcagctgtt gatgttaaca atgccagtcg tatgcaggtg ttttcagagc ttttggattt
    27061 tgttgagcag tatccagcgg cagagcaaaa gggtctctac ctttatggcg atatgggggt
    27121 cgggaaatcc tatctgatgg ctgctatggc acatgaattg tctgaaaaaa agggtgtatc
    27181 aacaactctt cttcattttc ctagctttac gattgatgtt aaaaatgcca tttcaaatgg
    27241 ctctgtcaaa gaagagattg atgccatcaa gcatgtccct gttttaattt tagatgatat
    27301 tggtgcagag caggcgacct catgggtgcg tgatgaggtg ctacaggtta ttttgcagca
    27361 tcgtatgcta gaggatttgc caaccttttt cacctctaat tacagctttg cagatttgga
    27421 gagaaaatgg gcaaagatca aaggaaatga tgagacctgg caggccaagc gtgttatgga
    27481 gcgtgtgcgt tatttagcac gtgaatgcca tttagaaggg gttaatcgcc gccagggcta
    27541 gctaaacgct agctcaagcg atggataatg agataaagaa aaggagaatc atggttttac
    27601 ctacagttgc cattgttgga cgtcctaatg ttggaaagtc cacgttattt aaccgaattg
    27661 caggagagcg tatttctata gttgaagacg tcgaaggggt tactcgcgac cgcatttaca
    27721 cgactggtga gtggcttaac cgccaatttt cattgattga cacaggtggt attgatgacg
    27781 ttgatgctcc ctttatggag caaatcaagc atcaggctca tattgcgatg gacgaggcag
    27841 atgttattgt ctttgtggtt tctggtaaag agggcgttac tgatgcagac gaatatgtct
    27901 ctaagctctt gtatcgtacc aacaagccag tgattttggt tgtcaacaag gtggacaatc
    27961 cagagatgcg aaacgatatt tatgattttt attctcttgg cttaggagat tccttcccgg
    28021 tatcatcagt tcatggtatt ggtacgggtg atgttttaga tgctatcatt gataacctgc
    28081 cgatagaaga gccagtagaa aacgacgatg tgattcgctt tagcctaatt ggacgtccaa
    28141 atgttggaaa atcaagcctc attaatgcga tcctaggaga agagcgtgtc attgccagtc
    28201 ctgttgctgg tacgactcgt gatgcgattg atacaagctt taccgatgaa tccggtcaag
    28261 cctataccat gattgatacc gcaggaatgc gtaagtccgg caaggtctat gaaaatactg
    28321 aaaaatactc agtgatgcgt gccatgcgtg ccattgaccg atcagatatt gtgttaatgg
    28381 ttattaatgc cgaggagggc attcgtgact atgataagcg gattgcaggc tttgcgcatg
    28441 aggcaggtaa gggcatgatt atcgttgtta ataagtggga caccatcgaa aaggataatc
    28501 atacagtagc taggtgggag gctgatattc gtgatcaatt tcaatttttg acctacgccc
    28561 ctattatctt tgtttctgcc gttacaaagc agcgcttaaa caggcttcct gagttgatta
    28621 agcgtatcag tgatagtcaa agccagcgga tctcgtcagc tattttaaac gatgtgatta
    28681 tggatgctat tgcgatcaac ccaaccccaa cggataaggg acggcgtcta aagattttct
    28741 atgctacaca ggtttctgtg aagccgccaa cctttgttgt ttttgtgaat gaagaagagc
    28801 tgatgcactt ctcttatctg cgctttctag aaaaccagat tcgtgctgct ttcacctttg
    28861 aagggacacc aatcaagctg attgcgcgca atcgcaaata agccctttta ttactcttgt
    28921 tagtattgga agcagcgagt gctgttgatg tgcggtgtct agaccttgtg tgtcaggact
    28981 tttgaccgac caataagcct taccagaaat gagaggctgc tatccaaata gagcttacca
    29041 gcaagcaagg cgtgccaagc attgatgtca catgataatc attagcccta ggctagtgat
    29101 tttttagtgc tttaaagcct atcagaacag ctatatacag ctactcaaat atgttttaat
    29161 agcctttaag agagattttt gcaggaaatc taagctgaag tttgttataa tcaaaggata
    29221 agcaaaaagg tgggagcaga tatggctaga ttaattccgg ggcggattcg caatcaaggc
    29281 atcgagcttt atgagcaagg cttggtgaaa atcatagatg acaggactga ccttcttcga
    29341 gcagaggtgg atacttatca ggttcaatat ggtatcaatg atgaggatat taggtgtcag
    29401 tgtgattatt ttgagcgaaa gcagtattgc cagcacattg cggctctaga atattttctg
    29461 aaaaataatc agaagggcaa gtcgctctca gagcagctta acaaccagct ggaaagtaag
    29521 gaggaaacta aaaagctgac ctcctttggt agtctttttt tggacagttt gcacatgaac
    29581 gaggacgaca cgaccaaata taggctttta gcttctggtg ctaaaagtcc tttctcatct
    29641 gattactggt ggagccttaa gataaatcgc ttgcccggag agaaggctta tgttatccgc
    29701 gatatcaagg cctttattca tttggtcaaa gttgagggct tttaccagat tggaaagaat
    29761 tactttgagt ctctttccat attgcagttt gatcaggcta gtcaggagct gattcgtttt
    29821 ctttggcgtt tatcaacgca ttcagataag ttagattacg aatggctatt tcctaaccac
    29881 gctcgtcatc ttcggttacc ggcaggcttt tttgaggagg gcattgacct gctgacgggg
    29941 ctttacgagt tttcatttga gacctcctct caaacctatt ctcatcttta tgttcgacct
    30001 ctggaggcag aggctggtct ctttcagttt acagttgatg ttcatcgcag ctctattgag
    30061 ctttacatta aggaaaaaaa tatagagtat tttttcaata atgaatacct gctatacatg
    30121 aacacctttt accacctgag cctgaagcag caaaaaatgg ttcaagctat tcgcagcctg
    30181 cctattgagg ccgatttggc caagcacatt cattttgatc ttgatgatca ggctaagctg
    30241 gcagctagct tgctggaatt tcgagagctt ggtcaggtga aggctcctaa aagctttgat
    30301 attagagatt tccaagtgac ttttgtcttt gatattactg aaaaaggtga gttgacctct
    30361 cagctgattt ttgactatgg gagcattcag atcagtgata aggcaagctt agaccagctc
    30421 ccctttgcta gccattataa aaaagaaagc agtatttatc gtgccttgaa gcgctttggg
    30481 ctttctccgc agttttttgc taagaaagcc ttgactgacc ccaaggactg gtatcgcttt
    30541 tttacagaag ctgttcctta ttttgaaagt ctaggtaggg ttcagctttc ctctaagctc
    30601 caagatcagc gcttaatgga aagccctcag cttacagtca aacgtgaggg aggtctttta
    30661 gatatttcct ttgatttttc aacggtttgt cagactgata ttgaaaaggc tttggccact
    30721 ttgtttagtg atcgctctta ttttgtcaat cagtcaggca agctggtcgt ttttgatgaa
    30781 gagacacaaa aaatcagccg tagcttacag gaactaagag ctaagcagct ggcaaatggt
    30841 cacctccagc tagaaggaat agctgccacc cagctgtctc atctattttc ggatctgtct
    30901 tctgttcatt tttctgagga gctagagacc ctaatcaagg acctgcagca cccggatcgc
    30961 tttgagctgg gagagctggc cgttaaggcc aaggtgagag attatcagct gcagggcatc
    31021 aaatggctct ctgtgcttga taagtatggc tttggtggta tcttggcaga tgatatgggc
    31081 ttgggcaaga cactgcaaat cattgccttt ttatcaagca ggctaaccga gacctccaag
    31141 gtgcttatct tggcaccctc tagcttgatt tacaattggt tagatgagtt tagtaaattt
    31201 gcccctcaga tagatgctgc tgtatcctac gggctaaagc cggcacgaga tgctcttatt
    31261 caagaaggac atcaggtgac gattaccagc tattcttcct ttaggcaaga tttagaaacc
    31321 tatcaggcaa atgattatga ttatttaatc ttagatgagg cgcagatgat taaaaatgcc
    31381 cagaccaaga ttgctcagag cctgcgtgcc tttgacgtga agaattgctt tgctttatct
    31441 ggtacgccga ttgaaaataa gctgcttgaa atctggtcca tttttcaaat tgttctgcca
    31501 ggcctgctgc catctaaaaa agcctttttg aaaatggagg ccagagacgt ttctcgctat
    31561 attaagccct ttgtcatgcg acgcaaaaaa gaggaggtct tgccagagct accagaatta
    31621 atcgagatga attattacaa tgagatgtcc gatggtcaaa aagcgattta tctggcacag
    31681 ctaaggcaga tgcaggagcg gctgtctgct gcaactgatg atgatattaa tcgcagtaag
    31741 ctggaaatcc tgtctggtat cacacgtcta aggcaaatct gtgatactcc tagcctgttt
    31801 atggattatc aaggaggaag cggtaagcta gacaatctaa gaaccttgct gctgcaaatt
    31861 aaagaaaacg gtcatagggc tttgctgttt tcacaattta agggcatgct ggctcttgtc
    31921 aagcaggaaa tggatcagct tggcttatca tcttatacca taacaggctc aacaccggcc
    31981 aatgaccgtc aagaaatgac acgtgccttc aataatggct caaaggacgc ctttttgatt
    32041 tccttaaagg ccggtggtgt tggactcaat ttaacaggtg ctgatactgt tattttgatt
    32101 gatctatggt ggaacccagc tgtagaaatg caggccatta gtcgtgctca tcgtattggt
    32161 caggaggaca atgtagaggt ttaccggttg attacccgcg gaacaattga ggaaaaaata
    32221 ctggagcttc aggaaaataa gcgtcatctg attaccactg ttttagatgg caaacaaggc
    32281 ctagcaagca tgtctgtcga ggagatcaaa gaaatccttg gtcttcagcc ctagcatgta
    32341 tggcttttag cacacgctct taagcctatc agctaaaggc tagtgtctgt tctctataac
    32401 aaataaggca agagaataga ggtgatgagc tagtcacatc atttttgctt tgctgccttt
    32461 ctttttagga attactttga aaaataggat tatttagttt ataataggga atgctatagg
    32521 aaggagagtg agatagaatg acaaagcatg cgtttcctct ggttgcagat ggtgagccta
    32581 ttattgagtc agctaggcag atggctttat atgaaaacga agatttgatc acaaatattg
    32641 ctggcagcta tcaagataaa cattacgacg acatcataag agaccatcaa tttgctgaga
    32701 agactcctgt cgtctctaaa ggatcccttc atcattctcc agttgtcgat gaagatcata
    32761 gctacgctca aaaggccaga aggcaagcaa agcaggatgt caaagaaaaa agacaggctt
    32821 atattgctaa aaatatggct tatagcccaa agcaggcaag caagaaaggt caaagtgggg
    32881 ccttctcttc taaaaaacca gcgacagaat tgagccgttt tacagagaaa ttaaaccaag
    32941 agtcttatat tttagctgag cttcctcgtc aatataagga gccgcaaaat accagccaag
    33001 cagctgtcaa aaaaaataat tatgactttt tgaagcgcag ccaaatctac aatcatcaag
    33061 aagacagaga tcatcgtgaa aagaccattg ctcaagagct aaacctgagt cgctttgaag
    33121 atattaagta agctttatac agccttatgt ctgtcaacat taaaaggagt taacatgtca
    33181 aaaacctatc attttatcgg aattaaagga tctggaatga gtgccttagc cctgctgctc
    33241 catcaaatgg ggcataaggt tcaaggcagt gatgtggaga agtattattt cacacaaaga
    33301 ggcctagagc aagcaggcat taccattttg ccctttagcg aagataatat ttctccggat
    33361 atggagctga tagcaggtaa tgcttttcgt gaggacaaca atagcgaggt tgcttatgcg
    33421 atgcgtcatc agctgccctt taaacgctac catgagtttt taggtgagtt tatgaagcag
    33481 tttactagtc ttggtgtagc cggtgctcat gggaaaacct ctaccacagg cttgttgtca
    33541 catgtgctca agcacatgac ggctacttct tatttgattg gtgatggtac tgggcatggg
    33601 gctgccgatg ctcgttattt tgtgtttgaa tcagatgagt acgagcgtca ctttatgcct
    33661 tatcacccgg aatattctat tatcactaat attgattttg atcaccctga ttattttaca
    33721 ggccttgatg atgtgttcaa tgcctttaat gactatgcta agcaggtgaa aaaggctctt
    33781 tttgtttacg gtgaagatga ggaattaaga aagattagct ctcctgcacc gatttactat
    33841 tatggctttg aggacactga tgatttcgta gcctttgata tcacacgcac gacaaatggc
    33901 tcagacttta aggtaaagca caagggtcat gctattggtc agtttcatgt tccagcctat
    33961 gggcgtcaca atattttaaa tgctactgcg gtgattgcta atttatttat tgcaggcttt
    34021 gatatgaagc ttgttgcaga gcatctgaag agcttttcag gggtgaagcg tcgttttact
    34081 gaaaaggtga tcaatgacac tattattatt gatgactttg ctcatcaccc aacagaaatc
    34141 attgcaacgc ttgatgctgc taggcaaaaa taccctaata aggaaatcat cgctattttt
    34201 cagccacaca cctttacaag gaccattgct ttgctagatg actttgccca tgccctaaat
    34261 gaggctgaca gtgtttatct agcgcctatc tacggctcag cgcgtgaggt tgataagggt
    34321 gatgtcaagg tggaggatct agcggctagg gttgagcgcc cagccaaggt catctcagtt
    34381 gacaatgtat caccgctgct ggatcatgat aatgcagtct atgtttttat gggagcaggt
    34441 gatattcagt tgtatgaacg ctcgtttgaa gagctgctgg ctaacttaac taaaaataat
    34501 caatgattaa gcgacctgcc ttaggcaggt tttctcgtcg taaaggagga cctatgctaa
    34561 ttagacatgt gaatcagact gactgggaga ttattgctga tatcgaacag gccaattttt
    34621 ctccccaaga ggctgtagca gccaatgtga taaaagagcg tgcagagctt atttcggata
    34681 cctttcttgt ggctgttatc gccaatcagt ttgtcggcta tatcgaagga cctgtcattg
    34741 ctgagccaag gcttgaggat cacctatttc atggtgtgac caagaatcca gcaagaggtg
    34801 gctatatagc cattaccagt ctttctgttg ctcctggata ccaaaagcag gggattggca
    34861 cagctctctt agctgcaatg aaggatttag cagttgcaca ggatcggctg ggtatcatac
    34921 ttacctgtca tgactatttg attccttact atgagatgaa tggttttcaa gatcaaggcc
    34981 tgtcagcttc aaagcatggt ggctctgttt ggtatcaaat gctatggcag ccataggaag
    35041 gctattaaag cttagcatgt attaagaatt agtaacaaaa gggggatttt attgcattta
    35101 tagtgcaatt aggatataat ggcggttgat taagtttagg aggaatggct ttgactgatt
    35161 ttaaagatga tgagcaaaga cgtcagcagc aaaaaagctt caaagaaaag attctagccg
    35221 aattagaaaa agcaaatcag attagaaaag aaaaagaaga agagcttttt aaaaaggatc
    35281 tagaggttca agaggctgct agaagaacag ctcagcttta tgcagaatat aaaagacaag
    35341 aagcactaag caataacccc aaacaagcgt ctgatatagc agctgcgtcg caagagacga
    35401 cctcaacggc ttcaacagcc cacacctctg cgattaagct agaagagaca gcagtagcta
    35461 ctggggatca agcattgtcg ccaccagagg agcctgcatt gagtgaaagc ctgcttaagg
    35521 aagaggcaag tgtcgaaggt cagactaaga agggtggtcc agtgagaaga aaaacaagta
    35581 agcgccagca gacagatcga atggccaaaa aaatttcgac agtactgata tcgtcgattg
    35641 tcgctattat tgtggtgatt ggcctcgcag ggacagccta tgtgtatagt gcccttaacc
    35701 ctgttgacaa aaatagcgat gactttgttc aggttgaaat cccagccggc tcaggcaata
    35761 agcttattgg gcagatcctt gaaaaagagg ggctgatcaa aaatagtacc gtctttagct
    35821 tttacactaa gtttaaaaat ttcactaatt ttcaaagtgg ctactacaac ctacaaaaga
    35881 gcatgagcct agaagacatt gcccaggcct tacaagaggg tggcacagca gagcctacaa
    35941 agccagtact aggaaaaatt ttaattccag agggctatac cattaagcaa attgctaagg
    36001 ccatagaaac taatagtagg gcaaagaatc gtagcaaggc taaaacacca tttcactcaa
    36061 aggatttctt gaatttggtg acaagtgatg cctttattca agagatggct aaaaaatatc
    36121 cgaaattgct aggagatctt ccaagcaagg aagtagctac ttatcagcta gaaggctacc
    36181 ttttccctgc gacctataat tattataagg aaacaacact aaaagacctt gcagaggaaa
    36241 tgattgcagc ggcaaatgca aacctagcgc cttattatga ggcgattgca gctagtggca
    36301 agacagttaa tgaggtgctg actttggcct ccttagttga aaaggaaggc tctactgatg
    36361 acgatcggcg tcaaattgcc agcgtatttt acaatcgctt aaataatggc atggccttac
    36421 agtctaacat tgctatattg tatgcaatgg gtaaattggg agaaaagaca accttagcag
    36481 aggacgctgc tattgacaca accattaatt ctccttataa tgtttatatc aatactggct
    36541 taatgcctgg tccagttgat agtccagggc ttgcagctat tgaggcgact atcaatccag
    36601 cggcaacaga ttacgtttat tttgtagccg atgtgcgtac tggtgaggtt tattatgcaa
    36661 aaacatttga agagcactct gcaaatgttg aaaaatatgt taacagtcaa attcagtaag
    36721 gacaaacatg gtgctttagc atcatgtttg tgtttctgat tcgtcaaaag aaaaaggaaa
    36781 agagaaagat aatggcagaa aagacttatc caatgacagc agcagaaaaa gaacagcttg
    36841 aaaaggaatt agaagagcta aaattagttc gtcgtccaga ggttgttgag cgcataaaaa
    36901 tcgctcgttc gtatggagac ctttctgaaa actctgaata cgatgctgct aaagatgagc
    36961 aggcttttgt tgagggacaa atctcaacct tggagacaaa gattcgctat gctgagatta
    37021 ttgatagcga tgctgttgcc aaggacgagg tggcgattgg taagacagtt gttgtccagg
    37081 aggttggcac acaaacaaca gacacttatc atattgtcgg tgcggcagga gcagatattt
    37141 tttctggaaa gatttcaaac gagagtccaa ttgcacaggc cttgattggt aagaaaacag
    37201 gagataaggt taagattgag tctccagcag ctacctatga ggttactatc atcagcgttg
    37261 acaaaacaca ataagactta tctgactatc agtgcagtgt cctgatagtc tttttagtgg
    37321 cttgcttttt aatatcagtt gttgtggtct attaaaaaga gctgcacttt agaaagtttt
    37381 aactaagata ctttatgacc tagtctcata cattaaaaaa gcgaacaggt ctaattttcg
    37441 gaatccctga aaattagacc tgttcgtttg ttttatcttg agtcagactt ttgtcacaga
    37501 ctcttttagc tatcttagcg acgctttttt tgtttaccgg cgtttcggtt taacttagtc
    37561 ctcttgcttg tgctaagggc ttgcttttca gctgtaacgt ccttgcgtgg ctggtgagat
    37621 ttataggcct taggagggtt ctttgcgaac tcctctgcaa tttgcttgcg gagccttggt
    37681 tttaaaaggt aggttgtgat caattgctga atgatactaa agaaaccacc aactagccaa
    37741 tacaagccta atccggcagg caggtaaaac gacatgacaa tcatcataat tggcatggtg
    37801 tacagcatgg ctttcatttg ttcacgttgc tcctcaggga ctgccatcat tgacagccag
    37861 gattgaacga agtataaagc cgcaattaca gctgtaagca agacgctgcg atgccccagg
    37921 tcaatgccca taaaggtact tgttgagact cccttggtaa attggaccgc aacatacatg
    37981 gcagaaaaga aaggcatttg aatcagcagt ggcaaacagc ctataccgcc tagcgggttg
    38041 actccatttt cacgctgggc cgccattaat tctgtttggg ctgccatttt ttcttcagtg
    38101 cttgtagcgt ttttgatgcg ttgattaatt ggctcaaaaa aaggctttag gtaggccatt
    38161 ttttctgatt ggtagcttgc cttccatgat tggtagagcc caagtggtag gataatcgtt
    38221 ctaacaataa tagttacaac aatgatggca agaccatagc ctagggcggt gctgttagca
    38281 aagtaatcaa tgagaaagga aacgggcttt ccaaggtaat cccaaatgat gccctccggg
    38341 tgccccttgg cgtctctgcc gacacaccct gtcaatgtca gtaggaccga taaggcaagt
    38401 cctgagaaaa gtatgcgatt cgttttgagt ttcaatgtgt ttgtccttta atttttaata
    38461 tacctaacca ttttactgtt tttttgagaa attaacaata gttctacagt aggattttta
    38521 attgctgatc ctaaaatcat ggaaatcctc aaagtgagat ggattaacat caacataggt
    38581 cacctttgcc catttagaag gtccttttct gatttcctgg ataaagcgcg tcatctttgc
    38641 agggtcacta gcctgtgcta aaatctcaac agtcccatca ctattgttcc acacgcggcc
    38701 gtaaatatca ccaatttcca aagctagtgc gtaggttgaa tagcgaaagc caacaccctg
    38761 caccctgcct gaaacgatta gtctgacctt tttcataagt cacctctttt ctttttatta
    38821 tagcatagat agcttataaa tactaaaagt tgtcatggag caggcagcca aaggataggc
    38881 aaagactgca agtgggctat ctgctgaggt aaacaatagg tcttagtgca gcaaggctat
    38941 gtttatggtt agctctcctt cttgtcttct aaaaaggaaa gctaatgggc ttacgacacc
    39001 tgataagggg agaaagctcc ttttaggctg atagccttct gatggttttt atgcaaaaga
    39061 gtgaacaatt ttgtg
//
LOCUS       DARYLJ010000016        39068 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYLJ010000016 DARYLJ010000000
VERSION     DARYLJ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39068
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(93..464)
                     /locus_tag="TU746_000743"
     CDS             complement(93..464)
                     /locus_tag="TU746_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891108.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TU746_000744"
     CDS             683..1321
                     /locus_tag="TU746_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL0891109.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TU746_000745"
     CDS             1517..2053
                     /locus_tag="TU746_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0891110.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TU746_000746"
     CDS             2916..3320
                     /locus_tag="TU746_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL0891111.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TU746_000747"
     CDS             complement(3376..4860)
                     /locus_tag="TU746_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL0891112.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TU746_000748"
     CDS             5219..6442
                     /locus_tag="TU746_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0891113.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TU746_000749"
     CDS             complement(6532..6891)
                     /locus_tag="TU746_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL0891114.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7775
                     /locus_tag="TU746_000750"
     CDS             7056..7775
                     /locus_tag="TU746_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0891115.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEAGWVSC"
     gene            complement(7820..8647)
                     /locus_tag="TU746_000751"
     CDS             complement(7820..8647)
                     /locus_tag="TU746_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL0891116.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8908..9036
                     /locus_tag="TU746_000752"
     CDS             8908..9036
                     /locus_tag="TU746_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL0891117.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9090..10403
                     /gene="obgE"
                     /locus_tag="TU746_000753"
     CDS             9090..10403
                     /gene="obgE"
                     /locus_tag="TU746_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL0891118.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10524..10682
                     /locus_tag="TU746_000754"
     CDS             10524..10682
                     /locus_tag="TU746_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891119.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10735..11439)
                     /locus_tag="TU746_000755"
     CDS             complement(10735..11439)
                     /locus_tag="TU746_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL0891120.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11774..13174
                     /locus_tag="TU746_000756"
     CDS             11774..13174
                     /locus_tag="TU746_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0891121.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13184..14278
                     /locus_tag="TU746_000757"
     CDS             13184..14278
                     /locus_tag="TU746_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL0891122.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPRVVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14384..16378
                     /locus_tag="TU746_000758"
     CDS             14384..16378
                     /locus_tag="TU746_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL0891123.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16392..16709
                     /locus_tag="TU746_000759"
     CDS             16392..16709
                     /locus_tag="TU746_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0891124.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16706..17041
                     /locus_tag="TU746_000760"
     CDS             16706..17041
                     /locus_tag="TU746_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0891125.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17041..17475
                     /locus_tag="TU746_000761"
     CDS             17041..17475
                     /locus_tag="TU746_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL0891126.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17550..18929
                     /locus_tag="TU746_000762"
     CDS             17550..18929
                     /locus_tag="TU746_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0891127.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18926..19078
                     /locus_tag="TU746_000763"
     CDS             18926..19078
                     /locus_tag="TU746_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891128.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19235..19975)
                     /locus_tag="TU746_000764"
     CDS             complement(19235..19975)
                     /locus_tag="TU746_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0891129.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(19975..22140)
                     /locus_tag="TU746_000765"
     CDS             complement(19975..22140)
                     /locus_tag="TU746_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL0891130.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22332..24323
                     /gene="uvrB"
                     /locus_tag="TU746_000766"
     CDS             22332..24323
                     /gene="uvrB"
                     /locus_tag="TU746_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL0891131.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24662..24805
                     /locus_tag="TU746_000767"
     CDS             24662..24805
                     /locus_tag="TU746_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL0891132.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24817..26355
                     /gene="dltA"
                     /locus_tag="TU746_000768"
     CDS             24817..26355
                     /gene="dltA"
                     /locus_tag="TU746_000768"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL0891133.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26352..27599
                     /gene="dltB"
                     /locus_tag="TU746_000769"
     CDS             26352..27599
                     /gene="dltB"
                     /locus_tag="TU746_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL0891134.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27617..27856
                     /gene="dltC"
                     /locus_tag="TU746_000770"
     CDS             27617..27856
                     /gene="dltC"
                     /locus_tag="TU746_000770"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL0891135.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27849..29102
                     /gene="dltD"
                     /locus_tag="TU746_000771"
     CDS             27849..29102
                     /gene="dltD"
                     /locus_tag="TU746_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL0891136.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29136..30110
                     /locus_tag="TU746_000772"
     CDS             29136..30110
                     /locus_tag="TU746_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0891137.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30651..31910
                     /locus_tag="TU746_000773"
     CDS             30651..31910
                     /locus_tag="TU746_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0891138.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     GKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32083..33783
                     /locus_tag="TU746_000774"
     CDS             32083..33783
                     /locus_tag="TU746_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL0891139.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33812..35944
                     /locus_tag="TU746_000775"
     CDS             33812..35944
                     /locus_tag="TU746_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL0891140.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSTAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLVFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36020..37324
                     /locus_tag="TU746_000776"
     CDS             36020..37324
                     /locus_tag="TU746_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0891141.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37325..38185
                     /locus_tag="TU746_000777"
     CDS             37325..38185
                     /locus_tag="TU746_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0891142.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38210..39040
                     /locus_tag="TU746_000778"
     CDS             38210..39040
                     /locus_tag="TU746_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL0891143.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT        10866 a         7374 c         9044 g        11784 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggctggc tgggttagct gctgaattga tagtaaaaaa gaccagtctt
     7801 agactgatct gtagggtgat tagatcgccc attctcctcc tcggaagatt ggaatgactt
     7861 ctccgtcttt ggtaatgcca tcgatatcca tttgttcaga accaatcata aagtccgcgt
     7921 gggctgttga gcgatttagg ccagccgctt cccaaatgtg ctgctcaggc attccaagtc
     7981 ttaggtcagt tcctggtgcc ctgtagtgaa ggctgtcaaa ctgataatca ttgaggagcc
     8041 ttgccttttt ttctaaacgt tcctgatgtt ggtcccaggc cttgacagga tctgtctcgt
     8101 aaatgcgatt cattttgaaa atggcatccc acaaagcgtc cacctgctct tcttcgcttg
     8161 tcaggtttgg aaaaaccata gcagcccatt cgggaccggc tgcagctgct agattccagc
     8221 tgactttgtt ggcctgagtg gcagcccgct gtttttcaag agcaatagct gttgcgcgtg
     8281 ttgctccagc tagcctatca gaatcaatat cagcaaagac gtttggattg gcagagcgaa
     8341 tgactaagcg gcttgctttt tgatcaagga gataatgtga ctgttcaacg acataatctg
     8401 gtacctgcaa gagacggtct tcatcagcct taagaagctt ctcgcgtgtg atctgatcgt
     8461 cattatagtc aacaagaacc tcagctgcac cagcctcata ggcttttttg gttaatagcc
     8521 gcgcaagctt gtgttgctct actgcaatag aaatgagtag tgtgtgacct ttttgaatgt
     8581 tgactccttt tttgataaga aggttagcgt atttttcaag ataatcgtca aaatgtggca
     8641 aaaccatagc agtctcctaa tatgttaatg ttgcaaaatt taatgtatca tatttgcgac
     8701 tatttcacaa ggagctagcc tgtttcatag gctaaatgtc tcctagaatg cctatcgtaa
     8761 aaggctcagt gttggttttc tctgatgagt taaaaaacga tccctttttt gatcagtttg
     8821 cgctgccctt gctaatagat atttgcttaa tagcgacatt cgtgttaaga tataagagga
     8881 aaaaatcaat agatgaggta tttaacagtg gcatttggag aaaatggacc tcgcaaaaaa
     8941 actgcctttg aaaagttgac aacagttgtt gtgatcgtga tggttcttgt gactgtcggt
     9001 ggacttattg cgggtgccct gtcagtattg atgtaagaaa acgctgaaag gcgttttttt
     9061 aggataagag aaggtttgag aagaaaagta tgagtatgtt tttagatact gctaaggtca
     9121 gtgttcaggc tggtcgtggc ggtgatggta tggtggcctt tcgtcgtgaa aaatatgtgc
     9181 ctaatggcgg cccttggggc ggtgatggtg gcaagggtgg ctctgtcatt ttcaaggttg
     9241 atgaaggttt gcgtacccta atagactttc gctacaatcg taagttcaag gccaaatccg
     9301 gtgaaaaagg catgactaag ggcatgcatg gtcgtggctc agaggatttg attatctcag
     9361 tgccacaggg aacgactgtg cgtgatgctg aaaccggtaa ggttctgacg gatctggttg
     9421 agcatggtca agaatttgtc gtggctaagg gtggtcgtgg cggtcgtggg aacattcgtt
     9481 ttgcaacgcc gcgcaatcca gcacctgaga ttgctgaaaa tggtgaacca ggagaggagc
     9541 gccaattaga gctagagctt aagattttgg cagatgtggg actggttggt tttccgtcag
     9601 ttggtaaatc aacgctacta agcgtggtct catcagccaa gcccaagatt ggtgcttatc
     9661 actttaccac tattgtgcct aatctaggta tggttcgaac caaatctggt gagagctttg
     9721 ctatggcaga tcttccaggc ttaatcaagg gagctagcca gggtgtgggg cttggcactc
     9781 agtttttgcg ccatattgag cgtacacgtg tgattctaca tgttattgat atgtcagcag
     9841 ctgaaggacg agacccttat gaggactatg tggcgattaa taaggagtta gaagcatata
     9901 atcttcgtct tatggagcgt ccgcaaatta tcgtcgccaa taaaatggat atgccagagg
     9961 caaaggagca gttgcagcgc ttcaaggaac agttagctgc tcagtatgat gactttgaag
    10021 aactgccaat aattttcccg atttctagct tggcacatca aggcttggat agcctattag
    10081 aagcaacagc agagctatta gcaaaaactg atgatttctt gttgtatgat gaggctgatt
    10141 tggctgagga cgaggcttat tatggctttg cggctgagga aaaggccttt gagattagtc
    10201 gtgctgatga tgcagcttgg gtattgtctg gtgagaaatt agagcgtctc tttgtgatga
    10261 ccaatctgga gcgcgacgaa tctatcatga aatttgctcg tcagctacgt ggcatgggtg
    10321 ttgatgaagc gcttcgtgag cgtggtgcta aggacggcga cattgttcgc attggcaagt
    10381 ttgagtttga atttgtagac taatgacaaa taccaagctt agctgttttt tgtagcaagt
    10441 gatgctgagt catatctgaa gtaggctgtt tgctcaattc acagcaatga ggtcttggtt
    10501 gatgtgagct agggaggttt tttatgggag ataaaccaat atccttcaag gataaggacg
    10561 gtaactttgt ttcggcagca gatgtctgga atgctgaaaa attagaagaa ttatttaatc
    10621 tcttaaatcc caataggcgt ttgcgtttgg aacgtgacaa attaaaaaag gatgaagctt
    10681 aagtgcactt cctctcaatc gttagattta gtgtctaact tttgagggtg cacttcaagg
    10741 cttcgtcctt ttttgatgct ttttttcttg gtgatgctgc aaatgtagcc aattaaaaaa
    10801 ggtgtaaatg tcattaacaa gaaaggctgc aaaacaaatg accactgcgt attggctggt
    10861 atttgcttga gcagcataga gccacaggag aattaagacc aaatcattaa gagcataggc
    10921 caaggcaaaa taagggctac gtttgtagct taagtaggct gctgaaaaag aggtggcaat
    10981 agataaggta gaaacaggca gataggctgt cttaagatag gctaagatag catagaacaa
    11041 gctggtaact agtatggtaa gaaccactaa gcgcagccgg tctgctgttg tcaagcgtga
    11101 gatggttacc tgagatgtct ggtcttcaaa tgggtggctt agccaggtaa acagtgacaa
    11161 aatagccatc ggcagggtca tgaagagata ggttatcagc tccccgtaat aactgtttaa
    11221 tagtgacaga taggcataaa taagggagaa aataatggcc aagctctgtc caatcggatt
    11281 tgccttggca ctaaagatta aagctgtcac accgattaag gaagctatca gtgctaaggg
    11341 agcttgttct ccaaagaaaa aggcactgag gagaatagcc gaaatggagg ttaaccaaag
    11401 cgtccactcg gtttttgtaa aatagtttaa ataagccata tccttattca agcataggcc
    11461 tttttatctg tcaatagggt gtcgacctta gggaaaaata agctaatacc tgccatagtg
    11521 caattggttg tgaggcacta atactagcag ataatggtgt taactagagg caaatgagct
    11581 aagagtttcc ttattggctg ctgctaatac tccttgttga ctggtttaga agaaaaggac
    11641 taagagcctt agcttggctt tgtcagttag tttccttgat gataaggaaa aactagattt
    11701 tttaaagcgt ttacagtgtc cttttttctt cctataatag gggtataagt gacaaaaaga
    11761 aaggaaaaag catatgaagc aatcaaaacg ccgttaccaa tttccagaag gttttttgtg
    11821 gggaagctca acatctggcc ctcaaagtga ggggactgtt tctggagatg ggaagggacc
    11881 tagcaattgg gactactggt ttagtctgga gccagataag tttcatcatc agattggtcc
    11941 agaggtaacc tcaacctttt acaccaacta caaaagcgat attgctcttt taaaagagac
    12001 cggtcacaca gcttttcgga cctctattca atggtctcga ctgattccag aaggggttgg
    12061 tcaggttaat ccaaaagctg tagcctttta ccgagaggta tttcaggaaa tcatggctca
    12121 ggacattaag ctgattgtta acctctatca ttttgatctg ccttatgcct tgcaaggaaa
    12181 gagaggctgg gaggctaagg agacggtctg ggcttatgag acctatgcta agacctgttt
    12241 tgagcttttt ggtgatttgg tggatacatg gattaccttt aacgaaccta ttgttccagt
    12301 cgaatgcggt tatttggggc attaccacta tccttgcaag gtagatgcca aggcagctgt
    12361 tcaagtggct taccataccc agttggctag ctcacttgct atcaaggcct gccacgagtt
    12421 gtatcctaag cataggatta gtattgtgct taatgtgact cctgcctatc ctagaagtga
    12481 tcagccagaa gatgtcaagg cagcgagaat cgcagagctt ttccagacta aatccttcct
    12541 agatccgtct gtcttaggag tgtacccaga agagttagta gttcttttag aggcagctga
    12601 tttattgccc cagtatagtg ctgatgaatt ggctattatc aaaaacaatc ctgttgattt
    12661 cttgggagtt aattactatc aacctttgcg tgtgcaagcg cctagcaaaa caagacaaga
    12721 tggtgaacca atcacgctag cctcttattt tgaaccttat gatatgccag gcaaaaaggt
    12781 taaccctcat cgcggttggg aaatctatga gcagggcctt tacgacattg ctcttaattt
    12841 aaaagagcat tatggcaata ttgactggtt agtaactgaa aatggtatgg gagtagaagg
    12901 tgaagaagcc tttttagttg atggtcagat ccaagacgat taccggattg cctttatcga
    12961 agaccatttg attcaattgc acagggcttt agaagaaggc gcgaactgta aaggctacct
    13021 cctgtggacc tttattgatt gctggtcttg gttaaatgcc tataaaaatc gttatggctt
    13081 ggtagccttg gatttagaga ctcaaaaacg aacccttaaa aaatctggcc actggtttaa
    13141 gaccctgagt cagacaaatg gttttgataa ataggagcgt atgatggtca ccttaggatt
    13201 ttccctttac cctgagcggc atggttttgc taagagtaag gcttatattg atttactgca
    13261 ctgctatgga gccaagcgct tgtttatgag cctcttacag ttggcgccaa atgatcccaa
    13321 gacctttaag ttttatgcgg atctgattgc ttatgccaat tgcttgggca ttcgggtcat
    13381 tgcagacgtt agccctgctt ttatcaagca ggctggttgg tcagatcagg ttattgaaga
    13441 ggctcatgct tttggcttag caggcttgcg tttagatgag gccttgcctt tagaggatat
    13501 tgttaggcta acgaaaaact cttttgggct taagattgaa ctcaatatga gtactgacaa
    13561 gagtttattg acagccttgc taaaggcagc tcctgatcgg agtaacctca ttggttgtca
    13621 taatttttac ccgcacgcct ttaccggcct gtcactggag cattttaagg aaatgtccca
    13681 tttttaccac gagcatggga ttgcaacggc tgcttttatc acagcccaat cagcaaagga
    13741 aggcccttgg ccgctgtcag agggcttacc gactgttgag gctcatcggc aattgccaat
    13801 tgacgtgcag gtggaactga tgaaggcgac aggaactatt gatactgtca ttttgtccaa
    13861 tcaattcatc actgaagatg aactcgttca gtgccgtcaa gccttggata gatcagtcat
    13921 gtctattaag gtcaagcctc tggttgattt gacggacata gaggagaaga ttatctgtta
    13981 cccacattgt tatcggggag atgtatcaga ttatgtgatt cgctcaacca tgccgcgtgt
    14041 ggtatatgct caagaagcaa ttgctccaag agagcagccc aagcaggtta agcgaggcag
    14101 tattatcatt gataatgacc gttacaacag gtacaaggga gaattgcaaa ttgcactcaa
    14161 agcctttacc cttagctcaa aggccaatgt ggtcgccaac attaaagagg attacctaag
    14221 cctattagac gagttgaagc cctggcagga gttttcattg gtgattgaga ctgactagtc
    14281 tggcttcaca atcgatacgg aaaatgatgg tcactttttt caggaaacat ttgctaaact
    14341 aagagagtaa agaaagcgtt ttctaaaaga cgaaggagga atgatgctat caaaaaaaga
    14401 aatggctata gtagcatttc taatcagcca aaaagggcag tttgtctcta gtgctacctt
    14461 ggctaaggct attggcatga gtgatcgcac agtcagaaaa tacctaaagg agctgattag
    14521 cagccttcct agtaagggag cgcacatcat ttccaagcaa ggtcagggct actgtttaga
    14581 gattgatcat tctatggcgt ttgagatctt ttggcaggaa agcttggcct ctaaaaagcg
    14641 cttggctgat gtgactcagg tggaagaaac agttgatcgg gagcattatt tgctaaataa
    14701 attcttcttt gaagagcccg tttgggattt tgaagagctc tgccaagaat tgtatattag
    14761 tcggacgacc ctaaaccatg ttttagcggt tattagagac cgtattaggc cttatcagct
    14821 acagcttgat gtgagtcatc agcgcgttca ggtgacaggt aaggaagagg ctattaggca
    14881 ttttatcatg gattattttt ttgctaccag ctttgatgac tccatgtacg ccatagtaga
    14941 caataccttt cttgatcata tcaagtttgc tgatatcaca ataattgttt tagatgaatg
    15001 tcgagatgcc aaactaaagc tttctgattt tgtcatgcac aatttggttt tgcacattgc
    15061 cctaatggtt cagcgtattc ggtctggcta tccgttagca tttttttcca ttccagcagc
    15121 tattcgccaa tcagacgagt atcaagtggc tctacgtatt ttatatcgag tagaagaagt
    15181 gatgggcatt cgttttccta aagaagaagc taactatatt gctttacacc tcaaggttaa
    15241 gcattccgtt gatggcagcc cacaggacaa taaggccgat gacttgctga gaagtcattt
    15301 aaaagcaggt attgtcaagg ctagtcagct gacaggtatg tctttggagg ctgatagcag
    15361 cttgcttcaa ggcctattgg cccatatgaa gcctttagcc acaaggcttg aaaatcatat
    15421 tcagctgacc aatcccttaa ctgaggagat taaaagcaaa tacccagagg cttttgccct
    15481 gactaagcaa gcttttgaga atattcctga gcttcaggct tatgacctgt ctgatgacga
    15541 atgggcttac attagcttgc atatcatggc agctattgag cgctattcca atcgtcacaa
    15601 actgagggtg cttgtggttt gtgccacagg ctatggcagt gccatgatgc tgaaaaatcg
    15661 cttggaaaag gaatttgaag gtcgctttca gattgtagat gttatcagct actatgaaat
    15721 aacacaggaa cgactgcaaa cggttgatgt gattatttct tctatcagcc ttgctaatgt
    15781 catgttttta acgccagtca ttactgtcag tgtcttttta tctgatcaag acatcaaagc
    15841 cattcgccaa tttatcgggg agcaggaggg aataagaaga gaagctgcgt cgtcatcgca
    15901 gatgagcttg gaaaaagcag agcagattct aaaaggtgtc tttagtccta agcgttttct
    15961 ttatgtgaaa gaaaaactat caaagaaggc cttgctgtta aagatgattg cttgtcttga
    16021 cgaagcaatg gatgaagcct ttgttgaggc cttttatcac caaatcgtgt tgagggaaaa
    16081 ttatagctca attgtttttg gtgaggtgct tgcctttcca cacccggcta atcccatgac
    16141 ctattctgaa caggtggtgg tggctgtctg tcaagagcct attgactggg acgagagtca
    16201 tcgggctgtt cactttatct ttttgttgtc accgtccaag ggacgtaaca gctatttaaa
    16261 atatatctca ccgagcttgg tgtcttttgt caatcaagca gagcttcagc aggctttatt
    16321 agaagaacca agctatgcac aattcatcac attatttacc ccactcatca ctgaataaaa
    16381 ggagaagtat tatgaaaacc attatgttag tttgtaatgc cggcatgtca accagtatgc
    16441 tggtgactaa aatgcaaaaa gccgctcaag cgcgtggcat cgaggttgag atttgggcag
    16501 ttcctgtgag cgaagctgac aatgaggttg ctgctaaaac cattgatgtc ctcatgttag
    16561 ggccgcaggt caaattctta ctaaaggact ttaagaccaa atttgaaccg gcaattaagg
    16621 tagatgtcat taacatggct gactatggcc tcatgaatgg tgacaaggtg cttgaaacag
    16681 ccctaacaat gatggaggaa gaggtatgac acaatcatca aacctagagg ccattatggg
    16741 attaatcatg tatggcggtg aggccaaggg caaggctgta gaagctattc atgcagctag
    16801 agatggtcaa tttgaaaagg ctcagcactt gcttcaagag gctacacatt ctttaaatgt
    16861 tgcccataga tcacaaacca atttgctatc tcaggaagca gctggagatc aggttgattt
    16921 gtctttattg ctggtgcatg gtcaggatca tatgatgaca gccttagcct ttattgattt
    16981 ggccaaggaa ttggtcgctg tttatgacaa aatatcaaga atccaaagag gtgagctatg
    17041 atgatgatta cagcagaagg agatgtctct gtcactcaat gcttcaaggc tatactaagc
    17101 tctctccaag aggattatca tgaaaacacc ctgagacggc tgccaccagc tgaattaaaa
    17161 gcagggctaa gctacataaa gcattatggc aaaagcaagg agcataacgt tagagtgctg
    17221 atcacagcct tagaagctcc gcacttatat gctgcttgct ttagctctaa tcatgggcta
    17281 aaaacattaa gctaccgctt agaagctctg ggagagaagc gtaccaaaat aacctattgc
    17341 tacgactatc agccacttga tgtctttcaa aaagccaatc agctgatcat tgggaagctt
    17401 tttaagaaga gcttcaaacg gcaatcacaa gcccaattgg cagcccttat ccaatatgct
    17461 aagcagctaa gctaggggaa gatttgagta cagattatct ggctgattat agggcttatc
    17521 atactaaaaa atagaaacag gagaaaatta tgtcacattt ttcggataag tttatggaga
    17581 tttcaggaaa gatgggatcc cagcggcatt tggttgccat tcgtgattcc tttatttcgc
    17641 taatgcccat cacgatggcg ggctctgttg ccgtcttgct gaatgttttc ttgcgtgata
    17701 ttccaaacaa tatgggctgg actggttttg cagcagccat gcagcccatt attgacatca
    17761 atggttatgt gtattttggg acaattggta tcatggcact cttttttgcc tttgcttttg
    17821 ggtatcattt agctcttatg cacaaggtga atcctttggc tggaggttta atctcctttg
    17881 cttcctttgt cgccaccctt cctcaaagct taaccatttc cacaccactt gaaggggcgt
    17941 cagcaagttt attagcaggc ttaaaggata tgggactatc agtggtcact gcaaatggag
    18001 cccgagtttt agaaacaagc cagtggggag caattgccct caaatatgct ggagcaacag
    18061 gtctttttac agcattgatc attggctttt tatctagctt tgtttatgcg actttgacca
    18121 aacgtaacct gaccatcaaa ttgccagata atgtgccacc tgcggttaat aaggcttttg
    18181 cggctattat tccagggaca gtcgcgattt atgtgtcagc gatcgtagct taccttattt
    18241 ttgccctcac aggctcgtct ctaagtgata tgatttcgac ctatatccaa ttgcctttgt
    18301 tggggctgtc tcaagggctt ggctctgtta tcctgttaac cttcttggtt caattgctct
    18361 ggttctttgg tttgcatggt cacaatgtct tagcacccgt gcttgatggt gtgtacttag
    18421 tggctctaac agaaaataca gctgcctata ataccagtca gagcgttgct aatctgcctt
    18481 atctctggac gagaggctcc tttgatgcct atgcacaaat gggtggttca ggtgttactc
    18541 tggctctgat tattgctatc tttattttct caaaacgtga ggagcacaag accattgcca
    18601 aattatcagc accgatgggc gtgtttaaca tcaatgagcc aattaccttt ggtatgccta
    18661 ttgtcttgaa cccaaccttt gctatcccat ggctaatcgt accaccaatt tgtgctagca
    18721 ttgcttatgc tgccacagca ataggcttga tccctcccgt tttcttgcca gttccttgga
    18781 ttacgccagt tggactttac gcttacttgg ctactggagg tagtgttatg gcaggtctgg
    18841 tttccttgtt taacctcttt gttgcctttc ttatctgggc accatttgtc atgtcagcta
    18901 ataaagaaaa agcgagtgac ctttcatgac agcaaaaaac ggagcaagct ttttaatggc
    18961 tataggattt ttccttattg ccattagtcc aatggttggc aacaaatacc tacatatcgt
    19021 gacaggacta gcttttgttg gcttagggta ttatctcact aagcgcaagc gtccttagtc
    19081 aatgcgagca gctagcccct atgaaaagac aaacctaagg gctagccttg attttctatc
    19141 ttggttatcg catttaaaag caagcaaaaa agcaagggta gatgcttacc tttgcttttt
    19201 ttattttttg acctttaata gaatatcttg ctacttaaac atttaagacc ttatctaaaa
    19261 attcaattaa gcgtgggtgc ttagggtgat caaagatttc ctctggagta ccgtcctcta
    19321 ggaattggcc gccgtctgta aagatcacac gattagccac ttgacgagca aagcccattt
    19381 catgtgtcac aatcagcatg gtcatgccct gctctgctag gtctttcata acgtttaaga
    19441 cgtctccaac catctcaggg tcaagagcag aggtaggctc atcaaagagc atgatatcag
    19501 ggttcatggc aagacttctt gcaattgcaa cacgctgctt ttgaccacct gatagacttc
    19561 ctgggaaagc gtcagcctta tcagctagac cgaccttctc tagaagagca agtccctttt
    19621 ccttagccgc ctcctttgag acctttccaa gctcaactgg tgcaaaggta atgttatcaa
    19681 ggactgtcat atgtggaaag agattgaagt gctgaaacac catgccgata ttttcacgag
    19741 ccttatcaat attggtatta ggatctgaaa gttcaaagcc atcaaccaca accttaccac
    19801 tagtaatgga ttcaaggaga ttgagggtgc gcaggaaggt tgattttcca gagccagatg
    19861 gcccgataat acaaacgaca tcaccctcgt aaaatttagc attaatgcct tttaagacct
    19921 cattttgccc ataggatttg tgtaaatctt gaacatcaat ttttaattct gccattagtt
    19981 aagcctcttt tctaaacgtt ttgcaagcct tgttaagagt gtaatcataa tcaagtagat
    20041 aactgctagg atagcataca tgcggaagga ttgatagttt ctagcgataa tgattttccc
    20101 tgtttggaag agctccacta aaccgatcgc tgagactatg gtcgtatcct tcaaggaaat
    20161 gacaaactga ttgatgaagt ttggcagcat tagcttaatg gcctgaggaa ggataatcct
    20221 tcgcattgtt gtgtgatatg acaagcccaa gctgcgacta gcctccattt gacctgccgg
    20281 cacagcctcg atacccccac gaacaatttc ggcaatatag gctccaccat ttagcgaaag
    20341 tgcaatagta gcagctacaa aatcgttaat cggtgattga tgcccagtca tgctttcaat
    20401 gaggtttggc actccccaga agataaaggc agcaacaatc atcaagggga taccacgcac
    20461 cacatcaaca aagatagtag aagccatgcg caggttcttt gatggggata cagccatcat
    20521 tccaaaaaca ataccaataa ccaaagcaat ggcaaaggag atgagtgtca gaccaagggt
    20581 tgttccaagc ccagccaata attgcttgta gttattagct aaaagtccat aaatagttga
    20641 ctcatcggct gttttgacag atgcctctga atcaaggtat ctgctgatga tggcgtcgta
    20701 ttttcctgat gctttaagag cagccaaacc gttgttaaac atttcgatga gctcagggtt
    20761 ggctcctttt ttaacagcaa aaccatactc accagaaggc tctcccttga taggaatatc
    20821 aagcttgtgg cctcgctgaa tagcgtacct taaaatagct tcatcatcca taagcccgtc
    20881 aatagaacca gaatttaagc tatcgtacat tgaggaggcc tcatcaaagg cttttagacg
    20941 gtaaccataa atatccttgt tgctttcaag gaaatcatag gaggctgttc cttttttggc
    21001 accgactatt ttacccttga ggtccttgta tgatttgata gagcttccgg atttgacccc
    21061 aaggcgaatg tttgatgtgt agtaggaatc tgaaaaatca aaaatctcac gacgtgcagg
    21121 tgtgatagac atacctgcaa taacagcgtc agcctgacca gcttgaacag catttaaagc
    21181 agcgtcaaag ccaggattgc tgatctcaat ggtaaagcct tgctgcttag caattgcctt
    21241 gatgaggtcc atatcaatac cgacatattc tccgctgcca atttgaaatt caaagggagc
    21301 aaaggaggag tcagccacga ttttataaac cggctttaaa ggagtggcct tagcagaggc
    21361 atcgccagta gccttgcctg ctgtgacctt gtcattgctg ccaagccatt ttgtcatgat
    21421 agcttgatag gttccatcag ccttcatagc gcctaaggct tcattgaagt cgtcaatgag
    21481 ataatcatag ccgctgcctt ttttgacagc aaagccaaag cttccaatag cctctccctt
    21541 catgttgatc gcaagatcct gcttttggtt aatggcatat tgaatgacag gctcgtcgtc
    21601 cataacagcg tcaatagagc ctgttgcaag actgttgtac atcaggtcac ctgtgtcaaa
    21661 tgttttaaca gtataaccat acgatttttt gtatttatct aagaaggctt gagcagctgt
    21721 tccattttta acaccgactg tttttccttt tagctcgcta tatttcttaa tagggttagc
    21781 ctttcttgta gcaataacaa tttttgtatc gtaataggga tctgaaaaat ggaagacctt
    21841 ttgacgagca gcagtgatgg tggtgcctgc cataagggcg tcagcttgac cagactgaat
    21901 ggcattgaca gcagcatcaa agccagggaa tgtcatattg atattccaac cctttcgctt
    21961 tgctacttca ttgatgatgt caacatcaat ccccttatac acctgatctg aatccttgaa
    22021 ttcaaacggt gcataagcag tatcagaaac aatatcaatt gtctctgcac ttgcaatccc
    22081 agcagtcatc aaaacaactg acagcattgc aagcatccat gcttttaatg tgtttttcat
    22141 actagtctcc ttaataaaaa taaaaaatat gcctaattat agcagatttt tttcaaacaa
    22201 gcaaatcatc tcttcttttt atgtcataaa acctaacata aacaactaaa atagtcaaaa
    22261 agctttgata gagtctttaa gtccttaact atgttacaat agataagaga taagatattg
    22321 aggaccaata aatgattgat aaacgtgatt ttaaagcatt taagctcgtg tcaaaatatg
    22381 ccccctcagg agatcagccg caggcgattg agaccttggt tgataacatt gaaggtggtg
    22441 aaaaagcgca gattttacta ggagcaacag gaacagggaa aacctatacc atgagtcagg
    22501 tgatcagcaa ggtcaacaag ccaacgttag tggttgctca taacaaaacc ttggccggtc
    22561 aattgtacgg tgagtttaaa gagttctttc ctgaaaatgc tgtcgagtac tttgtatcct
    22621 actatgacta ttatcagcct gaggcctatg ttccttctag tgatacctat attgaaaaag
    22681 acagctctgt taatgatgag attgacaagc tgcgccattc ggccacctca tcgcttttag
    22741 agcgtaatga tgtgattgtt gtggcttcgg tttcttgtat ttacggattg ggctcaccaa
    22801 aggaatatgc tgattcagct gttagcctgc gtcctgggca ggagatatcc agggatcagt
    22861 tgctcaatgc ccttgtagac attcagtttg aacgcaatga cattgatttt caacgtggac
    22921 gctttcgtgt gcgtggtgat gtggttgaag tatttccagc ctcaagagat gagcatgcct
    22981 ttcggattga gtttttcggt gatgagattg atcggattcg tgaaattgaa agcctaacgg
    23041 gtaaagtatt aggtgatgct gatcatttag tgctttttcc ggccactcac tttgtgacca
    23101 atgatgagca catggagcag tctattagca agattcaggc agaattagca gaccagctta
    23161 agctatttga agcagaaggc aaattgctag aggctcagcg cctgcgtcaa aggacagaat
    23221 acgatattga aatgctacgt gaaatgggct acaccaatgg ggttgaaaat tactcacgtc
    23281 acatggacgg gcgttcggca ggagagcctc cttataccct gttagatttc tttccggatg
    23341 attttcttat catgattgac gagagtcaca tgaccatggg acaaattaaa ggcatgtaca
    23401 atggagacaa ggctagaaag caaatgcttg tggattatgg ctttcgtctt ccgtctgcct
    23461 tagacaatcg tccgcttcgt cgggaggagt ttgaaagtca tgtgcaccag attgtctatg
    23521 tctcagcaac gcctggagat tacgagatgg agcagactga tacgattgtg gagcagatta
    23581 tcagaccgac aggtctgctt gatccagagg ttgaagtccg gccaagcatg ggacaaatgg
    23641 acgacttgct tggcgagatt aacctgaggg ttgaacgagg tgagcgcacc tttatcacaa
    23701 ccttaaccaa gaaaatggcg gaggatttga ccgactacct caaggaaatg ggtgtcaagg
    23761 taaaatacat gcatagcgac atcaagacat tagagcgtac agaaattatt cgcgaccttc
    23821 gtttaggcgt ttttgatgtc ttgattggta tcaatctgct gcgtgaaggt attgatgttc
    23881 cggaggttag ccttgttgct attcttgatg cggataagga aggcttccta agaaatgaac
    23941 gaggtttgat tcagacgatt ggtcgagctg ccagaaatgc tgatggtcat gtgattatgt
    24001 atgctgatcg tatgacggat tccatgcagc gcgctataga tgaaactgct cgtcgtcgtg
    24061 ccatacagat ggcatataat gaagagcatg ggattattcc gcaaaccatt aaaaaagata
    24121 ttcgtgattt aatcagtatt tccagagcag ttgaagcaaa agcaacagaa gcagagacaa
    24181 attatgagtc aatgacgcgg tctgaaagac aagaagctat taagcaattg caaaaaaaca
    24241 tgcaggaagc agcagagctg ctggattttg aattagcagc acagcttcgt gacctgatct
    24301 tagagttaaa agcaatggat taagacctga taagctaagt ctggctgtat aagctaggct
    24361 ttttatctgc ttttgagttt gtcctttagg tctgtcttat gatctttggt accagataaa
    24421 tgagtgatat cttgagcttg atctacgcaa gagctagtgc agccactagc ttcagactac
    24481 tttaatgatt taatgaaaga ttgattttga taagacaatt ctgatataat gtaaagtagt
    24541 tggcaaaaat agaaacatta aataaatttt ctttttaata atttaacttt taccttgtca
    24601 acaaggctat tttcggatag aatttcttag tacattattt cactaataca agaaggtaag
    24661 tatgttaaaa aacaagtcaa gactgcgagc tattttcgtt tttgttggga agatagcgtt
    24721 gttttacgtg attttgatgc tgctcgttta tttttttggt tacctagggc atggtcaaag
    24781 taattttatt tataatgaat tttaggagat tgtctgatgg ttaacgatat gattgaaaca
    24841 attgagtatt ttgcacaagc acaaccggat tttccagttt atgattgctt gggagagcgc
    24901 cgtagctatg ggcagctaaa ggaggactca gatagtattg cagcccttat tgagagctta
    24961 aagctaggtg aaaaatcacc tgttttagtt tttggggctc aaagctatga catgctggct
    25021 tcctttgtcg ccttgacaaa gacaggtcat gcttacattc ctgttgatgt tcattcggcg
    25081 ccagagcgtg tcttgtctat tattgagatt gctcagccaa gtcttatcat tgctattgag
    25141 gagctgccgg ttagtattga tgcgattagg gtggttagct tagcagagat agaggcagct
    25201 aaagcagcca aggcagcctt taccatgacc agtcctgtca agggagatga caattattat
    25261 attatcttca cctctggaac gacaggacag ccaaagggag tgcaaatttc gcatgccaat
    25321 cttttaagct ttaccaattg gatgattgag gatgctgagt ttgctattcc tgagagacca
    25381 cagatgctgg ctcagcctcc ttattccttt gatttgtcgg tgatgtattg ggcgccgacc
    25441 ttagctttag gtgggacatt gtttgcttta cccaaggaaa tggtttcaga ttttaagcgc
    25501 ttgtttagca caattgcgga gctgccgata gggatttgga cctcaacacc gtcctttgcc
    25561 gacatggcaa tgcttaatga tgatttttgt caggagaaga tgccaaggct gacccacttt
    25621 tattttgatg gggaggagct gacagtatca actgcaagaa agctatttga acgctttcca
    25681 gacgcacgca ttatcaatgc ctatggtcca acagaggcaa cggtggcgtt atcagcgatt
    25741 tcaatcacta aagatatgat agagacttac acacgcttgc cgataggcta tccaaagccg
    25801 gattcgccta cttatatcat tgatgaagct ggcaatgctc tggagccggg gcaacaggga
    25861 gagattattg taacgggtcc agcagtttct aagggttatc tcaacaatcc tgaaaagaca
    25921 gctgaagcct tctttacctt taatggcatg cctgcttatc atacgggaga tttaggatca
    25981 tttactgagg acaatgtgtt actttatggt ggacgattag actttcaaat caaatatgca
    26041 ggttaccgca tcgaattaga agatgtgtcg cagcagctaa accaatcacc gctggttgaa
    26101 tcagcagtag cagtaccaag gtataacaaa gagcataagg tccaaaatct cttagcttat
    26161 gttgtcttga aggacggggt gagggagcaa tttgcgagag atttggatat taccaaagcc
    26221 attaaagcct ctgttaagga tcatatgatg gcctatatga tgccgtctaa gtttatttat
    26281 cgtgaaaagc tcccattgac accaaatggc aaaatcgata tcaaattctt gattaacgag
    26341 gttaatcatc aatgacgacc ttgtttcatc acatacctta tatggagcct tatggcaatc
    26401 cgatttattt tgtctacctc atcattgctt ttcttccagt tattattggg atctttaagc
    26461 aaaggcgttt ttcgacgtat gaaagctttg tcagcctgat ctttattttg ctcatgtttg
    26521 gtggagagca ctatcagcaa ttgcttgcct ttttagccta tctaatttgg caaaccatca
    26581 gtgttttggc ttacaagcac tatcgtcaaa aggcaaatgc agcgtgggtt ttctatctta
    26641 gcattttagc cagtctattt cctttgattt gtgtgaaggt aagcctcagt ctaacgaggt
    26701 ctttctttag cttcttaggt atttcctatt taactttcaa aagcgttggg atgatcattg
    26761 aaatgcgtga tggggttttg acagatttta gtctaaagga ttttctacgc tttatgattt
    26821 tctttccgac tttttcaagc gggccgattg atcgcttcag aaggtttcaa gaggcttaca
    26881 ccaagcttcc tagtcgtgat gtttaccttg atatgctcaa taaggctgtc atgtatctca
    26941 tgctgggctt tctgtacaag catattatct cttattgctt gggtgggctg ctattgcccc
    27001 ttgctgaaaa taaggctctg actgtaggtg gctactttaa taaagagacg atctatgtca
    27061 tgtaccttta tgggcttaat ctcttttttg attttgctgg ctactcgatg tttgcgattg
    27121 ggttgtctta tttactgggg attaagacac ctgaaaattt caataagccc ttcttatcac
    27181 caaatttaaa agagttttgg aacagatggc atatgagcct atcattttgg tttagggatt
    27241 ttgtttttat gcgattggtc catctattga tcaagcacaa gacctttaag aatcgaaatg
    27301 tgacttcggg ctttgcttac ctgatcaaca tgctggtgat gggactttgg catggcttga
    27361 cgtggtatta tattgcttac ggtctgtttc atggtattgg cttgattgta aacgacgctt
    27421 ggcttcgtaa gaaaaaggaa atcaatcgtc gtcggaaaaa gcaagggctt aagcctttgt
    27481 ttgagggtaa ggtatttcat gctttatcaa tcgtggtcac tttccacgtt gtcttgttct
    27541 cacttctgtt attctcaggc ttcttaaatg agctttggtt tagcagaccg ttacgttaaa
    27601 aaaggagagt ataaaaatgt ctactaaaga aactgtaatt gacttatttg atcgcttgtt
    27661 tatggaagac gtatcagata tgatggacga ggatttgttt gatgctggcg ttcttgatag
    27721 cctaggaacg gttgagctga ttgtagagat cgaatctatc tttaacatta aggtgccaat
    27781 ttcagagttt ggacgtgagg actggaacac tgccaataaa attattcagg gcatagagga
    27841 attgcagcat gcttaaacgg ctttggttaa tcctaggtcc tctaatcatc gcttttggct
    27901 tggtttgtct taccatattc agctttccta ctaagcttag ctattcattg cgccaggaaa
    27961 agtcaaatgc agtggcaatc aatgatagct cctttaaaaa cggcttgatt aaaaggcagg
    28021 ccttgtcaga tcctaactac tgttttgttc cgttttttgg ctctagcgaa tggagtcgca
    28081 tggatagcat gcacccatca gtgcttgcag aacgctacaa gcgctcctac agaccgtttt
    28141 taattgggaa aagaggctct gcttccttat cacaatatta cggcatgcag cagatttcac
    28201 aggaaataac tggaaaaaag gcagtctttg tcgtgtcccc acaatggttt accccccaag
    28261 gcattgatcc tggtgcggtt caattgtatc tatctaatag tcaggtgatt gatttcctct
    28321 taaaagcaaa ggctagtcat aaggaatcac aatttgccgc taaaagaatg ctggacatta
    28381 atccgggagt tgctaaatca gagcttttaa ggaaaattag tcaaggcaag gccttgagta
    28441 gatgggacat tcgtctgctc aaatggcagc aggagctgtc cttaagagag gagtccttgt
    28501 ttagcttcct tggtcgttca acaaactatg aggataggat tttgcctcgt gttaaagggt
    28561 tgcctaaaac cttttcttat gagcgcttga gcgagctagc agccagacgg gctaaggaag
    28621 gaacttcaaa taatcgcttt ggcatcaaaa atgcttttta ttctaagcga attgcaccgc
    28681 aatttcctct ttataagaat tttcagtgcc gtaataatta cactgtgtca cctgagtaca
    28741 atgattttca gctggtattg tcagaatttg caaaacgtaa aacagaggtg cttttcgtta
    28801 ttacacctgt taatcaagcg tgggcaaatt atacaggctt aaaccagagg aggtatcaaa
    28861 aggctgtcag aaaaataaag catcagttaa cctcgcaggg ctttactcgc attgctgatt
    28921 tttccagaaa tggcggagac aagtatttta tggaggatac cattcacctt ggctggaatg
    28981 gctggctagc ctttgacaag gaggttgttc ctttcttaga ggatcaaaca ccaccatctg
    29041 aataccaact ggatccttac ttcctatcaa aggactgggc agatagaaca gcaggatttt
    29101 agggtcaata gaccattaga aaatgaggat tagaattgtt aatgagtatc atcgtcatat
    29161 tgcttatttt agccattgct gttttagtga ttgagtatgg tcaaaagcgg tccttttcta
    29221 gctggctgct tgaaaagatg tttgattatc gtaagtataa gctctctaaa aaggctgatg
    29281 actatgaagg aattgagacg caaagacgtc gtcgcattcc ctaccacttg gataatccag
    29341 aggcggtatt ggggattccc accacagaat atacgattga tggcatgcag gtttttgtga
    29401 tcaatgacca agattctcag gatcagccag tgatttacta tctttatggt agtgtctatt
    29461 tgcgtcgacc tgagacattt cactttaaaa ccattaagca tttgatccat ttaaccaatg
    29521 ccaagctggt gttcccaaat tttgagaagg cgccttatgt cacctataag gagatttacc
    29581 caaagcttgc taaaacttat caggagcttt gtctagccaa tggcgctgcc aaggttagca
    29641 ttattggtga ctcctcaggt ggtggcatgg ccttagcctt ggcgcaatac ctaagagata
    29701 cccaaactgc accacagcca aagcaattaa tcctgttatc tccttggtta gatgttagct
    29761 ttgctaatca ggattataag cattttgaag cagtagaggc ttatttagat gctaggcggc
    29821 ttcgagacat tggtgaattg tgggcaggca gtccagaaga aatgcggtct ccgtatgtca
    29881 gcccattata tggcgattat catgacctgc caaagattgt cacttttgtc gggacaaaag
    29941 agatttttta cccagatatt atgaccctgc atgagcgctt gatggagcaa gggcacttaa
    30001 atcagctcgt tattgctgag cagatgattc atgcttatgc gatcttcccg atacgagagg
    30061 caaggcaggc gcgcaagcag attgccgagc tgattttaaa gaaggagtga ttgttgctat
    30121 aggagtcagt tagccttgct tgtctgatga ggcttgggct tgagatttct agagaagctt
    30181 taaggccttt acttgggctg ttaatgctca ttaaagagga ttataggctt tatactaggg
    30241 cttaggattg ctgttttgct attcaataat attagtttag acttgattga ggaaaggcta
    30301 gttttagtta tggtcctcaa tctttttttg atggtaaaca tgtcaagaca gtttacttgc
    30361 tagggtaata atcctgtgct catttcatga gtggctattt ttatcctaag cttggtggtg
    30421 gaaaaatcag attaaaaaat atgaaatttg ctattgacag ctgtaagcga ttgcattata
    30481 ataaacttaa cttaaacgtt taagttaagt tgaataagct gatttgatca tgcactgcct
    30541 aaatgcaatc aataatctca aagcatttgg tgtagtctag taatcaatga ggcagtttat
    30601 tacggttata caatatttat ttagttcatc cctttaggag gtaaatagct atggcgtggg
    30661 attggaaaaa agcaggtgtt gttggagtag tgtcattggc ttcgatcatg gtattaagtg
    30721 cttgtagcgg aggacatcaa aaagaggcta agcaaaaaga cgacaatacc attgtagttt
    30781 cagttgatga gggctatgca gactacatca aagagattaa gacagccttt gaaaaggaca
    30841 ataaggtcaa ggtcaaggtc aaaaaggaag gtatgattga tacgctagat aagctatcta
    30901 ctgatggacc gacaggtgct tcaccagatg tctttttagc accatatgac cgggttggtg
    30961 ggcttggctc tgaagggcaa attgctgagg tgagcttagg caatgctgac cagtttgatg
    31021 acactgttaa aaagctagtc accataaatg gaaaggttta tggggcacca gatgttattg
    31081 agaccttagt gatgtattat aacaaggatt tggtatcaga ggctccgaaa acctttactg
    31141 acattgaaga gctaaataag gatcctaagt ttgcctttgc ttctgaagac ggtaagtctg
    31201 taggctttct tgctaagtgg acagacttct attatggcta tggcttgatt gcaggctatg
    31261 gggcttatgt atttggagat aagggaactg atccaaagga tttaggtatt ggtaatgctg
    31321 gtgccattga aggcttagac tatgctaaga aatggtatag cgtatggcct caaggcatgc
    31381 aggatactca aaaggctgga gattttatta cagagcaatt cacctctaaa aaggctggtg
    31441 tgattattga tggaccttgg gctgctgcct catttaagga ggctggtgta aactttggag
    31501 tggcacaaat tccaagctta cctaatggcg gtagctatca agcctttggt ggtggtaaag
    31561 catgggtgat ttcaaattat tctaagaata aaaagctggc acagcaattc cttgattatg
    31621 tgacaaatga gaaaaaccaa aaagcctttt atggtaagac acaagagatc cctgccaatc
    31681 tagctgctcg cagctatgct gcagaacaag gaaatgaatt gacaaaggcg gttattgggc
    31741 aattctcaaa tgctcagcca atgccaaata ttccagaaat ggcagaagtt tggggaccag
    31801 gtgcgaacat gttctttgag gtagcagcag gcaagaagac tcctgccaag gctgctaagg
    31861 aagcagctaa aaccattcaa gaggctattg cacaaaaata cactgaataa cataaaaagg
    31921 gaggctggga taaaggtatc ctagtctcca tcttgttacc tatagtatca gagtgggcga
    31981 tgaggagata ataataaaaa gtagtagtga ctagcttgtc ttgtttccca tcttgtccta
    32041 ataagagtat ctgataagac tgatgaacct agggaggaaa aaatgaacac agccggaata
    32101 ctgcatattc cagattctag atattgcttt gccttatcaa caaaggagct tgtgattcgg
    32161 ttgagggttg caaaggagga taacgatata gcggtgacgc tggtttatgg acctaagtat
    32221 cattatcatg agtatcaaaa agaactggcg atgtatgctg cttataccga tcatacccat
    32281 acctattatg aaatcacctt aagtcttgat gatgttagat tggcctatat ttttaagctt
    32341 gagcaatctg gtcacaccta ttactttagt gaggatggct tgaccacaag ctatgatttt
    32401 tcaaatggct tttacaactt ttttcaaatg ccttatatta atgctgtaga cgttcatcag
    32461 actgtccctt gggtgcacaa tgctgttttt tatcagatct ttgttgatcg ctttcatcgt
    32521 ggtgactttg aaaaggacga tagctatatt aatatggctt ggctggatag gccaactcct
    32581 aatagctttg ccggagggga tttgaagggg attacagata agctggaata ccttgaggat
    32641 cttggtatta atgtcattta cttgacaccg attttcaaat ccatcagtaa tcacaaatat
    32701 gatattagtg actactatgc tattgacccg atgtttggga catcgcttga tctccagcaa
    32761 ctaataaacg aggcccacca aagagggatt agaattattt tagatgctgt tttcaatcat
    32821 gctagcagtg attgcgagcc atttcaggac gttttggcac atggtagtgc ttcttcattt
    32881 tttgattggt ttatgattca aggagatcat ccttctgtag agctagctaa ttacgaaacc
    32941 ttcgctgatt gtcactacat gcctaagtgg aatacctcgc atcaggctgt tcaggattat
    33001 ttgattgaga ttggtcttta ttggatcaca gagtatcata ttgatggctg gcgattagat
    33061 gtttctgatg aggtatcgca tgatttttgg agacgctttc gaaaggctgt taaggcagtc
    33121 aaatcagatg cgatacttat tggagagaat tggcatgatg cttatcccta ccttcaagga
    33181 gaccagtatg atggtattat gaattacgcc tttaccaagg cttgtctcga ttattttgca
    33241 tttgatgcga ttagctcaca ggaaatggct gaaagattgt cgcatatttt aatgagaaat
    33301 acttggcagg tcaaccagat gaatctgaat ttactggatt cccatgatac gcatcgcttc
    33361 ttgactcagg tgaatggctc taaggacaaa ttattggctg gcttagccct tttagttacc
    33421 tttatgggca taccatgtat ttactatgga acagagcttg cgatggaggg aggttatgat
    33481 cctgactcta gacgtagctt taattgggac agcagcactt gggatatgag cttttggaat
    33541 caggttaagg acattatcag cctgcgtcgt catgcggtta tccaatttgg aagcatttcg
    33601 ataacctccc atgatgactg cctttgcgta aagcgtgaat taaacggtca atcgataaga
    33661 ttgctggtta ataatggcgt taagccatat cctattgaga aaggaggttc tgtgcttgtt
    33721 tctaatggtg tagataaaga gacatttgag ctactccaga acgggtttgt tgttagctat
    33781 taatatggcg ttttatcaaa ggaggttaag gatgaagcgt attactttaa catgtcgtaa
    33841 agcattaaca gtagctatgg cagcggttac cttagcaatg tcaactaaca gtgtctttgc
    33901 tattgaaaat actgcggtgt ctaataaggc tgatttttct actgacacga tttatcaaat
    33961 tgtcaccgat cgttttcatg atggtaatgc tgctaataat ggaaatacag atgtatttga
    34021 taaaaatgat cctaaaaaat atcatggggg tgattgggca ggtatcatta agaaactaga
    34081 agatggctac ttaaccaatt taggggtatc agctatctgg atttcatcac cagttgaaaa
    34141 cattgatacc attgaccctt caaatggcag tgcagcctat catggctact gggcaaagga
    34201 ttttttcaaa gcaaacagtc actttggaac aatggaggat tttaaaaagc tcattcaggt
    34261 ggcacatggc aaaaacatta aagtagttat tgattttgct cctaatcata cctcaacagc
    34321 agaatataat ggcttaacct tccctgagga cggtgcttta tataaggacg gccagctggt
    34381 tggtaaattc agtcatgatg atcaaaagat tttcaatcat gaatcatgga ctgatttttc
    34441 aacttatgaa aatagcattt atcattccat gtatggcttg gcagacttga acaatctgaa
    34501 tccaacagtt gacgattatc tcaaagaggc tattgataaa tggttagaaa tgggcattga
    34561 tggtattcgt gtagatgcgg tcaagcatat gtcacaaggc tggcaaaaaa attggttgag
    34621 tcatatctat gagaagcata atgtattcgc ctttggggaa tggtttgctg acggttcttt
    34681 taatgatcca ttgatgacta aatttgctga tactagcggc atgagcctgc ttgattttag
    34741 gtttgctaat tctgttaggc gcctgtattc tgatttatca gcgaaaatgc aagattttta
    34801 caatatgatt gtagctacgg aaaaagagta caaggaagtt tcagatcaag tgactttcat
    34861 tgataaccat gatatgaccc gctttgctac tctagtcaat cataatcaga cagctgttaa
    34921 tcaagcctat gctttactgc taacatcgcg tggtgttccg aatctttatt atggttcaga
    34981 gcagtatgct acaggtgcta acgaccctga aaatcgtggt gatatgccaa cctttgataa
    35041 gaattccact gcttatcagg tgattagcaa actagcacca ctgcgtaaga aaaatcaagc
    35101 cctggcttat ggtacaacac agcagcgctg gattaatgat caggtcttgg tctttgaaag
    35161 aaaatttgga aatgacgttg ctttagtggc tgttaataag gatcaaacaa atggctacac
    35221 aattagtggc gctaaaacgg ctttaccagc tggtaagtat gctgatgaat taggtggctt
    35281 actgggcgga aaggaattaa cggtatcagc tgatggtaat gttgaggcat ttgagttagg
    35341 tgcgggtcag gttgcagttt ggacctttaa agggcaacat gagacaccgc agataggaga
    35401 cgtagacgct tcgtttggcg ttgcaggaaa tactgtctct atttcagggc aaggatttgg
    35461 tagtgctcaa ggtcagcttc attttggtga tagcaaagca gatattgtgt catgggacga
    35521 taccttgatt caatttaaga tacctgctgt agctgctggg aaccatgata ttaaggtgac
    35581 cacatctaca ggacaaagca gtagccctta caaagccttt gaagtgttaa cagataagca
    35641 aattccagta agattggtgg tcaataattt caacactgta ttaggtgagc agctttatat
    35701 cgttggtgat gtggttgagc ttggggcaaa tgataatcat aaagctttag ggcctatttt
    35761 taatgcaaca cagtcaattg cgcagtaccc aaattggttc tatgatgtca atctgcctat
    35821 taacaaaacc attaactgtc atcttgtaaa gaaggatagt tctggtaaag tattgtggac
    35881 tagtccagaa acctatacca ttaaaactga tagcaaggct caaaccattt cattgaaaaa
    35941 atagttgcgt tatctgtgat gttatttaat actctatgaa ggaggagaac cataaaaggg
    36001 tgatagagag gaatgacaaa tgcttaagaa tgaaaaaatg aagaatccac aaaaagccat
    36061 gtggctttca ataatccctg gtctggggca actctacaat actcaaaagg taaaaggctt
    36121 tattttgctt cttgtgtttt taggtgagct gctagaggct ttctttgttg gtattccggc
    36181 tcttgctggc ttgtacagcc ttggtagtgt accaatggag gatcattccc tattcttatt
    36241 gattaaggga gctatgcagc ttatcctatt tgccttgttt ttgatctttc atttggctgc
    36301 tatgcgagat gctagactag tggcaaggga gatcaatgca ggccatagca tttcattaac
    36361 cttaaaggag atggtacaat ccatctatga aaagggcttt ccttatttgc tgattattcc
    36421 agcctacttg gccatggcct ttgccattgt ttttccggtg cttgttactt tattaattgc
    36481 atttacaaac tatgatttta ggcatattcc tccctataaa ttattagatt gggttggcat
    36541 taagaatttt aaaagcattt tagagcttag cacctttaag tcagcctttg gctctgtgct
    36601 gtcatggacc ttgatttgga ccttggcggc aacgagtctc cagattgtga taggaatagc
    36661 gactgctatt attgccaacc agtcctttgt gaagtgcagg cgcatttttg gggtgatttt
    36721 cttgctgcct tggggggtgc ctgcttttat ctcgatcatg agctttggta atttctttaa
    36781 tgattctatc ggtgctatga atgttcaggt cttaccattt ttagaaaagt ttgtgccatt
    36841 tgcagatttt gggattatcc catggaagac agatcctttt tggacaaagg ttgcggtgat
    36901 tatggttcag ggctggctgg gctttcctta tatttatatt ttggtgtctg gtattttaca
    36961 atcaattcct gctgatttgt atgaggcagc aacggttgat ggtgcaacag ccctgcagaa
    37021 gtttcgccaa attaccttgc caatgatctt tgctgtcgca gccccgacct taatctcgca
    37081 gtataccttt aattttaata acttctccat tatttatctc tttaataatg gaggtcctgg
    37141 tacagttggc ggtggcgcag ggtcgacaga tattttgatt tcttggattt acaagctgac
    37201 cacacaaacg tcaccacagt tttccattgc ttcagcggtg accttaatca tttccttgat
    37261 tgttatttct gtatcattga taacctttaa aaaattcaaa gcctttgaca tggaggatcg
    37321 ctaaatgggt aggaattatt tgccacagtc agtgaagaag aagcgcttgt tagctcagct
    37381 gttgacttac agctatttgc taatcctgtc gatcatcatc ttatttccaa tcttggtgac
    37441 cgttagctca gcctttaggc caggaaatac aactgccttt agctttcata ttgatgggcc
    37501 ttggacctta tcaaactttg agacactctt tcaggacacc tattacttaa gatggtactg
    37561 gaacacgtta gttgtcgcct ttttcacgat gctgatccag gtgacagtca ttacgctgac
    37621 aggctatgct tacagccgtt atcacttttt tgggcgtcaa aagagtttgg tctttttctt
    37681 agtggttcag atggttccga caatggctgc cttaacagct tattttgtga tggcttggtt
    37741 gtttaatgct ctgaatcact attggttcct cattctgatt tatgttggag gaggcattcc
    37801 gatgaatgct tggttgatga aggggtattt tgatactgtg ccttatgatt tagatgagtc
    37861 agctaagcta gatggctctg gtcactttag gaccttctac caaattgtat ttcctctggt
    37921 tcgtcctatg gttgctgttc aggccctatg ggcctttatg gggccatttg gtgactttat
    37981 gcttgctaag tttctcttgc gtgaacagga gcattacacc gtagcggtag gtcttcagtc
    38041 attcatcact aacgacgcta gggatcctaa ggtcacattg tttgcagccg gggccatttt
    38101 aattgcagtg ccaatttcag tgctattctt ctttttacag aagcattttg tttcaggctt
    38161 aaccaatggt ggaacaaagg gttaatttat ctttcaagga gcctttatca tgactaatga
    38221 tcgatttcct atttcttaca caaccattat tttttctcct aaaatgatat ttgctcgttg
    38281 cagtgccttt ttgtggtggc agaatgtgat tttagtgatc tttctaaatg ctctggtgtt
    38341 aatgccgatc acgctgcatt atgcaagctt gaagagctat cccttagagc acatagttag
    38401 taatggttta gactccttga cagaaaaaac ctatcatgcc ttgacacaag gcactatttg
    38461 gcatgatcgc tatgatggaa aaacagtcct tatagaggat actgatgctg ttgttgctgt
    38521 attgccaaca ccagaaatag tagaagagct aaagaaagat caaagaagcc agctgatatt
    38581 aacagaaacc tcatggattt taagctttcc tgatggtcaa aggctaactg ctaaggttaa
    38641 aggcaacaag gaaaggctaa cgcgcttaac ctctctagag gctgtcaagg cctttgttaa
    38701 tcagcaatgg tacaatagca atcgtgccgc tgtgcttgcc tttttgctgc tagtggctag
    38761 cagtgtggtc tatctaggag ccggtttagt gatcggaatt ggctcgttat cactgttatt
    38821 aacaagatct gctagattat tttcactcaa gagctactca gaatgcttgg gtttgctagt
    38881 gaattgcttt ggacttccta cgcttttagc agtgcttata agtttttggg tgcacaatcc
    38941 tattgttatc atgaatagtc aggtctttgg cacactgctc atgctggttc tagtctttta
    39001 caaaactcag tttagagatg aggagcaagc actagcttag cccttgctga catcaaaaaa
    39061 tccctccc
//
LOCUS       DARYLJ010000017        38546 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYLJ010000017 DARYLJ010000000
VERSION     DARYLJ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38546
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            101..316
                     /locus_tag="TU746_000779"
     CDS             101..316
                     /locus_tag="TU746_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL0891144.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            316..1179
                     /locus_tag="TU746_000780"
     CDS             316..1179
                     /locus_tag="TU746_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891145.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1252..1746
                     /locus_tag="TU746_000781"
     CDS             1252..1746
                     /locus_tag="TU746_000781"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0891146.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            1750..2160
                     /locus_tag="TU746_000782"
     CDS             1750..2160
                     /locus_tag="TU746_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL0891147.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            2120..4597
                     /locus_tag="TU746_000783"
     CDS             2120..4597
                     /locus_tag="TU746_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL0891148.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            4599..5624
                     /locus_tag="TU746_000784"
     CDS             4599..5624
                     /locus_tag="TU746_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL0891149.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            5590..7878
                     /locus_tag="TU746_000785"
     CDS             5590..7878
                     /locus_tag="TU746_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0891150.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSKVSYRTLTDDEKYDNNQN
                     DKGKNYNDYVKNPKSKNKRYKNYVKDTFSKERMKSENQKKYVRSNFDDEEFTRNKDTK
                     NNLFQDVNNKRKTTDKNSSRKRKGKFENKEKKISKLQQKKQRQEQKLKNKGIDGKSQS
                     AKSAVIATGMAKRYLESGKEDNAGVGTAYKVTDQVENISRKIYYHGKKKNLKRQKKIT
                     KLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQFFKRRQYKNQIQKKYKDSVKNR
                     IKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFMLFQAGSMMMNMGTGMVSNTVST
                     TYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGYDEYIIKGKEKIGHNVHELLSY
                     ITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIRYRTVTSSYTDADGNEHTESHE
                     EPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYETLFLTQGNMGEVFGNIDLINSN
                     GGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGFIGGNACDMY
                     RNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVGIYIGDGKVMDNIGHIRVTTLD
                     DWIATFCKHHPVGFGFPPSVQK"
     gene            7891..8178
                     /locus_tag="TU746_000786"
     CDS             7891..8178
                     /locus_tag="TU746_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0891151.1"
                     /translation="MNKKYRKNIEKQKDIQKKIEELQLKQEMLKEEQEEMENIEVLKE
                     YRSIDISIDDFLEMMRRYKKEEKQEKMKLQEMRNTENHNNMEENHENQMEE"
     gene            8183..9619
                     /locus_tag="TU746_000787"
     CDS             8183..9619
                     /locus_tag="TU746_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL0891152.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            9872..10465
                     /locus_tag="TU746_000788"
     CDS             9872..10465
                     /locus_tag="TU746_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL0891153.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     IQSYSSYKERDIHSLYDIAMKMGIENKVREVMEVAYE"
     gene            10458..11300
                     /locus_tag="TU746_000789"
     CDS             10458..11300
                     /locus_tag="TU746_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL0891154.1"
                     /translation="MNKAKLTALCHKVSKEVGLSFNAVMLYYFLESILKKLAGSKYSE
                     RFIFKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYEL
                     QNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEI
                     IIKAYPIETMLAEKIQTIYARGFLNSRSKDYYDLYIIYKLKDKDVNVEILREACRKTF
                     SYRKTEFDIGKIIDLLEKLKINEAFLKRWQAYSRKNLYAKDITFEEVLDNGIKMVEKI
                     KNEN"
     gene            11472..13184
                     /locus_tag="TU746_000790"
     CDS             11472..13184
                     /locus_tag="TU746_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL0891155.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            13188..13739
                     /locus_tag="TU746_000791"
     CDS             13188..13739
                     /locus_tag="TU746_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL0891156.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            13781..14527
                     /locus_tag="TU746_000792"
     CDS             13781..14527
                     /locus_tag="TU746_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0891157.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            14544..26471
                     /locus_tag="TU746_000793"
     CDS             14544..26471
                     /locus_tag="TU746_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL0891158.1"
                     /translation="MNDLIKNYENIPDEMKKEKRWCLYKIIQRDGKNTKLPLMPNKEP
                     AKSNDKATWNSYEDCIMALKHNVGEGLGFFLGDGYIGIDIDKVSDDIMEYNTNHHVSS
                     MTADFLREVSTYAEISPSKTGLHFIGKGEVPGERKRYKNLEIYDKDRFFTVTGNVIKD
                     RDRSKIESIDSELKPLYEKYMPKTNKISAENKRSPTVTSYNGDQDILEKLFDRGYFSY
                     AGEDLRQIYYGNYERYFNSQSEADFFMLQRLLYYTGNVEMAISFMESSGLKREKWYKR
                     RGNTDYIHYIADKAISSINQFYDWEKVYTSKEKIEEKRYENKKKKEGDTVPRYEFDEV
                     KQILDFAKEEFKENIDRYETYLKVMGNNYKYPYFNQLSIYTVNENATACAEYDYWKSI
                     GRNVNRGEKGIPVLDIEREKIKYIFDASQTVSLNHNISEVKLWEYSNNKHVAALDTLI
                     DVFKEKNSNLIFSTEDKINTIVSLYTKQLLNKVLNSLSDETLKENKKVQILHFLEESA
                     KVSVYERMGVAFSGDIEKLEMLSNVSSMQDIDRLLFFTSNNVKRILMDISREISKVEE
                     REKISEIQKREQTNSIAERYTNVTDEINGNTEIIENEKERNEGGLEDERNRSIGEEGV
                     HPRKRDLYTDRKRESIRETGRDLQIGENGGWSGSISSEYENAGENKRKQTEPIWQGET
                     EISQRGETRGISDYADGRNFNGSFDRYSGTSGGFPEYRRAEDERSLENDHRNAGSGLS
                     EIHRTEEELGYDTNKNGYGTDHLGIDEYRKENIQKIEQNHVENEEKEVERTSFSFAQN
                     VGVQGRFELPMQQEEIGAVLIHGGNEDNLHLKVLAEYSKEKSMEELADFLQKTFQGGN
                     GYELNGNKVCAWYEMDGIHLSNDVSSRENPMQILPWKDAAIRIGELIDYGKYSTNVEV
                     AEAFSFERAELSEKLWFLKGDLSDEVKNQFLPILNEKQRNGYPEKTEYLTKKLEDKEF
                     RVNLKEEYIEFFKAYKENSNVLRFHNHDLDDISKRLDDLELPRKEFTSTLIELPAIQG
                     FITEDEIDRYLSSGSNVSGGKERIYNFFREARTTEERANFLKDEYGTGGQTHALSRAR
                     GSSEWHDAKGIKLEKENCKDIILKWNQVVKKIDNLIENGKYIQEDVYTEQESIKTEEE
                     YFDEDTYTEQNSKENEQDWQREQEILLIQDEREVSYEEAEEIYERQAEIEHNAFATGV
                     ENNISSTQSNKDYWIVEFNEGSNLIEKNYAGEVVTKKLLDEIKVLDEKIRVHNKTVGE
                     DEYGEMTDEWVGYSKFYFDHIVDGKVEEHFRMDIGDGNEVNQRDFQYLYEQIEPEKEN
                     KEYGMDSIDSVIKDILEKESMTVVSSKDDYIKLFPYFRNFVYTDGLRLDEYNPFEDDE
                     NISDLIRLTFFQNNDGEYRVVYNNADSLLYSSNVDYFLEKIEAEKVRLEDNIAEIPNE
                     DKIAVKVGNYYAVVEKERVKDISLEETGVRVYPKENNFEGKIYPLYRGSTFEESAKID
                     KLFDEIAIGMKEVNLTDLNDVFYLENQGLYEISSDRVTEEKAGYDFEVASFNEQFPDY
                     YNDIYVYNRNLKIDGANQNIAYINRENEIHFNVNLPEEEKAKVLEIRDKKEVLSTLIF
                     KDVKEVGEYQFHPQSEEFILNELSISEEKLKAPEHITDKIDKKEGYEAELVLDMKNKE
                     LRQHLRYNGYMLSSNVAVSYDSYKAILKNLSYLLDDNHRNIMLTGYVNEQIEKDKAKE
                     ERKEPVYQEGMNVRYQGKEYIISEIQDYKTYKTIKLDDSEGYLNGFITGSEIIPFRNE
                     RELDLEIISTTEKLQEQSINGEDLILLDIEEYNKKGLSVIFQNKEYEITGNNFNPVGM
                     SRLQLVSNTEKLMTEISYTPQRPVANLYAKKDLLERFNLNEKNSEKSIEAKQMSLTDI
                     FEEQDTTKGKEEISSEKERVPVNIGAKVIYQGEEYTVSAFEYNNILEKNDIWLNPVSK
                     NNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSELLHHSLDVINDKGSVIANQFIVK
                     VDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQIDGDGNNLKLTKHKKETIDKKLKS
                     YHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEYEEKLKEEERYAPDDKYLGGIPP
                     INYKITKEDEILPPSERLKNNIEAIKVLKEIEERHSHATKEEQDILSRYVGWGGLSDV
                     FDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAFYTPKIVIDSIYQAVLNMGFESG
                     NILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGRIASRLYPNAKIQIKGFEETTFS
                     NNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFAKTLDKVRSGGVVAFISSSGTMD
                     KKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVTSDIIFLKKRDRLVKLDEEWVKL
                     GTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLACVADENSTLKEQLDTAIKNIKG
                     SYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYFRENSVMQKLNLNKNDEEKVRAY
                     LGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDEFSKKYGILNSKANKKLFREDAN
                     YSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHTDNLTEALILSISQKGKVNFEY
                     MEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSSAIDLGDFSRSYVTADEYLSGN
                     IRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQGSETLKKELSSLNYQRQKLLEVM
                     PKELEASEITVRMGATWIPEKDYKSFMFHLLKTSASNRWNIDIKYTNFTGEYRVEGKS
                     IDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYDQVIDENGKKSSVLNQKETMLAR
                     SKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIRLREYDGSNLTFDGMNPEIELRP
                     HQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHIVEQFG
                     REFNELYPAANILCATEKDFTPDKRKRFCSRIATGDYDAVIIGHSQFEKIPISKQRQE
                     YELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKGLEAKLKKLNDDYRKDDVVTFEE
                     LGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQKSSDMLMKCRYMDEITGNKGIVF
                     ATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSWASTFGETVTAIELNPEGNGYRS
                     KTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNAHYETIKTKPTEEQKQILETFSE
                     RADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINPLLPDDPNSKVNTCVNNIFSIWD
                     KYRDEKSTQLVFCDMSTPSSEFNIYDDIKEKLTKMGIPKNETEFIHNAKNNKEKDKIF
                     DKVRKGEIRVLLGSTQKMGAGTNAQNKLIATHDLDVPWRPADLEQRKGRIVRQGNEND
                     DVHIFRYITENTFDAYLFQTLETKQTYISQIMNSKTPVRVAEDIDEATLNYAEIKALA
                     TGNPLIREKMDLDVEVSKLKMLESNFKSNLYKMEDKVVKVYPKEIKSLKEKIENLKKD
                     IEKVEPYREEKLEKYDQTTLENMGENEKQVGIKADKEAISKFTSLTLNGKKYTDKKQA
                     GEFLINKIKGIKKLDDFRSEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENHYGEFG
                     TDEIGNITRMDNVLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLKEKTLR
                     LAEVNNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFPDLTDI
                     GLAYTTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELIQIKTN
                     IGFWDFNELVYVDEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFRDSKVQ
                     SFGDLDKKEKASVMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
     gene            26952..27911
                     /locus_tag="TU746_000794"
     CDS             26952..27911
                     /locus_tag="TU746_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0891159.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
     gene            28069..28554
                     /locus_tag="TU746_000795"
     CDS             28069..28554
                     /locus_tag="TU746_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0891160.1"
                     /translation="MIGLVILFIALIILYLGVILFAGATFVKISLFALDKLVVFIASW
                     YYTHHYFSVKFSSGYAIYFWDILAAILVVIIYSILFQFIHKKFRVLGKILNLAISFFS
                     SMIVYCLLVNGFITTEKSYFLPLLNNSFMNQVVNYIIIAIISLVVWKRREDYLVETHD
                     K"
     gene            complement(28664..30037)
                     /locus_tag="TU746_000796"
     CDS             complement(28664..30037)
                     /locus_tag="TU746_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL0891161.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVASD
                     RQQLLDHIKQIEKEMKSIYSVIENKNTISENQLTYDMYIKDKENKAFYEEYKSQIIAY
                     ETAMKSLKNSKLQTLSIKNLSDKYMLLEQEKTTLMGEYSSQNSMLRKLQQAKKNTDLY
                     LDNSLEK"
     gene            complement(30037..30405)
                     /locus_tag="TU746_000797"
     CDS             complement(30037..30405)
                     /locus_tag="TU746_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL0891162.1"
                     /translation="MANRTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILE
                     KDIFVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIY
                     FLRKKLYELGNFGTSGTEEI"
     gene            30942..31322
                     /locus_tag="TU746_000798"
     CDS             30942..31322
                     /locus_tag="TU746_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012797113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL0891163.1"
                     /translation="MNKIYHKEYVEQNYLENIYTLYLERDEVRNIDIVDKLGVARATV
                     THMLRNLEKKGYIKYGDDKIVRFTSKGRTLAVELYEKHIYLTQVFKHIGVDEKIAEIE
                     ACQIEHIISKDTFNKIKKYFEDKI"
     gene            31551..32300
                     /locus_tag="TU746_000799"
     CDS             31551..32300
                     /locus_tag="TU746_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL0891164.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPESVIKAIEEFVYSNENI"
     gene            32287..32970
                     /locus_tag="TU746_000800"
     CDS             32287..32970
                     /locus_tag="TU746_000800"
                     /inference="COORDINATES: protein motif:HMM:NF013786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HEL0891165.1"
                     /translation="MKIYRIEISDKKELRSLIDISRLLIFFDMVLVTSNTSEFMIKDL
                     KNFLKEEEIEKLDAYKSEVAKINFAVSRSLLNKVFEMILGVPIENIVSFRDKHNKPYI
                     ENKSGVKFNISHTDGFVVIGFSKKELGIDIEKVNDGFAFEDILENCFTSREIKNIGSN
                     IPMFYRYWTAKEAYLKYEGYGLIRNPKEIEVIYIDNQRIKIEDKVKRSNKDLIAFSIS
                     SKYFGAICI"
     gene            32979..34562
                     /locus_tag="TU746_000801"
     CDS             32979..34562
                     /locus_tag="TU746_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL0891166.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEAVAYISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYK
                     NFSSLIENDCFYKYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNV
                     NQESVYLASLPIAHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGF
                     VPAIANICMDYLEYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGL
                     ILTTNEEDNDKIRWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYN
                     LPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTH
                     ENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYID
                     AWPLTALGKIDRNKLKETF"
     gene            34577..>38546
                     /locus_tag="TU746_000802"
     CDS             34577..>38546
                     /locus_tag="TU746_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL0891167.1"
                     /translation="MELNNIKERAKELVKDWLKSIFVEKVVSENENLIEKGLSSIQVM
                     QLSGKLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQSDESKFDLTD
                     VQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDG
                     KQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFS
                     DEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQNGIGESIND
                     ADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETIKDIAASYRS
                     TPSMVLLTAYALVLERWCNQDKFFINIPLFNRDLENENLKEMVADFTNILLVEHEAVD
                     DSNFLDNLKRINKTFLENVSHSEYNGVQVQRDISKKQGTSVYIAPVVFACNIDYPLET
                     EFSRKNLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYE
                     LIISLTQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRV
                     AIIDSETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFT
                     GAAYVSIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVA
                     KLKQPVEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMV
                     SAIDFDLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMI
                     VTMAEGKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHL
                     NVPRKIPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEE
                     LTNKKYFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVF
                     ENIKKAIALIVKDGNVNKLVGFAEIFDCKESNQMLLNSDFEKETEEYKKQKDEYINFI
                     DELNFKVNRIIFNVIRKCGVFSDESYITLEDIIKKINPIDSLKNLIKSWIYNLCEEGL
                     IKRNDSNNYCISKFMCDDEKYDVIKTKEKDIELNRYLQVLETYLLEMIQGKVNPINFF
                     YTTNPELSPISLSKLLPWHEDVMECIFNYIEIDVDGNDKENIILDYDSKNDFLSQRID
                     EISDRCVHLHFDKTLNVINKVSGDFKNENDFESLENKLDYIVAFNSIHRTVNIKETMK
                     KLRNLLTNNGKLIVVEPKERIRIQDITTSILNNFAGYNDNIFNVDEWNSIFYDANLNC
                     CKQ"
BASE COUNT        15112 a         4657 c         7808 g        10969 t
ORIGIN      
        1 aactttaaga aaattgaata gcaaaagttt aacgattgga agagaagatt tccagtcgtt
       61 tttttatgaa aataagtaaa ataatgagga ggaataaatt atggattttt ttgtacaggc
      121 agtaaatgtg cttaaaattt tggttatggc aatcggtgca ggacttggtg catggggagt
      181 tatcaactta cttgaaggat acggatcaga taatcccggt gccaagtcgc aaggaatcaa
      241 gcaattgatg agcggtggag gaattgtttt aatagggctg aaactaattc cgctacttgc
      301 taatgtcttg agataatgtt tgatttattt ggaaagatag aagagttttt caaggatatt
      361 atgattgata ttattaaaga taatctttct gcaatgcttg tggatattaa tgataaagta
      421 ggaaccgttg caggagaagt gggaaagact ccgagttctt ggaactcgga ggtcttcacc
      481 ttcattaaat caatcaatac caatgttgtt ttacccatag cagcgataat tctaaccgca
      541 atactttgca tagaactgat tcaggtggta atgagaaaaa attctatgca cgatacggat
      601 acctttgaat tttttaagta cattattaaa atgtggatag ctgtatggct tgtgtctcat
      661 gcgtttgatt tttcaatggc agtctttgat gtggcacagt ccatgatagg aaaggcagca
      721 ggtgttgtgg ggacaagtgc gaatatcaca ccgggaaatt ttgatgctat ggtagaagcc
      781 cttaaaacaa aggaacttgg aacactcatt gggattgcac tggagacggg attagttaaa
      841 ttttctttaa cgattctatc aatcttaatc actgtaatcc tatatggaag aatgattgag
      901 atatatatct attgctctgt tgcggcaatt ccattttcta cgatgggaaa taaagaatgg
      961 tcaaatatcg gaacaaacta tataaaaagt ctatttgccc ttggacttca gggacttttc
     1021 atcctaatat tttttggaat ttacgcagtc ttagtcaaaa ccgtaaactt tacggatatc
     1081 cacacaagta ttttacaggt attggcatat ggattgattc ttggagtaat gatgatgaaa
     1141 tccggaagta tagcaaaggc gattttaaac agtcactaaa ggactttagt tcaaaatgag
     1201 caaaagttga tgaaataatc agaacaaaaa atataattat tggaggtaag aatgaataaa
     1261 ataaataaaa aaacaaggat tttgatagga gcaggctcag ccctttctat cgggacaatt
     1321 attacagtgc tattaaaaaa gaaaacgaaa aaattatccg atcttgaaga agatgatttt
     1381 gactttgatt ttgatgaaat agaagaagat tcttgtgtca acgataaatt tgctacagaa
     1441 aatgataaag atgatacagt aaaaggagaa atagattttt tagtagatga atcaaagacg
     1501 gagaacgaaa agcaagaaga gtttagagat ttatcggtaa aggtaatgga tcttcttcta
     1561 aaagaagtaa tttcaatgag tgaaacctta aatttggtaa aaagagatat tgatagaata
     1621 ggtgaagtaa aagcattggt tgaagaactg gaaaactgta aagaagaaat tatctcactt
     1681 tgggagcaca tggaaaagtt atccgattta agagaagaaa ttaccggcaa aaagaataga
     1741 ggttaggcta tggcttatgt aaagatacca aaagacctta caaaagtaaa aaccaaggta
     1801 gccctgaata tgacaaaaag gcagcttata ggttttagca tagcagggct tatcggtttt
     1861 cctgtatata tgctgtgtaa aaattttctt agtacagata tttccatgat tataatgagt
     1921 atagtagttc tacctgttct ttttgtaacg ctttatgaaa aggacaattt accttttgaa
     1981 aaacatttag catatatcct caggtttcat aaaagtaaaa agatcaggct atataaagcg
     2041 aggagcattt atcatacaga gagagcaaaa aagcaagata taggaaataa aaataaggca
     2101 agcggaagga ggaaaaaagt tgaacaaaga caaaagaaaa aaacaggaac aacgaattaa
     2161 aaaggatgag ttggagctta ggaaaaatag aaaggagcta tccgaactta aaaaaacagg
     2221 aaagaaaaaa acaaagtcta aaacaaaagg gaaatcatcg aagaagaatg ggtggtttcc
     2281 tttttttatg aaagaggaga aaaaagaaac cgtacaggat accattccat ataagcgaat
     2341 gttaaaagac gggatttgtc aaattgaaaa gaataagttt aataaaacca ttcgattttt
     2401 ggacattaac tatcgcttaa tggaagaaat agaccaagag ggaatatttt cggaattttc
     2461 ttcttttcta aatttctttg actcatctgt ggaagtggag ttcagctata tcaacagtat
     2521 cggagaaaat gaagaaatca ataaactgat tgatattaag gaaaatatag atgattttaa
     2581 tgaaattaga aacgaatata gacaaatgct cttaaatcaa agcagcaaag ggaataatgg
     2641 attatcaaag agtatgtaca ttacctttac catagaggcg gaggacttaa agcaggcaaa
     2701 aagtagatta gagcgaatgg aaatggatgt attaaacaac tttaagcaga tgggagtgaa
     2761 agcctatgtg ttagatggag aggaaagact taaaacaatt catgacattt taaatccaaa
     2821 tgataaactt gttttttcct ttgaggattt gaaatacagc ggactgacga ctaaggaata
     2881 cattgtacct ccgtctttta acttttccaa gccgacgtat tttaagacag gagaagtctt
     2941 tgcggaagta aattttttac agcttttagc atcagatatt aaagatgaga tgttatcaga
     3001 gtttttggca ttggaagaaa atatgattgt tacttttcat atcagagcaa tcgaccagat
     3061 ggaagctatt aaacatgtaa aaagaaaaat aacggatttg gataagatga agcttgagga
     3121 aaacaaaaaa gctattcgtg cgggatatga tatggatatc ttgccaagcg accttgtaac
     3181 ttatggtgca gaggcaaaga acttgctatc agaactacaa aaccatgatg aaaagatgtt
     3241 tctcataaca attttattta tgaacacgag taaaagtaag gggaaactcg ataatacggt
     3301 atttacctta aagtccattg caaatagaca taattgtagt ttgaaaaacc taaattatag
     3361 acaagaacaa gggcttgttg caagccttcc acttgggata aatgaagtgg agatagaacg
     3421 aggacttacc acaagtgcag cagctatttt tataccattt acaacagaag aactctttat
     3481 caagggagaa agcctatatt acggactaaa tgcactaagc agaaatatta ttatggcgga
     3541 caggaagaaa ttaaagaacc caaatggtct aatcttaggg acaccgggtt ctggaaagtc
     3601 ctttgcagcc aaaagagaga ttactaatgc gtttttgatt acagatgatg atattatcat
     3661 tgcagatccg gaagcggaat attctccgct tgtagaggca ctaaaaggac aagttatcag
     3721 aatttctccg atttcaaaag actatgtcaa tccactggac atcaatattg actatgcgga
     3781 tgaagataat cctttgtctt taaaatccga ctttattttg tccctatttg aattggtggt
     3841 tggagaaaag aaattaagtg cagaagaaat ttctgttata gaccgttgtt taccaatttt
     3901 atataaaacc tactttgaaa atcctgtgcc ggaaaatatg ccaattttag aggatttata
     3961 taatcttctt caaaaacagg aagaaatagt aggaaaaaag cttgcagtag aaatggagat
     4021 ctatgtaaaa ggaagtctta atgtatttaa tcatagaacg aatgtagata caaataacag
     4081 agtggtttgc tatgacatca aagaactggg aaaacagctt aaaaagatag gaatgttagt
     4141 tgtgcaggat caagtttgga atagagttac aattaacaga gcaagtaaaa aagcaaccag
     4201 atattatgtt gatgaatttc atcttttgtt gaaagaaccg caaacagcca attattcgat
     4261 tgaaatctgg aagcgtttca gaaaatgggg tggtatgcca acaggactta ctcaaaatat
     4321 caaagacctt cttgcaagcc cggagattga aaatattttt gataatacgg attttatttt
     4381 aatgcttaat caagcaggaa cagataggga tattttagcc aagaagctca atatctccaa
     4441 gcatcagctt tcttatgtaa caaattcggg ggaaggagaa ggacttatct tttatggaaa
     4501 tacgattgtt ccttttatcg atcagtttcc aaaaaataca aaactatatt cactaatcac
     4561 aaccaaacct gaagaagtaa aaaaggcagg tgaataggat gagtgtgagc agaagtaaag
     4621 aggaattcat caaagaaaat acaaataaaa ttatttgttc ggatgcactt gaaactttaa
     4681 gaaaaattcc agacgaaagt ataagctgct gcattacatc tcccccatac tacaggctca
     4741 gaaactatca taaagaaggt cagataggaa gagaatctac agtagaagaa tacttggata
     4801 gattgttaca ggtatttcgt gaagtaagaa gagctttaaa aaaagaaggt acttgcttta
     4861 tcgtaattgg agattcttat gctgattcag gaggtggaaa ggggcaatac attgatccta
     4921 aatatccaaa ggcaagaaat ggaagtaacg ctttagctac agaaaatatc tcagggtaca
     4981 agtcaaaaga tttaatggga ataccttgga gattagcgtt acttctaaga gaggatggtt
     5041 ggtatctgcg ttctgatatt atctggcata aggaaaatgc tatgccggag gcgtgtagag
     5101 atagacctac tcgttcctat gaacatattt ttttacttac gaaatcacca aaatactatt
     5161 atgactatga tgctatggta gagccgatga aagaagtcag taaaaaaaga tatgtaagag
     5221 gaagaaaatc ggataataaa tatctgaaag aaaattccgg agcaaagttg caaaaaatca
     5281 atgaagcaag aaaatatgga gaatataagg gcgataatgt cccgcagttt cgtaataaaa
     5341 gagatatttg gactatcaat accacatctt ttagaggcaa tcattatgca acatttccac
     5401 cgaaacttgt tgagatttgt atgattgcag gttgtcctaa aaatgaaatt gtacttgatc
     5461 ctttcattgg aagtggaacg gtcggatttg tggcacttcg tcataacaga aagtacattg
     5521 gaattgaatt aaatgaggag tatgtaaatc ttgcaaagaa tagaatcagt gaggaggtga
     5581 aaaaatttaa tgaagaacaa aaacaagagg tacaaaaaga atagagaaaa actcttaaat
     5641 caagaaatac agtctttaca atctcaaact caagataatt atgaaacagg atcctcaaaa
     5701 aatcagaatg aaaccttgct gaaagacgaa acttacgata agaaacaatt tttatctgaa
     5761 aagaagttat ccaatcattt ggataataga catataaata attattcgga tagaactata
     5821 tcttcttatt gcttgtcgga tacgggaaat ataaatcaaa ataggtcttc ctttcaagct
     5881 gaaaaacata aaaaaaagat gcaaaagcag ataaataaat ttcaaaaggg agaaaaggaa
     5941 gtctacgatc ctttatcaaa agatatggat aatgatggtg taatagacag gtatgatgtg
     6001 gattttaggg atagcaaagt atcatatcga actcttacag atgatgaaaa gtatgataat
     6061 aaccaaaatg ataaaggaaa aaattataat gactatgtaa aaaatccaaa atctaagaat
     6121 aagaggtata aaaattatgt aaaagacaca ttttctaagg aaagaatgaa atcagaaaac
     6181 cagaagaaat atgtgaggag caactttgat gatgaagagt tcacaagaaa taaggatacg
     6241 aaaaataatt tatttcagga cgtaaataat aaaagaaaaa ctaccgataa aaattcatca
     6301 cgaaaaagaa aaggaaaatt tgaaaataag gaaaagaaaa tatccaagtt acagcagaaa
     6361 aagcaaagac aagagcaaaa actgaaaaat aagggaattg acgggaaaag tcaaagtgct
     6421 aaaagtgcag taatagcaac gggtatggca aagaggtatt tggaaagtgg aaaagaggac
     6481 aatgccggag taggtactgc ttataaggtt acagatcagg tcgaaaatat ttcaaggaaa
     6541 atatattatc atggaaaaaa gaaaaattta aaaaggcaaa aaaagataac aaaattaggt
     6601 aaaagcattg ataaacagga gaagaaactc ttttttcaaa agaatatgga agagatgaaa
     6661 aaaagcgtgg attaccaaaa tacctcaagg ctcagacaat tctttaagag aaggcaatat
     6721 aaaaatcaga ttcaaaagaa gtataaagat agtgtgaaaa acagaataaa aaaatccttt
     6781 atagagggca gtaaaagatt tggcgaattt gtaaagggca gagggaaaaa gataatattt
     6841 ctatcacttt tagcggtagg aatatttttt atgttatttc aggctgggag catgatgatg
     6901 aatatgggaa cgggaatggt aagtaatact gtttcaacca cctacttatc atcagaagac
     6961 accttaaaag aaatcaatca gaggttttca tctttggaac aggctttgca agaagaaatg
     7021 gacagtgtgg aggaaaatca tccgggctat gatgaatata ttatcaaagg aaaagagaaa
     7081 attggtcata atgttcatga actcttgtca tatatcacag cccgttatgg aattgtaaag
     7141 aatatttctg aagtagaaag tgaactaaaa catctgtttc aaaaaatgta tacgctgact
     7201 tataaagaag agattgaaat cagatataga actgttacat ccagctatac ggatgctgat
     7261 ggcaatgaac atactgaaag tcatgaagag ccgtatgagt ataggaaact cattgtaacc
     7321 ttagaaaaaa gagagatgga cggaattatt agagaagcat ttaagcgtta tcctaataat
     7381 ttggcacact atgaaacttt atttttgaca caaggaaata tgggagaagt atttggaaat
     7441 attgacctta taaattcaaa tggtggaatt ggtggtggta aagagtatga agcatcaagt
     7501 gaagtgcaaa agaaaatagt gaatgccgct tatattacac catctccagg agcaggttgg
     7561 tgtgccatgt gggtatcaca ggtctatcaa aatgcaggac ttggatttat tggaggaaat
     7621 gcttgtgata tgtatcgaaa ttatactttt acttctgata ggtcaaagtt aaaggttgga
     7681 atgcttgttg cagttgaaag tagcagtagt ggtagcagtt taggtgttac ctatggtcat
     7741 gtaggtattt atatcggaga tggaaaagta atggataata tcggacacat aagagtaact
     7801 accctagatg attggattgc aacattttgc aaacatcacc ctgtaggttt tggatttcca
     7861 ccatcagtac aaaaataagg agggaatatt ttgaataaaa aatatagaaa aaatatagaa
     7921 aagcaaaaag atattcagaa aaaaatagaa gaactccagt taaaacagga gatgttaaaa
     7981 gaagaacagg aagagatgga aaatattgag gttttaaagg aataccgaag tattgacatt
     8041 tctattgacg attttttaga aatgatgaga cgttataaaa aagaggaaaa acaagaaaaa
     8101 atgaagttac aggaaatgag aaatacagaa aatcataata atatggagga aaatcatgaa
     8161 aatcaaatgg aagaataaaa aaatggcgat aacattgtcc ggagtaatct ttttgatact
     8221 tgctttactt ggaacaatgc ttttcaatca ccagattgtt tttgcacaag gtagtttaat
     8281 cccgacactg attagtccca cagaagtttt agctcaaact aaagtggagg ttaagataaa
     8341 atatatattt aaggatgaga gtgtatataa ggaagaaata attgaagtag aaaccgggca
     8401 agttcttgac agtggggacc taccaatgtt agaggataat atgaaattta ttgacgaatt
     8461 tttgttctat aaagtaaagg gagacggtac agatgagatt atccgtaaag tagaaaaaat
     8521 tacagttaag gataaagaaa ttcagacaga agaggaaaag ccaaaacagg acgaaagcac
     8581 tgagacggaa gataaaaaaa cagaagataa gggaacacag acagagcttt ctaaagatga
     8641 tatttccaaa atggaaaaag aggcaaaaga gcttcaggat aaacttgata aattaaatgg
     8701 tgaaatcagg gataaagaca aactaagcga taaacagaaa gaaaaaatca aagaccttga
     8761 agctgagatt gaaagtctga aagaaaaaat gaagaaagat aagggaaata aagacttatc
     8821 agaagatatg aaaaaggaaa tagataagct gacggaaaag gtgaaagagc ttgagaaaaa
     8881 gccaactgaa acaaacaaag ctcctgtaac atcacagtct gttacaccga ttagtcctat
     8941 ttcagggatt aagacaagct caggtatttc ttctcaaaca ccacagagtt ccggtaaagg
     9001 ttcatctgat gcagtaagct ccggcaatac tacaaaagat acaggtaaaa ctgaatcaaa
     9061 ggagaaagaa aaggaagttc gctatcccaa taagctgaca ccgaaagctc ctgctaataa
     9121 cagtagtcag gattcatcaa tggacggtgc aagtagcaat gtaaatacca ataagggtgt
     9181 ggcttcagct ccgtcaaagg caagaggaac tgttacagaa aataaagata atgcgaataa
     9241 tgattatcca attcatcatg gggatagcag cgataacaaa gaagcagata agtattcagc
     9301 agatgcaaga caatttatta ctttccagac aaaatccgga aagacatttc atttaatcat
     9361 caatcacgat gagcaaagtg aaaatgtaat gcttttgact gaagtatctg aagatgatct
     9421 tctgaatatg gtagagaaga aggaaaaccc gcaagaagaa atcaaaaaaa tggaagaaac
     9481 ggtaccggaa agcgaagtaa aaaaagaaga gccgaaaaag gaagaaggta aaggtagcgg
     9541 ctcatatatt tttttaggaa tcatcgttct tgcagtagtt ggagcaggat attactttaa
     9601 aatctacaag aaaaagtagg aagatgatga ttatgatgaa gatgaggaag aatatgatga
     9661 atttgaagat gagtatgaaa aagaggacga tacagaagat ttggaagaaa cagtagaaga
     9721 acagcataac atagatgata tggcaatcga ctcttatgat gaagaagatg aggaataaag
     9781 ttataaaaag agaaatgtaa accctgatgt tgcgtttaca cttaaaaaat ggtataatgc
     9841 aagtgtaaac gcaacaaagg gggtggatgg gatgaattat gaaaataaaa ttgaaaaata
     9901 tttgaagcaa tcaggtggaa ttattacaac agcatactgt aaggaaaata atataccgac
     9961 gatatatctc agtcgactat tgaaagatgg gagattgtca aaagtaagaa aaggaattta
    10021 tataacgaaa gatggggatt acgatgagta ttatttcttt caacatcagt ataaaaaggc
    10081 gatattttct tatgaaacag cactttacct gcttggacaa acagataaaa ttccttggag
    10141 tatcgatgta accgtttata acggatataa atttaatgaa aaaccgaacg gtttcaatgt
    10201 tcattatgta aaaaaatcaa tttatgactt aggggtaacc caaaaaccta caatgtttgg
    10261 aaataaagtt aaggtatatt catatgagag gacactctgt gattttattg ctcataaaga
    10321 agaaatggat atagaggttt atgtaaaact tattcaatca tattcctctt ataaagaaag
    10381 agatatccat tccctctatg acattgcaat gaaaatggga attgaaaata aagtaagaga
    10441 ggttatggag gtggcttatg aataaagcta aattaacggc tctttgccat aaagttagta
    10501 aagaagtcgg tctttcgttt aatgctgtta tgttatatta ttttttagaa agtattttaa
    10561 aaaaattagc aggaagcaaa tatagtgaac gatttatttt taagggcggc tttttgttat
    10621 caagtgtagt tggaattgat tcaagaagta ctgtagatat agactttctt ttgagaaata
    10681 tgcaactatc agaagaaaat attgttcaaa tgctgaacga aactttaaaa ccggaagaat
    10741 tcgacgatat tttttatgaa ttgcaaaaca ttgtgccaat caaagaagaa gatcaatatg
    10801 gaggatttcg tgcaaatatc ttatgtaaaa tggaaaatat aagacagatt gtaccacttg
    10861 acattgcaac aggagatgtt attacacctc atccgataga ttataagtat gtgagttctt
    10921 ttggagaaga agaaataata atcaaggctt atccgataga aactatgctt gcagaaaaaa
    10981 tacaaactat ttatgcaaga ggatttttaa atagtagaag taaggattat tacgatcttt
    11041 atattattta taaattaaag gataaagatg taaatgtaga gatattaaga gaggcttgca
    11101 gaaaaacttt tagttataga aaaacagaat ttgacatagg taaaatcata gacttactgg
    11161 aaaaattgaa aataaatgaa gcctttttga aaagatggca agcttattca agaaaaaatc
    11221 tgtatgcgaa agatataact tttgaagaag tattggacaa cggaataaaa atggtggaaa
    11281 aaataaagaa tgaaaattag catataacgg ttttacaatg aaaagaaggc gtcaaacatt
    11341 tttttgtaag ttagttccca aacaggaaaa tggattaaaa aatagaaaat gaaatatata
    11401 aaactttaaa agacaattgg agaaatgcaa actctgattg tcttttttca tgtagaaaaa
    11461 aggaggaatt tatgcaaaca ctggtgataa gtgaaaaacc gagtgttgca ataagcatat
    11521 caaaggtgct tggagcaaca aaaaagaaag acggatataa tgagggaaat ggatataggg
    11581 taagttggtg tgttggtcat ttaattcaga tggcaaatcc ggatgcttat gatgaaaagt
    11641 atgccaagtg ggatatggct gatttaccga ttattcccaa ggactataag tatgaagtag
    11701 caaaggcaac caagaagcaa ttcaacatcc ttaaaaagct gatgaatgat aaagaaattg
    11761 atacggttat aaatgcttgc gatgcaggtc gtgagggaga gagcattttt agacttgttt
    11821 ataatcaagt gaattgtaaa aagaaaatga aacgcctttg gatttcatct atggaagata
    11881 gtgcgattaa agagggtttt gatcatctaa aagacggaaa gaaatatgac aatctctttg
    11941 aatcggcaca ggcaagagcc attgcagatt ggttagtcgg aatgaatatt agtagacttt
    12001 attcctgctt atataatcaa aattactctg tcggtagggt gcagacgcca actcttgcca
    12061 tgattgtaaa acgagatgac gagatagcaa actttaaaaa agaaaaatat tatactgtag
    12121 agctatctat ggacggtttt atactttcca cagacagaat tgatgataag gtagcagcag
    12181 agcagctaat caatttagtt ggtgataaga ttgaaattac cgatgtcatt caaaatgaaa
    12241 agattacaaa gccggattta ccttttgacc tgacaacact tcaaagagag tgcaataaat
    12301 attttggata ctcagctaag cagactcttg attatgctca aagtctgtat gagaagaaac
    12361 ttattaccta tccaagaaca gacagtagat gccttactga agatatgatt acaagtatga
    12421 taaataacat attgggacaa aatgactttg atacagggcg tattaaggtc atttttaatt
    12481 caagcaaggt aacggatcat catgctatta taccgacagt aagttcaatg agtgaagatt
    12541 tattgagtat tccggagagt gaagcaaaag tgtatggact tatttttaat aagttacacg
    12601 caagtgtggg ctatccttta atcgagaata caacaaagat tgtagtgact tttgacggct
    12661 ttaaatttac aagttccgga aaagtaatta aggatgaggg gtttactaag tatttaaagg
    12721 aatataagac gaaaaagaat gaagatatag aacttccaaa tgtaaatata ggtgatagtc
    12781 ttaaaatcaa ggataaagaa atcaaagaaa aatatacgca acctccaaaa cattttacgg
    12841 aaaacacctt attaaaaagc atggaaacag caggaaatga cgctttaaaa aaaggtattg
    12901 aggttgaaag aaagggtatt ggcacacccg caactcgtgc agggattata gaaaatctaa
    12961 tttacaaagg ctttattcaa agagataaga aaaatcttgt agctacacat aaaggaatta
    13021 gtcttataac aattgttgca gacaacttta aatctgctga aacaactgca aagtgggaaa
    13081 tggagttgtc tgatatttct caagggaaat cttcaaagga agaattttta agaagagtag
    13141 aagctgagat aagaaatgaa ttatcccgtt ataaaaagga ttagtctatg tttgatactc
    13201 taataaaatt tagtaaagac agagaaaaat tggattttta tgccacagat aaaagggcaa
    13261 ttcatgaact tttaaaaaga gagcagtttc tatctcctat ttatgagccg gcttgtggaa
    13321 tggggcatat cggaaaagtt ctggaagaat acggttataa ggtaaaagct acagatattt
    13381 gttatagggg atatggagaa gaaagagaag ttgatttttt tacagtaaca gaaaatatat
    13441 tggatatagt aaccaatcca ccatattttt gtgcaagtga gtttttaagg cacgctcttg
    13501 aaatatcagg acctaaagta aagatagcaa tgctatttcg gttggctttt ttggaaggtc
    13561 aatcaagata tgaattattt aggaaatatc ctccaaagag agtatatgta ttttccaaaa
    13621 ggcttaattg tgcaaaaaac ggagaatttg agaaatacaa aagcagtgct attgcctttg
    13681 cctggtttat atgggaggtg ggatacaaag gtattacgga gttaaggtgg attagataaa
    13741 aggatggaat aaaacaactg aaaaaacgaa ggaggatagt atggataaga atgaagtatt
    13801 acaatcacag gaaaatcaga caaaggaagt tatgcaggag attaaagagg aatataccaa
    13861 aacagctgac tttttagaag aacatataaa tcagcagctt gtgattgcta aggaaatgaa
    13921 agaagagatg caaaataagg actttgatgt aaatatcaaa gaattgaaag cactcaaaga
    13981 agaaatcacc ggattaaaag ctgaaattaa acgattaaac gaaatggaaa atataacttt
    14041 tggttcattg attataagag atatcaaatc tgtaggaaat acccttatca atttacagga
    14101 aaaagcggta ggaagtatta aacatctgta tgataatatg aaacatcagc tttcctataa
    14161 ccttaccaaa gcacaggaaa aatttgtaca gatgaaaata ggaattgtaa aaggattggt
    14221 aaattccatg caggatttta tcaaggatca acaaaagaaa ctggatagtt gcttagcaaa
    14281 acttgataat ctatctaaag aaattcaaaa agatgaagaa aaactggaaa aaggcaatct
    14341 gaataaagag aaaaccctga taaaaaaaag ggaacaaagc atagaggaaa aagaaagtca
    14401 aaaggaaaag atggagaaaa aaccgtctgt gctaaaaaaa ttaaaggaaa atcagcaaaa
    14461 aatcaagcag gaagaaaaga ataaagatat aaaggcactt aaaaaagata agggaatgga
    14521 actataaaaa agaggtggta gttatgaatg acctcataaa aaactatgaa aatattcctg
    14581 atgagatgaa aaaagagaag cgttggtgcc tatataaaat cattcaaaga gacgggaaga
    14641 acacgaaact tccactaatg ccaaataaag agccggcaaa atcaaatgat aaagctacat
    14701 ggaatagcta tgaggattgt atcatggcat taaaacataa tgttggcgaa gggcttggct
    14761 ttttcttagg agatggatac attggaatag atattgataa agtaagtgat gacattatgg
    14821 agtacaatac gaatcatcat gtaagctcta tgacggctga ttttttaaga gaagtttcca
    14881 cctatgctga gatttctcca tcgaaaacag gactacattt tattggaaaa ggagaggtgc
    14941 cgggagaaag aaaaagatat aaaaatcttg aaatttatga taaggatagg ttttttacag
    15001 ttaccggtaa tgttataaag gatagagata ggagcaaaat agaaagtatt gacagtgagc
    15061 taaagccctt atatgaaaaa tatatgccaa agacaaataa aattagtgct gaaaataaaa
    15121 gaagtccaac ggttacttct tacaatgggg atcaggacat attagaaaag ttatttgaca
    15181 ggggatattt ttcatatgca ggagaagatt taagacaaat ttactatggt aattatgaac
    15241 gctattttaa cagccaatcg gaggctgatt tttttatgct acaaaggctg ctttactata
    15301 caggaaatgt agaaatggca atatcattta tggaaagtag cggactgaaa agagaaaaat
    15361 ggtataaaag acgaggcaat accgattata tccactatat tgcagataag gcgataagct
    15421 ctatcaatca attttatgat tgggaaaaag tatatacatc aaaggaaaaa atagaagaaa
    15481 aaagatatga aaataagaag aaaaaggagg gagatacagt gccaagatat gaatttgatg
    15541 aagtcaaaca gattcttgat tttgcaaaag aagaatttaa agaaaatata gacaggtatg
    15601 aaacttatct caaagtgatg ggaaataact ataaatatcc gtactttaac cagcttagca
    15661 tatatacggt aaatgaaaat gcaactgctt gtgcagaata tgactattgg aaaagtatag
    15721 gaagaaatgt aaatagagga gaaaaaggaa tacctgtttt agacattgaa agagagaaga
    15781 taaagtatat ctttgatgca agtcagacag taagtttaaa tcacaacatt tctgaagtaa
    15841 agttatggga atatagcaat aataagcatg tagctgcctt agatactctt atcgatgttt
    15901 tcaaagaaaa aaacagtaac cttatatttt ctactgaaga taagataaat acaatcgttt
    15961 cactatatac aaagcaatta ctaaataagg tacttaattc tttaagtgat gaaactttaa
    16021 aggaaaataa gaaagtacaa attcttcatt ttttggaaga atctgcaaaa gtatcggtat
    16081 atgagagaat gggagttgca ttttccggtg atatagaaaa attagagatg ctttcaaatg
    16141 tttcaagtat gcaggatatt gacagattac ttttctttac ttcaaacaat gtaaaaagaa
    16201 tacttatgga tataagtaga gaaatttcaa aagtggaaga aagagaaaaa atttcagaaa
    16261 ttcaaaaaag ggagcagaca aatagtattg cggagcgtta tactaatgtt acagatgaaa
    16321 ttaacggaaa taccgaaatt atagaaaatg aaaaagaaag aaatgaagga ggtttggaag
    16381 atgaaagaaa ccgtagtatt ggcgaagaag gagtacatcc tagaaaacga gatttataca
    16441 ccgatcgtaa aagagagtcc attcgagaga cagggaggga cttacagatt ggagaaaatg
    16501 gaggatggag cggaagtatt agttccgaat atgaaaatgc cggagaaaat aaacgcaagc
    16561 aaactgaacc gatttggcaa ggagagactg aaatatctca aagaggagaa acaagaggaa
    16621 tatcagatta tgctgatgga agaaacttta atggatcatt tgatagatat tcaggaacaa
    16681 gtggaggatt tcctgaatat agaagagccg aggatgaaag aagcttggaa aatgaccaca
    16741 gaaatgcagg atcaggactt tctgaaatac acaggactga agaagaactt ggatatgaca
    16801 ctaacaaaaa tggctatgga acagatcatt tgggtataga tgagtatcgt aaagaaaata
    16861 tacagaagat agaacaaaat catgtagaaa atgaggaaaa agaagtcgag aggacttctt
    16921 tttcttttgc tcaaaatgta ggagttcaag gaagatttga attaccaatg cagcaagaag
    16981 agattggtgc tgttttaatt catggaggaa atgaggataa tttacattta aaggttttag
    17041 ccgaatattc taaagaaaaa agcatggaag aattagctga ttttcttcaa aaaacttttc
    17101 aaggaggaaa tggatatgaa ctaaatggaa ataaggtttg tgcttggtat gaaatggacg
    17161 ggatacattt atccaatgat gtttcctcaa gagaaaatcc tatgcagatt ttaccatgga
    17221 aagatgcagc aatacgcata ggagaattga ttgattatgg aaaatacagt acaaatgtgg
    17281 aggtagcaga agccttttct tttgaaagag cagaactttc tgaaaagctg tggtttttaa
    17341 aaggagatct aagtgatgag gtaaaaaatc agtttttgcc aattctaaat gaaaaacaaa
    17401 gaaacggata tcctgaaaaa acagagtatc ttacaaaaaa attggaagat aaagagttta
    17461 gagtgaactt aaaagaggag tatatagagt tttttaaggc gtataaggag aactcgaatg
    17521 ttttaagatt tcataatcat gatttagatg atatatcaaa acgattagat gatttggaac
    17581 tgccaagaaa agaatttacc tcaacactta tagaattacc agcaatacag ggatttatca
    17641 cagaagatga aattgataga tatttaagca gcggtagcaa tgtatccggc ggaaaagaaa
    17701 gaatatataa cttttttagg gaagcccgta ctaccgaaga acgagcaaat tttttaaaag
    17761 acgagtacgg aacaggagga cagactcatg ctttatcaag ggcaagagga agtagtgagt
    17821 ggcacgatgc taaggggata aaacttgaaa aagaaaattg taaggatatt attttgaaat
    17881 ggaatcaggt tgtaaaaaaa atagataacc ttattgaaaa tggaaaatat attcaagaag
    17941 atgtatatac agagcaagaa agcataaaaa ctgaggaaga atattttgat gaagatacct
    18001 atacggaaca aaactctaaa gaaaatgaac aagattggca aagagaacag gaaattttgc
    18061 tgattcaaga tgaaagagaa gtatcttatg aagaggcgga ggaaatatat gaaaggcaag
    18121 cagaaataga acataatgcc tttgcaaccg gtgtagagaa taacatatcg tcaactcaaa
    18181 gtaacaagga ttattggatt gtagaattta atgaaggctc aaatctgata gaaaaaaatt
    18241 atgccggaga agttgttacg aaaaaattgc ttgatgaaat caaggtgctt gacgaaaaaa
    18301 ttagagttca taataagact gtcggtgaag atgaatacgg agaaatgaca gatgaatggg
    18361 taggttattc taaattctat tttgaccata ttgtagacgg gaaagtagaa gaacacttca
    18421 gaatggatat cggggatgga aatgaggtaa accaaagaga ttttcaatat ctttatgagc
    18481 agattgaacc ggaaaaagaa aataaagaat acgggatgga tagtatagat agtgtcataa
    18541 aagatatttt agaaaaagaa tctatgactg tggtatcaag caaagatgat tatataaagt
    18601 tatttccata ttttagaaac tttgtatata ccgatggtct aaggcttgat gaatataatc
    18661 cgtttgaaga tgatgaaaat atttcggatt taattcgact gacttttttc caaaataatg
    18721 atggagaata tagggtagtc tataacaatg cggacagttt actgtattca agcaatgttg
    18781 actatttttt ggagaaaata gaggctgaaa aggtaaggtt agaagataat atagctgaga
    18841 taccgaatga agataaaatt gccgttaagg ttgggaatta ctatgctgtt gtagaaaaag
    18901 aaagagtaaa ggatatatcc ttagaagaaa caggagttcg tgtttatccg aaagaaaata
    18961 actttgaggg aaaaatttac ccattgtatc gtggcagcac ctttgaagaa agtgcaaaaa
    19021 tagataaact tttcgatgag attgcaatag gcatgaaaga ggtcaatttg accgatttaa
    19081 atgatgtttt ttatcttgaa aatcaaggac tttatgaaat ttcatcggat agggtaacgg
    19141 aagaaaaagc cggatacgat tttgaagtgg caagttttaa tgaacagttt cctgattact
    19201 ataatgacat ttatgtatat aacagaaatt taaaaataga tggtgctaat caaaacattg
    19261 catatatcaa tagagaaaat gaaatacatt ttaatgtaaa tctaccggaa gaagaaaaag
    19321 caaaggtgct tgaaattaga gataagaaag aagtcttatc aactcttatt tttaaagatg
    19381 taaaggaggt cggcgaatat cagtttcatc cacaaagcga agaatttatc ttaaatgaat
    19441 tgagtatatc tgaagaaaaa ttaaaagcac cggaacatat aacagataag attgataaga
    19501 aagaaggcta tgaggctgaa cttgttttgg atatgaaaaa caaggagtta aggcagcatt
    19561 taagatataa cggatatatg ttaagtagca atgtggcggt ttcctatgat agttataaag
    19621 caatacttaa aaatctttct tatctgcttg atgataatca tagaaatatt atgcttaccg
    19681 gctatgtcaa cgaacagatt gaaaaggata aagcaaagga agaaagaaaa gaacctgtat
    19741 atcaagaggg aatgaatgta aggtatcaag gcaaagaata tatcatttca gaaattcaag
    19801 actataaaac atataaaaca ataaagctag atgattcaga aggatattta aacggcttta
    19861 taacgggcag tgaaattatt ccttttagaa atgaaagaga acttgatttg gaaatcatat
    19921 ctacaacaga gaagttacaa gaacaaagta taaatggtga agatcttatt ctgttagata
    19981 ttgaagaata taacaaaaaa ggactttccg ttatctttca aaataaagag tatgaaatta
    20041 caggaaataa ttttaatcct gtaggaatga gcaggttaca acttgtctcg aatacagaaa
    20101 aactgatgac agaaatttca tatacacctc aaagaccggt cgcaaatctt tatgcaaaaa
    20161 aagatctcct tgaaaggttt aatttaaatg agaaaaatag tgaaaaaagt attgaagcaa
    20221 agcaaatgtc tttaacagat atatttgagg aacaggatac aacaaaggga aaagaagaaa
    20281 tttcaagtga gaaagaacgt gtacctgtca atataggggc aaaggtaatc tatcagggag
    20341 aagaatatac agtaagtgcc tttgagtata ataatatttt agagaaaaat gatatatggc
    20401 taaatcctgt atcaaaaaat aatcatcaaa ttccgattgt aagtttttct gacagagaag
    20461 agctaaatga aaagctcatt gttatagata ccaatcttaa cttaggagaa gacaagtcgg
    20521 aactgttaca tcatagttta gatgtaataa atgataaagg ttctgtgatt gccaatcagt
    20581 ttattgtaaa agtcgataat caaaacaggg aacttacagt atatagtgaa caaaatccta
    20641 atagtcatag agaatttgaa ctttcttttg attatctaaa cgggcttggg caaattgacg
    20701 gagatggaaa taatctaaaa cttacaaagc ataaaaaaga aaccattgat aaaaaattga
    20761 aaagttatca ttcttggaaa gaagatgggg aaaaaagagg aattccggga atagcaggtt
    20821 cttctattac ttcacctatt actgatgaaa tgttttggca gatgaaagaa tatgaagaaa
    20881 aattaaaaga ggaggaaaga tacgcccctg atgataagta tttgggaggt attcctccaa
    20941 tcaattacaa aatcacaaaa gaagatgaaa tcttgccgcc gtccgaaagg cttaaaaata
    21001 acatagaagc catcaaggta ttaaaagaaa ttgaggaaag acatagtcat gcaacaaagg
    21061 aagaacagga tattttgagt agatatgtcg gctggggtgg actttctgat gtctttgatg
    21121 aagaaaaggg aggacaatgg aaagatgcaa gagaattctt aaaagaaaat ctatcaccgt
    21181 ctgagtacga tgcagcaagg gaaagtaccc ttacagcctt ttatacaccg aagattgtaa
    21241 tagacagtat ctatcaagcc gtattaaata tgggatttga aagtgggaat atcttggaac
    21301 caagtatggg aactggcaga tttataggca atcttccaga cagcatgaaa ggcagtaaat
    21361 tttatggtgt agaacttgac agtataagtg gtaggatagc aagtaggcta tatcctaatg
    21421 ctaaaataca gatcaaaggt tttgaagaaa cgactttttc aaataatctg tttgatgtag
    21481 cggtgggaaa tgtaccgttt ggagaatata agatagttga tcgtgagtat gagaaaaaca
    21541 attttcttat tcacgatttt ttctttgcca aaaccttgga taaagtacgt tccggtggag
    21601 tagtagcctt tataagttca agtggaacta tggataaaaa gagtgaagat atcagaagat
    21661 atatttcaga aagagcagag tttttaggag caattagact acctaataat acttttaaag
    21721 gcgaggcggg tacggaagta acaagtgata ttatttttct taaaaagaga gatcgactgg
    21781 taaaacttga tgaagaatgg gtaaaacttg gcactgacga aagaggactg acatataaca
    21841 aatactttgt agataaccct gatatggtac ttggaaatat ggaagaaata tcaagcagat
    21901 ttggaacaag tcttgcctgt gttgcagatg aaaatagtac tctgaaagaa cagctggata
    21961 ccgccattaa aaacattaaa ggaagttatg agaagataga attaaataat gaatttgaag
    22021 tggaaaccat tccggctgat gacagtgtga aaaattattc ttatgcagta attgatgata
    22081 aggtatattt tagagaaaat tccgttatgc aaaaattgaa tttaaataaa aatgatgagg
    22141 aaaaagtaag ggcatatctt ggaatagaaa aagcattaag acaggtaatt gcttatcaaa
    22201 aagaagatta ttccgatacg gaaattaagg agaagcaagg ggagttaaat cgtatttatg
    22261 atgagttttc caagaaatac ggaattttaa acagtaaggc gaataaaaaa ctgtttcgtg
    22321 aagacgctaa ttattcttta ctgtccactt tggaaaagct ggataaagaa ggaaacttta
    22381 tagaaaaatc cgatatcttt acaaaaagaa caataaaaaa agcagtagcc atagagcata
    22441 ccgacaatct gacagaagca cttatcctat ctatttctca aaaagggaaa gtcaatttcg
    22501 agtatatgga aaagctcact gaaaaaacaa gaggagaaat cattgaagga ttaaagggag
    22561 aaatattctt aaatttagat ggatttgatc caagtgatac gactcctttt tcttcagcca
    22621 tagacttggg agatttttca agatcttacg taactgctga tgaatattta tctggaaata
    22681 tcagagataa aatagaagta atagattcgt atataaagaa tgtagaacat gaatttgaac
    22741 aaaatgaaca gcttgaaaat attgatgcag atgtactgaa acagggtagt gagactttaa
    22801 aaaaagaact gtccagttta aattaccaaa gacaaaagct gctagaagta atgccaaagg
    22861 agcttgaggc aagtgaaata accgttagaa tgggagcaac ttggatacct gagaaagatt
    22921 ataagagctt tatgttccat cttctaaaaa catcggcatc taatagatgg aatattgata
    22981 ttaaatatac caattttaca ggggagtaca gagttgaagg taaaagtata gataaaggaa
    23041 acgaccttgc caatttcaca tacggaacaa gcagagtaag tgcatataaa ctgattgaag
    23101 atacattaaa ccttagagat accaatgtat atgatcaagt cattgatgaa aacggaaaga
    23161 aaagttctgt actaaatcaa aaagaaacga tgcttgcaag aagtaaacag gaaattatca
    23221 aagaagagtt taaaaattgg attttcgatg atatagacag aagaacaagg cttgtaaaag
    23281 aatacaatga gaaattcaat tcgataaggc ttagagaata tgatggaagt aatttaactt
    23341 ttgacggaat gaatcctgaa atagagctta gacctcatca aagagatgcg attgctagag
    23401 gacttttcgg tggaaacacc ctacttgcac atgaagttgg agctggaaag acttttgaga
    23461 tgataggaat tgctatggag tctaaaaggc ttggaatgag taacaagtca atgtttgtag
    23521 ttccaaacca tattgtagaa cagtttggta gagagtttaa tgaactgtat ccggcagcaa
    23581 atattctttg tgcaacagaa aaagacttta caccagataa aagaaaaaga ttttgctcaa
    23641 ggattgcaac cggtgattat gatgcggtaa ttatagggca ttcgcagttt gaaaagattc
    23701 caatttcaaa gcagcgacag gagtatgaac ttcaaagtca gattgatgaa attatagatt
    23761 ttatcgaaga atataaaagg aatagagatc agaaattcac cgttaagcag cttgaaaaaa
    23821 cgaaaaaagg actggaggca aaactaaaga aattaaatga tgattataga aaagatgatg
    23881 tcgtaacctt tgaagaattg gggatagaca agctatttgt agacgaagtt catgctttta
    23941 aaaatttgta cgtttttaca aaaatgcgta atgtagcagg aattacaacc acagattctc
    24001 aaaaatcaag tgatatgctg atgaagtgca gatatatgga tgaaattacc ggtaataagg
    24061 gtattgtatt tgcgacagga acccctgtga gcaattctat ggcagagctt tataccatgc
    24121 agcgttatct ccaatatgac gaacttaaaa aaatgcactt gcaacacttt gattcttggg
    24181 catctacttt tggagaaact gttacagcaa ttgaacttaa tcctgaaggg aacggatatc
    24241 gaagcaagac aagatttgca aaattttata accttccgga actgatgaat atggtcaagc
    24301 agtttatgga tataaagact gctgatgtat taaatcttcc cgttccaaat gctcattatg
    24361 aaacgataaa aaccaaaccg acagaagaac aaaaacaaat ccttgaaact ttttctgaga
    24421 gagctgataa ggttagagga aaacaggtgg attcctctgt cgataatatg cttctgatta
    24481 ctaatgacgg aaagaaaatg gcacttgacc aaaggttaat taatccatta cttcctgatg
    24541 atccgaacag taaagtaaat acctgtgtaa ataatatatt cagtatttgg gataaatata
    24601 gggatgagaa gtccacacaa ttagtttttt gtgatatgtc aacaccatca agtgaattta
    24661 atatttatga tgatataaag gagaagctga caaaaatggg gattcctaaa aatgaaacag
    24721 agtttattca taacgcaaag aacaacaaag aaaaagataa gattttcgat aaggtacgaa
    24781 agggtgaaat tcgtgtgctt ctcggttcaa cgcagaaaat gggagcaggg acaaatgctc
    24841 aaaataaatt gattgctacc catgatctcg atgtaccctg gaggcctgcg gatttggagc
    24901 agagaaaagg aagaattgta aggcaaggta atgaaaatga tgatgttcat atctttcgtt
    24961 atattacgga aaataccttt gatgcgtatc ttttccaaac acttgaaacc aagcaaactt
    25021 atatatctca aataatgaat tcaaagacac ctgtaagagt agcggaggat attgatgaag
    25081 ctacattaaa ttatgcggag attaaagcac ttgcaacagg aaatccgctt attcgtgaaa
    25141 aaatggacct tgatgttgag gtaagtaaac ttaaaatgct ggagtccaat tttaaatcca
    25201 acctatataa aatggaagat aaggttgtaa aagtatatcc aaaagaaatt aaaagtctaa
    25261 aagaaaaaat agaaaatttg aaaaaggata tagaaaaagt ggaaccgtat agggaggaaa
    25321 aactagaaaa atatgatcag actactttag aaaatatggg tgaaaatgaa aaacaagtgg
    25381 ggataaaagc agataaagaa gcaatatcaa aattcacatc tttaacttta aatgggaaaa
    25441 aatataccga taaaaagcaa gccggagagt tcttaataaa caagataaaa ggaataaaaa
    25501 aattagatga ttttcgttct gaggaagtaa aaatcggaga atatagaaat ttcgatttgt
    25561 tcgcatatta tgacaggttc tccaatcagt ataaattcaa tctgaaggga gaagaaaatc
    25621 attatgggga gtttggaacg gatgaaatcg gaaatatcac ccgaatggat aatgtacttg
    25681 ataggatgcc tgagagattg gagcagacac ttggaaaact taaagatacc gagaatcaac
    25741 ttgaaacggc gaagcttgaa ataaaaaaga aatttccaca ggcagagctt ttaaaagaaa
    25801 agacgttaag acttgctgag gtaaataatt tgcttgatat gggacaaaaa ggagatttaa
    25861 aagaggagaa aaatccactt ttggaagaag tgaaggaaga actgattcat tttctaaata
    25921 aagaatatga tgaagcacac agtatagaag atttcgatac aatgtttcct gacttgacag
    25981 atataggttt ggcatatacg actacaccgg atgaaaagca tgagatacag acaagtcttg
    26041 atttaatcaa ttacaagatg aacacttatg tagacaatac tttaattgac agttttcagt
    26101 atacttacga tccacttaat gcaagtgata cgaaggaact tatacaaatc aaaacgaaca
    26161 taggtttttg ggattttaat gagctggtat atgtggatga agaaaagtta aaagcatcac
    26221 ttggacttga aattgatgac gatggtaatt tctatgatcc gctttcaaag gatatggatt
    26281 tagatggagt aatggacagg tatgatgcag actttagaga tagtaaagta caaagttttg
    26341 gagatttgga taaaaaagaa aaagcatccg taatggatag gcttggatac ttcaaagaaa
    26401 agataaagaa aggaggccta caaaatgaaa atattgatag aaagatagag tgtaaggagg
    26461 aggttagata gttggaatat cacaaaaata ttagagcaac ggatagagaa atgcagaaac
    26521 tttttgaaaa tgaggagtat aactattccg taagatattt tgaaaaaata gaagaaaact
    26581 tatttaaaac gataattcgc acaccggaga atatagagtt tccaaaatcc aaaaccttgt
    26641 ctataaacac gataaaaaaa ctcttagaaa cagatgtaaa tattaactct atgtatatca
    26701 gagatgaatt cactaaaatg aaaaataagg tatacgaatt taatcaaaaa aaatatccgg
    26761 gttatgagga tatggatata aaactaacaa tatctactat taagggtatc gaggatttcg
    26821 atacccttaa tgatttttat gatagtttga aaaggaaggg atatttagaa gcgataaaag
    26881 aaagtattaa aaatattatt gataaagaat tagaagaaaa catacaagta aaagtacagg
    26941 aggtaaaaaa tatgaaatta gaaaaaggcg atattgtaaa aacagcatta agtgaaaaca
    27001 caacagtttt ggatgtgaaa gataatcagg cggtactgtt ttcaggtact cagtttgtac
    27061 ttgcaacagg gattaaagaa aacaaggaaa gcggaaaatt tgaatgggat aatgggcgat
    27121 atgcaaatga tttaaaaagc atttccgata tacaaaacaa taattttgaa acgatgaaag
    27181 agaccttatc ttttttagca gagtataatc atagcgattt tgtcaaagga attctgtctc
    27241 ttgaaacagg aatagaaaat gaggatactc ttgatgctgc ttatgataat tatatgaatg
    27301 ataaaattat gggtttggtt gatgaaaaat tttatcatta tatagatgaa aatgagattg
    27361 aagcacctga tttagaaagc gaaatacagg ataagaatag tgttttatcc gatgaggaaa
    27421 atgtaaagga ggacaataat actacgagtg agaagtcaaa tgaaaataag gaaaaagcaa
    27481 atactgtaaa tatcaatggc aatattgctt cagatataga cattaaaaat ttgacatcga
    27541 aagatggtag agattttact gttgcaagtt ttgcagttgc tgaaaatgac aaggagggaa
    27601 atgtaaaata taccaactgt ttagcctata acgataaggt aagtagtgta gaaaatttga
    27661 aaaaaggaga ttttgttcat gtattcggaa aagaaaaaat cagtcaggga aaggacggaa
    27721 aggaatatac atctcttaaa gtttattctg caaagctgtt aaaagccaaa gaacagagca
    27781 aaacaaatca aaatgcaaag gatgtaaaga aaccgtcagc acttggcaag ttaaaagagt
    27841 ataaggaaaa ggcaggcgaa aaatcaaagg aacaggtcag tgtcaaaaaa gataaaaata
    27901 tagagagata aaattataaa aatagtgggt aaatagctga tagggctgtt tatccactat
    27961 ttttctttgt ttttttatta gaaatggaaa aataaaggtt tgataaacta taacaggagc
    28021 gttatattat aagaaaaaga agattatttt gatagagagg tgaatgatat gattggattg
    28081 gttattcttt ttatagcctt aattatacta tatttgggag tcattctatt tgcaggagca
    28141 acatttgtaa aaattagcct gtttgcactg gataaacttg tggtatttat agcaagctgg
    28201 tactataccc accactactt ttcagtgaaa ttctcatccg gatatgctat atatttttgg
    28261 gatattctgg cagcaatatt ggtagtaata atatattcta ttctatttca gttcatacac
    28321 aaaaaattta gagtgttagg gaaaatctta aatttagcta tttcattttt tagctctatg
    28381 attgtatatt gcctcctggt gaatggattt attacaactg aaaaatccta ttttctgcca
    28441 cttttaaaca acagctttat gaatcaagtg gtcaattata ttataatcgc tattatttct
    28501 ttggttgtgt ggaaaagaag agaggactat cttgtagaaa cacacgacaa ataagaaaat
    28561 attattgtga aatattgtag aaaatatact tttatcaatt tgagagcaag taaggagatt
    28621 attcttacct gaaatatggg tagggataat ctccttcttt tttttatttt tcaaggctgt
    28681 tatcaaggta taaatctgta tttttctttg cttgttgcag cttgcgaagc atagagtttt
    28741 gagaggaata ttctcccata agtgtagttt tttcttgttc taaaagcata tatttatcag
    28801 ataaattttt aatgctcaat gtttgaagct ttgaattttt aagacttttc atagctgttt
    28861 cataggcgat gatctgtgat ttatattctt cataaaaggc tttgttttcc ttatctttta
    28921 tatacatatc ataggttagt tgattttcag aaatcgtatt tttattttct attacagaat
    28981 aaatggactt catttctttt tctatttgct ttatatgatc caataattgt tgtctatctg
    29041 atgccacttt ctttaatttt aaatctaatt cctcgtagga gttaatacct gattttctca
    29101 tttcatttaa ggcagatgcc atagttttca tattatgttt acctgcccat acttcatatc
    29161 ccttagatga ttttaccttt tcattgtttt tcatatctac aatagtatcc ggtttcttgt
    29221 aggagcgttt ttcataatga tattcctgat taacataaat attttgctta tttgaatctt
    29281 cgattcgttc cttgattctc tcttttgtat aatcttcccc taaagtagat gctttcgctc
    29341 tggtaaatct tcccttatct cttttatctt tatgtcggaa ggaaaggtat tttcctattt
    29401 tgatttcata accgaaatcc tccattgtct ttagaaattc ctcgtaagtt ttggatttta
    29461 aaacagcttt atcaatagta agttgtagtt tattcttcca agagtttcct ttcttaaatt
    29521 cggtatattc catataggtt ttaccatttg tagagtatct gtttttaaat tttttgtagt
    29581 tttcatcaat aactgacaag ccattttctc tacataaatc atcactgacc gttcggattt
    29641 gatgataact tctcttatta ctttgatatg cctttcctgt ttcaaagctg acattgttaa
    29701 acagaatatg attgtgtaga tgccccttgt cgatatgtgt tgtaaggaca tattcatact
    29761 ttcccctcaa gactctctca catagatcca gtccgatttg gtgtgcctgc tcaggtgtag
    29821 tttctcctgg agcgaaggct tgaattagat gccttgccaa gatttttgct ttggaattac
    29881 attctttttt tgtatgttca aattcaagat gggctgtttt gggattgcag ccaaaagagg
    29941 agataaggat tttttcatcg gttttatctt cattcataat atagtctaat gctagataaa
    30001 gtgttttttc tatcggatga atttttgtaa ctgccattag atttcctccg taccacttgt
    30061 tccaaaattc cctaattcat atagcttttt acgaagaaag tagatgtctt ttccttgttt
    30121 ttccaagagc tttttcaaat cattgatgtc atctttgtaa attacagcag ttgaatttac
    30181 cctttttgca atctgattga tgctacctgt aatccttccg atatttgtag acatctcctt
    30241 aaacactttc atatccagta caaaaatatc tttttcaagg atgcacttca taataaactg
    30301 tcttaaactt ttacaaccgg acagttcata ttttttattc aaaatttcaa gttcatcatc
    30361 agaaagcata aggtatattc cattatttct tgttctgttt gccatagtat aacctccaat
    30421 tcatagatgt attaaaagtt tacaaaagaa aaaacctgta aaatcaagta caaacttgat
    30481 atacaggttt catttttata tttctttgtc aagaaatctc ctgttaagag ataaaattct
    30541 tatttaaatt tcaagagtat tatatcattt gttggagaaa aattcaatga aagagaggta
    30601 atatacggat aaatttatgg aaaaatttaa gataataatt acaaataaga ttgatttcac
    30661 aggggtttgg ggattccccc aacaagctaa aattgaggaa aatagtccga tgcaaaagca
    30721 agggctatgt caattttttt cgtaagtgca tatgcattta ctgtgcttgc tcaaaaagaa
    30781 aaaaacatat ataatgaatt agcgaatata tggtatgaag tattcggaat ttttatgttt
    30841 atgattggtt atgataaaat ttggtataaa aaaaaagtag tataacaata ataagaatgt
    30901 tgatttaaag aataattaga agggataagt tagatgagtt tatgaataaa atatatcata
    30961 aggaatatgt agaacaaaat tatttggaaa atatttatac tctatactta gagcgagacg
    31021 aagtaagaaa tatagatata gtagataaac ttggggttgc aagagcaact gtaacacata
    31081 tgttgagaaa tcttgaaaaa aagggttaca ttaaatatgg tgatgataaa attgttagat
    31141 ttacatcaaa gggaaggact ttagcagtcg agttatatga aaaacatatc tatttgacac
    31201 aagtttttaa acatattggt gtagatgaga agatagctga aatagaagcc tgtcaaattg
    31261 aacacataat atcaaaggat actttcaata aaattaaaaa atattttgaa gacaagatat
    31321 aagagaaaga acatgcaatt aatttttaaa attgtatgtt ctttattttt tgataattat
    31381 aaaaggtata taacttagtt tcttcaagcc ttttagatat agaaaatata actataaaac
    31441 agtgtaaatg tattgacttt ttatgttaga aggattaaac tattattgtt agatgtatct
    31501 aacaataata gttctagtag tatattaata atcagatgga aggtgttttg atgggaatgt
    31561 ggttcgaata cgttaataaa gaaatggaaa acacgaaagc tagtttattt gtgtttccat
    31621 ttgcaggtgg tggagtatca tcattcagaa gatggggtaa tcaatttaaa gatataaatc
    31681 tcttcgttgc acagtatcca gggagagaaa acaggttttc tgaaaaagca attagcaaca
    31741 tagaagaact tgtaaaagga ttgtttgaag acttaaaaat gacttttgat tttaactcac
    31801 cttattattt tttcgggcat agtatgggaa ctaagattgc ttatgaattg gctctgaaaa
    31861 ttaaagaaaa tgggttacca aatccgaatg gaattatcat atcagctggg cgagcccctt
    31921 gctataagga accgaatccg atttatcatt tagatgatga aggatttatt gaagggttaa
    31981 gaagatatga tggtactcca aatgagatat tagacaataa agatttgatt gggatttttt
    32041 taccaacact aagagccgat tttattatcg atgaggacta ccaggataca aaaggggaaa
    32101 aattgaatag caagatttta ggtctgatgg gtgatattga tgaagaaatg gaacttgaag
    32161 aacttttaaa atggcaagat tatacgacga aagaattctc ttacagatat attaatggca
    32221 agcatatgtt tgtaaataca tctcctgaaa gtgtgataaa agcaattgaa gaatttgttt
    32281 attccaatga aaatatatag aatagaaatt tcagataaaa aagaactacg aagtttaatt
    32341 gatataagta ggttactaat tttttttgat atggtgttag ttacatctaa cacaagtgaa
    32401 tttatgataa aagatttgaa aaattttttg aaagaagaag aaattgaaaa acttgatgca
    32461 tataagtcgg aagttgcgaa aataaatttt gcagtttcaa gaagtctttt aaacaaagtc
    32521 tttgaaatga tattaggtgt tccaattgaa aatatagttt cttttagaga taagcataat
    32581 aaaccatata ttgaaaataa aagtggagtg aaatttaata tttcacatac ggatggattt
    32641 gtagtaattg gtttttcaaa gaaagagctt ggaatagaca ttgaaaaagt gaatgatggc
    32701 tttgcgtttg aagatatact tgaaaattgc tttacatcca gagagattaa gaatataggc
    32761 agtaatatac caatgtttta tagatattgg acagcaaaag aagcctacct aaaatatgaa
    32821 ggatatggtc ttataagaaa tccgaaagaa atagaagtta tttatatcga caatcagaga
    32881 ataaaaattg aagataaggt aaaaaggagt aataaagatt tgatagcatt cagcatttca
    32941 tcgaaatatt ttggagcaat ttgcatatag gaggaagtat gaatatagaa ttgaaagaaa
    33001 atttagaaaa aaattatgat gacaatgttt gggaacatgt gaccttggga gagtttgttg
    33061 cgaactgtgc ggaaacgtat aaagataaaa cagcgattgt agatggagaa ttaaacttat
    33121 cttatgatga gcttgataaa ctttcgaata agtatgctaa tggactactt aaagcaggtt
    33181 ttaaaaaagg agataagatt gtattacagc ttccaaattg ttatgaattt atagtgatat
    33241 cttttgcaat gtttaaaaca ggaattattc cgattatgag tttgcctgca catcgaaaga
    33301 atgaattaaa gggtattata gaaaagtctg aggcggtagc atatatttca aaggataaat
    33361 atttaggttt ttcatatgtg gatatggttc gggatatgaa atctgaatta aatacgaact
    33421 tggagattta tattcttgga gaaagtgaag aatataaaaa tttttcgtca cttattgaga
    33481 atgattgttt ctataaatat ccggatgtcg attacaggag cataggatta ttgttattat
    33541 ctggcggtac aacaggaata ccgaaactga ttccaagaag acattgcgat tatatctatg
    33601 ttgcaaagaa aacgacggac cggtgtaacg taaatcagga aagtgtatat cttgcttctt
    33661 tgccaatagc tcataatttt cctttggggt gtccagggat aatgggtact tttgcaaaag
    33721 gcggaaaggt ggttttgtgc aatgtgacaa gccctgatga aattttacct ttaattgagg
    33781 aagaaaaggt tacgataaca ggatttgttc ctgcaattgc caatatttgt atggattatt
    33841 tagagtatga agagtatgat ctttcctctt tggaggttat acaagtcgga ggttcagttt
    33901 tggaaccttg gttggcagaa aaaattgaaa aagtttttga tgttaaacta caacagattt
    33961 tcggaatcgc tgaaggattg atcttgacaa caaatgaaga agataacgat aaaataagat
    34021 ggcaaacaca aggcaaacca atcagtgaac atgatgaaat actgattgtg gatgaacaag
    34081 gaaaaattgt agggattgaa gaatatggag aacttatcgt tagaggtcct tataccattt
    34141 atggttatta taatcttcct gaagtaaatg aaacatgtat aacacaagat tgttatttta
    34201 agactggtga taaagcacga aaactaaaag atggtaatta tcaaattgtc ggaaggatca
    34261 aagaaatcat caatagagca ggtgaaaaga taacaccact tgaattagaa gaaattttgc
    34321 ttactcatga aaatatcaac tcggtacaag ttgtagggct gccagatcgt ctgcaaggag
    34381 aatccattgc tgtatttatt ttaaatggag ataaggagct tacactggaa gaagttagaa
    34441 aattcttgat ttctaataat gtggcggatt ttaaattgcc ggatactgtt aaatatattg
    34501 atgcgtggcc attaacagct ttagggaaaa tagatagaaa taaattaaaa gaaacttttt
    34561 aaaggaggat tttggaatgg aacttaacaa tataaaagaa agagctaaag aattagtaaa
    34621 ggattggttg aaaagtatat ttgtagagaa agtagtttca gaaaatgaaa atttaattga
    34681 aaaaggttta agttccattc aagtcatgca actgtctgga aaattaaaga aaacggggat
    34741 aaaaatttcg tttgcaaaac ttatggaaga accgaatttg tccaagtggt atgaacttat
    34801 tgataaatcc agagtgaaaa gtgataagaa tatagagtca tcaattatcc aaagtgatga
    34861 aagtaagttt gatttaacag atgtccagta ctcctattta atcggaagag aagatgatca
    34921 gattttaggt ggcgtgggtt gccatgcata tcttgaaata gatggagaaa atattgatga
    34981 ggataagtta aaagaggctt ggaataagct tcaatacaga catcccatgc ttagaacaaa
    35041 atttacgaaa gacgggaagc aggaaatatt atacaaaccg tacagtgaag aaatagaagt
    35101 ttttgattta tctgatcttg atgaagaaac gctgcatcta aaattagtag aaattagaga
    35161 acaaaaatct cataggaaat taaatgtaaa tcaaggtcag gttgcaggag tagcactagc
    35221 aaaattttca gatgagaagt caaggatatt ttttgacgta gatttgcttg tatccgatgt
    35281 aatgagcatg agtattatga ttaaagaatt agctgaactt tattcaggag tagaacttga
    35341 taatttgaat gagtatacgt ttaaggatta tatgcaaaac ggaattggcg aatcaatcaa
    35401 tgatgcagat aaggagtttt gggaacaaaa aataaattcc tttgaaatag aaagaccgaa
    35461 tttaccatta aggaaacagc cggaacaaat taaagaaacg aagtttacaa gaagaaagag
    35521 aattattaaa aaaagtgaat gggaaaccat aaaagatata gcagcatcgt atcgaagtac
    35581 accatctatg gttcttctaa ctgcctatgc tcttgttctt gaaagatggt gtaatcagga
    35641 taaatttttt atcaatatac cgctatttaa tagagattta gaaaatgaaa atctaaaaga
    35701 aatggttgct gattttacaa atattttatt ggtagagcat gaggctgtag atgattcaaa
    35761 ttttttagat aatttaaaga gaataaataa gacattcttg gaaaatgtat ctcacagtga
    35821 gtataacgga gtgcaggttc aaagagatat atcaaaaaaa caaggtacaa gtgtgtatat
    35881 agcacctgtg gtttttgcgt gtaatataga ttatccattg gaaactgaat tttcaagaaa
    35941 aaatttaggg aaagtatctt atatgatttc tcaaacacca ggagtttggc ttgattttca
    36001 aacatatatt gtagatggag atttaattct ttgctgggat agcgtggatg aactttttcc
    36061 aacaggaatg ttagaagaca tgatggattc tttatatgaa ttgatcatat ctttaacaca
    36121 gaaggaagaa tgggaaaaga aagtagatgt tttacctgaa aagcaaaagt ctattagaat
    36181 gcaggatgtt gagggaattt taccacttca atatcctagc gaaacgttat atgacggatt
    36241 tctcagaaat gtaaaactca atccagatag agttgcgatt atagattctg aaacgaagga
    36301 agagataaca tatcataaac tttatgaaat ctctttaaaa gttgcggatt gtttaggtaa
    36361 aaatggtgtt aaaaagggag attatgtagg aataacactt ccaagaggta gcagacaact
    36421 ttatgctatt tttgggattt tatttaccgg tgcagcatat gtatcaattg gtattgctca
    36481 gccaaatgat agaagaacta aaatttatga tcaaatcgga ataaagtgca ttataagtga
    36541 tgaaaagaca gtgatagatt gtaaattaaa taaaaatgaa gttaaaatta ttgatttgga
    36601 tgtagctatg gcaaatgtgg ctaaattaaa gcaacctgtt gaaattagcc cttatgatag
    36661 tgcgtatatt attatgacgt ctggaacaac aggtgttcct aagggtgttg agattatgca
    36721 tacaagtgcc gttaatactt gcattgattt aaatgaaaaa tacaatgtaa atgctgaaga
    36781 tacaatactg atggtgtcgg caatagactt tgatttgtcg gtttatgata tttttggaat
    36841 acttcatgct ggaggaacgg ttattacaac aagtgaagat aattatagaa atcctgatga
    36901 atggttaaat ttagtcgatg aatataaggt tacaatatgg gattctgtgc cgattttgtt
    36961 tgatatgatt gttactatgg ctgaaggtaa aaatagaaac ttacctttta gaattgtgat
    37021 gctttcaggg gattggattg ctataaattt accagaaaga ttctataata ttagtgaaaa
    37081 tataaattct attgttgtcg ctatgggtgg agccacagaa gcatctattt ggtcaaacca
    37141 tttgaatgta ccaagaaaaa taccgaaaga ttggatttcc attccatatg gtagaccttt
    37201 gaaaaatcaa gtgtatagag ttgtggatga atttggtagg atctgcccta attatgttaa
    37261 aggtgaactt cttatcggtg gagttggtgt tgctaaatgt tatcatggtg acgaagaatt
    37321 aacgaataaa aagtacttcg aacaagatgg gatgaggtgg tatagaactg gagataatgg
    37381 tagaacatgg aatgatggga ttattgagtt tcttggaaga aaagatactc aggtaaaagt
    37441 taaaggacat agaatagaac ttggagaaat agagaatgct ttaattgtat ttgaaaatat
    37501 aaaaaaagcg atcgctttaa ttgttaaaga tggaaatgtt aataaacttg taggatttgc
    37561 ggaaatattt gattgcaaag aaagtaatca aatgttattg aattcagatt ttgaaaagga
    37621 gactgaagaa tataaaaaac agaaggatga atatattaat ttcatagatg aattgaactt
    37681 taaggtaaac agaataattt ttaatgttat tcgtaaatgt ggtgtatttt ctgatgagag
    37741 ttatataacc ttagaagata ttatcaagaa aatcaatccg atagattcac tgaaaaatct
    37801 aataaaatct tggatatata atttgtgtga agaaggtcta ataaaaagga acgatagcaa
    37861 taattattgc ataagcaaat ttatgtgtga tgatgaaaaa tatgatgtga taaaaacaaa
    37921 agaaaaggat atagaattaa atagatattt acaagtatta gagacttatc tgttggaaat
    37981 gatacaaggg aaagtaaatc caataaattt cttctatact actaatccgg aactatcacc
    38041 gattagctta agtaaattat taccttggca tgaagatgta atggaatgta tattcaacta
    38101 catagaaatt gatgttgatg gtaatgataa agaaaatata attttagatt atgattcaaa
    38161 gaatgatttt ttgagtcaaa gaatagatga aatttctgat agatgtgttc atttacattt
    38221 tgataaaaca cttaatgtca taaataaagt atcaggtgat tttaaaaatg aaaatgattt
    38281 tgaatctcta gaaaataagt tggattatat agtggcattt aattcaattc ataggacagt
    38341 taatattaag gaaacaatga aaaagttgag aaacttgttg actaataatg gcaaactcat
    38401 agttgtagag cctaaagaac gaatacgcat tcaagatata actacaagta ttcttaataa
    38461 ttttgccgga tataatgata atatttttaa tgttgatgaa tggaatagta ttttttacga
    38521 tgcaaatctt aattgttgta agcaaa
//
LOCUS       DARYLJ010000018        38044 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYLJ010000018 DARYLJ010000000
VERSION     DARYLJ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38044
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(80..1285)
                     /locus_tag="TU746_000803"
     CDS             complement(80..1285)
                     /locus_tag="TU746_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL0891168.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TU746_000804"
     CDS             complement(1538..2791)
                     /locus_tag="TU746_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0891169.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TU746_000805"
     CDS             complement(3188..3808)
                     /locus_tag="TU746_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891170.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TU746_000806"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TU746_000806"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TU746_000807"
     CDS             4121..5347
                     /locus_tag="TU746_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL0891171.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TU746_000808"
     CDS             complement(5457..5951)
                     /locus_tag="TU746_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL0891172.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TU746_000809"
     CDS             complement(5948..6730)
                     /locus_tag="TU746_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0891173.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TU746_000810"
     CDS             complement(6829..7368)
                     /locus_tag="TU746_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL0891174.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TU746_000811"
     CDS             complement(7372..7683)
                     /locus_tag="TU746_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891175.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(8070..8207)
                     /locus_tag="TU746_000812"
     CDS             complement(8070..8207)
                     /locus_tag="TU746_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0891176.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(8591..9835)
                     /locus_tag="TU746_000813"
     CDS             complement(8591..9835)
                     /locus_tag="TU746_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0891177.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(10264..11406)
                     /gene="tgt"
                     /locus_tag="TU746_000814"
     CDS             complement(10264..11406)
                     /gene="tgt"
                     /locus_tag="TU746_000814"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL0891178.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            11811..12656
                     /locus_tag="TU746_000815"
     CDS             11811..12656
                     /locus_tag="TU746_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL0891179.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(12852..16814)
                     /locus_tag="TU746_000816"
     CDS             complement(12852..16814)
                     /locus_tag="TU746_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL0891180.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(16949..18775)
                     /locus_tag="TU746_000817"
     CDS             complement(16949..18775)
                     /locus_tag="TU746_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL0891181.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKA
                     ADKQQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(19135..19608)
                     /gene="perR"
                     /locus_tag="TU746_000818"
     CDS             complement(19135..19608)
                     /gene="perR"
                     /locus_tag="TU746_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL0891182.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(19645..20097)
                     /locus_tag="TU746_000819"
     CDS             complement(19645..20097)
                     /locus_tag="TU746_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL0891183.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(20337..22979)
                     /gene="polA"
                     /locus_tag="TU746_000820"
     CDS             complement(20337..22979)
                     /gene="polA"
                     /locus_tag="TU746_000820"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL0891184.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(23403..25133)
                     /locus_tag="TU746_000821"
     CDS             complement(23403..25133)
                     /locus_tag="TU746_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL0891185.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(25151..26347)
                     /locus_tag="TU746_000822"
     CDS             complement(25151..26347)
                     /locus_tag="TU746_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL0891186.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(26547..26789)
                     /locus_tag="TU746_000823"
     CDS             complement(26547..26789)
                     /locus_tag="TU746_000823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891187.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(26854..27945)
                     /gene="ulaG"
                     /locus_tag="TU746_000824"
     CDS             complement(26854..27945)
                     /gene="ulaG"
                     /locus_tag="TU746_000824"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL0891188.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(28140..29786)
                     /locus_tag="TU746_000825"
     CDS             complement(28140..29786)
                     /locus_tag="TU746_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL0891189.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(30090..30806)
                     /locus_tag="TU746_000826"
     CDS             complement(30090..30806)
                     /locus_tag="TU746_000826"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL0891190.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(30806..31669)
                     /locus_tag="TU746_000827"
     CDS             complement(30806..31669)
                     /locus_tag="TU746_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL0891191.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(31674..32339)
                     /locus_tag="TU746_000828"
     CDS             complement(31674..32339)
                     /locus_tag="TU746_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL0891192.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(32434..32919)
                     /locus_tag="TU746_000829"
     CDS             complement(32434..32919)
                     /locus_tag="TU746_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0891193.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(33135..33413)
                     /locus_tag="TU746_000830"
     CDS             complement(33135..33413)
                     /locus_tag="TU746_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0891194.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(33528..34961)
                     /locus_tag="TU746_000831"
     CDS             complement(33528..34961)
                     /locus_tag="TU746_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0891195.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(35444..36064)
                     /locus_tag="TU746_000832"
                     /pseudo
     CDS             complement(35444..36064)
                     /locus_tag="TU746_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(36066..36683)
                     /locus_tag="TU746_000833"
     CDS             complement(36066..36683)
                     /locus_tag="TU746_000833"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891196.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(36670..37458)
                     /locus_tag="TU746_000834"
     CDS             complement(36670..37458)
                     /locus_tag="TU746_000834"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891197.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
     gene            complement(37529..37930)
                     /locus_tag="TU746_000835"
     CDS             complement(37529..37930)
                     /locus_tag="TU746_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891198.1"
                     /translation="MKLGKIKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGR
                     TKDYLVKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDT
                     KSGYLYALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT        10983 a         8908 c         7422 g        10731 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgctcctc tcttgcgctt
     2821 tgtattttgc ctttaaacac taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaaa caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc taaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatca cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 taatcgtcga cctaccaaag ttcagacggt tattttttat tgtttaatat gacgattgca
     8101 acgactaagc tgattaaggt aagtaagaaa ctaccaaaag ccagcatgag ttgaagggcc
     8161 tcgtaagtag acaataaaac gctcctttct gttggatttt gatgcattgc ccataggtat
     8221 caccaccttt cagaaatcag agccaccgcc ttagcttttc tgtaaagaac attattatat
     8281 cataatcaca caagaatccg tcaaatctta aactaatcag gcggcttttt tatgctctga
     8341 ctataggtct gaagagaaga tgctagatgt cttaggtggc tttccattta aactacgagg
     8401 tcttctttct cacagagtat agccccctct tttttcagct actgtttcgg aggcaagctg
     8461 gcatttcgtc taaattgctt ttgtttttcc ctgagcattc gaaaaaatcc tttatttcta
     8521 cctgacatat cactaaaaga gggtcctgtg accctctttt atagctatct gttagagaga
     8581 tatgcaattg ttagtcttgt tttttcttca agcctaggac acctgcgcta gcaatgacgc
     8641 tgagagctgc aagggtgaaa aatgggtgat ttgcctcccc cgtagctggt agcgtgccct
     8701 tttgagctgc tggagccgct gatttgtttg gtgctgactg aggagctggt gcctttggac
     8761 tagctggctg ctctgaagat tttggtgcct gtggagcagg ggattgctcc ggtgcctttg
     8821 gagtctctgg ttcttttggt gcttgtggtt gctctttttt ctccggtgtt tctggagcct
     8881 ttggcacttc tggcaccttt tgtgattccc cttgttgacc tggcactcct tgtggcccag
     8941 tatcaccttt tggaccttgt tgacctggtg cgccttgtgg gccggtgtcg ccttttggtc
     9001 cttgttgacc tggtgcgcct tgtgggccgg tatcaccctt tggtccttga agtccctgtt
     9061 cgccttgtgg cccagtgtcg ccttttggtc ctggttgacc tggctctcct tgcgggccag
     9121 tatcaccttt tggcccttgt tgacctggtg caccttgtgg gccggtatca ccctttggtc
     9181 cttgaagtcc ctgttcgcct tgtggcccag tatcaccttt tggcccttgt tggcctggcg
     9241 ctccttgagg accggtgtcg ccttttggtc ctgggagacc tggttcacct tgtgggccga
     9301 tgtcaccctt tggaccttgt tgacctggct ctccttgtgg cccagtatca ccttttggcc
     9361 cttgttggcc tggttttcct tctggtccct gtgggcctat tggtccacgc tcaccaactg
     9421 gtccgcgttc ccctcgaagg ccttgaggtc ctgcgggacc cattggacct tgaggtcctg
     9481 gtatccctaa tgaatctttc tcatacaatt tgtataattg ctctgattgg cctgtcgatt
     9541 tttttaaaaa ttgctccact cgccatagat atcttaaaac attttctagc attcgaccat
     9601 tgttataatg tgtcgaagtt tcccagtcac ttgagctacc agaaccagga ttaagtattt
     9661 ctttttttat gaactgttga aagaaatatc cttgattata catagaagga tatgtaaagt
     9721 cttctgccct tacatcattt ccaatcccta agctagctat ggttgctagg gcgacaactg
     9781 ctgagcagat accgtacttc tgaacaagcc tgatacttgt tttcttgttt ctcatgttta
     9841 tctcctttta gtttagaaat gttaacgatt tctaatcttt tttcttccaa agaaaatctt
     9901 aacatgacgc ttgcgggctg tgaatatgtt ttggggaatt cgcttccgta gtttcgtttt
     9961 tttctaatca aagggtcaat tgtctgacgc tagtgtcttt tggcattggc ctttagctta
    10021 ggaagactgc ctatgttagc aagcttttca ttagcttatc cgttttgata aagggtaagc
    10081 gacgaggata atctgacttt gtcttttgct tttgttagat tttttaatgt tttttgatgt
    10141 ctgatgactt ttaaaaaaag ccttcttttg ataggcaagc ttaaaaggcc taggcaaaag
    10201 cccagaccct tgctgctatt atctgttatt gtggaaagct accgctcttt ggcactgtca
    10261 tgcttaaaaa ttgcgacttg agctattgta accatagcgc tcaaggaaat cctgacgaaa
    10321 ctctaaaagg ttatcgtcca agatagcttg acgcacctgc ttcatgaggt ttactaagaa
    10381 gtataggtta tggtaactgg tcaagcgcat gccaaaggtc tcatcagcct ttaagagatg
    10441 acgcaggtaa gcacgtgtgt aatgctgaca ggtgtagcag tcacaatgat ggtcaagtgg
    10501 ggtaaagtcc tctgcaaact tagcattttt cacaacgaga cggccctcgc tggtcatgca
    10561 ggtgccattg cgagcgatac gggttggcag gacgcagtca aacatgtcaa ccccacgaat
    10621 caccccatca atcaggctat caggtgcacc tacccccatc aggtagcgtg gcttattttc
    10681 aggtaaaagt ggcgttgtaa aatcaaggac agcattcatc tcagcatggc tctcaccaac
    10741 tgccaagcca ccgatagaat agcccggaaa atccatgctc acaaggtccg cagcagattg
    10801 acgacgcagg tcctcaaagc cagctccctg cacgatacca aagaggcctt gatcatgagg
    10861 acggcggtga gccttcaagc cacgctctgc ccaacgactg gtgcgctcaa tggatttttt
    10921 cacataatca tagggctggt aaaattgcgg gcactcatca aagctcatca taatgtcaga
    10981 ccctaggtta ttttgaatgg agatcgcttt ctctggtgat aaaaacatct ttgagccatt
    11041 caggtgattt ttaaaggtca ccccctcctc agtgatgttt ctggagtctg ccaaggaata
    11101 aacctgaaag ccgcctgagt ctgtcagaat tgcctgatcc cagttcataa atttgtgaag
    11161 gccgcctgca cgcgcaatca gctcatctcc tggtcgtagc cataggtgat aggtatttga
    11221 caaaataatg cctgacccaa tctccttgag ctcctcagga gactgtgtct taaccgtcgc
    11281 ctgtgtccct accggcataa acatgggcgt cggaaaggtc ccatgcgggg taataatctc
    11341 accgagacga gcacctgtat gcttttcctt tttgatcaaa cgataagtaa tagggtaatt
    11401 agtcattgtt tcttttttcc ttgctatcaa gataaacagt cttgagcgtt ttgcatacca
    11461 cttacaaagc acttagtcaa gcggtatggg cttgtttaga gccctatcat tttatcaaaa
    11521 aatctctgac ttgtcatgcc ttcaaagaga caagatcccg aagcaatggc acgacagacg
    11581 catgaaggag ttttagcaag aaaagaaagc tttctgtcgt tcaatgttca gctatttcaa
    11641 gtatatgtct tatcttttat aaactttact acagaaaaat cgttgaaaat gtttgcttta
    11701 ctctatacta tcattcagaa atagctgttt cgcgcgtttg tcgtgagcaa ggacggtatg
    11761 ggtatcactg gctcctagaa tatggtataa tgtaccaaag gagttgtacg atgtcaatta
    11821 gagaaataaa acgtgaagct agacagactt taaagggact aaaggggaaa tacctcttat
    11881 ttttagtacc gataatctta tctatttttt actcaggaat tgaggttcat cagacctatg
    11941 tgaccactca ggggattgag gtatcagtcg gggcaagcta ctttcctttg attgttctga
    12001 taatgctgac ggtctttacc ttatcagcag cctataccat gctagatgtt atccgctact
    12061 atcgtcgtga ggtctctttt tcagaggcaa cgatagcttt ttctggaaac ttgtttggca
    12121 aggtccttgt tttgttgatc atcaaagggc tcctatttat cctatggtct ttgatttgga
    12181 ttgttggctt ggttattcta acgattagct ctgcggcatt actgacaagc tacaatactg
    12241 gtgctgctgt gatgactcca atcatcttta tggttattgg ttttgtgatt tttattatcg
    12301 ggcttattgt ttatatgaat cgttattgtg cttacagcat ggctgagtac attctctatg
    12361 acaaggtcaa ggaaggcacc tatatgggtg ctattacggc aatcgaagag agcaaggaca
    12421 tgatctcagg ctataaagga aagtattttt tactacacct tagctttatt ggctggttta
    12481 tcctagtaat cttgtctttt ggcttgatct atatctacgt actgccttat tacaccactg
    12541 ctgatgtgac cttttaccac catttaaagc acattcacga tgaaacagag ctgccgatag
    12601 atgctgaaag gcttactatc acaggttcaa aagaagcccc atctgctatt agctagcctt
    12661 aacgatatgc ctctatgtct ctcatgacct tgttcagagt agacatagag gttttttgca
    12721 tgacctttga taactttttt atagtaaaaa agaggagccc atcagttgcc tatccaaagc
    12781 tagatgacac atctaacggt tggaaggctt gcttacaggc cctcttttag caatgttagc
    12841 ccaagactat cctaaagctg ctgaaaagct cctcggtcta aggcataggc agtcgtccaa
    12901 tggctctcac gatagtaaat aaagagctgg ctatctaata gctcatcaat tgaggctgct
    12961 gttggcagac ctgctaggtc aatgaaataa tcccctggaa gaagctgttg tagcttttcc
    13021 attaaggcgg tattaacagc ggtctttgct gctggtaatt gactagagat tgataagcct
    13081 tcaaaggtct ttaaatctat gttttctgac tctaaagctg attttaaggc tgatttgatc
    13141 aagtctaggc tgtattcagc atctaaggct tcatcgcctg atgagaggct attcatcgcc
    13201 aatacataca aagggcctgc tgccttatcc tgataggtaa tgacaagttg atggttcagc
    13261 aaatcagcta agtcatcata agtaccagtg ttctcaagag taatgtaata agtccctgtg
    13321 agccctaagt ccttgattgt ctctaaaatc ttgccttgga ttgcttgatt tttttcagtt
    13381 gttgccgctg ttagaccact atttgtaata gcaaagctct caatctcttt ggtagctgta
    13441 ttggtctctt ttagaatggt tagaatacta tctttaagcg ctagaatatc atttctaacc
    13501 ggtgcttcaa tagggctaga gatgtcttca aagaaacgat aagcagaacc gctgacaaat
    13561 ttattggcct gtccgctgct ttttccatag gtgtctaagg cagttattct aacaaatcga
    13621 cctgttgttg gtgtaaagct gactgttttt agctcagtat tttgcttcca atcagtgcta
    13681 tcgacaaccg ttgtccagac cttaccgtct gagctgatgt cgacctttgc agaatggatc
    13741 ataccattaa cacctcctgg gagataggca atagcagaga agtttttatc gtccttaaac
    13801 tcaacagtat atgacttgtc ctcagtaacc tgattaaata aggtatgcca ttgggtggcc
    13861 atatctctac catctaccat atgcttgcca gacctgcctg attgctcatt agcataggtc
    13921 accgcctgaa tatcatcaat tgagatgtag tgcattgtag gatcagtgct gtctgcggta
    13981 aaggtatagg taacgctgtc acttgctaga ctggtgccat gagcccgata gcgagcaaga
    14041 actgtgacag tgtcattgaa gcgctctgtg ccatcataag cctgccaaga ctggccatta
    14101 tccagactga cctccaaatg ttcaatagca ccaatcaagc gattttccaa gtcattgcca
    14161 taaaggctgc tgttggtcgg tgctgctgcc tttgtcaggt taatcctgta ggtagcagat
    14221 accgcgtcaa agccaactaa aataccgtcc tctatattaa gcttggccaa aaggtcatca
    14281 ctaaaaacga taaccttgtc cttggtttca agccatgttt tcccattatc aatagaatag
    14341 cggactgtca aatctgtatc ctgataattc tcatgcaaac gaagggtctt gtcatcaaag
    14401 ctaaagcttg ctgtttcgat tggattgccc gttaggatat agttggcgat aattctaacc
    14461 tcattagatt ggagcacttc cttatcagtt gctgttttgg ctgcgattag agcgttatag
    14521 ctcagtaaat ctagctcagc cttagctgct tgatcgctga tattaggcgt gatacgcttg
    14581 atagcctcta ccatgacctg tggatagtag gtgtaagctg caatgacacg ctttcctaag
    14641 tccagccaat cctgatctgt tttttggcca ttttttgcat aggcctctat caagccatcg
    14701 taagtatcta gattaagctc tagtacatct aaagccttgc tgtaggcctc aatctgttga
    14761 tcactgccag cctcgtagac attagcgatg agattataat aaagcgattc cttgaactta
    14821 tcgtattggt ttaaggctgc ttgcgccagc agcatatagc tagcgttttt atgaatgtca
    14881 ttgtaggatt ttaggcccca gccaagcaag agcctagcct ctgttgctgt tgtggttccc
    14941 caacgagaat aagagattgc ccagcgatta ccataaacat tgtctctaat atcccaaatc
    15001 ccgttgccct gatcatcttg acggtaaacc aaataagcct cgtggtcatt ttggtaaata
    15061 ttgaccgctg gaataccaaa gacctcattg actgctacac ctaaatttga taatccccag
    15121 caaacagccc ctttttccat cagcatccag atccggtgac ggttgtcata agtaacatta
    15181 aaggcatcgt cattgagggt gccaacgagc tgatattttt ctgtccattg agcttgattg
    15241 tcagcgctgc gcatgtctgc gccaccgtag ccgatgtttt tgtatttcgt ataagagtag
    15301 ccactggtat agctagcaac cttatctcca tatttttgtt cggcgtaatg atgcagccag
    15361 agaatttcct catcatctat tttggcgtcc ataacagcac gcaccaactc catattgtag
    15421 ttggcgaatt cttctttcct caagaattcg ttgtctcgat acaattcttt aaaggcttga
    15481 tatttcagca ccgggtcaga agcaaggtag gtgccaccat agttaaccac aaaggatttg
    15541 atctccttgc agtaggcaac agcagttgcc agcatcattt ttttgtagac atagccattt
    15601 cccttgtcct ccaaatctgc cttattagta gcataaaggt ctcctaaggc gttcaaggtt
    15661 tttagggtag agccgttaaa catcgagcct gcctctaaaa acagtgacag agcgtcctca
    15721 tctgacaata gccaatcaag agcgaccttg accttttcat ttttcttgac agcagattga
    15781 atggtgtggt agccgacacg attgacaaat tcgcgctcaa gcactaatgc caaattgtct
    15841 ggattatcat aattatctgt gacactattc ttgctgagaa gggcatcata ctcttcagtt
    15901 gtctttagcc tgtcataaga cacctcgctt gataaatcat aatctgtctt gagcaacctg
    15961 agatccgcat aaacagagtg atcattaccg ttatttttta gtgaatttgc aattagcttt
    16021 acatatttag cacctgtaat atctagatca acataaacag cctcactggt tccggttact
    16081 gtaccagttg tcaccaggct ttcccaactt tttccgtcct tagacttata gatgttaaag
    16141 ctaacaccat cgtccttacc acgtctacta tagtcaactc ctaggtaggc tgatagacgc
    16201 gtgtattcat tggagtattg ttcaacatca taataaagct gtgaaggagc atgcactgca
    16261 attcccttat caaatgcaag cacctcgcca tcaactacta gagtaatggt gccaccggca
    16321 gggtttttgt cctgtaaaaa gctgccatgc ccaaccttgg acgggttgac acgtgtctca
    16381 tctgataagt agatatagtc cttagcttca gtcttattgg tggtctctac tgcttgtgat
    16441 acttctgtct gctcctgctt tgtggtctct tcggcagaag cttcggtagc ttgctctgct
    16501 gcggctactt gactcttaga gtcagttgtt tctgtagtgg cagtacctat tactactggc
    16561 agcgtttctg aggagccctc agctgctgtg tcttgcgcag cggttgctga ttggtcagct
    16621 gcttgttgat caaccgcttc ttgtgcttct aacgtggttg ctatggctgc actagctgtt
    16681 acttgctgct catcagcaga aacagttgtc agccctagtg ttaaaaataa ggttgcaacc
    16741 aacacagagg ctgcacctgt tttaaaggtt ttaatggcaa agcgctgctt accatcagta
    16801 taaggtttga acatggtgtc ttctccttta aaaataagat atttaagcaa aataaagact
    16861 gaccaccaac cactacagtt gataatcagt ccaacaaaga tatcgtacta taggaaatta
    16921 attaaagggg gaaaatcatc gcctacagtt aatttgattc tttgcgtctt gacacaatag
    16981 caagctggcc tgcacaagca ataactgcaa gagctgctgc tgtaaagaat ggattagctg
    17041 tatcagcagt tgccggaagc acttgctgct tatcagctgc tttcttgtcc tccttcttag
    17101 cttcaggctt agattctggt ttaggctctg gcttaacctc aggatctgat ggttttactg
    17161 gatccgctgg gtcgattgga tcgaccgggt ctaccggatc cactgggtct accggatcca
    17221 ctgggtctac tgggtctact gggtctactg gatccactgg gtctaccgga tccactgggt
    17281 ctaccggatc tactgggtct accggatcca ctgggtctac tggatctact ggatcgaccg
    17341 gtttagcaac caaggctgcc ttggcatctg agagggattt cttagcattt aacaccttaa
    17401 ccaagctgtt agtaatagct gtcggttctg tctcctgagc ataagctgtc tcacccgctg
    17461 ctgcgacctc cttagcctta gctagctggt ctgtataggc ttgagcagaa gctgctgtat
    17521 atggagatag gtctagattt tctccgataa gagcatttaa ttggtctaaa gcagaacgca
    17581 attttgcctt tccttcttcg gcaatcgcag cctttacctt taaaatagta tcaacaactg
    17641 aatttgtttc tgtagtgtag cgctctagct cataaaggga aatgtctttt ctctctttat
    17701 ccttgttaac agttctatag aaggtacctg ctgcttcaat ggccttattg tacaattcct
    17761 tcaaagactc tgatgtcaaa gcaagatttg gattttctcg gtaaagctct aacagcttag
    17821 ccaaggcttg atctaaggct tcatgcgcta cagcagtctt aagcgtcgta agagcttgcg
    17881 ttaaatcagt cgcagcctta tcaacatctc cttgtgaagg accaaatgaa ttttgaagct
    17941 tagctgccgc tgcaagcttt tgcacaagac cgtcatacgc ttctttagga tactctttgc
    18001 catctgttat aaaaggtgta gcttgattaa tagcttcatt taaagcatta agattaacaa
    18061 gactagtaat agcggaatca atagtagtaa cagattgatc tactgtattt tgatcagggt
    18121 cactgtttaa ataggtctta ccaatagtaa ccgctgattg caaggcttgc agtgattcat
    18181 cagaatacgt tccttcaggc tggctgagtt ttagcttagc ctcctctaac gacttcctta
    18241 actcagtttt attgctgttg gaatttttta gtttaaatgt gaagagcttt ttggtatcat
    18301 ttttcccata gaatacccaa gctttaatag tataagatcc ccccggtaca gcatatgtag
    18361 gcgaagctaa catttcatca gttaaaaagg aagtacccgc agcattgtaa aagtcaaacc
    18421 atatttttac tccaggggta tcaattcctc ttgaaccatc tccattcgaa ataaagtcaa
    18481 aagtatctcc atcattaaca gtcccattac tacctttacg agtaaccgta atttgactca
    18541 taagatctga gatagtaatt ggttctccta attcaactgt atattcttgt ggaatatcta
    18601 tgtgccagtt cagatgttga cctgtcccat tattttcaaa tgcactagca gtagtcgttt
    18661 ccgcccctac tgttaaagcg ctatcaatat tatccgacaa ggcaaccaat cctgtgctga
    18721 aaactaatcc aacaagacca cagcccttaa gacaccgttt cgtgaatttc ttcattcttc
    18781 tttttccttt tctagagccc tagcaggctc gaacaatagc aatatgtgtc atagggcagc
    18841 tgctatcact agtagctgcc actttgatat tagcctgatt gtgacactca aatatcactt
    18901 ataatttaca aaaaatttta agaaaagtca atatacaaac ggtttttgtt aaatttttta
    18961 aaaatataac aaaaaacaag cacgccaatc tggtctataa cagtttttat tgtcaatagt
    19021 gatcgctaaa gggtttttca gccaacaaaa aaagagtgag tccctaactc tctcttctag
    19081 actttgtgcc atatcatcag ctacacgaac agccaagatc aaaaaggcca gctctcaata
    19141 gtctgtgtcc ttaccctgct tcgtctgaca gctagggcaa acaccatagg ctataactgg
    19201 aatacgggtg accttatagc ctgtttgctg gtgtgcttcc ttagcgatat ccatcacatc
    19261 tacgtccata aaatcagcga ttgtcccgca aacctcacaa accacattga catgctgatg
    19321 tcccataaag tcataatagg tcgtcaaatc attactaatt ttcagctcgg atacaaagcc
    19381 ctcatcaacg agaaccttca aattattata caccgtagca aggctcatat tagggtattg
    19441 aggctgtaaa tcacgataga ttttatctgc gctggggtgc tcagtggact gaatcatgta
    19501 agaaatgatc gccttacgcg tctcggtaat acgaatatgc ttgtcacgta gatgctctag
    19561 gacattttca taggcattta gagcttgctg atgtgaatga atgtccaagc ttacaacctc
    19621 ctccttttgt aactatggca ctaactagca ggaatcttga tcctgcttgc tgattagccg
    19681 taaatagtca atcttgatac agcgattcat aacaatgtca gctttgcctg ctgatcgcaa
    19741 aagctcctca gcttcttggc tatacaagcc aagctgtgcc caaaagacct gaccctgaca
    19801 agctaaaaag tcctgagcaa cctgaggcaa atactcactt cgtcgaaaga cattggcaat
    19861 atctacctta aaaggaatag ccgcaaggct agcataaacg acctctccta aaacagactg
    19921 acctgccagc ctaggattga cagggacaat ccgatagccc ttagcctgca taaacctagc
    19981 cacatcataa gcagcagtgg tttgacgatc agataagcca accactgcaa tggtcttgga
    20041 agattcaaga taagaggtga tagtctcatc agagggattt tgaaatgtat caatcatcat
    20101 ttacttcctt tttatcaagc acacccaata gcaaatcaac aacaggaaaa gacaatcgct
    20161 gccggtatga catagccaac catctggcta ccaagctcaa ggaaaaccct ccttagcatg
    20221 acatgccctg ctgttttttt ctcttcatta tagcataagt ttttaaaatg cggaacacaa
    20281 ggaataacag cagccacacc aagcaggctg ccacttaaca ccactgctaa tctagtctac
    20341 ttggcctcat accagctctt gccggcactt tcgtctacac gcagcggaac tgccaggctg
    20401 acagctgatt ccatcgtttc tttgaccagc gctttaacag ccgctagctc atgattaggc
    20461 acctcaagca caatctcatc atgcacctga agcagcattt tggtctcaaa gccaccagct
    20521 actagggctt ggtcaagatt tatcatcgca attttgagaa tatcggctgc actgccttga
    20581 atgggcgaat taatggctgt acgctctgca aaggagcgaa cgttgaactg acgagaattg
    20641 atatctggca attgacgacg gcgcttaaag agcgtctcaa catagccctt atccttggct
    20701 tcacgcacaa ccctttccat gtaagccttg ataccagggt agcgctcaaa gtaggtgtca
    20761 atataagcct tggcctgttt tcttggaatt ccaaggttat tagacaagcc aaagtcagaa
    20821 atcccataca caatgccaaa gttaacagcc ttagcattcc gacgatcatt ggcagtgacg
    20881 tcctctggct tttcaatgcc aaagacacgc attgccgttg aggtatggat atccgctccc
    20941 tccttaaaag cagcaatcaa atgctcatct cctgaaatat gtgctaaaac acgcaattca
    21001 atttgcgaat aatccgagct aagcaaaaca gcatcatcat gagatggagt aaaggcctta
    21061 cgaatcaagc gcccctgctc cagacgaatc gggatatttt gcaggttagg atcaacactg
    21121 gaaagtcggc ctgtctgggt taaatcctgt aaatagcggg tgtggatcct gccatcagcc
    21181 atgatgtaat cctgcagtcc aatcacatag gttgattgca gcttagtaat ttgacgatag
    21241 tccaagatct tagccacgat tggcgcaatt ggcgctaagc gctccaagac atcaacagcc
    21301 gttgaatagc ctgtcttggt tttctttgtc aaatgaagag ggagctgcat tttctcaaag
    21361 agtatcactc ctagctgctt gggagaatta atattaaaga cctcaccagc catttcatag
    21421 atttcctgtg tcagttcctc aatgaccacc ttattttgct ctgccatttc ctgcaggcta
    21481 tcttgattga cagcaatgcc ttcgatttcc attttcgcaa ggacattggc aagcggcagt
    21541 tcaatgtcag tgtagagatc agcctgctca tgctctgcca gcttatcaag catgactggt
    21601 ctactatcca gcaagacctg aaccttacgc gccagatgtc ctaacaaaac agccttgtca
    21661 ggcacagcac gcttgacccc cttaccatag acaacctcat ctgtatccag tgatatagtg
    21721 gtataaagac gtgccagagt agccatctca ttgtcctcta cagttgacaa gaggtaatta
    21781 gctaagcggg catcatagct ggcagccggc aaatcaagcc ccagatgact aagcagaacc
    21841 ttactgcgct taaaatcata ggtagcaatc ggctgctcaa gaaccttttt aaagagcttt
    21901 gtagtgagga gactaatatc tgctgaagca taaatctggc cttggttgcc ccaagcaaag
    21961 ccaatcagct cctcgcggtg ataattatcc ctcaaagctt caaaataaaa caccgtatcg
    22021 tctgaaaaca tgtccgctct tatgtcagta acttcctgat aagcaatctc agctaccggc
    22081 tcctgtggca actgactagc taaggcattt tttagttgaa caaaatccat ctcatcataa
    22141 aattgtgaca agcgatctag atctggaccc tgatagacaa tatcctccaa tccaatcgta
    22201 atcggagcgc tagtgttgat agtagcaagt gtctttgaga ggaaggcctg ctccttatca
    22261 tgaagcaggt tttccttcat ttttgaaggc ttgaagctat caatatgctc gtaaatcccc
    22321 tccaagcttc catattcgtg caggagcttt agacctgttt tttccccaat tttggtcact
    22381 cctggaatat tatcagactt gtctcccatg agcgctttca agtcaatgaa ttgctctggc
    22441 gtaagcccca ttttgtccat aaggtaggct ggggtaaact cttcaaattc agcaactcct
    22501 tttttagaaa tctcaacaac ggtatttgca tctgtcagct gaatcaaatc cttgtcacca
    22561 ctgacaatag tcacatcaaa aggaatctct gtacgctctg ccattttatc aagcgttccg
    22621 ataatatcgt ctgcctcgta atgctctagc tcataaaagg caataccaag cgctcccagc
    22681 atatcacgaa tataaggaaa ctgctcccga aattcatcag gggtcttggc acgtcctgcc
    22741 ttgtaatcag caaaaagctc tgtccgaaag gttgttttac ccgcgtcaaa ggccaccaag
    22801 acatgcgtcg gctgaacacg cttcatcatg tggtctagca tcaaatgaaa gccataaatc
    22861 gcattagtgt gaagaccgct gtgattttta aagcggtcaa tctggttata gagggcaaaa
    22921 aaggcacgaa aggccactga ggagccatca atcaaaagta atttattctt gttttccatg
    22981 cctttattat accacacagt gacctgcttt gctctgacca gctacgcttt ttgcaagcac
    23041 tagcaggtaa agcagcatac ccgtagcttg atcaaaagat ccaagctgct tgaaggaaga
    23101 taaatgactg cttttgcttt atcatcaaga catttctacc aaaaaagaga ctgagataaa
    23161 aagagtgaca ctttagagag tcttaactaa tatcctttgt tatctaattc attaacaaac
    23221 gaacaggcct agttttcaaa acctcagaaa actaaacctg ttcatttgtt ctatttgaag
    23281 tcagactttg tctcaatctc caaattgatg acatcatctg ctatgacttt cctaagctga
    23341 tatggacgga aagccttctg caaaatccat gattagtcta ggctacattt gagcgagcgg
    23401 ccttatgact gagtccattt ggccacctta tcagcatggc tagccaccca tttcttggct
    23461 gcggcttctg gtgtcatgcc ctgattgatg tcaagcataa cagcctccat atcctctttt
    23521 tcccaatgga agtgatcaac aatcctatga acagctggca ggtcggcctt taagccccga
    23581 cgtgcaatgg tattgatatt ttcctttgag ccaaaggttt tctttggatc tgccaggtat
    23641 ttcaaatcgt acttagcaaa catccaatga ggagaccaag ccgtcacaac gatcggctcc
    23701 tttttcttga ccgcctgatc aagtgaggtg gtcatagcac ctgtcgaagc agcaacgagc
    23761 tcccaatctg ccaagttgga ataggccttt tgcgtcttat cagcagcagt cataatacca
    23821 gctcccggtt caatcccaat aatctgttga ttggcttgat ccgaaagctc ctctatgctg
    23881 ttcacatcgc tcatataggc tggcacagcg agtcctagct ttgttccctt cagattagga
    23941 ccaagattat ccagcttatc ctgatacttt tggtactgct gctgatgggt cactggtaac
    24001 caggcacttg ttgaaaagtc tgcatcgcca tttgcgatgg tttgccacat cacagcatta
    24061 tccagtggtg tcaaggttac ctgataaccc tcatctctta agacctgagc gataacatgg
    24121 gtagaagcca cctcagaatc ccactgcaca taagcaatgg tcaccttctg ccccttgtct
    24181 gctgagcttg ataacatcgc agcaaagcca cgccccaaag ctgacaacaa aaagacagct
    24241 aaagcagcta gaccaagcca tttcttggtt tttccagtct gcgttctttc ttgcggctta
    24301 ccgttaaaat gctgagtcat acgatccaaa ataatcgcca agataacaag ggccaaacca
    24361 ctaacaaagc cacgcccaat atcagcatgc tgcaaggccg ataggacctc acgtccaaga
    24421 cctggagcac caatcattga gcctgtcaca accattgata gggccaacat catggtctga
    24481 ttaacacctg ccatcatcgt atgctttgcc aagggtaatt cgaccttcag taatttttgt
    24541 ttaggggttg acccaaaggc atctgaagct tcaaccaatt ctgtcggaat atgacgaagc
    24601 gctaaattgg taaaacgaac agtcggcggc aaggcaaaga taaccgacgc aaagacgcca
    24661 gggaccatac caatgccaaa aaaggcgaca gccggaatca aataaacaaa ggctggcatg
    24721 gtctgcataa ggtccagcat tggattaatc acctggtgaa caatcttatt tttagccatc
    24781 caaatgccca agggaatacc aagcaagaca gagatgaggc ttgctaccaa aaccagcgta
    24841 aaggtattga tcagctctgc ccacaggcct tggttataga caaataacag gcccaggagg
    24901 gtaaagatcg gcaaaggcca tttttttctt gccaagaaaa acatcgcaca ggtaaccaat
    24961 agcataaaca gtaacggatt gataaacaaa agggtctgcg tgatccaatc catcaaagca
    25021 ttgcccacaa gctgcagcag atcaaagaag cctgaaaagg tttttgtcag ccactcagtt
    25081 agttgctcaa ccagctgtgc cactggtaga gttgtttgta ataggttttc caaaatacag
    25141 tctctccatt ctaattaagg tcgtcatctg gaatattagc caaggcttca aggacacgcc
    25201 cacgaataat aacccctaac aagcggtgct gctcatctgt cactgcaatt ggcgcagaag
    25261 agtcataaat caagggcaaa atatccgtaa taacagtatc ctttgagacc gttctgacat
    25321 tacgatcaat aacctctgac aaggggagct ttttctgacg tgcttcaatc gctccgtctg
    25381 ctgttaggct tcctattagc tgacgacgac gattggttgc catgagcata gacacctcct
    25441 cattgtgcat acgattcaaa gccacctgcg gaccgtccag atcaaccgtt gttgtgatag
    25501 gcttaatcat aatatgctga gcagtcagca cctttgagcg gtcaacgtcc tctacaaatt
    25561 cacgaacaaa atcattagcc ggattggtta gaatatcctc acccgtccca atctgcatga
    25621 tctgaccgtc cttcatcaag gcaatacgat caccaatacg cagagcctca ttcaagtcgt
    25681 gactgataaa aataatggtc tgcttcatcg tctcctgtaa ttctagcagc tcatcttgca
    25741 tgtcacgacg aatcaaggga tctaaggcag aaaaagcctc gtccatcagc aaaatcttag
    25801 ggctgtttgc caaggcacgc gccaagccaa cacgctgctg catgccacca gacaattgat
    25861 cagggtattg gtccctgacc tcaagaagcc ctgactgatc aagcgcacgc tttgcaatct
    25921 ctcgacgctc ctgctttggt accccacgca gctccaagcc aaactctgtg ttttccaaaa
    25981 tcgtcttgtg tggaaaaaga gcaaagcttt gaaaaaccat attcatatca tgcctgcgaa
    26041 cttctctgag ctgatccaca gacagtttag aaatatccct tccctctaat aaaatagagc
    26101 ctgctgaggg ctcaattaat cgattaagca tacgaacaag cgttgatttg ccgctgcctg
    26161 aaaggcccat gatcacaaaa atctcgcctt cctgaacctc aaagctggca tcatagaccc
    26221 cgacagtaac tcctgtcttt ttaaaaatag cgctcttact tttaccagcc ttgatcattt
    26281 caagagctgc tttttgtttt ttgccaaaca atttactcaa atgcctgacc tctaaaatag
    26341 ttcccattct tttcctctct tgttctcttc ctcgattaaa gctaaattag cttaatagat
    26401 ttctaaaagt gccaccacaa ttttaaaata atgaggtcac tttttgctta aaaaaaagag
    26461 tctgcctaaa cagaacacat taattatata atatatggtc actttttgtc aagctggacg
    26521 cttgctaccc aagtatcagg atcgtcctaa gcagtgatat cactagtcaa ccaagcactt
    26581 aacagccctg aacagaccac agcaagcagg cctttctgac acttagcgcc ttgagagctt
    26641 acccagcagc ctcctctagc tgacttgatt gacctatctg actcttgtcc tgcaaccaaa
    26701 ccaatgctta gactgccaag caagctccca atagcaataa gatctgctaa gcaaagcgtt
    26761 agcttgcttt gaccatagct gctagtcatg tctaatagca ctctagataa atcaaaagcc
    26821 ccacctagca aggctagatg aggcaaaata ggtttagaga agggctttaa actgaatatt
    26881 tgagtcttcc aagaagcagt cgtcaaagcc acgtgggtga tgatactcga tgcgatcctg
    26941 atcctgtgga taggtgtatt tgccaccaac ctcccaaatg aatggatgga attggtattg
    27001 caagcgctcc ttacgcatct tccaaagctc taggatttca tcagttgagg ccatgaagtt
    27061 tgaccagata tcatagtgaa ccggaatgac aaccttggcg cggagatttt ctgccatacg
    27121 aagtaggtca acagaggtca tcttatcctg aataccgatt ggattttcac cataattgtt
    27181 caagacaaca tcaatatcgt agtcacgtcc atgcttagca aaatagtttg agaagtggga
    27241 gtctgcacca tgatagatgg ttcctcctgg tgtttcaaaa atgtagttaa cggttttgcg
    27301 agctaactct tcgtcagtca ctggaagtcc tgctagctcg ccaccatttt cctcagcgcc
    27361 agcaactggt aaggtaacga tacaggtacg gtcaaaggat tcaacagcag taaccttgat
    27421 atccttgaat gcaaagctat cgcctggttt taccacgatg atacgatcct ttggaacacc
    27481 ccagctctcc caaatcttgc cgcactcata agggccaaca aatttgacat ggtcaagctt
    27541 tggattgttg ataatggctg ctgcagtatt gatatcaatg tggtcactat gataatgaga
    27601 caccaagtaa tagtctaact cattaatcat aaagggatca ataaccattg gctgagctct
    27661 tagatttggt tgtagcttgc gaacccctgc catattggcc atttggtgac cacgaaccat
    27721 gtcttttact tttttagttg cctttccacg attggaccat aggtccatga caacattggc
    27781 accacccggt gttttgatcc agataccgca gttacctagc caccacatag agaaatttcc
    27841 ttcaggcact acctcttctt caatttcttc gtttagccag gttccccatt ctgggaaggt
    27901 gctaagaatc catgattcac gagttatatc ttgtacttta gccattatgt ttcctccaaa
    27961 atgaattttt atctatactc taagtataga ccttctttat tctcataaaa agaccaagtg
    28021 tcacacactc ttgtgttcaa aactggactg aattttggct caaaataaac taaaagcccc
    28081 agccttctcc taaaccaata gacagctgag gggtccttat caataggcaa gctagtagct
    28141 tacaataatt cgtgatgaat gagcttttca atttttgttt tcaaggcata gcggtcagca
    28201 tcgtccttaa caatggtctc gatcgccttt tctagctcaa gggaaaaacg agagctatca
    28261 ctcaagcgcc cctgctttga aaaacggatc aatctaataa tgtcatcatc gctcaaaata
    28321 ggattgacaa tcagtacggg aacaagagcc tccagtgcgt ctgttgttga taccacaatg
    28381 tcaacagaca tcaaatcaaa gacactctgg tattgctctg ttgtaaagac agcctcgatt
    28441 tgacaattgg gcaaataacg ctggcactgc ttcaacagca gcttttgaat cccaatgcca
    28501 tcatctgaaa cgataacaag cttggtcttg tcccagtcag catgactatg gcgcagctct
    28561 cctcccagat gaatcgttag ataagccacg tcatcatctg ttagacggat ctgccaagcc
    28621 tgctctagga ttacagcaca ggattgagcc atagcaaaga gctcctcgta tttttcctta
    28681 atatggtctg ttaaaggatt gatcgaaaaa atcccatagg cctttcgata aacaagggcc
    28741 ttgcaatgcc tggtcagctg tctaagcaag tcctttttgt gggtaaaatg cagctgatag
    28801 cgcagctcca gctgatcgat aaaatcacca atagtggctc gcatctgctc ataatcctga
    28861 ctttcaacat ggtgatcctg atcttttcta aaggatagca tcagcatggc tatcatgcct
    28921 acctcaatgt catctaaatg cagcttgaaa ttgtggtaaa gctcactagc caatgcctta
    28981 gcaatctggt attccttgcg cttccaaatc aggttaaaat cccttttaag cgctgtttta
    29041 gtttccgaat gcaattgcat gttgcgatag ctaagcagga taaaaggaag aatttgcagc
    29101 ataaactgac tatcctgaat attaattgtt ttgcctaggc tagcctgaga caaaaagagg
    29161 tattcgtgaa aataatccaa aacctccttt gaaaaataag ctgacaagcc ttgtgtctca
    29221 gaaagcttat gatcaaaaag ctcaataaag ctgctattgc ctccctgata aacacctgcc
    29281 aataccttgt aaaggtactg aatcaaagcc atagggtgac agtcaaagta atagcccttg
    29341 gccttggtgg catgcagctg aatcttattg ttatagctag acaattcctc tctcagttca
    29401 gcaaggtcat ttaagatggt atttctggaa acatcattaa tcatcatgag cttatccagt
    29461 gtcacccgct ctgttgccac tgcaatataa atcgctgata agctcctgcg ctcatcaccc
    29521 ttcatgacat agtgataatc tgccacttca ttgaggagct gttggcaggc agccttttgc
    29581 tcactattta gcaagatgcc aacccgagga taggagacaa tttgagcaac atggctgggc
    29641 agcgcttcgt taattttatc caaatgataa tagattttgc gccgcgactg acccaaggca
    29701 gctgaaatcg ccatgactgt ctcagcctcc ttcaatcgaa tcagatatga cagcagatca
    29761 tagctttttt tatccaaaat aatcacgttc atacctccct tctataaaac atcactacca
    29821 cacagcctta tcagtttacc attttaccta tctgtaggaa agaatactag gccaaagtca
    29881 atttctaaat aggaaaaaac gaacgatcat tagttttctg aagataaaat tcctaattag
    29941 ttcgcttttt tcttttataa ttgtaatagt tgaattaatt attaaacttt gtctaaaata
    30001 agaggctttt tatcccagat tgcaacaagg gttaacacct tgaccttaag cctagctaag
    30061 cagctctcac taagttacta gctgctgcct taatgccggc tacctttttg gccataatag
    30121 gcatttggac catgctttct aaggtaatgc ttgtccataa tataggttgg agctggctcc
    30181 acacgaggat tgatttgttc tgtcaggcgg ttcatcttgg ccacctcttc gagcaccact
    30241 gagtgataaa ccgctaattc aggcgtcttg ccccaagtaa agggaccatg attgcgaaca
    30301 acaataccag gcactgccat cggatcaaga ccacgactag caaattcctc taaaataacc
    30361 gtacccgttt ctttttcata ggctccatta acctcatcgg cagttagaga gcgagcacat
    30421 ggaatggggc cataaaagta atcagcatga gttgtcccat aaaatggaat atctcgccca
    30481 gcctgtgccc agccaaccgc ttctgttgag tgtgtgtgca caatcccgcc aacctctggc
    30541 catgccttgt ataattgcac atgggttggc aaatcagaag aagggttcag ctctccctca
    30601 acaatagtgc catctaagtc tgtaacgacc atattttccg gtgttaattg gtcatagtca
    30661 acgccgcttg gcttgatgac gatacgtccc agctcacgac agacctctga gacattgccc
    30721 caggtaaatt tcaccagccc atgcagcggt agggccttgt tggctgcaca gacacgttca
    30781 cgcatttctt gtagcctttt tgccattagc ttaaccccgc tttctcaatc agtggataaa
    30841 ggaaatcctg tgcctccttg atggcagctc ttgtctcctc tacagtttca cagttttctg
    30901 accacatttc aatcaaaaat ggaccatgat aatgcgtttt cttgagcaca tcaaacattg
    30961 cttcccaatc aacacagcct tgaccgaatg gcacatcacg aaattgccct ttagatgttt
    31021 ctgtcacagc ataggtgtcc tttagatgca aggcagcaat agaccgatgc ccattgtaaa
    31081 attcactcca gaggtcatta tgccaagcag agacattgcc cgtatctgga tagacaaaga
    31141 gataagggga gtcaatttct ttttccacag ctaggtattt ctcaattgag ttgataaaag
    31201 gatcgtccat tatttcaatg gctaaaataa cctgagcttc ctctgcccaa gtgcaggcct
    31261 gtctgagatt tttgataaag cgcgcacgcg tttcaggtga tttttcttca taataaacgt
    31321 catagccagc caattgaatg gtacgcacac caagatcctg tgctagcaca atgcattttt
    31381 tcattagctc taatgatgtc gcttctgttt ctggattgct agagccaagt ggataacgac
    31441 gatgaccaga gaagcaaatg cttgggatac gaacccctgt ttcataaata gccttgacaa
    31501 tgtctagtcg ctcctgttta ctccaatcca agcgcgctag gcgagcatct gattcatcga
    31561 cagacatttc tacaaaatca aagcctaata cctttgcaaa ttgcaagcgt tccagccaag
    31621 taaaatgctt tggcgttgct ttttcatata taccaatagg acgcgccata ttgttacccc
    31681 caaatgcgtc gaatctcgtc tttaaaggca cgtgccgctg ctgcaggatc ctctgcttca
    31741 gtgataccac gacctgcaat aaaggtaaag acattaaccc cttcaaagag cttgagggta
    31801 ttgatatcta agccacccgt caccgataca cgaaagccca tgtcaatgag ggctttgacc
    31861 ttgttcagat ctttttcacc ccatacttca ccagcgagta gggcgtcacg tgattgatgg
    31921 taaatcgcct gtgaaatgcc tgcatctagc cacaattgtg cctgttcata ggtccaatca
    31981 ccatacagct caacctgaat ctcgccacgt tccccacgct cttctttgat ggctttcagt
    32041 gcggctgcca tggttggaat agtggcacag caaatacaag tcatccagtc cgcaccacgc
    32101 ttagcattat tcttagcaac agtaccgcca gcgtctgcac acttggtgtc tgctacgatg
    32161 atcttctctg gaaataagct acgcagcacc tcaaccaatt cgctgcctac ttgaagcagg
    32221 caaactgtcc ctgcttcgat tacatcaacc tcgtgaccaa ctgcaacagc agccctgacc
    32281 gccccctgca aatcagaatg atctaaggca acctgtaatt ttggaatatg tgtcatgatt
    32341 ttctaccaag agcccgtagc accgccttca atgcttaata gcgagctcct atcctttctg
    32401 ttgtgtttga ttcgtttagt gatgatggct tgtctaagaa tccaaatcca agccctctaa
    32461 ataaggacta tttttggact cgtccaccaa agccaaaacc tctgctggag tgtgacaggc
    32521 aactaagcgc gaaatagcgt cttccagttc aaaaagggcg acaatctgtg gaatagcaac
    32581 tgttgtatga atagaaggat cagttgccgc caaggttagc aataccgaag cctctttgcc
    32641 atctgaaaag gtcaccggct tggtcagtgt gataagagca aaggcatttc gcttgacccc
    32701 tacaccagcc tctgcgtgtg gcatggccat tcccggcata aggacataat agggcccgta
    32761 cttttctgtt gatgcgataa tagcgtcata atattcagag gtcaccgccc cgctgtcaat
    32821 caaaggctga acagctagct taaccgcttc ctgccagcta gctgctgaca agcccaagcg
    32881 aatagagttg ttttcgataa atgctttttt taaattcata taactatcct ttctaaatca
    32941 aattctttgg ccagacactt tttgcctcac tcctatctag ctgataaaga gaaagagctg
    33001 gaatctctct tcacaactct cactccatct atccttactg aaagttgatt gctacagctt
    33061 agcttacagc caagtggctg ctcttaggct cactatcatt tgccatgagc agcactgatg
    33121 tcatcagggc cgctctaaag caccgcctgt agcttggttt tgatttcatt gtcgtccata
    33181 agattatcta gtccaaccaa atgacccttt gtacgcccat ctaattcatg aatcaggtga
    33241 ttagaagcaa ccacaatatc atagcctgag gcaagtccct ttgcctcacc cactgagcaa
    33301 gaagcagact gaatatcagt caccccaagc tgacgaagtg cgttttcaac cttcatttta
    33361 ataaccattg atgaccccat gccattaccg catgctgtaa gaaccttaac catttatttt
    33421 cctccgaata tatgataatt tgatatgaat gaagacctgc agaagtatat cgacaaactc
    33481 ctaccagcct gtgctaaaag acgaataagc agctattatc accttgctta ttgtgcttca
    33541 ccgcggtagt aagcctcttt atccttagcc ctagcaaatt gtagctgtgg aatagcaagt
    33601 aagaagacac acaccaccac atagcctgca ataccaagga acttgaagag ataaccaaat
    33661 ggaagccaag gaagcaccag gtcaatattg ccatgataac cacctgtcaa gcccaacaga
    33721 ccaactgcca ctgcacctaa ggcaacctga agaatacctg atataaagga tagagcaaca
    33781 gctgccttcc agccaccacg cttatctgca taaacagcaa tcgcagcatt atcaaagaag
    33841 accggaacaa atcctgtgat gatcaagatt ggatttttaa agatcacaag aagtgcaata
    33901 gtgattagct gaccgataag cccaaaggta aatcctgaca aaacagcgtt tgaagagcca
    33961 aagccatatg acgctgcaac gtccaccgca ggaaatgaac ccggaaggag cttacttgaa
    34021 atcccttgga aggcattggt caactctgac acaaacatac gcacaccctg catcaggata
    34081 aagagataaa ctgagaaagt taaggaggtt tgcaaaatat acataaagaa ggcctgctta
    34141 gctggattaa aggcaccagc acctataagt tctgcattag acatcatatc tgggccaagc
    34201 acagccaaga tagcaccaaa gaaaaccagc attagagtgg cagaagcaac caccgtatca
    34261 tgaaaaatcg ttaaaaagct tgctagctta agattgtcaa ggttctcttc ttttttacca
    34321 aagaaaggcg ccaccttgtc aacaaaccag atcgcaaact gctgctggtg cccaatggca
    34381 aagcctccac cacctgtcaa gcgctgagtc gcctcaactg tcatattgga gctgacagcc
    34441 cagtaaaggc cacagataat accgaccgcc caagcaccaa aagcattttg aagctgaggg
    34501 attaaaagaa gaacaaacac agagatggtt gccgcctgct gcaccatgat atgacccgta
    34561 ataaagagcg tacgaacctt tgtcacctta cgaagcgcca ctagcaaaat attgacccca
    34621 aaaccgatca aaagggctgt ggtggcaacg ctgatggatc ccatctcctc tagcttggta
    34681 ttggctgctg caagtccaaa gtaagggtca ataactgcgg cctttaattc aaatttctta
    34741 cccaatgcca ctaggattgg gcgaaaggtg ttaaccaagc ccccagcacc aacattcaaa
    34801 atcagataac caaccgttgc cttaacaaag ccagcaaata cttcatgcag gggcttttta
    34861 agcagcaaat acccaatcaa aaccaaaaga cctacaaaga aagccggatt ttgcaaaata
    34921 tcttgcgaaa accagtttag gggagctata agcattttca taagaactac ctcttttcac
    34981 agttaataaa tatgatattt tctatacaat aattgtaaac gatgtaagcg tttaaaaaaa
    35041 agaccaacaa tcacacaaag aagtgttcaa aaatgtactg aagccaattt ccagctagct
    35101 ctgatcactg ttaaagcact atcattaatc tctaattaat aaccaaacac atcacaacaa
    35161 tatcgggcta acacaaaaat aggccagccc atactgccca gccaaaacga aacaagcaat
    35221 caattcaagg cacttaaccc tgttttatat cgtacaaagc ccttttaaga tgattttgtt
    35281 tgtttcctaa tcgtaaatta gttatctgat ccgttctctc ctcagatata ctcaccctta
    35341 tctaattcta ctgtcaaata gctacttact cataagcaaa tgaatattaa gcaaccacca
    35401 agctacaata aaagacctta ccctgttggc aagatcttat tcattataca atttttcctt
    35461 ctgcgacatg gactacctca tcacacaagt cttcaatatc tgtcttcaga tgtgagctta
    35521 aaatcacaag cccatttttg ctaacatcta aaagcaattt tttcgtttgc tccacgctcc
    35581 tgtcatctaa tgcattcatt ggctcatcta atataaggat cttagggtga tgcatcaagg
    35641 cctgaattaa ccctaatttt ttcttagtgc ctagcgatta atgcttaaat gctgtttgac
    35701 taaactgatg taaatgataa acatctaacc aaaaagctaa atcaatatct ctagccttag
    35761 gagagattga cctaagcaac tctagatttt gtaacaatgt taaatgtgca ataaactctg
    35821 gattctcaat caaaatccca gcatcctcga tataattatg gtactgtcta atttttttat
    35881 tgtcctgata aacagctcct tcatctaatt tgatataacc agctaaggcc ttaagtatca
    35941 aggtttttcc cgaaccatta atacctacca aaccatagat attaccttct ttaaaagtaa
    36001 gattaatatc atctagaaca aggttaccct tatacagttt tctaccatgt tcaatccgta
    36061 acatctcagc tctccttata ataattgtca taaagcatat gtaccaatac tattagcagc
    36121 aggcaccacc aaacatcaaa caaaaagtaa cgtatcaagg tgagactagc aaacaagatc
    36181 atagctacta cagcagatga ggcatagcgt atcataacat aaatcaagca aatatctata
    36241 gtaagccaag ataccataag ataacatagt cgttcaatat gatatggtgc accataatag
    36301 gtcatcaata cacctaatat taaaacgata aaaagtaacc actctttaat atagaaaatc
    36361 gtactcgtcc gccatagctt gttaaaaaat accaactgac ttcgagcatg aaaacgaaag
    36421 atttccttag ttccttcagc caaatccgcc aaaaatgaaa tcgtaaaata aaagctgttg
    36481 aaggacaagc ctagcaaggt gataaccttg acaaaatcag ctgtctcccc ttcaatcact
    36541 ggaaacggca ttagcaaccg atagcacact aaattatgaa aatctcgctc cccagtcata
    36601 ttagccttaa tcaataaaag atgtattagt aagccagtaa gacatgcttt cattccaaca
    36661 accagcaggt tagataattt catggtgctt cctcaatttt aaaacgatgc acacacccac
    36721 taagcctaaa taaggtgata aaaggtaagg aatatcagca tcactataag atgttgacat
    36781 caaagaagtc ataagaacat atttgggagg taaatagcta tataacaacg gtgacaaagc
    36841 ccacatcaaa atcaaataga gcatgcttga cttaataaag gattgaagat agtcaacaag
    36901 aaaacaaacg aaatacgtat gaacgaacaa agctaacgat tttactaagc aatagtaagc
    36961 tataaaggtt gttgctcctt gaccaaaaaa acgcaatatt gagttttgat caaaataagg
    37021 cattaaatta ccgttcatat gggcaacacc atttagccaa gacactaaag tcaaagcaaa
    37081 tattacaatg taaaaactca gtaaaacata taagctcaac tgaagcttta aaaaaataca
    37141 ccttttacca tagtcagact ttctgccaat gaggtattta agatgtcttg acttaaggta
    37201 atagtaggca taggccacta aaatcatcac tagtggatag ataaaagatt gataaaaact
    37261 aaaatcaaac accacactat ccaaacgtat catactcaac aatagacttt tctttacctc
    37321 aattccacca gataaatcta ctgcacttgt atcaaaaaat aagatatgct tcaaactgtc
    37381 aaaataaata aaacctaaaa atagtaacgg gactaatgga taaaaatagc gaaatggaaa
    37441 taatctatac tgtagcattt atgaataact cccctacaaa aaatcaagga aacgcctcgt
    37501 tactaactca attcacaatt gtagatattt accaattgtc tggagaccaa ctaccactaa
    37561 tggttgttgc tccgtcccac caattttcac gtaccagatg caaggcataa aggtacccac
    37621 ttttagtatc ctgtgtataa attcctctgt cgcctgtcca agttttatct atatcacttc
    37681 ttctttgacc gttactatta gctagatagt gccttaccac aatttctcta ttacgtcctc
    37741 ttgaatctaa attaacgaca taataaggcg ccgcactctt cacaagataa tctttcgtcc
    37801 ttccaaaaga tgacgtgatt ctaaaatttt gcaagtaacc aatttgtcgt tctgctataa
    37861 ctaaagaact aatcaataat gtagaagcta caattgccaa taatccaatc ttaattttgc
    37921 ctaattttat tttttaataa tttataattt ttatatattt agcacatcat cagcgcttcc
    37981 ttgacaattg ataatacaat tcatgctagg cttaatcgat aaaactaaat actagatagt
    38041 aatc
//
LOCUS       DARYLJ010000019        36829 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYLJ010000019 DARYLJ010000000
VERSION     DARYLJ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36829
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(37..1368)
                     /locus_tag="TU746_000836"
     CDS             complement(37..1368)
                     /locus_tag="TU746_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL0891199.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1459..2238)
                     /locus_tag="TU746_000837"
     CDS             complement(1459..2238)
                     /locus_tag="TU746_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL0891200.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2269..2913)
                     /locus_tag="TU746_000838"
     CDS             complement(2269..2913)
                     /locus_tag="TU746_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL0891201.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2919..3569)
                     /locus_tag="TU746_000839"
     CDS             complement(2919..3569)
                     /locus_tag="TU746_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL0891202.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3584..4774)
                     /locus_tag="TU746_000840"
     CDS             complement(3584..4774)
                     /locus_tag="TU746_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL0891203.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4966..5868
                     /locus_tag="TU746_000841"
     CDS             4966..5868
                     /locus_tag="TU746_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0891204.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(6765..7907)
                     /locus_tag="TU746_000842"
     CDS             complement(6765..7907)
                     /locus_tag="TU746_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891205.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(7904..8767)
                     /locus_tag="TU746_000843"
     CDS             complement(7904..8767)
                     /locus_tag="TU746_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891206.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(8778..9104)
                     /locus_tag="TU746_000844"
     CDS             complement(8778..9104)
                     /locus_tag="TU746_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL0891207.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(9708..9872)
                     /locus_tag="TU746_000845"
     CDS             complement(9708..9872)
                     /locus_tag="TU746_000845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891208.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(10111..11007)
                     /gene="era"
                     /locus_tag="TU746_000846"
     CDS             complement(10111..11007)
                     /gene="era"
                     /locus_tag="TU746_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL0891209.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGAFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(11143..11544)
                     /locus_tag="TU746_000847"
     CDS             complement(11143..11544)
                     /locus_tag="TU746_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL0891210.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TU746_000848"
     CDS             complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TU746_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL0891211.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(12371..12997)
                     /locus_tag="TU746_000849"
     CDS             complement(12371..12997)
                     /locus_tag="TU746_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0891212.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(13052..13627)
                     /locus_tag="TU746_000850"
     CDS             complement(13052..13627)
                     /locus_tag="TU746_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL0891213.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQVPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(13674..14774)
                     /locus_tag="TU746_000851"
     CDS             complement(13674..14774)
                     /locus_tag="TU746_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL0891214.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(14877..15092)
                     /locus_tag="TU746_000852"
     CDS             complement(14877..15092)
                     /locus_tag="TU746_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL0891215.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TU746_000853"
     CDS             complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TU746_000853"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL0891216.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TU746_000854"
     CDS             complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TU746_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL0891217.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TU746_000855"
     CDS             complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TU746_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL0891218.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(17521..18249)
                     /locus_tag="TU746_000856"
     CDS             complement(17521..18249)
                     /locus_tag="TU746_000856"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL0891219.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(18549..19229)
                     /locus_tag="TU746_000857"
     CDS             complement(18549..19229)
                     /locus_tag="TU746_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891220.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(19216..20004)
                     /locus_tag="TU746_000858"
     CDS             complement(19216..20004)
                     /locus_tag="TU746_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891221.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(19992..20798)
                     /locus_tag="TU746_000859"
     CDS             complement(19992..20798)
                     /locus_tag="TU746_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891222.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(20783..21724)
                     /locus_tag="TU746_000860"
     CDS             complement(20783..21724)
                     /locus_tag="TU746_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891223.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(21802..23424)
                     /gene="nikA"
                     /locus_tag="TU746_000861"
     CDS             complement(21802..23424)
                     /gene="nikA"
                     /locus_tag="TU746_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL0891224.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            23926..25566
                     /locus_tag="TU746_000862"
     CDS             23926..25566
                     /locus_tag="TU746_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0891225.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGEKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(25810..26499)
                     /gene="rplA"
                     /locus_tag="TU746_000863"
     CDS             complement(25810..26499)
                     /gene="rplA"
                     /locus_tag="TU746_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL0891226.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(26605..27030)
                     /gene="rplK"
                     /locus_tag="TU746_000864"
     CDS             complement(26605..27030)
                     /gene="rplK"
                     /locus_tag="TU746_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL0891227.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            27266..28063
                     /locus_tag="TU746_000865"
     CDS             27266..28063
                     /locus_tag="TU746_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0891228.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            28218..28568
                     /locus_tag="TU746_000866"
     CDS             28218..28568
                     /locus_tag="TU746_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL0891229.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(28897..29352)
                     /locus_tag="TU746_000867"
     CDS             complement(28897..29352)
                     /locus_tag="TU746_000867"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891230.1"
                     /translation="MTISDQKVNASQYRWRQYYYRMSPTERELKKEKEVLRNFIATIK
                     LSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKISNKVEIVSSLIDEHFPEGH
                     SRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIMTRKKLWYIQ"
     gene            complement(29727..32126)
                     /locus_tag="TU746_000868"
     CDS             complement(29727..32126)
                     /locus_tag="TU746_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL0891231.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
     gene            32246..32419
                     /locus_tag="TU746_000869"
     CDS             32246..32419
                     /locus_tag="TU746_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891232.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            32506..33312
                     /locus_tag="TU746_000870"
     CDS             32506..33312
                     /locus_tag="TU746_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL0891233.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(33468..34301)
                     /locus_tag="TU746_000871"
     CDS             complement(33468..34301)
                     /locus_tag="TU746_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL0891234.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(34302..35027)
                     /locus_tag="TU746_000872"
     CDS             complement(34302..35027)
                     /locus_tag="TU746_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL0891235.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            complement(35087..36019)
                     /locus_tag="TU746_000873"
     CDS             complement(35087..36019)
                     /locus_tag="TU746_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL0891236.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            36165..36812
                     /locus_tag="TU746_000874"
     CDS             36165..36812
                     /locus_tag="TU746_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL0891237.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
BASE COUNT        11395 a         8451 c         6633 g        10350 t
ORIGIN      
        1 taatagacca atggttttcc attgatctac tgtgtattaa aaaaacaggc tagttaacat
       61 aataatgctc tcggccacca acgtaccacc aaaaactgta ataaaggttt gtttaaagcc
      121 atttttatgg ctgagaccag taaggctcaa gaaggttaaa aagacgccag actggggtac
      181 aatggtcaaa atattagagg caacagctgc cacacgatga atgatctcag gtgaaacgcc
      241 tgcatctaaa taatattgag caaaatttgg cattacgatc cctaacgctc ctgaagacga
      301 acctgtaata gctgccatag ccgaagtcag gacagtcaag ctgatcacag gtggcccagg
      361 aatattcaaa atgatgtctg agaatacgcc aaaaccagat gctgctgtaa caacagaacc
      421 aaaggctact gcagaggctg tcgcaaagat tggaccaacc gcaccgctag caccaatgct
      481 gagggtcgca attttcttat caatgtactt gttaaataaa acgatagctg aaataattcc
      541 tgtcaagagg gccacataaa tgatattttt cttaacgaat tcgtccccta gcagactacc
      601 tatgatggca ataacaatca agagtatcaa aggcaagatg ctgactacaa atggtggtaa
      661 aaccctttca gttgtatctt catttgtttg actagtatag gtcgcatagt tttcgccaac
      721 ttctaaactc ttagtcaaac aacgcttcat atagaaaaga ccaaaggcga tacagccaac
      781 actccctaaa atacttggca ccaaggctgc ggttagagac gtgttaagat attgtatagg
      841 gataacgttt tgaatcgctg gtgtaccagg taagatcgtc atagtaaagg ttgcaatccc
      901 caaccaaagt ggtacttgaa ttaagttcca tgctaagtcc atctttttaa agagagagcg
      961 tgccaagggt agaacagcaa acatgaccac aaagagacta ataccaccat aagtcaaaat
     1021 agcactgatg ataaaaatag ccaccaagat acggtaaggg ttttgataac ctactttttt
     1081 caagataaat tcagcaatgg aaactgttgc accactgact tccatcaatt tagctaaaat
     1141 agaccccaac aagaagatag caaagtagct catgatatag ccacccagcg cacccatata
     1201 gttatttggt tccttaccca agagtgactc aactagtggc atactattta gaaggacgac
     1261 caaaatcgtt gccataggag ccgcaatggt aatatgaatt tcctttagag aaaaataaac
     1321 gatggcaata atgcccagca agaccccaat tggtcctaaa aattccatag tgtttctcct
     1381 ctcacattca gaaggagcaa gagatagaga aatgtcactc tatctccaat cctcttattt
     1441 acactgaacg gacagctctt actgagcagt gtagccacca tccaagataa ccggttgtcc
     1501 agtaattccc tttgccttat cacttgctag gaaggagaca taatctgcaa tttcttgtac
     1561 gtcaatcaaa cgtttttgcg gtaccaacgg gtacaacact tcttccaata cattttcaag
     1621 cggaatctta cgtgtcttag agaggtcttc aaattggcca cgaacgagtg gtgtgtccac
     1681 atagcctgga cagatagcgt tgactgtgat acctaattct gcggcttcaa gcgctgcaac
     1741 ctttgtcaag ccaatcaaac cgtgttttgc tgaattgtaa gccgcttttc cggcaaaacc
     1801 aatgacacca ttgatagaag ccatattaat gacacgacca aagccttgct ttttcatagt
     1861 tggaaaagcg cgcttaatag cgataaatgg cgctgtcaac atgaccttca acataaattc
     1921 atattttgct gttggaaaat cttcaatcat ggcaacatgc tgcaaacctg cgttgttgac
     1981 caaaatatcc aaacgaccat gcttttcaac tgtataatca atcgctttat tgatcgcttc
     2041 ttcatttgtc acatcacaca aaacagaatc agccgcccag ccttttgtgg tatactcatc
     2101 aacaacagca tctaattttt cttgattgat atctgaaaag acaacgattt tgccctcttt
     2161 taagaatgtt tcaccaattt gtttaccaat accgcttgct gcacctgtta cgaatactac
     2221 ttgtttagac atatttattt cctcactttt tttaaatatt gttttctatc agttatgata
     2281 aattaatctt gcttcggtgg cttcttgaac ttcttcaaag gtataatctg gatgaatttc
     2341 ttctactgcg attccctctg gagtgactgt gaagacaccc atttctgtga caatcttgtc
     2401 aacaactcct gctgctgtca atggcaatga acactccttc aagattttcc atttgccttt
     2461 attggtatgc tccatagcaa caatgacttt tttagcaccg actagtaaat ccatggcacc
     2521 gcccattcct ggaaccattt tccctggaat aagatagttt gcgatgtttc ctttttcatc
     2581 aatttgcaaa gcgccaagaa ctgttgcatc gacgtggcca ccacgaatga tcccaaatga
     2641 agtggtgcta tcaaaaaatg ctccgcctgg tacgatgcca accggctgac cacctgcatt
     2701 aactatagtt ggatcaatgt catcgcctac tttatctaag ccgacaaaac cattctcaga
     2761 ctgcagcatg atagtcacac cttctggtaa aaatctagct accttggttg gcaagccaat
     2821 ccccaaattg accagggaat tatttggaag ctcgagtgcc acacgtttag caattcgttc
     2881 ttgaatttct tctttgctta attctttcac cataacgctc attctccttc cactagataa
     2941 ttgacaaata tgcctggtgt ttgaactgca atgggttcaa tgtctccaag cgagacaatt
     3001 tcacgcgctt caacgatggt cacttttgca tttgctgcca taacctggtt gaaattattt
     3061 tcagagccct tgtagcatag gtttcctaat tcatcagcct tatctgcaaa aattaaagcg
     3121 acgtcagctt tcaatggtaa ttctaacaga taatccttgt cattgacctg taatttttgc
     3181 ttaccttcct ctaccaaggt accgatgcct gtcggagtca agaagccacc cagtccgtaa
     3241 gctcctgctc ggattctttc agccaaggtt ccttgtggca ctaagtcaat cactgtttca
     3301 ccggctgtca tttggcggcc tgcttctttg ttcaagccaa tatgagaagc gataattttc
     3361 cgaaaccgat gttgtgctac cattttaccg acacccttgt ctgggaagcc tgcatcgtta
     3421 caaataagag ttaaatttgt aactcctttt gctaccaaag cgtcaatcag gcgctctgga
     3481 ctcccgttag tcataaaacc accaaccatg atggtgtcgc catcctttac aaggttaaca
     3541 gcttcttcta tgctaattcg tttattcatg aaaccatctc cttttatttt tcaatcaata
     3601 cagacgtccc ttgaccgcca ccgatacaga gtgttgccaa tcctttatgt gcctgacgct
     3661 tttccatctc gtgcaatagt gtgaccaaga tacgcgcacc gctagcaccg atcggatgac
     3721 caagagcaat agcaccacca ttgacattga cgatagccgc attaagacca agctcatcta
     3781 caacactgat agcttgtgag gcaaaggctt cattggcctc caccaaatcc aagtcttcaa
     3841 ttgtccaacc aaccttagca agggccttct gagtggaagg aattggccca gtacccatga
     3901 cctctggtgc tacaccagca cttgcataac ctttaatggc tcccagaatt ggaagaccaa
     3961 gttcttcagc tttgtcacga ctcatgagaa ggacagctgc cgcaccgtca ttaattcctg
     4021 aagcgtttcc tgcagtaaca gttcctgaac catctcggac aaaggccgga caaagggctg
     4081 ttaatttttc aagggttgtt ccagctttaa tgtactcatc ttctgccacc aaaattggat
     4141 cacctttacg ttgcggtact ggcactggaa taatctcatc tacaaagcga ccagcggcct
     4201 gcgcagcagc agctttttcc tgactagcca aagcaaatat atcttgagct ttacggctaa
     4261 tcccatagtt ttttgcgata ttttctgctg taattcccat gtggtaatca tgaaaggcat
     4321 ctgtcaaacc atcattgacc atagtatcaa tgatttttcc atcgcctaag cgaccacccc
     4381 aacggtaatc tttgagcaca tagctggctt ggctcatatt ttctgtccca cctgcaataa
     4441 tgatatctga atcaccacag acgatacttt gtgctgctaa ctcgatggat ttgagaccag
     4501 aaccacagac catatccaca gtgaaggcag gtttgtcgtt tggaatacct gcagttatcc
     4561 ctacctgtct agcaacattt tgaccgagtc ctgcatggag gacatttccg aaaatgacct
     4621 cgtcaatttg ttcaggcttc acacctgatt tctctagtaa tgcttctaca accacttttc
     4681 ctaattgaac agccgagaca gatttaaagg ctccaccaaa tgaaccaatg ggtgtcctaa
     4741 cagctgtagt gataacaact tctttaacca acatgcgatt ctccaatcta tttgttatag
     4801 aaagcgcttt ctgtttttgt gaatttattt tatcactact aaaagcgttt gcaaaattcg
     4861 atttttttat atgactataa aaaattttta ttatttttta ttgacagcta taaaaattat
     4921 tattagtatg aagaaaaaga catctgaaat gaaagaagag gcaatatgga tattaaacat
     4981 ttacgctttt tcattgctat tgtagaaaat aattttaacc tgagccgtac cgctcaacag
     5041 ctttatattt cccagcctac cctcagtatt atgattaatg attttgaaga aaagcagggc
     5101 attaagctct tcaataaaaa atacaataaa atcctcggct taaccatgac aggcaagcaa
     5161 ttttatgagg attctttgga ggttatccgc aaatatgaca agatgcacca aaatctcttt
     5221 tccaccaatc aaaagttgga cggtaatatc actatcggca ttcctccatt aattctgtca
     5281 attgtttttt caaaaatcat gccagaaatt attctagaaa atcccaatat ccactttaat
     5341 attaaggagt atggtgctaa tcggctacgt caggaattga ttttagagaa tgtggatatc
     5401 gccattcttc tgcatcctga acgaattgct gcaaacacca ttgattcttt ccaaatccaa
     5461 gaatctgagc tctgtgcatt tgtctccaag aaccaccatt tggccaataa aaaaatcctg
     5521 acttggatag aactccacaa tgaaaaacta gctatatttg ataaaacctt catgattcac
     5581 catctcatca aggaaaaatg taagtatact gacattaacc cccaaatcat tctggaatca
     5641 gcttcttggg actttctgat caattctact cgtatcaacc ctcaactaat gacgattatt
     5701 ccaaaaccaa cggtagatag ctatggtttt caggatattg tggctattcc tatggagaat
     5761 cctattcctt ggaaagtcat ggttagtcgt ctcaaaaaag atcattattc caccatagaa
     5821 gaatacattt tcaacaaaat gcttgaaaaa tttcatgtaa tcgaatagag actaacaagt
     5881 gatccctttc acatgactgc acgtgccctt cgacatatgg cacctcaact aacccttagc
     5941 gcatatggaa acagctcaat tctttttgaa ggataaaact aaagaggctt gacgatccat
     6001 actaactcag acccaatatt attatcaaga tcctaaatat taacacaact catttataac
     6061 aattaactta caaaaaatgg tctactcctt tgaggcgtga cagcaatact gcaatttata
     6121 aaaaatgact gtcaagacaa tatctctgaa ctcagtcact gtttctcaaa aatcactcac
     6181 atctaatgga gtactatcaa gaaaaagtta tttttaaaat catcaataac ctatctaaat
     6241 tttctaaaca atgccatata aaaagagctg gagtcaccaa gctctaattg atttttacat
     6301 gatgctctat aacaatatcg tttaaagatc attctttttt actagtatgt tgatcacatt
     6361 ttctaaaagc cagaaagaga cttgaatacc gagtcccttt tctttttatc tataaacagc
     6421 cttaaagaag cccagacagg ctgcggtaat tttcttaaca tgagcttcta ctatttctct
     6481 tgttaagccc tgctcacttg atgattcgtt atttttacca cctgaagact ctcctctaca
     6541 taggctactt tgtcatctag ttcctgcttc ttaacgatat atcatcgtct caattgatgc
     6601 cacttccctt atcatcttag aaaaaagcta atttctatac ctttaggtgt tctagatcac
     6661 aaaatagctt tctcaatcct atctaccttg caagaattca ttgaatgccc ttaacttttg
     6721 cagtaacgac aataaaaata gtttagataa cgatgctatt gatgttactg acttaccctc
     6781 tttattgata agtatgctaa atataagcaa agaaatgcaa aagctaatct aatcatgaca
     6841 ataactaatc catcaaccca aaaactgcca aaaaagccgt cataagcaag cttaagcatt
     6901 atgtttggtg tactcgcagt tgatacagat aaaatactca acaccttatg aggtattcct
     6961 gcttggaaaa tatccataag aaaacttggt acaaaaacac tagccgcaga caaggcaaaa
     7021 cctgtcaatg gagacttaac cttacttgaa ataaggatag tgatagccgt aatcaggata
     7081 agcccaataa actgataggt gactagattg ataaatgttc ccaaaagagt cattttttct
     7141 ggaaaagcca ttatattcac attgctgtta atccaataca gattgagttg aacactcgtg
     7201 tcccaaccac ttaatccaaa ataccaaaca aagaccgcta atattatggc gtaaaaagta
     7261 acaaacactg aggtgcttat caagtaacta cttattatct tggctatcgt aagtttatta
     7321 cgaccatacc tagttgtcaa taaaatagga ttcatatttt tagcagtatc accggaaaaa
     7381 acaggagcga tgaagtaaac agacaaaaga agaagaagga tataagcact atttatgacc
     7441 agaaaaagct gattccaggg tgcaaaatta cccaacttca gctctttaaa gggaagataa
     7501 gagccaagag ccgtttgaga ttttggggtg atcttactga aatcaatagt ctcttctttt
     7561 ttcaaattaa aataataatc tctaaatttt ggatcaaaat ggctagttac atagtagcca
     7621 tacacattga agacaggatt ttttgagctg ccacctagag tataatcttt gattgttcta
     7681 attaataact cattggacaa ttgaccggta tgttcttccg caaatcgctt gtttatctca
     7741 acagcatctc ttccatgaat tttatctatc gaagaaccac tgatttgtcc attaaaaaag
     7801 ttgatataaa ataacccaaa gattgctaat aagctaacaa taaacattcc caaaactgat
     7861 ttggttcgga tcagtttttt taattcaaat ggtaagagag ctttcataac acctgttcct
     7921 ctctaaagtg ataaatgtat aagtcttcta aggttggtga cactagttga gccaactgat
     7981 ttggtttctc atcactaacc acacgaaaaa cacgactaga tgaaactagt ttctcattga
     8041 ctacagcata ctgaccatgc cttggtaacg gcgaaccatc agagacagaa aactcccaga
     8101 ccttgccaaa gatggttttc aacaattctt gactactact cttatggata aattgaccat
     8161 tttttaaaat gataatctcc ttagcaatag cctcaacatc agagacaata tgagttgata
     8221 agataataat tttgttggcc gacaattcgc taataatatt gcgaaacttc accctttctt
     8281 ttgggtctaa tccaactgtc ggctcatcta aaatcaagat tttagggtca ttgagtaagg
     8341 cctgggcaat accgagacgt tgcttcatac caccagaata agaggcaatc cgcttcagac
     8401 ggacatcata tagatccaca agttttaaca attcatccgt ttcttgcttg gctttatgtt
     8461 taggtattcc ttttaaggct gccatataaa gaagaaagtc tcgaccagaa aaacgaccat
     8521 aataactaaa ctgttgaggc aaaaaaccaa tatgctgata aaattcctct gattgaggtt
     8581 tgtgatccag taaaatctct ccttcatcag gagtcgtaaa atgactaatg agattgagca
     8641 aggtcgtttt ccccgtccca ttagccccta aaagtccgta aaggcctggg gtgaattgag
     8701 tagtaatcct tcgcaaaata tttttcgatc cgtagctctt actcaattga tttaattcta
     8761 ataacataga accctcctta aatgagtcta ctgagcacct gtaactcagt actcagtaga
     8821 cttctcctgt acgaaatcct gctgtctgta acctttatta ttctcgtagc ataatcaaat
     8881 ccagagattt tcgattcatt aatgaaatat tgacgatgac acctttttaa tttcccagca
     8941 ctttctccct caatctgtct cagtgacgta gctgccccaa attccccttt tagggtaaca
     9001 aatactactg tgtgaggctt agatgaatgt gttgtcacat cataggtttc agagattggt
     9061 aatttaacaa ctgacctatt cttatataaa ataacatatt tcattgacgt cctccttctc
     9121 tatttatatc ttaatacaag tacaagcatt gagacggtaa agtctcaaat ggtatctatc
     9181 atatcctgaa tggtatcaca gtagctgttt aagatgtcat agaggcattt gagaaatgta
     9241 acctgttttc ctttcgtttt ttgatcatat gatattgtat tagttcggag aaccatggta
     9301 atcattcaaa tcttacataa acctctcttg ggatatggta ttagcgtcta tattaattac
     9361 tacttcaaca gacacctttt taaagctgct aaaattgtca gtggcaaaca aataggctat
     9421 aggtataaat ctcacactta ttttatcata aaatcattct ttttatcatc taatcaaatg
     9481 tacaagcact ttaaagttat tctcatgact ctattattct tattggaagc catattaatt
     9541 acgacgacat tttcagaaat cattatcgtg tgtttggtat catcgacaca accgctaata
     9601 aatcgtttaa atgtatccaa aaccaaattc atgattacct gttcaaagaa taaccagagg
     9661 gcttactgat tgctttaaca aatatttcta gtcttctcat tttgtactca tataaactca
     9721 tctactctat taaaaattgc tgtgaacaga aaaaccttct caacctgttt cagttttata
     9781 gccgtagtta gtttaaagtg aaaccaccct gcattttcta tacctaaatc caattgactt
     9841 gctttttcag catcaacagt catgctatcc ataagataac acaccacgat gtgttgtgat
     9901 tattgttctt ctatatttag ccttacctcc tgaaaacaaa aaaagagaac accttttaaa
     9961 tgttctcata taagcaatct tatatattaa atgaggattc gatctaatga caagacagcc
    10021 ttattgctac caataatgca gcttaccaaa caagggcaat cagtataagg gttgctaacc
    10081 agctctgctg acatagcctg ctttgagcga tcaatactcc ttctgattat agccaaagtc
    10141 agctaaatca agctttttgt cacgccagtt tttcttaacc ttgacccagg tctccagata
    10201 gaccttatcg cctagcatta gctcaatatc acgccttgcc agcttaccga tttttttgag
    10261 catggcgcct tgttttccaa taataatgcc tttttggctg tcacgctcta ccatgatggt
    10321 aactcggata tgcaccttgt cagtcacctc atcacgcttc atcgaatcga ccacaacagc
    10381 aactgaatga ggcacctcct gctgtgtcaa gtgaagcacc ttttcacgaa ccatctcaga
    10441 aacaagaaag cgctctgggt gatcagtgat ttgatcctct gggaaatact ggaagccctc
    10501 ttcaaggtta tcctttaaga gctgaacgag cgtttcgacg ttgtttcctt gaagtgctga
    10561 aataggaaca atttccttaa agtccatctg actacggaaa tcatcaatct gctccaataa
    10621 ttggtctggg tgaaccttgt caattttgtt gatcaccaaa ataaccggaa tacgagcagc
    10681 cttgaggcgt tcgataatca tatcatcacc cttaccacgc ttttcatcag caggcaccat
    10741 aaaaagaacc gtctcaacct cacgcagggt actataggct gattccacca taaaagcacc
    10801 taaggctgtc ttaggcttat gaatgcctgg cgtgtcaata aaaacaattt gctctgtctc
    10861 tgtggtatag attcccataa ttttattacg ggttgtctgc gccttatcgc tcataacggc
    10921 gattttttgt cccatgacat gattcaaaaa cgttgatttg ccgacatttg gtcggccaag
    10981 aatggcaaca aagcctgatt taaacataag ctactaaggg cctaaaggat cagtcaaggt
    11041 aagaatcaag cagcaggcta ttcacctgat tgctttccta aagcttatac tcctttcctg
    11101 cgctgcacta tcgcacagga tagcccattt cctttcattt ttttaatggc ataacattcg
    11161 ccaaattttg ggaacaaaga taatcagccc cgtcaaaaca gcatagcctg aaatgaccag
    11221 gacagcacct gcagccatat ccttggcatg cttagccagc atggagaaat ggtaatcact
    11281 tgccaagtca accacatttt caatagctga attgacaatc tctaaggtaa tcaccaaaaa
    11341 aatagccagc aataaaaaca gccattctat agcagaaata ccaaaaacaa tcccagccaa
    11401 agaggctaac agggctgaca aaagatgact tcttaggtta cgctcctcct taaaggctgt
    11461 cagaacccct gtcaaagcaa attctaagct ggcaattact gttctgtttt tccatttgcg
    11521 tttattattg tcttgtgagg ccataagcag tcaaaatctc ttcctgtaac gtaaacatct
    11581 ctttttcttc ctcaggagtg taatgatcat aaccattaat atgcaaaaaa ccatgaacag
    11641 ccaagaagcc catctcacgc tcaaaggaat gcccataggc ttctgcctgc tcatgggctt
    11701 tgtcaacaga aataaacagc tccccaatat aagcatcaaa ctcctgtatc atacctgcca
    11761 agtcaggatc aagctccaaa tcctcttggc taaaggcgat cggaagctct ggcttgtact
    11821 ccagagaaat cacatcagtc ggacgatcag tatcacgata ttcaagattc aaggcgtggc
    11881 ttctatcatt ggtcacaaag gtaaccgcca tttccttgtc ctctttacca attgttttgg
    11941 cagcaaaatt gagcaaatca atggtttgct ccatcatctc ttgagaaacc tgcttagttt
    12001 catcaatcat ctctatatac atcattatat gaagaggtcc tagcaagaca ggtccaaaca
    12061 aacaccacac tgctaggtca aaaagcttga tacctcttat cctttcaaca tcatttcagt
    12121 actttctttc cattatacca caagaaaaaa gaaaaagcag gcattagtct agcctgctcc
    12181 aaaagaagcc ggaataatga caagatcgtt gataccccag cagctgctgt ttctggaata
    12241 cccagagcct gctgcgcaga atacagtcct cttagatagc tgggactcct aggattacaa
    12301 tagtagataa gcctttagac cacttccatc gcctaaaaac taatcctaaa cggctttccc
    12361 ttagatacca ctagctgctc tcaaagctat tgtggaggta acgatctggc ttattggctg
    12421 acgccagtga tttctgcttg tcataatctt ctttggttaa ataatagtgc agcactgtca
    12481 caaaacggtt ggaatcaagg tgatcacgct tagcatatgg ctcttcatgt gaaaagcaca
    12541 tgccgctttt agccataaca cgtcccaaag ccggattggc tttatcatgc ttagcaatca
    12601 cacaattcat gcctaaagct tcaaaacaca agaccagtac agccttgaca gcctctgtcg
    12661 catagcctct tccccagtga tgcttatgaa gacaatagcc aatctcagct ctacctaaat
    12721 ccagctgtat atgatgaaga tcaagcgtcc caataaagtc tcctgtttcc tttaacacaa
    12781 tcccccaccg tccaagtgga ctagccagat agacagaagc aatgacttga cgggtctcct
    12841 caattgtctg attggctgga aagctatacc tgacagtctc ttcatcagaa gcataatcaa
    12901 acatggcttt ggcatcatcc aaggtcactg gacgcaggca tagacgctct gtctcaagat
    12961 acctatgctc tgctagtttt tcaaaaaagc ttgccactac tactctccct ttcctaaaaa
    13021 tctaactcac ctaacagcat gactgcctgc cctagccgcg taaaatctgc ctcaccttat
    13081 cctttaaaac aggaaccagc tcctcttcaa accaagcatt tttagccaac caaagctgat
    13141 ttctaggaga tgggtgaaca aggggaaaat aatccggaag atagtcctca aaatgctgca
    13201 ccgtttcggt aagattgcgt ctacaacctt caccaaggta atattgctgg gcatactgtc
    13261 cgaccagcac caccaattca acctgaggca tcaaggccat taacggacca tgccacttgg
    13321 cagcaaagcc ctttcgcggt ggtaaatcac ctgattttcc cttaccggga taataaaaat
    13381 ccataggaag aacgccaaac aagcccgact gataaaaggt cctgtcatca acacccagcc
    13441 aagctctcaa gcgaactccg ctacgatcat tccagtacag acgcgtctcc tgagctacaa
    13501 taccaggcac ctgaccaaca atgactatcc gagcggtctg aggagctgca taaagtggtt
    13561 cgataccttt tttggtatag tcacgattgg caggatcagc cataatcgct tgcaatagct
    13621 ctgtcatgat accctcactt tcataaaagg ctcttcaggt gaagagctct tttttacgat
    13681 ttgtcttctt taggcagctc tccaatgacc tcataggttg ttaagcctga cgtagactga
    13741 cccgtctctg ttttaggccg atctggagcc ttagtctgat gttgcagctg attagggctg
    13801 ctttttaatg actctgcttt tgaacctaca gtttcatagg ccttaataat ctcagcaaca
    13861 acagggtgac gcaccacgtc cttggctgaa aaatgcacaa aatcaatctg cttgatggcc
    13921 tgcaattttt gagctgcatc aatcaagcct gatgtgatat gacgcggcaa atcaatctga
    13981 ctaatgtccc cattaacaat cattttagac tgaaaaccaa gtctggttaa aaacatcttc
    14041 atctgcatga tggtcgtgtt ttgcgcctca tctaaaatca caaaggcatc atctaaggtc
    14101 cgaccacgca tataagccaa gggagcaatc tcaataatat cacgctccat taaccgagta
    14161 gtctgctctt taccaagaat ctgataaagg gcatcgtaga ctggtctaag gtaaggatca
    14221 accttttcct tcaaatcccc tggtaaaaag cctaagcttt ctcctgcttc aacagctggg
    14281 cgtgtgagaa tgatccgctt aacctgacca cgctttaaag cagtaactgc tagcgtaact
    14341 gctaaaaagg tctttcctgt tccagccgga ccaataccaa ataccacatc atgatgcttg
    14401 atactatcaa cataggcctt ttgccctagc gtcttaacac gaattggctt gctataaaag
    14461 tccttgataa tctcttcctc ataaagagca acaaattgat caagcctatc tgaatccgcc
    14521 atagacagcg cagtcaccac atcagaggta ttgataacca tgccacgccc caccaaaact
    14581 aaaagggctt gtatcgtcaa acgcgctagc tcaacagccc gctcatcatc accaataatc
    14641 tgaactcgct cagttctagc atgaatcaca acattgaggt gagattctat catcttcaaa
    14701 tggcgctcat tgctaccaaa aagagctaac agatcatctg ggtgattcaa gctaatgtca
    14761 gtcgaataat gcaaatttgt cttccttttc catctataag taactctatt ataacaaatt
    14821 ttgctataaa tcgggaataa gacccagctt taaagcctaa aagagctagc ctatggctag
    14881 tggctaaggt aatcctccca aatctggtca aactgcccca gattgaatga aaagctcgct
    14941 tcctcttcaa ggtaacgact gatggtctca aaatcatctg tatgctttgg aaaggtcggg
    15001 tcctcaaaaa ccaaatcagc taataaagca gcaggcttat tagatgtcga gttgcgctga
    15061 gccatcagcc aagtgtaaaa cgcctttctc attgccaatg ctcctccaaa aattgatgac
    15121 gaatagcact actttgtgca taacgctctg gattcttttg ataaaagccc tgatgatagt
    15181 cctctgctag ataaaaaggc tctgccggtt caatgcttgt cacaatgggc tggtcaaagc
    15241 gccctgaggc ctgcagggtc tgcttggacc gctctgcaat ttcccgctgc cgctcatcag
    15301 tatagtaaat caccggccga tagttgtctc ctctatcctc aaattgccca aaggcatcgg
    15361 tcgggtctgt ctgagcccag taaagctcta ccaaatctga atagctgatc agactcggat
    15421 caaagataat ctcaacagct tcagtatggc ctgtcgtctt tgagcaaacc tgctcatagc
    15481 ttggattgtg aacatgccct cctgtgtagc cacttctcac tgataaaata cctgcctgct
    15541 cctcaaaagg ctgcaccata caccaaaaac agcctcctgc aaaaattgct ctttccatac
    15601 ctaatctcca ctttctttgt ccttacatta gtgattttca ttgtaacaaa aaaccttgcc
    15661 agaggcaaag cttaatataa aacaagtcac agactcaaag taacaagact cctcagccca
    15721 actagtgcct agcactaagc agtactgtca agcagccact actagatcaa gagggccaca
    15781 cagagctttt tcgacaacaa aaatgattgg cgctttaaaa caggctatca gctaagctcc
    15841 acactcaaaa taaggaagct agctatactg ataaaggata agtcttagca acaccgatcc
    15901 agcttatgat tataggctaa gagacagaca gctccctatg atatcagctc agttcctgtc
    15961 acgtcctgct tgatcttgtt agccttcatc aaaccaccta aggccttttt aaattgaccc
    16021 ttggaaatcc caaaggttgc cttgatatcc tctgggcttg acttatcatt aagagtcatg
    16081 tagccaccat tagacttgag ataggtcaga atcatctggg catcgttttc cagcatttca
    16141 aaggaacgcg gctttagcga aaggttgagg gtacggtcac gttctctaaa gccaatcacc
    16201 cgagcggtca aaacctgccc caaacgaggc tccgtataac gctcgctagg gtggataaag
    16261 cccagcatat tattttctgg caggtaaaca aaggtccctg atagcttcaa gcgatagaca
    16321 atagcaggca ggctttgatt ttgcatgtta tcataggctg gactagcaag cctttgaaat
    16381 atctctggct cagctggcaa accccagata cgatcttttt tgtcaaccac aagcttaaga
    16441 taaagcctgt ctcctttttt aggccaaaga tcctttagct ccggcaaaac atctaaggaa
    16501 accacaatct ccttatctgg aataccagta tcaacaaaca ccccaagatc acgacggaca
    16561 gtggtcacct cgccccagcc ataatgatca cgccttgcgt caataggctt cgtggtcaag
    16621 cgtagtcttt gcttcatatc tgtatagaca aagcccttaa ccatatctcc taatctatga
    16681 ctgccttcct ccttagctag agcaaagctc agcccctcct tttggacaag ataaaactga
    16741 ctattttctt cttttactaa gccagtgata actgttgcta ataaatgatt catatctttt
    16801 tgttctttct tttaaaaaat agggacaagt ccaaagcagc tgctttttag ccttgtcacc
    16861 tatcctgtta tgcctgatgt gtattaggtt acgcagctga tctagcttaa tgatcagata
    16921 agccgcttaa actgaaagta attccttttc tttgtcagca gtcattcggt caatctcttt
    16981 gacagcctca tctgttgctt tttgaatatc cttttccaag gcttttaact catcttcagt
    17041 gatttcctta gccttctcct gctttttagc ctcgtccata gcatcacgac gaatattgcg
    17101 aatcgaaacc ttcgcagtct caccaacctt tttcacttcc ttggctaatt ccttacgtgt
    17161 ttcttctgta agcgctggaa taaccaagcg gatgacagag ccatcgttag ctggtgtaat
    17221 gcccaaatca gaagcattca aggcacgctc aatatccttg attgatgatt tgtcaaatgg
    17281 tgaaatcaaa agcacacgcg cctctggtac tgtaatagaa gccaattggt tcaacggcgt
    17341 tggtgcacca taataatcca cctgaatacg atccaaaagg ctagcattag cacgacctgc
    17401 acgaatgctt gcatactcgc gtgctagtga gtgatgtgac tgtgtaaaac gttctttcgc
    17461 agtttcaata attgcatttg ccatgattgt ttttctcctt aatcctttag ctctaaaatc
    17521 ctaatcgcag gccttatttg ataccgttgt gccaatatgc tctccaaaga ccacacgctt
    17581 gatatttcct gcttcattca tattaaagac aaccaaatca atatcattat ccattgacaa
    17641 ggttgaagct gtcgcgtcca taatcttgag accgcgcttg ataacctccc catgagtcaa
    17701 ttcatcaaac ttaacagcgt ttgcgtcctt tcttgggtca gcattgtaga caccatcaac
    17761 accattttta gccatcaaga tagcatctgc ctcaatctca gcagcacgta aggccgctgt
    17821 cgtatctgtt gaaaaataag gtgacccaat accagcaccg aaaacaacaa tgcgcccctt
    17881 ttccagatga cgaagcgcac gacctcgaat ataaggctct gcaacgtttt gcatgggaat
    17941 agctgtctgc acacgagtat caacgccata atgctgaagg ctatcagcca ttactagagc
    18001 attcataacg gttccaagca tgcctgtgta atcagcctgc acacgatcca taccagcctc
    18061 tgcagcaggc tcaccgcgcc agagattacc accaccaata acaagagcaa tttcaacacc
    18121 tgaattgtga acttctgcga tctctttagc aatcgactga accgttgtta tgtcaatgcc
    18181 aacaccctta tcaccagcca aggcctcgcc agacaatttg attaaaatac gttgatattt
    18241 aggtttcact atttatgatc tccttatttt gtccctacca ttctaccaca aaacaaaaaa
    18301 atttaataga ccaatgcaag agaggaaagc gaaatttttg acgatccttt tatcaagatc
    18361 cctttgagca gcaaaaaaga tgagtcatta taaaaagagc attatcgtat ccgaatagca
    18421 cagttataac ctattaatac gacaaaaacc agaacaacta tgacaaaaaa acgccgtaaa
    18481 aaagacttaa aatcaagcct caagccagac tagattctaa gtcgtgctat attgagagat
    18541 gatttgtttt agttatctag cccaatgccg ccacaagaag tctgaggctc cttatctctg
    18601 acagcaacta gcctcccctg ctccagcagc agaacacgat gacaaatggc ctgacagata
    18661 ttagcatcat gcgcaataaa aatataagtc agttgatact cctgctttaa ctcatagagc
    18721 aagtccaata gctgcccttg ggtaataggg tccaagccac tcaaagcctc atcaaaaatg
    18781 atcacctccg gccttaacaa aagagctctc gctatacaaa cacgctgtag ctgaccacca
    18841 ctcagctctc tggccttttt acccagatga gtggcgtcaa gaccgaccgc agctagtatt
    18901 tgaacaacct cctctaaggc aaagtcctta gaaagggcct ctgtcaatat ctcttgaata
    18961 gtaaagaggg gattgactga tcttagcgca tcctgaaaga caagtaaaat ccgaggtcca
    19021 catactttta cagaataggg ctgaccatga aagagcacct gaccagctgt cggctgctct
    19081 agcccaatga ttaacctagc aagcgttgtc ttgccactac cactttctcc cataatccca
    19141 aggctctcac ccttttccat ttgaaaatga caatctgtta gcactggctt ttgatgaaag
    19201 ctcttataaa catgtctaaa ctctatcata gcgtatcagc cgatcataat gattttgcaa
    19261 aagcaactcc ttggtggcag cctgacttgg ccgatgaaaa atcgactcaa cacttccctg
    19321 ttcgatgatt tttcccttac tcatcaccag tagttgccct cccaaagtct gtgccaattg
    19381 gtaatcatgc gtcactgtaa taatggtttt tcccttgtcc tgcaataact tcagcatccg
    19441 tatgatatta gaacgattgg catcatctaa agcagaggta ggctcatcta aaatgataat
    19501 ctgtgggtct aagcacaaca aaatagctag cattacccgc tgtagcatac caccacttag
    19561 ctcaaagggg tacttcctca gcagctcctc tggctgctct agatagagct ctcgcatgaa
    19621 aggcagagcc ctttttagac aggccctttt tgaaagtctc tcatggcttc ggatggtttc
    19681 aaggagatga gcctcaatgg tctgaaaggg attgaacatc gccataggat tttggaccat
    19741 ataggccatg tggcgccctc taatgctctg ccattgctta gcatctaatt gatctagtct
    19801 catatcttga caggtaatcc tccctgtcat ctgtacattc gacgggcatt gaccaattaa
    19861 tagcttagtc aagagggtct tgcccgaacc actcctgcca acaatcacca aggagctccc
    19921 caagggcaac tcaagattga gcttacttaa tagcacatca gagccattat aagccgataa
    19981 atcattaaca attaaccgtt ccatgttttc ctccacccct tagcatcagc gtaatcacct
    20041 aggctgttaa aagctagcac agtcactaaa atggcaagcc ctggtgacat catgagccac
    20101 agagctgtcc taaaatagct ccttgcatca tgcagcatca ttccccattc tgtcacattg
    20161 ggctgaacac cgatacccaa aaaagaaaag cttgagatca tgagaataat attgccaata
    20221 ttcatcaaag ccaacactac aatcggccga taaacaaatg gcaggatatg cttttttaag
    20281 atatgccgca cagataagcc cattgtctgc gcactaatga catatggctc tgccttagcg
    20341 cttttgacca tcgtgaccat cagcctagca taatacagcc actctaccag aacaatagct
    20401 aggatcatgt tgcctatgcc ctgcccaagt atccccattg tagctagcga tagtaaaaag
    20461 ctaggaaagg cagaaacaac atcagctagc cacagaaaag ctgcctcgag ccttccttga
    20521 taccagccta caaccaaacc aaccacagca ccaatagata gctctaacaa actaatagta
    20581 accgccaaaa gcaaggaata cttagcccca tataacaagc gcgacagcac atctcttccc
    20641 aattggtcag ttcctaataa gtgctgctga ctaggtggca tgagcttact agcaacatca
    20701 acagcatgag gatcaaaggg agcaagataa ggagcaaaca agacacagat aaacaacagc
    20761 aatagcataa cagctgaacc aattacgtat ttgggcatgc ttcctccttt gtcttgcgca
    20821 gacgagggtc aataaaagac actagctctt gagttatcac atggtgtagt aaaaacaaag
    20881 caccaaataa gagcatacag gcctgaataa ccggaatatc tgctgctttc agactcataa
    20941 caaatagact gccaatacca ttccatgaga aaatatcctc aacaataata gagcccgtca
    21001 tcaaataaac aaaggtcaag ctcaagcctg ttgcaatagc aggaaaggca tttctaatca
    21061 ggtgatgctt aacaatataa taggtcttaa cccctcttag cctggcattt tcaacatgca
    21121 gactcgttag ctgctcactg attgcctttc gtatcaaggc agtatattgc ccaatcaagg
    21181 aaaagctaag cgtaatactc ggcaaaatga ggctgctggc acccgccttg cctgacacag
    21241 gcaggagatt tagcttaaca gaaaaggcta taatcaagag atagcccaac caaaagctag
    21301 gcattgacac agcgacaaag ctgaataaac gcaccagccg atcaaacaag gaatgctcaa
    21361 acaaaccact gcctaccccc aaaggaaagg caatcacaag taccagtaaa aaagaggtca
    21421 agcttagcat tagcgttgct aaaaagcgct ccaccaccaa aggcaggaca gggaccttta
    21481 acacgtaaga ggtcccaaaa tttcctacaa gaatgtcaga taaccaggtc acatactgct
    21541 cccataaagg cttgtctaag cccaaataga gcctagcatt gtgaagagct tctggtgtaa
    21601 tactgatctt agataggcgc aaatactgct ctgccgggtt agcggaggat agcttaacca
    21661 gaacaaaggt cactatcgaa atcattagca aggcgccaaa ggtagaaata agcttcttca
    21721 tcatattttc tctcaaccct tcactaagac atcagacaag aattgtcagg atagtcactc
    21781 acaaccagtt cctctgctct atcaattctt gactgcctta tcagcagcac ttttttcaat
    21841 gtaacgcaat ggaagggcat tttcctctgg tgcaaagcgc attgtcttaa aatctccctt
    21901 gcgatatact gaaacaactg actgataggt gagtggaata taaacagcct catcatgcaa
    21961 caatgacaat acctgcttat agcccttgtc taccttatcc ccatctggct caatcaaaac
    22021 agatttaatc aggcgatcaa tctcagcctt tgatggcaaa ctctccaagg caatattttc
    22081 tgggtgacca tgatccgctt ttgccgttaa ggctgtcatc caagcatgag gatcccaagg
    22141 agctccccat gaataggtca gcatcatatc aaactgccct gtcttggcat tagcccagta
    22201 gtcatcctcc tccatagctg tcaagaccac atcaatccca agctttttcc actcgccttg
    22261 gaaatattca accaaatcct tgtctgtcgc tttagttgaa atataaggca cctgtaaacg
    22321 caactgctga ccatcttttt ccctaatccc ttcttggttt tccttccagc cagcggctgt
    22381 cagcatgtcc ttagcctttt ggagattgta ttcataagga actaagcccg catcagcatg
    22441 cggtgttgtt tttgaaaaaa tggtatctgc tgctgtctct gttcctctaa aggtgtgctt
    22501 agcaatagcc tttttgtcaa ccgcatggtt cattgcctga cgaacccgct tgtcctgaaa
    22561 cactgactgc ttagcattta acagcaataa acgagtcgac atgggctgag aaacatcagt
    22621 aacatacttc ttgtccttag catactgcac aaaggtatca agactaatca gaccatttcc
    22681 atagatcaaa tcaatatccc cagcctcaaa tgctaaggct cttgtctcag catcaggcat
    22741 aatcttgatg gttacttcct ttagctttgg tttttctccc caatagctct catgacgtgt
    22801 aaaggtaatg tactcatttg cctttttctc tttaacaacc cattgacctg taccaatcgg
    22861 ctttttaaca ttgtgcttat tggtgtcatc gccatcagga aaaccagcat cagccaaaaa
    22921 cctaatcggt ctgatcattg acaaatcata caaggtagcg ctataagcct cctttagctt
    22981 aatctcaaag gtatgatcat ctaaagcctt gtagctatcc aattgattgg taaagtgaaa
    23041 ccaattatga ttgcccttat tctgctcaga gaaaatcgaa tcaaaattcc gtttaacatt
    23101 ttgagcatta aaatcagaac catctgaaaa tttagcctgt ctcaggttaa aggtataggt
    23161 tttgccatct gggctaatcg tccagctctc tgctaacgcc ggctcaatat tacccttgtc
    23221 accatatcga accaagccct cataaaccat gtcttgaata acaaactgat caggattgta
    23281 gcgatgagga ttgacatcac caaaatcctc accccaagca atcctcaact gatccgtacg
    23341 gtaagaggcc tgcttagcat tttgacaggc cgtcagcagc aaagcaaaaa agaataacaa
    23401 tagcacattc aatttagttt tcattatgtc attaactttc taaagatatt aatctatcta
    23461 attttagatg tggtttatca caaaattaag tatggttaat ttaatcattt tatagccctc
    23521 ttgtcaagaa aaaatgagac aaaatcagcc tagaaaaagc cagaaggcta caaataagca
    23581 aatcgtcaaa atcatgaaca cttcaggctt gctgaggaat attttctaat ggttattaga
    23641 aataatgaac aattacctaa caaaagactc caaaataaag gtaaaagacg aacattcacc
    23701 ttgctgctca gctaccaaga caaacaatcc tgatagcatc aattttcttt aggctcttag
    23761 caattagttg caatatcaga taattttgaa tttaattaaa aaaaacgaaa ctacggagac
    23821 caattatcag aaagctattc acagccagca aagggcatgc taaagtatta tctggaaaaa
    23881 gaaaggctta ggaatgatta tttctaaact aaaaggagag agacaatgaa aaaaacaatg
    23941 aagaagatgc tagcagcctc gacgctctgt atcatcatgt caggcagctt catcagcggc
    24001 tcagctagag tgttagcgga ggaatattat gggtggaatg atgtcactgg gtctaagtca
    24061 ccatttcctc tatacgtgac accaaaaaat ggagataaaa atataaaagt tcaacaaacg
    24121 gttgtttact gttttaacag ggatgggcaa tggccagaaa attgggaaaa acggatatat
    24181 gaatctcctg ataaagttcc acataaatta cccgaatata ataaaaagtc aggaagcgat
    24241 aatctgtttc aattacttaa tcccaaaatt aagataaaaa atccaatggc agctttatta
    24301 gcggttttgg aagatggata tcctacgtca tcttcttcag gagtaaatca aagaacaact
    24361 cagctagcta tttggcattt tacagatgga ttaagcaatc ttgcccaatt tcatcttact
    24421 ccggaagaaa cttcagctta taacaagttg atagaaaaag ggacaaatgc ttctaatcaa
    24481 agtgaaaata aactattaaa taaaacttta gatatttatt cctatataga tgggactggt
    24541 gataagaaac acaattatca acaccttctt ggctccactc caattcctat tgataattct
    24601 aaagaaaata aatgtcaatg tacaaaagtt gacttaatgc gaactggaga tggggttaaa
    24661 atcattgttt atgttgataa caacggaaat aatagatatg acaacggcga caaaatgcta
    24721 aaagaagaaa ctatcaaaca tggtcaacgc ggacctgctg gtgaatctgg gaaaccaggg
    24781 cctaaagggg atcgaggaga aactggagca cgcgggccag ctgggcctca gggcaaacct
    24841 gggaaacaag gacctagagg tgataaagga gaaaccggag aacggggacc tcaaggggaa
    24901 aaaggtgaac ctggaactcc tggtcctaaa ggagaagacg gtaaagacgg ggctcctggg
    24961 cgtgacggac aaccggggcc taagggtgaa aaaggtgacc ctggaaaaga cggacaagat
    25021 ggaaaaccag gggaaaaagg agaacctgga attcctggtc ctaaaggaga agacggtaaa
    25081 gatggggctc ctgggcgtga cggacaaccg gggcctaagg gtgaaaaagg tgaccctgga
    25141 aaagacggac aagatggaaa accaggggaa aaaggtgacc ctggacgcga tggtaaagat
    25201 ggagaaaaag gcgaacgcgg tgaacaaggg cctaaaggag aacgcggtga gcagggacct
    25261 caaggagagc gtggggagca aggacctcgt ggggaaaatc atactcctac cccagaccca
    25321 atgcctgagc cggcacctaa accagaatcc aaacctgaac ctaagccgac acctcaacca
    25381 gaggttaagc ctctgccaga gactaaacct caaaaaccaa ccaagccgtc agcaatggct
    25441 agccaaccaa gtagcaaagc actaccaaaa acaaatgaca ctagcggctt aatgactgta
    25501 cttggaacag gcttgctctc tcttcttgga ttaggcttcc tggcaaaacg caaaagaaag
    25561 caataactaa cacataatca ttagtaatcc attcattatc catttacaag ttatcataaa
    25621 aaagccttat cattccttga ctggtatgat aaggcttttt gtttacccta tatagctcta
    25681 cccttactcc aaaaatcact taaccctagg aaaaggctga ctatcatttt tggccaaaaa
    25741 aagacagaca ccaattcatg atgtctgtct caaaaccaat cccttttagg gtcagtcctt
    25801 aattacttat taaaatgaac ttggatctac cttgataccc acaccttgtg tagttgtgat
    25861 agatacgtta gtcatgtaag taccctttgc agtagctggc ttagccttaa ccattacctc
    25921 atggaaagcc ttaaagtttt caaccaactt gtcagcgtca aatgatactt taccaatgat
    25981 agcttgtacg ttacctgctt tatcagcacg ataggtaatt ttaccaccct tagactcttc
    26041 aaccgcctta gcaacgtcca ttgttactgt accagtttta gggtttggca tcaagttacg
    26101 aggtccaagg acacgtccaa gacgtccaac aatagccatc atatctggtg ttgcaataac
    26161 aacatcaaaa tcaagccagc cgccattgat cttagcaaca aggtcatctt caccaacgaa
    26221 gtctgcacca gctgcctttg cttcttcagc ttttgctcca cgagcaaaaa caaggacacg
    26281 ctgagtttta ccagttccgt ttggcaacac catcgcacca cgaatttgtt ggtctgcctt
    26341 gcgaacgtcg atgtttaagt tataagcaac ttctacagaa gcgtcaaatt ttgcgaagtt
    26401 agtttctttt gcgagtgcta cagcttcctc tacactgtat gcctttgtgc tgtccacttt
    26461 ttcaagtgct gcacgcattt gtttgctttt tttagccatt tttatcttct ccttgtaatg
    26521 tggtcatatc gatttgattt aaaaatctcc cacgtcactc atctctatga tgaagtcttg
    26581 cgggtaataa gggcaggttg ctgattaatc agtaacggtg aatcccatag aacgagcagt
    26641 accttcaatc atacgcattg cagcttcaat gtttgcagcg tttaaatctg gcatcttagt
    26701 ttcagcaatt tcttgtactt gtgcacgagt aactgtcgca actttagttt tgttaggtgt
    26761 acctgatcct ttttcaacac ctgcagcctt ctttaaaaga acagcagctg gtggtgtctt
    26821 tgtgatgaaa tcaaatgatt tgtcttcgta aactgagata acaaccggga taatcatacc
    26881 agcctgatca gctgtacgag cattaaattc cttagtgaat cccatgatgt tgatacctgc
    26941 ttgaccaaga gctggtccaa ctggtggagc tggtgtcgct ttaccagcag ggatttgaag
    27001 ttttacaagt ttttcgactt ttttagccat ttttaaaaat cctcctgttg tggttttggc
    27061 ggtaattcac gatttttacc tcccacaggt atgctagagc ataccttacc attatacctt
    27121 attagacaga taaatcaagt cattttcaca aaaatgttac cgcaaatagc agatgtctcc
    27181 tatggcacta gcagtacaag catgtgaggc ttccaaggag ccgcttctag ttgactttta
    27241 agcgtttttt tattataaca aagctatgca taagaaagtt acgatcaaag atgtcgcacg
    27301 cgaggcggga gtttctgtgg ctactgtctc ctatgtcatc aataacagag aagatcaaaa
    27361 aattagccct gaaacgcgca ataaagtgct gcaaatgatt aatcttttaa attatcggcc
    27421 aaaccaagcc gcaaaatcac tcgtgacaca aaaaagacag ctaatcgccc tttactacaa
    27481 agagcacagc tctgttttaa aaagagcaga gcagcttcac tttatcaccc agctatctgc
    27541 ctttctttac acaaagcact atcacttgat ttgccttaat caagaataca tcggaaaata
    27601 tgatgtagca gatgtcattc tcaccctaga ggtcaccaaa gaggaatttt acaagatcgg
    27661 aaatagcaac tttgttcctt tgattgctat tgatagtatt attgatgatc ccttattttt
    27721 ccagattaat agtgaccctc atctcctgtt caataaagcc agtgcttatt ttgcagggga
    27781 gccctttgaa ctggttagcc tgcctattca aaaccaagaa atcactcaag gactcgctca
    27841 acagtttgat aacatttgct ggattcactc tatttgcgac atcgaaagcg tgtctaaggg
    27901 gaatattcta gttattgatg atactgtcaa tcatattctt agtaagcaca agaacaaact
    27961 atacctgcca agtatctcag aagctaagct tctgaagctt tttcaggcta ttgagtgggc
    28021 ttccaaaaga gaagcaatca acaatcataa tattttggtt taaccatgat aagagcttag
    28081 caacaagctt gctgctaagc tctttttgtt ggtcaagagg ccaactttat ttaggtatca
    28141 gtcagtgtgc cagctctttt agccactaaa agcaggaatt agtttacaag tctaccaatt
    28201 gggtataaaa tagacttatg atcatctaca aattaacagc cttagccttt attatcctga
    28261 ctcccttatt ctctatgata atgatatccc tattgagact gggacgaaga ggccttaaat
    28321 ttcctgattt agccttacca ctttttgttt ttgaaattgt tattgtatca ggaaaatttt
    28381 tcacccatca tttactacct tattacctga ttgttatgtc cttgttggcc attgttatgg
    28441 cactcttact gattatcaga atccagcagt tttcttaccg ccgatttttc aaactatttt
    28501 ggcgagtagg ctttttagtc acactactct tttacctgat gctagttggt cttattttta
    28561 tcgtttagtg ccttaccaga catggcttca agcctagcag tctgaatctg ccaattaact
    28621 ctagcactat cactcaaaag gaagctgtct ttgaactttc tgcttgagtg ggactttttt
    28681 caaagcaatc aatccatatc aaaccagcat tagagcatgc ggcttgatac ggattgattg
    28741 ctttaagaac tgttgtaaaa tatcaaaaat tcagttttta ataaagtcca ttagctattt
    28801 ctacactaaa tatcatttaa gaaaacagag gctaataact agagttcact ataacctaaa
    28861 atcaccaata cctccgatta acttaattta accaaactac tgtatatacc aaagtttttt
    28921 acgtgtcatt ataatacgtt cagataaatc atctaatgca cgatctttgt tgagaccaac
    28981 atcatattga atacccatta atctatctag aaactcaaga cgatatttct tcataatatt
    29041 tcgtgagtgt ccttctggaa aatgctcatc aataagcgaa cttacaatct caactttatt
    29101 actaatttta aaatagcgac ttttcaaaga ttgtaattct tctttaattg ctcttaattt
    29161 agaaaaacta tctgctccat aaaccttagc ttccatttca ttagcctcag aataacttag
    29221 ttttattgtt gcaataaaat ttctaagtac ttccttctct tttttaagct ccctttctgt
    29281 cggactcatt ctatagtaat attgacgcca acgatattga gaagcgttga ctttttgatc
    29341 acttatagtc aaaatagtca atgctactac actaaagaaa aatattcttt tcgtttgcag
    29401 tttctcctat acttcataat gtactatttg tatataaaca caacataacc aagcattagt
    29461 atatcagaaa actttcttaa atatgtgata ttagctaatc tttttttaaa actctctata
    29521 tattaaggta ttatggacat attgacttag cagattagat ctgccaatta gctctagcac
    29581 tatcactcaa aatgaagctg tctttgagtt ttctgcttga gtgggacttt ttcaaagcag
    29641 catatcaaaa acccgtatca agccacatgg ttaagcttag cttggtacgg gtttgtttta
    29701 tgatgagcct ttagatgagc tcttttttaa ttggtttgca gtacctttct tggcttagtc
    29761 ccctcagctg gaccaatgac accggcctct tctaattcgt ccattagtcg agttgctcgg
    29821 ttaaagccaa ccgatagacg cctttggagc atcgaggcgc ttgccttttg cgtttccaat
    29881 acaagagcct ttgcttcctc aaaaagggga tcaccctcag gagctccgct gctgccataa
    29941 tcagagtcac taacctcacc cggatcaaaa taatcatcat aatcagcctc tgcctgctcc
    30001 ttgataaagc taacaatgcg ctcaacatca tcatctgaaa taaaggagcc ttgcagacgc
    30061 acagggtgat tctcatcaat cggcttaaag agcatgtccc cgcgaccaag cagcttttca
    30121 gcgccatttt catcaagaat ggtgcgacta tctgttcctg atgaaaccgc aaaggcaata
    30181 cgtgatggaa cattagcctt aatcaatcca gaaataacat caacagaagg tctctgagta
    30241 gctaaaatca tatggatacc tgctgcacgc gccttttgcc caagacgaat aatagcatcc
    30301 tcaacctcct tactagccac catcatcaaa tcagctagct catcaacaat aacaacaatc
    30361 atcggcaaag ggatttgctt ttgctcagat tgcttgttgt aggcttcaac cttggcattg
    30421 tagcctgcaa tatttcggac accgacctta ctgaacagct catagcgatt ttccatctca
    30481 tcaacaacct tctgaagcgc tttgcttgct ttacgagggt tggtgaccac cgggattaac
    30541 aggtgaggaa tgtcattata aacagacagc tcaaccattt tcggatcgac cattaggaat
    30601 ttgacctgat ccggtctagc cttcattaaa atactggaga taataccgtt gactgcaaca
    30661 gatttccctg atcctgttga gccagccacc agcaaatgag gcatgcgggt caaatcaaag
    30721 cttctggcac taccgttgac agccttacca agaggaattt ccaataattt gtcatcagat
    30781 gtgttggatt gctcccaaag ctcgcggaaa gaaaccgttg caacctctga atttggtacc
    30841 tctataccca caagggattt gccagggatc ggagcttcaa tccgtacgtc cttggctgcc
    30901 aaggccaagg ccaagtcatc agctaaattg gaaatgcgat tcacacgaac accaacagcc
    30961 ggcttaacct cgtatttagt tacagatggc ccaatctctg cccgctccac cttgacgtca
    31021 attccaaagc ttctgaaggt atcctctaat accttgatat tttgacgaac aaggtacttt
    31081 tccttgaatt gatttttagg cttatcagca gcaaacagct ctatcgtcgg cagcttgtaa
    31141 agcagattgg tctttggcgt gaaatcgacc tccactgaca gctcctcatc atctgacagc
    31201 ggcgcctctc ctgcgattgc tgaagcaccc gttagagggg cttctggtac agactcctct
    31261 tcatctccaa atgcctcagg ctcatcatca gcagggtgtg agtcataggc cagaatttcc
    31321 ggctcaaaaa atgcttcaga ctccttctga tcagccatct ccatcaatag gtcttctggc
    31381 tctgctaaaa gctcacctgt ctcaggatta atcgcttgat tggccagata ttcttgctcc
    31441 tccaaggcct ctcttgctag acgctcctct tcagccagca atcgttgctt ttctcgctca
    31501 acaaaccgct tttccttgtt ttcttgatag gccagggata gcttttcaaa aagcgtctta
    31561 acaaaatgac tgacgtcata aatatcccaa ggggtcatta aaaacaagcc cagcaggata
    31621 aacaaaaaac caataaaata agagccaata ttagaaaaca agaaggaaat aggcttgtac
    31681 agcatggccc caagcatacc accaccaaca aactcgctaa ccttaaaggc tagcaggtca
    31741 ttggtgatta gctggatagt cccagcaaca atagcctgat gagctagctg aggcaatgag
    31801 aaaagatagg catgccattc aaccagaagc cctaaaaaca agatgataaa gccagcgata
    31861 aggccatctt tttgcctgag ccacttgaag aaaaagaggt aaaaaaggac cgccaacatc
    31921 aagagattgg ctaagtcgcc aaccataaag cgaataagat tatataaggt aaccccaagc
    31981 gcacctaagc gaagcatggc aaaaacaagc aataaagcgc aggagaaaga agcaatcatt
    32041 ctcttaatag ccttttgctt ttcaagctct gcctttgtta aacgtctctt agggggattt
    32101 ttttgtcgtt gagttcttct agccatagcc ttattataac attttttaat cgttatgaaa
    32161 gatgacatta aaattctcaa taaatagatg aagctgcttg attttatgct ataatgtcaa
    32221 tcataagaac aaataggagt tgaagatgga aaaagaattt aacaccttga cctatggtaa
    32281 gcttcccctg caaattgata tggggcatgg caagctaatt cccaaaggag ttgaagtcaa
    32341 ggctatcgtt gatatgcaga ccgggcaagt caccttcaag gtttctcagg aggacttaga
    32401 gaagcttaga aatagttaaa aaatagactt cgtctcaatg ccctttagct ttattttcca
    32461 agtcatttta tgttaaaata aaagaaattg ttctaaggag tacacatgaa aaaactacta
    32521 tcttttggct taatcggtct tgctttgctt agcttaagtg gctgtgagtc cattgatcgt
    32581 gctattaaag gtgatgaata cgtcgatgaa aaaatcgcta gagaggaaag cgagacagca
    32641 gcaaaggctt atgaagcaaa aatcaaaaaa gcactcaagg ctgacgctga tcagtttcca
    32701 caattaaata aagaagtcga caaagacgaa gctaaggtca ttatcaaaac taatcagggc
    32761 gatatcaccc tcaagctctt ccccaagtat gcaccgcttg ctgttgaaaa ctttttaaca
    32821 cacgccaagg aaggctatta cgacaaactt ttgttccatc gggtgattaa taactttatg
    32881 attcaaaccg gtgatccaaa gggagatgga tctggcggag aatccatttg gaagggcaag
    32941 gacagcaaaa aagatgcggg acaaggcttt gctaatgaaa tctcaccatt tttatataac
    33001 attcgagggg ctcttgctat ggcaaatgcc ggtgcagata ctaatggcag ccagttcttc
    33061 atcaatcaaa gcaagctcaa ccaagccaag gccttatcaa ttgataatta ctctaagcca
    33121 atcattgact cctacgaaga agggggtaat cctagcctag atggtggcta taccgttttt
    33181 ggtcaggtta ttgagggtat ggatatcgtt gataaaatag ctgccagccc agtcggccca
    33241 aatgacaaac caatagagaa catcactatt aatgctattg acattgttaa ggattactcc
    33301 tttaaaaaat agcctctaag ctacaacaac aataaaacga ccagctcctt atcggaaaag
    33361 ccaccgattc aagagctggt cgtgattttt tgctatcaat taaataaaga agctagccta
    33421 ttgatcatat cattagcagc tatccattca cagccagcta tggtttacta ggaatgcttt
    33481 ttaaagtagc cctgcttagg cgaaacaaag aagctaatca gaaacaccac agccgaggtc
    33541 aaaacaatgc ttgagcctgc tgcaatatta aaggtgtagc ccaaatagag ccccaacaca
    33601 gaggtcatag ctcccaagca tgaggagata accagcatta cctttaggct gttagcatac
    33661 aaatacgctg tagccgctgg cgtaatcagc atcgccacaa tcaaaatggt accaacactt
    33721 tgcatagcag tcaccgaaac caaggtcaac aaaatcatca acagataatg ataagcagtg
    33781 accttcattc ccatagacct tgctagcaca ggatcaaagg aggtaatgag taattcctta
    33841 aagaagagga caataatagc caaaacaaaa accgaaacaa tgatcgtaat ccatttgtca
    33901 ctgtcttgca ctgctaggat atttccaaag aggatatgaa aaagatccgt tgagctatta
    33961 gcaatcccaa tcagaataac ccctaaggca agaaaagagc taaaggttat ccctattgct
    34021 gtgtctccct tgataacaga gttttccttg atgtaggtaa tgataacaga ggctagcaag
    34081 ccaaagacaa tagcccctac aaaaaaatta atccctaaaa taaaggacaa ggctactcct
    34141 ggcaaaacag cgtgagaaat cgcatcaccc attaatgaca tggacctaag gataataaag
    34201 cagcctactg ctcctgatac aataccaata acaacggctg taataagggc attttgtaaa
    34261 aaatgatagg acatcaggcc ctcaaaaaac ttcaaataca tttaaaacat tccctttcct
    34321 aagaatagat gatcaccata ggcctttgat agggtttcaa cagtgaacac ctcatcaaca
    34381 gatccataag cgatcagctc tttgttcaat accactaact catcaaagta atgctctacc
    34441 ttgcttaaat cgtgatgaac aattaaaatc gttttgcctg cttttttcaa gtccttgagc
    34501 aggtcaatga tgattttttc actaaccgaa tcaatcccaa caaagggctc atcaagaaaa
    34561 atatagtctg actcctgaat caagcatcta gctactagca tacgctgaaa ctgaccacca
    34621 gaaagagatt ttatcggacg attaccaaag ccagcaagcc caacctgctc tagcagctgg
    34681 tcaacctgat catattcttt ttttccgaca cgacgaaaaa gccctagcct agtgtaggtc
    34741 cctaatgaga cgcactcctt caccgtaatt ggaaagttgt agtcaatcat gctgcgctgc
    34801 tctacataag caatcgtatg ccccagcctt cgaccgtcct tttgatcaac agttacttgg
    34861 ccactataat ctaaaagatt gagcatagcc ttcatcaagg ttgattttcc tgcaccattt
    34921 ggcccgataa tcccaacgat agctggtcct ttgatttgta gtgagatatt gtctaaggct
    34981 tttacgttac cgttatagct aaccgaaaga ttttgcgtat caatcatttt ttctccttaa
    35041 tacaaacaaa gcacaacacc agaagctgct gtgctttatt gttatattat tttgctaagc
    35101 cttcagaaat tttatcaagg ttccatttca tcatggcata gtagctgtct ccatcttggc
    35161 cttttttggc tacagagtca gtaaagattt ctgcatagat cggaatacca ctgtccttag
    35221 aaacagtctc cattggacgt ctgtcaacac ttgactcaac aaaaagcgct gatggcttaa
    35281 cgtctttcaa tttttcgatc aatgatgaaa tttgatccgg agttccttct tcttcagtgt
    35341 tgatttccca gatgtaggct gatgggacac cgtaagcttt tgagaagtat ttgaagcagc
    35401 cttcacttgt gacgattagc tttttattgt cagcaatagc atcaaatttt gattttgctt
    35461 ccttatcaag cttctctagc ttctcaacgt aagcttttag gttgttttca taggtttcct
    35521 tgtttttagg gtctttagcg atcaattgct ttgcaatatt ttttgaatag ataaccccat
    35581 tttcaagatt caaccaagca tgagggtctt ccttgccttt ttcactttca ccttctaggt
    35641 aaatcacatc aataccatca gatacagcga agtagtcctt gtccttttcc ttcttagcat
    35701 tttttacaag ctttgtaaac caagcctgtc cgccgtcttc aaggttaata ccgttataga
    35761 gaataagatc ggcattgctg gtcttctcaa cgtcttctgg caatggctca tactcatgcg
    35821 gatcttgacc aatcggcaca atgctgtgca agtcaatctt gtcacctgca atatttttag
    35881 tcatgtcagc aataatggaa ttggtaacca caaccttgag cttgtcactc ttagcttcct
    35941 tgtttccacc attagagcag gcaaccagca tgaaaacagc caaaaaagca ctcaaggcga
    36001 ggctaagttt ctttttcatc agttatctcc ttaggatcta ttatttaatt aattaagtat
    36061 agttaattat gctattagca taactttttt ttaggccttt gtcaagattt ttatgaaata
    36121 atctgatata ataatcatta taaataagag aaaggctttt agacatgacg cctaataaag
    36181 aagactattt gaaatgtatt tatgaaatcg gagagcaaaa cattaaaatt tctaacaaaa
    36241 tggttgcaga gagaatgaag gtttctgcac ccgctgtgtc agaaatgatt aagaaaatga
    36301 tcgcacaagg ctggattgta aaggataaga cctgcggcta ttatctaaca gagcaagggc
    36361 agcgcttagt ggcaaatctt tatcgtaagc accgattgat ggaggttttc ttgatccatc
    36421 aactgggcta tactgctaga gaggtgcacc aagaggctga ggtactagag catactgtgt
    36481 cagatatgtt tattgatcgc ttggataaaa cccttggcta tcctactttt tgccctcatg
    36541 gagggacaat tccacgccgc cagcagccac taatcgaaat caacaaaaca acgcttaata
    36601 ctattaaaga gctgggaatt tttcgtttga gcagggtgca tgatcacttt gagcttatcc
    36661 agtacctaga agcacaccag ctgacgatca atagtgagtt tagactgatt caaatagatg
    36721 acttcgcaaa aacctatacc atcacttatg cagataagga attgatcatt cctgaaaaca
    36781 tcgccaagca gctctttgtt actgctattt aaataaaaaa agacctgat
//
LOCUS       DARYLJ010000020        36429 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYLJ010000020 DARYLJ010000000
VERSION     DARYLJ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36429
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            82..155
                     /locus_tag="TU746_000875"
     tRNA            82..155
                     /locus_tag="TU746_000875"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:116..118,aa:Met,seq:cat)
     gene            180..252
                     /locus_tag="TU746_000876"
     tRNA            180..252
                     /locus_tag="TU746_000876"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:213..215,aa:Phe,seq:gaa)
     gene            258..328
                     /locus_tag="TU746_000877"
     tRNA            258..328
                     /locus_tag="TU746_000877"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:290..292,aa:Gly,seq:tcc)
     gene            358..431
                     /locus_tag="TU746_000878"
     tRNA            358..431
                     /locus_tag="TU746_000878"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Ile,seq:gat)
     gene            441..528
                     /locus_tag="TU746_000879"
     tRNA            441..528
                     /locus_tag="TU746_000879"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:475..477,aa:Ser,seq:gct)
     gene            587..1402
                     /locus_tag="TU746_000880"
     CDS             587..1402
                     /locus_tag="TU746_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL0891238.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            1405..1908
                     /gene="mreD"
                     /locus_tag="TU746_000881"
     CDS             1405..1908
                     /gene="mreD"
                     /locus_tag="TU746_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL0891239.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            2004..3182
                     /locus_tag="TU746_000882"
     CDS             2004..3182
                     /locus_tag="TU746_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0891240.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            3287..4249
                     /locus_tag="TU746_000883"
     CDS             3287..4249
                     /locus_tag="TU746_000883"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL0891241.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            4609..5379
                     /gene="recO"
                     /locus_tag="TU746_000884"
     CDS             4609..5379
                     /gene="recO"
                     /locus_tag="TU746_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL0891242.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            5495..6502
                     /gene="plsX"
                     /locus_tag="TU746_000885"
     CDS             5495..6502
                     /gene="plsX"
                     /locus_tag="TU746_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL0891243.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            6495..6743
                     /locus_tag="TU746_000886"
     CDS             6495..6743
                     /locus_tag="TU746_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL0891244.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            6893..7603
                     /locus_tag="TU746_000887"
     CDS             6893..7603
                     /locus_tag="TU746_000887"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL0891245.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            7782..11522
                     /locus_tag="TU746_000888"
     CDS             7782..11522
                     /locus_tag="TU746_000888"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL0891246.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAEDLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            11641..13098
                     /locus_tag="TU746_000889"
     CDS             11641..13098
                     /locus_tag="TU746_000889"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL0891247.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            13155..14177
                     /locus_tag="TU746_000890"
     CDS             13155..14177
                     /locus_tag="TU746_000890"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL0891248.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            14174..14731
                     /gene="purN"
                     /locus_tag="TU746_000891"
     CDS             14174..14731
                     /gene="purN"
                     /locus_tag="TU746_000891"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL0891249.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            14878..16425
                     /gene="purH"
                     /locus_tag="TU746_000892"
     CDS             14878..16425
                     /gene="purH"
                     /locus_tag="TU746_000892"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL0891250.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(16803..17957)
                     /locus_tag="TU746_000893"
     CDS             complement(16803..17957)
                     /locus_tag="TU746_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL0891251.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            18348..19610
                     /gene="purD"
                     /locus_tag="TU746_000894"
     CDS             18348..19610
                     /gene="purD"
                     /locus_tag="TU746_000894"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL0891252.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            19839..20327
                     /gene="purE"
                     /locus_tag="TU746_000895"
     CDS             19839..20327
                     /gene="purE"
                     /locus_tag="TU746_000895"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL0891253.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            20314..21387
                     /gene="purK"
                     /locus_tag="TU746_000896"
     CDS             20314..21387
                     /gene="purK"
                     /locus_tag="TU746_000896"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL0891254.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            21402..21626
                     /locus_tag="TU746_000897"
     CDS             21402..21626
                     /locus_tag="TU746_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL0891255.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            22223..23515
                     /gene="purB"
                     /locus_tag="TU746_000898"
     CDS             22223..23515
                     /gene="purB"
                     /locus_tag="TU746_000898"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL0891256.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
     gene            23813..24726
                     /locus_tag="TU746_000899"
                     /pseudo
     CDS             23813..24726
                     /locus_tag="TU746_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            24809..24907
                     /locus_tag="TU746_000900"
     CDS             24809..24907
                     /locus_tag="TU746_000900"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL0891257.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
     gene            24941..25948
                     /gene="ruvB"
                     /locus_tag="TU746_000901"
     CDS             24941..25948
                     /gene="ruvB"
                     /locus_tag="TU746_000901"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL0891258.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            26189..26647
                     /locus_tag="TU746_000902"
     CDS             26189..26647
                     /locus_tag="TU746_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL0891259.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            26653..27054
                     /locus_tag="TU746_000903"
     CDS             26653..27054
                     /locus_tag="TU746_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891260.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            27051..28832
                     /locus_tag="TU746_000904"
     CDS             27051..28832
                     /locus_tag="TU746_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL0891261.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            29252..31894
                     /gene="adhE"
                     /locus_tag="TU746_000905"
                     /gene_synonym="adhC"
     CDS             29252..31894
                     /gene="adhE"
                     /locus_tag="TU746_000905"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL0891262.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            32389..33441
                     /locus_tag="TU746_000906"
     CDS             32389..33441
                     /locus_tag="TU746_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL0891263.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            33644..34660
                     /gene="adhP"
                     /locus_tag="TU746_000907"
     CDS             33644..34660
                     /gene="adhP"
                     /locus_tag="TU746_000907"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL0891264.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            35376..>36429
                     /locus_tag="TU746_000908"
     CDS             35376..>36429
                     /locus_tag="TU746_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891265.1"
                     /translation="MKEIVRSHRLLYVIVAFFSVISAFLMTLFSIQLGKILDSISNSS
                     SELLFQIVVCVCTIMAWFIMIWSYSYFKSYYVKKVILDLKERLFIGYLLREFNEIDTC
                     DRYNSDFLNNVTKNIDIIQENLLVPRVAVIVDLASMVTSVVAIVLIEWRLALVFLLLS
                     IVTVFLSQIPGKLMSKATRYYSEKSNHYLAEMTSFIEGFEQIKLLNIQKWIQKIEQNT
                     TLEFEDSRQKYQYRKDLASNTGMFLSFFSQVACMVAGIFFVRNNLLTVGLLVASIQLL
                     NGVFGPLQSFLYNKNLIKSTGTILTSIQEVLDKTNFVNGYIENKTFYEGDISSISINN
                     LTYQVENRKIFTNFSFE"
BASE COUNT        10467 a         6457 c         8498 g        11007 t
ORIGIN      
        1 ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaacag cgtgcgtggg ttcgaatccc
       61 acatcctcct ttaaagatta tcgcgggatg gagcagttag gtagctcgtc gggctcataa
      121 cccgaaggtc gtaggttcaa atcctgctcc cgcaattata taaaagatat atgctggttg
      181 gctcggtagc tcagttggta gagcaatgga ttgaagctcc atgtgtcggc ggttcgattc
      241 cgtctcgcgc cattttagcg ggtgtagttt agtggtaaaa ctacagcctt ccaagctgtt
      301 gtcgcgagtt cgattctcgt cacccgcttt atagttttcc caagctatag tgtgcttggg
      361 cgcgtagctc aggtggttag agcgcacgcc tgataagcgt gaggtcggtg gttcgagtcc
      421 actcgtgccc atcattattt ggagaattac tcaagaggct gaagaggacg gtttgctaaa
      481 tcgttaggtc gggtaactgg cgcaagggtt cgaatccctt attctccgta ttgtaaaggt
      541 gattatcata ctgataatcg tttttttatt tttagaggtg attttattga aaaagcttaa
      601 cctatctcgt ctcttttttt ggttaacatc attagcttta ctggctttga ccttggttct
      661 tctttttaga gtagctattt ctccatattt atcaatgatt atccgaaatc ccgttacaaa
      721 aattgatgct ataatgtcta agccttttgc tgttataaag gagggtgcaa aggaattaga
      781 tagcttgatg tctgcttttt ctgaaaataa gcatttaaaa aaggaactta ggtcctataa
      841 attggatcag ttacaggttg acaagctaaa atctgaaaat cgagagctca aggaactgtt
      901 agggttggat tatggtactg ataatcaatt tgctgccaga atgatatcaa gaaatcctta
      961 tagctggaat aaatcgctgg tcattgatag cggcaaaagg gaaattaagg agaagtcttt
     1021 ggttacttca gagcttggac ttattggtcg tgttacagct gttagccagt catctgctca
     1081 tgttgaattg ttaacatctg ggaagaatat tgagttgccg attaaaattg tagataagga
     1141 taaggtgatt tatggcaatt taaaggcatt taaatcagaa agtaaaacaa tggttgccag
     1201 cgaatttaat tctaatgact caatatcatt agatgctaag gtttatacaa gtggattaga
     1261 tggtgagact gtggcagata ttcctgttgg aaaggttacg ggctttaaaa atgctgctga
     1321 taagctaaag cgtcgtattt ttataaaatt gtatgctgat actgataatc ttgactatgt
     1381 tcttgttgtt ggaaaagagt gaatatgaaa aaatcttcag agctattagt ccttttgcct
     1441 tttcttttat tttttgttga tgcacacgtg tcagacctga tcagctcaat gttacctgag
     1501 ggttactcgg tagtatcaca cctcttttta ctgtttttcc tgatccttat ggtagcgttt
     1561 agatctaagg gagttatttg tttcttctct cttcttttag gattattgtt tgattattat
     1621 tattttgatc atatagggat tttgtctctt gccttgcctt ttggaacaat gatcgttcta
     1681 gggctattaa ggttcttttc tggttccatt agtcagctac aatttttcct tttctttact
     1741 ctttatatgt ttcttgtaga tgtatcaagc tttattttgg caaacagcta tcagttaact
     1801 gatatgactt ttccttatgt aatgacgttt cagcttgctc cgactttaat cgtcaatctc
     1861 cttattttgt tttgctttag aaaattaata ttaagtcaat tttattgatt attacataca
     1921 actgtaacag atgcgtaaca ttaaacgctt gattttttga tagaatataa tgtgtcttat
     1981 cgaaaaggag taattttttt agtatgaaaa aaagaattct atcagcggtt cttgtaagcg
     2041 gtgtgaccct tggaacagca actacagtgg gagcggatga tttagattcc aaaatagcgt
     2101 tgcaaaattc agttatttct aatttaaata aagaacaaaa agctgcgcag gatagaatga
     2161 agactttgca aagtcaggtt agctcattac aatctgaaca agaaaggtta gtcgctaaaa
     2221 atggtgagct tgaagcgcga tctgctcagt ttgagcagga gattcaagtg cttgccagtc
     2281 aaattattgc tcgtaatgaa aagttaaaag gacaggctcg tagtgctcaa aagggaaata
     2341 cgttaggtta cctcaatgca cttttgaatt ctaagtcaat ttctgacgtt attactcgtt
     2401 tggttgctat taatagagct gtgtcagcca atgcacagat gttggaaaag caaaaggctg
     2461 ataagctttc tcttgaagaa aagcaacagg aaaatcaaga agcgattaat acaattgctt
     2521 caaatattac agcaattgaa tcaaaccaag tagctttaaa gactcaacaa gcagatttag
     2581 aggttgccaa ggtagatttg gcgcttcaat tagcaactgc tgaggacgag aaggctagct
     2641 tgattacccg taaagaggct gcagagcagg cagcagctca agccaaggct caggcagagc
     2701 aggaagcagc agccagagca gcacaggctc aagctcaagc acagtctgta gcggcagctc
     2761 aagcagcagt gactcaagcc gtaccaacac cagctccagc gcaggcacag cctgttgtgg
     2821 cgccagcagc tatggtttca acaccagcgg tgtcgtatgc ctatgatcct tctaatccgt
     2881 accctgtcgg ccaatgtact tggggagtta aggctttagc tccttgggtt ggcaattatt
     2941 ggggaaatgg tggtcaatgg gcatcaagtg cagcggcagc aggtttccgt gtaggtgcaa
     3001 caccaatggt tggctctgtt gttgtatgga atgatggtgg ctatggtcac gttgcctacg
     3061 taacaggtgt tcagggtgga cagattcaag ttatggaagc caactatgct ggaaatcaat
     3121 ctattggcaa ttatcgtggt tggtttagcc caggtgctgt atcgtatatt tatccaaatt
     3181 agaaaataag taaaggtaag aatcaggatt cttacctttt tatttccatt gaaaaattga
     3241 ttgaaaaggg ttaaaatggt ataggatcaa aactttggag gaaaaaatgt cttattctga
     3301 tttaaagctg tttgcattat cgtcaaacaa ggaattagca gaaaaagttg ctgctgcgat
     3361 gggaattcaa cttgggaagt ctacggttcg ccagttttca gatggtgaga ttcaggtcaa
     3421 tattgaggaa tcaatacgtg gacaccatgt ttttattttg cagtcaacaa gctcgcctgt
     3481 taatgataac ctaatggaaa ttttaattat ggttgatgct ttaaagcgtg ccagtgctga
     3541 gaaaatttct gtggtaatgc cttattatgg ctatgctcgt caggatcgta aggctcgttc
     3601 gcgtgagcct attacctcta aattagtcgc taatatgcta gaggtggcag gtgttgatcg
     3661 tttattgact gttgatttac atgctgcgca gattcaaggc ttctttgata ttcctgttga
     3721 tcatctcatg ggagcacctt taattgctga ttattttgat cgtcatggtc tagtaggtga
     3781 tgacgttgtt gttgttagcc cagatcatgg tggtgtgacg cgtgctcgta agctggcaca
     3841 attcctccaa acgccaattg ctattattga taagcgtcgt agtgttgata aaatgaatac
     3901 cagtgaggtg atgaatatca ttggtagtgt tgaaggtaaa aaatgtattc tgattgatga
     3961 tatgattgat actgctggta ccatctgtca tgccgctgat gcgcttgctg aagcaggagc
     4021 aacagcagtt tacgcatcat gtactcaccc agtgctgtca ggaccagctc ttgataatat
     4081 tcaaaaatca gcgattgaaa aattgattgt tttggatacg atctatttac cagaagaaag
     4141 actgattgat aagattgaac aaatctctat tgcagatttg attgcggaag ctatcattcg
     4201 tatccatgaa aaacgtccat tgtcacccct atttgaatta gggaaatgat aaggttagcc
     4261 tgaggtagta agccttaggc ttttttatgt tttaaaaggc tatttgatta ccaaagcagt
     4321 gtttgattta acgccataga taggcttcac tgtcttatgg taggtgttga gctattatag
     4381 caaaaagtca tgtgtaggtg ctgtgtttaa acagctagcc tatgattcat atagttatgg
     4441 ctagtgactg ttgagcttct tattctcaga gttgttacga gccttaagta cagtgttagt
     4501 catgcaattt tcctggattt tgggtataat atagctgtat ttaaggtgtt ttaaaggtct
     4561 agtaagaaag gcattattac tagctgagaa gcttggttat ggagatatat gcgtattcag
     4621 aggtcacttg gtattgtctt gtacaataaa aactatcgtg aagatgataa gctcgtaaaa
     4681 atatttacag aagcggcggg caagcgtatg tttttcgtga aacatattgg tcgttctaaa
     4741 ctagctcctg tggtccagcc tttaacggct gctgattttc tattgaaaat caatgattcg
     4801 agcctttctt atatagagga ttataatcag gtggaggctt atcggcacat caatgaagat
     4861 ttttttaggc tatcctatgc tagttatgtc ttggctctgg ctgatgcggc tattccagat
     4921 aatgagcctg atcctcagtt gtttgctttt ttgaaaaaga ctcttgatct gatggaagaa
     4981 gggctagatt atgacatttt aacgaatatc tttgaagtcc agattttgga tcgttttggg
     5041 gtgagaatga attttcatga ttgtgttttt tgtcacagaa ccaatctgcc ttttgatttt
     5101 tctcataagt attcaggtgt cctttgtccg cagcattacc atgaggatga gaggcgatat
     5161 ggcttggatc ccaatgtgat ttatttgctt aatcgttttc aaacgcttaa tattgatgag
     5221 ctaaagacta tttctgtgaa tactggtatg aaaaaaaagc ttcgtctttt tattgatgcc
     5281 ttgtatgagg attatgtcgg tattcgtcta aaaagtaagg tttttattga tgatttggct
     5341 aagtggggag atattatgaa aaacaagcag ggcttgtgag ctattcaggt gtggatttgt
     5401 ccttttatgg gaattgtctg gggaatatgc tataatagtt acgttattct ctaggatatt
     5461 tttcgttaag aaaaatagga ttaaaggagc aaaaatgaag aaaattgcaa tagacgctat
     5521 gggtggtgat tatgccccta aagctattgt tgagggtgtt aatcaggcga tagaatcctt
     5581 ttcagatatt gaaattcagc tttatggcga tcaatcaagg attgagtctt acctagttaa
     5641 atcagatcgt gtgtccattg ttcatacaga tgaaaaaatt aattctgatg atgagccagc
     5701 aaaggctatt cgtcgtaaga agaatgcttc tatggtttta gctgcaaggg cagttaagga
     5761 tggtcgggct gatgcagttc tttcggcagg taatacaggc gccttgttag ctgctggttt
     5821 gtttattatt ggtcgtatca agggagtgga tcgtcctggt ttgctgtcaa ctctgccaac
     5881 ggttgatggt tcaggctttg acatgttaga tttgggtgcc aatgctgaaa acacagcaga
     5941 gcatttacac caatatgcta ttttaggctc tttttatgca aaacatgtgc gtggtattgc
     6001 caagcctcgg attggcttgc ttaataatgg tactgaggca actaagggtg attctcttcg
     6061 caaggaggtc tataattttt tagcttcaga cagcagccta cagtttattg ggaatgttga
     6121 ggcaagagat ttgatgtctg gcgtggcaga tgttgtggta gcagatggct ttacaggaaa
     6181 tgctgttttg aagtcgattg aaggcactgc tatgagtatt atgggacaat tgaaatcagc
     6241 tatagcagta ggtggtgtta aggcaaagtt tggagctctt ttattgaaga gtagccttta
     6301 tgacttaaag gatactttag attattccag tgcgggtggg gctgtattgt ttggtcttaa
     6361 agcacctctt gtgaaatcac atggttctag tgatgccaag gctatttttc ataccattaa
     6421 gcaggttcgt acgatgctag aaacagatgt agttggccaa ttagttgagg agttttctaa
     6481 ggagagtgat gtaaatgact gaggaagtta ttttagagaa aatcatcgca ttaatcaaga
     6541 agcaaagaag tcgtatagac tttgacatta cagaaaaaac agcactaaag gatgatttag
     6601 gagtagattc gattgaactg gtagagtttg ttattaatat cgaagatgaa tttggtattg
     6661 atattcctga tgaagatgtt gatggcatgg tatctatggg agatatgcta aattatttgg
     6721 tcaagcgttt aaaccaaagc taaatagttt taaaagagca ccagctcttt ttttgtttcc
     6781 gaaaaaacga acattataag tttattttat attaaatgta aataaatgtt gaatatttag
     6841 tatgtttgtg gtattgttta gatattaaat gcaaagaaag gcgaacaaat aagtgtctaa
     6901 tcaactcatt tattcaggta aggcaaagga tatctatgaa acagccgatg acgggattgt
     6961 cttaatctcc tacaaggatc aggtcactat gctaaatgga gcacataagg aaatgattga
     7021 aggaaaaggg agccttaata atcagatttc tgccttaatc tttgataggc taaatagggt
     7081 tggcgtatca actcatttta ttaagcaatt atccgagaca gaacagttaa ataaaagggt
     7141 tgcgattatt cctttggagg ttgttttacg aaacgtggcc gctggctcat tttcaaagcg
     7201 ctttggtgtt aaagaaggtc aggctttgga cgagccaatt attgagcttt attacaagaa
     7261 tgacgcttta gatgatcctt tcattaatga tgagcatgtc agctttttaa agcttgcgac
     7321 tgatgagcag atagcctaca tcaaacaaga gacgcatcgt attaatgctt atttgaagga
     7381 gtggtttgct agtgttgggt tgacactggt tgattttaag ctagaatttg gctttgataa
     7441 ggaggggatg cttatccttg ctgatgagtt ttctccggat aattgccgct tgtgggataa
     7501 tgcgggccgt cacatggata aggacgtttt tcgtcgtcag cttggcagtt tgacgcaagc
     7561 ctatgagact gttttagaaa ggctaagagc attggatcaa taaagaccag cttatttgtt
     7621 gtcagttaag aaagggagct cttttttgtc cgtcatgtaa gaaaataaat cagttcagac
     7681 tatttgagct gctgtctaag aaaggctgtc tgctattgga gaaaagagtc aggctagttc
     7741 ttattttggg ctggtttctg attggacttg gtatattaac tatgaataaa cgtatttttg
     7801 ttgaaaagaa ggctgatttt cagattaagg cacaggtcct gttaaaggaa ttgaaacatc
     7861 agctgcagtt aaagacactg gttgatttgc gtattgtgca ggtttatgat gtgtttcatt
     7921 tggatcagga gctgctttta acagctataa agcatgtttt ctctgagcag gtcactgatc
     7981 aggtattgtc agaagaagct ttacaagcag atttaaaaag gtatgccttt tttgcgattg
     8041 aagctctgcc tggacagttt gatcagcgtg cggcaagctc tcaggaagcc ttattgttgt
     8101 taggagcctc aactgatgtg actgttttga cctcacagct ttatttggtc aatcaagaca
     8161 ttgctgctga agaattagaa gccttaaagc agtacttgtt aaatccagtg gattctaggt
     8221 ttaaggacat attagccggt cttgatgatc aggatttttc agtagcagat aaagtgattc
     8281 caacgcttga tgtttttaat gattatacag cggaagatct tgctcgttac aggtctgagc
     8341 agggcctagc aatggaagtg gaggatctgc tgtttattca ggattatttc aagacaaagg
     8401 ggcgagtgcc aacagagact gaactaaggg ttttggatac gtattggtct gatcattgtc
     8461 gtcacacaac ctttgaaaca gagctaaaaa cgcttgattt ttcagcttct cattttgaaa
     8521 agcagctcca agctacctat gagacctacc ttgctatgcg tgatgagcta ggtcgatctg
     8581 aaaggcctca aacgcttatg gatatggcta ccatttttgg acgttatgaa agagctaatg
     8641 gtcgtttaga ggatttggag gtttcagatg aaatcaatgc ttactcagtg gaaattgagg
     8701 tagatgttga tggtgtcaag gagccttggc tgctcatgtt taaaaatgaa acacataatc
     8761 acccaacgga aattgaaccc tttgggggtg ctgcaacctg tattggtgga gctattcgtg
     8821 atcctctgtc aggccgttcc tatgtttatc aagccatgcg gctttctggt gcaggggaca
     8881 ttacaagccc gctgtcagag actcgtaagg gcaaattacc acagcaggtt atttcgaggc
     8941 aagcagcaca tggttactcg tcatatggca atcaaattgg gctagcgact acttatgttc
     9001 gtgagtattt tcacccaggc tttgttgcca aacgtatgga gcttggtgcg gtagttggtg
     9061 ctgcacccaa ggaaaatgtg gttcgtgaaa agccaaggac aggtgacgtg gtggttttgc
     9121 ttggtgggaa aacaggacgt gatggtattg gtggtgcgac aggatcatct aaggttcaga
     9181 cagttgagtc tgtagaaaca gctggtgcag aggtccaaaa aggaaatgcc attgaggagc
     9241 gtaaaatcca acgtcttttt cgtcgtggcg atgtgacacg cctcatcaag aagtcaaatg
     9301 attttggtgc tggtggtgtt tgtgtagcca ttggcgagct tgctgctggt cttaacatta
     9361 acttagataa gattccttta aaatatgctg ggctaaatgg aacagaaatt gccatttcag
     9421 aatcccaaga gcgtatggct gtcgtgattt gtccaaagga tttagaggcc tttatgagcg
     9481 cctgccataa ggaaaatatc catgctgctg ttgtggcagc tgtgacagaa aaaccgaatc
     9541 ttgttatgac ctggaatggg cagacgattg ttgatattga acgctcattt ttagagacaa
     9601 atggtgtgcg cgtgtctgtt gctgctaagg ttgttgacag tggtgcgcca ataccagaag
     9661 ctcgtcaaac tactgctgag acacttgaag cagataccat tgctgtctta tcagacctga
     9721 accatgctag tcaaaagggt ttgcaaaccc tgtttgatag ctcagtgggt cgctctacag
     9781 taatacatcc gcttggtggg cgctatcaaa tgacacctgt tgaaggctct gttcagaaat
     9841 taccagttca acatggagtg acaaagacag tctctgttat cgctcaaggc tatcaccctt
     9901 atatagccga atggtcacct tatcatggtg ctgcttatgc tgtaattgag gcaactgctc
     9961 gtctggtcgc aacgggtagc cattggcata aggcacgctt ttcatatcag gaatatttcc
    10021 aaagaatgga taagcaggca gagcgctttg gtcaaccggt ggcagccttg cttggagcaa
    10081 ttgaagcaca ggtgcagctt ggcttgcctt ctattggagg taaggattca atgtctggta
    10141 gctttgagga attgacagtg ccgccgacct tggttgcctt tggtgtgacg actgctcatg
    10201 tagatcatat cctttcacca gaatttaaag ctgctggcga gaatatttac tatattccag
    10261 gacaggctat ttcggaagtg attgattttg agttgataaa atctaatttt atgacttttg
    10321 aggctattca gaaaaagcat aatattagct cagcttcggc tgttaaatat ggtggtgttg
    10381 ttgaagcact ggctcttgct gcctttggta atcggttagg ggcttgtgtg acattaccag
    10441 agcttgacag gagcttaaca gctcagcttg gtggctttat ctttacatca aaagaggaaa
    10501 tcacaggtgt tatcaagctt ggtcaaacta ccagtgactt tacattggtt gtcaatgatg
    10561 tcaagctatc tggagctcgt ctcttaaagg cttttgaagg gagcctggag caggtttacc
    10621 cgacggtatt tcagcaggca ggtgaattga agcctgttcc tgtagtgaca acagcacttg
    10681 ctgctcagtt taaggaaaaa atagctcagc cagttgtcta tattccagtt tttccaggaa
    10741 ctaactcaga atatgattcg gctaaggcct ttgaaagaga gggtgcaagg gtgaacttgg
    10801 tgccttttgt taccttgaat gaggcagcta ttgacgcttc agttgacacg atggttgacc
    10861 atattcatca agctcatatt atcttccttg caggtggttt ttcagcggca gatgagccag
    10921 atggttcagc taaatttatt gttaatatcc tgctgaatga gaaggttcga atggcgattg
    10981 atgcctttat tgaaaagggt ggtctgatta tcggtatttg taatggcttt caagctctgg
    11041 tcaaatcagg gctgctgcca tatggacgtt ttgaggcggt acatgaggct agtccaactc
    11101 tgttttataa tgatgccaat cagcatgtgg ctaaaatggt agaaacgcgt attgccaata
    11161 ccaattctcc ttggctggca ggtgtcaggg tgggggatat tcatgctgtt gcagtgtcac
    11221 atggagaggg caagcttgtg gtaacagaaa gagaattagc agagctttgt aaaaatggtc
    11281 agatttttag ccagtatgtt gaccttgatg gtaatccaag catggatagc aggtataatc
    11341 caaatggctc tgtcaacgct attgaaggtc ttaccagcaa aaatggtcag attatcggta
    11401 agatgggaca ttcagagcgc tttgaagagg gacttttcca aaatattccg ggtaataagg
    11461 atcaatggtt attccgaagt gcggtgcatt attttagagg agaccatgtg ggtattgact
    11521 gaactgggat atagccttgt aatagctaag atagctgcta ttattgctca gcctagctgt
    11581 tagttctagc ttagttaatg acacaatcat aattaaaagg gcattagccc agaggtaaag
    11641 atgacatatg acgtaaaatc tcttaatgag gaatgtggtg tttttgggat ttggggacac
    11701 ccacatgccg ctcaagtgac ttattttggg cttcatagcc tacagcaccg cggccaagag
    11761 ggagcaggta ttatttcaaa tgataatggg gagcttcatc agcatcgtga tgtaggtctc
    11821 ttgtcagagg tgtttaagga ttcatctgat ctggacaagc taaagggaca tgctgccatt
    11881 ggtcatgtgc ggtatgcgac tgctgggacg gcttccatta ataatattca gcccttttta
    11941 tatcgtttta cagacgctca atttggcttg tgccacaatg gtaatttgac caatgctatg
    12001 tcattgaaaa aagcgttaga gagtgaggga gctattttta atgcctcttc tgatacagaa
    12061 attctaatgc atttgattcg tcgtagtcat cacccagaat ttttaggaaa ggtaaaagag
    12121 gcactcaaca ctgttaaagg gggctttgct tacctgctga tgacagagaa ccagctgata
    12181 gcagcgcttg atccaaacgg ctttaggccg ttgtctatag gccgtatgaa aaatggggct
    12241 tgggtcgtct caagtgagac ctgtgccttt gaagtggttg gtgctgagtg ggttcgcgat
    12301 gtgatgccag gtgaggtcat tatcattgat gatcagggga tcacttatga ctgctatacg
    12361 actactacgc agctggctat ctgctctatg gaatatattt actttgcgcg tcctgattca
    12421 accattgctg gagtcaatgt tcacaccgct cgcaagcgaa tgggaaagag actggctcag
    12481 gaatttcagc atgaggctga tattgtggtt ggtgtgccaa attcctcatt atcagcagcg
    12541 atgggctttg cagaagcatc aggcctgcca aatgaaatgg gattggtcaa gaatcaatat
    12601 acccaacgaa cctttatcca accaactcag gagcttcgtg agcagggagt tcgaatgaaa
    12661 ctttcagctg tttcaggtgt tgtcaagggc aaaagggttg tgatggtaga tgattctatt
    12721 gtcagaggga caacctcacg acgcattgtt aatttgctgc gtgaagcagg agctacagag
    12781 gttcatgtag caattggtag ccctgagctc aaataccctt gcttttatgg gattgatatt
    12841 cagacaagac gggagctgat ttcagctaat catactgctg ctgaggtctg tgatattatc
    12901 ggtgctgata gcctgactta tttgtcactt gatgggctta tcgaggctat tggacttgat
    12961 acaaaagcac caaatggtgg gctttgtgtg gcttattttg acggtcagta tccaacgccg
    13021 ctttatgatt atgaggaggc ttatctcaag agcttagaag aaaaggtaag ctttcacatt
    13081 gatcaggtga cgaagtagcg ctttatggct aacatagaat aaatgatcta ggcagctaaa
    13141 ataaggagga gaaaatgtct aaaaatgctt atgctcaatc aggtgtcgat gttgaagcag
    13201 gctatgagct tgttgagcga ataaaaaagc atgccgagcg tagcaaacga ttgggtgtta
    13261 tgggtggtct aggaggcttt ggtggtctgt ttgacctgtc aaagactggt gttaaggagc
    13321 ctgttttggt ttcagggaca gatggcgtcg gaacaaagct aatgcttgca atccagtacg
    13381 ataagcatga cacgattggg caggattgtg tggcaatgtg tgtcaatgat attattgcag
    13441 caggtgccga acccctgtat tttcttgatt accttgcagc aggaaaaaat gagcctgcca
    13501 aattagagca ggtgattgca ggtattgctg agggctgtgt tcaagcaggt gctgctctta
    13561 tcggtggaga aactgctgag atgcctggta tgtatggtca agatgactat gatcttgccg
    13621 gttttgcggt tggtattgct gagaaatctc agctgattga tggttcaaga gtagctgagg
    13681 gagatcatct cctaggtttg gcatcaagtg gagttcattc aaatggttat tccttggttc
    13741 gtcgtatttt tgccggttat actggtgagg agctgcttcc agagcttgat ggaaaaaagc
    13801 ttaaggaggt acttcttgag ccaactcgta tttatgtcaa ggctgtgtta ccactcatta
    13861 aaagcggctt agtggcagga atcgctcata ttacgggtgg cggctttatt gaaaacctac
    13921 ctcgtatgtt ttccaaagaa ctagccgctg aaattgaaga agccagctta cctgtgctgc
    13981 ccatttttaa agtccttgag acatatggta agatcaatca tgaagaaatg tttgagattt
    14041 ttaatatggg tattggcatg gtgcttgctg tcaagcctga gcacgttgag caggtgaagg
    14101 cctgtcttga tgagcctgtg tatgacattg gtcgcgttgt gaccagaaca gttgctagtg
    14161 tggtgatgaa gccatgacaa gaattgccgt ttttgcttct ggtaatggct ccaattttca
    14221 aacgattgca gaacagtttc cggttgcctt tgttttttct gatcattgcg atgctcatgt
    14281 tttaagtaga gcctgtgctt tgggtgttct gtcctacagc tttgaactaa aggactttga
    14341 gaataagcaa gcctatgagc agactcttgt ggcattgctg cagcggcatc agattgatct
    14401 catcgtcctt gccggctata tgaaaattgt gagtacaacc ttacttgatg cttacgaagg
    14461 aaaaatcatc aacattcacc cagcttattt gccagaattt ccaggagcac atggtatttt
    14521 agatgcttgg caagcaggtg ttagtcagtc aggagtgact gttcattggg ttgatagtgg
    14581 tattgataca ggaaaaatca tcaaacaggt acgagtacca cgtttgagtg atgatactct
    14641 tgaaagcttt gaagccagaa ttcatgaagc agaataccaa ttgtatccag aggtactgga
    14701 tagtcttgga gtagagcggc ttaaccgctg attgtgtaag attaataact attttcccta
    14761 ttgtggcatt tcgtttatca tagcagctgc gctaatggtg gctaacaaag gctagaagac
    14821 ttgtttgatg atggcactgc tattgaggaa aatagacttt tctaaggaga acttaaaatg
    14881 actaaacgcg ccttaattag cgtatcagat aaaagaggga ttgtggacct tgctagggag
    14941 cttaagcatc ttggctggga tattatatca acaggaggaa caaggcttgc tcttgaagag
    15001 gctggtgtag ttactgttgc tattgacgat gtgacaggct ttcctgaaat gatggacgga
    15061 cgggtaaaaa cgctgcaccc tctcattcat ggtggcttac ttgctcgtcg tgacattgag
    15121 caccacttac aggcagcaaa gcaaaacagg attgaattaa tagaccttgt tgttgttaac
    15181 ctttatccct tcaaagaaac catttgccgt ccagatgtca cttatgatgt cgctgttgat
    15241 atggttgata ttggtggtcc ttcactgctg cgttcagcgg ctaaaaatca tgctagtgtt
    15301 acggtagtgg ttgatccgac agattatccg ctcgttttag gagagttggc tagcactggc
    15361 agtacaagtt accaaacccg tcaaagctta gcagctaaag cttttcgcca tactgcagcc
    15421 tatgatgcag tgattgcaga ttattttaca agacaagcag gtgagacaaa gcctgaaaag
    15481 ctcacgctta cctatgattt gaagcaaagc atgcgttacg gtgaaaatcc tcaacaggct
    15541 gcagattttt accaaagagc gctcccaaca acctattcaa ttgcttcagc caagcagcta
    15601 aatggaaaag agctatcatt caacaatatt cgtgatgcag atgctgcgat tcgtattatt
    15661 cgtgatttta aggagcgtcc aaccgttgta gcactcaagc atatgaatcc atgtggtatt
    15721 ggtcaggcag atgatattga gacagcttgg gattttgctt atgcagctga tccggtgtct
    15781 atctttggtg gtattgttgt cctaaatcgt gaggtggatc tagcgacagc ggagaagctt
    15841 catgctattt ttcttgaatt gatcattgca ccaggctatt ccaaagaagc gctagctgtt
    15901 ctcacccata aaaagaagca cttgcgaatt cttgaattgc catttgctgc tcaggaggct
    15961 agtgaaatag aagcagaata tacaggagtt cttggtggtc tactagtgca aaatcaagat
    16021 gttgtcacag agtctccagc ggattggata gtggtgacaa agcgtcagcc aaatgaacag
    16081 gaaatggctg ctctagcatt tgcttggaaa accatcaaat atgtcaagtc taatgcgatt
    16141 gtcattgcta atgatcatat gactttgggc gttggtccag ggcaaacaaa ccgaatagcc
    16201 tctattcgta ttgctattgc gcaagcaacg gggcagcttg agggagcagt tcttgctagc
    16261 gatgccttct tcccatttgc agacagcatt gaagaaattg ctgccgctgg tatcaaggct
    16321 attatccagc ctggaggctc tattcgtgat tcagaatcta ttgcagctgc caatcagcat
    16381 ggtataacca tgattttcac aggtgtgagg cattttagac attaataaag taaaaagaga
    16441 ctggagccaa aagagttgca ctttagaaat tcttggttaa tatactttat tacctagttg
    16501 gattcattaa aaagcgaaca agtctagttt tcataatctc agaaaactag acttgtttgc
    16561 ttgttttatt tggtggtcat actattgttt cagcctcttt ttactatgac taatacaaga
    16621 atttatgaag gaacaaggct ttattttttg ttgtggtaac agtgaccaga tccgttatca
    16681 atcagtattt gagtattttg agctctagat gcatcactta gataggatat tgcaaaggat
    16741 acagctgctg catgtattag gaaagcatta tcataaaagg ctttttcgtt agcctaaagg
    16801 ttttagacct tctttgcctt atctattgtt aaccatgttc cacgtgaacc catttgcacg
    16861 taaatcccct tgctaggctg atcaaccttt agaaccttat aggttcctga aacgacaaaa
    16921 taatcaccca cctgcaaaat ctgatttcca gcaatacgtc ctttatggtc cgtttcgtgg
    16981 agtggagctg agtctatcca gtttaaggag gttggctctc caccggctaa ttcactgctt
    17041 gcaatcatgt tctgagcgac ctgatcgacc cgaaaaacac caggaaaggc tacagtatct
    17101 ccaaccttga taggagtggt cgccacaggc tttggtttat ctatagaggc ttgactatgt
    17161 tgctgaggct gaaccggcaa tttgtgaatt ggaatgtagc gatgatttcc tgaatgaccg
    17221 atatagctga gccattcata gccatcagcg acaagggttt gatcatagtg cactaactgt
    17281 ccagtatgat agtaagctaa atcaggactt gctaatgtag cttcagcctt tataggactt
    17341 tggcttgaaa aataataggt accactttta gctagacgag ttgatcctgc ttgagaagca
    17401 tgtaacattt gtgtgtggct ggtagagttg tgatccagat ccttgaagtg aatgtaacca
    17461 cttacctgat gcttatgaat ctgtcgttta tgatactttt caggtccctg tccggcatta
    17521 tagttgtatt cctcaataat aacagtgtca ccattgacct ctgctaccca ggcgacgtgt
    17581 ccatataggg catgtgactg gttaaagccc ttatcccacc aagcaacagc accaactcta
    17641 ggtgtatgat caacatgata gccttggtgt ttagctatac gtccccagct ttcaacatta
    17701 ccatagcctc taggcaggct gaatccattt gaggaatgca gtcggaatgc tacaaaagaa
    17761 gtgcattgac gtaagtacat gttccaagga tcagctccga agccctgttt ccacttactt
    17821 ggatagttat cccctaaaac agcagcgtgt acgatacctg actgaccttg tgaaatcgtt
    17881 gttgtggcag aggatattgc accattacca cctaaaagga ttgctcctga agctaacaat
    17941 tgatagactt ttttcattaa ttacctcctg taacttacta ttcgcaagaa agaggacaaa
    18001 aatgtccttg atttaaaaaa atgtaaggaa aaatatttta gcctcaaaat actgttggtg
    18061 ctccctagct tccaagagcc aataggcaag cccatctcca gcttgcctgc tccctgtagc
    18121 taaaagcaat ttatagtaac actagcacct catctgaaga ggcaggctgt ggtaattaat
    18181 gccaataatc tgtaaaaaga gacagcaggt atggttatat gagctatgat ggttatattc
    18241 tataaagctt attttttagc ttcgggcttt ctttggtgat tagttattta tataaacgaa
    18301 caattatgct aaaatatgtt tataaaattc gtgttatgag gtgtgtgatg aagcttttag
    18361 ttatcggttc aggtggtcgt gaacatgcga ttgctaagaa attgttagag tcaaaaggcg
    18421 ttgaacaggt ttttgtggca cctggcaatg atggcatgac ccttgatggc atagaacggg
    18481 tagatattga catttccgaa cattctgctt tgattgcttt tgcaaagacc aatcatatag
    18541 cctggacctt tgtgggacca gatgacgcat tagcggctgg tatcgttgat gagtttaacc
    18601 agtctggctt gaaagccttt gggccctctc gtttagcagc ggagctggag tggtcaaagg
    18661 actttgctaa gcaaatcatg gtcaaatacg gtattccaac agcagcctat ggcacatttt
    18721 ctgattttgc aaaagccaag gcctacatcg aggaaaaggg cgcgccaatt gtggttaaag
    18781 cagatggttt ggcgctagga aagggtgttg tcgtagcaga gactgtagag caggcagttg
    18841 aggcggcgcg tgacatgctc ttggataata aatttggtga ttcaggtgcg cgcgtggtga
    18901 ttgaggaatt tttagctggt gaagagttct ctctctttgc ctttgtgaat ggcgatcagt
    18961 tttacctcat gccgacagcg caggaccaca agcgggctct tgatggtgac aaggggccaa
    19021 atacaggtgg tatgggggct tatgcaccag tgcctcatct ttctcaaagt gtggtggata
    19081 cagcagttga gaccattgtc aagcctgttc taaaagggat gatgacagag gggcgtccct
    19141 atcttggaat cctttactgt ggcttgattt tgacagaaga tggaccaaaa gtgattgaat
    19201 tcaatgctcg ctttggtgat cctgagactc aggttatcct tcctcgcctg acctctgatt
    19261 ttgcacagaa cattaccgat atattagagg gcaacacagc taatatcaca tggtcagacg
    19321 agggagtgac gctcggcgtt gtccttgctt caaacggtta tccgcttgct tacaagaaag
    19381 gtgtgcttct gccagcaaag accactggcg acatcattac ctactacgca ggggttaagc
    19441 ttgcggaaaa tggcaaagca ctgctgtcaa atggtggacg tgtctatatg ctggtcacca
    19501 cagcagttac cgtcccagct gcgcaagaaa aaatctatac cgaacttgct cagcaaaata
    19561 ccgaaggatt attctaccga aacgatattg gaagaaaagc agtaaaataa attagcgcta
    19621 gctcaagcta ccgaaggtcg ctatgatgac aatgacttat tatcggtgag caaaagcgag
    19681 cctaacacga tacttttcgc cgtagcgcaa agagtgacaa ggtcactcgg gggaacttga
    19741 aagaccttgg gctttcaagt tagtcatgag acacctatgg tggctgttga cgcccccccc
    19801 cacttaagaa aagtatcaaa aacctttaag gagaaagtat gaaaccaatt atctctatca
    19861 tcatgggctc caaatctgac tggaccacca tgcaaaaaac cgccgaaatc ctcgaccagt
    19921 ttggccttgc ctacgaaaaa aaagtggtct ctgcccaccg cacgccggat ctcatgttca
    19981 catacgctga gaaagcacgc gaacgtggca ttaaaatcat catcgctggt gctggcggag
    20041 cagcccatct ccctggaatg gtcgctgcaa agacgacact tcctgttatc ggcgtacctg
    20101 tcaaatcgcg tgctcttagt ggtcttgatt cgctgtattc aattgtgcag atgccaggtg
    20161 gtgtgcctgt ggcaactatg gccattggag aggcaggagc aaccaatgca gcactgactg
    20221 ctcttcggat cctttcaatt gaggatgaaa caatcgcaga gcagctcagc catttccaca
    20281 aagagcaagg acggatcgca gaggagtcaa cccatgaact caactaaaac aattggaatt
    20341 atcggaggtg gtcagctggg acagatgatg gcgatttctg ccatttatat ggggcataag
    20401 gtcattacac tggatccagc agcggattgc ccagcctcgc gcgtgagtga ggttatcgtg
    20461 gcgccttata gtgatgtgga ggcgctgcgt caattgaccg agcgctgtga tattttgacc
    20521 tatgaatttg aaaatgtgga cgctgacgcc cttgatacag tggtaaagga ggagcagctg
    20581 cctcaaggaa cagagttact tcggatctcg cagaatcgta tttttgaaaa agatttttta
    20641 gccaataaag caagcgcggc agtggcaccc tacaaggttg taacctctag cctcgacttg
    20701 gaaaaccttg acttttcgaa aaaatacgtc ctcaagacag cgacaggtgg ctatgatgga
    20761 cacggtcaag tcgttattcg ctccgaagca gaccttgaag aggctaataa gttggctaac
    20821 actgccgagt gcgtcttgga agaatttgtc agctttgacc gagagatttc cgttattgta
    20881 tctggcaatg gcacagatgt cactgtcttt cctgttcagg aaaatatcca tcggaacaat
    20941 atcctgtcaa aaaccattgt cccagctcgc atttcagaag cagttagcgc taaatcgcag
    21001 gctatggcgg tgaaaatagc agagcagctt aacctatctg gcaccctctg tgtagaaatg
    21061 tttgtggcag gcgacgagat tttggtcaat gaaatcgccc cacgtcccca caactcagga
    21121 cattactcca tcgaagcctg tgatttctcc cagtttgaca cccacatttt aggtgtatta
    21181 ggccagccat taccagctgt caaactccat gccccagcca ttatgctcaa cgtcctcggc
    21241 cagcacatgg aacaagccca acgctacgcc acagaaaacc ctagcgccca cctccacctc
    21301 tatggtaaaa tagaagccaa gcacaaccgc aaaatgggac acgtgacggt gtttaacagt
    21361 caatcagatg aggttgaaga attttaggag gaattaatcc tatgataaaa atcattgttc
    21421 acgcttttat tgaaaatggt gaaacaggtg ttgttgaagt tgtctttgct tcggaaaacc
    21481 aagaatccat ttctgaaaaa atgacggagc tacaaaagca atatccaaac gattaccttg
    21541 ctatctatga tttaccacta gatacagacc tatcgcaatt ggcccactat ccgtcaatag
    21601 cgataggcaa aggggagttt gagtagttaa ggaagattag tatttcggat tgagtgttat
    21661 tgggacaatt tatggctatg cctttcaaaa gattggtcat gatgttgagc atgttgtgag
    21721 aattgagaat cgtaatcaga tttcagaagt tggtaaatga cttaatggat aattctagat
    21781 actgatctcg agcaatcata agagaaatgt tgaaattgta gcttctggag gtgtagaact
    21841 caaaaattat cgtggtgaga tatttccata taaaacttct aagcgtattt cgtctagatt
    21901 gataacatat agataggttt gtacataatg aacttactag atgcatcatg acaaagcaga
    21961 tcttttatat acatgcaaag aggtttacaa tattggtata gtcaactatt gatgccctaa
    22021 cttttaatca caatatagaa attattgcga atagacttta aaagcattac tattaactat
    22081 gtagaaagga aatgagcgct agaattttca aactgaacct gagcggaaag ctcggaattt
    22141 agataaattt cctcggacgt aaatgtccgt ctttagcttt ctaaaattca gttgctttct
    22201 ggctgttctt ggtatcttaa ttatgctaaa ccgttattca cgccctgaga tggcgaagat
    22261 ttggagtgaa gagaacaagt accgtgcttg gttggaggtg gaaatcctcg ctgatgaggc
    22321 atgggctgag ttgggtgaga ttcccaagga agatgtggcg aagattcgcg ccaatgcgag
    22381 ttttgacatc aatcgtattt tggagattga agaagagacc cgtcacgatg tggtggcctt
    22441 tactcgtgcg gtgtctgaaa cgctcggtga ggagcgcaag tgggtccact atggcttgac
    22501 atcgactgac gtggtggata cggcctatgg ctatctctac aagcaggcta atgacattat
    22561 ccgtcgtgac cttgaaaact ttaccaacat tgtggctgag aaggctaagg agcacaaaat
    22621 gactatcatg atggggcgta ctcatggtgt gcacgcggag ccaacgacct tcggtctcaa
    22681 attggcgacc tggtacagtg aaatgaagcg taatcaagag cgttttgagc atgcggctgc
    22741 tggtgttgag gccggtaaaa tctcaggtgc tgttggaaac tttgccaata tcccaccatt
    22801 tgttgaggag tatgtctgtg gcaagctagg cattcgcccg caggaaatct caactcaggt
    22861 cttgccacga gaccttcatg ccgagtactt cgcagtgctt gctagtatcg cgacatcaat
    22921 tgaacgcatg gcaactgaaa ttcgaggcct gcaaaaatct gagcaacgtg aggtagaaga
    22981 gttctttgcc aaaggacaaa agggaagctc tgccatgcct cataagcgta acccgatcgg
    23041 ctctgaaaac atgacggggc ttgcgcgtgt cattcgtggg cacatggtga cagcctatga
    23101 gaacgtggcg ctttggcatg agcgtgatat ttcgcactcg tcagcagagc ggattatcac
    23161 accagacacg actatcctca tcaactacat gctcaaccgt tttggcaata tcgtcaaaaa
    23221 tttgacagtc tttccagaaa acatgactcg taacatgaac tctacctttg gcttgattta
    23281 cagccaacgt gtgatgctta agctgatcga aaaaggcatg acgcgtgagg aggcgtatga
    23341 cttggtacag ccaaagacag cctattcatg ggacaaccaa gtggacttca agccgatcct
    23401 tgaggcagac gaaaatatca ctgcaaaatt aaggcaagat gagcttgatg agctcttcaa
    23461 tccagcttat tataccaagc gtgtcgatgc tattttcgac cgattaggat tataggaaga
    23521 aaacagcgcg tctttttaga ctgtagctaa gcccagattt gtttaaaaag tcttgaaaat
    23581 gaattcctcg gagctaattc tcaaaatgaa gaatagtatt tcaagagagg ctgtcactag
    23641 ctatatcgct taagaaaatg ctctaaaata gacatttttt caatctgaga aggcaatagg
    23701 ccttcttttt ttctaaaaat acagaaatgt tattatagaa tggagtcaaa aaattaataa
    23761 ttaattaaat tatgtgatat aatgaaagaa atagtgtctt gaagagggaa acatgttaga
    23821 caattttggt gaaaaggtga gagaccttcg gtatcagaaa aaaattacca gagaggattt
    23881 atgtggagat gagtcagaat tatccattcg tcaattggca cgaatagaac tgggccaatc
    23941 gattcccagc ctatcaaagg tggtttttat tgctaaggct ttggacgtta gtgtcggctt
    24001 tttgacagac ggagaggatt tggagctacc gaagcgctat aggagcttaa atatttgatt
    24061 ttaagaacac cgacctatat ggacgatgac aaattaaagc tgcgagaaga gcaatttgac
    24121 gaaatttttg aagattatta tgaccagttg ccagaggaag aaaagcttgt ggtggattgc
    24181 ttgcagtcca taatggatac gttattaacc gagaatatca attttggagt tgggttatta
    24241 caggaatact ttgaacaaac aaaaagtaag actcaattta gagagaatga tctcattctt
    24301 attgagctgt atttagcgta cctcgacatt gcaggaatga atggagagta ttcagataaa
    24361 ggattctatg attctttgtt agacattttg ttaaatcagt ttgaacattt tgaattagag
    24421 gaattattta ttgtcaataa aatagctata ggaatttcct cgttgagcat caaaaacaat
    24481 aagccggaga ttcttgagaa ggttattgta cttagtcaaa aaattatcct caagactcag
    24541 gattttaata gaatgcctat cttaaatttg atagagtgga aatatgctct aatgaagaaa
    24601 aaagacatag aaatggccaa aaaatgctat gctaaggcat gcctgtttgc tcaattaaca
    24661 ggagatcagt atttggaaaa gaaattgaga gaagaatggg gtaaagatat aaaacgatat
    24721 caataggaca aaaatgtcat ttttatcaaa aatggaataa tatataatct ttatataaca
    24781 aataattgat taaaggagtt ccatttatat gtttaaaaaa taccaatact atctgttttt
    24841 agctgcttta tttctacttc attctgccca attacttagt gatattgact ggtggcgtgt
    24901 tggttaaagc taaatcatct atttatgcta taatagctct atgacaagaa ttttagataa
    24961 tgatctgata ggcgatgaag gatctgttga gaggacacta cgtccacagt atttacgtga
    25021 gtatattggt caggataggg ttaaagacca gctgatgatt tttattgagg cagccaagag
    25081 gcgtgaggaa tccttggatc atgtcctgtt atttggttcc ccaggcttgg gtaaaacaac
    25141 gatggccttt gtcattgcca atgaattggg agttcatctc aagcagacct ctggcccagc
    25201 cattgaaaaa gctggtgatt tggtggcaat tttgaatgat ttagagccag gagatgtcct
    25261 ctttattgat gaaattcatc gtatgccgat ggctgttgag gaaatcttgt acagtgccat
    25321 ggaggatttt tacattgata tcatgattgg cgctggagac actagccgga gtgtgcattt
    25381 ggagctgcct ccctttacat taattggagc aacgactcgt gcaggcatgc tgtcaaatcc
    25441 tttgagggct cgttttggga ttactgggca tatggaatat tatcagacag ctgatttaac
    25501 agagattgtg gagcgtacag ctgatatttt tgacatgaca atcaagcatg aggccgctta
    25561 tgaactggca cgcaggagtc gtggaacccc tcgtattgct aatcggctgt taaaaagggt
    25621 gcgtgattat gctcaaatta tgggtgatgg aatgattacg actcaaatca cagataaggc
    25681 tctaacgatg ttagatgtgg atcaagaagg tttagattat gtggaccaaa agattcttcg
    25741 taccatgatt gaggtgtacc aaggagggcc ggttggtctt gggactctat ctgtcaatat
    25801 agcagaggag cgagatacag tagaagacat gtacgagcct tatttaattc aaaagggttt
    25861 tatcatgcgt accagaacag gccgagttgt caccgaaaaa gcctatcagc acttaggcta
    25921 tccctatgaa aaaaccatta agacataaat agctatgtaa gacttgattc ctttgttttt
    25981 accggtgtca agtcttttgt attgtcaata gcttactgag taaaaaagta aaacgatgtg
    26041 aggtgagggg tgattggtca gggaagcaga ggtgctttca ctagacaaag cattaaaaaa
    26101 catttttaga tcaattgaac gaaaattata agagcgattt ctccttttgg ccctataatt
    26161 ttgctataat aggtaaaagg agtttttcat gaaaaaagta tgctttgttt gtcttggaaa
    26221 tatttgtcgt agtcctatgg ccgaatttgt catgaaaagt atggccagtc ctgatgagct
    26281 acaggtggag agtcgtgcaa cctctggctg ggagcatggc aatccaattc atcatgggac
    26341 acaatcgcta ttacagcaat atcagattag ctatgatacc aagaaaacct ctcagcaaat
    26401 caccagcttt gactttgaag cctttgacta tattatcgga atggatagcc ataatatcag
    26461 agatttgaag caaatgtcca agcatcagtg ggattccaag atccatcttt ttattgaagg
    26521 aggcgttccg gatccttggt atacaggaga ttttgaagaa acctaccgct tggttaaagc
    26581 gggctgtcag cattggttga gtcaaatcag cgctgaacat gaatcacatg tggaaataga
    26641 tgagtaatag taatgaaagc aataataaat aacattcaaa aatggcagat cactcggaca
    26701 aagctagaga ttatttcagt ccttgtgatt attgtctgtg gattgtcggt ttttaccttg
    26761 accatatcct caaaagcaag cttgacctat gacaatgggc aaatcaagta caccggctat
    26821 gtccttaatc atagaatgaa tggtaaaggg aaattggttt accctaatgg cgatacctat
    26881 gttggggatt ttaataaagg tgtctttgat ggagaaggaa cgtttacagc tagtacaggg
    26941 tggtcttaca gcggacaatt taaaaaaggt caggctgatg gcaagggtac tttgaaggcg
    27001 aaggattcaa aggtttacaa aggaaccttt aagcagggga tatttcaaaa atgaggataa
    27061 aatggttttc gtttattagg gtaacaggtc ttttgctggt gttgctctat cactttttta
    27121 agcatacttt ttcaggaggc tttgttggcg ttgacatctt ctttactttt tcaggctatt
    27181 tgattacagc cttgttgatt gatgaatatg tctcaaaaca aaccattgat gtggttgctt
    27241 tttttagaag gcgtttttat cgtattgtac cgccgcttgt cttgttaatt ctcttgacaa
    27301 ttccctttac ttttttagtc aaaagtgact tcattgctgg tatcggtcag caaatagcag
    27361 ctgccctagg gtttacaaca aatagttatg agctactgac aggcagtagc tatgaaagtc
    27421 aattcattcc gcatctgttt gtgcatacct ggagcttggc cattgaggtg catttttatt
    27481 tgctttgggg gctgttggtt tggttattag ctaaaaaagg ctacagtcag aagaaattta
    27541 gaggcattct gtttttaatt tcttccgcag tgttcacgct tagctacttc agcatgttta
    27601 tcagagcctt ctttgtatca gatttttctt ctgtttactt ttcaacgctt tcacacagct
    27661 ttcctttctt tttaggagcg atgtttgcaa ccatgacggg aattaaggac acgactgttc
    27721 gctttcaaaa gaatgttaag ctgtggccaa ggctacatgt tattggagtg atggctggcg
    27781 cttttgctct gttgttgttt ctaacgcttg tgttagattt taaccatatc tttacctatc
    27841 ttttcggttt tgtcttagcc agtctttttg cttcggtaat gatttatgct gcgcgtgttt
    27901 tgagcgatca aacaccaacc tggcaggaac cactgcttgt gacctatctt gcggatatta
    27961 gctatgggat ttatttattc cattggccat tttacattat ttttacacag ctgatgtcta
    28021 actggctggc agtgatctta acggttttct tttcagtagt gttttcaacg ctttcttatt
    28081 acattattga gcctttgatt caaggcaaga caccacagct ttttggttta gcaattgatt
    28141 gtaatcccta taagaaatgg ttatcagggc ttgctttagg actctttttg ttgatggttg
    28201 gtacctgttt gacagcacca agggtcggta attttgagac ccagctttta gtagattcct
    28261 tgcagcaatc tcaaagtaat ctcaataaga cacatacttt ggcagcagga gatgcgcatg
    28321 ctcttagtga tgttagcatt attggtgact cagttgcctt gaggtctagt gacgcttttt
    28381 caaaattaat gccgactgct caactagacg ctgctgtcag ccgcaatttc agtgaagcct
    28441 ttgagctttt tgaaaatcat atccaatcca agagcttatc aaaaacaacg gttttagctg
    28501 ttggtgttaa ttctctttat aattatgcgc aggatattca aggctttatt tatgcactac
    28561 caaaggggca tcgcttggtg attgtgtcgc cctatgatgc taagaatgca gcacaggtag
    28621 cagaggctag agagcatttg ttgcagctag ctaaaaaata tagctatgta acagttgctg
    28681 actggtacaa ggcggcagtc gaaaatccca atatctggta tggtagtgat ggggtccact
    28741 acaataacga cgccaaatta aaaggtgctg acttatatgt ctcaacgatt caggcggctg
    28801 ttgagcgagc agcaaaaaaa gatgctaaat agtggtgcta acaacaattt gttaagaatt
    28861 aataacgaag gcttggtctt acaaacagat caagcctttt catgatgtga tttttagatc
    28921 gtcttgcgcc ctttagcgcg agataaagct ccacctgtta gacagtgtca ttattggctg
    28981 ttattgctga cggtgacgtg cttttaaaaa cggatcatta aataatttag cctgatctaa
    29041 aaaagaaagc gctttcggaa caaagtgaat gcgtcagcca ttatttcaga aaaaatccac
    29101 caagccaaac cccttgttat caaagagttt cggaaattga ttgaaaaaac atcacaattt
    29161 tattgtgaaa tgatttacaa aatgccaaaa aatgatataa tatttttgta aacaaaattg
    29221 tgaaactttt aacaaggtaa aggagtctca aatgactgaa aaaaatagta ctgttgaaac
    29281 aacatctgtt gccgcaacaa ttgacgctct tgttcaaaaa ggtttagtag cgcttgataa
    29341 aatgcgtcag ttaactcaag aacaggttga ctacattgta gcgaaggcct ctgttgctgc
    29401 tttggacgca catggtgagt tagctaagca tgcctatgaa gaaactggtc gcggagtttt
    29461 tgaagataag gctaccaaaa accttttcgc atgtgagcac gttgttaata acatgcgtca
    29521 ccaaaaaaca gtaggtatca ttgaagaaga cgatgtaaca ggtttgacct taattgctga
    29581 gccagtaggt gttatttgtg ggattacccc aacaactaac ccaacgtcaa cagctatttt
    29641 taaatcttta atctccttaa aaacacgtaa ccctattatt tttgccttcc acccatcagc
    29701 tcaagaatca tcagctcatg cagcacgcat tgttcgtgat gcagccattg cagcaggagc
    29761 tcctgaggac tgtgttcaat ggattgaaac cccatcacta gaagcaacta acgctctgat
    29821 gaatcatgat ggtattgcaa caatccttgc aactggtggt aatgctatgg ttaaggcagc
    29881 ctactcatgt ggtaagccag ctcttggggt tggtgctggt aacgtgcctg cctatgttga
    29941 aaaatccgct aacattcgtc aggcagcaca cgatattgtc atgtctaaat catttgacaa
    30001 tggtatggtt tgtgcttctg agcaggctgt tattatcgac aaggagattt atgacgagtt
    30061 tgttagtgaa tttaagtctt accacactta ctttgtcaac aaaaaggaaa aggctctgtt
    30121 agaggaattc tgctttggtg ctaaggctaa cagtaaaaac tgtgcaggtg ctaagctgaa
    30181 ccctaatatt gttggtaagc cagcagcttg gattgctgag caggcaggct ttacagtacc
    30241 agaaggaacg aatatccttg cagcagaatg taaggaagtt tctgaaaatg agccattaac
    30301 acgtgaaaaa ttgtcaccag ttatcgctgt tttgaaggct gaatctcgca cagatggtgt
    30361 tgaaaaggct cgtcaaatgg ttgaatttaa cggacttggt cactcagccg ctattcatac
    30421 tgctgatgca gacttagcta aggaatttgg aacaaaaatt cgtgctattc gtgtgatttg
    30481 gaattcacct tctacatttg gtggtatcgg tgatgtttat aatgccttcc taccgtcatt
    30541 aacattgggc tgtggttctt atggacgtaa ctcagttggt gataatgtta gtgctgtaaa
    30601 tctcttgaac atcaaaaaag taggaagacg tagaaataat atgcaatggt ttaaagttcc
    30661 ttcaaaaaca tacttcgagc gtgattcaat tcaatacctt caaaaatgtc gtgacgttga
    30721 gcgtgtgatg attgttaccg accacgctat ggttgagctt ggcttcttag atcgtatcat
    30781 cgagcagctt gaccttcgtc gtaataaggt tgtttatcaa atttttgcag atgttgagcc
    30841 agatcctgat atcacaacgg ttatgaaagg tactgagctg atgcgtacct ttaagccaga
    30901 tacgattatc gctcttggcg gtggttctcc aatggacgct gcaaaggtaa tgtggttatt
    30961 ctatgagcaa ccagaggttg acttccatga tcttgttcaa aaattcatgg atattcgtaa
    31021 acgtgccttc aagttccctg agcttggtaa gaaaacaaaa tttgtggcta ttccaacaac
    31081 ctcaggtaca ggatcagagg ttacaccgtt tgctgttatc tcagataagg ccaacaaccg
    31141 caagtaccca attgctgact attcattgac accaacggta gccattgttg acccggcgtt
    31201 ggtgcttaca gtaccaggct tcattgcagc tgatacaggt atggacgtgt tgacccacgc
    31261 aaccgaggct tacgtatcac aaatggctaa tgactttaca gatggtttgg cccttcaagc
    31321 cattaagatt gtctttgaaa accttgaaaa atctgttaag gaagctgact ttgagtcacg
    31381 tgaaaaaatg cataatgcct caacaatggc aggtatggcc tttgctaatg ccttcctggg
    31441 tatttctcac tcaatggctc ataagattgg tgcacaattc catactgttc atggacgtac
    31501 caatgctatc ttgcttccat acgttattcg ttacaatggt acccgtcctg ctaaaacagc
    31561 aacatggcct aagtacaatt actatcgcgc cgatgaaaaa tatcaagaca ttgctaagtt
    31621 gctaggactt ccggcatcta ctccagaaga aggtgttgaa tcttatgcta aagctgttta
    31681 tgatcttggc tgtcgcttag gcattaagat gaatttcaga gatcaaggaa ttgatgagga
    31741 agaatggaag gcacacactc gtgagcttgc ttatcttgcc tacgaggatc aatgctcacc
    31801 tgctaaccca cgcttgccaa tggttgagca catggaagaa atcatgaatg atgcttatta
    31861 tggttacgca gagcgtccag gacgtcggaa ataatatcaa tcattaatag taaaaatagg
    31921 agctgcttgg cttctatttt tttatctagc tatgaaaagg gctgtgttag atgaaaaagt
    31981 cggcagtgcc ttgtgttgag atagcttaac tcaggggtag tttctcagat atcatataaa
    32041 gcttttaaga caatggtttt acagagcatt ccatcagagg gggaagcttc atttgccata
    32101 ttcataaagt ggctgatagt tacgacttag ctgcacttag caattagctg aagaaaataa
    32161 catgttgcgt ctatctgatg agctttattt tctaataaaa caaggagtga ttgctttttt
    32221 aatgatgtta atagcgttaa aaacctttat atatcaaaca aaaaccaaaa taatggtatt
    32281 gtcagacttt ttctaaaatt accctttatt aattgacaaa gagggtgtaa aaaattatac
    32341 taaaaatgta atcgattaca ttttctagac taaatttgga gacgttttat gaaagcagct
    32401 acatatgttg ctccaggtca gctggagctt attgatcaac caaaaccaga gattcttgct
    32461 ccgacagatg ctgtggttcg tttattgaaa acaacaatct gtggaacaga cttacatatt
    32521 ttaggtggag atgtcccaga gactactcat ggtaccattt taggtcatga aggtattggt
    32581 attgtcgagt cagtcggctc tgcagtgaac aactttaagg taggtgataa ggttattatt
    32641 tcctgtatca cagcctgtaa tacctgctat tattgtaaaa aaggaattcc tgctcattgt
    32701 gaaagcggtg gctggattct agggcatttg attaatggga cacaagcaga gtatgttcat
    32761 attcctcaag cagatggcag tctttatcat gctcctaaaa ccgttgagga tgatgccttg
    32821 gttatgctgt cagacatttt cccaacttcc tatgaaatag gcgttcagtc tgcaaaggta
    32881 aagccgggtg atacagtgtg tatcgttgga gcaggtccta tcggactagc agctctttta
    32941 acagcacaat tttattcacc agctaagctg atcatggttg acttgtcaga atcacgttta
    33001 gaagcagcta agcgctttgg agcaacagat acgatttgct ctggtgacct tgatgatatt
    33061 gtcaaaaaag tccatgaatt aactgatggt cgaggtgttg atgttgccat tgagtgtgta
    33121 ggctatcctg ctacctttga tatttgccaa aagattattg ctattggcgg gcatgtttct
    33181 aacgttggtg tccatggaaa accagttagt ttggacctac aggacctatg gatcaaaaac
    33241 attacaatgt caactggcct agtaaacgct aatacaacag aaatgctatt gaatgtgttg
    33301 aaatctggta agattgatgc aactaagatg gtaacacatc actttaagct gtcagaggtt
    33361 gaaaaagcct atgaggtctt taaaaatgcc ggcagtaata acgcccttaa agtgattatt
    33421 gaaaatgaca ttacagccta aaggaataag gtataaatag ataaaagtga caacagcatt
    33481 tggaatggtc tagatgctgt tttttagcca acttaactgg ttaagtttat tttcagaaaa
    33541 ctttcaagaa attggttgac aaaccttgtg aaaaagtata caatacaaat tgtaaacggt
    33601 tgcaaaaata gataaaccga gacttagaaa ttggaggcat cctatgaagg ctgtagttgt
    33661 taaccaaacc agcagtggtg tagaggttgt agagcatgat gtaccatcaa tcggtcatgg
    33721 agaagctctt gttaaagtag aatattgtgg cgtatgtcat actgacttgc atgttgcgca
    33781 tggtgatttt ggtcaggttc cagggcgtat cctcggtcat gaaggtatcg gtattgtcga
    33841 aaagctaggt gaaggcgtta cctccttaaa ggttggtgat cgtgtatcaa ttgcttggtt
    33901 ctttgaaggc tgcggtcatt gtgaatattg tacaacaggt cgcgagactc tatgccgttc
    33961 agtcaaaaat gctggctatt cagttgatgg tgggatgagt gagtatgcag ttgttacagc
    34021 tgactatgct gtgaaagtgc cagatggtct tgacccagct caagcatcat caattacctg
    34081 tgcaggcgtt acaacctata aggctatcaa agaagcaggt gccgctccag gacaatggat
    34141 tgttatcttt ggtgccggtg gacttggtaa cctagctgtt cagtatgcta aaaaggtttt
    34201 caatgctcat gtcgtagcag tggacattaa caatgataag ctagagctgg ccaaggaggt
    34261 tggagcagat atcgttgtca atggtaaaga aatcgaagat gttgccggct atatccaaga
    34321 aaaaacaggt ggtgctcatg gcgttgtggt aaccgctgtt tctaaagtag cctttaacca
    34381 agctattgat agtgtgcgtg caggaggaac tgttgttgct gtaggacttc catcagaata
    34441 catggaatta tctatcgtaa agactgtcct agacggaatc aaggtagtcg gatcacttgt
    34501 gggaactcgt aaagacttgg aagaagcctt tgcctttggt gcagaaggtc tggttgtgcc
    34561 agttgtagaa aaggttccag ttgagactgc tccagaagtc tttgacgaaa tggaacgtgg
    34621 tctcattcaa ggaagaaagg tattggattt cacgctttaa ggctgatttc agaaaaagtc
    34681 agcagccaga caagctgatt gtcccaaatg atgaataaag tccttagaat taattttcta
    34741 agggcttttt tggtgaaact aactggtaaa aaaagcttgg tatctaaaga tgtaaaagag
    34801 ccagctagtt attaatacca tgattgcccc ttgaaagaca gtaccagaga aagttggaca
    34861 tattgtaacc tctgatagag atactgggtt tgaacaatat tagagattaa cacaggaact
    34921 caatctagaa gtttatttct ctgctcctca caccccttga taacgtagga caaatgaaaa
    34981 taccaatggg ttaatcaaag agtagtttcc taaaggaact gacttgactg atattgagag
    35041 ctctatcata taagagtggg aagataaatg aaatgatcgt tctagaagat gtcctaactg
    35101 gaaactacct tataaactct tttatggaaa agcgttgcac ttaatttgac aattcgtctt
    35161 cacaaatttt aggaagcact gtaggaaaaa agaataatga cataacatat tgctaaaaac
    35221 atgggttata agctaaatta ttatctacgt ttttagtaac aaggtagtat gatttaaaat
    35281 atagatgaaa aatgttgtgt cccgaataag ggaagttttt taggatacga tacttgtaca
    35341 ttataattta tttataaaat cttttaggtg gatttatgaa agaaattgta agaagtcata
    35401 gattgttata tgtaatagta gcttttttta gtgtaatcag tgcattttta atgaccttat
    35461 tttctattca actgggaaaa atactagata gtatatctaa ttcaagtagt gaattattgt
    35521 ttcagatagt agtgtgtgta tgtaccataa tggcatggtt tataatgata tggtcctatt
    35581 cttattttaa gagttattat gtaaaaaagg tcattttaga tttaaaggag aggcttttta
    35641 taggttattt attacgggaa tttaatgaaa ttgatacttg tgatcgatat aattcggatt
    35701 ttctaaacaa tgtaacaaaa aatattgata taattcagga gaatttattg gttcctagag
    35761 tggctgtgat tgttgatctg gcttcaatgg ttacgagtgt agtagctatt gtacttatag
    35821 aatggcgatt ggccctagta tttttattgc tttctattgt aactgttttt ctatctcaaa
    35881 ttcctggaaa gttaatgagt aaagcaactc gatattattc tgaaaaaagt aatcactatt
    35941 tagcagaaat gactagtttt attgagggat ttgaacagat taaattattg aatattcaaa
    36001 aatggataca aaaaatcgaa caaaatacta ctttagaatt tgaagattct agacagaaat
    36061 atcaatacag aaaagattta gcttcaaata caggaatgtt tttgagcttc ttttctcaag
    36121 tagcctgtat ggttgctggt atattttttg taaggaataa tctactaaca gttggactat
    36181 tagtggccag tattcagtta ttaaatggag tgtttggccc tctacagtct ttcctttaca
    36241 ataaaaattt gatcaaaagc acaggtacta ttttaacaag tattcaagaa gttctagata
    36301 aaacaaattt tgttaatggt tatatagaaa ataagacttt ttatgaagga gacatctcca
    36361 gcatttcgat aaataattta acttatcaag ttgaaaatag aaaaatattt actaattttt
    36421 catttgaat
//
LOCUS       DARYLJ010000021        33282 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYLJ010000021 DARYLJ010000000
VERSION     DARYLJ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33282
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            85..366
                     /locus_tag="TU746_000909"
     CDS             85..366
                     /locus_tag="TU746_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL0891266.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            complement(492..917)
                     /locus_tag="TU746_000910"
     CDS             complement(492..917)
                     /locus_tag="TU746_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL0891267.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(914..1318)
                     /locus_tag="TU746_000911"
     CDS             complement(914..1318)
                     /locus_tag="TU746_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL0891268.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            complement(1340..2119)
                     /locus_tag="TU746_000912"
     CDS             complement(1340..2119)
                     /locus_tag="TU746_000912"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL0891269.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            complement(2116..3048)
                     /locus_tag="TU746_000913"
     CDS             complement(2116..3048)
                     /locus_tag="TU746_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL0891270.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            complement(3326..3598)
                     /locus_tag="TU746_000914"
     CDS             complement(3326..3598)
                     /locus_tag="TU746_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL0891271.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            complement(3662..4099)
                     /locus_tag="TU746_000915"
     CDS             complement(3662..4099)
                     /locus_tag="TU746_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL0891272.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            complement(4086..6218)
                     /locus_tag="TU746_000916"
     CDS             complement(4086..6218)
                     /locus_tag="TU746_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL0891273.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            complement(6386..6712)
                     /locus_tag="TU746_000917"
     CDS             complement(6386..6712)
                     /locus_tag="TU746_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891274.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
     gene            complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TU746_000918"
     CDS             complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TU746_000918"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0891275.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TU746_000919"
     CDS             complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TU746_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL0891276.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TU746_000920"
     CDS             complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TU746_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL0891277.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            complement(9483..10355)
                     /locus_tag="TU746_000921"
     CDS             complement(9483..10355)
                     /locus_tag="TU746_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL0891278.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            complement(10514..11839)
                     /locus_tag="TU746_000922"
     CDS             complement(10514..11839)
                     /locus_tag="TU746_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL0891279.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            complement(11823..12545)
                     /locus_tag="TU746_000923"
     CDS             complement(11823..12545)
                     /locus_tag="TU746_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0891280.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            12717..12872
                     /locus_tag="TU746_000924"
     CDS             12717..12872
                     /locus_tag="TU746_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891281.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            12913..13815
                     /locus_tag="TU746_000925"
     CDS             12913..13815
                     /locus_tag="TU746_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL0891282.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            13815..14630
                     /locus_tag="TU746_000926"
     CDS             13815..14630
                     /locus_tag="TU746_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL0891283.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(14815..16236)
                     /locus_tag="TU746_000927"
     CDS             complement(14815..16236)
                     /locus_tag="TU746_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0891284.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(16263..18125)
                     /locus_tag="TU746_000928"
     CDS             complement(16263..18125)
                     /locus_tag="TU746_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL0891285.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            complement(18130..18969)
                     /locus_tag="TU746_000929"
     CDS             complement(18130..18969)
                     /locus_tag="TU746_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL0891286.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TU746_000930"
     CDS             complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TU746_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL0891287.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            complement(20715..21542)
                     /locus_tag="TU746_000931"
     CDS             complement(20715..21542)
                     /locus_tag="TU746_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0891288.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            complement(21543..22340)
                     /locus_tag="TU746_000932"
     CDS             complement(21543..22340)
                     /locus_tag="TU746_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0891289.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            complement(22858..23367)
                     /locus_tag="TU746_000933"
     CDS             complement(22858..23367)
                     /locus_tag="TU746_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891290.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            complement(23364..23987)
                     /locus_tag="TU746_000934"
     CDS             complement(23364..23987)
                     /locus_tag="TU746_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0891291.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGKVLVDEQDIWKTKERTFFKTIIGYVFQNYSLIENKTVYDNLRLIN
                     KDKKIIADVLEKVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRKIILADEPTGALD
                     SEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDVIIDLKDIGSEI"
     gene            complement(23987..25969)
                     /locus_tag="TU746_000935"
     CDS             complement(23987..25969)
                     /locus_tag="TU746_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891292.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENNDFILASNII
                     YNSLFSSEAIKKINDLSASLNFSINPVEVYQTVKLNIQSLEHQIFLSKILQIIICGIV
                     FLLIYQYAQMFVALKQNDYVKKIILGLSKTRIAISSLNYFIVTITMVILLTFMLTGQV
                     ELLYIGIASLMVLIFSTIMSFRKLSEKYTQILKGDD"
     gene            complement(26036..26341)
                     /locus_tag="TU746_000936"
     CDS             complement(26036..26341)
                     /locus_tag="TU746_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891293.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            complement(26508..26825)
                     /locus_tag="TU746_000937"
     CDS             complement(26508..26825)
                     /locus_tag="TU746_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891294.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(26807..28096)
                     /locus_tag="TU746_000938"
     CDS             complement(26807..28096)
                     /locus_tag="TU746_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891295.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            complement(28098..28541)
                     /locus_tag="TU746_000939"
     CDS             complement(28098..28541)
                     /locus_tag="TU746_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891296.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            complement(28906..32457)
                     /gene="smc"
                     /locus_tag="TU746_000940"
     CDS             complement(28906..32457)
                     /gene="smc"
                     /locus_tag="TU746_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL0891297.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGISKVVSVKLKDTQDLTYLS"
     gene            complement(32458..33150)
                     /locus_tag="TU746_000941"
     CDS             complement(32458..33150)
                     /locus_tag="TU746_000941"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL0891298.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
BASE COUNT         9547 a         7787 c         6090 g         9858 t
ORIGIN      
        1 aacgagaagc cttcaaaaaa aaagatgaca accatcagct tttatggtaa aatggttggg
       61 tatcttacgg gaaaggagag gactatgcct acaccattgg agcagcggca gctcaagcag
      121 cagaagcaag agcaggtctc gcagcaaaaa tttcaagagt ttcaagacct caatggacac
      181 agtagcaagc tcaaggaact tatttttttt gcccgtattg ctgtttttag tttaatcact
      241 gtcttgtttg catttgtcct tcttgtcatg aatttggcac cggtttgggc ctttctaatt
      301 gctagtgcta tcagcctagc catcacttcc tttctttcaa aggccatcac gttattaatg
      361 tcataaacag ttagagcttg gcttcgctaa gctctttttt cattactctt attgcctatt
      421 ttcttgaata aacgagtagc ccacatcaca aaaggccctc catagctgag agagccctta
      481 tttttgcctt attattcttc agacttattg ctagctgctt ctttttctga atcatcttca
      541 ggatagttga taataatatc ctcttcatcc agatcaataa tcacatcatc agccttgtca
      601 tgctctgaag cagcttcctt tgcctgatga acaaattggc tggtcttttc cttgataaaa
      661 tcaaacacct gatcagtggt catatcccct gattcaaacc tggtttttaa atcattaaag
      721 gtatggcgag ccagctgact gtactcactt cctttttctt tagccatttg atgatattcc
      781 tcaggatttt gacgataggc ttcataggcc ctttgtgcgc gagccttcaa gacctttcct
      841 ttttcagttg acaagaaata agcggtagct gctcctgaag ctacaccaat caccaacgtt
      901 ttaaaaaaat tactcatgac cttttctcct ttttaccaaa taatttagaa gcgaccttgc
      961 cgacaagagc tactttaccc acctttgcag cattgcttgt ggcatttgtc gcccgacgtc
     1021 caaggtgtct ggcctgcaca ttcaaatcag aaacactttc tgacaaatct gcaatagcaa
     1081 caaagagagg atctattgtt gtcatcttac cattcacatc atctaccagc acattagcct
     1141 tagctaatat ttcattggtt tgataaaggg taacattgac atcactcgtt aaaacggtaa
     1201 tggttttttt agcctcatca actgcctctg acaccttttt taacaccaca atcaaaaaaa
     1261 taaccagagc aacaaaggct aatgcgatta tcagcaatga aatgcccact aaattcataa
     1321 acgtctcctc tttctatccc tattcttgat aataagaaat tcccttttgt cgatgccttt
     1381 taaagataaa aacaatcgca atgataatga gcagcaccga catgtattga gaaacacgaa
     1441 ttcctaaaag catcaggctg tccgttcgca tgccctcaat caccaatcga ccacagccat
     1501 accaaatcag gtaaaatgag ataatatccc catctactaa tgacctgggc ttacgccgcc
     1561 acaccatgat aatgacaaag ccaatcaggt tccacatgga ctcatataaa aaggtgggaa
     1621 cacgatagct gccatctata aacatctgct ggcgaataaa actaggcagg taattgagct
     1681 ggctgacagc cctgccatag gcctcttggt taaagaaatt tccccatctg ccgatggcct
     1741 gagcaagcat gacactaggc gctgcaatat ctaagaaatg gataggattc agcaccttat
     1801 agtagcaata aacaaagaga acaatggtac ctgttatcaa gccgccatag atggcaatcc
     1861 caccattcca aatagcaaag atatcactca aatgctgaga ataataggac cattcaaagg
     1921 ctacataata gattcttgct ccaataattg ccaaaggaaa ggcaatcaga ataaaatcaa
     1981 taatatcatc actggtcatt ttttttcgcg gggcttcttt ggctgccaaa taaaccgcta
     2041 aaagtaatcc caccaagata caaaccgcat accagtgaag actaagagga ccaagcttaa
     2101 aggctattgg attgatcatt tgccctcctc atttttgctg attaaacgtg taaggcgctc
     2161 ctcaaaggtt ttggtagcat caaagcccat ctctttcgca cgatggttca tggcagcagc
     2221 ctcaataacc actgacacat ttcgacctgt tttgacagga atgcgaatcc ttggaatact
     2281 gacaccagaa aaggtaatct cttcattgcc attgcccaag cggtcaaaga ccttgccagc
     2341 ctcaaaattc tccaaataaa tagccaactg cacctgtgag gaatccttga cagcactagc
     2401 accgtacagc gacatgacat caataatgcc aacaccacga atctcaagga gatgacgtaa
     2461 aatctctgct ggctcccccc atagcgtctc ctcatcttta gcaaagacat ctactcggtc
     2521 gtctgccacc aagcgatggc cacgcttgac caactctaag cctgtctcac ttttaccaat
     2581 acctgaatca ccttggatca gcacccccat accgtaaata tccatcagca ccccatgcac
     2641 acttgttcgc tctgctaagg aagcatcaag aaaataagac atctcaccag ctaagcggct
     2701 ggtagatacg cggctgctaa acagagcaat accttcctcc tgcgctgcct gaaccatctc
     2761 ctctgggata gctaggcccc tagatacaat cacagctggc gtgtcttttt taaacatttc
     2821 ctttaagact gagtagcgat tgtgtgaggt catctgagtg aggtaggacc attctttcat
     2881 gccaaacagc tgaagccgct ctggggcata gtaatcaaaa tagccggtca tctcaagacc
     2941 cggacgcgaa atatctgagg tcgttatctc cttttctagc aagtcatcag ttgcatagac
     3001 aacgtcaagc ttgacctttg tgactaacat cttaacggta actgtcataa tttctccttt
     3061 tttaatatta tatcataaat cactatctaa gcccttacaa atacttattt ttcaaagaag
     3121 ctttcaaagt gcttgatcat actaaaaaag aatcctgcaa cagctgcctc aggctcactt
     3181 aaagcaggca ctagcctaaa gcggacaaac aacaaaaggc cctatctcat cagataaagg
     3241 cctacagcca gctttatttc tgataatcac gctagaggca ctattaaaat tcctgtcaag
     3301 cttttaatag tcgctcgctg tggtcttacc aaaaccagcc ttcatcttca tcatttagga
     3361 catcagcatc cttgcgacgt cttggtcctc tcccgtaacg ttcttcaagt aggtcctctt
     3421 tatatggtag gaagatggct aaaagaatat aaataacaac cccaaagcga gtaaaataga
     3481 tcaataaggc ggcaagcaca cgagctaggg gcaaatccca gccgtattta tcagctaaac
     3541 cagagataac tccagccact agcttatgct ttcgttgctt ataaaattta gattccatgt
     3601 ctcctcgcct ccttattcta tgatactagt ttattccttt tttagcaaaa taaaatcagc
     3661 cttacgactg atttttttca atgagcctgc catgacacct gccgcaggca aataccgcca
     3721 gattgatagg acgttttcgg tcataagctt ggccgcaatc ttgacagatg tagaggtaat
     3781 tagcttgatg tgactgtaat tttggagcgt atctcagacc gtctacttgg tctagaagct
     3841 ccttaaaggc ttgatcctta tgccgaaagc ccagcccctc aaaatagagg tgataatgac
     3901 aaagctcatg cctaacgatc tgtctaaaga cagtctcccc atgctcctct aagattttgg
     3961 gattgaaatc cagatgacca tcctttggaa aaaaacgtcc gcctgttgtt cttagtcgtc
     4021 tgttccaaga agcctgatgc ttaaagggct ttccaaaatc agctagcgag acctctctaa
     4081 cataatcagt cagactcacg aggcggcact aagcttaggt tgaccttgtg gcggtctaag
     4141 tcaaccttag aaacccaaac agtgactaaa tctccgacag aaacgacctg acttgggtga
     4201 ttgacaaagg cctcactcat ctctgaaatg tgaatcaaac cgtcctcatg tacaccaata
     4261 tcaacaaaag caccgaagtc aaccacattt ctaacagttc cctctagcct ttgaccaaca
     4321 gccagatcct ttacactcaa aatgtccttt cgaagaacag gagcttcaaa gtcatcacgc
     4381 aagtctcttc ctggcttcag caaatcagca atgatatcct tgagcgtttc ttgaccaagc
     4441 gtcaattgct ctgccatttc ctcaagatta accgcctgta atttggccct tgcaggctca
     4501 tctaagtctt taatcgcaag taattgaaag agctttttga cagccggata ggcttctggg
     4561 tgaacgcctg tattgtctaa tatattctta gcattgggaa tacgcaagaa gcctgctgcc
     4621 tgctcaaagg cctttgcgcc tagtctaggg acctttttga tctcagcacg tgaggtgatc
     4681 tctccatttt cttcacgata cctgacgata ttctcagaaa tggttttatt tagccctgaa
     4741 acatgagcca gtagggctgg actagctgta ttgatgttaa ccccaacctg attaacaacg
     4801 gtatcaacga caaaatccag atgctcagat agctttttct gactaacatc atgctggtat
     4861 tgtccgacac cgattgcttt tgggtcaatt ttgaccagct ctgctagcgg gtcttgcaag
     4921 cgacgcgcaa tagagatggc tgagcgcttt tcaaccgtca gctctggaaa ttcatggcgg
     4981 gctagctctg aggccgaata aaccgaagct ccgctttcat taacaatgac ataagaggtt
     5041 tctggaaaat cctttagcac ctctgcaaca aaggcttcac tctcacgact ggctgtgcca
     5101 ttaccaatgg caataatatc aatctgatag tcagtgatga gctgagctag agctactctt
     5161 gctgcttgaa tcttagcttg attagctggt gccaccggat agataacctg agtagttaac
     5221 agctttccag tcggatcaat caccgctaat ttggcccctg tcctaaaggc cgggtcaaag
     5281 cccagcacca tttttccctt tagtggtgaa attagcaaaa gatgacgcaa attttccgaa
     5341 aagagcttga tagcaccgtc ctcagccatt tcagttaatt ctgtgcggat acgtcgttcc
     5401 atagcaggaa caattttttt cttgattgtt tggttaataa catcatcaat ataagcattg
     5461 tgctccttaa agcgaaggct gaaaaagcgc agcattttgt ctatatgatg ctcaaaggat
     5521 acctttaata cgcctagctt ttccccacga ttgagagcta gggtcctgta gccctgcatg
     5581 ttagataccg tctcagaaaa cgcatagtaa atctgaaaga cctgcttgtc atctaagctg
     5641 gcttccttta ggctagaggt tatacggcta tacttccaaa tctcattata ggtccaggac
     5701 cttagcctgc tatcctctga catggcttcg accaaaatat caacagctcc agcaagggct
     5761 gcctgtggat ccgaaaaacc ttctgtgata aaggcctctg ccttagtttc taggtcttgt
     5821 gcattttgaa ggatcagtct agctagtcca gataagccgg cttctcgagc aatggttgcc
     5881 ttggtacgcc gcttttcctt gtaaggcaaa taaagctcct ctaggtcagc caatttatca
     5941 gctgcttcta tagcttcctt aagggcagct gttagtttcc cttgtccttc gattttagca
     6001 agaatggtgt ctttacgctc cctaagctgt gtgagggact tatccatatc aataatggcc
     6061 ttgatcacca cttcatcaag gttacctgta gcttccttac gatagcgcgc aataaaggga
     6121 atggtattac cctcagcggt aagggtaagc acttgactaa tctgttttgg ggtgaccccc
     6181 aacgcttctg aaatgttttg atgattcata ttttccataa cagttcttat tatagcacaa
     6241 agaaagaggg atagaacaag ataaaagctt tatgacaaat aagtgtcaag aaaacaaaac
     6301 ttatcttttc agatacttct aaaggctaag aaaaaacgat ctccaaacgg aaatcgtctt
     6361 ttagctactt agtggttagt caaaattaag tgagatcttc taactcttcc aactcctttt
     6421 caaacttatt ataaagttca tcaatttcac ttactgattt tgctgcacct accctagctc
     6481 tgaattgtct gttataagac ctaaagccat cctctcctag tttatgctta aatcgtgtta
     6541 acagattaag gatttgcagt cttgaccccc agcgcgctgc actaagcgac ttggtgtcgt
     6601 taatcgtatg ctctataaca tgcccacgag aaaacgcctc tacttttgtt gtgctaactg
     6661 ctactgttgc taaggctagc gctgcagcac tagttaatag taattttttc atgatatgac
     6721 tcctatttgt ttttttatgt agttattata taatattaat aagattatag tttactaata
     6781 tatatatata tatatttcta ataccagtaa cctttgtctg aaaatagcta gatcgtgctt
     6841 atcaaagaaa gcaaaaaagc ttcactctac aggaagtaag agagaagctt ccacgctaat
     6901 aggatactga tctgacatca tcaaaacacc aattgaggag agatttagcc ctcattccaa
     6961 ttgctctttc atcgcctagt ccttttctta tccgaagcgt ccggaaatat aatcctctgt
     7021 acgcttgtcc tttggctttg taaatagttc agctgtatcg ccaaattcac aaatatctcc
     7081 tgtgaggaaa aaggctgttt tatctgacat gcgtgaagcc tgctgcatgt tgtgggtaac
     7141 gatgataatc gtgtaatcct gctttaattg ctgaaccaag tcctcaattt ttaaggtaga
     7201 aatgggatca agagcagagg taggctcgtc catgagcaac acatcaggtg ctacagcaag
     7261 cgctcttgca atgcaaagcc gctgctgctg tccacctgat agggacatgg cactcttttt
     7321 taagctgtct ttgacctcgt cccaaatggc tgctcctctc aaggactgct ctaccagctg
     7381 atctagagtt ttcttgtcct taaggccatg tgtcctagga ccataagcca cattatcata
     7441 aatagacatg gcaaatgggt tgggctgctg aaagaccata ccaacacgct tacgcagact
     7501 gttgaggttt attgctttag catagatgtc ttgattgtct aagagaacct ctccttcgat
     7561 acgacaggaa ggaatcaagt cattcatgcg atttagggtt tttaaaaagg ttgatttgcc
     7621 acagccagag ggacctatca gggctgtgat ctgattttct ggtatgtcaa tggagatatc
     7681 ctttaaggcc tgaaatgctc cataaaagac attaagctgc ttggttgaaa aagctcccat
     7741 tttagacgac tcctttcact aatcggcgtg ataataagct tgatagggca ttgatcagca
     7801 agacagttat gagtaagata acacccgttg cataagcttc cttgacatgt agcccttcgc
     7861 tagacagcat gtacatgtga agagctagtg agcgtcctga tgacatgagg ctggttggcg
     7921 tattggtaga ggtgcctagg gtatacatca gggctgctgt ctcacccaca acacgtccaa
     7981 tcgctaggat taccccggct agaataccag gcattgcagc cggcagcact attttaaaaa
     8041 tcgtccttag cttacctgct cctaagccaa ggctagcctg acgcaagtga tcactaacag
     8101 agaggagcgc ttcttctgtt gatcgaatga taactggcaa caccatgatt acagacgtca
     8161 gaatacctga taaaagagaa tattgcaggc cgaaaaaaac cacaaagaac agcatgccaa
     8221 aaagaccaaa aacaatcgaa ggaatccctg atagcgtatc agctgcaaga cgtattgccc
     8281 ttacccatag tgagtcctgc ttagcgtatt ccacaagata gaagccagca aagacaccaa
     8341 tgggcaaggc tagcactaag gtgcctaaaa ctagactaac agttgagata atcgacggca
     8401 ttagagaaac attgtcagag gtataggtcc atgaaaataa ggataacgac agactaggca
     8461 agccttttat cagcataaag gcaataatca aaaataagga gccaaaggtc aatagcgaca
     8521 aaagatagac cagggctttt agtaaatagt tagtcatgag ctgattttcc tttcacataa
     8581 gcaaagcaag cattaatgat gagaataaag ccaaagagga cagccgatgt tgcaatcaag
     8641 gcctctctat gctgaccaga agcatatgcc atctctagga caatatttgt cgtcatggtt
     8701 cttgtgccct caaataatcc tgatggcagc acaggctggt ttcctgctac caaaataact
     8761 gccatcgtct caccaatggc acgaccaaat cctaaaataa gagcggaaaa aaggccggat
     8821 ttggctgctg gcaggatcac tcgaaaaata ctcctttcat gactggctcc cagtgcaaga
     8881 ctagctgaat aataagcctt tggaacagct ctgatagcag actctgaaag actgataagc
     8941 gttggcaaaa tcatgattcc taagagcaag gaggcagtca gcacactcat gccattacca
     9001 gcaaagctcc taatccaagg cactagcact tgaagaccaa aaaagccata aacgatagac
     9061 ggaatggctg ccatcagatt aacagctgac tttaaaaagc catagcatgc tttaggacaa
     9121 tagtaaacca taaaaactga ggtcaatata cctgttggca caccaatcac cattgcacca
     9181 agtgtgatga caaaagaccc tgcaatcatc ggcaaaatac catagcttgc cggctgattt
     9241 gacggtgacc aatcatttcc tagcaaaaag gctctcatac catacttagc aataaaggga
     9301 aggccattac taaaaataaa gatacagatt aaacaaatag caataattgc catcgctgca
     9361 ctgagaaaga agataacttt aaaaaaatcc tctttaaagg cttgtttatt cactgatgat
     9421 cctttctaag aaaggaaagc aagaacaaaa cacctcttct ttgccttcct tctaatcgtt
     9481 ctttatttga ctttgtccca gcttgttagc ttgccgctaa agacatcagc cagcacatct
     9541 atgccaatat tacttacctt attgtccttg tgaacaatca ctacgatacc atcaagggca
     9601 atcgcatcat caattaagcc cttgctctcc tcagttgtta ggtcacgaga aaccataccg
     9661 atgtctgctg ttttttcctt gacggcggtg atacctgctg atgagccatt tgaggtaata
     9721 tcaatgctaa tggctggatt ttctttcttg tatgcttctg ctaatttttc catcaagggt
     9781 gaaactgagg ttgagcctac aattgacagc ttgcctgata agcccttact gctataggct
     9841 ggcgcgtctg tttttgcttc gatcaatcga ttgtctctaa caatctcctg cccctgcttt
     9901 gagtcaataa aggtgataaa atccttacca actcctgata ggtctgagga ccatacaata
     9961 ttaaagggac gctgcagagg gtatttcccc tctaaaatag tctcacgact agcctttacg
    10021 ccatttacct ttagggctgc aacgtcgcta tttaaggacc ctagcgagat gtagccaatg
    10081 gcacgactat ttcccttaac agaggagatg accccttctg tgctattttg gataatagct
    10141 gtttttgctg tttggtcaat ctctttgtca ccgtcctttt ttagaatgcc tgtcatttcg
    10201 gtaaaggctc cacgagtacc tgagccattt tctcgagaaa caaggtcaat cctgtctgct
    10261 gcttttccag catcagcact gttattgcca caggctgcaa gacctaagcc tgataagcca
    10321 atagctgcca tgatcagcat ttttttgatt gtcataagaa tcacccttat cttttatgat
    10381 attgtgttgt aggcttgcta cacctatagc ttatcaggtc tttgtaaagg tttatccctg
    10441 attaatgtaa agattttgta aaacctaaaa cagccactac caaggctggc cttaagtagc
    10501 tggtagtgac tgtttacttg ttgatagctt ctggtaagaa taaggtaaat tggctgccct
    10561 ctcctagctg acttgtgact gttatctgac cgccaagaag ctgactcagc tcctttacaa
    10621 tggctaggcc taggcctgtt ccaccacttt gcctgctacg tcccttgtta acacgataaa
    10681 agcgctcaaa aatacgatct agctcaattt ggctaatgcc aatcccagta tctgcaactg
    10741 taatggcaac accaccagca accctttgac tggatagctg aattctgccc ccattgtctg
    10801 tatactgtat cgcatttgat aagagattta acatgatctg cgataagagg tattgatcag
    10861 atgtcacaac aatcgaatcc tccaatgcat agcttagctc aagctgcttt tgctctagct
    10921 gtggtctcat gctctgacct gtatacagca ggaagttcct gagctgaaac tctgtcaggt
    10981 caagtggtgt cttgttagcc ttggataagg tcagcaggtg ctcaacaata cgttctagac
    11041 gcaagctttc attgtagata atgtctaaaa agtcttcttt taggcttgtt tcatcgtcag
    11101 gcatttcctt aatcgtttca gcaaagccct tgatcgatgt aaccggtgtt cttaattcgt
    11161 gagaagcatt agcaataaac tccaaattta gcctctcata atgacgaatg gccgtcagat
    11221 catataagag cactaaaatc tccttgacaa catgcgactg gttaaagata ggcacaaggg
    11281 taacctccaa gatcaaatca ccatcatgta ggcctgttaa ttccttcttt aatgtctgct
    11341 tttggtcaaa gacttgatta actaaggcta tcagatccat tcgtttaaga tcctccaaga
    11401 ccacaaaagg tggcttagcc tctggaaaat aagccggtaa ggatttgctg gtcagcaaca
    11461 gctccctttg attggagact aaaagcatgc ccatcgtgag atgagaggtt acagcctcca
    11521 cattttttga taaggctttt agccttgctt ccttttgtaa taggtcactt tttagctctg
    11581 tcagctgctt agcataagca cttaaatcag cctgccccac taggagaaaa tggtcactag
    11641 ctgtcaaaag atggtggtgc aaggctctga attcacgctc ccatctaaat agcatgctca
    11701 agacataaaa gctagctacg agaccagtac acagcactac tagagtcagc acctgatgcg
    11761 gcccttgcca aatcagacca agagcagcca gcaagcaaag ccctagcagc atgctcaaac
    11821 gcctaagatg tcctatcatt ctttagctcc ttaaatttgt agccatagcc gcgaatggtt
    11881 tgaatatact gaggcgcctt aggattgtcc tcgatttttt ctctgagctt gccaatatga
    11941 acgtctacca gacgtgtttc ttggccaaag tcataacccc agatacgctc taatagccgc
    12001 tcacgcgtca gggtcatatt agggtgcttc atgagataga gcagtagctc atattccttt
    12061 ggggttaacg gcaatagctc cttgtcctta tagacctcat gtcgctctgg gtacagacgc
    12121 aattgactca tcgtataaaa aggctcacga cgctcttcac catcaccaga aatctctgct
    12181 tcagtacgcc ttaaaatagc cttgacacgc gctaataatt ctctaggact aaagggcttg
    12241 gtcacataat catctgcccc cagctccaaa gccaaaacct tgtcaaattc atcactttta
    12301 gcagaaacca tcataattgg ggttttgctt cccttagcac gaagcctttt gcagacctcg
    12361 ataccgtcta attgcggcag cataatatct aacacaataa aatcataagg ttctctttca
    12421 gctaatgcca aggcagtacg gccatctgtt accatctctg tcacaaagcc ctccttggcc
    12481 aagtgataat ccagtagcct taagataggc tcctcatcat ctactaataa tactcgtttt
    12541 gtcatttcat agctcccatc agccacatta tatcatattt gtcagtcaat ctaatgacac
    12601 actgcttgac ggcctgaagc ctaaaatcaa tcagaagata aaaagatgtt ttagctttgg
    12661 ctttaccgtc aaatgattgt ataatagagc tatattgatt gaaagaaggt atacctatgg
    12721 caattactca taagaaaaat gaccagctcg aaaagatgat ggcaggcttt gcgtctatcc
    12781 cagattttga taagccttta gagcttaacc aagatggaaa gctagtcact gaaaaaccaa
    12841 agccacaagt caagacagct aagcaggact agcccttatt ggcgtcgtta acatatagaa
    12901 aggatacggt gaatgtcgct tttttcaaat ctgccaccca gcgtgcttca atggtttgcg
    12961 atttttctat ccattatcat tgaagccctg ccttttgtat ttttagggac tattttatct
    13021 ggctgtattg aggttttcgt cacgcctgat ttagttcaaa gatacctccc tcaaaataag
    13081 tggctaagaa ttttatttgg tacctttatt ggctttgttt ttccttcctg tgaatgtggt
    13141 atcattccta ttattaatcg ttttttagaa aagaaggtgc ctagctacac tgctgttccc
    13201 tttttagcaa ccgctccaat tattaatccg attgttttat ttgctaccta ctctgccttt
    13261 gggaattcgc tgcgctttct catgctaagg cttttaggcg ccattttagt ggctgtcagc
    13321 cttggcatca tgctagcctt cattgttgat gagaacattc tcaaggaatc aacccagccg
    13381 gtgcattgtc atacttacag tcacgaaagc ctgccaaaac ggctttactt ggcactggct
    13441 cacgctattg acgaattttt tgatacagga aggtatctag tctttgggac cctgattgct
    13501 tcagccatgc agatttatct gccaacaaag gtgctgacag cgatcggaca tagccctttg
    13561 acagccatct tagtcatgat gctcttagcc tttatcttat ctctttgcag tgaggctgac
    13621 gcctttattg gagcttcgtt attgtcaacc tttggagttg ctcctgtttt agcctttctc
    13681 ttaatcggcc ctatggttga catcaaaaac ctcatgatga tgctcaattc ctttaaggga
    13741 gcctttattg ttcaatttat cagtgtatca gctgtgatga ttaccatata ttgcttactt
    13801 gtgggggtgc tgtgatgatt cgctttttaa ttttagcagg ctattttgag ttgaccatgt
    13861 atctagagct atctggcaag ctaaatcaat atatcaatat tcgttacgct tacttagcct
    13921 atatttctat ggttctatcc tttatccttg cattggtgca gctatacact tggactaaaa
    13981 acatcaagct acacagtcat ttaaaaggta aggtcgctca gctgaccagt ccccttatcc
    14041 tggtctttcc tgttttggtt ggcttgttag tacctacagt cagcttggat tcgacgaccg
    14101 ttgccgccaa gggctatacc tttccattag ccgcaggcgc ttcaaaaaca ggggtcagtg
    14161 atgatggtac tactattcaa tacctaaagc cagacaccag cctgtacttt accaaatccg
    14221 cctatcaaaa ggaaatgctc aatgaactga aaaaatacca aggcaaatca gccatcacca
    14281 ttaccactga caattatatg gaggtaatgg aattaatcta cctttaccca gacgaattcg
    14341 ttgatcgtac gattcagtac actggctttg tctataatga gccaggacat gacagctatc
    14401 aattcctctt tagatttggg attatccatt gtatcgctga ttccggtgtg tatgggcttc
    14461 tgaccactgg taatcaagaa agctatgcca ataacacttg gctgaccgtc aagggccagc
    14521 tgcacatgga atatgacaag accctagagc agcagcttcc tgtccttcaa atcgaggaag
    14581 cacaccaagc cccagagcct gataaccctt atgtctatag ggtattttaa caagcattaa
    14641 gcctccacac ctatgacaca ggtctatgga ggctttttgt taggggacag tacaaagacg
    14701 taattgagtt cgttccattt aaatgaaatg gctaaaagcc gtatagcatc agccttttaa
    14761 aagacgtgtg ctatacggct ttgctattgt tggtaaagcc tttgaggcta ctttctagct
    14821 ctcctcagac aggctacgcc cattggtctc aatgaccctt tgataccaag caaaggattt
    14881 tttcttgtag cgtgtcaaat gaccactgcc atcatcatgt cggtcgacat aaataaagcc
    14941 ataacgctta cttagctgag cagtcgacat agaaacacaa tcaatacagc cccaggaggt
    15001 atagcccata atgtcaacac cgtcctcaat agccttagca acctgcaata aatgctgcct
    15061 catgtaatca atccgataat cgtcctgaac tgtccagtga ccatcctttg tctgtactag
    15121 cttatctttg gcgccaagcc cattttctac aataaagaga ggaatttggt acctatcata
    15181 gtaatcattc aaggttatgc gaaggccaat tggatcaatt tgccagcccc attccgaaga
    15241 gggcagatga ggattaacca agccacctaa aatattgccc tcccctcgtt gataatgatc
    15301 cgggtgatga gactgagtca cactcatgta atagctaaag gataaaaagt caaccgtatg
    15361 ctgcgccaaa agctcactgt cgcccggttc aaattgaatg tcaatgtgct gctccttaaa
    15421 aaaggatttg gcataggaag ggtattttcc tctgacctga atatctgaga acaggagatt
    15481 acgttgctca aactgcttcg cagctaaaat atccctcgga tcagaggtca ttggataggc
    15541 tggcatagcc aaaatcatac agcctatttt aaaagcaggg ttaatcaatc tagcaagcct
    15601 tgtcacacta gcagacgcta ctaattcatg gtgaatcgct tgataaagct cctgcggagt
    15661 cagcttttcc tttggtgtca tgatagcacc actggtaaaa ggcatatgca ggattgaatt
    15721 aacctcattg aaggttaacc aatacttaac cttgttcttg tagcgctgca tgacagttgt
    15781 cgcaaaacgt tcaaagaagc caaccatacg acggtcagtc cagccattat agaccttagc
    15841 tagatgcagt ggggtttcgt agtgagatag ggtcactaaa ggctctatgc catgtgctat
    15901 cagctcatca aacaaatcgt cataaaattg tagccctgct tcgttaggct ctgtctcatc
    15961 gccctgagga aaaatacgag accaagcaat tgatgtccgg aaaaccttaa agcccatttc
    16021 tgcaaagagc gccacgtcct ccttgtagcg gtgataaaaa tcgatggcct ctagcttcaa
    16081 attagctgct gttggctcag ctgtatagtc tcctaagccc ccttctggta aaacatcctg
    16141 aaccgacaag cctttgccat ctgttaaata agctccctca acctgattgg cagcaactgc
    16201 ccctccccac aagaaatcct ttggaaaaca aaccatatta tctcctcctt caattcatct
    16261 ctttagagaa taacgagagc aacatcatgc tgagtgatat gctccttgtt gtcattaaca
    16321 atgatttcga gctgctcaga gctattggtc accacaaatg gagtcactaa agaatagccc
    16381 ttagagccaa tcaattcaag atctatacgt agcagcggct gcccctgctt aacagtatca
    16441 ccagccttaa ccagctgctc aaagccctgt ccttttagct caaccgtatc aataccaaca
    16501 tgaattaaga cgtcaactcc cttggcgttc tttaaagcaa tagcatgctt tgttggaaaa
    16561 agggtgataa cctcgccatc aaatggggca tagacatatt cctcattagg taaaatagcc
    16621 agcccctctc ctaaaagctt agacgaaaag gtttcatctg gcacctctga taatggaagc
    16681 actgtgccaa ccatcggagc ataaatagat tgctttgctg ataagccact ttttactggc
    16741 gtgctatccg agtcagctga cccctcctgg tcaacctcct catcaatgcc aaaaaaccag
    16801 gttaatgtaa aggttagagc aattgttaag cccgctgcaa ttaaggcatt ggtaaaatta
    16861 gcagagctag tcgggctaat gtattgtggc aatccaatta gtgatggcac cacaaaagta
    16921 taagaggcta tattaacaaa gccaatatag gcgcccacaa ggccaccaga aatcattgca
    16981 gcatagagcg gctttttaaa ctttagagta atgccataaa gagcaggctc tgtaattcct
    17041 gccaataaag ctgataagcc tgctgctaag gcaacctgac gggtttgctt ttgctttgat
    17101 tgacatgcta cagccaccgc tgctgatccc tgagctaggt tagaggctag cattgctggg
    17161 aggattaaaa catctggagt tgctacagag gccgccagaa aaataggagc aaaggcccaa
    17221 tgcatacccg tcataacaac aagcggcata attgcaccta aaatagcaag agccagccaa
    17281 ggagcaatat ggtaaatcgc tagcaggcta ttagacaagc cctgtcctat aataacaccc
    17341 agaggtccaa taacaactaa ggctagaaag cctgaaataa aaataatcaa ggtcggctgc
    17401 aggaagctct tcatcacact cggtacaaaa cggttaacct ctcgctcaat gtattgcatc
    17461 aggtaaacca taattaaaat cggaataact gacgcaccat agctagcagg tgtcaccggc
    17521 gctccaaaca aagccatagg tttacctgta gctaccatcg taacaaaagc tgggtgtagt
    17581 aaaatccctg caacagttgc tgctaataca ggtgtgacct taaagcgtgc cgcagctgaa
    17641 tatgcaatca tgattggcat aaaataataa gcagcatctc caaaaaaatt aataaaagca
    17701 actgtttgag agtccgtacc tgctagacca agcataggca ccaagatccc aaccaccttt
    17761 aacataccgc ctcccagtaa ggcaggtatc agtggagtaa tcacactagc tatcgtttca
    17821 atcaaccctt caatcataga ctgcttttga ccagcgctag agctcatatc agtttcatga
    17881 aactgtccta gggtcataaa tgccttataa taattgttaa catcgtttcc taaaataatt
    17941 tgatactgac cgttttggcg catgactcca atcacattag gaataagttt gattttttga
    18001 tctaccactt gtttatcatc tttcaaaacc aagcgtaacc gcgtgatgca gtgggttacc
    18061 tcttgaatat tctgctcacc accaactgct tcaaaaatgg ccttggctgt ttcttgataa
    18121 gtcatttcat tactccttca catttttgac taaacgtttg atatgaaccg ttaaatacaa
    18181 aagctcacta gagctaagct gataatggta tgcttttttc atgtgatggc taatttgcct
    18241 aacacagtga tattcctctg ggtatttatc cttaaccatc agcagcaaat cagtctcgtc
    18301 atcatcataa gccatgcctg ataacacgcg ctgagcaaat agcttcacat gagtgataaa
    18361 gcgataataa tcaatagaga cttcatcaag ctctgtctta aaatcagcct tgaccttctg
    18421 ttcaatgtaa gacacaattt ctgtcattcg atgaggctcc ttgaaaggat tatcaaggct
    18481 cgcgttgaca aagtgcatcg caataaacga agcttcatct acagccagag cgactcctag
    18541 ctcactggca atgacctcta aggccttaac gccaatcgca tattcatcag gataataccg
    18601 tctaatctcc cagcgcaagg gatcactaat gatcatcccc tgcttatgtc tttcaatagc
    18661 tgaatgaata tggtctgtca aattgatata gagtatttca tctaaatttt tacccagctt
    18721 aattttccct agattaataa gcctctctga gcaagcaacc acctcttgcg gaacagcaat
    18781 aaataattca gtaaaacggt tcatattgtc actatttttt aaaacaaatg acgcttcgat
    18841 agcttcacta tcgatatggt caccaattct tttcttaaaa gcaatcccct ttcccatcaa
    18901 aagaatatct agcccctgat ggttggtcga aatcgctgca ttatggttta aaacgcgttt
    18961 aataatcata aaagtcctag tccctcattg cttcacaata aaaaatgacc tatccacagc
    19021 atgctaaaag gccacactgg aataggtccc tgctcacaaa actgtgataa catcctttaa
    19081 tattctgatt catttgtcat tagcacgctt accctaagta atcacatcta ataacgtttt
    19141 cattttatca tctcctaaag gtcctgtcaa gcgttttcaa aaggctgttt gacatttgcc
    19201 tctaaacgaa ccccctcatt ctctttggcc aacagccgat aatctgaggc tttcctctta
    19261 aagtatgcct tctaatagtc ccttcataaa gtcctcagag tgaaattcac cgatatcatc
    19321 aatagcctca ccaaagccaa tcagcttcac tgggatatcc aattcctgac gaatagctag
    19381 gacaattccc cccttagctg taccgtcaat cttagttaaa atcaagcctg tgagcggtgt
    19441 gatttttgaa aactccttag cctgactcag agcattttgc cccgttgagg catcgagcgc
    19501 tagcagggtt tcgtgtgggg catcaggtat gacacgctta atgattcgtc ctattttttc
    19561 aagctctgcc attaggttgt ccttattttg caggcggcct gcggtatcaa tcaggagaat
    19621 atctgccctt tcagcaacag ccctctcaac gccatcaaag accacagagg ccggatctgc
    19681 tttttcaggg cctgtaatga ccggcacatc aacccgtcgt ccccattcaa ccagctgggc
    19741 aaccgcgcct gctcggaagg tatcagctgc aacaagcata accttttttc cctcttgctt
    19801 ataccgataa gctagctttc caattgatgt tgtcttacca acgccattca ccccaacaaa
    19861 gagcataacg gtcaagccag gctgataatg aatcgcttca ttgtagcggc catccccctc
    19921 ataaatagcc actagcttat caatgataag acgctttaga gcctctggct ttttagcatt
    19981 ttcaagctta gcctcatagc gcaattcttc agtcaaggtt gtggcaacat gaacaccaac
    20041 atctgagaga atcaaaagct cctctaagtc ctcaaagaag tcctcgtcaa cacgtctaaa
    20101 gttagcaaag aagctgttca agcgtgctga aaagcctgta cgggttttct ttaagctgcg
    20161 cttgtatttt tcctgatcag attcagctga tagggtctct tgcttttggc cttcctcagc
    20221 tggctgatca gctgaaccag caggtgcttg agctgctact tgatactcag catttgtctc
    20281 tgcctgatct tctgttgatg cgtctgcgct ctcgttacta tgctctgact tagccctatc
    20341 atgcttagcc tcctccatag cctcgtgctg gcttaggctc tcacctgcct gatccaaggt
    20401 cttgtcatca gtagctgcta actctagctc cggctctctt tctaaaagaa aagctcctct
    20461 agctgctgga tcaagccctt cagcttgctc tgaagcagcc tcgtctgaga gctcagcctg
    20521 tttgctagtg tcatcggtcc tagagaccac atcagctgcc actgcatgag catttgtatc
    20581 tgataaggcc tccttttcag actcaatcgt atcctttgac gttatgtcct ccgacaatac
    20641 ctctgtagtg gcagcctctt gctcagcaac cttagtctta tccttttttc caaataagcg
    20701 ttcaaataat cccattagcc ttcctcattt aaaatatatt tccaaatagc ctcagccaca
    20761 cctgattggt cattggttag ggtagtcact gcatctgcca cttccttagc ctgatcaacc
    20821 gcattggcca tagccacacc aagacctgcc cattgtagca tgctaaagtc attggcctca
    20881 tctcccatcg ccatgacatg cttggcctcc aagcccaagt gctgacaaag caggtccaaa
    20941 ccaaatgcct tatgaatccc cttaggcata atctcaaaga tgatgtctcg tgatttaaag
    21001 gcctcaaaat cctcaaagat agtctttgga agccttgcaa gctgctgatc caagaccttt
    21061 ggatccgtca ccgtaacaat tttattgtat gtgatgtcct ttggcagctc agcaaatgat
    21121 ttaaggctaa caaagttcag caagggactt gccaagtgat actgagagcg tctgccatca
    21181 ttgcctgata gactataaac agtaccatca ctgataacat cagtaggtaa gccaaccgct
    21241 gccaactgct gatgaatgtc ataaacctca gcaaggctta gagcgctttt atctaaaata
    21301 tgaccagtat ttcgttgaac cagaccgcca ttaaaggtaa tgctatagtt ctcttcacct
    21361 agcaaatcca gctcctcaag caaatttccg atagccttaa gaggacgtcc ggttgtgata
    21421 acaaccttaa ctcctttttc cttagctgct gctagagctt ttttgttctc atcactaacg
    21481 attttttcgg tattatagag agtcccatct aaatctagag ctaaaagctt tatacgcgtc
    21541 atttacacca atccctccaa ataagttaac actgctgagt cattacaatg accaataacc
    21601 tgatcagaaa tcgctttgat ttcaggcctt gcattttcag tagcaatagc ctgccctgca
    21661 aaggacagca tttgataatc atttagatta tcgccaaagg caatggtctt ttccggtaaa
    21721 atgcctaggt gctgacacag ctgatccatg ccaaagccct tatgaacctc ttttaggata
    21781 atatcaatcg aatcaaagcc agtcgtcacc gcagaagcat aggacagctc ctgatttagc
    21841 cagtcactgc cagctaagac tgtttctcct gtaaaggtcg ttgaggcttt aaaaacagtg
    21901 tcatcaacaa tatcctgcag acaatcaata agctgaacat tttcataata ataatgcatt
    21961 ttttggatat aatcctccgt agctcctttg agcacatagg ctgccttttg ccctgaaaag
    22021 aggatcccag actgattgta ataaggattg gcaagaattt tctctacaat gtcatgacac
    22081 tgctgcttgg tcatgacatc agcaaaaaga atgtccctct tgtattgcac cacagaccca
    22141 ttctcagcga taatggcaat gtcatctaaa aaaggctcaa acaagtgatc aatggctaaa
    22201 agcgaacgcc cactagaaac tgtaaagaga atcccttttt ctcttagctt aggcaacaga
    22261 gctgccaagc gctccttgtc ataagttccg tcctctctta aaaaggttcc gtccatatct
    22321 gttgctatca atttaaccat acaatttaac catttccttt ttagggagat actgattcag
    22381 ctattcagct ctcccaaaaa tctctttttc cattatacca tatctaaaca aaaagggcgt
    22441 gcctgtccta acacgtcctt gttttaaggc tttataattt ctgtagtggg taactccact
    22501 gtggagatta ttgagccctt attccaaggc tttctttatg ttctattgta tcaatttcct
    22561 tattccaatt tctgttgcaa ttaactttaa catacaatct aaccatttca ctttcaaggg
    22621 agtgcaaaac ccgagtgggg tgtgcaactc aaatcccagt ataactcctt tcgttatacc
    22681 acaggtagac caaaaaaggg cgtgccatct gacataccct tgttttaaca gtcaatctga
    22741 gctccgtttt taaaggctaa acttctttat ctccatactc tcaacgctta tttgccataa
    22801 ttcttaattg aagcccgtca ctaagttttc ttgttactaa agagttgagt aatgaatcta
    22861 tctagactga tgatttttct ccttaaaagc ttcatatagt tttttatata acgctttctt
    22921 ttcttttttc tgagcattaa actctttttt accgtaatca aaatttgcta ccacaaaccc
    22981 cttgttattg ttagaaaaat caaaaaattc catttcgatt aatttgttat tcttagaatc
    23041 ttctatagta ttctctaaat gattgttgaa ttgtttaaca tcttcttcac taactccaaa
    23101 acccatagca gctccgtctg caatgatgtt tgaaaatatt tcttctgaag atgctgcttc
    23161 ttttaccctt attaggtata tggcttcttc tgtttctaat tgtcttactt tattccattt
    23221 ttgggtatca ctagaagaga tcgtatagac tgttaaatct accgtaggtt tattgggatt
    23281 ttcttttttt attacttgtt ttcccactaa gaaaattgcg agtattccaa ttaataatat
    23341 caacgtcata taagctttct ttttcatatc tcactcccta tatctttcaa atcaatgata
    23401 acatcaacct tattatatac agctggatca tgtgttgcta taataacata tttattttcg
    23461 gctgtttcac tcaataataa attaatgatt tcttttccaa tctcactatc caaagctcct
    23521 gtaggttcat ccgctaaaat aattttacgt ggcttcatta acattcttgc aatagctaca
    23581 cgctgaacct gtcctccaga taattcatat attttctgat ttaaatagtc attagaaagt
    23641 cctacttttt caagtacatc agctattatt tttttatctt tattgatgag tctcaaatta
    23701 tcatatactg ttttgttttc tattaaagaa taattctgga atacataccc aataatagtt
    23761 ttaaagaaag ttctttcttt tgtcttccaa atatcctgct catcaactaa aacctttcca
    23821 ctgtcaattt tttctagtct tcctatgata ttaagtagtg tacttttacc tgaaccagag
    23881 cctccaatca atgcgtagct ttttccagct tcaaacgtta aatttaaatc tgtgaatatc
    23941 ttttttgagc cgaatttttt ggtaacattc aaaacttcaa ttgccattag tcatctcctt
    24001 ttagaatttg tgtatatttt tcagataatt ttctaaaact cattattgtt gaaaaaatta
    24061 aaaccattaa agaagcaatg ccaatatata atagctctac ttgtcctgtc aacataaatg
    24121 tcaatagaat aaccattgta atagtcacaa taaaatagtt gagacttgaa atggctatac
    24181 gtgttttcga taggcctaaa atgatttttt taacatagtc attctgtttt aaggcaacaa
    24241 acatttgagc atactgataa atgagtagaa atacgattcc acaaataatt atttgcagta
    24301 tttttgaaag gaaaatttga tgctctaagg attgaatatt aagttttaca gtttggtaaa
    24361 cctcgactgg attgattgaa aaattcaaac tagcactcaa atcgttgatt ttcttaattg
    24421 cttccgaact aaaaagtgag ttatatatta tattacttgc caaaataaaa tcgttatttt
    24481 ctatcatttt atcagtatct agcacaacga ctatattatc cttactatct gtcacacttt
    24541 ccaaaggtag attatcttta ttttcaggaa cactactacc attttcattg aaatagaaaa
    24601 attcttgccc atcaggaatg acttgcaccg taaggtcatc ttttgtatag tttgtaccag
    24661 taaattgttc tgctacaact gtattctcga ttgatgcctt attctcttta aatttatgag
    24721 gaatatagat ggttgctatt ttattatcta atgattgata gttcgttcca ttaactttat
    24781 tttgtacctt agcacctgtt tgattaatat aaaccagttc cttattaact tctggatgcg
    24841 ttattccatc actttttaat tgcttagaaa aatcttctgt aacatcagaa gctgccatat
    24901 attctggaac ataggctgaa gatgatttga tatatataaa atccagtttt tttaaggctt
    24961 tagcaatctc tacgtactta gctcctgagt catttgcttc ttctccatta gtaacagatt
    25021 cattttcaat acccaaaaac tctggtcttt tccaatcttt tactgcactc catggtttta
    25081 aatgctttat ctgcatgttt atctttgatt gactagcctt tgtttcccgt aaaaagactc
    25141 ctgaaacaac tattatgata gaaataaccg caagccatac gataaaaatg aggctatttt
    25201 tggccttatt ttttataatt tcaataggtt tttcaacctt aatagttagc caaaatagaa
    25261 caaaggtgat gatgtcaatg atttgaaata tgatcaaatt agttaaaagc atagaaaaaa
    25321 ataacttgga actgtaggtg aaaaaaccac tacccaaaaa agaactataa gaaatcatca
    25381 ataaagcggc cataaccagt tcaaaagtaa atgacatgaa ataatctctt cttaggtcgt
    25441 gtacaggtaa tcctaaagaa cgtcttatca ctccttcttt aatctgtctc gctctaacaa
    25501 caaatagaac aactaataag gttaagtaaa ttgaaatcat tagcaataat ctcaacggac
    25561 cagtaaattg tatcattccc cctatctgcc aagggtaagc cagatatatg acttgaagac
    25621 ctgtagatgt gagcggtttt aaactatttg aatctaattt ccctagggta taatacatcc
    25681 ctgtgattgg tgcagacttt aattgttcat gattagtatt atcaaacttg atataagtca
    25741 actgccccga attttgaact accggtttgt aaatggtaac ttttttctct tttgataggt
    25801 cactaatcgt ttgatacact tcttcattag aaagattgct tttcccttga atggagaagg
    25861 caccatcaat tggtaaaggt attggttttt gagtatcatt aatactaacc agaccaatgg
    25921 cagcaattaa acaaaagaag aatccaacaa tgcataattt taatttcata agcacctacc
    25981 tatatcataa aaggccctat agcattattg ggcctttagc tttcataaac catttttaaa
    26041 atgtaaagta attccaatgt gtatttaatc gaacatcatt ccagcttttt gttgcgcttg
    26101 agtttgccca tccatatttt tgagaatctc tatccttaac tgttccccat agattagtta
    26161 ctgaagattt tgaaccaata ttatttggag acttaacata gtcattagaa taaccatagt
    26221 tatcacttac accataattc cattcatcaa taattggata tggagctgga tgcgctgttg
    26281 ctgcactaac aactctagct gtagcagcag atccaaaact taaagtgctt acagcaagca
    26341 aaactaatgt tttgtcacca atttttcata ttagttctca ttggatagat tgttaaaaat
    26401 atttgaacaa tctaaataat atattattat ttattagcat aatatcatat tattatttga
    26461 attacaagat gctaaattgc aagtaaaagt tagtcatcct atagaaatta tccgagtgac
    26521 ttgttgttca aaattttccc caattttaaa aagagatgaa actctgcgtt ggattgatcc
    26581 tttaagcgac ccaattcatt gaaaaaatct gatgcagcat tggcagatag gtctaaacgc
    26641 ttcaaaaaaa cactcatctt ctggtactca gagttgatca aatcatttaa gacatgtctt
    26701 ctttcagata agctgtcttc acgcttctga taggctcttt tctggcgtag aaagtcctgc
    26761 tcggcatcat ccatctcccg aagcttacga taaatagcca cttcctctac aattctgtct
    26821 gccatgctct aaactctcct gctaactgac gatccgtttc aagcttgcta tcaataaccg
    26881 tctgaatatc tctattcaag ttttcaaagt ctgtggccaa ggctgacagc ttgctgacct
    26941 tggattgagt atagtcctga aagtcttgga caaagcggtc atatgtgata ccataagaag
    27001 caaataaggc ctgcacctca tagtagggca gctcatgaaa agagttgaag tcaatcgccg
    27061 accacacttc cataagcttt gcgtctgcaa ccgttttatg atccagagct tcatcagccc
    27121 cctctcgagc agccttagcc atggacgagc ctaggatcat tccctgtgcc gcatctaaaa
    27181 agagctcctc agaactactg atccccttgc cggtagactg ccagtgtttt ttgagctgat
    27241 tgtagcttga catgctcttt tttgaggcaa ggacagttaa ataggcccga ctcacaaggt
    27301 attgtgttcc aatgagctta ccgtctctat ctacaatctg acccttttga ttaaaacgat
    27361 aagctcctaa atcgtgataa tacaaggggt tggctgataa gagcatagca tcgacattcc
    27421 gagaaatagc taaatcatca gttccaaaat aggcaccaaa attgccaatg ccatcaaaat
    27481 taatgcggaa attattgtac atattgctat tagccttaac ccatgtgata gcttcagctg
    27541 acatgccgcg aacagggtct ggaccattaa aggttgttgc tgggatctta tgttctgcgg
    27601 caactattag tgctagataa gctccgagag agtgacctgt ggttgttaag gcagaatgag
    27661 ggtactttct tttgacctgt tgataaaact tttgagcaga tcgtaattgg ttttcggcaa
    27721 taacaaaatt gccaccatca atattgccgc tgactaaatc atcttgattg ccccgaatga
    27781 gcagctgcca atccgtatca agatctctgg aatccgcagc atttgtccct gcataggcaa
    27841 tcacaacctg agaggtatcg atatcacctt taacaatagg ggctacagcc attgcctgca
    27901 taccgttgtc attggtttta tgggcatcgt tgttattgtc ctgaactaag aggactcggt
    27961 attgtcgttt agtgatagga tcttttacag ttttaccagc aacaataaca aggtctccat
    28021 ttgatttagc tttgctaggt tcgacattat aaacctgttt agccaactca ttataactac
    28081 tatccgatat cgccatatta atcctcctga ttgtcctttg aataaatgac agtaacacct
    28141 acaagagatg ttttattaat cttgtcaatc ctatccataa ttcttggttt ggtatcagtt
    28201 tcaggctttt ccatcttttc tgtatcatca tcagtaacaa ttcctcgtat tttctcaaga
    28261 ctagacaagc catcaaacga aaagcctatt tcattttctc catttataat cactatcgtt
    28321 ccccacgaac ctgtttcccg agaatgtccc cagcctgtaa acttaacttc tttaacccct
    28381 tcatagtcat gaaccagcag cttagcaata ctggtttcca agtccctttt ttgttgttcc
    28441 tctgttcttt tgccattcaa acgaaaaacc attatgatcg ctcctattac tattattaag
    28501 cctagccata gcctttgctt attggtctta actgtcatca tgtcctcctt tcactctttt
    28561 gctatgcgtc cgtcactcta aggaaggcag catgactaat tagggtgaaa tcaacgccaa
    28621 atcttattta tattattctc attttgtaat taaattataa tatacagaca tctacttgtc
    28681 aatatattat gtccttagtt acttttttgg tatattttaa tcaaaacaag ccgtactaag
    28741 ttccaggagc atgtcaaaaa cagcagctta ctgctagcca atccttgtgc tttgtccttt
    28801 ggaaagccaa aaaacctacc atgacgatag gtttttttat agcttattct tggttatcat
    28861 ctgctacatg tagaaataca gctaaaacta agctctgtcc tagagttatg acaagtaagt
    28921 cagatcctgc gtatccttga gcttaacaga tactacctta gaaataccag attcttgcat
    28981 ggtaatccca taaatactgt ctgctgctgc cattgtcccc ttgcggtggg taaccacgat
    29041 aaactgacta tccttgtcaa aacgattgag ataatctcca aaacgcttga cattggcctc
    29101 atcaagggcc gcctcaacct catctaaaat cacaaaggga atggtcttaa tgcggataat
    29161 agcaaataaa agggctagcg ctgataaggc tttttctccg ccagacatca cattcaaaga
    29221 ttgaagcttt ttaccaggcg gttgcactga aatatctact ccagcagaaa gcagatcagt
    29281 ctctgtcaac atcaagtccg ctgagccccc gccaaacatc tgcctaaagg tctccttaaa
    29341 gctatcacga atagcctcaa aggtaaccct aaagcgtgcc ttaacctcat ggtccatatt
    29401 gccaatcgta tctaccaaga gattcttggc cttgataagg tcagcccttt gaccatttaa
    29461 gaaggccaaa cgctcactaa cctcatcaaa ttgagcaata gcatcactat tgattgggcc
    29521 tagggcacga atgctttgct gaacctgctg caatttctgt cttgctgctg ccatgtcagt
    29581 gtcattgatt gggcttgcct gctccttggc ctcctctaag cttagctgaa gctcctctga
    29641 taggcttcta gcgtgctgcc gcaaacgacc aataacctgc tctaagtcag cctccagtct
    29701 tgcctgctga cgaatgaacg cttcattttt cttggcttcc ttaagcaatt gagcctctag
    29761 ctcctccagt ctggcgtcat agtcctcacc ttcaaagcgc agctgaatga agcgctcctg
    29821 agtcttgatc ttgtcttgat tagcctctgt cagctgattt tctaggtgag gcaattggtc
    29881 aatggcctcc tgactaacct gatgtgataa aacagtctcc aaattagcta attccttctg
    29941 accctgagca atcatcgtct ccaagcgacg ctggttagct gcttcaaact ttttctcgtt
    30001 gagcaaatct cgctctttaa gacgagcctg agataattcc tggctaagct ggtccttctt
    30061 ttgcttaatc gtatctttat tttccttaat ttgctcaatt tctgacgtta aggctgattt
    30121 ttcatcagct aggagctgca atgcctcctc cagcctcgct ttttctgata ataagcgctc
    30181 actagactga ccagtctgac ggttgctgag aagctctagc agctcttttg agtcagccag
    30241 cttttctgct agctgctgat aggccaattg tgttttttgc tcgaccagtc ttgcttgctc
    30301 accagccagc ttagtatcag cctgcgcagc ctttttagcc ttcaaatcag cctgtacagc
    30361 agctactgct ttttcagatt ccttgatctg ctcagaaagc aaggctaatt ccttctcaat
    30421 ctgctctagc tctggcttga taaaggttgt gctattgtga cgattagtcc cccctgaaaa
    30481 ggcaccaccg ggacgcagct cggtaccatc aagcgttaca atcctgacct tataatgcag
    30541 ctgcttagct gcctgattag catgatcaat ggtatcaaaa atagccgtca cacctaacag
    30601 gctttgtaca atagcgacca aagagggctc ataggtcacc aaagaatcag ctgtgcctaa
    30661 atagccctga caagccctga gctgcttgag agtcacctca gaaagctgac gggccttaat
    30721 cgttgtcaga ggtaaaaagg tcgcacgccc ctgacgatta gcctttaaaa aggctatcgc
    30781 tcgcttggct gctgcctcat ctgccacgat aatatgctga ctactagctc ccaaagcaat
    30841 ctcaagtgcc gtttgatact gactatcaaa ggtcaaatgc tcactaactg ctcctaaaat
    30901 accatctagc ttaccagcag cctgaagcac tgccctaaca cctgcgtaaa attgactatg
    30961 atttttttgg atagaaacca aactagccct acgagcctcc ttggcttttt tctgatccaa
    31021 caaatcaaaa agccttgtct gtccctgatg ataatcctgc tccaaggcct caactgtctt
    31081 tgctagctct tgataatcag ctaggagctg ctcaagtctt gattgactag cttgataagc
    31141 caaaagagca gtctgggtgt cctgactgag ctgattgacc ttctcttgta ggacttggta
    31201 ttcctgcgcc tgactggctt tcgcctgact ttccttatcc agctgcgcta caatagcggt
    31261 taattggttt gacacatcag cctcttgctg gagcagacca acaaaatcct cacgaagagc
    31321 ctcaagcagc tgatctggat cgctagaaaa tcgctcaagc tcctgagaaa gctcgctgac
    31381 cttggtatta aactcagcta aggcttgatg gatttcatct agctgacgac tcttttgctg
    31441 atgctcctgt tgaaaggcaa gcaattgctc ctgagcctgc tgcctgcgct gactggcttc
    31501 tgttttcttt tcctgctttt gactaaggtc cagcttgatg aggtcaatct gtcgctccag
    31561 atctgatatg acctttgtca attctagcaa atcagcctgc gtctgctcag ctacagcaga
    31621 gagcttttgc cgcttggttt ttagacggtg attttccgcc tctagactct gacgcttcct
    31681 atgataggcc gctagatcct cacgaagagc tactaaggcc ttttcttgag cctcctgctc
    31741 catgcggtct tgctctatat ccttgaccaa aatatccagc tgcagctgct tacgatcagc
    31801 atctaaggct aaaaattgcc tagcagtttt cgcctgtctt tctagaggac cagcttgatg
    31861 ctcaagctca tagataatat cgtctaagcg gtcaagatta tcttgagttt ggtttagctt
    31921 agtttgcgtc tccttcttgc gggtcttgta tttcaaaact ccagctgcct cttcaaagat
    31981 ggcccgtctt tcctctggct tactattgaa aatctcctca acacgacctt gagaaataat
    32041 agagaacgaa tcgcgcccta gtcctgtatc cataaacagc tcgtgaatat ctcttagcct
    32101 aacttttttg ccatcaatca gataatcact gtcgccattg cgatagatat gcctctccac
    32161 acgaatctct ttctgagcat tcttaataaa ggcatctgaa ttatccaaga caacagccac
    32221 ctctgcataa ttcaagggac tccgatgctc agttccagca aagatcacat ctggcatctt
    32281 gccaccgcgc aggcttttgg cactggcctc accaagtgcc caacgaaggc tttctgtcac
    32341 attacttttt ccagagccat ttggccctac aacagctgtg acccccttat caaagataat
    32401 cttggtctta tctgcaaaag acttaaagcc ctgcatttgt atttctttta aaaacattta
    32461 gacctcacta agttgggcca gggcattttt agcagcgtcc tgctctgcca gttttttaga
    32521 tctacctgtc cccttgctaa gatgatcctc accaaccaat acagctacct caaattgctt
    32581 agcatgagct ggtccagtct cgctaatcac ctgataatca atcacaacat cacccttagc
    32641 ctgtaacaac tcctgcaagc aggttttata atccttgacc ttctcaaaag ttccctgctc
    32701 aacctgtgga atcataacct gatttaaaaa gcgacgaacc tcttcaatgc ctttatccaa
    32761 aagaagagca cccaaaaaag cctcgaacaa atcgcctaaa atcgtatcac gatgacggcc
    32821 tcctgatttt tcctcgcccc tgccaagctt aatataagca tcaaacgaac aatagcgtga
    32881 aaagcctgct aagctttcct ctctgacaat cgttgatctg agttttgaca tatcaccctc
    32941 agtctgctta ggatacttgg caaagaggta ttctgaaata attaactgta gaacggcgtc
    33001 tcctaaaaat tccaaacgct cattatgtga aatgtttagg aggcgatgct cattagcata
    33061 agaggtatgt gtaaaggcag tctctagtaa tcttttatca tcaaaacgga tattaaaaga
    33121 gttttccagc agggcctcaa gctttttcat catgacaaat ctccttttct aatgtcctta
    33181 taaaccattc tattataaca aaaatccact tgaaaggctt atcacaagtg gatttttcag
    33241 aaatattgta ccaaataggc acgagctatt gactgctgct at
//
LOCUS       DARYLJ010000022        33230 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYLJ010000022 DARYLJ010000000
VERSION     DARYLJ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33230
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(310..909)
                     /locus_tag="TU746_000942"
     CDS             complement(310..909)
                     /locus_tag="TU746_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL0891299.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            complement(1487..3433)
                     /locus_tag="TU746_000943"
     CDS             complement(1487..3433)
                     /locus_tag="TU746_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0891300.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TU746_000944"
     CDS             complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TU746_000944"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL0891301.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            complement(4338..5051)
                     /locus_tag="TU746_000945"
     CDS             complement(4338..5051)
                     /locus_tag="TU746_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0891302.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            complement(5486..6409)
                     /locus_tag="TU746_000946"
     CDS             complement(5486..6409)
                     /locus_tag="TU746_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL0891303.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            complement(6421..7479)
                     /locus_tag="TU746_000947"
     CDS             complement(6421..7479)
                     /locus_tag="TU746_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL0891304.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            complement(7611..8603)
                     /locus_tag="TU746_000948"
     CDS             complement(7611..8603)
                     /locus_tag="TU746_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL0891305.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TU746_000949"
     CDS             complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TU746_000949"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL0891306.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TU746_000950"
     CDS             complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TU746_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL0891307.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(11117..11356)
                     /locus_tag="TU746_000951"
     CDS             complement(11117..11356)
                     /locus_tag="TU746_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL0891308.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TU746_000952"
     CDS             complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TU746_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL0891309.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(12069..12686)
                     /locus_tag="TU746_000953"
     CDS             complement(12069..12686)
                     /locus_tag="TU746_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0891310.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(12679..13902)
                     /locus_tag="TU746_000954"
     CDS             complement(12679..13902)
                     /locus_tag="TU746_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891311.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(13914..14624)
                     /locus_tag="TU746_000955"
     CDS             complement(13914..14624)
                     /locus_tag="TU746_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891312.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(14624..15886)
                     /locus_tag="TU746_000956"
     CDS             complement(14624..15886)
                     /locus_tag="TU746_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL0891313.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TU746_000957"
     CDS             complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TU746_000957"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL0891314.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TU746_000958"
     CDS             complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TU746_000958"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL0891315.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(20909..21844)
                     /locus_tag="TU746_000959"
     CDS             complement(20909..21844)
                     /locus_tag="TU746_000959"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL0891316.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(21902..23161)
                     /locus_tag="TU746_000960"
     CDS             complement(21902..23161)
                     /locus_tag="TU746_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL0891317.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TU746_000961"
     CDS             complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TU746_000961"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL0891318.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            24060..24674
                     /locus_tag="TU746_000962"
     CDS             24060..24674
                     /locus_tag="TU746_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0891319.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(24755..25645)
                     /locus_tag="TU746_000963"
     CDS             complement(24755..25645)
                     /locus_tag="TU746_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0891320.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(25635..26093)
                     /locus_tag="TU746_000964"
     CDS             complement(25635..26093)
                     /locus_tag="TU746_000964"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL0891321.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(26321..27250)
                     /locus_tag="TU746_000965"
     CDS             complement(26321..27250)
                     /locus_tag="TU746_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0891322.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TU746_000966"
     CDS             complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TU746_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL0891323.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(27972..28304)
                     /locus_tag="TU746_000967"
     CDS             complement(27972..28304)
                     /locus_tag="TU746_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL0891324.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TU746_000968"
     CDS             complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TU746_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL0891325.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(28665..28739)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(28861..30054)
                     /locus_tag="TU746_000969"
     CDS             complement(28861..30054)
                     /locus_tag="TU746_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL0891326.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            30319..30936
                     /locus_tag="TU746_000970"
     CDS             30319..30936
                     /locus_tag="TU746_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL0891327.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(31234..32463)
                     /locus_tag="TU746_000971"
     CDS             complement(31234..32463)
                     /locus_tag="TU746_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0891328.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(32498..33190)
                     /locus_tag="TU746_000972"
     CDS             complement(32498..33190)
                     /locus_tag="TU746_000972"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891329.1"
                     /translation="MSENSDIEEAINMIRNDIYSYHFQCTYKLNTNIAISDDWNQELV
                     NIISLQDTLITKYNKILDKSDEVLMQLKSEVNLGLNGLAGVLFYLSSISYDNEIIEKG
                     IDFILESLVEDSDGNRGVLISENSVSPYLSNGTAGIVQLLIYVNSDKYIKDIKNLSES
                     LLVEFAQFSGLWNGMLGIAMTLLQVFRLTNDTLYLEKACELLISSKIMSEHHIKLQYE
                     FRYAVSIFNQVK"
BASE COUNT        10050 a         7691 c         5901 g         9588 t
ORIGIN      
        1 aatcaaaaga agatagcatt tctgctatct cactgttagc cactacttac aggtaaaaat
       61 acaccttgtc tatttgtagt ttaactatcc atttaatcca tcaataagcc aaaccagacc
      121 gtttaatcat ctacccagcc ttacacatag tattttctca catcatttgt agaattgctt
      181 tctccttgca tgtcaccatc tcgtcttaaa cgttcgtaaa gggctgtttg atcttttcta
      241 actattttag aaaattattt tgctgttctg atgaggttaa tctcgttaga tcagtcatgc
      301 tggaggtagc taccgtatgg gagcgtcaaa ataagtcagc tgataatccc ctataatacg
      361 attgagcttt tcgccatagc tagtatctgt ggcatatgtg cctgttaaac tagcggtggc
      421 ctgctgataa cttgtatgaa tacctcggtg agtagggcga taaagcgggt cactcaaaac
      481 cctagcataa tcctcaaagc aggctgttaa gctgccatag gaccgaaaag aagcgtcaat
      541 tagataaagg ttgccttggc catcatcttc caaggtaggt aaaataactg attttccttt
      601 atagcttcct ttgataccaa aaaaattata atagggctct tgacttagct tagattgacc
      661 atttgctgac tccaaaatag cctgtgccat catgactgag gcatagagct tgtttcgctg
      721 cgcaactgcc tgagcggaat gactaatctt gctcacaaat agcatggttg agctattggc
      781 atgaggctta aggtgatcct tagctgacgc taaggtccaa aggctaagca acatgctgcc
      841 taaaacaata ccagcagcca gccaagagct agcttccctg tggcttcttc tagctttcct
      901 cctcttcaac agaaatatcc tcacttcctt gcttttaaac ctagtatagc aaaaattaaa
      961 agcaaaatgt agccagacca catgctcacc tcaaaaacag gccttatgac ttctaaaaag
     1021 acctagcagc cacaacaggc gcataaaaag tttttaacaa gaaaagaaga ctttgctgta
     1081 tttcaatcca cgctcctgca aagggagcga tacaaaaaat aaatggaata tctacaatca
     1141 aatgatttca atgtttagct atttcaagaa tatatcttat ttttgataga tgttactata
     1201 ggaaaaacgt tgatagtatc tactttaatt gatactataa ttcgaaaata actgtttcgc
     1261 acgtttggtg tggcttagtt tagcagggct attgggtcac tgcttagcta ttctagatca
     1321 gattgattct ctctaaatat tagcttttcg ccagtcatca ctactagcaa caaacaaaac
     1381 gcacgacatc atgtaaaaac aggctgatgt catgcgtctg atgttttatt aagactaggt
     1441 ctaattcaga agctttccct agtacttgtg gctttatagc cagtaactaa gcttttttac
     1501 gaagtgcgcc aaagagaata ccagaaacca ctgctccaat agcgacaaac aataggtata
     1561 agaaaggatt gcttgtcaaa gcgataacga agataccgcc atgtggtgcg attaatttga
     1621 cacctgctag accaacaaga gcacctgtta gggcagagcc agcgataaag cttgggatag
     1681 cgcgtgctgg gtctgctgca ccaaacggaa tggctccttc tgtaatgaag gaaagtccca
     1741 taataatgtt ggtcaagcca gattcacgct cttccttggt aaatttgtct ttaaataaga
     1801 gtgttgccac aaaaacagct agaggaggca ccataccacc tgccatgaca gcagccataa
     1861 caactgaccc accgcttgca acggttgcag caagtgttcc tgtaccaaag acataggctg
     1921 ccttattcac tggaccaccc atatcaacag ccatcatgcc gccaacaaga agtcccataa
     1981 gaactgcaga gctacctgac agactttcta agaagtggtt caatgctgta ttgatagctg
     2041 ccataggaat attgatcagc agcatcaaaa gacctgtcac aagaacacca agtaatgggt
     2101 aaagaaggat tgacttgacc ccttcaagcg aacgcggaag ccctgcaagc acttgacgaa
     2161 gagcaagaat tactccccct gcaaggaagc cacctacaag cgcaccaaga aatccagacg
     2221 gtactcccgc taatgatagg ctagcctcac cgccagcagc aaatggaacc tttccaaaag
     2281 caagaccgct agaagcaatg gcacctgcca caaagcctgc cacaagacct ggcttttcag
     2341 cgatagaata agcaatgtag cctgctagca ctggcaacat gaatgaaaag gccgcaccac
     2401 caatatgttt aaagatagct gctatttcat ggtaggatcc caaattagac agctgatcct
     2461 ttggtacccc aagcatgttg tcaagcaaga aggcaagagc aattaggatt ccaccaccaa
     2521 ttacaaatgg cagcatttgt gatacaccac tcatcaggtg cttgtagaag gctccgccta
     2581 ggcttgtctt ttgagctgct tttgcttgtt cagcagcgcc attcttggca tgataaacac
     2641 taccagcatt gtttaaaatc agtgaaatca attcctcgct tttcttaata ccatctgcta
     2701 caggacgagc aatcaattgc ttaccatcaa agcgatccat ctcaaccgcc ttatcagcag
     2761 cgataatcac tcccttggcc tgcttgatgt catcagctgt caggcgattg ccaacccctg
     2821 aagcaccgtt ggtttcaacc ttgatgccga cacccatctg tgcagcctgc tttttcaagg
     2881 cctcttctgc catataagta tgtgcaatac ctgtcgtaca agctgtcaca gcaacgataa
     2941 actcctgagc atttgtagga acaaaagcta cctctttctg atcagaagcc gcatcaaaga
     3001 cagcaatcac ttcgtctgga cttgttgcct ttcgcagttg atctgcaaag ccatccttta
     3061 ataggtattg ggataattcg gctaaggccg ctaagtgagt atcatttgcc ccttgaggtg
     3121 ctgcaatcat aaagaacaga tcagttggct gaccgtctaa ggatttgtaa tcaacgccct
     3181 tgttagattt tgcaaagagc actgctggct ggtcaacaac aacatttttt gaatgcggca
     3241 tagcaatgcc atcgccaaga cctgttgagg tttgctcctc gcgagctaag atactctttt
     3301 taaacacatc aaagtcatgt acaatcccat gctctactag ttctgtaatc atttcatcaa
     3361 ttgcagcctc ttttgaaaca gcctgcaaat caagaatcat gatgtctttt cttaataaat
     3421 cctgtatttt catcgaacct ctacctcaac ctcattatat gtttttttaa tatcatcaat
     3481 tgctgctaaa tcatctgaaa aagcagttgc tgttccgcag gccactcccc attttagagc
     3541 ctctagcgga ctatgacttt tgacaaaggc acctgtaaag cctgccacca tcgaatcacc
     3601 agctccaaca gaattcttca cctgcccttt aataggctta gcaaaataag ttgcttcctg
     3661 agtgaccagc aaggcaccat caccagccat cgaaacgata acatgctgcg ctcccatgtc
     3721 aaggacctta cgagcatatg tttcaacgtc atctagccca tttaagctga cgttaaaaat
     3781 agcttctagc tcatggttat taggctttac gagcaatggg tgatacgcca atgcatctag
     3841 caaggtctgt ccttcaaaat cacagaccac ctgtgcccca gcttgtctga ccaatgggat
     3901 caagtcctta tagacatcat tgcctagact tgaaggcgct gagcctgcaa aaacaacaat
     3961 gtcctctgct gacacatttg ccaatatagc ctttaaatga tccaattgct gctttgaaat
     4021 cactggtcca aggccattaa tctctgtctc ctctgctgat ttgatcttaa cattgatccg
     4081 cgtatcctga tcaaccgtta caaagtcagt attgatgctc tcagcagcta gactttcctt
     4141 aataaaacgc ccagtgaagc cgcctaaaaa gccagtcgct gtattatcaa tgcctaatcg
     4201 ctgtagaatg cgactaacat taatcccctt tcctcctgca aatgtatcgt cactgaccat
     4261 gcggttaacc gctccaatat ctaattggtc tattctgaca ataaagtcta tagaaggatt
     4321 taaggttact gtgtaaatca tagtgcaatt accttcgctt tttccttgat tttcttcagc
     4381 attactgtcg aagatttctc tgtaatgatt tcaaccctat caattggagc aaccttgaca
     4441 aaggaaacat gaccaagctt tgttgcatca gctaatacat aggtgatttt agcattggca
     4501 atgacagctt ttttaataac agcctcctcc atatccggag tggttaaaaa tgcctcatcg
     4561 ataccattga taccaagaaa agccttatca aaattcattt gcctaatttg ctccaaggca
     4621 acatgaccga tgcttgcgtc tgttgtctgc ttgacatagc caccaataat aatggtcttg
     4681 atcgccatat caaccagtct agtcgcatga tgaatagaat tagtcactac tgttactttt
     4741 tttaattgca aaaaaggaag gagaaattcg gttgttgtcc cagcatcaat aaagatgaca
     4801 tcattatcaa aaaccagctc tgctgccttt tgagcgatga tttcttttat ttgactgttt
     4861 ttgacagatt tttcctgatt agataattcc tcttgtaagg aatgaaaaag ctcggcacct
     4921 ccatgcactc gatgaagctt gccctcacgc tccagctcat ctaaatctct acgaacagtt
     4981 gattctgacg agcttaacag ctgcattaaa tcctctagcg caacgtaatt ctcagctgtg
     5041 atttttgcca taatgagctg ttttcgtttt gattttaaga taaaaccacc cctttgtctg
     5101 aaatcgttta cagctctatt atactacact ttattccaaa gtcaagcact atctttcaaa
     5161 aacattcaaa ttcaatctta gacctctatt gccttaacaa taactgccaa ttgatcagtc
     5221 attgtccccg tcaatacctg tagactaatg attaacgact tttttattaa ctagagccca
     5281 aaaagcgctc acctgttgca aaagtctgaa acacaatagt ctcttacaaa tcaaaaagca
     5341 acggatttac tgtcgttgct tcataatgag agtctaggac aaagtctttt cagccaacaa
     5401 gacaaaacga gagagtcacc tattgtgagc ctctcgtttt attgtactga gaaattgttt
     5461 tatcccagac tccttatgtc taaacctatt tgatcttcaa aatattctct ttggcatgga
     5521 ctagctgtgt aatcaagcgg caataagggg tatcgatacc aagcttttca cccttggtat
     5581 ttaccgcacc gttgataaag tcaatttcag tcaagcggtg attttgaaca agatcctgat
     5641 gcattgatgg gtagtgatga gcagccttca ctgaggtttc catcacatag gctgtgattt
     5701 cctcttcatt aagctccacc ccctcagcac gaccaacaat aacaaactca tgaatgattt
     5761 ctttaaccat gtttaaacca tcttcgctgg caaataactc accaatcgtg caatcaagta
     5821 gggcacaggt tgagttcatt gtaccattga cacaggcttt tctccaaata tttggaacaa
     5881 cattatcatc ataagttgca ttcaattgag cgtcatttag caagtcagca atctgatgtc
     5941 ctgcctcttg gtttgctgga tccatgcttt gtagattaag cgcaccaact ccttgtaagt
     6001 gtacctgacc aggtccctca agacccgctg tccaaacggt aacacccatt aaaatattat
     6061 gctctggaat atagtgacga atcacatctt cgtgtccaag accatttaat aggcaaagta
     6121 ccttggtttc agggccaata atacctttaa tatcagtcag catttgtggc agctgcatgg
     6181 ctttggtaaa caaaatgata aggtcagctt ccttagtagc ctctgtcggc ttcatgatag
     6241 gaagctttac ggtttcctct acatcgcctg aaatcttcaa gccattctct ttgatcgctt
     6301 gaagatgtgc ttcccaatta tccagtaaaa taacgtcatt gtttgttttt gaaatttggt
     6361 aaccaaatcg acagcccata gctcctgagc ctgcaatata aactaacatg ctttttcctc
     6421 ttatccttca aatacaaaaa tatcttcttt ataaagcttt aaaatatcct tacaaagctt
     6481 atgtgccaca aaagcaactc caaatggaat gaccaaccaa gcaatgataa tgatcacaat
     6541 attgctgcca ccggcaagtg aagcaatagg accaactgca ccaacaagac caaagccaga
     6601 tgaggctggt gttccaatca gattaaacat tggaacggtt aaagagctaa caatagctgt
     6661 catcatcatt ggaatagcca taactgggta ttttaagaag tttggcatca tcattttcat
     6721 agcgccaagg gcaatggcaa ttggaacacc tgatttgtta acctttaacg ttgcccacac
     6781 aagaacagcg gttgttgaag caatacccat tgaggccgca ccagctgcca taccatttaa
     6841 gccgatagct aaaccaatcg caaccgttga gatcggactc acaatcaaaa gagcaaaggc
     6901 aatggcaatc aaaatagaca tcagaattgg ctgaagcgtt gtaaatgaat taatgccttg
     6961 gccaatcagg gtcgtcacat aagaaacgta aggaagcagc ttccagccaa tgtaacccac
     7021 acctgttcca ataataattg gcaacaaaat aatggttaga gacccaaatt tatcaccaaa
     7081 ccacttcact gctaaaacgg caagcgcagc tgtgatcatc atattaatca gatcaccaat
     7141 gccctttagc tggaaggtcc cagtggcaac acctttttgg ataacctctg tataagccca
     7201 agctccagaa ccgatataag ctgccccgcc gacagccagc tgctgcattg ggttaaattt
     7261 gaactgctgt ccaatcaaaa aaccagccat aactggcgta aagaattgga aaacctggac
     7321 gatatgtaaa aattcagctg ctacagtatt tggcaaaagc ggctttaaaa acgtcgctaa
     7381 aatagcattc ggaataagtg caactacaat cgcaattgct gtaccagcta agaccttatt
     7441 cataaacgag ctaaaggtct ctttatttgt tgttgtcatt tcatgacctc tcttaatatt
     7501 atagtgtgaa aaacatcacg aaagtattct aacataaaaa gagcattttg tcacagctat
     7561 tttaattttt atcaatacgt acagaatatt caattaaatg tcatataata ttaatcaatc
     7621 aaggctgttg aatgaacagg tctattatct ctatcaggat aaatatactt aatcgcttgg
     7681 ttgacagcaa tcggtgcctc accaaagcca gtggcaatca aatcaaccct gccttcataa
     7741 gctgctgcgt caccgatcgc aaaaatccct tcctgacttg tttgaaagag gggagagaca
     7801 agaagacttg agcgcttata atctagattc caatgcttta ggtttttatt agatgtagaa
     7861 aagccaaagc taacaatcag gctgtctagc tcaagcgtta tctcctcttc tgactttacc
     7921 ttttgaatag tcattttgtt gacaaagcca ttttctcctt cgagggcaag gggaacaaag
     7981 ggggtaaggg tagtaacatg agagtttttt aacaattcta cgctatgctc atgagcccta
     8041 aaggcgtctc gccggtgcac aagggtaaca ctcttagcga ggccatctaa ggctaaagcc
     8101 cagtccacag cagaatctcc accaccgcag atcacaaccc tcttaccagc aaactgattc
     8161 aagctgtgaa cattataaaa gagattatga tcagcaaata actgctcatt gtctaagccc
     8221 aaggttctag gcgcaaaggc tccattgcca caagcaacaa taatggcctt agaataatgt
     8281 ctggccttgc ttgtttgaat aacaaagttc ccatcagcct tctcaaaaga caggacctct
     8341 tctttcaggc atactgctat gcgatcgtca aatctgctta gctgctcaat aagcttttgt
     8401 gttagttccg ctccagtcag ggccggataa gctggaatat catagataac cttttcagga
     8461 taaagaacag ccggctgtcc tcctagctct gacaggcttt caataatctt aaccgtcatg
     8521 ccgcgcaggc ctgcataaaa ggctgcaaat aagcctaccg gacctccacc aatgatggta
     8581 atgtcatata ttttttcttg cactagttct ctccttcact tagccccgat ttgattttat
     8641 caaaaatcct tttttcctca tcagaaaaat cataagtctc taataaatct ggtcttctca
     8701 aataggtctt ctttaggctt tgctccatac gccagagacg aatatgctca tgatggccac
     8761 tcattaggac atcaggcacc ttcatgccac gataatcata tggccttgta tactgtgggt
     8821 actccaagag cccagatgag aaggaatcct cttgatgact ggcttgcttt ccaagcacat
     8881 taggaatcag tctcactgtt gcatcaatca ttgtcatagc agccagctca ccaccagtta
     8941 agacaaaatc tcccagagat atttcatcgg taacaagtgt cttaatgcgt tcgtcatagc
     9001 cttcgtaatg cccacaaata aaaattaact cttcctcaag agctaattct tcagcataag
     9061 actgatgaaa gggttttcca gcaggatcca gtaaaatcac tcgaggcttt gtagcctgaa
     9121 tgctatccat ggtatcaaaa ataggctgcg ctctcagcag catgccctgc ccaccaccat
     9181 atggctcatc atcaacatgc ctagctttct ccgcatggtc acgaaaattg tggtaatgaa
     9241 tatctaaaag ccccttttcc ttagcctttc caacaatgga gtgctccaaa ggagcaaaca
     9301 tttccgggaa aagggttaaa atatcaatct tcatcatcta agccttccat aatttcaacg
     9361 tctacccgat gcttttcgat atcaacacaa agaacaaccg atgggatata aggaagcaac
     9421 aggtcacgct tgctttgccg tttgaccacc caaacatcat ttgcaccagg ctgtaaaatt
     9481 tccttaatct ctcctactag ctggtccttt tcatacacct ccagaccaat aatctggtga
     9541 tagtaaaatt ctccctcagc tagcttaccc tgattctctt tagcaatctt aagactgtag
     9601 cccttaaatt gctcaatagc attgatgtga tacattccct taaacttgat aatgtcaaac
     9661 tgcttatgct tgcgatgact cgcaatctca acctcctgca caaaacgatc cttgtcgtca
     9721 aacagggcta gtctagcacc tttttgaaat cgttcctcag taaagtcact cacagacagc
     9781 acgcgcattt ctccttgcaa gccttgagta ttgacaatct tcccaacgct aaaatattcc
     9841 atccttactc ctaatcatct tagactctat agcttgatag acctctattt tttcatgaca
     9901 acacgacatg agtatcatca tcctaagcac tctagcctat cgttaaagct ccccttattg
     9961 taacatgttc tgccttattt tgcacttctc tttcaaaaaa ttaatctccc agttatagca
    10021 gctaagccta gcaagcaaag cccttgatgc taaagaatcc tgatccccct ataattaaca
    10081 aatcatcatg acttgccttg cccaagctca gtcaagtgaa tgaaaaatct gctaaacaat
    10141 agccttgcgc ctcgctgaca agcatcaaaa aaacactcct gctggcaatc tgaactgccc
    10201 cccaattgtt agattttatg tccaactttt gggggtcagt acaatctagt aaactagaat
    10261 caggagtgtt tcattatagc ccaacaagca aaaggaatac ttggtaaaag caaagctgac
    10321 ttgcattgag aagattaaaa ccattcaatc tgtcacaata attatggaaa cattgggaat
    10381 ttaaaaacaa gtatcagctg ctatcaacct gtggggaaat agtctaccta tgcctatcgg
    10441 gccatccatc ataggtcctc tcaagaaatg atgagagcct catcaaccag ctatcatcgc
    10501 cttaaaggag aatgacgaat gttatcgtag gtgtcccaag aaatactaca aaagaaactc
    10561 attttgatct taatgctcta aagggcttga ccttacgtca actgataaag ctctacttca
    10621 tagcatcgtt ttgctttgca gcttttctat acctcatgtc taataaaaga cataagcttg
    10681 ccgataagaa cattacccca acatagaaga atagattggt ctcatcgcca gtctttagta
    10741 agatggtatt ttgatgcttc atcggtttgg tagctgttga aacatgcgga cacttggttt
    10801 catttgtcgt cgatggtatt gtcggacgac ttggcttagt gttattaggc ttatgattgc
    10861 cttcactact gcttaccttt ttcttccact gtgcaaacaa ttcattagga aacggcaggt
    10921 cattatctac cctaatgtca tcacctacct tttttaacct cctgctcgat ctcttgttgc
    10981 atacaaaatg ttatacagat acttctgtca gatagagttc ttgcttttgt ctcttgactt
    11041 ggtgattcaa aacacaaaaa aagcctgcta gatagaacta gcaaggcttt aagattagtc
    11101 ttgttcaaaa tagaacttat ttttcatcaa tgactaatcg aacctttttt cctaaagttg
    11161 gcaccgaata gacaatcgat cttatcgctg tgatggtacg acctttcttt ccgataacac
    11221 gaccgatgtc ttgagcatcc aagtcaagat ggtactctaa aaaatccgga gtatcttcaa
    11281 ttttaatagt aagcttatct ggttgtgaaa tcaagggctt cacaatagcg ataatgagat
    11341 tttcaatggt atccataggc ttttattact tagaaaattt ttgatcgtgg aatttagcca
    11401 taaccccagc tttagataga aggctacgaa ctgtatcaga aggttgtgca ccttttccta
    11461 gccaatcaag aacacgatct tctttaagag ttacttgatt ttcagctaca agtgggttgt
    11521 aggttccaac tgtttcgatg aaacgaccat cacgtggtgc acgtgaatct gcaacgttga
    11581 tacggtagaa aggttttttc ttagaaccca tacgagttaa acggattttt actgccattt
    11641 taatatgtct cttttcttta aatgataata gtcaagaaat gtagtcctgc tcatttctca
    11701 cctaactagt atactttact tttgattatg tgtcaagttt ttttcttgac acttttttat
    11761 gatcataata ctactcaaca tcttcaatca gctaagctgc ttagatgaca tcaaacagca
    11821 ggcagctgct cttataagag catacaactc caaactaacc tactctagtg atccttagcc
    11881 gtcaataatg ggatcaggca agcataactc cccgtcaaag gagcggtttg tttcacagca
    11941 aaaaggcgaa ataaactgac aatcacatca aaaaggacga gcccctaaac atgcaggagc
    12001 tcgtcctttt accaatatga cttagtctct ccttgctttt aaggctaggg tattagctaa
    12061 gcgttacact aataatgcat caaaatatgc ttaagaaact ctccaccata aatccaaaaa
    12121 taactgaagg tcaaaattga aatgggtcta caaattagga taatcagtaa aaagcgcttg
    12181 taggtcatct gactcaatcc agtaatcata ataagagcat cggcaggggc taagggggaa
    12241 atcatattga gaataaagaa acgctcaaat aatttcgttg atagcttctt ttcataaaac
    12301 tgtagctgct ccatacttaa aaacagtaag ataaagggct ttccgtatct cctcaccaac
    12361 tgaaacaaaa tagaagatcc aatgcagata ccaaacacat ttaacataaa gcctaatata
    12421 ggaccaaagg ctagaaagcc aacgactgtt gtcacaccac caggaatgat aggaacaact
    12481 acctgcacaa tttgcaagat aaaaaagcaa atggcaccga taaggagatg atccttgatt
    12541 aaatgggcta aagcctttgg attattaata atatctagct gcctaataag gtagacaaca
    12601 agcatgacgg agaacagaat tgataggcca ccaagaatct taaacagctt ctttaacaac
    12661 gaatgtgaaa caccaaagct actcatagcg caaagcctct atcggatcaa gcttgcttgc
    12721 tttgtttgct ggcagcaatc caaaaataat accaattgat gccgaaaaga taatagctac
    12781 agccgcaaca tctaaggaaa cagctgctcc ctttaattgc atcgcatttc ctagcacacc
    12841 tacacacatc tgtgctagca gcagccctaa aagaccgcca attaacgtca acaccactga
    12901 ttcaatcaaa aattggctaa gtatcttcaa gcgcgttgct cccaaggctt ttcgcaagcc
    12961 aatttcacgt gtacgctctg ttacagatac cagcatgatg ttcataacac caataccacc
    13021 cacaagaagg gaaattcctg caatggaccc aacaactgtg gtcatgatac taaattgtgc
    13081 gttaatgtca ttgataattt ggctattgtc aggaacagcg tactcgccct ccttaacatg
    13141 agacagtgtg gtcagcatag cagctgcttg atttcctaat tcaaggcttc gcttaacgtc
    13201 gccaatataa agataaacag agccaatttc cttgacatga aattctgaag ccacctgggt
    13261 attggccata atggctcctc cagaaatccc accagcaaac gaaacaacct cctgatcagt
    13321 cttgtaaaca cctactacaa ggtagtcctt actatctaga ctaaccacct tatttagagc
    13381 ttgttcataa ttgcctttgc caaataattc gtcagccaag acagtatcta ataggataat
    13441 gcgagaaaaa tttttataat ccttgctatt tagcgtccta cctgcaacaa tatcatattt
    13501 tttgacttta aaataatcct gactaacccc agtgatggcc acattgtcca tcttcttttt
    13561 ctcaaaggaa atggtagagg ttgaattatt ggtatagtaa taagaatcta ccccatcaat
    13621 tgctttgaca atctgctcta gccattcagg cttgacctct tgctcatttt catgcgctgc
    13681 aaaggccgcg taagggttgt cctcatctcc ttttgccttg aaataaagct gaacctcttt
    13741 ttggtcattt gaaaaggaat ccgtaaccct ctttgtcatg gcagcaccaa gccccatgat
    13801 aatcacaaca gcagctacac cgataataat tcccagcatg gtaagaatcg aacgcagctt
    13861 gtgcccccag attgaactaa gagcaaattt ccaattttcc atcacttttc ctcctagtca
    13921 atcctgacac tttctgttgt atcagctgtg atttcaccat cacgaataac aatttttcga
    13981 gtggcaaagt ccgcaatctc tggctcatga gtaaccataa taatagtttt gccttcctta
    14041 ttcagctccg tcaaaagcct cataatctgc tcaccagtct ttgtatctag ggcaccagtc
    14101 ggctcatcag ctaagataat agacgggtta ttaaccaagg ctcttgcaat ggcaaccctt
    14161 tgcttttgac cacctgataa ctctgatggc aaatgcttca ttcgcatacc aagctcaacc
    14221 ttttccaaaa attgcttagc caattcacga cgctttgata ctccaactcc agcataaatc
    14281 aagggaagct caacattttg cagggcattt agctttgcta gtaaaaagaa ctgctgaaag
    14341 acaaagccaa tctcttcgtt tctcacctga gcaagctttc gatcatttag gatctcaacc
    14401 tgtgtgccat tgagacgata atcacctgag gttggtctat ctaataagcc gatgatattc
    14461 atcagggttg atttccctga gccagaaggc cccataatag cgacaaattc accctcatat
    14521 acagtcaaat ccacgccttt taggacctgt agctcctgat caccattttg atagctttta
    14581 acaatgcttt ttaattgtat taattctttt ttctcatctg gcactactta atcacctcgg
    14641 attctttact gcttttttta gaatcttttg atgcctttgt gtctgcggaa ataacgtctt
    14701 ctagcttttc accctctttg atgttcttat cagggttagc aatgacaata tctcccacct
    14761 ttagacctgc acttacttct tgtctttcag catcagcatt gcctagggtt acttcaacct
    14821 ttttagcctt tgcagttgag tcatcataga cccagacaaa atgcttcttg cctttgttaa
    14881 cgatagcagt aactggtact aaggcatgct ttgcttcgtt gataacctca acagacaccg
    14941 taaagccttg ctttagctgg ttaagcggac tcgtgatatc aattttgtag tcataggtcg
    15001 caccagttga gcttgatgag cctgagcctc ctgcagttga accacctgca ttggcatcgg
    15061 ttgggtagtt tgacacataa gaaatctttc cggtccactc ttgatcagca tagacctttg
    15121 atttaatctt cacagcttgt ccaaccttaa tattggctaa atcatactct gttagggtcc
    15181 ctttgacctg taacttgcct tcggttgcga catgaaccaa ggtttgactg ttttttgaag
    15241 acgggtcaat atcattatta acctctacaa ctgtccctga aacaccactg acaactactg
    15301 tttcatttaa ggcctgctgt gctttattga cctctgcttg agcatcagca taggaatcat
    15361 ttaaatcctg caattgctga gcatagctag cattttgctg ggctgagggc tgaatggttg
    15421 tggtggtttc ttgccctgtc tcctcgtcct tgcttgtctc agtagttgct gctggaacac
    15481 catacgtttt taaatgatta atctgacgcc caattttatt gagattgcga acagcggtgt
    15541 cataagctgc ctgtggtaca gttgtattgt actgtactaa ctgctggcct tgtgtgacct
    15601 gatctcctac cttaaccgta acggtagcgt ctgagccttt gctagcatca aaataaacat
    15661 attcttctga aagagcttta acagtaccag agagtaaggt tgaagaggct attgtccctt
    15721 ctgttacatt taccgcagaa taaggtagct tgatattttg atcagagata gtatcttgct
    15781 gttgcttcca caatactcca ccgataacga ctacagttag tgcaactgca cctgcgataa
    15841 tgcctttggt tttcgttgat aactttatct ttcctctttt agacatttct gtcctcccct
    15901 tttgtactat ttttgtaaga caagtatatg atgtttttaa aaacttgtca agaatttctt
    15961 ggataagctt aataaagcag cctcttcatc atgtagatga caactctatt ataatggttt
    16021 ttcaagctgt actagcttac acttttgtaa tattaaaaag aggcaaagac aaaaagagtt
    16081 gtcctttaac tttattacac agtctcattc attaaaaagc gaacaagcct agttttcaaa
    16141 atctcagaaa actagacttg ttcgtttgtt tagacttttc tctcagtctc ttcatcaggt
    16201 ttaaatagct tctatactaa aggtacggct ttcaagaact ctcagcattg ctactgctgt
    16261 atccaatgct gtaaacagag gaactccttg ttcgattgct gagcttctga tcatctgccc
    16321 gtccttatca gtcactcgtt ttgttcctac ggtattaata atagcttgaa tctgcccttt
    16381 tctcagtaag gctgggatat catgagcatt gtcgccaatt tttccaacta gctgtgaatc
    16441 tagcccttgg tcagcaaaga aagcagctgt gccttcggtt gccatgatct ggtagccaat
    16501 agcactaaag cgtctagcta agatcagagc ctccgactta tggtcatcag cgatggtaaa
    16561 aactattgtt ccatattccg gcatgtgcag atagctagct tcaaaggctt tgtaaagggc
    16621 tttttcaagt gttaaatcag agcccatgac ttcaccagtt gatttcatct caggccctaa
    16681 aaggctatcc accttagcga gctttgcaaa tgaaaaaacc ggtgccttga tatgaacaag
    16741 cgagctttca ggataaaggc catcttgata acctaagtct tttaaggtct gacccagaat
    16801 aagcttcgta gcgacttgtg ccattggaat attggttact tttgataaaa atggcactgt
    16861 ccgactggca cgaggattga cctcaatgac atagacctgc tcattttgga tcacaaattg
    16921 gatattcatc atgccaatac agtttagccc tatagcaaga cgcttagtgt aatcaacaat
    16981 cttgtcttga acctgtttag ataggtgctg cggcgggtac acagccattg aatctcctga
    17041 atgcactcct gctctttcga tatgctccat gatccctggg attaagactg attgaccgtc
    17101 agagattgca tctacctcgc attccttacc aaggatataa gaatctatta aaacaggatg
    17161 ctcaggacta gccttgacag ctgttttcat gtaggagcgt aaatcgtttt cattttcaac
    17221 aatttccatt gctcggccac caagaacata agagggtctg accaataccg gaaagccaat
    17281 ggcacgcgct gcctctaagg cctctgcctc attggtggct gttttcccag gaggctgagg
    17341 gatccccagc tccttcaagg ctttttcaaa aagctcccta tcctcagcac aatctaagtc
    17401 ctctagctgt gtgcctaaaa taggaactcc ggccttggtt aactgctctg ctagattaat
    17461 agcagtttgt ccaccaaact gtaggattac tccctttggc tgctctaatt caataacgtt
    17521 catgacctct tcaaaggtta agggttcaaa ataaagcttg tctgatatcg aaaaatctgt
    17581 tgacactgtt tcaggatttg aattcatgat aatggcttca tagcccgcag cctgaatagc
    17641 cttgacagaa tgtacggttg cataatcaaa ctcaactccc tgaccgatgc ggataggacc
    17701 agagccaagg acgataacag attctttctc ggatttgatt gattcgtttt cccactcata
    17761 ggtcgagtaa aaataaggcg tttgtgagtc aaattcagct gcacaggtat caaccatctt
    17821 ataaactggc aagacacgat aggctcgcct taaccgtcta atacttgcag catcagtttg
    17881 ccaaagctct gcaatttttt ggtctgaaaa accatatcgc ttggcttcta tcagcaaatc
    17941 gatatcaact ggctttttaa taaggtcttg ctccagttct acgatatgac gtaatttatc
    18001 caaaaagaat aaatcaatct tggttaagcc agctagctct tcaatactat agccacgacg
    18061 aagggcctca gaaagataga atagacgatc gtcctgtgct cttacaatgt gagcaaccag
    18121 ctcatgatca ctgatagtat ctagaccctt cagttcgtta tggtgtactc caatttccaa
    18181 cgagcgacaa gcctttaaga gacattcctc aatacggcgt ccaatagcca taacctcacc
    18241 agttgctttc atctgggttc ctagacgacg ctccccccgc tcaaacttgt caaatggaaa
    18301 gcgtggcagc ttggcaacca cataatcaag agctggttca aacatggcat aggtggttcc
    18361 tgtgaccgga ttaagcatgt catcaagcct taagccaact gcaattttag cagctatttt
    18421 agcgattgga taaccagttg cctttgaagc cagtgctgat gagcgagata cccgcggatt
    18481 aacctcaatc acataatagc tgaagctatt gggatcaagt gccagctgaa cattacagcc
    18541 tccttcaatc ttaagggcac gaataattct caagctagca tcacgaagca gctgattctc
    18601 aacatctgat agggtttgtg tcggggcaaa aacgattgaa tctccagtat gtatccctac
    18661 tgggtcaaaa ttttccatac tgcaaacaac cagcgcgtta tcagcagcat cacgcatgac
    18721 ctcatattca atctctttaa agccggcaat ggagcgttca atcagacact gggtgacagg
    18781 agatagcttc aggccattct ccacaatatc tcgcaagacc tcttcattgg agcaaatacc
    18841 acctccagtg cctcccagag taaaggcggg gcggacaata acagggtagc caatggcatt
    18901 tgcaaagccg atagccgcct ctactgtcgt cacaatctct gattctggaa taggctctcc
    18961 caactctttc attaattgct taaataaatc acgatcctct gcctgatcaa tagcagataa
    19021 ggttgttcca agcagctcca ctcctaattc ttgtaaaata ccagccttag acagttccat
    19081 cgccatgtta agaccggtct gcccacctaa ggtcggcagc aaggcgtctg gtctttcctt
    19141 tcttaagata cgactaacaa atgccaacgt caggggctcg atataaacct tatctgcaac
    19201 ctctttgtct gtcataattg tcgcagggtt agaattaacc agaacaacct gatagccctc
    19261 ttcctttaag gctaaacaag cctgtgttcc tgcgtaatca aattcagctg cctgcccaat
    19321 aacaatagga ccagacccta tcaccatgat ttttttaata tctgtacgtt ttgccataat
    19381 atctggtaca aaaggcctta acaatccgaa taaaataatg caagcaccta acattaaagc
    19441 atcacaatct attttttact aggatttgta cctgtactca gctgcagcaa gccctttgta
    19501 cctactcctt tcattatttg ccgtctcaca gggcggcatt aaataaaaca cttaacagtc
    19561 tgtcacatga gacgatgagt acaagatcaa gtaaccctta gctcagcaag tatagatgac
    19621 ttaattgata tagtcttttt acttctaaag agggcgatct tgccagcaaa tactagtcat
    19681 aacccgcggc agagcgatca tttcccacta gtctatctgc tgcctgactc aagctgtttc
    19741 atgacagctg atcaagcctt tggtgcttgc tttttgatct gctagcacac ttgattaaca
    19801 tttgccttgc tgctctagct gccaggcgtc aatcatatct aaaaattcat caaatagata
    19861 gctagcgtca tgagggcctg gtgcagcgtc tgggtgaaac tgcacagaaa aggcgggaac
    19921 atgtcgatgt ctcacccctt caacagtttt gtcattaatc tcctcgtgcg taaccatcaa
    19981 gcagtctggc aagctgtcgc gctcaacagc ataaccatga ttttgactag taaaatcaat
    20041 acgtccggtc gctatttctc tgacagcatg attaaagcca cgatgtccaa aaggcatttt
    20101 aaaggtctta gcgccattag ctaagctaag cagctgatgg cccatacaaa tgccaaaaat
    20161 tggaattttt ccttgaacac cacgaatcat ctccaaggcc tccggcaaat cctctggatt
    20221 acctggacca tttgatagca ttagaccatc tgggttgagc tgtagaatct cttctgctgt
    20281 gatatcaaag gggactattg tcatctgaca ttgccttttg gataattctc ttaaaatgga
    20341 atgcttcaag ccaaagtcca ccaaaacaat atttttccca acacccggag cgggataggc
    20401 agtcttagtt gacacctgct caataccatt agtcggaagc acagttgcac gcagctgatc
    20461 ctttaggtgt tcaagcgtat caccatcatc tgccattgtt gccttcatcg taccatgctg
    20521 acgaatgatt ttggtcaacg ctctggtatc aattcctgaa atgcctggaa tccccttatg
    20581 ctttaaaaac tcgtccaagg tcatttgctg acgccaattg ctagctatcc tgcttacttc
    20641 agagacaatg acccctttgc aagttggggc aatggactca taatcatcac gattaatacc
    20701 ataattacca acaaggggat aggtaaatac taagagctgc ccgttatagg actggtctgt
    20761 gattgactcc tggtagcctg tcattcctgt attaaagaca atctcgccag tgacatcaat
    20821 atctgcacca aagggctttc cttcaaaaat ggtgccatcc tctaagataa gtaaccgttt
    20881 tgccatttta accccctcta acatgccttt agaccttatc gtttctgcca ttaaggatcg
    20941 cttcgataat ggccatacgg acaaatacac cattagccat ttgagctact attcttgcct
    21001 ttggagcctc tactaaatgg tcagcaatct caacatcgcg attaaccggt gccgggtgca
    21061 taataatcgc agagtccttt aaccgcctgt agcgctcctc agttagacca aactgtctat
    21121 gataatcttc cttggaaaag ctttgactac catcatggcg ctcatgctgc accctaagca
    21181 gcatcaacac atctaattga tcaataatgt gatcaatcgc catgtacctt ccatagctgt
    21241 caaattcaga cgagtaccat tgctcaggac catagaaata aagctctgct ccaagccgct
    21301 ttagaatctg catgtttgat ttagccacac gagaatgtgt caaatcccct gcaatagcaa
    21361 tcttcaggcc atcaaaatga ccaaattctt cataaatagt tagcaaatca agcaagcatt
    21421 gactagggtg ctgacctgat ccatcacctc cattaacgat agaggcagta atcgttggac
    21481 tgtcaataag ctgctgatag taatcatctt ctgggtgacg aatcacgcag atttctgttc
    21541 ctagagcact catggtaaga acagtatcat ataaggtttc ccctttattg acagcacttg
    21601 tatcagcgtt aaaatcaagg actctaagac caagcttgtt ctcagcaacc tcaaaggatt
    21661 tatgggttct tgttgaattt tcaaagaata aattagctgc aaagtgccta ctgttatctt
    21721 taatagctac cttacctgcc ttgtattcag agccacgact aataagtcct aaaacctctt
    21781 catttgttaa atgctccatt gacaccaaat gcttaagcgc aacacgatta tttacaactg
    21841 acatgattta tcccctttta ccaataatga aatgatgata acaattgaca acagctacac
    21901 actagttttc tggaagaagc tgatacaata taatgccaag aagcgttgaa aaagcaacac
    21961 ccgaaatctg aaggccattg atttgaagca tgaggcctcc aataccagaa accagaataa
    22021 cactagcaat caataggttt ttcttgttgt ccatatcaac cttagcttca atcaggattt
    22081 tcaagccact agaggctata accccaaaca gagcaatcga aatccctcca atcactggag
    22141 taggaataga ctgaataagt gctgatacct taccaacaaa gcttaacaaa ccagcaatca
    22201 cagcggcacc tgcaataaca tagactgaga agattttatt gagggccatc acaccaatat
    22261 tttcaccata agatgttacc ggaggcgctc ctaaaaatcc agcaatcacc tgtgcaaggc
    22321 catcacccgt caaggttttt tccaagccag gatccttgaa ataatctctt ttagtcaggc
    22381 tattaagcac catgatatga ccgaaatgct ctgtcatggt gacaaaggca atcggggcca
    22441 tcgttaaaat agcactagga tacaaggtaa tgtcataggt taaaaagggg atagccacag
    22501 ctggaacact gagccattgg gccttagcaa cctgtgtaaa gtcaacaata gactgacccg
    22561 tcaccatacc aacaaggatc gcaaacaaat agccaaccaa taagcccaac aaaataggaa
    22621 tgatggcgac aatcccttta ccataaatgt taaagaaaat aatcgctaat aaggtgacaa
    22681 gaccaatcaa aaggtataac aggttatact ttccatcctt tagcatgaca tcactaactg
    22741 ctgttgaggc caagctaaga ccgatcacca taacaatggg accaaccaca actggaggta
    22801 agatcttatc gatccattca ttgccaatcg ccttcaccac cagtgctaca accagataaa
    22861 ccaggccacc tgtaatcgct ccctgtgcaa ctgcaccaat accatctgtt ttcattagca
    22921 tttgcatggc tgcaatataa gcaaagcttg agcccatata agcgggaatt ttaaatgttg
    22981 ttactgacaa atgcgccaga gtcccaagtc cacttgataa gagggcaact gacggatcaa
    23041 tcccaaccaa aattggaacc aaaacagttg ctccaaacat agcaaataaa tgctggaagg
    23101 acaagccaag caaaatccct gcctttggca cttcttctac atcataaatg acatctttca
    23161 cacaatcacc tctttcttat cccggatcaa caatactaat acgatcttga ccgtcaacct
    23221 caaccacctc aacgacaatc tcttctgtct tgcttgtggg aatattcttt ccaacataat
    23281 cggcccgaat tggtaattca cgatggcctc gatccaccaa aacagctagg ctaacacgtc
    23341 caggacgccc taagctaacc aaattgtcga tagctgcccg aatcgttctg ccggtataaa
    23401 gcacgtcatc tactaagata atatccttgc cggtaatatc taccggcatg ctggtggtgt
    23461 cctcttccac tctcatatca tctctaaagg gcttggtatc tagctctcca actgccaagt
    23521 gcaggctttc tagctgctct aatctttctt gaatacgacg agcaaggtaa acacctcttg
    23581 ttttaatccc tacaagcacc acattgtcta gttgcttgtt gcgctcaata atctcgtacg
    23641 taatccgcgt gatcgcacgc ttcatggtta gctcatcaac aattaccttt gatttcattc
    23701 aaagcctcct caaaaaattc aactaaaaaa atctccctgt taacaaggag attcagcaaa
    23761 acaggcacac agctagacat aactgtgcac ttttttattc agaacatgct ccttgccagc
    23821 ctcacaggac tgttttaaag gaatatttta ttttcattag tatagcaaaa tcacaagcca
    23881 aaaacaagga ttttctaaaa aataattcaa aatatataga gctatcacag caccaaggaa
    23941 aatgctacta aggtcatcag caatcctcca acacaattcc aaaaataggt cttaagacct
    24001 attgtatttg tatcaaaaca atagtacaat aatatcaaac acaaaggaga gcgtttatga
    24061 tgaatgatat aactagaaag attaaccata agcaactgat tcaaatcact accattctag
    24121 gcattattgt taccatcgtt attttgttct atctgcagca gcaccctaat ctttttgcag
    24181 ttggcggtcc ttttcagacc tatcttatgg aacttggtat cctagcaccc tgtttgttta
    24241 tactgcttca aatcattcaa gtggtttacc ctatcattcc tggaggcttg acctgtgttt
    24301 tagggcatgt agtctttggg ccgttttggg gatttcttta taatactcta ggtattttta
    24361 ttggttcgct gcttagcttt atgctcgcta gaaaatatgg tgaacagttt gctaaagcct
    24421 ttgtatcaga tgatacctat aacaaataca ttccttacct caataaaggc aagtactttg
    24481 aacgatttct cataacagcc tttattctcc ctggctttcc agatgatttt ctctgtatgg
    24541 tagctggact aagcagcatg tctatcaaaa catttaccag tattttcttg atatcaaagc
    24601 caattactct ttatatctac acccttcttg cttaccaagg catacaaatc gttggacagg
    24661 tattgcaatc ctaaaaaaag ctagtattaa gctatcaagc ctgattggaa tacagtattc
    24721 caatcaaaaa ggcgctcagc ttggtaccag ctttttatcc ttgtcttagt tgctccaaag
    24781 tcctttggaa gatttctggt ggctcaacag taaagaccag ctcctctcct gtcacagggt
    24841 gggttagtcc caatgtttgc gcatgaagaa actgcccctt gccagccaag gtcttacgag
    24901 gaccgtagag tggatctcct gcaagagggt gaccaatata agccatatga acgcgaattt
    24961 gatgcgttcg acctgtttcc aattgtaatt ccacgaaggt atagtggcca aagcgctcca
    25021 aaaccttaaa aagagtcaag gcttccttgc ccttagcagt tacggtctgt tttttacgat
    25081 ccttttcact gcggccaatc ggagcttcaa ttacacctcg atcctttggt aaattaccat
    25141 gaacaatggc cacatacttt cgtaaggatt tcttagcctt gagctcatca gctagtagct
    25201 ggtgggcctt atcggtcttg gcaaccatta aaagaccaga ggtatcctta tcaattctat
    25261 gcacaattcc tggacgaata acaccattaa tagaagacag gtctttgata tgatagagca
    25321 aggcattgac cagcgtccct gtagaatgcc ccgcagaagg gtgaacaacc attccctgag
    25381 gcttattaat aatggccaat acatcatctt ggtagacaat atctagtggt atatcctgag
    25441 cctgatagtc caagctgctt tcctctggga tatgatagct aatgcagtca cccacctgca
    25501 caatatactt ggccttctta ggtaagccat tgaccaatac ccttttttgc ttgatctgat
    25561 cattagcctg acttcttgat aatggggtca aatcagccaa ggccttatcc aagcgatggc
    25621 ctgattctgt tatcttaatt tccatagtcc tcttctttcc atagacaaat gaccagcagc
    25681 aaaacaccta tcgtcaaata ggaatctgcc acattaaaaa tagcaaaatt gatcacatct
    25741 aaatgaatca tatcaaccac ataggataac ctcaagcggt caataaaatt cccaagacct
    25801 ccagatataa tcagcaataa agagagctgt agccaaaagc tagcctttgg gtgcttcaac
    25861 acataataaa tggcatagcc aaccaccaaa acagttatga ttgtaaagaa ccactgctga
    25921 ttctgtagta tggaaaaagc agctcctcga ttttgaagat aggtcaagct caccaaacct
    25981 ggtataaagg gcttcacctg ccctagctca atatgtgtaa cagtccacca tttacttagc
    26041 tgatccagta tcattaagac aatggcagcc ataataaaac taattctttt caactaatcc
    26101 tattcctttc agcttaaaaa caagagatta ccttgatggc ttcaaaaaag caacaacagc
    26161 cagctgtctc tgtagcgtac tcaaccttaa agcctccaaa aactggtatt ctagtaacct
    26221 tttagtatca ttgatagtca accacacagc agctctagac ttgactttat atcaacaagt
    26281 ctcaccacag cagctcgctt aatccttatc cataccagag ctaagtccca ttgtctatag
    26341 cttgcttttc ttttcgatgt tcaaaataat cctgtaaaat ggtcacaaaa tgtaaagccg
    26401 cagcagatag gttcttatcc ctacgcttga cataaatcat tttatgctcc atatgatcac
    26461 gcaagggaat aaccttgatg ccattaacgc tttgctgatc taaaaatcca gaccctgttg
    26521 caaaggcagc tgtcctttcc aaaatgccat ttaaggttgc cctatctgac acagtgtata
    26581 tgtgaggact cttgcttgtg tcaataaaat tttctgaata ataaagatat tcttcttttt
    26641 cttgagtaaa gcgtaccgct ggcagccctt gcaaatcctc taagaaaagg gctttccttt
    26701 gagccaatgg atggtttttt gataggtaaa tatgggttgt aaaggatagc aattcaacat
    26761 aatccaaagc cagcttatcc attcgctgaa aaagcccctg acggttttgt gcattaagat
    26821 agataattcc aagctcacta tttccctgtg ccacctcatc taaaatttgc atagtcgttg
    26881 actcaaaaac tctaaaaacc ttatgcccag catgcttttg ggaaaatgct gttattaaag
    26941 ctggtaaaaa atcataatgc tgactcgcaa ttgaaaattc atttggctcc aaagccgatt
    27001 gagaaaactc cttttccagc gagtcaaagc acttaacaac ctctaaggcc ttttcataaa
    27061 ataaaagccc ctggctggtt aacacagttc ctgctgttgt cctacgaaag atctgaaagc
    27121 caagctctgt ctccaaatcc ttcactgaaa cagacaaact gggttgactg acaaatagct
    27181 ttgaagcagc ctcacgaaag gtaccattat ttgcaatagc aaccacatat cgtaattgtt
    27241 gaatattcat taatccactt cctaaatcta gtacccttca ttataccata aagccagcca
    27301 atgaaaaata aaggcgtcca tcttaaccat gccaaacgta tctacagata atcatgagat
    27361 agcattgact ttttcaatag tgtcttatca tatttagcta tagaaaacag ccttactata
    27421 agttatactt ttgaaagaag taagccttag atcacagaac atcacactga gattttttat
    27481 gcgcttatcc tgtctgtcca agaactgaga attggctaca tctagctaat aagccatttc
    27541 aggattttac tgtctaggag ttatttatag gcaactatta cagtaagata gtgtcacaat
    27601 acaaaaaagg ctatcccaaa gtacagaaca gccttatacc gtgccctttt aacacattat
    27661 tttgcgattg ggtatacaga aacttgtttc ttatcgcgtc ccttacgctc aaagcgtaca
    27721 acaccttcaa ccttagcaaa aagagtatca tctccgccac gaccaacgtt aacaccagga
    27781 taaatatgtg tgccgcgttg acggtaaagg attgaacctc ctgaaactgt ttgtccatca
    27841 gctgccttag cgccaagacg ttttgcttgt gaatcacgtc cgttagaagt tgaacctcca
    27901 ccttttttgt gggcgaagtg ttgtaggtta gaaagattaa gtttaatcat ttttatttcc
    27961 tctcgttgaa tttaattcat cacaggcttt tgaacatatt ctgataaatg ctctgccaaa
    28021 ttctccaagc caatcacaac agactcaaac agaatttgcc acacctgctc ttgttgctca
    28081 gtaaatccct caggctttgt tacccttagg aatccaccac catcgaccat ttctagtgct
    28141 ggctcaagac ctgtcatctg ttcaactgaa ttaacaagat tgaaggccaa aactgaaacc
    28201 gaagcacaaa ctacatcaaa gccgtactca ccgcttccag catgtcctgt gataagcatc
    28261 tcagtccagc cagctgcgtc ttttgttaac cgtactttaa tcatgtcaaa ctagaattat
    28321 gccttgatag cgttaatcac aactttagtg taaggctgac gatgaccttg cttacggtgg
    28381 ctaccttttt taggcttgta cttaaaggtt acaaccttct tttgttttcc ttgcttttca
    28441 acagttccaa cgacagtagc tccctcaaca actggagtac caacgacagt cttatcacca
    28501 cctacgagaa caacctcgtt aaaagtgatt tctgcgccag cttcagcgtc aattttctca
    28561 acgtagattg cttgacctac ttcaacttta acctgttttc caccagtttt gatgattgca
    28621 tatgtgctca tgatgcacct cctataagat ttttgatgag gtttccctct gtgaagactc
    28681 gcctagaatc gtgagagcca atctacttga aaacgatttt cgtgcggttg cacaggacgt
    28741 gcacttagtc aacgttacaa ttttaacatc aaatttgatt tttatcaaga aaaatatgct
    28801 tttatcttcc taaaatctta agctatacat aatcacagct atgtaaaggc tagcaatgct
    28861 ttaccatttt aggttaacca gggcattcat ttctttataa gcaatagctg ctttttcttg
    28921 cgtttcggga tcaatcttat cataatatct gccgcctttg ataaagtcct ccaaaaccat
    28981 ggtacgatag ctatatagct catagccttc actaccataa aggcccttag gcttagctaa
    29041 aaccattgtc gggtgagcct ttactgtttt tatttttgtt ttttgcccct tcttctcaaa
    29101 ggtaaggtcc attagcacgc cgcgctctgt ccaaatatca tcaacagtct ctaggcgttg
    29161 attggaaatg aaattaccca ttgaatagat aataaatttc ttttccttgt ccttaacaat
    29221 cgtctctgcc ggctctacga cgtgggggtg acctcctaag acaacatcag caccccagtc
    29281 aatcattttt cgataaagag ttttttgctc agctgttggc tctaaagcat actctgtgcc
    29341 catctgcggc ataacaatgg taatatcggc ctctttttca gcacgcaaga tgtctttttg
    29401 tatcttttcc tcattaaggt cagacaggtg cttgtcatac tcctcctgac tgagtgtcgc
    29461 ctccattcca ttatagccat atgaatagcc caatattgca atcttaatcc cattaacctt
    29521 tttaatgaga atgttctcct tagagcgatc ctgctcataa ataccaatgc tgtctatccc
    29581 catatcagca aaaacacgct tggtattgag agctccttct aatcttgagt ccaaaatatg
    29641 gttatgggcc aaatcaacca catcatagcc agtatgctta agcgcagcag caatagcctc
    29701 tggcgcatta aacaaaggat agccagctag aggatagtct ggactgatcg ttccctcata
    29761 gtctccaatg gccaaatcag cctgactaat ccaatccttc acatactcaa aatagggatt
    29821 aaaatcatag ctaccatcag cctttttagc actcatatag agaatatcat gaatcaaaat
    29881 atcaccattt gcgacaacac gcgctgtttg tgtcttttga ggtgtcttgc ttttcgtttg
    29941 tgtgcctttt tttgacatgc ctaataaatc aaaggccaac ccaaaaacaa gtatcaccac
    30001 aatcaaggta agcactgaaa gcatggtctt tttatactga aaatctttta gcaagcgtca
    30061 aacctccttt tttcctatta taccatgttg acacgacttt ttaataacaa atcccaaaga
    30121 aaaggctatg cccatttaag aagaatgcct tagacagcag catagactcg tattagctag
    30181 tcaaaaaact agattgctcc tctttggttg atgtcatata ctttgagcct aaatagcttt
    30241 caacaaagtc taatagttga ataatgtcat gcaaaatatg gtataatgaa acaaaatcaa
    30301 actagtcagg atagtcacat gaagcataac tctttcagcc gctcactatt actccccctt
    30361 ctcatctgtt ccttgtctgc ttgctcttct catacagaga aaaaagacca taccaaagac
    30421 gctactgcta tcaccgatac ccgaaaagca gagcatcagg acatcagggc aaatatggaa
    30481 aaggtcaagc tcgctaccgc tagcaccgac ttcaaaggtg gctcaagcct tgaggagcta
    30541 atcactattt ttggacagcc tagtcagcac gaagaaaaag cagctggtag tgttactctt
    30601 gactcctaca catggcagtt tgaccatgtc acggttaata ttaacctcta tgaaaacagc
    30661 agcattgtta aaactattgc taactttgct tttattagag acctgacctt atccttaaag
    30721 gactacaaca gcttgaaaaa gggcatgacc tatgatgagg tcaagcagct attgactgag
    30781 cctgataatt acagtcaagc caattccagt gaaaaagaaa ccattcaagc catttggatt
    30841 agtggcttaa aagctcagac acagggtgcc aatatagcac taacctttga aaacaaccag
    30901 ttgacagaaa tgtcacaggt tggtcttgaa gactagtttg tggataaccc caatcatatt
    30961 aatgatagaa aaaagcttga tatttaataa gatcaagctc aaacgataga ccaagtagct
    31021 gatgatcttg acagtaatgt gtaacaagct gagatactac tcactaggca gtatttacta
    31081 gcagccactg aatttccttt atgatgacag gcaaccacct tttttgtggt gacctatcaa
    31141 tagcaccata agctctcttt tgtcacatac cttgcttaac attattttac caggtatgtg
    31201 atgagctttt taggttgtct gatagtataa catctaaccc ctagttgatg atgtagataa
    31261 ggcaagagct gctaaggata gcaccataaa taagatccaa catagggtca tattatatag
    31321 tgccaagaac gaaaagataa agacacctac agggagcgat aaagagaaca gaagacctaa
    31381 aaagttattg ctttgggcta gcatatctga tgggagattt tccattaaaa gggcgtccag
    31441 cttgggtgtg gcttttccca taatataagc tgcaaaggct aagcataaaa cccctatgat
    31501 ggcaggtaat tgcagagcat tagagactcc taccagcaaa aatgctatgc cctgagtctg
    31561 tactagcttt gatattgaaa gccttgaaaa gtaatccttt ggtgttagat ttcccaacat
    31621 cgctccgata atcgtaacgg catcaacaat aactaaagac tgcccataat gaaaatgaaa
    31681 tagctgatga tccatcaaat aaaaatgata aatgctatta attgctcctc caatagcgtt
    31741 taaggtcaag atggataaga gtaacatcac aaaagagata tgatcaatct ttttaaaggt
    31801 ctctgtcatc cttgtataca tcaccttaaa ttgcttcatt aatgaaacac ctgcttcaga
    31861 agcttcaacg acatcatgcc ttagcttttg tcgattttta agaagcacaa cagatgacaa
    31921 taaaaaggaa atagcattta tcaaagcaac aaaggcataa ttgttgcctg atgtcgttag
    31981 cagccaaact cctaaagctt gtcctgcaat actagagagg tagccgataa attgagcaaa
    32041 agaataggcc tcatagagct tttctgattc aatatttttc tgcattatcg ggagacgtaa
    32101 gccatttttg taatcactta gaatatcaga aaccacattc aaaaagccca caaaggcaaa
    32161 taccaagaac gtctgatttg tcatcaacaa ggctacaagc gtaaataaaa gagattgtat
    32221 aaaaccaata acaataagat ttcttgtttt cctttttgtc ttatctgctt tgacgccaat
    32281 ccaaaaggta aacaccatag gaatgatggt gatgatattg gctataaaaa cagcaatatg
    32341 agaataaggt agcgtggttg cataaataat aaaaacaata ttgtaaatat aagagcctaa
    32401 agcacttaaa aagtttgaaa ctgtcagtgt tctaaaaacg acatttttaa tcaatcccct
    32461 catttactta cctgttgacg tcctttctta tgtcacctta ctttacttga ttgaatatac
    32521 ttacagcata tctaaattcg tactgtagtt ttatatggtg ttctgacatg attttgctac
    32581 taattagtaa ttcacaagcc ttttctaagt ataaagtatc gtttgttagt ctaaatactt
    32641 gtaaaagtgt catggctatc cccagcattc cgttccatag accactaaac tgagcaaatt
    32701 caactaataa cgactccgat aaattcttaa tatctttaat atatttatcg gagttaacgt
    32761 aaataagcaa ttgaacgatc ccagcagtcc catttgataa gtatggagat acagaatttt
    32821 ctgatattaa tacaccccga tttccatcgc tatcttcaac taagctttct agaataaaat
    32881 caattccttt ctcaataatt tcgttatcat aagaaattga agacagatag aacaatactc
    32941 cagctaaacc atttaaccct aaattaactt ctgattttaa ttgcatcaaa acttcatcgg
    33001 atttatccaa aatcttatta tatttagtaa ttagtgtgtc ttgtaaagaa ataatattaa
    33061 caagttcttg attccaatca tcagatattg caatattagt atttaattta taagtacatt
    33121 gaaaatgata agaatagatg tcgttcctga tcatattaat agcctcttcg atgtctgaat
    33181 tctcactcaa aagatactca ataagcttat aaatattaga atttatgccc
//
LOCUS       DARYLJ010000023        32061 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYLJ010000023 DARYLJ010000000
VERSION     DARYLJ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32061
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TU746_000973"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TU746_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL0891330.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TU746_000974"
     CDS             complement(1584..2021)
                     /locus_tag="TU746_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL0891331.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TU746_000975"
     CDS             complement(2008..3234)
                     /locus_tag="TU746_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0891332.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TU746_000976"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TU746_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL0891333.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TU746_000977"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TU746_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL0891334.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TU746_000978"
     CDS             complement(5505..6662)
                     /locus_tag="TU746_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL0891335.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TU746_000979"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TU746_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL0891336.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TU746_000980"
     CDS             complement(7553..8392)
                     /locus_tag="TU746_000980"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL0891337.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TU746_000981"
     CDS             8708..10276
                     /locus_tag="TU746_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL0891338.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TU746_000982"
     CDS             10269..11009
                     /locus_tag="TU746_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0891339.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TU746_000983"
     CDS             11357..11473
                     /locus_tag="TU746_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL0891340.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TU746_000984"
     CDS             complement(11997..12887)
                     /locus_tag="TU746_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL0891341.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TU746_000985"
     CDS             complement(13150..14814)
                     /locus_tag="TU746_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL0891342.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TU746_000986"
     CDS             complement(14814..15179)
                     /locus_tag="TU746_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0891343.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TU746_000987"
     CDS             complement(15331..15519)
                     /locus_tag="TU746_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL0891344.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TU746_000988"
     CDS             complement(15979..16344)
                     /locus_tag="TU746_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891345.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TU746_000989"
     CDS             complement(16934..17815)
                     /locus_tag="TU746_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL0891346.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TU746_000990"
     tRNA            complement(18018..18103)
                     /locus_tag="TU746_000990"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TU746_000991"
     CDS             complement(18158..19084)
                     /locus_tag="TU746_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0891347.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TU746_000992"
     CDS             complement(19444..21057)
                     /locus_tag="TU746_000992"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL0891348.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TU746_000993"
     CDS             complement(21331..21897)
                     /locus_tag="TU746_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL0891349.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TU746_000994"
     CDS             complement(22164..23447)
                     /locus_tag="TU746_000994"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL0891350.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TU746_000995"
     CDS             complement(23796..25205)
                     /locus_tag="TU746_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL0891351.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            25656..26495
                     /locus_tag="TU746_000996"
     CDS             25656..26495
                     /locus_tag="TU746_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL0891352.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(26591..27151)
                     /locus_tag="TU746_000997"
     CDS             complement(26591..27151)
                     /locus_tag="TU746_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL0891353.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(27164..27637)
                     /locus_tag="TU746_000998"
     CDS             complement(27164..27637)
                     /locus_tag="TU746_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0891354.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(27643..28392)
                     /locus_tag="TU746_000999"
     CDS             complement(27643..28392)
                     /locus_tag="TU746_000999"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL0891355.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TU746_001000"
     CDS             complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TU746_001000"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL0891356.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            29318..30682
                     /locus_tag="TU746_001001"
     CDS             29318..30682
                     /locus_tag="TU746_001001"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL0891357.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
     gene            complement(31160..31645)
                     /locus_tag="TU746_001002"
     CDS             complement(31160..31645)
                     /locus_tag="TU746_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL0891358.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(31734..31807)
                     /locus_tag="TU746_001003"
     tRNA            complement(31734..31807)
                     /locus_tag="TU746_001003"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31771..31773),aa:Arg,seq:acg)
BASE COUNT         9542 a         7719 c         5807 g         8993 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat gctgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttgatgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat ttttttaatt tttatttcct
    25381 ttgctaaagc ctctaaaacc aatcaaaata atgttgcata agtatttgcc ttttatttat
    25441 ctcataatca gactcattcg ctctaatctt ttgcacatgt taatgtcatt tatttgcaga
    25501 cctacgcaac caattgcaca gagctttgtt tccttcgtca gaaaaacctc aataaaacat
    25561 aaacaagaag ccattactct tcttgataat gtttggtgat ctattttcaa ccaggacttt
    25621 ttttggtaaa ctagctacga tagaaaggag ttgccatgac gtttatatta acatacttta
    25681 atcagctaca cctagaaaat atcatggtgc ttgtgttttc taaattagtg tcaatcacct
    25741 tattattgat tttctttgtg atcttcaaaa aaatcacgac agctttattt gaaaaggcaa
    25801 tcgccaagtc attttcctat tcaagacaaa ctgaagcaag gaaaaaaacc ttatccaagc
    25861 tccttcacaa caccctaaat tatgttttct attttcttct catctattgg attttgagcc
    25921 tacttggtat tccagtatct agtcttttag caggagcagg aattgctggt gttgctattg
    25981 ggcttggggc tcaaggcttc ttgtctgatg tggtcaatgg cttttttatt ctgtttgaaa
    26041 atcaatttga agtaggagac accgtcacca ttgcaggcat tgaaggaacc atctccagcg
    26101 ttggtattcg aaccactcag gtgcgaggct ttgatggcac actacatttt attcccaacc
    26161 gcaatattac agttgttagc aacaaatcac gcggcaatat gagagctttg atcgatattc
    26221 cactttattc ctcaaccgat ctagagcatg tgacccaaat catcaaggct gtcaataagc
    26281 gagaggtgcc aaatttccca caaattgtcg gacagcccaa cattctagga ccacaaacca
    26341 atcccaacgg acaattcacc tttcgcgtta gcatttttac tgaaaatggg cagcaattta
    26401 cgatttacta tagcttttat aagctctatc aagaggcctt actaagggag ggtatcaagc
    26461 taccaactgc atctgccata tcacccttag cctagcagta aaaaccattg ctttcttagc
    26521 atacaaaagc cctatcccgc agccaggtca tcagacttag actgctagat agggctattt
    26581 cttttggctc ttatttccga ataggatcag gctgatacct ggctcttaca ccaccaatta
    26641 atttgggccg acttgctaag gcagtcacat gagcaccacc aagctctcgc tgaataggca
    26701 caagcggcac ctgtacacgc ttaacatgca taccaattga ggtatctcca atgtcaaggc
    26761 ctgcatgagc agcaatggct tcaacctcaa ctggctgctt catgtatttg aaggctgcta
    26821 attgaccact tcctccagca tgcaagctag gcagcacatt gactatttct agccgatatt
    26881 cttcagcaac actttcttct aataccaagg cacgattaat gtgctcacac ccctgaaccg
    26941 ctaaatgaat ccctctgaac gacaattcct ccaatataag cttcacaata acctcgccca
    27001 cctctaagct agaatgctgg ccaatacgac caccaagtac ctcgctagag gacagcccta
    27061 agacaaacag ttgccctttt ttgatagcac tacgctccac aatatcaagc aagatagagc
    27121 gtgcttcttc tctcaatact tttaaattca ttgaatcacc tgcttaatca tctgacactt
    27181 tgaccagctg ttttttgacc cctaaataca gcagatagcc tacacctatg ccaagggtat
    27241 tttgagcagc attccccgaa atttctgaaa tagcagcgcc cataccatac attggaatag
    27301 ctgcaagaaa atacagacca accattatca cagaagcaag gcccacgcca agaaagcgat
    27361 gcctgccagg caagcctgct aagtagccct gagccccatg agcaacaaga ctaatcagca
    27421 tccaattcgg gtaacctgag atcaaatcaa gcaaaaaagc tgataagccc ccaacaagca
    27481 taccctcctt tttcccaaga gaaaaggcag tcacatacac ccctgcatct aaaagactta
    27541 aaaaacctgt cggcgtggca atactcacaa acctgcccag gacaactgtc agggcagtca
    27601 agatagacac aagagctagc tctcttgtct gtttcatatt tatcataaga caactccata
    27661 atcatttgac tgttgaatgg cttcaaaaac aaggtcttta gcctgctcaa cagccctaag
    27721 cggtgaatat cccttagcta aataagcagc aattgcagct gcaaagctac agccagcccc
    27781 actgttttgt ttggccaaga ctggcttttc taaaaagcac agggtttttg cgtcataaaa
    27841 tagatctagg gcaactcgtt gatcaaaacg attcccaccc ttgatcacaa ccctcttagc
    27901 ccccatctca taaagctttt ttgccgcttc taccatttgc tccctgctat taatagcaag
    27961 ccctgccaag cgttctgctt ctcttaggtt gggagtaatc actgctgtta agggaaaaag
    28021 agagcgcaaa gcctgtgtca tttccacaac tgtctgatct tgattttcct taaatactaa
    28081 aacaggatct aaaacaacag ggatatcctt ttttagctct aaaaacaggg ccacctgctc
    28141 tgctatttca ggtcttggca aaagaccaac tttgattgcc tgaaaaggaa tagctgctaa
    28201 gctagacaac tgctttgcca gcaaatcagt cgcaacaggg tgaatgctga aacctttagc
    28261 atcacagctt gttaagcagg tgatagctaa aaatgcaaag ctatcgagct gatgaagcac
    28321 tgccaaatca gcctgcaaac caccaccgct gaatatatca ctcccagcaa tcgttaatac
    28381 cttattcttc ataaatgatt tccttcaaat aaagaccatt accagccgct gtcggtccag
    28441 ctagctgccg attcttactc tctaaaacga gcctgatttg ttcaatgggc aaccgaccat
    28501 tgccgatctt aagcaaggtc ccaaccatat ttctaacctg cttataaaga aagccattcc
    28561 ctgaaaacgt aaaaacaaga aaaccagttt tagggtcctg agtgagggta gctgctgtaa
    28621 tggtacgaac cttattttta acagaggttc ccgcagctgt aaagcctgta aaatcatgcg
    28681 tcccaaccaa atccttaatc gcagcctgca ttttcgcaat atctaaggga taagggtaat
    28741 gggtcgcata atggcgcatc ataggatttt taggacgacc aatatccact aagaattcat
    28801 aggttttgaa atgcttatgg tagcgagcgt gaaaatcatc tgctgcaatc tccagactga
    28861 tcacatcaat atcatctggt gtctgggtat caagtgcaaa gcgaagcttt tcagggtctc
    28921 ttttttgctc caaatcaaag tgaatcactt gaccataagc atgcacacct gcatctgttc
    28981 taccagctcc atgaatctgt atcccttgac cacctgtcaa tttttgcagg gtcttttcaa
    29041 tctcttcttg taccgtacgt gcctgacttt gtctctgaaa accagaaaat aaggtcccat
    29101 cgtaggaaat aattgcttta tatcttgtca tgctattatt ctaccatttc ttccagccat
    29161 cagaaaagag catttacggc ttttgtcccc atacagtttt cgattagctt tgataatcaa
    29221 gcttgatttg acgccaacag gcaaaaaaag gctactgaca aggactagct tttctgctat
    29281 aatttctcta atattcaata agtagactgg agagcaaatg aaggtaacaa aatttggcgg
    29341 cagctcctta gcatctgccc agcagttaga aaaggtcttg gctattatca aggacgatcc
    29401 tgagcgtaaa atcatcgttg tctccgcacc aggcaaacga tcccctacag acacaaaggt
    29461 gactgatgca ctcattgctt attacaaagc ctacgtctca gaccgtcatt atcacaagca
    29521 tttggaatgg attatcaatc gttaccaaca aatctgtaat gacctaactc tagatagcaa
    29581 aatcatcacc caaattaaag cttccttaga gcaattggca cggcttccaa aagaacataa
    29641 tccctattta tacgatacct ttcttgcggc cggtgaggac aataatgcta agctagtagc
    29701 tgcctacctc aaggcaaatg gcttaactgc aagctatctc caccccaaag atgcaggtct
    29761 aatcgtaagc agtgagccac agcatgcacg tcttcttcca atcagttacg ataagctaga
    29821 ggccttaaag gatcatgatg acattcttgt tattcctgga ttctttggtg tgacaaatga
    29881 aaaccagatt tgtaccttct cacgtggtgg ctctgatatt accggctcca ttattgcagc
    29941 aggagtcaca gctgacagct atgaaaattt tacagatgtc aatggcatct ttgctgccca
    30001 ccctggtgtt gttaagcagc cacagacgat cactgaatta acctacagag aaatgcgcga
    30061 gttagcctat gctggctttt ctgtcctcca tgatgaagca ttaatccctg cttaccgagg
    30121 gaaaatccca atcgtcatca aaaacactaa caatcccagc cacccaggta caacaattgt
    30181 tcttgagcac cagaggaaat ccaatcccgt tgtcggtata tcaggtgatg atcactttgt
    30241 cagcattaac ctatctaaat acctcatgaa cagagaaatt ggatttgggc gcaagctcct
    30301 tcagatatta gaggacctca atatcagatg ggagcacatg cctacaggta ttgatgacct
    30361 atcaattgta cttagagaaa gagaattgac ccccatcaaa gaagaagaaa tccttcgcag
    30421 acttgtccag caattagagg ttgatgaggt gtccatcacc aggaaccttt ctattatcat
    30481 gatagtcggt gaaaacatga aaagtcatat tggtgtcaca tctgccgcaa caaaggctct
    30541 atctgaacat catatcaata ttgctatgat ttcccaaggc tcaagtgagg tatctgtcat
    30601 gtttgtcatc aatagcaccg atgaaaaaaa ggccattaga gccttatatc aaaccttttt
    30661 tagccctgat cgacccctgt aaagctccat ataacatctc ttgttaacac caagcttcaa
    30721 aaacagctca caagctagac agtactccta gcctatgagc tgttttgatg atctaaaact
    30781 atcaagatta agcatcggta gtaacgactt aatatgctca cagctatcat aaactctagc
    30841 tttaccttat tgaggaaaag aaaaccagtt ttcacctcag ctaagattaa caacaagcga
    30901 ttaagcactt gctaaaaaca gatagacttc aaaagtgaga catatgtata atttctacca
    30961 gatctaaata aatatagcag cagagcaccg agtttaataa gccatttctg acatgataaa
    31021 ctcgccaagc tctccacaga tcaagatttg ccttatcaat tgatacaaca gccagcattc
    31081 tcaaagatgc acaagatcca tcacagtcta gccatctccc tgcacagtaa gcctttcaat
    31141 ctcgttccgg taaccccttt tatttctcac cagtaaagtc ctgaaagtaa ggtcctatct
    31201 tgcgaagcaa ggcccgtctc ccctcaaacc gctctcccct gatcaaagcc cgaaactgcg
    31261 acagctcacc ctctgtcaat cgctcctcaa cctccttcac aatcaactga taagccacat
    31321 aatcatctac tcccaaacca cctgctggta tcgcatggcc taccgaccca atctcctcat
    31381 aagccatctt atgaaaccga cgcttctgac tctcctgctg ccgcaacacg tccttcaaat
    31441 aagaggaaaa cttggtctta aaataacgat atagcttctc ctcatcctct atcaattctg
    31501 gataagtgac caataaccga tacaagatca accgcccctc ctgtaaccaa tcatctagct
    31561 cccacagctg aatataataa tgctgtctta gcttcataat aataggcttg atcttatcaa
    31621 acaacctcac taaatcatca gtcattatac tttctccttt tcatgcttag tagccttatt
    31681 ataaggagac aaacaaaaaa acaacaggac agaaatgtcc tgttgccttg ctatgcaccc
    31741 tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg tactctatcc agttgagcta
    31801 agggtgcttt tcttaactat tactatccta ccatactatc ccctaaaaag caaggctcta
    31861 taccatctgg aataggtaag tccactgtgg aaatcataga gctttttgag tacacaaaaa
    31921 agagagcacc aaactgatcc tctctaaatg tccgttgtta gtcaacccac tatagttgac
    31981 atagagccaa actccgccag taggactcga acctacgaca tcatgattaa cagtcatgcg
    32041 ctactaccaa ctgagctatg g
//
LOCUS       DARYLJ010000024        31752 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYLJ010000024 DARYLJ010000000
VERSION     DARYLJ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31752
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..1435)
                     /locus_tag="TU746_001004"
     CDS             complement(<1..1435)
                     /locus_tag="TU746_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL0891359.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TU746_001005"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TU746_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL0891360.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TU746_001006"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TU746_001006"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL0891361.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TU746_001007"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TU746_001007"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL0891362.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TU746_001008"
     CDS             complement(5344..6630)
                     /locus_tag="TU746_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL0891363.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TU746_001009"
     CDS             complement(6772..7143)
                     /locus_tag="TU746_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL0891364.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TU746_001010"
     CDS             complement(7130..7402)
                     /locus_tag="TU746_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL0891365.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TU746_001011"
     CDS             complement(7433..8944)
                     /locus_tag="TU746_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL0891366.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TU746_001012"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TU746_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL0891367.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TU746_001013"
     CDS             complement(12410..12979)
                     /locus_tag="TU746_001013"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL0891368.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TU746_001014"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TU746_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL0891369.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TU746_001015"
     CDS             complement(14337..14702)
                     /locus_tag="TU746_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0891370.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TU746_001016"
     CDS             complement(14823..15020)
                     /locus_tag="TU746_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL0891371.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TU746_001017"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TU746_001017"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL0891372.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TU746_001018"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TU746_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL0891373.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TU746_001019"
     CDS             complement(17976..18749)
                     /locus_tag="TU746_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL0891374.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TU746_001020"
     CDS             complement(18869..20092)
                     /locus_tag="TU746_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL0891375.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TU746_001021"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TU746_001021"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL0891376.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TU746_001022"
     tRNA            complement(21081..21154)
                     /locus_tag="TU746_001022"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TU746_001023"
     tRNA            21435..21506
                     /locus_tag="TU746_001023"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TU746_001024"
     tRNA            21539..21612
                     /locus_tag="TU746_001024"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TU746_001025"
     CDS             complement(21873..24458)
                     /locus_tag="TU746_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL0891377.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TU746_001026"
     CDS             complement(24581..26200)
                     /locus_tag="TU746_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0891378.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TU746_001027"
     CDS             complement(26280..27152)
                     /locus_tag="TU746_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0891379.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TU746_001028"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TU746_001028"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL0891380.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TU746_001029"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TU746_001029"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL0891381.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
     gene            30654..31046
                     /locus_tag="TU746_001030"
     CDS             30654..31046
                     /locus_tag="TU746_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0891382.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            31121..31522
                     /locus_tag="TU746_001031"
     CDS             31121..31522
                     /locus_tag="TU746_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0891383.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            31519..>31752
                     /locus_tag="TU746_001032"
     CDS             31519..>31752
                     /locus_tag="TU746_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0891384.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDST"
BASE COUNT         9884 a         6364 c         5841 g         9663 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa atagacatga aatattgtga aatatagaaa
    30541 tcatgttaaa ataatattat taaatagtta aattaaaaag aaatatacca aaatgattcc
    30601 atttattttt gggaatttat cgataagtat aggaatgata taggagtata gacatgaata
    30661 ggtttttaaa gatcagtctg cttattgttg gtgttattgt cattatgctt ggcatggaag
    30721 taaagcatag aatggatata tacgatcaaa tcaagcagga ggagataaaa attgcccaaa
    30781 gtaaagaagc aattgtgatt tatgaacagg agttaaaatg gttggaccca aatgcattga
    30841 caaatgaagg gactattaaa tcctattcta ttgatttaga ctcaataact cttaatccaa
    30901 tgggaggctt ttccattgct ttacatataa acaaaaatcc aaagtataag tatcgaataa
    30961 gtttaatgtg gaatacacca atgagagatt tatgtgtggg aggatcctct ttgtcgccag
    31021 aattacaaga attgttagat aggtaatgat tatgacaggc tatcagaaac aattgattgc
    31081 accaaagaac aatataattt tcatgaaaag gagcatagtt atgaaaacat tgttaaaact
    31141 cattgtattt attgttggta ctcttgtact tatgcttggc atggaggtaa agcatagaat
    31201 ggatacatac gatcaaatca aacaggtaga gctcaaaaac gcgcatagta aagaagtgat
    31261 tgaaatgtat gaacaggagc taatatcaat ggatccccag gccctaacag atgaaggact
    31321 tatcaagtcc tacactatcg actcagattc actctttatt aatccgatgg gaggcttttc
    31381 cattcattta attatcaatg atgatccaga tatttacttg agagttggcc ttggtagata
    31441 tgatatggaa agaaatttgg agattgatgg tatctatcgc tcagaaaagt tagaaaaact
    31501 actaaaagga gtggagagat gaaaacattg ttaaaactta ttgtatttat tgttggtgcc
    31561 cttgtactta ttcttggcat ggaggtaaag catagaatgg atatatacga tcaagtcaaa
    31621 caggtagaac tcaaaaacgc gcatagtaaa gaagcgatag acatttatga aaagaagtta
    31681 aaaagattgg atcctcaggc cctaacagat gaagggctta tcaagtctta tactattgac
    31741 tcagactcaa ct
//
LOCUS       DARYLJ010000025        31497 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYLJ010000025 DARYLJ010000000
VERSION     DARYLJ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31497
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..279
                     /locus_tag="TU746_001033"
     CDS             <1..279
                     /locus_tag="TU746_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0891385.1"
                     /translation="PKPGPKPEPKPEPKPGPKPGPKPEPKPEPKPEPKPEAKKPEQPK
                     PMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIAAGTIAIPKRKEED"
     gene            complement(525..839)
                     /gene="trxA"
                     /locus_tag="TU746_001034"
     CDS             complement(525..839)
                     /gene="trxA"
                     /locus_tag="TU746_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL0891386.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            1019..2338
                     /locus_tag="TU746_001035"
     CDS             1019..2338
                     /locus_tag="TU746_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL0891387.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2678..5014)
                     /locus_tag="TU746_001036"
     CDS             complement(2678..5014)
                     /locus_tag="TU746_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL0891388.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(5087..5632)
                     /locus_tag="TU746_001037"
     CDS             complement(5087..5632)
                     /locus_tag="TU746_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL0891389.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5632..5943)
                     /locus_tag="TU746_001038"
     CDS             complement(5632..5943)
                     /locus_tag="TU746_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891390.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            6061..6969
                     /locus_tag="TU746_001039"
     CDS             6061..6969
                     /locus_tag="TU746_001039"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL0891391.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            6994..7593
                     /gene="lepB"
                     /locus_tag="TU746_001040"
     CDS             6994..7593
                     /gene="lepB"
                     /locus_tag="TU746_001040"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL0891392.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7822..10221
                     /locus_tag="TU746_001041"
     CDS             7822..10221
                     /locus_tag="TU746_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL0891393.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10317..10802
                     /locus_tag="TU746_001042"
     CDS             10317..10802
                     /locus_tag="TU746_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891394.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10945..12048)
                     /gene="dinB"
                     /locus_tag="TU746_001043"
     CDS             complement(10945..12048)
                     /gene="dinB"
                     /locus_tag="TU746_001043"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL0891395.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12257..14581
                     /gene="pflB"
                     /locus_tag="TU746_001044"
     CDS             12257..14581
                     /gene="pflB"
                     /locus_tag="TU746_001044"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL0891396.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14887..15165
                     /locus_tag="TU746_001045"
     CDS             14887..15165
                     /locus_tag="TU746_001045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891397.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15329..16270)
                     /locus_tag="TU746_001046"
     CDS             complement(15329..16270)
                     /locus_tag="TU746_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL0891398.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16267..17022)
                     /locus_tag="TU746_001047"
     CDS             complement(16267..17022)
                     /locus_tag="TU746_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL0891399.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17515..18363)
                     /locus_tag="TU746_001048"
     CDS             complement(17515..18363)
                     /locus_tag="TU746_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL0891400.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKSSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18465..18917)
                     /locus_tag="TU746_001049"
     CDS             complement(18465..18917)
                     /locus_tag="TU746_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL0891401.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18937..20136)
                     /locus_tag="TU746_001050"
     CDS             complement(18937..20136)
                     /locus_tag="TU746_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0891402.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20305..20964
                     /locus_tag="TU746_001051"
     CDS             20305..20964
                     /locus_tag="TU746_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL0891403.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            20985..23270
                     /locus_tag="TU746_001052"
     CDS             20985..23270
                     /locus_tag="TU746_001052"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL0891404.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23376..23768)
                     /locus_tag="TU746_001053"
     CDS             complement(23376..23768)
                     /locus_tag="TU746_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL0891405.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23922..24179)
                     /locus_tag="TU746_001054"
     CDS             complement(23922..24179)
                     /locus_tag="TU746_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0891406.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24358..24732
                     /locus_tag="TU746_001055"
                     /pseudo
     CDS             24358..24732
                     /locus_tag="TU746_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24990..25772)
                     /locus_tag="TU746_001056"
                     /pseudo
     CDS             complement(24990..25772)
                     /locus_tag="TU746_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26289..27797)
                     /locus_tag="TU746_001057"
     CDS             complement(26289..27797)
                     /locus_tag="TU746_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0891407.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            28048..28944
                     /locus_tag="TU746_001058"
     CDS             28048..28944
                     /locus_tag="TU746_001058"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0891408.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28941..29204
                     /locus_tag="TU746_001059"
     CDS             28941..29204
                     /locus_tag="TU746_001059"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL0891409.1"
                     /translation="MKGEAGAPDTPQKPNDPLQSLEGGNSPIVEQNYGSTEGYHGQSG
                     ILEETEDTNPPGIILGGSGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29131..29937
                     /locus_tag="TU746_001060"
     CDS             29131..29937
                     /locus_tag="TU746_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL0891410.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30309..31355)
                     /locus_tag="TU746_001061"
     CDS             complement(30309..31355)
                     /locus_tag="TU746_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL0891411.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31357..>31497)
                     /locus_tag="TU746_001062"
     CDS             complement(31357..>31497)
                     /locus_tag="TU746_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL0891412.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9412 a         7418 c         6283 g         8384 t
ORIGIN      
        1 cctaagccag ggcctaagcc agagcctaag ccagagccta agccagggcc taagccaggg
       61 cctaagccag agcctaagcc agagcctaag ccagagccta agcctgaagc taagaagcct
      121 gaacaaccta aaccaatgac taaaccagga gctaagaagc ctgagcaatc acttccatca
      181 actggtgaca tcagaaatcc attcttcacg cctgcagcta ttgctattat gatcgcagca
      241 ggtaccattg ccattccaaa acgcaaggaa gaagattaaa caaattaaca atccccatat
      301 ttcaacaatg atacacaagc ccctacttgt gtccacctca aaagcagtag ccagtcgcgc
      361 ggctactgct tttactatgc tttttttaca ccagctctga tagcagctaa taacaaaaaa
      421 gattgaagac acagcttatt gggtccccga tctttttttg gtcatacaac caacagcagc
      481 tcttgaggct tgctgtcctt ctaagaggct gttggcttgt tgctttagct taattctgct
      541 acgatagcct tgatttgatc cttggtatgg acgcctgcta cttgcttgac aaccttaccg
      601 tcctttttga acagcagggt tgggatagac ataatgccaa attgttgagc agtattgggg
      661 ttgtcatcaa catctagctt gacaatctta agctcagctt cgtcaatttc tgctgctaat
      721 tgatcaagga ttggcgcttg cattaagcaa gggccgcacc aggttgccca aaagtccaca
      781 aggactaggc cttcattagt ttctgcttca aatgttgcat ctgttacgat atgtgccatt
      841 gtaatctccg ttcttatagt ttataagcct attttagggg aaaacgactg ataatgcaag
      901 aatctgatac gaagacctcg gtcttatgat ttaagaaaaa tctggcgtag ccattttaag
      961 acaaatacgc tggcctttgc tacaatgacc ttatcttaac aactaaaagg aggctactat
     1021 ggaagcatac gagcttattg tgattggatt tggtaaggcc ggaaaaactt tggctgccaa
     1081 aatggcgcag ctaggaaaaa gagttgccct tattgagcag agccccacta tgtatggcgg
     1141 gacttgtatc aatatcggct gtattccaac aaaggcctta atcactgctg ctgagcataa
     1201 tgctagcttt gcagacgcta tggcgcacaa agatactgtt gttcatcgtc ttcgccaaaa
     1261 aaatgagcag ctgctagctc agtctggtgt gacactttac aacggtaagg caagctttgt
     1321 ctctaataag acgattcaag tagaagcagg gcaggagcgg atcctcttag agggcaagca
     1381 tatcgtgatc aataccggag ctgtttcaaa tcgctttccg atacctggtc tagcagatag
     1441 tcagcatgtg gttgatagta cagggattct agctctcact gagcagcctc agcgcttggc
     1501 tattatcggt gcggggaata tcgggctaga ggttgccagt ctttatgcca gcttaggcag
     1561 cgaggttact atgtatgagg ctgcacctgc tattttaggg cgctatgagc cggttgtcgc
     1621 tgagctggca caggattacc tggaaaaagc tggggttacc tttaagctct ctgcgactgt
     1681 tgagctgatt gctaatgatg aagcaggtag agttctagtg actgctaatg gcaagacaga
     1741 agcctttgat tgtctcctct atgctatggg acgtaagcct gccactcaag gccttggctt
     1801 ggaaaacact gacattaagc ttgatgatcg ctatgctgtc gtggtagatg attattgtca
     1861 aaccactgtc gaggggctat atgcggttgg tgatgttaat ggcgggcctc aatttaccta
     1921 tacgtcctta gatgatttca ggattgtgtt tgggcagcta acaggcacaa gccagtacaa
     1981 ccacaaagat cggggctatc tgccaacaac agtctttatc gagccgccac tttcacaaat
     2041 tggtctaaca gaaaaagaag caaaagagca gggactgccc tacaaggcta atgagctctt
     2101 ggttgccaat atgccacgcg cccatgtcaa taacgacctc agggggattt ttaaggtcat
     2161 tgtcaataca gagactaatg aaattctagg ggcaacctta tttgctaaca attctcacga
     2221 atacattaac ctgattaaga tggctatgga taaccagatt ccatatacct atctcaaaaa
     2281 ccagctcttt acccacccgt caatggctga aaatcttaat gatgtcttta acctttaaaa
     2341 gaacctcaac ctcacctgca tagcaggtac aacagccaaa ctattaaaaa aacaaactcc
     2401 tttttggctg cttatcacat ggataggcgg ctagcaaaag gagcttgttt tttcttgtat
     2461 ccaatcagca ggctagcagc tgctcatggt ctaaaggaac tagctaggct gggacacgtt
     2521 ggtagcaaaa gtccagcaag actcactagc tgctgtcatg agctttgaag agcagcactt
     2581 agggaacacg cccagtagct ttctttggga cgcttggctc acctagggct caatcagctt
     2641 gagtaaaaag gggctttatt tgaatcaaga ggatcaatta gcctagatta gctatggtac
     2701 agcctgagcc gccagcattt tgcggggcat agccaaagct tttgacatgc ttgttgcgtc
     2761 gcaagtactt gccgaccgct tcacgtataa cacctgtacc aataccatgt atgatgtcaa
     2821 cctgactcat gttgttaagc aaggcttggt cgataaaggc atctagctcc tgcatggcct
     2881 cctcatagcg cttgcctcga aggtctaagc gagcgcgcgg cccttttcct gtagctgctt
     2941 ttttgacgac cttgacagct ctcttcttag gctgctgcgc ttcttctttt agcttaacca
     3001 agctgaattc gtcttccttg agggtcaact tgatcaggcc aacctgagcc tcccacctct
     3061 tgtccttaag ctgggcaagc aaggttcctc tttgcccata ggcggtaaca atgatgtcat
     3121 cacccacacg aggagcccgc cattttttcg cttttttcag caccttattt tgcgacaggc
     3181 tttgctctgg cgcaagctgc tttaggcgat gcttggcttc gataatttcg tgcggcttta
     3241 gctctgcctt ttcatgcagc tgacttaaaa tgctatcact ttctgccaag gctatatcca
     3301 caatctcacg cgcttcaagg gctgcctttt ccaattcctt gtccttagcg tgggagaact
     3361 cgttatagag ctttttaaca gcacgattga atttgaggtt atcctgctcg acctccttga
     3421 tatgctcaag gcgcttgcgg ctttctaacg tttgctgctc tagttgctca atgatacgat
     3481 tgacatcatg atcagttgcg gtcatcgcct gagcttcctt gacgatgtgc tctgctaagc
     3541 ccaatcgtct cgcaatgtca aaagcatttg agcgaccagg cactccttgc atgaagcggt
     3601 aagtaggctt taggctgaca ttgtcaaagg ccatgctggc attttcaaca taggctgtct
     3661 caatcccata ggcctttagc tctgggtaat gggtagtggc catcgtctta atattggtca
     3721 gacgcagctg ctccaaaata gccatagcaa ggctggctcc ttcctgtgga tcagtccctg
     3781 ctcctagctc gtcaaagagg atcaagctgt cactgtctgc ctgattgaga atctcaacaa
     3841 tgtgagtcat atgactggaa aaggtagaca ggctttgctc aatggattgc tcatctccaa
     3901 tatcagcata aataccatta aaaactgcca ccctggagcc cttgtcagcc aaaataggca
     3961 gccctgactg ggccatcacc tgagcaagcc ccaaggtttt gagcatgatg gtcttaccac
     4021 ctgtattagg accggtgatc acaattactg ctaagtcatt tgcaaaatgc agatcatttg
     4081 ccacagggtt ttgaatcaag gggtggcgcg cattgagcag ctgtaagctt ttatcgtcag
     4141 aaatcactgg cacagttgcc tgtttggctt gcatataaag gtattttgct ctcacaagat
     4201 ctaaatgtcc tagtagccaa gcgttattcc taagagatcg actatgcgga cgcagctgct
     4261 ctgacagctc atgcaagatt cgtccaatct catggcgttc atctgtctgt agctgagtca
     4321 gctcctcatt gagacttaca agcgctctag gctcaatgta gaccgtactg ccagaagctg
     4381 acatgtcatg cacaacgcct gccaccttat gacgataggt gtttttgaca ggcaggacac
     4441 ttcggccatt acgactagca atcaggctct ctgacaaata agctgcctgt ttttttagga
     4501 tatcctgcag gagctgacga ctggcatgct ccttgtttga tatctgacga cgaatgctct
     4561 ccaattcagg actagcaaag ccttcaacaa agcctgcgtc attaatggct tggagactcc
     4621 cctgtaagct aggaaagctc tctatttttt caaagagtgc ttttagagcg actaaatcaa
     4681 cattttccaa atcagcgtaa aaacgacaga cctctgccga cacctgcagg agctttttaa
     4741 ctgctaaaag ctcttgaatg ctcagatctg cctctaaatc caaacgctgc atgctttctg
     4801 agacatctga tagccctccc aaggcaaaat ggtggtgctc tacaaaaata gccgccattt
     4861 cctcaagctc tgtaaagtaa gcctgtattt tgtctttatt cgcaataggc tccaacaagt
     4921 caagctctag ctgcccctgc tctgtctgta aataaggcca aaattgctct ttaacctttt
     4981 caaattctaa ctgttctaaa atcttttttt ccatagttct tattatacct aaaaatcact
     5041 taaaatgtgg gacactaaac aaaaagagac cagagagact ctgacctcaa agaatagctg
     5101 ttacccataa ttgcctgaga atgcttgaga taaagggaca atgctcaacc aagaggcgag
     5161 acaaaagact gccatgtagg cgcccttgaa taaagggcat gggaatggta gcaagaacgg
     5221 tcaatgccat gcttaaaaac aaaaccgaaa ccatcaccgc cagcaagcca ctggctagct
     5281 tagcctcaaa gccatcaaaa taatccaccg gcgcaaggtg caccaagaca cccgccaatc
     5341 gaaccacagc atagcctact gtagacagta taaaaaatgc tatccctgca taataaacct
     5401 tatccaattc aaaaatatta atatccttaa aaaataaggt agctgctccc tcagcaggat
     5461 tagaataagg cacccataga gccagcttgc ctgccagagc cttatagcca tgatgggcaa
     5521 acaagagcga caccaaggcc ccaaaacaat aaaaggtctg aaggataagc cctctattgt
     5581 agccaatgta aaagctccaa gaaagcagta acaatataag cactgagagc atcatgacac
     5641 ctcatctgta tctgcttgac tagccttttc ctgaatacct gccagtgcct tctcacgcag
     5701 ctcgacaatc tcagcttcga ttttttcaat ctcaatctct ctactcagtt gggctgacag
     5761 ggtattgatg gtcatcaaaa tagcaacggt ttcgtcgtct gcttctggca gacgctcctt
     5821 gatggcctga tatttttcct ttgccacacg atcaacctct tccataaaga ggttgtcttt
     5881 gtccgttgtc aatgttaatg tcttctcacc aaatgttaat ttgtaacgat taatattctt
     5941 cataggctca cccctttagc attataccct aaaaatgact tttcgtaaaa ttgtgaaatt
     6001 aatctgagat tgcatggaat gatttcccat aacaggacat tttatgttaa aataatgttc
     6061 atggacacct tagttttcaa aatcaattcc caagtcagca gcagcctgat caagcagcta
     6121 gcaccatacc gcataagcaa tgccaatcct tacgttagac tggctgccaa aaaagatggt
     6181 gtcacactga tgctgtatac ctcaggcaag ctggtgctgc aaggcagaca ggctgcaaag
     6241 ctggctcaag agcttgatct gcaagaaacg cctgctgatc agagacccgc accctccagc
     6301 gcacaggata tccccttaat tggtagtgat gaggtgggaa atggctctta ctttggaggc
     6361 attgctgttg ttgctagctt tgtgcagcca gaggagcacg ccttgctcag acagctcggt
     6421 gtcgatgatt ctaaaaacct caatgataag agtatcgccc agatcgctcc tgtcctaaaa
     6481 aagcatattc aacacagggc gcttttgcta tcgcctaaaa aatacaatga aatggtaggt
     6541 aaggggaagc cctacaacgc tgtttctgtc aaggttgctc ttcataatca agcgattttt
     6601 ctgctcttaa acgacggagc aagaccagaa aaaattgtca ttgatgcctt cacaagtcag
     6661 gccaattatg acaaatacct acagcaagaa aaaaatcact ttcgtaatcc cttgaccttt
     6721 gaggagaagg ccgaaggcaa atatctggca gttgctgtca gctctatcat tgctagacag
     6781 ctatttttag acaatcttga caagctcagt caagatctgg gctaccggtt gcctagtggt
     6841 gctgggcgtc catctgatca gattgccagt caaatcttag ccgcctatgg tatggcaggc
     6901 ttagagcatt gcgctaagct gcactttgca aacaccaaaa aagcccaagc gctactaaaa
     6961 aaacaataat cttagaaaaa taaaggaaaa gtcatgaaac aatttattaa agaatgggga
     7021 gcttttaccc tttttatcct actttttgga ctctcacgtt tgttcctatg gcagcctgtc
     7081 aaggttgatg gccactcaat ggacccaacc ctagcacatg gcgagaggct cattatcttc
     7141 aacaaggcta agattgatcg ctttgatatt gttgttgcca gtgaggagga cgagaacgga
     7201 cagagaaaag agattgttaa gcgtgttgtt ggcatgccag gtgataagct gtcttataga
     7261 aatgacactc tttatatcaa caacaagaaa acaaaagagc cttatcttga tacctacctg
     7321 acgagtttta aaaaggacaa attacaatca acctatgctt acagtgatct cttccaagag
     7381 ctggctgaaa atgctgctgc ctttaccgtc aactccgaag gaaaaacaga atttgacatc
     7441 actgttccaa agggcgaata tttcctactg ggtgatgacc gcattgtatc tcgtgacagc
     7501 cgcgaggtcg gctcctttaa aaagcaggac atcgttggtg aggttaagtt ccgcttttgg
     7561 ccactcaata aaatcaatct cttccctaga tagcaggcaa gctaaagcta ttttctagca
     7621 gggctgatat aggctctatg cccacagcag taaagactca gggcagcaat agcctctatc
     7681 tatatctgct tatctatcca taccaagagg cttgatgtgc tatccaagca ctcagctagc
     7741 tttagagaag cagctattgt tgacgttcta aaacctgccg ttgtgcaggt tttcgactat
     7801 cttgcacaga aaggtaccgt catggaacac ttttttacag gcactgttga ccgaattatc
     7861 tttgacaatg cgtcaaattt tttcaaaatt ctattactgg ctatagagga tactgatagt
     7921 gattttgatg aagctgacat tgtcattaca ggcactatgg ctgagatcat agagggcgaa
     7981 gcctatacct tttggggtga gctgacccag cacccaaggt atggtcagca gctgcgcctg
     8041 agccgctatc aaaaggctaa gcccacctca gcaggtctcg ttagctattt ttccagtgag
     8101 catttcaagg gcattgggca aaaaacagct gagaaaatca ttgcccttta cggtaataat
     8161 cctattgatg agattttaaa aaatcccagt cggcttaatg agatctctag cctttctaag
     8221 gctaatcgtg aagcctttgt ggcaaagctt aaagccaatt atggcactga gcaggtgatt
     8281 gctgccttgg ctgatctagg actggccaat cgctttgcct ttcagctatt tgacaaatac
     8341 aaggaagagg ctgttcatat cgtcaaggac aatccttatc aactcattga ggacattcaa
     8401 ggctttggct ttaagctggc tgatagctta gctgaacagc taggaattga gagtgcctct
     8461 cccaagcgct ttcgtgcggc tctgctgcat tgcctgttgg agcaatccat caagcgaggc
     8521 gacacctata tccaggcacg tgagcttttg gcgctgacca ttagcctatt agaggacaca
     8581 aggccagtcg aatgcgaccc agctattgtc gctaatcagc taacccagct catcgacgag
     8641 ggcaaggtta tgactattgg cacgcgtgtt tttgacagca gcctttatta tgccgaagac
     8701 ggcattcaaa agcatctgac acgcttacta cagcagcctc tgactaagga gcctagtcaa
     8761 gataccattg accaagaaat ccaagccata caagaggagc ttgctataac ctatgacaag
     8821 atccaaaagc aggccatcag ccaggcactg accagcaagg ttttcattct aacaggaggc
     8881 ccaggcacag gaaagacaac cgttatcagg ggcattttac aggcctatgc cagcctgtac
     8941 cagattgacc tgaaacaaaa ggatattccc attatcctag cagctccaac tggtcgagcc
     9001 gctcgtcgta tgaacgaatt aaccggtcta gcaagcgcaa ctattcaccg ccatcttggg
     9061 ttaaacggag acaatgatta ccaagcaatg gaggattatt tagactgtga tttgctgatt
     9121 gttgatgaat tttccatggt tgatacctgg ctggccaatc agctattaac agccatcaat
     9181 tctaataccc agctgatcat cgtaggagat agcgaccagc tgccttctgt cggtcctgga
     9241 caggtactag ctgacttgct aaaggttgat cggatccctc acattaccct tgacaagatt
     9301 tttcgccaat cagaggagtc aaccattgtt gatttagcca accacatacg ccaaggcatt
     9361 cttgctcctg atttttgtca gaaaaaggct gatcgctcct actttgaagc gcaagcgcca
     9421 ttcattcccg gcatgatgac aaagatcgta caggctgccc taaaaagtgg catcccagct
     9481 gaggaaattc aaatcctagc ccctatgtac aaaggactag caggcatcaa cagcctcaac
     9541 cagctcatgc aaaacctcct gaatcctcta gctaatcaga cagaatttct ctttaacgag
     9601 acggcctttc gtaagggaga caaggtactt caccttgtca atgacgctca gcttaatgtc
     9661 ttcaatggtg atattggcta tatcacagac ctcattccag ccaaatatac cgaatccaag
     9721 caggacgaaa tcatcatgga ctttgatggc accgagatcg tctacccaag aaatgaatgg
     9781 ttaaaaatca cccttgccta tgccatgagc attcacaaat ctcaaggcag tgaatttcag
     9841 gtggtaatcc tgcctgtcac ccgtcagagt ggtcgacttc tgcaaagaaa cctcatctac
     9901 actgccatca ccagatcaaa aagcaagctc atcatgctcg gagaaatagc cgcctttgaa
     9961 gaggcaatca aaaaagaagg tgacaagcga cacacctatc tcgtacaaag gcttcaagtg
    10021 gctgaagctg atgaccatac agcagctgct tcagtaaagg aatcaaatca gtctagccta
    10081 tctgtaatgc cagctaccag cccacaaaag gaacaagagc agcctcctta tctgctcacc
    10141 cctcataatt tcctagctat agaccccatg attggtctaa ccgaagatga tatgttaacc
    10201 ttttttaaga aaaaatcata atatattaaa aaagtaaggc acaatcctta ttcctatgct
    10261 ataatatcca tgtatcatct taaaagtaca ataacataac attcaaggag acttatatga
    10321 tttcatacga acaagtacga caagcactca gaacatcaac tattacgatc attatcatca
    10381 atgctatcag catggttatc accttgtttg gacttgctgg cattttcttt ttgaagtctc
    10441 aattggataa acctgaattt cgtgcacaat tttcagctga gcagctaagg ctatttgagg
    10501 ttggcatatc accctttact atttttatgt cagtgattag ccttggattg gttgttttga
    10561 ccactgtgct ttgtggcttt aacctctcaa aaatcaaaca aggttccact gtcagctatg
    10621 ttccttacat tatagggatt gtgctctatc ttattagtat cgtaagccaa ctatttagcc
    10681 aaattgagcc tgtctcaatg atcattgtcc tagctgagct tgcgctttac ggctttgcct
    10741 tttacaaggc taaaaccctt aatgaaaaag acaaggacaa tccccaaagc attgaagaat
    10801 aagcaggcca taaaggtatg ataacaagac ttcctgtctg ccttcaaata tggctctttg
    10861 tcagcccact acggttgaca aagagccttt tttaaccact aaaaaagcaa gaggaaaatt
    10921 gataatgtcc tcttgctttt tttgttagtt gaatgacagg tccaacaaaa tatctgtcac
    10981 tttatccttt agtccggtca ttgtgactcc caataagcgg attcctgcct gatgctcctc
    11041 caggctatca aaaagctctc tagccacctg atcaatgatc ctagcatctc ttgttaactc
    11101 aggtaggcta acccgcttgg tcaaggtcgt aaagtcagca taccgaacct tcaaaacaat
    11161 gatccttcct agttttttat tcgcctcaag caaatcagcg acccgtcttg catgtttaga
    11221 aagctctgcc ttaatatcag cctcctggta gaggagctta gcataggtac gctcactgct
    11281 gatggatttg cgcatacgat taggcttgac tggagaatga ctaatgcctc tggcctttcg
    11341 ataaagctca tagccaaagc gtccaaactg atcaatcagg gtcatctcag gaacacgcaa
    11401 aagatcctgc ccagtgtaaa tccccatctc atgcagcctt tcaactgttc gcttaccaac
    11461 gccatgaaac ttttcaatcg gaagcttttc taagaatggc agagcatcat caggaagtac
    11521 tagggtcaga ccatgtggct tttcaaaatc actagctagc ttggctaaaa atttgttata
    11581 agaaacacca gcagagcagg tcaactgcag gctattccaa atatcatgct gaatcagtct
    11641 tgcaatcttt aaggcagact tgatgcccag cttattggtt gtcacatcta aataagcctc
    11701 atcaatagac acaggctcca cctgatccgt ataacgcttg aaaatctctc tgatatcata
    11761 gccaatccta cggtacttag catgatctcc agagataaaa atagcctgag gacaacgctc
    11821 gtaggcctcc tttgagctca ttgcagagtg aatgccaaac cttcttgcct cgtagttaca
    11881 ggttgataca acgccccgtc caccactttc tctagggttc ttgccgatca ccaccggctt
    11941 gccctttaat tcgggattat ctctttcttc caccgcagca aaaaaagcat ccatgtcaat
    12001 gtgtataatc ttgcgtgagg tgtcattaat cagcggaaaa ataagcatag gtccctccct
    12061 cctacattat actcctttag gcttttaaag ccaaggcaga ggattgtatg acagttttca
    12121 actgtttcag caaactgtaa tataaaagaa tcttgtattt gtcaagattt ttgcttggga
    12181 aatcgtttcc cctatggtaa acttagattg taaatgtaac agattggact tgttactaga
    12241 ttttaaggag aaacttatgg caactgttaa aactaacgca gatgtttttg aaaaagcttg
    12301 ggaaggcttt aagggaactg actggaagga aaaagcgagt atatctcgtt ttgtacaggc
    12361 taactataca ccttatgacg gtgatgaatc attcctagca ggtgttactg agcgttcatt
    12421 gcacatcaaa aaggtcattg aggagactaa agctcactac gaagcaacac gcttcccata
    12481 cgatactcgt ccaacctcaa ttgctgacat tcctgccgga tttattgaca aggataagga
    12541 attaatcttt ggtatccaaa acgatgagct attcaaattg aacttcatgc caaagggtgg
    12601 tatccgtatg gcggaaacaa ctctgaagga aaacggctat gagccagatc ctgctgtaca
    12661 tgagattttc actaagcatg tgacaacggt taatgacggt attttccgcg cttacacgtc
    12721 aaacattcgt cgtgcgcgcc atgcccacac tgtaactggt ctgccagatg cttactcacg
    12781 tggtcgtatc atcggtgttt acgcacgtct tgccctctac ggagcagatt acttgatgca
    12841 agaaaaggtc aacgactgga atgccatcac tgagatcgac gaagaatcaa tccgtcttcg
    12901 cgaagaaatc aacctgcaat accaagcact tggcgaagtg gttaagttag gtgatcttta
    12961 cggtgttgac gttcgtcgtc ctgctgaaaa cgtcaaagaa gctatccaat gggttaacat
    13021 tgcctttatg gctgtttgcc gcgtgatcaa tggtgctgct acttctcttg gacgtgtccc
    13081 aatcgttctt gacatctttg ctgagcgtga ccttgcacgt ggaaccttca ccgaatcaga
    13141 aattcaagaa ttcgttgatg attttgtcct caagcttcgt accgttaagt ttgctcgtac
    13201 aaaggcttat gacgctcttt attcaggtga cccaaccttc atcacaacct ctatggctgg
    13261 tatgggtaat gacggtcgtc accgcgttac aaagatggac taccgcttct taaacacact
    13321 tgacaatatt ggtaactctc cagagccaaa cctaaccgtt ctttggactg ataagttacc
    13381 atatgctttc cgtcgctact gtatgcacat gagtcacaag cactcttcaa tccaatatga
    13441 gggtgtgaca acaatggcta aggacggcta cggtgaaatg tcatgtatct catgctgtgt
    13501 gtcaccactt gacccagaaa atgaagagca acgtcataac attcagtact tcggtgctcg
    13561 tgtgaacgtg cttaaagccc ttcttactgg acttaacggt ggttacgatg atgtgcacaa
    13621 ggactacaag gtatttgaca tcgaccctgt tactgatgat gtccttgact ttgatactgt
    13681 taaggctaac tttgaaaaat cacttgattg gttgactgat acttacgtag atgcgcttaa
    13741 tatcattcac tacatgactg acaagtacaa ctacgaagct gttcaaatgg cattcttacc
    13801 atcacatcaa cgtgctaaca tgggatttgg tatctgtggc ttcgcaaata ctgttgacac
    13861 cctatcagct attaaatatg cgactgttaa gccaattcgt gacgaagatg gttacatcta
    13921 tgactacgaa acaatcggcg actacccacg ctggggtgag gacgatcctc gctcaaacga
    13981 attagctgag tggttgattg aggcttacac tacacgtcta cgcagccaca agctttataa
    14041 gaacgctgaa gcaactgtgt cactgcttac catcacttca aacgttgctt actctaagca
    14101 aactggtaac tctccggttc accgcggtgt ttacctcaac gaagatggta caactaacct
    14161 atcacaactt gaattcttct caccaggtgc taacccatct aacaaggcta agggtggctg
    14221 gctgcaaaac ttgaactcac ttgcaagcct tgacttctca tatgccgcag atggtatctc
    14281 actaacaact caagtatcac ctcgcgcgct tggtaagaca catgacgaac aggttgaaaa
    14341 ccttgttact atccttgatg gttactttga aaatggtggt caacacgtta acctaaacgt
    14401 tatggactta aatgacgttt acgataaaat tatggctggt gaagacgtta tcgtccgtat
    14461 ctctggatac tgtgtcaata ccaaatacct tacaccagaa caaaaaactg aattaactca
    14521 acgtgtcttc cacgaagtgc tttcaatgga cgatgccgct gaagctattt caggaaaata
    14581 agctaatctt agctagctaa gagcctgtct gttgacaggt tcttttttta tcacacatgc
    14641 aataggtaca gctgtcctca gcagctgaat aaccagcaga gctggttgaa actactagca
    14701 agcctatcat tatcattgtg aaaatcagac gattaacctt ttcattaaaa aaaaaaaaac
    14761 gaaactacgg agaaaagctg atgaggagct ctttaaggct atcagtcaac atgttaaact
    14821 cttcttagga agcgttaaca ataactaact gctaagctaa gcaattatct attaaggaga
    14881 ataacaatga aacgactaaa aacactatgc ttgttagcta ctgctataac cctaacccta
    14941 gctcctatca gcacaagcca gacaacaaca cagaccgtat atgctagtga aactcatcaa
    15001 aatctttgta cgaacactgg taacggatgg tttaaatgtc ccgatggaca tggagggtgg
    15061 acttggcatt ttgacgaaaa tcataagtca aatcagcagt cctttttggg aggattgttg
    15121 ggctttgctt tgtctctatg gggagctatt attagactct tttaagctct agcttaacta
    15181 atcctcaaac aacaaaaata agctcttaga gaactaagct ctaagggctt tttgctgttc
    15241 tgataagtaa aaaccaagag acaaggacat caaaaacaag caggcctatc agatatacca
    15301 cctgataggc ccacttgtgc tctcattctt atctaggact atttctgtca aaggtcctat
    15361 gaatagcatc ccgaagctgt cgtctctctt tgatccacaa ggccctatca tccttgtcat
    15421 aggttctatt ggtgagaaaa atcgctgcct gctgctcctt tttattgagc atgataaaag
    15481 gccctgtata gcctgtatga ctaatccaat caccctctag gctccaaccc aaagacctgg
    15541 gcttttcctg tctgctatag ctttgaaaaa gtctatccga aaagctttcc ttcaggtaat
    15601 gctcaataaa ccgctctaaa tccctgatgg ttgaaaaaag ccctgctgag cctgcatggt
    15661 ttcccaagac cttagccttg ggatcatgta cctctccatc aagcacccct ttgaccgttg
    15721 gaactgcttc tggccttggg ccaaaggagg tctcagtcat tccaaaggga gtaaaaacca
    15781 tctcctgaaa aagctcatca agagactttc catgaaggtg ctctagcatg aagccaagca
    15841 ataaaaaatt cacatctgtg taatgaaagg tcttatcgtc cttgacctga agctggtgca
    15901 tcgctgctct taattgctgg gcattgagct gatctcgatt gggaatataa gggtcaagtc
    15961 cactagtatg ggtgagtagc tgtcgcagtg taacctccag cttttgagcg tcaggataat
    16021 aatgccttaa aggagtatca agagccaagg caccactatt gatcatggct atacagacag
    16081 tcgctactcc gacaacctta gagacactgg ctaaatcata aaccaagcct ttggtaacag
    16141 gtctttgacc atcaagggta ccgatataat gctcctgcca accgccacag cgaaaaaggg
    16201 ctaagctagc cccatgatat aagccttcct gaatctgctg gcttaccttt tctatgactt
    16261 ctaatgtcat ttgacaaacc aaatttcgat ctgacttggg tctgaaagaa caagcaccct
    16321 tgccttttta tctaaataaa cctgacaccc tttgtcctca aggtaggtct ttagagcaag
    16381 caagtcatag ctatctgaca cctgaaattc taaaatctcc aaatcccatg tgacatgcgg
    16441 gacaatcgtc aaatcttgac cagcctccct attaaactca agcgtgaccg gcaggcaatc
    16501 accaaaaata gactgataaa aagctctgga ttgctcgtca tctaaaacat ttaagacaat
    16561 cagatcaaag ctaaactgac tcagccccct aaagtcagct tccttgtcaa ttgcaggaac
    16621 atcatcgaca atgtcaagct ccttgatatc gtcctctgca tggagtaaga agcgatctcc
    16681 ctctggtgag gtgacttcaa aggcatagcc tttttttccc ttgaaaatca aatcatagtc
    16741 aacgccatga gctaggagct gctcaatgtc cttaggagca gttgttttga taacaattgt
    16801 atttactttc ttagggccat ctacaacgcg tgttcttgct gctggagatt cttcaattac
    16861 aaagcgttct tgtccttggc cccaagatga aaaaattgat atcgcgtttt cctctgacac
    16921 tagccttaag cctagatttt tttggtaaaa ggcaatatta aggtcgcgat tgttaacacg
    16981 taatactggg gttttaaaga caatattgtc aaataaagtc atatattcct cctaatcctc
    17041 tgctattata gacaaaattc caatttttga caagaaatta tatgcttttt aaccgcctgt
    17101 cacgcgctac caaggcaata tagcactcac agccatcacc agacttacta ggtccaatct
    17161 tccttcgtgc gctctatcac aagcagcttt ccttagcgta actcatgcac atattggtaa
    17221 atgcgacttt ttcaaaatag cacatgaagt acccctttaa tttgactttt ccttaaccaa
    17281 aagcgagaac cttttttagt tctcacagta gcaatcacac tcttgaaatg tgatttcgct
    17341 ctcctcaata acagatgata actgaaattg cccggatttt cttatccacg cgcaacttca
    17401 aaagcacctt atcttcagca ttagtaagga tactaccagc ttagctcaga ccagattcag
    17461 ctggctcttg ctggcaagct tttatcacaa aaaagaaggc ctaagccttc ttttttactt
    17521 gatataaagg aatttgaatg ctgctactgc tgctactgct gctagcactg gggcagcaac
    17581 cggtacccat gagtaccacc attttgaatc ccccttggct tgtccaagga ctgattttgg
    17641 taagaaatgg tgaaccaaac gagggcctaa gtcacgcgct gggttgagcg ctggaccagt
    17701 aggaccacca agagaggtca caagagtcat caccaagaaa ccaatcccca agtgagctac
    17761 tgcaagtgag cctgtcacgt aaggagagat ttgcgttgca gctgttgttt ggtcatagcc
    17821 agcctctacc agcttaccaa caagctccac accaaagtaa ttcttggtta aggccattgc
    17881 gccaaaaaag aggacaaagg aaccaacaaa ctcgttcaaa aagccattaa tgtaggctgc
    17941 cttacggctg ctcttgtcac catcatcaac tgctgaaatc gttgagaagg atcccaaaat
    18001 attgttaggg ttgtctgtct gcacaaaata aggcttgtac accgcaacaa ccactaattg
    18061 gccaaacata gcccctagca attgagcaag aacatattgt aaaacgtgtg cccaagggaa
    18121 caagcctgaa actgccaagc caaaggtaaa agctgggtta atgtgatttc cagaaacgtt
    18181 accaaacata agtgccggca tcatcacacc gaggccatag ccaaaggcaa tcacaagcca
    18241 gcctgagcgg ttaccctttg ttccctttaa gtcaacattg gcaactgctc catttcccaa
    18301 aataatcaaa aatgcagtgg caataaactc tgtgatgtat ttcacagtcc atgttatttc
    18361 catattctct agtttcctcc aaatgataag tataacagat accattttat cagggatact
    18421 agttcttgta aagcctattg taagatattg cctgcttaat atgtttacag tgttttttca
    18481 caattacgga caactaataa gtctttttta gcatgtcgca ggatatactc tgaggtcgat
    18541 ccaatcagca gacgctcaaa ggtatttaag ccagttgctc ctaccatgat caaatcagcc
    18601 tgctcctttt caggtatgtc actagctaag agctttttag ggttgcctct ttcgatgatt
    18661 tttttaatgc tgctaacgcc tctgcctcta gccattttct cgtaatagcg caacacctcc
    18721 ttggcatgct cctcttgtgt gtcaaagaca taatcactaa ccattgcatc accctgatag
    18781 gccttaacat caataacatg agccagcagt aagaccgcat cattgcgaag ggcaacatta
    18841 atggccttct caacagctaa ttctgattcg taagagccgt ccaccgcagc cagaatccgt
    18901 ttatatttgc ttatcatctt tgtctccttt cgttgattag cctttatcaa tagcctttgc
    18961 ttgtgtcttt aggaaataca tgactgcgca ggcagctgga atgagccctg ccagccagaa
    19021 caattgatga aaggactgca caccagaccc aagaagcata tccttgatga gtcccaacag
    19081 ataaggtccc gcacccaagc ccaaatctag cccaatcata taagtagaca tagcggtatt
    19141 aaagcgatgc tcctcaaccc ccttgatgga ggctgcctgt ccgcaggaca taaaggttcc
    19201 atagccaaag cctatcaaag cacccgaaag cagataggga aggctgcttg tcacactacc
    19261 aagcaggaaa agccctagcg ccaaaaagag atagctggga taaagaaccc actgctcccc
    19321 cttaacgtcc atcaagcgtc ccatagcagg tcgtgtgatc gtaatgatca aggcatatac
    19381 cacaaagaaa taggctccca ccgtcgtcaa atgaatgtct gttgtgtata atttttgaaa
    19441 gcctagcaca gaagcatagg caatccccat caaaaaggca atcaaggtga taaataaggc
    19501 ctttcgctca ataaagctat caactgtcca ggattttgtt tttgccagct gctctgagtt
    19561 gagggcaata tctgtcacag gaaaggcaaa ggcccctagc acaactactg cgatcaacac
    19621 actgcacaaa ataataatca tccgaaaatc aatgtgcaaa ttatccagca taaaggtccc
    19681 aacaaaagga ccaatcgccg ccgctaggct tgttgataga ccataaaaat taatcccctc
    19741 tccgcgcttg ctagctggaa tataggcagt cacaatggta ttggttgctg ttgagacaac
    19801 accatagcca aagccattaa acaagcgcac aaaatacatc atgccaatcg ttggcatgaa
    19861 aaagtaggct agcgttgtta ggagataaaa aatggcgcct cctcttagca ctaagcgtcg
    19921 gccaaaaacc tccaattgct tgccaaaaat cagtcgagcc agcagggttc ctaggatata
    19981 aatccccgtc gccagacctg cctcactggt cttagctcct aattccttag tcgcaacaaa
    20041 ggcaatgatc accgtaaaca agtaatagac catatacaca ataaaattta atactgtgat
    20101 ccctataaaa tgcttgttaa ataatttgtc ttccactgaa aatgagctcc tccctatttc
    20161 attaacattt tacaaaaaaa tcagataatg ccccatttca atggtataat ataggtgata
    20221 ctattaaacg acattagcaa atgctaagca ttgctgcagc aacaaattat ataatgatac
    20281 cagaaacacc tctaggagaa aagcgtgaac catcaaatct tacagcgtta tattgacagt
    20341 cataactttc ctattatcga aaagggctac cacaaatacc tgacctttga aagcttagag
    20401 gaggatttta cgtatatcct aaaggagggc attgtcaagc aaagcgttct gtcaaaatat
    20461 ggcatggaat ttaacctcag gtacgtcaca ggccttgaga tcacctctgt gcttaatact
    20521 ggctattcca aggacatgag agagccctac aatgttcgca tcgaatctga gactgccagc
    20581 ttttataagg ttcgtcattc caccttttta agggatatta gcgaggatat cgagctgcag
    20641 ggctatgtca aggactttta tcactaccgc ctccaaaaat caatgaaaaa aatgcagtgt
    20701 atgctgacaa atggccgtat cggcgctatc tctactcaga tttacgattt aatgaccctt
    20761 tttggacgcc ccttggctaa tggccatatc cttattgatt ttatcatcac aaatgaggag
    20821 ctgggcaaat tctgtggcat ttcgactgcc agcagtgtca gtcgtctcct aaagcagctc
    20881 aaaaaagagg gcattattca aatcaatgac cagcatatca tcattaccaa tttagagaag
    20941 ctaaaggata atattgtttt ttaacgattt agaaaggacg tcccatgcgc tataatcaat
    21001 tgtcttacat tcccaccagt ctagaaacag ctgtagctga gcttcaggcc ctgggctttg
    21061 ctgtccagca agagcaagca cccaaggaga acttcgctat tttccttaga aagctatttt
    21121 ttcattttca ggataccgat tatcccttga gccatatgat tgcaagcaag gatctcgacc
    21181 tattgacctt tttaacatct gatgcaacac tgacaaaaga ggtttttgat ttagtggcct
    21241 tacaggtcct tggctttatt cctgctgttg actttaccga tgcacaggac tttatacaaa
    21301 agattggctt tccgattgtt tttgacagcc agcaattact actcaattta catcagctgc
    21361 ttgcaacccg gcagaagtcc ggtgtgacct tgattgatag ccttgttagt cagggcttgc
    21421 ttcctatgga taattgctac cactacttca acggaaaagc cctagcaacc tttgatacca
    21481 ccagcctcat tcgcgaggtg gtctatgtcg aagcgccact tgataccgat caagacggac
    21541 agcttgacct catcaaggtc aacattatcc gccccaaggc cagcactgct atcccaagca
    21601 tgatgacagc cagcccttat caccaaggga ttaacgagac cgccaacgat aaaaagctcc
    21661 atcgcatgga aggtgagctt agccctaagg ctcctcgtag gattaccgtt gagccaactg
    21721 attttcagcc gcttgccacc aagccctcaa ggcttcctgt caatgagtgc caagagacct
    21781 tcagccatat cagctcctac acactaaatg attattttct agcgcgtggc tttgccaatc
    21841 tctatgtctc aggagtggga acagcaggct caactggctt tatgacaagt ggtgactacg
    21901 cccagatcga aagctttaag gctgttatcg attggctaaa tggcagagct actgcttaca
    21961 cgagccacaa gcgtgactat caaatcaagg ctgattggtc aaatggctta gtcgcaacaa
    22021 ctggaaaatc ctatcttggt accatgtcaa caggactggc tacaacaggt gttgatggct
    22081 tagcagtcat cattgctgaa gctgccattt cttcttggta cgattattat cgtgaaaatg
    22141 ggctggtatg cagtcctggt ggctacccag gagaggatct cgatgtgctg acagagctca
    22201 cctactcgcg taacctgctg ccaggtgatt acttacgtca caacgaccat tatcaacagc
    22261 tgctgagcca acaatctcaa gctctcgagc gccaatcagg caactacaat caattttggc
    22321 atgaccgcaa ctacctgcca caggctgatc gcatcaagtg tgaggtcgtc tacacgcatg
    22381 gcctacagga ctggaatgtg aagcctagac aggtctacaa tatcttcaat gccctgcctg
    22441 atagccttgg aaagcacctt ttcctacatc atggtgagca tgtctacatg cacaactggc
    22501 agtcaattga ttttcgtgag gccatgaatg ccctgctctg tcaaaaaatg ctaggacaaa
    22561 ataatggctt taccctacca acaatcatct ggcaggataa ccaaaaagaa caaacctgga
    22621 aagagctaac agcctttggc ggtcacagca agcgtcagat tgccctaggc gatgatcatg
    22681 tcttaattga caatcactat ggcgaagagg actttaagcg ctatagcaag gattttcgtg
    22741 cctttaaagc tgagcttttt gaaggcaagg caaatcaagc agtcattgat attctgttag
    22801 aagaggatct accaatcaac gggcaagcct gccttaagct taagctaaaa tcaagtgaaa
    22861 acaaggggat tttggctgca cagctcctag attatggcaa gaaaaaacgc tttgctgata
    22921 tacctgctat tcttgagcta gacagcattg acaacgggca gcagtttgca cgtgaagcgc
    22981 tcaaggagct tcccttcaag gacagcccat accgcgttgt caccaagggt gtcctaaacc
    23041 tacagcaccg cagcgaccta ttgaccattg aggatattcc aaatgaccaa tggatgacca
    23101 tcaccttcca cttgcagcca accatctatc atatggccaa gggagacacc ctaagagtcg
    23161 ttctttacac gactgatttt gagcatacaa tccgcgacaa tagcaactat gccctaaccc
    23221 tagatttgga gcaatcctat ctcctaatcc ctactgatga ggaggaataa atcaaagcgc
    23281 atcaaaaaag cctgagatca caatgagctg caccccaatc gttagatcct ttgtctaact
    23341 gttggagtac agctcaaagc tctaggcttt tttaactatt ttgaaacctt tttaccagcc
    23401 tcagcaccag aatgcaggct gtagacggac tcgatatgaa tcaagcctgc tgcctttggt
    23461 gcgcccatct tgccttctgc ccattccttg gcagcctcaa agacaggacc ctctgtaatg
    23521 atttccgcac gccctacaaa gcgataacca cgcaattgct cgcgattgac ataagcgacc
    23581 tcaattttac cattagcctg aatattagag caggtttggc cgccagtatt ttcattataa
    23641 accaaggttt catcgtctaa cagtctcatc gaacgcttag ggccaatatt aggattaccc
    23701 tcattatcta cagttactac cattgctaat tgctcagcaa tcatttcttt catttcttct
    23761 gttaacatat aatctcctct taatcgtttc tatagtcagc tgactacgct ttgattatag
    23821 cacagttaag cagaaaagcc gacaaaaata ggttagctta aaaaagtttt acagtttact
    23881 taagattaga atgattctcg ctatctagcc atcacccttg atcacagtaa aaaggcgatt
    23941 agcaagcaag cactctttat ttcataaaat ccgaatcgtc gcccaaaaaa aatatcatca
    24001 actgatatgg tcaatgcctc tgcaatacct cttaattttt catacttagc tcgcctaagc
    24061 ttttgcacat ccttttcata tctggctagt gtcctaacag aaatcccagt taacgctgac
    24121 agttcctttt gggtcttttt ttgagcaatc ctcaattcct ttaacgttgc ttttgacaat
    24181 attttccctc cgcctctcat ctcaggtaat attaatgaca gatgacaagt ttattataga
    24241 cttcggtttt tatgaagtca agtcttttat cgcactttcc ccacttcttt ttctaaatct
    24301 tttgatttag cttgatttgt ggtatcatat cctatataga aataaaggag aatggaaatg
    24361 tccgaaaaga aaacattttt tgcaactaat ttaaaatatc ttcggctaaa aaagaatatg
    24421 gaacaattag aacttgctaa ccttttagga cgaaaaagct cttcctcaat cagcgaatga
    24481 gaaagaggaa agtacactcc aaaatctggt ctcctgagtg acattgctgc catctttgat
    24541 gtcagcctga cagacctcat ggaaaaggat ttaacactgg aaaataaggg agtgacttat
    24601 cagcttcccc aaagagattt agtaatgatt tcagagcagc tatctgaaaa caattataac
    24661 aaatggctgg attttggtca ggatctctta tctcatcagg ataaagaaga aaatcacaag
    24721 ccaagcaaat aaagagcctc acacgtctta ttctcatcaa gtttcgaaaa atcacctacc
    24781 actcaagcac acaaaaagcc ttggcagggc ttctaagcat aagaaagctg tatcatatca
    24841 atacctcagg gaccatgata tgatacagct ttttgtatct cacttttaga caaggtagcc
    24901 acataaagct tgcagatgac ctacctctgt attagctacc acaaccaaca gctagctaga
    24961 ctggcaggcc ctctataagc ctcagcggat tatctaagca ctcccaacag ctccaacaaa
    25021 ataaagacat aaccaatacc attatttaag atatgggcta ctgttgaaaa atagatattc
    25081 ttcttccaaa cataaactaa gccgagcaaa agtcccagtc caccatacac aacgatggaa
    25141 gatagctcgc tgaaggaata gatatgaacc aagccaaata gcaatgatga tcccaacaat
    25201 cgagccagca gcatacctgt gcctgattgg ccctcaccga ttaaaatctt gcggaaaata
    25261 agctcctcat tgaagggacc aataatactc accaccagaa taaagatcac tgtctcgaag
    25321 ccctcactag cattatagcg attagctaaa acagctgcat tgctgctctc ttctaaagga
    25381 aggctactga gcaaaatatt tgcaacataa agcactgcaa aaatgaccaa gacccacaag
    25441 gtatttttga cccattttgt tgaaaactgc cgccagtccc tctgataatc tgctcgataa
    25501 agccaacaga tcccaagtgc aaaaatcagc agatgtctcc cgtaaaataa aaaggtattc
    25561 aataaaggcg gaagctcaat cacattgcta acttgtctat aaagatacac agcaatgata
    25621 tatagcatga ccagtacagc tgcacgatga cgtttgatgg tatccaatta ctcttcctca
    25681 attctaataa ttgtcagatt agctaggcta tattgccatc agctaatctt gatcttaaat
    25741 gtgactaatt tacaagcact caacttttga atcggtaaag ctgacagaca gccctaccct
    25801 agcttcaata aagctatctt ccaatagtcc ttgcgctcat cagaactgtc aaaggcctga
    25861 cccagctgag tcaacagact tatccagtca acatcacaca gaacaagacc atcttaccat
    25921 atccctgcca actataaaag cccctaacct gacctatttg actactaaca gcaaaaaagc
    25981 agcttaaaaa caccaatcag acgccaccaa ggactcttga tcagcgcagc tcgcacagac
    26041 acctgaaaaa tgacagacaa gcctcttaaa agcacctcag caagctgagc caacccttca
    26101 cagaatagac aaacaacaag agctaagtca agacctcaag ctagcagatt acaggcagag
    26161 acgcttgcaa ggcttaccca gcaaaaagca acagactgat aaaggattca caccacacag
    26221 ccacaagtca agcagctagc ccaaacaaag cactgctcac caaatcctac tatgctttct
    26281 ggtagccctt atccattcaa aatcgtatcc aaggcttctt gatattgctt gtctcgcaat
    26341 tctctgatca cctgtgataa atactctgcc tgatacatca caaagtcaaa attgaaatcc
    26401 agaattttgg tgttctcatt caatgacagc ctctcctcga taaaagcagt catctcagct
    26461 gttgtcacaa tcaagtcaaa atcagttctc caaggcaatt cagcctctga caaaatatta
    26521 aaacgataga cctttgcaac acaaggactc acctgttgca tgaccaagct atataaaata
    26581 tcaatgtttt tcttgttgat ttcgatcact gctatggcta aaggtggcag accttctcta
    26641 acaagctgtt ccagtcgcgt gcaaagcaaa tgcaaattag agcctgtcag ccgaccaaca
    26701 ccagaaaccc gctctgccca gctattaatc atcagctcga tacgattggc caagagctta
    26761 ctgccttgat attcctccgc ataataatat ttttgcggga taaagagcga caaatcaaac
    26821 aaggtcttac gaaaataagg aatcaaggtc tgaatacaag ccttgtcaaa ggcgatatag
    26881 tggccaaaca attgacgcag ctcacccagc agctcttggt aagcaggatc ctcctgaatg
    26941 atcgtcaata aggccgaaga atcctcctca gaccattgtg tgatcgaaaa agagttgtta
    27001 accgtcaaat aaacgagaaa aatataatca atctcgctac tgggaaagtc catatcaagc
    27061 aacaatttcc cctcacgctt gaaaaagtcc tccaaatacc cataaagcgc caaagacttt
    27121 aagcgtttaa aaatcccctc ctgaggaatc gcaacgtcaa actctccacg cttccaagat
    27181 agcgacaaga gcacatcaaa aaagcgaaac ttcttatcca gtaacgggtg aggcgtttgt
    27241 tgctttttga tcgaaaagat aaagtcatgc acaatatcca gatcatggtc agtcagctca
    27301 tagatgacaa tcccgtactt atcatgcaat aaagcaatca aatagcggat acgccactcc
    27361 tcaccaacaa cactattatc ctctaaggcc aagccgcact cctcaacaaa gggcttcatg
    27421 tgctgaatca gccgataagc tgacggtgtg gaaataaaat gctccctagc aaagcctgag
    27481 acagatttga ccttatagca aggtgccttg atcaagagaa atttaagaat gtgcagccgt
    27541 accgattggc ggtaaatcgt cttcaaaaac ggtttgcccc ttttcaaaac ggtgcagcgg
    27601 acaatggtgc tatcccactc aaaggcgata tctccttgga aaagctcctc taattggtgg
    27661 atatagcgct ttatgttagc taggctaaag cccgtctttt gctgaatggc gtggaaactg
    27721 atcctttttt taccaagtag tatggtcagc agcaaagcct gatgattaat cactggttcc
    27781 aaatactctt caagcaaaac actttctcct ccttaaacca tttcgttagc gtcattatca
    27841 taacaatttt taccaaaaaa gtgatgaaaa atatttaata tcaggacgat ttttctgata
    27901 gcctttatta taacacaaaa gctcaaggca ggtaaaacga taaagaaatc aacttaaaac
    27961 tatgacacag tctcatctca tatgatatag ttattcaggt ttcctaatgg aaaacatatt
    28021 aacaacttaa taatggagag aagaaagttg aaaacaaaat catttagaaa ggtactgaca
    28081 acgtcagcta cctgtattgt gctggcaaca agctttgccg gaggaaccct aagagtctgg
    28141 gcagagcagc tttattatgg gtggaatgat ggaacgagac aaagttcgcc atattttttg
    28201 tacgtatcgc ctaaaaatgc tccaaagcgt gaattaaaag acgagtatgt tgtttattgc
    28261 tttaacaaaa aattgtattg gccagatcaa tgggaatcta tatacagcaa ttttaatgac
    28321 atcagatctc catataacga tttacctgta tatgagaaaa aactaggata tgatggtata
    28381 tttaaacaat atgctccaga ttacaaaaaa gatattagtg atatcgcaag tgctttggtg
    28441 gcagttttaa gtaatggata ccccactaac aagtcacaac tatcaactag ctaccattta
    28501 aataatgatt cttctagaaa agttactcaa ttagccattt ggtattttag tgatagttta
    28561 acaaaagaat accttaaaga tacgggtggt tataacttaa acgatatgga aaaaaaagct
    28621 ttagattttt taatcagtaa aggagaggat tctaagctta aatcagagca gagtaattac
    28681 tcattggata tttatgttta tcaaagtggc gggcatgacc atatgaaaga ttaccaaaat
    28741 cttctcggct ctaccttaat tcctaaagaa ccgctaaagc ctcagctagg tggttttagt
    28801 ggacataatg gaaatggatt aagcggcctt gaaggaggat catcaggttc acaagaaact
    28861 aatgaagatg gtaagaaagg acttataggt ttccatggag gactctcagg aagcgagggc
    28921 aaacgagatc ctttccagga ttgaagggtg aggctggtgc acctgataca cctcaaaagc
    28981 ctaatgaccc attgcaaagt cttgaaggtg gtaactctcc tatcgtagaa caaaactatg
    29041 gtagtactga gggatatcat ggtcaatctg gcattcttga ggaaaccgaa gacactaacc
    29101 cacctggtat cattttaggt ggctcaggaa atgtcgaaac gagatcctca tctgatgggg
    29161 cttggcggtg gtctagctgg cgaatcagga gaaacgacac ctaaaccagg acagactggt
    29221 ggtcatggac caatcatcga gacaacagag gacacacaaa aaggcatgtc tgggcaatct
    29281 ggcggcacta tcgagtcaga aaacaccaaa aagcctgagg tcatgattgg tgggcaggga
    29341 caaaccatcg aaacaacaga ggacacacaa aaaggcatgt ctgggcaatc tggcggtact
    29401 atcgagtcag aagacactaa aaaacctgag gtcatgattg gtgggcaggg acaaaccatc
    29461 gaaacaacag aggacacaca aaaaggcatg tctgggcaat ctggcggtac tatcgagtca
    29521 gaagacacta aaaaacctga ggtcatgatt ggcggtcagg gacaaatcat cgacttctct
    29581 gaaaacacgc aatcaggtat gtctggacag tctggagaca ctacggtcat tgaggatacc
    29641 aagaagtctg agataatcat tggtgggcaa ggacaaatca tcgacttctc tgaggatact
    29701 cagccgggta tgtctgggca atctggaggc accacaattg tcgaagacac caagaagccg
    29761 acacctaagc ctaaacctgc acctgcgcca attgttaatg acgaaaaacc taacaaaggc
    29821 actcagctcc cacagacaaa tgatatgaag caactcaccc taagcatcat cggtgcaatg
    29881 tcaatgctgc ttgtcctatg tctgtctcta ttcaagcgac catctaaaaa agactaagca
    29941 acactgacaa gtgatcatta ttgtacggac gtttacaggc gggctttctg ccctcttaaa
    30001 acaccgtaca acaacaaaac ggtctaaata gaaatatccc tcaagggtta gacaatcgct
    30061 ctagcccttg gggctttttt tgatacttat aatagaagag agcaagcagt gacactttct
    30121 ttttgcccta tatctgctaa cactagcggt atgtgcagtt accataggct atcaactcgt
    30181 cgtgcaactc tagagaaaag ctgatacaaa aaacaagcac cagccttgct gctgatgctt
    30241 gctccggact tactgataag cctttgtgat gtcctagctt tataaccata tgcctattac
    30301 ctaaaggtct agtctcctaa tggtgggctg gctggtaaaa gcaaggagaa acagctcccc
    30361 tttccaagct ggctctcaac agcaatatcc ccacctagtt ggcgagctaa ctgcctagca
    30421 atagagagcc ccagcccatg accaccagtc ttcatattgc gagaggcctc aacacgatac
    30481 aggcgcttga aaatcaaagg caggtcctct tttttgatcc cttgcccctg atcaataaca
    30541 tcaatgcgaa tggactgctc ctgttgataa gcatgaatcg tcaaagccgt attagccttt
    30601 gaatatttaa gcgcattgct gactaaattc agcataatcc gagacaaagc atcatatcgg
    30661 ctgctgatct taaccacctc ttttgccacc tcaatatgaa cggagcgttt ttcctgctct
    30721 aaggtcaatt gaaattcgga tagcatgtca atcaatagct tttcaagata gatgatttga
    30781 agctgctgct tgtcgtcttg cttttgatca tttaagctga ccatatgcaa ttcttcaact
    30841 aattgattca aacggttggt ctgtcgtgag atggtgttta gatagtgcct ttcctcttcc
    30901 cttggaataa cgccatctaa aatcccctct acagttgctt gaatagaggt caagggtgtc
    30961 ttaatatcgt gcgacagctg agcaatcatc atggatttct catgctcact ctcactcaat
    31021 gactcaaagc tgacctttag ctctgaggac atctgattaa aggcttcctc tagatcttta
    31081 aactccaaag gacacttgat gagctgacca ctatcaaagt ttctttcaga aatagcctgt
    31141 atctttttct ttagcctttt aagcgatgaa aaaacattac tcaaaaggat catattcaca
    31201 attcctccgg ctactgaagc aattagagct attactaaaa tatatgaaat atcctcaatg
    31261 gtaatgagca tttggtttaa cccaacaatc aggcctgcaa tagtaatcag catagacatt
    31321 aaatagccaa tgacaatgta cgttcttaat cgcatgctac ccctctaatt tataacctag
    31381 tccccaaacc gttttaatgg ttggtgtttg ctcggtactg tattttgcca agtcattgcg
    31441 tagggaatga atgtgaacat ttaaggtatt ggtatcatct aaatactcct cctccca
//
LOCUS       DARYLJ010000026        31301 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYLJ010000026 DARYLJ010000000
VERSION     DARYLJ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31301
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..165
                     /locus_tag="TU746_001063"
     CDS             <1..165
                     /locus_tag="TU746_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891413.1"
                     /translation="VTYDSLVGQTKRHFDDKVTQARGLATKFKTVKEQLEEGVERTAA
                     IDQKLGCDFS"
     gene            162..554
                     /locus_tag="TU746_001064"
     CDS             162..554
                     /locus_tag="TU746_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891414.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            574..858
                     /locus_tag="TU746_001065"
     CDS             574..858
                     /locus_tag="TU746_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891415.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     regulatory      1512..1637
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            1710..2288
                     /locus_tag="TU746_001066"
     CDS             1710..2288
                     /locus_tag="TU746_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0891416.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     gene            2278..2928
                     /locus_tag="TU746_001067"
     CDS             2278..2928
                     /locus_tag="TU746_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL0891417.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            3119..4042
                     /locus_tag="TU746_001068"
     CDS             3119..4042
                     /locus_tag="TU746_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL0891418.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            4055..4840
                     /locus_tag="TU746_001069"
     CDS             4055..4840
                     /locus_tag="TU746_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL0891419.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            4850..5407
                     /locus_tag="TU746_001070"
     CDS             4850..5407
                     /locus_tag="TU746_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0891420.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            5535..6869
                     /locus_tag="TU746_001071"
     CDS             5535..6869
                     /locus_tag="TU746_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL0891421.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            6946..7737
                     /gene="pflA"
                     /locus_tag="TU746_001072"
     CDS             6946..7737
                     /gene="pflA"
                     /locus_tag="TU746_001072"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL0891422.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            8237..9172
                     /locus_tag="TU746_001073"
     CDS             8237..9172
                     /locus_tag="TU746_001073"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL0891423.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            9239..9892
                     /locus_tag="TU746_001074"
     CDS             9239..9892
                     /locus_tag="TU746_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL0891424.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(9997..10995)
                     /locus_tag="TU746_001075"
     CDS             complement(9997..10995)
                     /locus_tag="TU746_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0891425.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILTACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(10992..12017)
                     /locus_tag="TU746_001076"
     CDS             complement(10992..12017)
                     /locus_tag="TU746_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0891426.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            complement(12027..12965)
                     /locus_tag="TU746_001077"
     CDS             complement(12027..12965)
                     /locus_tag="TU746_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL0891427.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            complement(12990..13769)
                     /locus_tag="TU746_001078"
     CDS             complement(12990..13769)
                     /locus_tag="TU746_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891428.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            complement(14029..15474)
                     /locus_tag="TU746_001079"
     CDS             complement(14029..15474)
                     /locus_tag="TU746_001079"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL0891429.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            15560..17191
                     /locus_tag="TU746_001080"
     CDS             15560..17191
                     /locus_tag="TU746_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL0891430.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAA
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            17341..17970
                     /gene="upp"
                     /locus_tag="TU746_001081"
     CDS             17341..17970
                     /gene="upp"
                     /locus_tag="TU746_001081"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL0891431.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            18201..18791
                     /locus_tag="TU746_001082"
     CDS             18201..18791
                     /locus_tag="TU746_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL0891432.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            18896..19342
                     /locus_tag="TU746_001083"
     CDS             18896..19342
                     /locus_tag="TU746_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL0891433.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            19343..19627
                     /locus_tag="TU746_001084"
     CDS             19343..19627
                     /locus_tag="TU746_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL0891434.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            19943..20578
                     /locus_tag="TU746_001085"
     CDS             19943..20578
                     /locus_tag="TU746_001085"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL0891435.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            20592..21467
                     /locus_tag="TU746_001086"
     CDS             20592..21467
                     /locus_tag="TU746_001086"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL0891436.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            21464..22264
                     /locus_tag="TU746_001087"
     CDS             21464..22264
                     /locus_tag="TU746_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL0891437.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            22257..22580
                     /gene="yabA"
                     /locus_tag="TU746_001088"
     CDS             22257..22580
                     /gene="yabA"
                     /locus_tag="TU746_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL0891438.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            22585..23451
                     /gene="rsmI"
                     /locus_tag="TU746_001089"
     CDS             22585..23451
                     /gene="rsmI"
                     /locus_tag="TU746_001089"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL0891439.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            23957..24112
                     /locus_tag="TU746_001090"
     CDS             23957..24112
                     /locus_tag="TU746_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0891440.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            24171..24371
                     /locus_tag="TU746_001091"
     CDS             24171..24371
                     /locus_tag="TU746_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL0891441.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            25039..25632
                     /locus_tag="TU746_001092"
     CDS             25039..25632
                     /locus_tag="TU746_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL0891442.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            25972..27477
                     /gene="glpK"
                     /locus_tag="TU746_001093"
     CDS             25972..27477
                     /gene="glpK"
                     /locus_tag="TU746_001093"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL0891443.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            27651..28295
                     /gene="fsa"
                     /locus_tag="TU746_001094"
     CDS             27651..28295
                     /gene="fsa"
                     /locus_tag="TU746_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL0891444.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGGHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            28679..30667
                     /gene="tkt"
                     /locus_tag="TU746_001095"
     CDS             28679..30667
                     /gene="tkt"
                     /locus_tag="TU746_001095"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL0891445.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(30849..>31301)
                     /locus_tag="TU746_001096"
     CDS             complement(30849..>31301)
                     /locus_tag="TU746_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0891446.1"
                     /translation="QGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKG
                     EQGQRGENGEQQPKGDQGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSAS
                     PKAPAPQSTPSKKAVLPATGEASHPFFSLAALSVIASAGLLTLKRKKS"
BASE COUNT         8626 a         6148 c         7568 g         8959 t
ORIGIN      
        1 gtgacctatg acagccttgt gggtcagacc aagaggcatt ttgatgacaa ggttactcaa
       61 gctagaggac tggccacaaa gttcaagacc gtaaaggagc agctagagga gggggttgag
      121 agaacagctg ctattgatca aaagctagga tgcgactttt catgacagca ttagaaaaga
      181 tcagaactgc tatccgtcaa aaggaagagg agctagagga gcagcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctac
      301 agcagctcta tgcctctagc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gtctgataac agaccaatat accgttctaa cgaggctgat tgatgactac cagcaccgaa
      421 cagagcagtg ctatcatgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggcgatag aaaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga aagatgattg ctatagagat gatcttaacc
      601 ggacaagagc cgatcaggac tttaaagaaa gagctggata ggagattagt tcagtccata
      661 tgtgctccct tgaccttagg tcgccttcat gcccttcaaa ggcgctatga cagtgaggta
      721 tctcggattg ccacagacac cgcagatcat attcagacca ttgtcaatca gctagatagc
      781 agcattagag ggcaaggcag gacagcacta gagcaggcga tcaagacaca gaacaggggc
      841 tatagcagcc tgatgtgaga caagaaggac ttactgtcct accagctaca gtcactacac
      901 tgctagagct tgcggtgtga gcagcagtaa gaagcaaagg cgctgcccta gagggctgat
      961 gaatcaccat caccagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt cagaatgtag gcaaacccta tcagcgatag aaaaattgaa
     1081 catttagaaa ttgactatca tatcatgaaa actctgggaa atgctgatat tacagtattt
     1141 ttcagacttc ttttgttttt ttgattaaaa gaaaaagatt gaagaaaacc gtctaaaatg
     1201 gactttttct tcaatctgaa aactctgatt ggagttttca ttggttaggt gtgtctatga
     1261 ccgtaaaggg gacaacggta gtaataccag agcaggttat tggaggtttc ttctagtctg
     1321 ctcttttttg ccttgagcta ggctagtgcc atgtcacagg gtggcctacc tcgtagagag
     1381 ctttgtagcc tcaaagtgat ttttcttgct gttgctttca tctagctttt ttgcctgatg
     1441 tcttgtgttt gttggaaaag ctaggcttca aaaaaatgtc ttgcgctata ggtttaaatt
     1501 tgctatgcta taagtgtctt cagggcaggg tgtaattccc gaccggcggt gactagtgca
     1561 gctagaagtc cgcgagcgca agctgatgtg gtgtgattcc acaaccgaca gtaaagtctg
     1621 gaagagagaa gaccgggttt ttgagttgac tttttgcctg ctcatacgaa ggagcttctt
     1681 tcaatttgtc aaaattggag gaatttttta tgtcaaaaac acatcaactg gtgatggttg
     1741 ccattctttc agccatatcc ttttgcctga tgtttgtggg gttttccatt attccaggag
     1801 ccagcttttt aaagattgat tttagtatca ttccgatttt gttaggcttg gtcttgatgg
     1861 atctaaagca agctaacttg attttagcgg tgaggacctt gcttagacta gccttaaaca
     1921 atcatggcgt taatgatttg attggtatac cgatgaatgt tatagcagtt gcgcttttta
     1981 tcactgcctt tgccttgatt tggcatcgtc agaaagggct ggtcacctat gtactagcta
     2041 gtcttgtggg gacagggctg ttaacgcttg gtatggttgt catgaactat gtctttgcta
     2101 ttcccttata tgccaagttt gctggctttg atattaaagc ttttattggt actgctcgct
     2161 acatatttac aatggtcatt cctttcaacc ttttggaggg gctaatattt gcaattgtct
     2221 tttatttcgt gtatattgca ggtaaaccaa ttttagagag atatccgaat tcatatcatg
     2281 aaacataaac aacaacatct gctattgtct tcctttgcta tgctactatt tgtggtgctt
     2341 ggctatattg ttaaattttt tcccgaagac ctaacgtctt ttgatagtca gcttcggtta
     2401 gccctaagag gtcatctgcc tgaagggcta acccagtttt ttaaagggat cactgtagct
     2461 ggaaatgtta gtacacaggc agtgattgtt gttgttgctg tgctggcttt attggccttg
     2521 agctggagag ctgaggcctt atttgtccta tcaaatggtg tttttgcggc ccttttgatt
     2581 tgggtgctaa agctcttgta tcaaagacca agacccagca ttgagcattt ggtgcatgct
     2641 tctggctatt cttttccgag tggccattcg atgggaagcc ttttgattat tggaagtctg
     2701 ctgattattt gccatcaaag attgcagtca gcctccttac gctggctggt tgatatagcc
     2761 cttttggcct tgattttgct gataggcttg tcacgcattt atctgggagt gcattatcct
     2821 agcgatgtgt tggctggcta tgccttaggc tttggcatac ttcagctgct ttatcctttt
     2881 tatgatcaaa agcgctttga atggcgtttt cagctaaagc aaaagtaaat ccagtgatca
     2941 gtcagctgta tggcgcgtta cagatcagtt ctagaaaagc tagtgattga aggcaggtct
     3001 cttccagagg tcttcttcaa tcctttttag ttgccttgct ttggctcatc aatcagagaa
     3061 gtagcagcca attgagatct tctgctgtta atcgggggat ttgtgctaca atagaggcat
     3121 gacaaaaaga tatcagacct taaatgagta ttatcgtcgt ttatttggtg ctaaaatttt
     3181 caaggtgccc attgatgctg gctttgactg tcctaatcgt gatgggacag ttgctcatgg
     3241 tggctgcacc ttttgtaccg tttctggctc aggtgatgcg attgtggcgc ctgatgcacc
     3301 tatcagggaa caattttaca aagaaattga ttttatgcat cgcaagtggc ctgaggtcaa
     3361 tcagtatttg gtttattttc aaaattttac caatacgcat gataagctag aggttattcg
     3421 cgagcgctat gagcaagcaa tcaatgagcc tggcgttgtt ggtatcaata tcggaacaag
     3481 gcctgattgt ttgccagatg agacgattgc ttatttggct gagctatcag agcgcatgca
     3541 tgtgacagtg gagcttgggc tgcaaacaac ttatgaagcc acctcccagc tgattaatcg
     3601 ggcgcattct tatgacttgt ataaggaaac ggttcagcgt ctgaggcagt accctaacat
     3661 taacattgtg tctcacttga ttaatggctt gcctggtgaa acccatgaga tgatgatcga
     3721 aaacgttaga cgctgtgtca cagacaatga tattcaaggc attaagctgc atttgctgca
     3781 cctgatgacc aatacgcgta tgcaaagaga ctatcatgag ggacgcttgc agctcttgag
     3841 tcagaaggac tatgtatcga ttatctgtga tcagctagaa atcatacctg agcatatcat
     3901 tattcatcgc atcacaggtg atgcgcctag ggacatgctg attggtccca tgtggagcct
     3961 gaataaatgg gaggttttga atgcgattga cctagaaatg gaaagaagaa atagctggca
     4021 gggctgtaag cttaagggat aatcggggga agcaatgaaa caaagattga tagcaggaga
     4081 ggagctgagc ctaccacctg ttttaaaaaa actgttacaa aacagtttgg tttatgatag
     4141 cagtagctcg gcagaggcac gtgtttatgc tattgataaa gggcagggct attttctaaa
     4201 aacagccgct aaaggtaggc ttgccaagga ggccgcccta actcggtatt gtcatagtaa
     4261 gggcttagca acagaggtgc ttgattatat cagcggtgat caggattggc ttttaaccgc
     4321 aaaggtagca ggagaggacg ccagtcatat tgaatatttg tccgatccca agcgcttatg
     4381 tcgtatctta gttgatcata tgctaaagct gcatagcctg tctttgtctg attttcctgt
     4441 agctgacaaa acgctagcct atatcgaagc tgctgaggct ggttatcacc aagggcggtt
     4501 caatcagtgc tttttaccgc ctcagcaacg gtttcagtcc caggaggagg cttacaggcg
     4561 gattcaggag cttaagctct tgttacagca tgaaactctg attcatgggg atttttgttt
     4621 gccaaatatg atcttggatc ggtggcaatt tcagtccatg attgattggg gggaggcagg
     4681 aaaaagcgat cgacatattg atcttttttg gctgatctgg tcgcttcaat tcaatctaaa
     4741 aacagatcgg tataaagatt atgtgctaga ttgttacggc cgaaggcata ttgacttaga
     4801 catactagat ggtatcgcgg catttgaagt atttgcttag gaggataaga tgataaagcg
     4861 tcctattcat gtatcacatg aatttttaaa agaagttttg gataagcaga gtattgctgt
     4921 tgatgctact atgggaaatg gctatgacac tgccttttta gcaagtctgt cacaaagggt
     4981 ttatgctttt gatgtgcagc agcaggcact gaccaagaca caagagcgct tggagcagca
     5041 aggcttgact aatgcagagc ttattttagc tggacacgag caggtggatc aatatgttaa
     5101 ggagcccatt cgggcagcca tttttaatct gggctatcta cccaatgcag ataagtcgtt
     5161 gatcacaagg cctgagacga ccatattagc cctagctaaa atacttgatc ggcttgagct
     5221 aggtggacgg attgctatca tggtgtatta tggtcatgat ggcggtagta gggagaagga
     5281 agagcttttg gactatattg gtcagctcaa tcagcgccag gtaacagcaa tgctctatca
     5341 gccgatcaat cagatgaatc agccgccatt tttaatcatg ctggaaaaaa tagcagctac
     5401 tgattaagct tcagccagcc ttatgtcagg gcttagactg tctgtgattt ctcaggaaaa
     5461 agaaataaat cagcaatctt tggcgacaat tgtgatataa tgaagtagta tattatgttt
     5521 taggagttat attaatggaa gaccctgtga gtcagccttt attgattcag tttttattgt
     5581 tagtcattct aaccttgtta aatgcctttt tctcagccag tgagatggct ctggtatcct
     5641 taaatcgctc tcgtgtggag caaaaggctg ccgatgggga taagaggtat gatcgcttgc
     5701 tgcgtgtttt agagcagccc aataactttt tatcgaccat tcaggttggt attaccttta
     5761 ttagcctctt gtcaggggcg agcctgtcag cctctttagg gcaggttatt tctggctggt
     5821 taggtggttc tgcgaccgct caaacagctg gtagcattat ttctttggtg ttcttgacct
     5881 atgtctcgat tgttttggga gagttatacc ccaagcggat agctatgaat ctaaaagaca
     5941 agcttgctgt gatttctgcc ccagtgatca ttatcttggg gaaattggtt agtccctttg
     6001 tttggctctt atcggcgtcg acaaatttac tgagccggat taccccaatg acctttgatg
     6061 acgcagatga gcgcatgacg cgtgatgaga ttgagtacat gctgactaac agcgaggcaa
     6121 cgcttgatgc cgaagagatt gaaatgctgc aggggatttt ctcgcttgat gagatgatgg
     6181 cgcgtgaggt gatggttcca aggacagatg ccttcatgat tgacattaac gatgatacgc
     6241 tagacaatat caaggaaatc ctaaagcaga gcttctctcg tattccagtt tatgatgttg
     6301 acaaggacaa ggtgatcggc ttaattcata ccaaaaggct tttagaatca ggctttcgtc
     6361 agggctttga aaacatcagc atgagaaagc ttctgcagga gccgctcttt gtaccagaaa
     6421 cgatttttgt agatgatttg ttgaggcaat tgcgaaatac tcaaaaccag atggctatcc
     6481 tacttgatga gtacggaggg gttgcaggtt tggtgacgct tgaggatttg cttgaggaaa
     6541 tcgttggtga gattgatgat gagacagaca aggctgagca atttgttcat cacattgatg
     6601 acaacaccta tattgtcaca gggacaatga cgctcaacga ctttaacgag tattttgaca
     6661 cagaattaga aagtgatgat gtcgatacca tcgcgggctt ttatttgaca gggattggta
     6721 ccattccaag tcaaaaggag aaagagagct ttgcctgtga tagcaagcaa aagcatctgg
     6781 ttttggtcaa tgacaaagta aaggacggtc gtatcaccaa attgaaactt actatttcta
     6841 atatagaaca gaatattact gaagactagg cattgagctt agtctttttg atgaaacatg
     6901 atataatgaa aacgtaaaac catttacaag ggtgaaggag acacaatggt tgaagtagat
     6961 tatgggcaag taactggaat ggtgcattct acagaaagct ttggttctgt tgatggtccg
     7021 gggatacgtt ttatcatttt tttgcagggc tgcaagatgc gttgccagta ttgccataat
     7081 ccggacacct gggctatgga aaccaatcaa tctcaacgcc gaaccgttaa tgatgtccta
     7141 aaggaggctc tgcaatatag gcacttttgg gggaaaaagg gtggaatcac tgtgtcaggt
     7201 ggtgaggcta tgctgcaaat ggactttatc actgcgctct ttactgaggc caaaaagcta
     7261 ggtatccata caacgctaga tacctgtggc tttgcctatc gtccaacccc tgaataccat
     7321 gagctgttag aaacattatt agcagttact gatttgattt tgctggactt aaaggagatt
     7381 gacgaggagc agcataagct tgtcacccgt cagcccaata aaaatatcct gcagtttgct
     7441 cgctacctct ctgataggca ggtgcccgtc tggattcgcc atgtcttggt gcctggcttg
     7501 acagacattg atgatcactt ggtacgctta gatgcgtttg tcaagacctt gagaaatgtc
     7561 gacaagtttg aggtactccc ttatcatacg atgggagagt tcaaatggcg cgagttaggg
     7621 attccatacc agcttgaggg cgttaagcca ccaaccaagg agcgggtgga gaatgccaaa
     7681 aagctgctgc atacagaatc ctatactgaa tacatgaacc gtattcatca atcataggct
     7741 aagctagagt tgggaaatgc ccagcttttt ttggccccat gtcaactgta gtgggtgact
     7801 gataactaag cacgagacga agctcgtttt ctcttgtgtg atgtgcaaag cgaggtaaat
     7861 gggctctata atttctgtag tgggtaaatc caccatggaa attatagagc cgtttttttg
     7921 ctgatgaagc ggctggcttg atgagacctt cagtgttttt aagcgagctc agacacgtgc
     7981 caaaaagtaa tccttgaagc attaaaccaa tcaaggacag tgtattgtcc ccaaatagct
     8041 gaatagctca ttatagaagg cattgctttt tggactggct tgcctgttct tgtgtgtttg
     8101 acaggactct ttaatacctg agattctgtg cccttatgcc ctttagactc ttggcctgtg
     8161 actggggaat cttctttgat tttagagcct atttctgcta caataagatg aataaagaga
     8221 atgaggtaga aactttatgt caaaactatt agtttttggt catcaaaatc cagatactga
     8281 tgccatcgca tcatcgtatg cttttgacta cttagcaaaa aaagcctttg atttggatac
     8341 ggaggtagtc gctctgggtg acccaaatga agaaacagcc tttgcccttg actattttgg
     8401 ggtatcagca ccaagagtgg tgacatcagc aaaagcagag ggtgctagtc atgttattct
     8461 aacagaccat aacgaatttc cacagtctat ttcggatatt cgtgaggttg aggtgtatgg
     8521 tattgttgac caccatcggg tggctaattt tgagacagca aatccgcttt atatgcgtgt
     8581 cgaacctgtt ggctctgcct catctattgt ttaccgcctg ttcaaggaaa atagggttga
     8641 tgtgccaaag gacattgcag gcatgctttt gtctggcttg atttctgata ccttgctgtt
     8701 aaaatcacca acaacgcatg cttcagatca tcgtgttgct gcggaattag cagagttagc
     8761 aggagttaag ctagaggaat acggtatggc tatgctaaag gccggaacaa accttgcaag
     8821 taaatcagaa gcagaattga ttgatattga tgctaagacc tttgaattaa atggcaacgc
     8881 agttcgtgta gcccaggtca ataccgttga cattgcagag gtgttagagc gcaaggaggc
     8941 tattgaggcc gctattagag aggtgatggc aagtgagggc tattctgatt ttgtcttgat
     9001 gattacagat attgttaatt caaattcaga gattttggcg cttggtgcga atatggataa
     9061 ggttgaggca gcctttagct ttaagcttga ggataatcat gctttcctag caggtgctgt
     9121 atctcgtaaa aagcaggttg tccctcaatt aactgaaagc tttggagcat agagcttgcc
     9181 tgtagagggg tgttgatttt tatcagcagc cctttggtct ttttgctata atagtagtat
     9241 gattaccatt tttaaccctg ataaattaac gcgtcagcct ttttttcaag accttattca
     9301 ttacctcaat cagcatgatg acgtaaccct gcgtcacatt aagcaggcct tttctcatgt
     9361 taaggggatt gataaggcgc ttgaagctta cattcaggct ggctatatct gtcgaaaaaa
     9421 cagacgctac tatctgtgtc tgcccttgct agatgacctg cagcaggtga cattagaaga
     9481 tctaatcttt gtggataggg catcagatct atatgaagct ttgatggcct tggtgtttga
     9541 gacagtgctg tctaatcaga ccaatcaggt tttgatcaag gaaaaaacaa ccattgaccg
     9601 agataagctg acgcttgcca attattttta ccgcttaaga agaggggaag ccctatctga
     9661 tgagcaatta aggctctatg ccctattagg tgatgtgaat caggactatg ccttgaagta
     9721 catgaccagc tttcttctaa aatttgctag aaaagagatt gttatgcaaa agcggacaga
     9781 tatttttgtg aatgccttgg agcttctagg ctatattgaa aaagtagagg ccactaaata
     9841 ctgcctgaag ctggcttttg ataaggagca gctgattttc tacgctgatt aagagttgac
     9901 ttgatgaata aaaaatggct tagacccaca ctgtaaaaca gttgagtcta agccatttat
     9961 gcttgctgag ccctttaagc tatgcagcag aggctcttat gtcattttga ccatcagata
    10021 gagaaaatag gatgcaccaa taattgagac aagaataccg gttggtatat tgctgccgac
    10081 gagatagact cgtccgatag tgtcagccaa gagaagcaga atcatgccga tgaaaaggct
    10141 gacaggcagg cttaatcggt gatcagctcc cactagtcgt ttgctggtat ggcctgctat
    10201 cagaccaata aaggtgatgt ttccgaccaa aataacactt agggctgaga gaatcgcaga
    10261 tagtgcaaga acaatggtac ggtactgatg gagcttgaag cctagagcca tgcttgcttc
    10321 atcatttaat gccatgatgt tgagcttata ggcttgacta aaggctagca gccaagtgat
    10381 ccccaataag ggagcaacaa tgcttagctt ggaccaatca tcgcctgtta gctgcccgct
    10441 tagccaatga atcacataat ccaccttata acggttcaca ttgccgacaa aggcaatcat
    10501 caggctagat agcatggttg atagccctac gccagtgaca atcagccgaa taggatcaat
    10561 atggccatga cgaagtgaga gcaggtagac caagacaatg gttgccattg ccccggatat
    10621 ggtcataagc ggcagccctt gcctgctggt cagactgtta ctagtgctgt aggatatgac
    10681 aagggtaata gccataccag caccagcatt aatgcctagt atgccagaat ctgccagatg
    10741 atttcgcgtt aagctttgca gcattaagcc agaaagggcc agtgagccgc caccgataca
    10801 ggcagttaaa attcttggga gtctaatgtt ggtgatgatc aaggccatat cagcagtgga
    10861 tttaccaaaa agcaccctga cgacctccaa tggtgacatg ctagattccc caatagacaa
    10921 ggaaataatc atcaaacaga ccagtccaga gattagtcct agaaataatg ggacgtgtct
    10981 tttagtagct gtcaaaagcg acctcctttt ctaactagcc ataaaaagca gggcagccca
    11041 ataaagctga tcaaagcaga tagcggtgtt tcataggggg gattgatatt ccgacaggca
    11101 aagtctaccc aaagcataaa gctggctcca agaagagtag ctagcggcag gatccagcgg
    11161 taatccttag cagtgactaa tgtgatggca tgagggataa tcaagccgac aaaggaaatg
    11221 ctgccggcta ctgctacagc agcagaagac agaagcagca caagtccaat aaagataagg
    11281 ctaatcaaga aggtgcgttg ccctagggcc ttggcctgct cttgacttaa gcttaaaatg
    11341 gtcaaatgat aggctagcag ataagatagg gctaagccac agatgatgag tggcgcaaca
    11401 tagctaacca tctgccaatt gaccccgatc aatcctcccg cctgccagcc aataatggca
    11461 ttggctaggt gacaataagt tgttattcct tgtccgatag ctgacagtag catagatatc
    11521 atcgctcctg ctaaaataag cctcatttga gtgtagccct taccagcttg ataggctagg
    11581 ctgagaatta atagggtcgc taagagtgac cctagcaagg aaagtaatat aattgtcgaa
    11641 taatgaagat gaggggaaaa agcatagccg atgactaatg ccagcccagc tccagagttg
    11701 attcccagta agccaggctc ggcaatggga tttctggtaa tgccttgcat gatagctcct
    11761 gaaacagcaa gtgcagcacc aactagagct gctaaaatca agcggggcag gcgaatgtcc
    11821 aaaataatgc tggccttttg accctggtcc tgctttccaa gtagaatatg atagagctcc
    11881 tgatgtgata gtgacacagc cccaaacctc agactgcagt aaatggcaag cactagagtt
    11941 aagctgataa aggttaagat cagccaagga ggagctgctt tagctagttt aggcttagta
    12001 tgatgttgag ctgtcatctt aagtttttat tgacttgcac cagttgagag gatagccttt
    12061 tttagaacct caagctggtg ctccagtgac agtgggtctg tgaagtaaaa gacattagcg
    12121 ttgaccttga tgacatgatt gttggtcaca gcagggatct gctgccaaag gtcgctctca
    12181 tataaggctg agccggtttg gtcatcctca gcagcaacaa tcacataatc accaatataa
    12241 tctggtagaa cctcctgtga taaggacaga tagccctgct taaacacctc ttttttcacc
    12301 ttttcgggag catcataatg taaggcctga tgaataattt caccacctct tccccagtcc
    12361 ttaccaaaaa ggtaaatttc cttttcatag agccccatga ttgtaaaggt agcagctgat
    12421 ccggtgactt gttttatttc tttttcatag tcacttgttt tttgtttcca gtcggccaac
    12481 cattggtcag tttccttttc cttgttaaaa atacggccaa aatcagaaaa cacctgcaaa
    12541 taatcacgct tgcggtattc aatggagatt agtggtgcga tttttgctag ctggtcaatg
    12601 ttttcttctg ttgagccaac aacaatgaga tcaggctcta gtgctgtaat agcctctagg
    12661 tcagtagctg ccacctgctt ggcttgagta atgctttttg ttaaaacagg gttctttttg
    12721 tcgtaggagg tgacaccgac cagatgaagg tctaattttg ccaagtaacc agtatatgta
    12781 gctgctaagc taaccacgcg ctttggcttg acaggaatgt caccataata ggtcactcca
    12841 gcaatttttg gcttgtggga taggcttgct ttgctggtgc tttcttgttg cttgctttga
    12901 cttgagcagg cgactaatgt aaaagctgtc acaaaaacag ttaaaataag cagtagtttt
    12961 ttcatgtatt ctattctcct agaataaatt tatatcagct gataggtcag caatgtaggg
    13021 caatgataga gaggatcagt gacgagctga gcctttactt gaaaaatgtc ttgaatcatc
    13081 tctggcgtca tcacctggtt gacctctcca gaatatttga tatgtccatt tttcatggcg
    13141 atcagatgat ccgagtagcg tgctgaaaga tttaaatcat gaaggaccat cacgattgtt
    13201 tttccagaga cctgattgag ctcctttagt aattctaaaa tatcgagctg atgattcata
    13261 tctaagtagg ttgttggctc atctagaaaa ataatatcag tatcctgtgc taaggccata
    13321 gcaatccagg ccctttgacg ttggccgcct gacagggcat caacagcctg atgagcatag
    13381 ggtgccatgc ttgtgacctc cattgcccag caaatcttat ccttatcagc ttgactgagt
    13441 tgtcctaggt aggattggtg gggataacgc ccataagaaa ccagctcata gacagtagct
    13501 gtagtagctt cttgcagctg aggtaaaact gctagtgttc tggcaacgtc cttggttgct
    13561 agtctagcaa tggcttgtcc atctaagaga acctgccctg ctttgagtgg caatagtcgt
    13621 gccagagtct ttaaaagggt tgacttccca cagccattag caccgatgat ggttgttacc
    13681 tttccttcgg gaatagtgac agataagttg ctgatgataa gcgattgatc atagccagct
    13741 gaaatcctct cagcactgat tgttgacatg gtttttctcc tttctaatag tcaagcaaag
    13801 ccagctagca aaattctaag gggctgatag cctatgaaat gctagtcgct tttttggtct
    13861 gactataata gtgcgctttc tcttaaaagc tatcccatta tagcatagaa aaaaggccta
    13921 aaaaagcctt tcagaatcta attactgagt ttatgctaaa aaaggagcca gcttagaatc
    13981 attatcagta atcttaagaa ttattactgt ttagcctgtt agaccagtct ataggtagct
    14041 ctttgcaatc gctaaatcac ctgcataggc agtcttttgt cccttgacaa tctgataagc
    14101 atcagccccc ttgccagcaa taatgagtgc atcctgctca ttctgacagc gctccatacc
    14161 agtcttgatt gcttctttac ggtcaatgat aatatcaacc tcgcggtgaa tatagctagc
    14221 aatctcctct gaaatcagct gtgggtcctc aaaattagga tcatcagcag tcagaataat
    14281 acgaacattg gggtgctggt tgatgacttg cccaaaatca gcccgacggc tctcgccttt
    14341 attgcccggt gctcctagaa tcaagtaaat ctggcctttc tggtactctt cgacaacaga
    14401 taggagcttt tcaaggctat caccgttatg tgcataatca acaaatacct tggcctgatt
    14461 ggtcatggtt aagacctcca tgcggccagg gacgtttgtc ttagcaatgc cttggcggat
    14521 atcctctagg cttgccccca gtcgaagaca ggctagtcca gcagccatag cattttcttg
    14581 attgaagctg ccaattaatt gaatcgcata gtctccagct accttgccgg ctgcttgaaa
    14641 tgagaaggcc tgccgctgca gcagcctatt gcaagcccct ttgccataaa aatcatgagg
    14701 cttatcagcc acctgctctg ctaggatatt aaaatgctcc ataccgctat tgaccacaac
    14761 agctcggcta ttttccatta agagccgctt atggtaaaaa taatcctcaa agcttgggtg
    14821 ctcgattggt ccgatgtgat cggggctaat attaagaaag acaccgacat caaaggttaa
    14881 gccgtagata cgcccgacca agtaggcttg actagagacc tccatcacca aatgcgtcat
    14941 gccattagcc acacactgag ccatcatcgc aaataaatca agactttcag gtgtggttaa
    15001 ctgcgattta aaaaagtgtt ggccatctaa ggtcgtgttc attgtagaga gcagggcagg
    15061 cttatgagat tcctttagca tatgataggc aaagtaggca gcagttgtct tgccctttgt
    15121 tccggtgaag gctaatagct tgagcttatt ttgtgggtaa tcataaaagg ccatcgcagc
    15181 taggctcata gcgtgcttaa tattgttaac aagaataaca gggatcccta cctgatagtc
    15241 aatctctgaa acatagagtc ttagtccctt ggcaatggcc tgtctcaaaa agtcagcctt
    15301 aaaagctgat cccttagcaa aaaagagcgt ctgctcatct gcttgtctgc tgtcgtagct
    15361 aaggctgtca aactgtagac cgctatagtt aaagtggtag ccgtcttgat caagaacctc
    15421 tcggaaatta tggtcctttt ttaaaatggt taataagtgc tcaattgtta tcatagcctt
    15481 attttatcct taatgttctt gttttacaag tcacaagcaa aagtttataa taaagctata
    15541 aaaactagga agaacggata tgtcgacaga aaaaaaacaa ttgacacaag aacagctgat
    15601 ggttcaggga gcagcctggt ccaccgcagg taattttatt agccgacttt taggcgttct
    15661 atatattatt ccatggtaca tatggatggg gcagtatgcg atacaggcaa atgcgctctt
    15721 taatatggga tacaatgtgt atgcctattt tttgttgatt tcgacaacag ggctaaatgt
    15781 tgccattgct aagcaggtcg ctaagtacaa ctcgatggga cagcaagagc atagctatca
    15841 gctcattcga agcactctaa aggttatgct ggtattaggc ttgattttct cagtgctgat
    15901 gtatctggga tctccgctct ttgctcgctt gtccggtggt gatgagaccc ttgtcccgat
    15961 tatgcatagc ttatcattag ctgtttttgt ttttccagtg atgagcgtga ttagggggat
    16021 ttttcagggc tataaggaga ttaagcccta tgctcttagc caaattgctg agcagctggt
    16081 tcgtgtgatc tggatgcttc taacaacctt tttcatcatg aaaatggggt ctaaggacta
    16141 tattgcagct gttacgcagt ccacctttgc tgcttttatt ggaatgatag ccagtatggc
    16201 ggtgctcttt tattatttct ggacgcaggg ccttttaaag gctattttta ccaagacaga
    16261 gcatgcgatt cctattgaca tcaagggctt gcttattgaa acgttaaagg agtcgattcc
    16321 ctttattatt acaggaagtg cgattcaggc ctttcagctc cttgatcagt ggacctttgt
    16381 caatacgatg actctgttta ccagctacac gcgttctcag ctctgggtgc tgtttgggta
    16441 ttttaacgcc aaccctgcta aaatcaccat ggtgctcatt gcagtagccg cttcaattgg
    16501 tagtgttggt attgccttat tgacagaaaa ttacattaaa aaggacatgc gagcagcagc
    16561 gcgcctgatc attaacaaca ttgaaatgct gctgatgttt ttattgcctg ctctgacagg
    16621 agctattata ctggcaaggc ctctttatac ggttttttac ggtagtagcg agggacaggc
    16681 tgttaggctg tttgttgctg tgctttgcct taccctattg atggccttgt atacgctttt
    16741 ttctccgatg ctgcaggccc tgtttgaaaa ccgtaaggcc atctattatt ttgcttatgg
    16801 tgtttttgtc aagctggttt tgcaggttcc tttgatctat ctgtttcatg cttatggtcc
    16861 tttgttagct acgacccttg gcttgctagt gcctatctat ctcatgtacc gtcgtctaca
    16921 tcaggtcaca cgatttaacc gtaagctgct gcataagcgt atattactaa cggtgattga
    16981 gacagcattg atgggcctga ttgtgctact agctaactgg tttttgggct atttgtttaa
    17041 gccgacaggc agattgacta gcctgcttta cttagtgatt attggtggct tgggaatggg
    17101 tgtttacgcc tacatgacgt tattgacgcg tcagctggac aaattaattg gcagcagagc
    17161 agctaggtat cgccaaaaat tgggactttg acacccaaga tcaaggcagc tgaagcaggc
    17221 agctagctga tcagattctt gcttttatca tttcaaccgg atctgaaaaa agtaagcaag
    17281 gttttcaatt ttttggtata atagcaaaag tgtaaaaaat aaagaaggaa gtacgtcatc
    17341 atgggaaaat gtcaggttat ttcgcatcca cttattcagc ataagctatc aatcctgcgt
    17401 cgtcaggata cctcaaccaa ggattttaga gagctggtca atgaaattgc aatgcttatg
    17461 ggctacgagg tttctcgtga cttgccatta gaggatgttg agattcaaac accggttgcc
    17521 aagacggttc aaaagcagtt agcaggtaaa aaattagcaa ttgttccgat tcttagagct
    17581 ggtattggta tggtggatgg ctttcttagt cttgtgccag ctgccaaggt tggtcacatc
    17641 ggtatgtatc gtaacgagga gaccttggag ccggttgaat atttggtgaa gctgccagag
    17701 gatattgatc agcgccaaat ttttattgtt gatccgatgc tggctactgg cggctctgct
    17761 attcttgcag tggattcact gaaaaagcgt ggggctgcta atattaagtt tgtgtgtctg
    17821 gtagcagcac cagaaggggt taaaaagctt caggaggctc acccagatgt tgacatttat
    17881 accgcagccc ttgatgaaag attaaatgat catggctaca ttgttcctgg tcttggagat
    17941 gctggtgatc gcttatttgg taccaagtaa aaggctacag gctttggttg tgctaggctc
    18001 tgcttgctag aggctagcct gctaaagcta ataagacttt ctagtttagg ctggaaggtt
    18061 tttaaaagca agtttatcat ttgacctttt ttgaccaaga gattataata aggtcaatca
    18121 ttataaaaag atgtgtttga ctgcctgtca ctgcatgagg cagagtggtg ttagacagtc
    18181 acgatagatt ggagattttt atgattcctg tagttattga acaaaccagt cgtggagagc
    18241 gttcttatga catttattca cgtctgttaa aggaccgtat tatcatgctg actggtccag
    18301 tagaggataa tatggcaaac tctgttattg cgcagctctt gtttttagat gcccaagaca
    18361 acacaaaaga tatttacctc tatgtgaata ccccaggagg ctctgtatca gctggtttag
    18421 ctattgttga tacgatgaac tttattaagg cagatgtgca aaccattgtt atgggtatgg
    18481 ctgcttctat gggaaccgtt attgcttcat caggtgcaaa gggcaagcgc tttatgcttc
    18541 caaatgcaga atatatgatt caccagccta tgggaggcac aggaggtggt acgcagcaga
    18601 cggatatggc cattgctgct gagcatttat taaagacacg tcaccgcctg gaaaagattt
    18661 tggcacaaaa tgccggtaaa acgatcaaac aaatccataa ggacgctgag cgtgattatt
    18721 ggatgagcgc agaagaaacc ctagcctatg gctttattga tgaaatcatg gaaaataatg
    18781 agctagctta gagagcttag taaaatagct taacagcttc tgaaacaaat tgtttcaggg
    18841 gctttttgca tgctaaagag ggctatcttc cttaaaatta tggtataatt aacctatgct
    18901 aatcataaat gaagaattgt ttgccattga aaaggctatt gagcagctgg ttcaggatat
    18961 taggacaagc agccagtatc aggcctatgc cttggctaaa aaggcttttg aggcagattt
    19021 ggccctacag accgagttag ccttatttga ggagcttaag caggattatg agcttaggca
    19081 ggacttgctt aagttgtgtc cagatgctag agcgttgcgc tgccaattac ttcatcaaaa
    19141 gcgccagctt gacctgcatc cattggttgc tgatctgcgc ttggcacagg ttgatttgca
    19201 ggaggttttg gcgacgattt cgacagctat tgcagaagca gtgtctgagg atattcttgt
    19261 cgacacagga cttcccttgg cgacaaatag acctcgacat gagcttggac cgtatcaaaa
    19321 tataaaagaa aagagtacct aaatgtttca aaaacagcag agaattgggc tggttatcta
    19381 cctgtattac aatcgagacg ctagaaaagt gatgaaatat ggtgacttgt actaccattc
    19441 caggcgttct cgataccttg ttatttacat caataaagag gacatggaag aaaagctaaa
    19501 ggacattagt cggctaacat ttgtcaaaga ggtgaaggta tcagcctttg atgacattga
    19561 ttgtgatttt gttgggaatt tacatcgtga gcctctagag cctcaagccc tacctgagca
    19621 gggctaagta ggcctgatcc tgtcttatat agcatgtctt agctcatcaa ttgctcaaag
    19681 ctgatggatc agccctgctg gcttgcttag gcaaagaaaa taagagctga gacgattgtc
    19741 atttatcgag tggctgctca taggctttga ggtgtgaggc acaagtctta ggctgctgct
    19801 ttgagggctg gctttttatt cctatcgcct aaaaggcagc acaaaaaggc ttttttctga
    19861 tctggcactg cccaatgaat tggcagtgct ttttcaggca aattttggta aaatagaggt
    19921 aacgataaac aaaggaataa agatgactag aggaaaatta ataacgtttg aaggtccaga
    19981 cggagcagga aaaacaacgg tgctggaaag actggtgcca ctcttacagg cagctctagg
    20041 acaaaccatt gtaacaacga gagagcctgg aggcgttgcg attgctgaga agattcgtca
    20101 gctgatctta gatgtcagtc acacgaccat ggacgataaa acagagctgc tgctctatat
    20161 tgcagcaaga aggcagcatt tggttgaaaa gatcatgcca gctcttgagt caggacactt
    20221 ggttttggtg gatcgtttta ttgacagttc agttgcttat caaggcgccg gaagagggct
    20281 ggataagcaa gccattcaat ggctcaatca ttttgcaaca gatggtgttg accctgattt
    20341 aaccctgtat tttgatgtgc cctcagagct tggattggca aggattgcac aaaatactga
    20401 gcgagagatc aatcgtcttg atcttgagca attagatttg caccagcgtg ttcgtaaggg
    20461 ctatctggag ctggctttgg aaaatcccca gcgtattgtc aagattgatg catcacagga
    20521 cttagaaagc gttgtgtcag cggctttagc tgccattatc acacacagtc aagcatagca
    20581 ggaggttagg aatggatttg gctcaaaagg ctcctagggt ctatcaggcc tttcaagaga
    20641 ttttgcaaaa aaaacgtcta aatcatgcct acctcttttc aggtgatttt gccaattttg
    20701 acatggctct ttttttagcc aagactcttt tttgcgaaca aaaaagaggc aatgctcctt
    20761 gtcatcactg tcgtgcttgc cagctgattg agcacaatga cttttcagat gtcaccatct
    20821 tagagcctgt cggtcagctt atcaagactg ataccgtcaa agaaatgatg acaaattttt
    20881 cgcagaccgg ctatgagggc aggcggcagg tttttatcat taaggattgt gataagatgc
    20941 atgtcaatgc agctaacagc attttaaaat atatagaaga gccacaaggg gattgctata
    21001 tgtttttact aacgaatgat gacaatcagg tcctaccaac gatcaagagc cgtacacagg
    21061 tttttcactt tccaaaagat gagcactacc tctctgagct ggcccaaaaa aaggggcttt
    21121 tgaaacatca agcagacctc ttagccagat tagcagccaa tgcccagcag cttaccgctt
    21181 tttctgaaaa caccaggctg ttggagctga tggcgcaggc tgagcgtttt gtttccatct
    21241 ggtttcagga taaggaacag gcttatctgg agcttaatcg cttggttcag ctagcagagg
    21301 aaaaagagga gcaggacatg gcactaactc ttttaacctt aatcttggcg aaggactaca
    21361 gtcgacaaaa tgcttttacc tatctggagg ctgtttatca ggctagactt atgtggcaaa
    21421 gcaatgtcag ctttcaaaat acgttagaat atatggtgat ttcatgataa gtacgattgg
    21481 aattaaatat tgtgacacct gctctgtcag gtacgttcaa accgatcagg cctttcctgt
    21541 gcaaaccaag cttgtcatat ctgatggcaa gggcagtcga ttggcagtgg tcaattctcc
    21601 gataaaaagc ttttgtaagg acgacctgcc aaaggatatg ccctctgttt tgagacctgc
    21661 caatgacatg gactacaagg cttaccagca aaaccttcag ctagcagccc agtcaaagca
    21721 aaaagtagca gagatgattg acagaaatgg cttagacatg accttggttg acattgtttt
    21781 ctcccttgag agacgttatg ttttgattac ctttaccgct caggagcgtg ttgattttcg
    21841 ccagctcctc aaggatttgg ctgcctattt caagacaagg attgagctgc gtcagattaa
    21901 tagtcgtgag gaggcaaggg tttatggagg gctgggtccc tgtggtcgcc cactatgctg
    21961 ttcaagcttt ttaggagagt ttcctccagt ctcaatcaaa atgctaaaac atcaagggct
    22021 gtccttgcat tcggcaaagt ctttgggctg ctgcggtcgc ttgctgtgct gcctacaata
    22081 tgaggacgat ttttatcaag aaagtaagaa aaaatttcct gattatggta ctatagtaag
    22141 aacagcgcag ggaccaggtg aggttgcagg aattgatctt tttacagata ccattcaggt
    22201 tcgctttaag gaccagctgg ccttggtaac ctatgcttta gaggaggtta aagttagtga
    22261 ataaaaaaga actgtttgac gcttttgatg gcttttcaca aaacctgatg gtgactttag
    22321 ctgaaattga agcaatgaaa aagcaggtcc aaggactcgt agaggaaaat actatcctta
    22381 ggcttgaaaa caccaaatta cgtgagcgct tgagtcaatt ggagcacgaa aatctggcca
    22441 agacctcttc taagcagggc aaggaccact tggagggcat ttatgatgag ggctttcata
    22501 tctgcaattt tttctatggg caacgtcgtg aaaatgatga agagtgtatg ttttgtcgag
    22561 agctattaga tagaaagtag agtcatgcaa atccaaaaga gcttcaagga agaaaaagag
    22621 tcaggggttc tctatctggt gcctacccct attggtaacc tagaggatat gacctttaga
    22681 gcggtcaatg ttctaaaaga ggtggatatt atctgtgcag aggatacgag aaatactggt
    22741 ctgttgctca agcattttgg gataaagaca aagcaggtaa gctttcatga gcataatgct
    22801 tatgataaaa ttccagattt gctggacctg ttgttggctg gaaggtcatt ggctcaggtc
    22861 tccgatgctg gtatgccctc tatttcagat cctggtcatg agctagtcag agcagctatt
    22921 gatcgagata ttactgttgt tgctttgccg ggtgcttctg cgggcattac cggcctcatt
    22981 gctagtggct tggcgcccca gccccatctg ttttatggct ttttgccaag aaaagctggg
    23041 cagcaaaggg catttttgat gactaaggca gattatccag agactcaaat cttttatgaa
    23101 tctccttatc gtgttaagga tacgctaaca aacctgctgg cctgctatgg ggatcgccag
    23161 gtggtgctgg tgagagagtt aaccaagctt tttgaggaat accagcgtgg tcagatttca
    23221 gaggtcttga cctatctagc agaccatcca ctcaagggtg agtgtctatt gattgtggca
    23281 ggtgccaatc aagctgacgc atcagagcct gctgaggatt tggatctgct agcacttgtt
    23341 caacaggcta ttgctgctgg catgaagcct aatcaggcga tcaagacaat cgccaaagac
    23401 tataaggtga atcgccaaga gctctatcag caatttcatg ggcttggcta gactggcttt
    23461 taatccggac tagtcgcctg attgagagaa tctctagtag gccaagcaaa ggagaggtac
    23521 tcaagtaagg gctaatagct gtcttttgca cttctgagaa ttgtcattaa tgtaagcaga
    23581 tagatttgtc tgcacactaa gagagctagt cagttctctt tttttggctt cttgtcaact
    23641 ttaggggggt gactgataac tagtacctag tgaggaccag actggtgctt tttttgtgtt
    23701 gttaatagca atgagaagct tgcttttaat gtttttaagg ttcctaaagc cacaggcttg
    23761 tcgcttcacg ccttccctta atggtcactt tgcagtctta aacgaaaaaa atgctcccat
    23821 ttaggacgtt tcaacgactg tttaggatat ggaggaatgt tttacaaaaa aagcgttata
    23881 ctaaatatgt caaggttgca actggacaac atcgattttt agggagtatt tgcaatcaat
    23941 acaataattt gacgtaatgg ctacagaaat gcttgctagc tttgaaggag gaaaaaataa
    24001 ttgggctgcc aatgtgtcag gtgtgattgg agcaggaagt gcaggcgcag cacttggatt
    24061 tccagtatgt ggagtagctt gtggatctat tggtgtcaca ggaggctttt agaaatgaga
    24121 aaaacagaaa gattctgagt ttggaacctt gttttaggag gataatagaa atggaacatt
    24181 atagagcatt agcaataagt gaaatgcaag atatttcagg aggaaatgca gcaggtaatg
    24241 ctgttatcgg gggattagga ggtctcaaga caggaattac attttgcaaa atacctcatc
    24301 cggtgctaaa aggagtatgt atagacggct ttactgcttt aggagcatgc ttggcatata
    24361 aggtaaatta gatgttattg attacttttt caggtcttta tgctttaatt tttatctata
    24421 tactggttga cagtgctaag aggggcaaag aaggggcttc ttactttatt tttttaattt
    24481 tttatttctt atcgactact ataagcaatg taaatcttat atcccttgtg accttactat
    24541 gttttttagc tatttatata gaaaaaaggt aaattaagtt ttgtatggtt cgtttagata
    24601 ctttttcaac agtttaggga gtatttgtaa tcaatcagaa atgctggtaa atgctgaagg
    24661 tcggctatgg atacgcactg gaggtgtaag aaacatcgat gctggtactt aaaagtagct
    24721 tggtgtcaga tagtgagtgg cagtgagggt tcataccaaa atggtcatta aatagtgatt
    24781 gatagctggt gaaggcaata aataagacca aaataattct tctcattcta ccaataattg
    24841 ctttttttat tcggctgggt gatctattct tggttgaggg atagcaaagt ccttaccttt
    24901 accttatggg ctctttgggg gttatcatat aagggagtaa gcctggttaa gagagtttta
    24961 gcgctttaaa attgtaaaat cagattattt aatgtatact agaggaaata agatgaataa
    25021 agacggaagg tcaatacaat gataatcaaa aaactttcag taatagctct tacgagtcta
    25081 tccttaatca gcctatcagc ttgtcgtcaa cagaatcagg ctctaggtca aaatggcagt
    25141 gctcagaatc ataggaaggc aagtgtttca gaggacaagg ccaaggaact tgcctttaag
    25201 gacgcctcaa tcacagcagc tgacgctcaa aggctcaagc tgacgaaaga aacagacgat
    25261 ggtagagtgg tctatgatat tgagtttgat gctaaggatc aggagtatag ctataccatt
    25321 gacgctaata ccggtgagat cctagaaaaa tcctctgagc caatcactga ggctcctgct
    25381 tcagctcaag cagctggtgg tcaggctgat caagcagctg gcatttcaga ggacaaggcc
    25441 aaggagcttg cttttaagga cgcctcaatc acagcagctg acgcccaaag gctaaagctg
    25501 acgaaagaaa cagacgacgg tagggtggtc tacgatattg agtttgacgc caaggatcag
    25561 gagtacagct atactattga tgctaatagt ggagatattt tagaaaagtc ctctgagcct
    25621 gtttacgatt aaaaagctat caccgcttat gtgataaaag cctgtaacat tcctaagcct
    25681 ttatatgcta aaagggctta ggttttttgt tgttccttgt tgtgcctgat agagctggag
    25741 cttgttggca gccatttagg cgctagccta tagcccgcct ttgttgctgg tatttggctg
    25801 tgataagggc tgtttagttg aaatgatagg cattatcagc ttaggatttg gcagagtgat
    25861 acttttatga ctagaaggat aggctatggg ctgtaaatgt tgtataatag agtagaaagc
    25921 gcttgctatg attgagagag cctatctcag cagcgataga atggaggaca catgggaact
    25981 gaaacctata ttatggctat tgatcagggc acaacgagct ctcgtgccat tattttcaat
    26041 aagaaaggag aagcgctggt tagtagtcaa aaggaatttc cacagctttt tccacaggct
    26101 ggctgggttg agcacaacgc caatcacatt tggaatttgg tgcagtctgt tattgcagac
    26161 gcctttatcg agtctggtat aaagccagag caaatagaag ctataggcat taccaaccag
    26221 cgtgaaacaa cggtagtctg ggacaaacag acaggtctgc ccatctataa tgctattgtg
    26281 tggcaatcta gacaaacagc ctccattgca gagcagctaa agcgtgatgg ctataccaaa
    26341 atgatccatg aaaaaacagg cctggttata gatgcttatt tttctgcgac caagctcaga
    26401 tggcttcttg atcatgttcc gggggctcaa gagcgagctg aaaggggaga attattattt
    26461 ggcacgattg acacctggct ggtttggaag ctaacggacg gggcggtaca tgtgacggat
    26521 tattctaatg cagcacgtac catgctatac aatatcaaag agctaaaatg ggacgatgag
    26581 atattggcct tgctgaatat ccctaaggcc atgcttcctg aggtcaggtc taattcggaa
    26641 atttatggta aaacggcttc ttttcatttt tacggaggag aggtagctat tgctggcatg
    26701 gcaggtgatc agcaggcagc cctatttggg caactggcct ttgagcctgg tatggtaaaa
    26761 aatacctatg gcacaggctc ttttatcatc atgaatactg gtcaagaggc tcaattatcc
    26821 agcagcaacc tgctaacaac gattggatat ggtattaatg gcaaggttta ttatgcctta
    26881 gaagggtcta tctttattgc tggctctgct gtgcaatggc tacgagatgg cttgcgaatg
    26941 ataaaaacct cttttgagtc tgaacagcta gccttggctt caaccaatgc tgatgaggta
    27001 tatgttgtac cagcctttac aggtcttggc gctccttatt gggattccaa tgcacgcggc
    27061 tcagtatttg gcttaacgcg tggaacaaca aaagaggatt ttgttaaggc taccctacag
    27121 tctattgctt atcaggtcag agatgtgatt gataccatgc aggtggactc agggatcact
    27181 atccagcaat tacgtgttga tggcggagcg gctatgaata acatgctcat gcagtttcag
    27241 gcagatattt tagggattga tattgctcgt gctgaaaatc ttgaaaccac agctctagga
    27301 gcagcctttt tagccgggct tgctgtaggc tactggaagg acatggagac gctaaagcaa
    27361 ttaaatgcta caggtcagct gtttaaagca agcatgagtg agtctcgccg agaaaagtta
    27421 tatcaaggct ggaaaagagc tgtcaaagcc acacagtttt ttgcagagga gctgtaagaa
    27481 tcaagccttt taaagaaaca gagtcccata gctaggtcta gttttgaaca ctagactgtg
    27541 tgatacttgg tcttttatat cctaagagtg acttttataa tgataatgta gacggtaaac
    27601 agcgtcatgc tgttcaatga ctgataacag actaattaac ggaggttaag atgaaatttt
    27661 tcttagacac agcaaatgta gaggcaattc gtgcgattaa tgagcttggt gttgtggacg
    27721 gtgttaccac aaaccctagc attatctcgc gtgagggtcg tgattttgag acagttatca
    27781 aggaaatctg tgagattgtg gacggcccta tcagtgcaga ggtcaccgga ctaaccgcag
    27841 aggaaatgat tgcagaggct aggaacattg ccaagtggca tgacaatgtg gtcgtgaaaa
    27901 ttccgatgac gacagagggc ttaaaagcaa ctaatgtctt gtcacaagaa ggcatcaaaa
    27961 caaatgtgac gcttattttt acagttagtc agggactaat ggccatgaag gctggtgcga
    28021 cctatatcag tccatttatt ggtcgcttag aggatattgg agcagatcct tatcagctta
    28081 ttagtgattt gcgtgggatc attgatttgt atggcttcca agcagaaatc atcgcagcca
    28141 gcattcggac agctgcccat gttgaagctg ttgcacagct agggggacac attgcaacca
    28201 ttccagatcc attatttgcg aagatgactg agcacccatt gacaacaaat ggcttaaaga
    28261 cctttatgga ggattgggct tcctttaaaa aataggctaa gagcatagag ctctccttat
    28321 attctaatgt ggctgtagcg gttagtttgg gattagctat ttgtaggtgg caggatcagc
    28381 tggtgctttg ctgttgcgct agaattaaca ggcagctggc gcttactgta gccaaaggga
    28441 ggtaccaaag aggaatgctt gcttagctgg caacagctag gcttgctttt tcttatgagc
    28501 ataggtgctc tatctaagac agctgtcaat cacaaaaagc taggaacagc aatgcttatt
    28561 gctagataag aatttaagga ctttatagga ttttgttaaa aatcagttta cttttatgtt
    28621 acaatagaca atggaaaacg tttaattttt agttgtaata cacagagagg ttttacttat
    28681 gacatttgat gcaattgatc agctggcagt taatactgtt cgtactctat caatggacgc
    28741 tattcaagca gcaaattctg ggcatccagg tttgccgatg ggggcggcgc cgatggctta
    28801 tgtgctatgg aatcatgtta tgacagtcaa tccaaagaca agccgccgtt ggtcaaatag
    28861 agaccgcttt atcctatcag caggtcatgg tagtgccatg ctttacagcc tgttgcacct
    28921 agcaggctat gatgtgtcta ttgaggatct taagaacttc cgtcaatggg gctctaaaac
    28981 accaggtcac ccagaggtca atcatacaga tggcgttgag gcaaccacag ggcctttagg
    29041 acaaggagtt gccaatgcag ttggtatggc tatggcagag gcacacttag cagctaagtt
    29101 caatagacct ggctttgata ttgtagacca ctatacctat gctctaaatg gtgacggaga
    29161 ccttatggag ggtgtcagtc aggaggcagc cagtctggca ggtcacttga agcttggtaa
    29221 gcttgtcttg ctatatgatt caaacgatat ttcgcttgat ggcccaacct caatggcctt
    29281 cacagaagac gtcaaggggc gttttgaagc ttacggctgg cagcatatcc ttgttaaaga
    29341 cggcaacgac ctagaggcca ttgctaaagc tatcgaggaa gctaaggcag agactgaaaa
    29401 gccaaccatt attgaagtaa agacaatcat tggctttggt gctgaaaagc aaggaacttc
    29461 agctgttcat ggggctccgc ttggtgcaga aggcattgcc tttgctaaga aatcttatca
    29521 atggacccat gctgattttg aggtgccgca agaggtgact gagcgcttta gacaaggcct
    29581 tcaggcgcgt ggtgagcagg ctgagcaggc atggaatgac ctatttgcag cttatgaagc
    29641 agcataccct gagttagcag ccgaatacaa aaaagccttt gctaatgagg cggcagaggt
    29701 tgagttgcaa gctcacgagc ttggcacagc agtagccagt cgtgtttcta gccagcaggc
    29761 tatccaacaa atctctgagc aggtgccagc cttctgggga ggctcagctg acctttctgc
    29821 ctctaacaat accatggtta aggctgagac agacttccag ccgggtcatt atgctggtcg
    29881 taacatctgg tttggcgtac gcgaatttgc aatggcagca gcgatgaacg gtattgccct
    29941 tcatggtgga acacgtgttt atggcggaac cttctttgtc ttttcaaact acctattgcc
    30001 agcggttcgt atggcagcct tgcagcagct accaacggtt tatgtcatga cgcatgattc
    30061 tatcgcggtt ggtgaagatg gtccgaccca tgagccaatc gagcagctag ctagtgttcg
    30121 atcaatgcca aatctgaacg ttattcgtcc agctgacggc aatgaaacaa acgctgcttg
    30181 gaagcgtgcg atcgctgaga cagaccgtcc gacaatgctt gtcttaacac gtcaaaacct
    30241 tcctgtactt gaaggtacta aggaattggc agaagatggc cttaataagg gagcttatat
    30301 cctgtcagag gcaaagggtg accttgatgg gattatcatt gcaaccggct ctgaagtcaa
    30361 gctagcaatg gatactcaag ccgctcttgc agcagatggt atccatgtgc gtgtggtatc
    30421 aatgccatca caaaatatct ttgatgagca gccagcttcc tacaaggagg aaatcctacc
    30481 agcagcagtg acaaaacgtc tagctattga agcaggctca agctttggct gggcaaaata
    30541 cgttggcctt gcagggaaaa cactgaccat tgatacatgg ggagcttctg caccgggcaa
    30601 tcgtatcttt gaagaatatg gctttacagt agagcatgct actgaattgt acaaatcctt
    30661 atcataagtg attaagctgg agcaggcctt atctaggctt gctttcggca ttattagaca
    30721 aaaaaacgca tgatgttcaa ccctttttag ggaggacgtc atgcgttttt gtttcagatt
    30781 taatagtgct actgctcagc cttgcagatc tatcccgagt tgctagaagc tattgtcaaa
    30841 tagctggctt agcttttctt tctttttagg gttagcagac ctgcgctagc gatgacgcta
    30901 agagctgcca gactaaagaa tggatggctt gcctctcctg tagctggtag gactgctttt
    30961 ttgcttggtg ttgactgagg tgctggtgcc ttagggctag ctgactgctc tgaagccttt
    31021 ggagctttcg gtgcaggagc cttttcagga gcctgtggct tctctggcat ttttggtgat
    31081 tctggtgcct ttggaactga tggcttggta tcctttcctt ggtcaccctt tggctgttgc
    31141 tcaccatttt caccgcgttg accttgctcg cctttttcgc cacgttgacc ttggtcgcct
    31201 ttttcaccgc gttgaccttg gtcgcctttt tcgccacgtt gaccttggtc gcctttttca
    31261 ccgcgctgac cttggtcgcc tttttcgccg cgttgacctt g
//
LOCUS       DARYLJ010000027        30257 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYLJ010000027 DARYLJ010000000
VERSION     DARYLJ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30257
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            116..328
                     /locus_tag="TU746_001097"
     CDS             116..328
                     /locus_tag="TU746_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL0891447.1"
                     /translation="MSQQHRKWSALVEQRLKEKDWTKGDLALAVGLRSSGTITDLLAK
                     GKGSVDLKVRVSKILGIREPWELFER"
     gene            401..652
                     /locus_tag="TU746_001098"
     CDS             401..652
                     /locus_tag="TU746_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891448.1"
                     /translation="MDNILMSLSDWIKEIIEKTVNRLVQIKLDEANAELLTREKVADR
                     LNMSPATFDKYYRYDKNFPSELPGVRWKKAEIIAWLNNK"
     gene            928..1269
                     /locus_tag="TU746_001099"
     CDS             928..1269
                     /locus_tag="TU746_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891449.1"
                     /translation="MTQAERIREFYKENPTASYDEVAEAIGTTNSNVRANIAKDIKAG
                     RCVRLEDKSLDYSAHFGATEALADLVDWKNDTRREWVEMLTRAAEKETDSNTMRLLIK
                     EANKLMKEVTK"
     gene            1269..1751
                     /locus_tag="TU746_001100"
     CDS             1269..1751
                     /locus_tag="TU746_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEL0891450.1"
                     /translation="MAKLYELVGEYRDLYELNLDDETLKDTLDSIDWADRLSEKVEGY
                     AQVIETALAEAKMFEEAEKKFKAKKEAAKKKAAWLQGNVFDAMKLTNQTEIKSGIFTV
                     RIKQNPESVKVDEELLPKKYFNKKITVAPDKTTLKELLKSGKKIKGAELIRTEKLVIK
                     "
     gene            1748..2221
                     /locus_tag="TU746_001101"
     CDS             1748..2221
                     /locus_tag="TU746_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891451.1"
                     /translation="MMILAIDPSSNRIETSTTGIVLLDNARLVDYWVVPFGAENFKKW
                     FKDIGRTLEFDTVVVEKFEVRDNDYSRDNSVVETISAIELCYPDLVLQRNAGYQTDIP
                     NGLLKALGLWSFDKSHHNDVRAAARLGLFWAQRNDIEEVIVDIGNRITQMASGSS"
     gene            2181..3356
                     /locus_tag="TU746_001102"
     CDS             2181..3356
                     /locus_tag="TU746_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891452.1"
                     /translation="MAIELRKWQAEAVKRSDRDCPGIFLEAYGGRGKTICAFEIAKHK
                     EAKKVLVINNRLAILNGWNNTHQDLGYVNDFELEIMTDRRLQNRLASGESIECDVFVI
                     DEWQNMSSDANVKAYKKVKRGYTVGLSATPIRKKGQNFYPLEKTIFGMAEPNQRENWQ
                     LAHGKMKYSKFSYSKQEWDDFRNYESYVANLPNFFRWEDVEAIEEAEENNGFEVIFEP
                     VWCPPANPKELEQFRSLNIVGKDGKFAMAKQTFGRKIFERYLIQTGFEIDFPKLKAIN
                     ADTPMLIQLDLLLASHTEMLIVSKSKQIVEVIRERHPEIGIWTGDKKDALEQTNVVAT
                     TQVLGVGVDGLQYKFKTIVVLDPVNPSDGDYDDYRQLLWRVTGSRQQHDVRVIEFYF"
     gene            3366..4076
                     /locus_tag="TU746_001103"
     CDS             3366..4076
                     /locus_tag="TU746_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEL0891453.1"
                     /translation="MAEHKESGIFIVLRCIQADLIAPKGQYNSFGKYAYRSAEDILEA
                     LKPLLKKYDASIVLSDEIVQVGERYYVEATATLYAMGECVGNKAYAREDETKKGMDGA
                     QITGAASSYARKYALNGLLAIDDNNDADTDAYHNQNNQSAGKTQKTNQKQASQQESTA
                     KAPAKNNGSKTITGAQAKAIRTELKNMAEATGSPAAAIGNWFIGKMGVDKPENIPAER
                     LKEAQQIIADAKKVKGIE"
     gene            4077..4469
                     /gene="ssb"
                     /locus_tag="TU746_001104"
     CDS             4077..4469
                     /gene="ssb"
                     /locus_tag="TU746_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0891454.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGVLIGITGRIQTRNYENQQGQRVYVTEVVADNFKM
                     LEYRQQQQQEDSFDNNNPMDIQADDLPF"
     gene            4483..5310
                     /locus_tag="TU746_001105"
     CDS             4483..5310
                     /locus_tag="TU746_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEL0891455.1"
                     /translation="MGMKEYALAYQKKGFSVLPISPTGKKPMIAFADKPPMTAQEIED
                     FWTQYPDSNIAVRTDKFFVIDIDLHGKANGFESLANWEHLDLITPTLQAKTASGGKHI
                     FYFKHPDVSMTQMIGFLPGVDVKAHLNNYVLVAPSKTPKGVYAWDKDKSKEDGTMVTA
                     SRKLVMAIKQEYNKKNPGSDLDNIYYQISKGAGKRNRTTELFEMIVLGFGDQGGRNDT
                     LARFVGGLLSRSVDPECILRLAETANNNSVEPLGKREMRRTIESMIKKHMRGGGHNR"
     gene            5294..6694
                     /locus_tag="TU746_001106"
     CDS             5294..6694
                     /locus_tag="TU746_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL0891456.1"
                     /translation="MATIGEIVNISIKQFSRRKKKILSEEGEQIEVESIVADSPRNVL
                     LAMKSDNKLNDFLRHNEFTGEHEIVEDVKLDAIQLRRGQLPSTFESYLSVYLENHFKT
                     VFKAGALRDGIEAFFAEKTYNPVQEYMEHAYESWDHRERLAQVFQTWLGAEDSIFVQR
                     IAVMFFVGAVSKVFNPWVKFDYTLDLVGGQGAGKTTFLQKVAVEWYTDSAKDFMDKDN
                     YEIMLKSLIVNDDEMVASRKTTFDELKAFVTKTELSFRRSYGRRAEKFPKNFVIARTS
                     NKVEYLGDKTGERRFLPVLVDADQQLVKPFDMTDRDVLQLWGEAVAIYKKGFTLTFDD
                     DFEDELAVYKERFTYKDEAESQIYDYLDMLVPDEWEEMSVVQQHQYTWAYFNNGSYRN
                     ESGFVYEGVKLQASVSAKQILKNVFDIDSARGERIARKIKLIMDNHQDWEYRIKKIKG
                     RTVRAYFKKNMQNEVM"
     gene            7050..7244
                     /locus_tag="TU746_001107"
     CDS             7050..7244
                     /locus_tag="TU746_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891457.1"
                     /translation="MSYKVLVYFDNMLDEEYKFKTEKDASKCHDQLRRKYQGQRLYKV
                     KMEEVEEEVIITNFREVDHD"
     gene            7237..7464
                     /locus_tag="TU746_001108"
     CDS             7237..7464
                     /locus_tag="TU746_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891458.1"
                     /translation="MTKDDFLTGFVLILLAACIFAVGFAIGHDYSSEHYEQKITDLQI
                     QLVSTQQQLKQSREQNQSQTKRIANLTGNGG"
     gene            7475..8164
                     /locus_tag="TU746_001109"
     CDS             7475..8164
                     /locus_tag="TU746_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL0891459.1"
                     /translation="MEIKCGNCLELLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGADLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLAVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVSGAEKTQH
                     PTQKPVALMRDIITRHTTKRAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAN
                     KRIAELTGNGG"
     gene            8166..8957
                     /locus_tag="TU746_001110"
     CDS             8166..8957
                     /locus_tag="TU746_001110"
                     /inference="COORDINATES: protein motif:HMM:TIGR00675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL0891460.1"
                     /translation="MLRVFEAFAGIGTQRMALRNLGIPHEVVAIAEIDKFAIKSYEAI
                     HGPVNNLGDISKINPDTIPDHDLFTYSFPCQDISVAGKQAGLDIDSGTRSGLLWECQK
                     VIVAKKPKYLLMENVKNLVGKKHKPNFDKWLDWLESQGYTNDWQVLNAKDYGVPQNRE
                     RVFCVSILGEHKPYIFPEKQELTIRLKDILEDDVDEKYYLTTNKANELLATIVRENDV
                     SERVVVDSTIKKPKIKNVMNAVIGRYDAGIRNQQSVGGAVIELIE"
     gene            8941..9444
                     /locus_tag="TU746_001111"
     CDS             8941..9444
                     /locus_tag="TU746_001111"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL0891461.1"
                     /translation="MSLLNKNATKKGYLVADDGDGIDTAYPDSKTRKGRVQKNMSHTI
                     TTDDSKAFLIGASRGRDPENPNDRSAGNQNLQQRLEINKNGTSNTITSVQKDNYAVEF
                     PDYRIRKLTPLECWRLMGCSDEDFEKAQSVNSNSQLYKQAGNAIVVDVLEAILKQLFL
                     TEAQNEH"
     gene            9434..9952
                     /locus_tag="TU746_001112"
     CDS             9434..9952
                     /locus_tag="TU746_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL0891462.1"
                     /translation="MNIEEAKQKLHNMAYRDLQTKPYDLKLADVIQILNQIKLDKPQP
                     EIPQFVADYIDDMHKNARTLRYAFKYMESNIKMHKWCVFEKQETFVNAFLYGYTIEKE
                     KLYTVEIPNPKNGIAHRHIMLVKTTDGRVVLSEVVDSHIHLRDDLRLTESEIRKDFDW
                     AWREEFPKEVTE"
     gene            9979..10278
                     /locus_tag="TU746_001113"
     CDS             9979..10278
                     /locus_tag="TU746_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891463.1"
                     /translation="MNYDKKKSDLKKRLIIGFTLLPISIVLSGFVIKYGWNNILSTID
                     GVPPINLPQAIAIDVLVSFIIAKTNAEGDFATEVGRAFISPLMTLLLFWVVTLFM"
     gene            10295..10468
                     /locus_tag="TU746_001114"
     CDS             10295..10468
                     /locus_tag="TU746_001114"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891464.1"
                     /translation="MTEELGVLLDKEGVEYVKMVFDDGFVWTIRNPLNAALLKRQDAE
                     QFPQFTWVPLTDL"
     gene            10805..11245
                     /locus_tag="TU746_001115"
     CDS             10805..11245
                     /locus_tag="TU746_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL0891465.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALMSFSELYKEGMLLVEKMEKSWN"
     gene            complement(11643..12020)
                     /locus_tag="TU746_001116"
     CDS             complement(11643..12020)
                     /locus_tag="TU746_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL0891466.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(12072..12257)
                     /locus_tag="TU746_001117"
     CDS             complement(12072..12257)
                     /locus_tag="TU746_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL0891467.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            12373..12708
                     /locus_tag="TU746_001118"
     CDS             12373..12708
                     /locus_tag="TU746_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL0891468.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            12871..13338
                     /locus_tag="TU746_001119"
     CDS             12871..13338
                     /locus_tag="TU746_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL0891469.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            13353..15107
                     /locus_tag="TU746_001120"
     CDS             13353..15107
                     /locus_tag="TU746_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL0891470.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKKVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            15104..15274
                     /locus_tag="TU746_001121"
     CDS             15104..15274
                     /locus_tag="TU746_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891471.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            15267..15533
                     /locus_tag="TU746_001122"
     CDS             15267..15533
                     /locus_tag="TU746_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891472.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEALRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            15567..16787
                     /locus_tag="TU746_001123"
     CDS             15567..16787
                     /locus_tag="TU746_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0891473.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAHISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            16765..17430
                     /locus_tag="TU746_001124"
     CDS             16765..17430
                     /locus_tag="TU746_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL0891474.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            17455..18642
                     /locus_tag="TU746_001125"
     CDS             17455..18642
                     /locus_tag="TU746_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL0891475.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASIEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEALRFEGKDEVLIPLNQTTPVAPDTDGIKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKASGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQSMDTLKDENGRYLLQDSITSASGKVFLGKPVFVLSDDVIGKD
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            18787..19089
                     /locus_tag="TU746_001126"
     CDS             18787..19089
                     /locus_tag="TU746_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0891476.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            19086..19433
                     /locus_tag="TU746_001127"
     CDS             19086..19433
                     /locus_tag="TU746_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL0891477.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            19430..19807
                     /locus_tag="TU746_001128"
     CDS             19430..19807
                     /locus_tag="TU746_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0891478.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            19804..20229
                     /locus_tag="TU746_001129"
     CDS             19804..20229
                     /locus_tag="TU746_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891479.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLINVRKYRYFDFY"
     gene            20245..20835
                     /locus_tag="TU746_001130"
     CDS             20245..20835
                     /locus_tag="TU746_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0891480.1"
                     /translation="MGKVKFGLRDFQYAVLGDDDQLKTKTGGIKSLPGMKSAKLDITN
                     ELVTVAADDGPYVVLSGGITETKLEIEVLDLTSDARKDFFGIKEEDGIEKYNKELTPN
                     DVACMFRTSDENGKAIWIGLLKGKFNIPGMEMQTKEGAPDPKSDTVTGNFVSRGKEGD
                     VIVIGRESASGFKLEKFKEFVFAGATDIKKGENFEM"
     gene            20887..21213
                     /locus_tag="TU746_001131"
     CDS             20887..21213
                     /locus_tag="TU746_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891481.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            21261..21410
                     /locus_tag="TU746_001132"
     CDS             21261..21410
                     /locus_tag="TU746_001132"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891482.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            21423..25082
                     /locus_tag="TU746_001133"
     CDS             21423..25082
                     /locus_tag="TU746_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL0891483.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRSLATETSVFTRFGKAAERIGGKMKSFGDSVAGVDAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGVKTGDILSFSRTMIYLGESTNLSAEEAATSIAKIANITGLASSEY
                     SRFGSAVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQSLSAIERAVASGGDNLNKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDDLGLSGIRQSNMLKSLGLASETLGKALDTSNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIVKWGLIAAAAGPALSIFGKGVGIIGGTIQAMGKMSRGLGTLSGWLRTFRTGA
                     VAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGIKVSQVQANELQRFKNKVDEANLAMTTFGVRSANNLDKIKTSFKALADEIEALQNK
                     KLKKDLKLAEKLGLSQETIEEIRRQADQTVATVRGMSDKVVDIYRRAKEERRSLTEEE
                     KTVVTKNLNDMIQTELSLMNYSKKEKIAILKAMNGEIETLNYEQLKKAQEVAQKMIES
                     ENKTYKKRRSNLKEMYDNIKGDSETAVRAREEIHRQLETLEDSHTAKMESLGERYLKI
                     RKKLLVDPALDPRVKQAMIDSLDKEFEKLGLSFEKLSKRSEEASSKTKISMQDMTSSF
                     RASIGEAISSLQGWDNLTPQEKQLLIDGNKAVSEILNSKTLLEQWQALTPQQKELLAK
                     NLTQDPTLSAQQAIDNVKQRVPADVKASDKTAPDVASADRAVNRPKQKGPAIIRAQDN
                     ASSVASGVIGWLNSIPRTVTSTITTIVRKITGHKTGTDYHPGGLAMVNDQKGPLYREL
                     ITLPTGESFIPEGRNVILPLPRGSKVLRASRTKQLFSHYANGIGFNDTKIASLTTRLK
                     SVQDKGQVIVNTDPQLAELIKLLKDRDNRNVTNNYTLNATNRSNSDDMFNQENMRRLL
                     RELAYYTNGEKGRLA"
     gene            25082..25789
                     /locus_tag="TU746_001134"
     CDS             25082..25789
                     /locus_tag="TU746_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0891484.1"
                     /translation="MRYIEFNGKKSDSFGLLLERERSIKSTSNDVDLIEVDGRDGVLL
                     KDNGRLKAIEQDFPFSLVGDVAVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVSLVNGGTLQNLGNVQSKPILKIKGTGN
                     GVLTINGFETGLENVQGELIIDMERHLVYKDILSAWDNIVRTERHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            25786..27927
                     /locus_tag="TU746_001135"
     CDS             25786..27927
                     /locus_tag="TU746_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0891485.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVRVTRERNGNYSLYIKYP
                     LDGVFASVFKEELKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEQEQPEEQLVTLPEFILDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQRELDERNQKELEEFRETLKNLSL
                     PEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTDGKTRYNKNLL
                     VGDPNRVKKIDEDFIEVEANDGGFRRGETYTISFSQTCELLKKVAITLTQANNKGVKL
                     VLIPTKAKMEAQTFNLSKDKEVISVYPLSYRAVLTGDWYKSKQIELNAAEVQNLALEM
                     SYRDVVDSNNASLILDWSPNPDVIFDGNGGS"
     gene            27927..28688
                     /locus_tag="TU746_001136"
     CDS             27927..28688
                     /locus_tag="TU746_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0891486.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGPQGPQGLSGDRGPIGQTGPQGKQGVSVQSASVDSEGYLTVLL
                     DNGQSFKSDSSLKGSKGDTGPKGADGKMTFEQLTPEQKQQLKGDKGDPGPKGDIGPRG
                     ATGPQGPKGEPGINGMDGPRGATGPRGLQGPLGKDAVLPDDVVRRGELAAYLLRSEYK
                     AKGSGSGLSYKVVTQSEYDDLYDYNDNELILVTEG"
     gene            28690..29307
                     /locus_tag="TU746_001137"
     CDS             28690..29307
                     /locus_tag="TU746_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891487.1"
                     /translation="MAYKLYTKADVGDNMLLVAGRPLPDDTKRLKIQRETLDVLTITH
                     YGSYDMVHLKSTVKKAYSKNTVVTPVSAAASKPKAKPKHVLNFAKANKVYIGSTRVIA
                     VYLGDRLIWSDKHSSGTKTVSVVGSLDIRQSQKMLYLYLIAPDVADVKSKRIKSIAIN
                     GVKLSSTAQISFEGSSYYYLVTIKQVANIKEIKNIASKNKITLEF"
     gene            29318..>30257
                     /locus_tag="TU746_001138"
     CDS             29318..>30257
                     /locus_tag="TU746_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0891488.1"
                     /translation="MSRDPTITLDESNLVIGQDGRMHYTFVAQDDNQKVRLASNCLGT
                     AHFNQLMIERGGQATDYVAPVVVEGSGKPTGLFKDLKELSLELTDTANSQLWSKIKLT
                     TNGMLREYHRDHIKTEIIESADGIAKRIADDTGQKLALINETINGIRREYQDADRQLS
                     ASYQAGIDGLKTQLANDKIGLQAEIKLSAQGLSQKYDDQIRQLYSKITTTSSGTTEAY
                     ENKLEGLRAEFTRSNQGLRTELESQISGLRSVQQSTASQISQEIKDRTGAVSRVQQDL
                     NSYQRRLASAEGNYSSLLQTVKGLQSTVSDPKGKIQS"
BASE COUNT        10163 a         5145 c         7010 g         7939 t
ORIGIN      
        1 agtaggaggt gagaatttgg ataatttaca aagacgttta gaacattttg taatcagagt
       61 atcgagacat tgcaacctca cgtttttatt ttaattatat cagaaaggag aataaatgag
      121 ccaacaacat cgaaaatggt cagctcttgt tgaacagcga ctaaaagaaa aagattggac
      181 caaaggcgac ttagcactag cggttggttt gcggagttcg ggaacaatca ctgacttact
      241 cgcgaagggt aaaggtagtg ttgatctaaa ggttagagtt tcaaaaatcc ttggaattcg
      301 tgaaccatgg gaattatttg aaaggtaaca aaaaagtccg acgggaatcg gactcaaaac
      361 aaaaatttac tacttagatt atatcacaaa ggagctaact atggacaata tcttaatgag
      421 tttgtccgac tggataaaag aaattattga aaaaacagtt aacagattag tccaaatcaa
      481 attagatgag gcaaatgccg aattattgac tagagaaaaa gtagcggaca ggcttaacat
      541 gagcccggct acttttgata agtactacag gtatgataaa aattttccaa gcgaattgcc
      601 aggcgttcgt tggaaaaaag ctgaaattat cgcctggcta aataacaaat aagacttttg
      661 gacgaggtct aatcacaagg gaagaaacac tggaaaacaa ttaggagtgt aattatgttt
      721 aataaaaaga aaaaattgca gaagtcattc aataatatta acaagcacat tgatagtctg
      781 acgctgtcag aacaagaaaa gcgtaatcta aaaggattgc tccgtaatgt caaaattaga
      841 acaagggtgg cgtgatgaat gcaattggta tgtatagcat tttagagcgg ctagaccggc
      901 ttgaaaaaat cgtatttgaa acagtagatg acacaggcgg aacgcattag ggaattttat
      961 aaggaaaatc ccactgccag ctatgatgag gtggcagaag ctatcggaac gactaatagc
     1021 aacgtcagag ctaatatagc caaggacatc aaggcaggca gatgtgtccg cctcgaagat
     1081 aaatcattgg actactcagc tcattttggg gcaacggaag ccctagctga tttagtagat
     1141 tggaaaaatg acactagacg ggaatgggtg gaaatgctga ctagagcagc agagaaagaa
     1201 acagatagca ataccatgcg attgcttatc aaggaagcta ataaactgat gaaagaggta
     1261 acgaaataat ggctaaatta tacgaactcg ttggggaata tcgggattta tacgagttaa
     1321 atcttgatga tgaaacctta aaagatacgc tagacagtat tgactgggca gacagattgt
     1381 cagaaaaagt tgaaggctat gcccaggtta tcgaaacagc acttgctgaa gcgaagatgt
     1441 ttgaagaggc tgaaaagaaa ttcaaagcca aaaaagaggc tgctaagaaa aaagccgcct
     1501 ggttgcaagg gaatgtcttc gatgccatga aattgaccaa ccaaacagaa attaagtcag
     1561 gaatttttac agtgcgaatt aagcagaatc ctgaatcggt aaaagttgat gaagagttac
     1621 tgccgaaaaa atacttcaac aaaaagatta cagtcgctcc ggacaagaca acgttaaaag
     1681 aactgctcaa atctggaaag aaaatcaagg gagcagaact aatacgtaca gaaaagttgg
     1741 tgattaaatg atgatactag caattgatcc aagtagtaat cgaattgaaa ctagtacaac
     1801 aggaatcgtc ttactagaca atgcaaggct agttgattat tgggtagttc catttggtgc
     1861 tgagaacttt aaaaagtggt tcaaagatat tggcagaact cttgagtttg ataccgtagt
     1921 ggttgaaaaa ttcgaagtta gagacaacga ttattccaga gataattcag tagtcgagac
     1981 tatatcagca atcgaattat gttatccgga tttagttctg cagagaaatg caggctatca
     2041 gacggatatt ccaaacggtt tgcttaaggc tcttggtttg tggtcttttg ataaaagcca
     2101 tcacaacgat gtgagggcag ctgcaaggtt gggattgttt tgggctcagc gcaacgacat
     2161 tgaggaggtg attgtggaca ttggcaatcg aattacgcaa atggcaagcg gaagcagtta
     2221 agcgtagcga ccgcgattgt cctggtatct ttttggaagc atacgggggt aggggtaaaa
     2281 ctatttgtgc ttttgaaatt gcaaagcata aagaagctaa gaaagtactt gttatcaata
     2341 accgattagc tatcctgaat ggttggaaca acacccatca agatttaggc tatgtaaatg
     2401 attttgagtt agaaatcatg acggatcgca gattgcagaa cagattagca agtggtgaat
     2461 ctatcgagtg tgatgtattt gtcatcgatg aatggcagaa tatgtcgagc gatgccaatg
     2521 tgaaagcata caagaaggtc aaacgcggct atacagtagg gctttctgca acgcctatca
     2581 ggaagaaagg gcagaatttc tacccgttag aaaaaacaat atttggaatg gctgagccta
     2641 atcaacgtga gaactggcaa ttagcccatg gtaagatgaa gtattccaag ttcagctatt
     2701 ctaaacaaga atgggatgac ttccgaaact atgaaagcta cgtggccaat ttaccaaatt
     2761 tcttccgttg ggaagatgtt gaggccattg aagaggcaga agaaaataac ggttttgagg
     2821 taatttttga accagtttgg tgcccacctg ctaatccgaa agagctggaa cagtttagaa
     2881 gtctaaacat cgttggtaaa gatggcaagt ttgcgatggc taagcaaact tttggtcgaa
     2941 agatttttga gaggtactta atccagacag ggtttgaaat tgactttccg aaattgaagg
     3001 cgatcaatgc agatacacct atgctaatac agcttgattt attgttggcc agtcatacag
     3061 aaatgctgat agtcagcaag tcgaagcaaa ttgtagaagt cattcgtgag cgtcaccctg
     3121 agattgggat ttggacggga gacaagaagg acgctctgga gcaaaccaat gtagtagcta
     3181 ccactcaagt acttggtgtc ggtgtggatg gcttgcagta taaatttaaa acgattgttg
     3241 tcctagatcc agtcaatcca tctgatggtg actacgacga ctaccgccag ctattatggc
     3301 gggtaacggg cagccgtcaa caacatgacg tgcgtgtcat tgaattttat ttttgaggag
     3361 acaaaatggc agaacataag gaatcgggta tctttattgt tttgcgttgc attcaggctg
     3421 acctaattgc tccaaaaggg cagtataact cttttggtaa gtatgcctat cgtagcgctg
     3481 aagatatcct ggaggctctc aagcctcttt tgaagaaata tgatgcctca atcgtactga
     3541 gcgacgaaat cgtccaggtt ggggagaggt actatgtaga ggctacagct accctttacg
     3601 caatgggtga atgtgtagga aacaaggctt acgctcgaga agacgagacc aaaaaaggta
     3661 tggacggggc acagattaca ggtgcagctt ctagctatgc tcgtaaatac gctttgaatg
     3721 ggcttttggc tattgatgac aataatgacg ctgatacaga tgcctatcat aatcagaata
     3781 atcaaagtgc tggtaaaact caaaagacta atcaaaaaca agcgagtcag caagagtcaa
     3841 cagcgaaagc tcctgctaaa aataatggtt ctaaaactat tactggagcg caagccaagg
     3901 ctatccgaac agaactcaaa aacatggcag aagctacagg aagtccagct gctgcaattg
     3961 gtaactggtt tatcggaaag atgggcgttg acaagccaga gaacattcct gcagagcgtt
     4021 tgaaagaggc acaacagatt atcgcagatg cgaaaaaagt gaaagggatt gaataaatga
     4081 ttaataatgt agtactagtt ggtcgtatga ccaaggacgc agagcttcga tacactccaa
     4141 gtcaggtggc agttgctacg tttacacttg ctgttaatcg cgcctttaag agccaaaatg
     4201 gtgagcgcga agcggatttc attaactgtg tgatctggcg tcagcaagct gaaaatttag
     4261 ctaactgggc gaaaaagggt gtcttgattg ggattacagg acgtattcag acccgtaact
     4321 acgaaaacca acaggggcag cgtgtgtatg taaccgaggt tgttgcagat aatttcaaaa
     4381 tgctggaata ccgccagcaa cagcagcaag aggattcatt cgataataac aatccaatgg
     4441 atattcaggc tgacgacttg ccattctaat aggaggtact gaatgggaat gaaggaatat
     4501 gctttggctt atcaaaaaaa aggattttct gtattgccca ttagtccaac tgggaagaag
     4561 ccgatgattg cttttgcgga taagccgcct atgactgccc aggaaattga agatttctgg
     4621 actcagtacc cagatagcaa tatcgctgtc cggacggata agtttttcgt cattgatatt
     4681 gacttacatg ggaaagctaa tggatttgag agtttggcca attgggaaca cttggatctt
     4741 atcactccaa ctctacaggc caaaacggcc agcggtggca aacatatctt ttatttcaaa
     4801 catccagatg tgtctatgac gcaaatgatt ggcttccttc cgggcgtcga cgtcaaagct
     4861 catcttaata actatgttct ggtggcaccg tctaaaactc ccaaaggtgt ttatgcctgg
     4921 gataaagaca agtcaaaaga ggatggcacc atggtcacag ctagtcgaaa gttagtcatg
     4981 gccatcaaac aagagtacaa caagaaaaat ccaggtagtg acctggataa tatctactat
     5041 caaattagca aaggtgctgg taagcggaac cggactacgg aactgtttga aatgattgtt
     5101 ttgggatttg gagaccaggg cgggcggaat gatactcttg caagatttgt cggtgggtta
     5161 ctgagtcggt cggtggatcc agaatgtatc ctgcggcttg cggaaacggc caataataat
     5221 tctgttgaac ccttgggcaa aagagaaatg agacggacaa tcgaatcgat gatcaaaaaa
     5281 cacatgaggg ggggtggcca caataggtga aattgttaat atttcaatca agcagttttc
     5341 acgacgaaaa aagaaaatcc tgagcgaaga aggtgaacag attgaagtag aatccattgt
     5401 ggcagacagc cctagaaatg tcttactggc gatgaaaagc gataacaagt tgaatgattt
     5461 tctccggcac aatgaattca ccggtgaaca tgagattgtg gaggatgtaa aactggacgc
     5521 cattcagctt cgacgtgggc agcttccatc tacttttgag tcatatctga gcgtctattt
     5581 ggaaaatcat ttcaaaacag tttttaaggc tggagcttta agagatggca ttgaagcttt
     5641 ttttgcagaa aaaacctaca atcctgttca ggaatacatg gagcacgctt atgaatcttg
     5701 ggatcacagg gagcggttag ctcaagtttt ccaaacgtgg ctaggtgctg aagacagtat
     5761 ctttgttcag cgtattgcgg tcatgttctt tgtcggtgca gtttcaaagg tgtttaaccc
     5821 ctgggtcaaa tttgactata cattggactt agtcggtggc caaggagcag gtaagaccac
     5881 cttcctgcag aaagttgcag tcgaatggta cactgattcg gcaaaagatt ttatggataa
     5941 ggataattat gaaatcatgc tgaagtctct gatcgtcaac gatgatgaga tggtggccag
     6001 cagaaagacc acttttgatg agctcaaggc atttgtaacc aaaactgaac tgtcgtttcg
     6061 taggtcttac ggtcgcagag ctgaaaaatt ccctaaaaac tttgtgattg ctaggacatc
     6121 gaacaaggtt gagtacctag gagacaaaac tggtgagcga cgctttctgc cagtgctggt
     6181 ggatgcagac cagcagttgg tcaaaccgtt tgatatgact gatcgggatg tgctccaact
     6241 ttggggtgag gcggtcgcta tttacaaaaa agggtttacg cttacttttg atgatgactt
     6301 cgaagacgaa ctggcggtct ataaggagcg gttcacttat aaagatgaag cggaatcaca
     6361 gatttacgat tatctggaca tgttagttcc tgatgagtgg gaagaaatgt cagtggttca
     6421 gcaacatcaa tatacctggg catactttaa taatggcagt tatcgtaatg agtcgggatt
     6481 tgtctatgaa ggtgttaaac tgcaagcgag tgtttccgcc aagcagattt tgaaaaacgt
     6541 atttgatatc gacagtgcaa gaggtgagag aattgctcgc aaaatcaagt tgattatgga
     6601 caatcatcaa gattgggaat accgaataaa gaagataaaa gggagaactg tcagggcata
     6661 ttttaagaaa aatatgcaaa atgaagtgat gtaacctttt aggctaaaaa aggctaaaaa
     6721 agcttaaaaa tggcgtttgg gttacatcag gttacatcat tgatgtaacc tgccgaaaat
     6781 ccattaataa caagggttta gggctatttt ttgagaaaaa ttcaaaaaaa gtgatgtaac
     6841 ctatctaaag ccttgatatg actggtttta tgaggtgtct attagtatgg ttacatcatt
     6901 tatataaaaa ctttaataag taaaaatagc aagtgctata aacgttgata ttatgggatt
     6961 cttgtttttt ataaatatat tttttgaaaa gtgatgtaac cttgtaacct cactaaaata
     7021 tgcaaaataa tgaataaaaa ggagagtaaa tgagttataa agttttagtt tattttgaca
     7081 atatgttgga cgaagaatat aagtttaaaa cagaaaaaga tgcatcgaaa tgccatgatc
     7141 aattgcgaag gaaataccaa ggtcagcgtt tatataaggt aaaaatggag gaggtggaag
     7201 aagaggtaat cataactaac ttcagggagg ttgatcatga ctaaagacga ctttttaaca
     7261 ggttttgtac ttatactttt agctgcttgc atttttgctg tgggatttgc gattgggcat
     7321 gattatagca gtgagcacta cgagcaaaaa atcacagatt tacaaataca gctggtaagc
     7381 acgcagcagc agcttaagca atctcgtgag caaaatcaga gccagactaa aaggattgcg
     7441 aatctgaccg ggaatggagg ataaaaaaca ctacatggaa ataaaatgtg gaaattgctt
     7501 agaattacta acagagttaa ctgatggatc aattgatatg gtgataacag acccgccata
     7561 taacatatca gtaaaaaata actttgctac aatggggcgg acaggtatag attttggtga
     7621 ttgggataaa ggtgcggact tattaagttg gattgatatt gcaagtcgaa aattaactaa
     7681 aaatggtgga atggtgatct ttaatgattg gaaaaattta ggagatattg caagacattg
     7741 cgaaaaaaca ggcttagcag taaaagatat tttccgttgg gtaaaagata accctatgcc
     7801 aagaaatcga gataggagat acattacaga tagcgagtac gggatatggg tcgtccgaaa
     7861 aaattccaag tgggtattta atcgtaaatc ggaaaaatat gataggccag aatatcgcta
     7921 tcctattgta tcaggagcag agaaaacaca gcaccctact caaaagccgg tagccctgat
     7981 gagggacatc attacgcgac acacaacaaa aagggctgtt gttttagacc cttttatggg
     8041 cagcggatca actggagtag cttgtctact gacggagaga gactttattg gatatgagct
     8101 aaataaagat tactttaata tcgcaaacaa aaggattgct gagttgactg ggaatggtgg
     8161 atgagatgtt aagagtattt gaagcttttg caggtattgg tacgcaacgc atggcattgc
     8221 gaaacctcgg gataccacac gaagtagtag ctattgccga gatcgacaaa tttgccatta
     8281 aaagttatga ggcaattcat ggcccagtaa ataatctagg tgatattagc aagattaatc
     8341 ctgacactat tcctgatcac gacttattta cttatagctt tccttgtcaa gacatttctg
     8401 tggcagggaa gcaagctggt cttgatattg atagcggtac acgctcagga ttgctctggg
     8461 aatgccaaaa agttatagtg gctaaaaaac cgaaatatct attaatggaa aatgtaaaaa
     8521 atctcgtagg caaaaagcat aagccaaatt ttgataaatg gcttgattgg ctagagagtc
     8581 aaggctacac gaatgactgg caagtgctaa atgcaaagga ttacggtgtc ccgcaaaata
     8641 gagagcgtgt gttttgtgtg tcgattttag gtgagcataa accttatatt ttcccagaaa
     8701 aacaggaatt gaccatcaga ctaaaggaca ttttggaaga tgatgttgat gaaaagtatt
     8761 atttaacaac aaacaaagca aatgaattat tggccacgat tgtccgagaa aatgatgttt
     8821 ctgaaagagt tgttgtagat agtacgataa aaaaaccaaa aataaaaaat gtaatgaacg
     8881 ctgtaatagg aagatatgat gcaggcatcc gaaatcaaca atcggttgga ggtgctgtca
     8941 ttgagcttat tgaataaaaa tgcaacaaaa aaaggctact tagtagccga tgatggggac
     9001 ggaatagata ctgcttatcc agatagcaaa acgaggaaag ggagagtgca aaaaaacatg
     9061 agccatacga taacgacaga tgatagtaag gcctttttga ttggcgcaag tcgtgggaga
     9121 gaccccgaaa acccaaacga taggtcagct ggaaaccaaa acctacaaca aagacttgaa
     9181 atcaacaaaa atggcacaag caatacaatt acaagtgtcc aaaaagataa ctatgcggtt
     9241 gaattcccag attaccgcat ccgcaagcta acaccgctag aatgttggcg gttgatgggg
     9301 tgtagtgatg aggattttga aaaagcacag tctgtcaata gcaatagtca gctttacaaa
     9361 caggcaggaa acgcaattgt ggttgatgtg ctagaggcaa tattaaagca attattttta
     9421 accgaggcgc aaaatgaaca ttgaagaagc gaagcaaaaa ttacataaca tggcatatag
     9481 agatttacaa actaagccgt atgatttgaa acttgctgat gttattcaga ttcttaatca
     9541 aattaaactc gacaaacctc aaccagaaat tccacagttt gtcgctgact acatagatga
     9601 tatgcacaaa aacgcacgta cattgagata cgcttttaaa tacatggaaa gtaacataaa
     9661 aatgcacaaa tggtgtgttt tcgaaaagca agaaacgttt gttaatgctt ttttatacgg
     9721 atatacaatt gaaaaagaga aactgtacac tgttgagata ccaaatccga aaaacggtat
     9781 tgcgcatagg cacataatgc tggttaagac aactgacgga agagtagttt tgtctgaagt
     9841 agtagactca cacatacatt tgagagatga tttaagactc accgagtcag aaatccgcaa
     9901 agacttcgat tgggcttgga gagaggagtt tcctaaagag gtgacggaat gatgaatgaa
     9961 agagaattaa ataaattgat gaattacgac aaaaagaaaa gtgatttaaa aaaacgcctg
    10021 attataggat ttaccctatt gccaatcagc atcgtattgt ctggatttgt tattaaatac
    10081 ggttggaata atattttgtc aacaattgat ggcgtcccac ctatcaattt accacaagcg
    10141 atagcaattg atgtgctagt aagttttatc attgccaaga caaacgcaga aggagatttt
    10201 gccacagaag ttggcagagc ttttatttcg ccgttaatga cgttgttatt gttttgggta
    10261 gtgactttgt ttatgtaatg tttagaggta acagatgact gaagaattag gagtgttgct
    10321 tgacaaggaa ggagttgaat acgtaaaaat ggtatttgat gatggctttg tctggacgat
    10381 acgcaaccca ctaaacgctg cgttgcttaa acgccaagat gcagagcagt tcccgcagtt
    10441 tacgtgggtg ccactgacag atttataacc ccacgcaatg gctctgtggg attacgtgcc
    10501 aggaaccacg ttgaaagcga cttagacacc ttcattttta tcagccttgc ggattgtcaa
    10561 aggttcgtaa ggtgtagacc gaaattaaac acagaaggat gtgatgacaa tctccttaca
    10621 cccaaaaaat ctaacgctgg ttaccggtca ccagctatta tccaaggcgc taatactgac
    10681 atcgtgcgcc tgtgtcaaaa taaaaaaagg aagagagggc ttttctccac aaaaaaagac
    10741 gtccatgcga acgcctcctt ggttatatct gttaacacca ttataccaca ctgagggggc
    10801 ttttatgacg ttttttcccg agattgatat ccaaaaaaca aaatccaatg ccaagcgtaa
    10861 attgaaagag tatccacgct ggcggcggat agctaacgat gtagatactc aaaaagttac
    10921 agctacttac tcatttgagc caaggcaacc tcatggagtc cctagcaagc ctgttgagag
    10981 actagcactt aatcgtgtat cagcggaaca ggaactggat gcgattgaga gagcggtcaa
    11041 cgggatattt gatccagagt atagattgat actgattgac aagtatttgc tcacatatcc
    11101 aaagactgat tgtgatattt atacaaaact tggttacgag aaaagtcagt actacaacat
    11161 gctagataat gctttaatgt ctttttctga actatacaaa gaggggatgt tgcttgtcga
    11221 aaaaatggaa aaaagctgga attaatatgg aataattatg tactttatat ataaatattc
    11281 atgttattat agtactatga aataacaaga agagataacc attttaccaa ctgactattt
    11341 atttagtcgc tgactttaac tacgatcaaa cttgttattt tatgtatgtg ggacgtgcgg
    11401 gttcgaatcc tgccgtctca atcagcgccc agaagaggcg cgaccccata cccctttaaa
    11461 ggcagacacg ttctgatgtg tgggttttta tgattaaccg caagttcaaa aacaagggtc
    11521 gcaaccttgc ttgtggttag tagggacaac ggttgtaagt cggttcgatt ccgactgttc
    11581 ctgtgctagt catcacatcg tgatggcttt ttattatgca aaaaagaacc actaagtggc
    11641 tcttatgctt gtagttttaa ttcaagtgcc tctgtgagga cttgcgagaa attgagattt
    11701 tcatcttcgg ctgctttgtt taaccactca gggatagtca cgttcttacg tactttttta
    11761 gagtggtatt ttttcatgta ggcaatcata tcgatgccga ttaaagcaat atcagaatca
    11821 cgatactgtt cttttaagtc ggaaacggag ctagcctttg gatagtcagt atagtcttca
    11881 agagcaaagc ctaagacttc gacagccatt tcgtaagctt cttgaaagtc tttaccttga
    11941 gtaattgctt caggtacatc tggaaatgta accatgatat agtctgtgtc ttgtgtgaat
    12001 gtagctggat agattaacat aatgattctc cttcgatcac tgtgagataa gcaaaccatc
    12061 tggcaagcgg attattttaa acccgcctgc tttagaatgg tatcttcaag gccttttccg
    12121 aggtctttgt tgtgtagagg aacaatggtt tgatgtccgt tattatctcg gaattttttg
    12181 tgacttccgt tttgactgac ttcatagaac ccattctttt ttagcagttt tatcatctgc
    12241 tttggggtca ttggcatatt gcttacctca ctttctatac ttatattata cacgcaataa
    12301 acatggttgt caataggtat gcgcaaaaaa tgcgtatttt tgttttctat tttttattat
    12361 ggaggttagg gtatgaggcc gcagaagtta acaattgcgg gtggcagacg aacgactgtt
    12421 gactacgatg ataggtcagc tgagtatcgt gactataatc gtaacagatg gaagtatgat
    12481 aggaagacta agcagtttta taactctaag atttggagag agacaagtaa gcaagtctta
    12541 ttgcaaagtg attatatctg tgcaatgtgt ggtggagaag caacgatgac tgatcacatt
    12601 gtctcagtta agaaagattg gaataaaaga ttagattgga ataacttgca agcaagttgt
    12661 aaagcttgta acgattgtaa agcaataaga gagagacgga aaacctaaac gtacataaaa
    12721 agtaacatac gcaatcattg ttcgggaaat accccgccta ttttttaacg gggctatatt
    12781 gttcggaaac ttaagaacgc gcccttttct gtgcaaaaaa atcccttttt gaaatttttg
    12841 aaactgtaaa gtttgtgtaa aggaggtctt atgggaagaa atttaaagct agttgaaacg
    12901 acaaaaaagc atcttacgaa agaagaaaaa atagtgcgag aaaccgcgca aaataaggcg
    12961 tctgacggtc ttaaaaagtt gcaaaagaca cctcctgaac actttaataa tgtagctaag
    13021 tacgagtata ggagaatcat agaagacctc caaaacctac ccctaagaaa tctcgataga
    13081 gggctattag agttatattg cacatggtat gctatctaca aagaaacaag tagaaaacta
    13141 gatgaggttg gttattttac gaatgatcca gacaaaggca ttattcctag tccgcttatt
    13201 ttaacattgg aaaaagccac tgcgaatatt agaagtagtg ccagtcaatt aggactaacg
    13261 gtagatagtc gcatgaagat gtttattccg aaggaagaag aaaaacctaa gagtatattt
    13321 gataaatttg gaggatagag agaaaggggg tcatgacaat agaatacgat tattcagcaa
    13381 tcggcgacat ctataaagat gacgcttttt attatgcaaa aaaggtcgtt gatgaagaga
    13441 ttaaagcaag taagaaggtc tttaaagctt gtctaagaca tttgaatgac cttaaaaaaa
    13501 tagatgatga taattttaaa tttatctatt taccaaaaaa agcaattgac cccataattt
    13561 ttattgagct attgccagac gttaagacgg gaaagcctta tcctttagcg atgtttcaga
    13621 agtttattat cgggaattta tacggatggc gaaagaaaac agatcattcc ttaagacgct
    13681 ttagaaaagc tatgatttcg gttgctcgta aaaatggcaa aacaattctg atagctggta
    13741 tcttgcttta tgaatttttg tttgggcata atccatctat gagtagacaa ttgttttgta
    13801 cagctaatga ccgtacacag gctaaaattg cttgggacat ggcaaagaag caactctcat
    13861 ctttaagagc aaaggacgct gatgtcagaa aagccacgaa aattgttcgt gatgagctga
    13921 aaaacttaca tgatgaatct tatattaggg ctcttagtcg agatactggg gcagtcgatg
    13981 ggttcgagcc ttacgttggc gttttagatg agtttgcggc atcaaagaca aacgaaatgt
    14041 tagagctttt agaatccggt caaggtcagc ttgataatcc gtttatcttg attatctcaa
    14101 cagctggtat ggatttgaat gtccccatgc acacaattga gtatccgtac atcactaaaa
    14161 ttttagacga agaaattgta gatgatggct attttggata tgtcgcagag caagacaacg
    14221 aaggtgaaat taaagatgaa tcaaattgga taaaatcaaa tccaatcctc gaggttgaag
    14281 ctttgcacga taagctaatg gattacctga gaacgcgtcg tagagtgtct cttgaaacag
    14341 gtgaaattaa caaggtactt atcaaaaact ttaacatgtg gcggcagtcg agtgaggaat
    14401 catatattga taagcaatct tgggaacttg ctcgtattga taaacccgac acacataaac
    14461 gaagggtctg gctaggtgtg gacgtcggtc gtgttagtga cttatttgct attacaccag
    14521 ttattatgat ggacgatttt tggtatattg acagtttttc ttttgttgcg acaaagtatg
    14581 ggttaacggc taaagaaaag cgtgatggtg tgtcttacag taatttagaa cgtcaaggct
    14641 attgcgagat aacaacatta gaaagtgggg ttattgatga tgagagagtt ttagaaaaaa
    14701 tagaggagat ggtctattcg aatgactggg aagttaacgg aatctgtttt gacccttacc
    14761 aatttggaac gctgcttacg atgattgaga aaaggcaccc agaatggcct ctcatagagg
    14821 tttcgcaaac gacaatggtt ttgaacatgc caacaaagca atttcgtgat gatctcaaga
    14881 atggcaaaat aaagcactct ggcaatccat tgctaacaat ggctgttaat aacgcttata
    14941 tcaagactga taacaatggc atgaggattg ataagaataa gaatagcaat aagatagacc
    15001 ctctggacgc tgctttagac gggtatgcag tttgttactt agagccattt gacggctctg
    15061 gttactggac aagtgagaaa attttaggag gagagacact gttttgattg gttttatttt
    15121 aaaaaacata catacattaa tcttgttagc tggactaggt ttattgatgt atgggttgtt
    15181 tttgtttggt gataaagttg gttttatcgc tagtggtctt attttaattt ttttagctat
    15241 ctatgtagat agcgtaggag gaaaacatga ataaacgcat taagaaaaaa cgtaaattgg
    15301 aaacagcggt tgtgatgctt gttgcagaaa atgctatgca agctgaagca ctcaggaatc
    15361 aaaacagaca aattgcagag ctgagatcga ttatacaaca aaacgcccaa gcgacaaata
    15421 gagagtttgc agcagttaaa tcagcgacgc tagacaacca agcagccatt aagaaaattg
    15481 gggatgaggt ttattatatc aagcaaaatt ataagcgcaa gtggcggaaa tagatgttaa
    15541 tggtttagaa aggaggtgag aaatcgatga gtttttttca acctttgggc agttcaaagg
    15601 tgtcctatga tgactatgta tcatctgttt tagctggcga tgtctcccaa aaatacttag
    15661 gagtgtcggc tttgaagaat agcgatattt taacagcaac gtctattata gctggggata
    15721 ttgctaggtt tccgcttgtt aaaaaggatg ttaatgggga cattatccat gatgaggata
    15781 ttaattatct tttaaatgtt aaatccacaa aaaatgcgag cgctaggacc tggaagtttg
    15841 ctatggcagt aaatgccatt ttgactggta attctttttc gcgtattttg agagatccaa
    15901 agactaacca agctttgcaa ttccaatttt acaggccgtc agaaacgact gttgaggaga
    15961 cagataacca cgagatagtt tatacgttta ctgatatgtt gacagcaaaa caggttaaat
    16021 gttttgccca tgacgttatc cactggaagt tttttagtca cgatacaatt ttgggaaggt
    16081 ccccgctact gtctttaggt gatgagattg atttgcaaac cggcggcatc aataccttaa
    16141 ttaaattctt caaagatggt ttttctagtg gcatcttaaa aatgaaaggt gctcatataa
    16201 gcggtgaagc acgtaagaga gccagagttg aatttgaaaa aatgcgcgag ggtgcaattg
    16261 gtggtagtcc tttagtattc gatgatacgc aagaatacac gccgcttgaa atcgatacta
    16321 acgtattgca attaattaca agtaacaatt tttcaacggc gcaaatcgca aaagctttgc
    16381 gggttcccag ctacaagctt ggtgttaata gtccaaatca atctgttgcc cagttgatgg
    16441 aagattatgt cacgaatgat ttgccatttt attttgatgc tatcacaagt gagttaggac
    16501 ttaagacgct aagtgataag gataggcgtt tgtatcgtat cgagtttgat acacgaagcg
    16561 tcacaggtcg caatgttgat gagattgtca aattggttaa taaccaaatc ttgacgccta
    16621 accaaggcct cgtagagctt ggtaagcaaa aatcaacaga tccaaacatg gataggtacc
    16681 agtctagtct aaactacgtc tttttagaca aaaaagaaga atatcaagac aaggttggta
    16741 tcaaagggaa aggaggtgag gtaaatgcca aagaggataa atcttaaagg accactaatt
    16801 gcaaataact ctcaagaagt ttacgactat tacggaatgg aagcagcaag tgctaaaagt
    16861 atcattgagc aatttcctga agataatagc gatattgttt tggaagttaa ttcaaacggt
    16921 ggacttgtga cagttgggag tgaaatctat accgctttac gaaattacaa aggaaaagta
    16981 actgcagaaa ttactggcat ggctgcaagt gcagcatctg tggctgttat gggtgcggat
    17041 aaggttgtca tgagtcctac agctcaaatg atggtgcata aagcactctt taaatgggtg
    17101 tctggtaata gtgatgacct agacaaagct tctaatgcct taaaatcaag tgataaagct
    17161 attgtgagtg cctatgtcgc aaaaacaggg ttatcagaag atgcaatcat ggatttaatg
    17221 cgaaatgaaa cgtttatgtc cgctcaagat gccgtagaaa aaggttttgc ggacgaagtt
    17281 atgtcttttg aagcagttgc tagcattgat aattccatgt tgccgcaagc tgttattgat
    17341 gactattaca gaagtaggaa caaacgaaaa caagagatta gcaacatgtt actagaaatt
    17401 gaaaaagaag aaattttacg agggctataa gctctttttt tattggagga atttatgttc
    17461 gaagaaaaaa tcaaagaaat taaagcgaat atcgctaatt taaaccaagc tattgctact
    17521 aaaacaacag aagtaaaaaa tgctttggaa tcagatgacc ttgaaactgc tcgctcaatt
    17581 aaagcagaaa ttgaagaagc taaagcaaac ctagcagaag cagaaaatga cttgaaattg
    17641 tatgaagcta gcattgaaaa aggcggtgca gaaaatactg gaggaaaaga agtgccacaa
    17701 gaaactaaaa cataccgcga aagcgttaac gaatttattc gttcaaaagg aacagtaact
    17761 aatgaagctt tgcgttttga aggaaaagat gaagttctta ttccgcttaa tcagacaaca
    17821 ccagtcgctc ctgacacaga tggaattaaa aagacagacg tgaaacctgt ttctagcgaa
    17881 gaaattctat acacaccagc tcgtgaagtt aagacagttg ttgatttgaa acaatttact
    17941 agcatccacc cagctaagaa agcatctggt aaatggccgg tattgcaacg tgctacagaa
    18001 aaaatggtaa gcgttgaaga attggaaaaa aatccaaaac taggcaaacc acaatttaaa
    18061 aacgtggagt gggaagttaa aacttatcgt ggagctatcc cgttatccca agagtcaatt
    18121 gatgatgcag atgtagattt ggttggtatt gttgctgaaa caatcggtca aatgaaagtt
    18181 aatacaacta atgatgcaat tgctaaagtc ctaaaaacat ttgaggctaa agctggtgtc
    18241 aaaacattag atgacatcaa aaaaatccta aatgtagatt tagatccagc ttacaatgtg
    18301 tcatttattg tatctcaaag cttttaccag tccatggata ctttaaaaga cgaaaatggc
    18361 cgttacctac ttcaagattc aatcacttct gcgtctggca aagtgtttct tggaaaaccg
    18421 gtatttgtcc tatctgatga cgtaattggt aaagactcag cttttgtcgg agattttaag
    18481 cgcggcgtgt tatttgctga tcgtaaagat ttagggcttc gttgggcaga taacgaaatt
    18541 tacggtcaat acttgcaagc tgtccttcgc tttggtgtcg ctaaggtaga tgacaaagct
    18601 ggatactatg tgacattcaa accagaacaa ttgccctcat aaggccactg aagaagtggc
    18661 gaaaccaact agcaaaagca ctgtcgagga gattaagcgc tatttaacaa gcaagggaat
    18721 tgactttaat gggaaaacat taaaatctga tttattaaaa cttgcaggcg ttgaagaggt
    18781 atagctatgg ctgtatcaaa agagttatta gacagtgtaa aactctattg taaaattgac
    18841 tttgattttg atgacgacat catcaaagaa atgattgaat ctgctcaaga acaaatctgt
    18901 tttgcaatag aagacggttc tactcctgaa aagttcaaag gtcacgctaa atttaattta
    18961 gctgtcaaaa agcaagtcaa ggaagagtat gaccatcgcg gtttgtctgc ggatagtttt
    19021 cgctatccgt tggcaaatgg tgttttaaac attatccatc aattgcgatt gagaggtgat
    19081 gattcgtgat tacacgcaag atgaacgtca ggataacgat ttttagccaa tcaggcgggc
    19141 aaaatgaaga tggtgaagta gtatctgctg tcagaaagga cttgtatact tgttgggcag
    19201 aagtgctaaa aacgcagttg agagatttta attatcaatc aaagtatcaa aacgctagca
    19261 atttgccaac aaataaggat actaaggttt ttttaattag gtataaccct gaattatcta
    19321 tagataacac gatgtttgtt gagtttggca agcgcattta taagatagat aaaatcgaat
    19381 ctgacgaatc tggcaaagat attatcatga taagtggagt aagcatgtca tgacaaaagg
    19441 tttagatgaa atattggcta atctgacaaa gcttgaagta aaagcaccaa aaaccgcaaa
    19501 agcagcagta actgaagttg ccaaagaatt tgaaaaagca cttaaagcaa atacccctgt
    19561 ttatgagatt gaaacagatg agcggctaca ggaagatacc gttatcagtg gttttaaagg
    19621 agctaatgtt ggaattgtat ccaaggaaat tggctatggc aaagcgactg gttggcgtgc
    19681 gcactatcct aacgatggga ccatttacca acgcggacaa gactttaagg aaaaaaccat
    19741 caatcagatg acaccaaaag ctaaacaaat ctacgcagca aaagttaagg agggactagg
    19801 actttgattg ctgaaacagc agcttataaa ttattaagta acgataagac gctaaatgag
    19861 ttgttggata ggctcagagg cggtcctttt aaaaatgggt ttaagcaagg catatttact
    19921 tatgatattc cagataaccc agttgacttg cgtaaggtag atttagcgcc ttttatgcga
    19981 atcaacacaa cattagacgg tcctgctgat tatgcagatg atgagatact gtgtaacgag
    20041 caacggatca ccatcaattt ttggtgcaaa acagcttctg aagctgacca aattagcaaa
    20101 tgtatagatg atattttaaa aaaaggcggt tttgaaagat acaccgcaaa cgaaaaacca
    20161 agatataaag atagcgatat tgacttactg ataaatgtaa ggaaataccg ctattttgat
    20221 ttttattaaa agaaagagga aaaaatggga aaagtaaaat ttggactacg tgacttccaa
    20281 tacgcagtac tcggagatga tgatcaatta aaaacaaaaa cgggaggtat caaatcacta
    20341 cctggcatga aatcagcaaa gcttgatatt acaaacgaat tagtgacggt agctgctgat
    20401 gatggtccat acgtagtttt atctggaggt attacagaaa caaaacttga aatcgaggtg
    20461 ttagacttaa catctgacgc acgaaaagac ttcttcggaa ttaaggaaga agacggaatc
    20521 gaaaaataca ataaggagct gacccctaac gatgttgctt gtatgttccg aacaagcgat
    20581 gaaaacggga aagccatctg gattggattg ctaaaaggta agtttaacat tccgggtatg
    20641 gaaatgcaga ctaaagaggg agcgccagac cctaaatctg atactgtaac aggcaacttt
    20701 gtgtctcgtg gaaaagaagg agatgttatt gttatcggtc gcgaaagtgc tagtggtttt
    20761 aaattagaga agtttaaaga atttgtgttt gctggtgcga cagatattaa aaaaggcgaa
    20821 aacttcgaaa tgtaacaatc aggttggatt taaaatccaa ccttttattt ttgataagga
    20881 gtagatatgt acgaaattac cttaaaaaaa ggtggtgtag ataaagtttt ttcaaaggac
    20941 tttattaacg ttgaggataa tttgttggct gttgagcatc aagttagaca aagcgctgtg
    21001 tttagcgatg agaaaagacg cttagattct aaagcgcata gaaaacttaa cgaatcttac
    21061 ttgcaaatgt ttgttgatat gtacgcaggt caatttacag tcgatgattt aaagcaatct
    21121 gacatgagtg ttttaaatac acttaatgac ctgtacattg cagcactcgg tggagagcaa
    21181 gaggaagacg aaagcgaaaa aaaggaacaa taaccccaca agaggctaaa gaaaacttac
    21241 tcttgtggat acagagcctt ttgaaaaacg gttataccat tttagatatt aaaaaaatgc
    21301 gcttatctga tattgaattg atggtacaag cgctagaaat tgaaactgtc gaaaaagaag
    21361 aagtgattga aacgaccttg gataaggcat tcccattcct tttcggctag aaaggaggat
    21421 aaatggggaa tataggtgat ttagtagcaa cggctacact agacatatca ccatttatgt
    21481 caaacacaag aaacctaaaa acctacatga aaggcttaga taactcgtta aaagcagttg
    21541 aaaagagctt tcaagggcat ggcgggcgga tcaaaggtct taaagcggtc tatgctgaaa
    21601 caggtagtgc attaaaaggt taccaagaat tactaaaaac tcagtcgcaa aaatatagcg
    21661 acctaaaaaa agagataggt gatgttaata acgctactgc tgagcaaaag caaaaattga
    21721 ttggcgctaa atcagccatg ttggagactg ctgcgaaagt cacagaattg caaaacagat
    21781 tacgatcgtt agccactgaa actagcgttt ttacaagatt tggtaaagct gctgaaagaa
    21841 tcggcgggaa gatgaagtca ttcggcgatt cggtagctgg agttgatgct gcatttacaa
    21901 gaggagtcac cgctccgatt gtagcgggcg ctggttatgc tattaaagca gctgttgact
    21961 atgaaactgc atttgctggt gttaaaaaga cagttgatga gacggcgaca gtatcttatg
    22021 cgaagctatc acagggtatt agacaaatgg ccaaagagtt gccagccagt gctgttgaaa
    22081 tcgctcatgt cgcggaggcg gcaggtcaat taggagttaa gacaggagat attcttagtt
    22141 tctctcgtac aatgatttat ttaggagagt ccaccaattt atcggcagaa gaagcggcga
    22201 cgtctattgc taaaattgca aacattacag gtctggcttc atcggagtat tctcgctttg
    22261 gtagtgctgt tgtcgcgttg ggtaataact tcgcaacaac tgaaagagac atcgtagcga
    22321 tgactaatcg cattgctgcg tctggtaagc ttgcgggatt aaccaatcaa gagatgttag
    22381 ctttagcaac agcaatgtca agcgttggta tagaggcaga agctggtggt acagcaatga
    22441 ctcaatcatt gtcagctatt gaacgtgcag ttgcatctgg aggagataat ttaaataaat
    22501 ttgctcaaat tgccaatatg tcatctgctg atttcgcgag agcatggaaa gagaagccaa
    22561 ttgttgcatt gcaagagttt attaaggggc ttggccagct tgataaaaaa ggtgaaagtg
    22621 ctacaaaagt gcttgacgac ctcggattaa gcggtatccg ccagtctaac atgttgaaat
    22681 ctttaggatt agcatctgag actttaggca aggctctaga tacctcaaac aaagcttggc
    22741 aagaaaacac tgctttaact gacgaagcta ataaacgcta tgagacaaca gagtctaagc
    22801 taaaaatgct taagaatgaa gttaatgatg tagctattga atttggtggc cctttggttg
    22861 acgctctaag aaatgggctc gaagcaggaa aaccaattat tcaaatggca gcagatttag
    22921 ctaagcaatt taactcgctt gacaaagagc aacaacaaca aattgttaag tgggggctta
    22981 ttgcagccgc agctggtcca gctttatcta tctttggtaa aggcgttggc attatcggag
    23041 gaaccattca agctatgggc aaaatgagtc gagggttagg cactttatca ggctggttga
    23101 ggacattcag aactggagca gtagcagcta gtgcaggagc cgaagctgcc acagcttcta
    23161 tgggcggaat ggctggcgcg gttgccttat taagtaatcc tgtaacttgg ggtgtgctgt
    23221 taggtggtgc agccattgtg ggtataggtt taattgctga tagcatgtat aaagcccaaa
    23281 aacgcacaga agagtgggga attaaagtga gtcaagtgca agccaatgaa ttgcaaagat
    23341 ttaaaaacaa agttgacgaa gctaacctcg caatgacaac atttggagtc aggagtgcta
    23401 ataatctcga taaaatcaag acatctttta aagcactggc agacgaaata gaggctttac
    23461 aaaacaaaaa acttaagaag gatctaaaac tagccgaaaa gttaggtctt agtcaagaga
    23521 caatcgagga gattaggcgt caagctgacc aaactgtggc aacagttaga ggtatgtctg
    23581 acaaagttgt agacatttac cgaagagcca aagaagaaag aagaagtttg actgaagaag
    23641 aaaagactgt tgtcactaaa aatttgaatg acatgatcca gactgagtta tctttgatga
    23701 actactctaa aaaagaaaag atcgccattt tgaaggcgat gaatggagag attgaaacgc
    23761 ttaattatga gcaacttaaa aaagctcaag aagttgctca aaagatgata gagagcgaaa
    23821 acaagactta taaaaagaga cgaagtaatc tcaaagaaat gtatgacaat atcaaaggag
    23881 actctgaaac tgctgtgaga gccagagagg agattcacag acagctggag accttggaag
    23941 atagtcatac agcaaaaatg gagagtttag gagaaagata cttaaaaatt cgtaaaaaac
    24001 ttctggtaga cccagcttta gatccacgag ttaagcaggc tatgattgat agcttagaca
    24061 aggaatttga aaaattagga ttatctttcg aaaagttatc taaaaggagt gaagaggcta
    24121 gctctaagac caaaataagc atgcaagaca tgacaagctc attcagagca tcgataggcg
    24181 aagccattag ttcattgcaa gggtgggaca atcttacgcc gcaggaaaaa caattgttga
    24241 tagatgggaa taaggctgtc agtgagatcc taaatagtaa aactttactt gagcaatggc
    24301 aagcgctgac ccctcagcaa aaagaactgt tagctaaaaa tctaactcaa gacccaacgt
    24361 tatcagctca acaagcaatc gataatgtta agcagcgagt gccagctgat gttaaagcct
    24421 cggacaagac tgctccagat gtcgcttctg ccgatagagc cgttaacagg cctaagcaaa
    24481 aaggtccagc tattattaga gcacaggata atgctagtag tgttgctagt ggagttattg
    24541 ggtggctaaa tagtatacct cgtacagtga catcgacaat aactacaatt gttcgtaaaa
    24601 taaccggcca taagacggga actgattacc accctggcgg tttagcgatg gttaatgacc
    24661 aaaaaggtcc tttgtatagg gaattgatca ctttaccgac gggagaatcc tttatcccgg
    24721 aaggaagaaa tgtcattctt cctttgccaa gggggtcaaa agttcttaga gcaagtcgta
    24781 caaaacaatt attctcgcat tatgcaaacg gaataggttt taatgatacc aaaatcgcta
    24841 gcttaacaac tcgtcttaaa tctgtgcaag ataaaggaca agtgattgtc aataccgatc
    24901 ctcaacttgc ggagttgatt aaactactta aagatagaga taacagaaat gtcacaaaca
    24961 actacacact taacgctaca aacaggagta actctgatga tatgtttaat caagaaaaca
    25021 tgagacgtct cctaagagaa cttgcatact atacaaatgg agagaaaggg aggttggctt
    25081 aatgcgatac attgaattta atggtaagaa aagtgatagc tttggtcttt tgctagagcg
    25141 tgaacgatct attaagtcaa cgagtaacga tgttgattta atagaagtcg atggacgcga
    25201 cggtgtactc ttaaaagaca atggtcgttt gaaagctatt gagcaagact ttcctttttc
    25261 tttggttggt gacgtggctg tcaatcagca aaaaataagt gaatggttac atgtcaaggg
    25321 ttggcacgac ttagctttgt cttgggacaa ggactatatc tatcgggcta gtgttgtcaa
    25381 tctttttgaa atagacgaga tacttaagca atttggtaga ttaaaggtta atttcttaat
    25441 ccaccctatc aaatacctaa aaactggtaa gcaagaggtg tctctcgtta atggtggcac
    25501 tctacaaaac cttggtaatg tgcagtctaa acctatctta aaaatcaaag ggacaggcaa
    25561 cggtgtttta accattaatg gttttgagac gggcctcgaa aacgtccaag gagagctcat
    25621 catagatatg gagaggcacc ttgtctataa agatatcctg tctgcttggg ataacattgt
    25681 gcggacagaa cgccaccgca tgccactatt tgatattggt caaaacaaaa tctcatggac
    25741 tggtaacttt actatcaccg cagtgccaaa ctggggggtt aaagtatgat accagtttta
    25801 tacgaggcca aagaaaccaa atttaggact tttggccttg gtgagatcgc agacgcttat
    25861 gaggtaagag ttactcgtga gcgcaacggt aattactcgc tatatatcaa atatccactt
    25921 gatggtgttt ttgcctcggt ctttaaggag gagcttaaga ttaagtctga tgccggccga
    25981 aggacaaaat ggcaaacttt tgagatcaat cgggtgttgc gaaacagtaa agaccacatc
    26041 gagatttttg caaggcatat ctcaatgcgc acacaggaca tcgctttaaa accatttgtg
    26101 agcgggtcta gcattgacgc agagtcggca ctggaggttt ggcgggataa tcttgtcggt
    26161 gatgatacct ttgatgttaa aagcgacatt ttaacactag gcagctttaa ctgggaagtt
    26221 gacaagatag gcaatgcaag aggcgctctc gggggtgttg ctggctctat cttagatgtt
    26281 tacggtggtg agtacgagtt tgacaatcgc acaatcatct tacataaaca aatggggcgt
    26341 aaggccccta cggttttgga gtatggccgc aatatcgtca gcgtggaaga ggagcgtttg
    26401 cttgatggca attatacctc aatctatcct tacgtaagat atacgccaca accaaagccg
    26461 caagaggaag cctctggtaa gccgcacatc ggtgagcagg agcagcccga agaacaactg
    26521 gtgacgctgc ctgaatttat cctagatggt cagtatcttg acttatatgc ccaacgcaga
    26581 atacagatgg ttgatttatc tagtcatttt aatgatgaca aaaaagagcc gacagtcgaa
    26641 gaaatcagaa agctggctca gaaatatctt aaagataaca atgttggcgc acctaaaatc
    26701 agtatagagg ttgattatat cgacctgtca cagacgcttg actatcaaga ttttagagtt
    26761 atggaggagg tcgagctttg cgatattgta ccgctttact atccaaagtt tggtatcaca
    26821 accgagaccg aaaaagtcgt tgagattgtc tatgacgtct atacagatag caatcacaca
    26881 ataaagcttg gcacgattgg ccaatctatc tctaagagtc tgacaggtgg tgttacgcag
    26941 cggattgaga cgctggaaaa caaccaaaag gttattacta ataatcaaca gcaatttgag
    27001 cttaatttac ccaaatacct caacgatcta aacggtacca agatatggta cgaaaaacca
    27061 gatgacaacg ttgagcacaa gataggcgat ttttggtttg agaaaaacgg taaatatcag
    27121 cgtacctggg tttgggacgg gaatcaatgg gtaaaaatca ttgatactga ggatttaaat
    27181 cctaatcagc gagcttttga tgaggctatg gccgagattg aaaagctaaa gcagcaccag
    27241 cgagaactcg acgaacgcaa ccaaaaagag ctcgaagagt ttagagaaac cctcaaaaat
    27301 ctgtcgctgc ccgaggaagc catcaaaaag ataacagagg ctatcaaagt tgatgatata
    27361 ccgtcaatta aacagtcgtt tgacgacctc aaaaacaaag tcagtgagac gagcgagacc
    27421 gcacgattaa acgctgagat tatcgggaca gatggcaaga cccgctacaa caaaaactta
    27481 ttggttggcg accctaatcg tgtcaaaaaa attgatgagg attttatcga ggtagaagcc
    27541 aacgatggtg gctttagacg cggtgagact tacaccatca gctttagcca aacttgcgag
    27601 ctgctcaaaa aagtggctat cacgttgacg caagctaata ataagggtgt taaattagtg
    27661 ttgataccga ctaaagctaa gatggaggcg cagaccttta atctaagtaa agataaggag
    27721 gtcatcagcg tctatccttt gagctacagg gctgttttga caggtgactg gtataaatct
    27781 aagcagattg agttaaatgc ggcagaggtc caaaatttgg ctctggagat gtcttataga
    27841 gacgtagttg atagcaataa tgctagtttg attttggatt ggtccccaaa tccagatgtt
    27901 atttttgatg gaaatggagg tagttaatgt cagagactat atcagctata gttgtgcata
    27961 aaagcatgac aaaaaacgag tgggagtcta gtgacatcat tttgccacaa ggccagctcg
    28021 tctatgagtc tgacacaggc catagtaaat ttggcgacgg taaaaataga tatgcagatt
    28081 tgatctatca aggtgggcca cctggaccac aaggtccaca aggactaagt ggcgaccgcg
    28141 gtcccatagg acaaacgggt ccacaaggta aacaaggtgt cagtgtccaa agtgcatcag
    28201 tagatagtga gggctattta actgttttgt tagataacgg acagtccttt aaatctgata
    28261 gcagcttaaa aggatctaaa ggagatactg gtcctaaagg tgctgacggt aaaatgactt
    28321 ttgagcaatt gacgccagag caaaagcaac aactaaaagg cgacaaaggt gatccaggtc
    28381 ctaaagggga cattggtcct agaggcgcaa cggggcccca aggtcctaaa ggagagccag
    28441 ggataaatgg tatggacggt ccaagaggtg caacaggtcc ccgaggactg caaggcccac
    28501 taggaaaaga tgcggttttg cccgacgacg ttgttagacg tggtgagcta gcagcttatc
    28561 tgctacggtc ggaatacaaa gctaaaggct caggatcagg tctaagctat aaagttgtca
    28621 cccagtctga gtacgatgat ctgtatgatt acaacgacaa cgagttgatc ctcgtgacgg
    28681 agggttgaca tggcatataa gctttatact aaggctgatg ttggtgacaa catgttgctt
    28741 gtcgctggcc gccctctgcc cgatgacaca aagcgcctaa aaatccagcg tgagacgtta
    28801 gatgtgttaa ctattaccca ttatggctct tacgacatgg tgcacctcaa gtcgacagtc
    28861 aaaaaggcgt atagcaaaaa tacagttgtt actcctgtat ctgcagctgc tagcaagccc
    28921 aaagctaagc caaagcacgt tttaaacttt gctaaggcta ataaggttta tataggcagc
    28981 actcgtgtaa tagcagtgta tttgggtgat cgcctgattt ggtctgacaa acatagcagc
    29041 gggaccaaaa ctgtctcggt tgtggggagt cttgatatca gacaatcaca aaaaatgctg
    29101 tatttgtact taatagcgcc agacgtcgca gatgttaaaa gcaagcgcat taaatcgata
    29161 gcgatcaatg gcgttaaact gtcaagcact gcacaaatca gctttgaggg cagcagctat
    29221 tattaccttg tgacaatcaa gcaagttgct aacatcaaag agatcaaaaa tatagcgtca
    29281 aaaaacaaaa tcacgctaga gttttaggag gtaacaattg agcagagacc caacaataac
    29341 attagacgag tcaaacctcg tcataggaca agatggccgc atgcactaca cgtttgtagc
    29401 gcaagatgat aaccaaaaag tcagactggc tagtaactgt ctaggcacag cgcattttaa
    29461 ccagctgatg attgagcgag gaggccaagc gacggactac gttgcgcccg ttgttgttga
    29521 gggcagcggc aagccaacgg gcttatttaa agatcttaaa gagcttagtc ttgagctcac
    29581 agatactgct aattcccagt tgtggtcaaa aatcaagctg acgacaaacg gcatgttacg
    29641 tgagtatcat cgtgatcata ttaaaacaga aattattgag agcgccgatg gtattgccaa
    29701 gcggattgcc gatgacactg gccaaaagct ggcactaatc aatgagacca tcaacggtat
    29761 cagacgcgag taccaagacg cagatagaca gctatccgcg agctaccaag caggcattga
    29821 tggcctaaaa actcaactgg ccaatgataa aatcggtcta caagctgaga ttaagctgtc
    29881 agctcaaggc ttgtcacaaa aatacgatga ccagatacgg cagctatact ctaaaatcac
    29941 cacaacctca tcaggtacca cagaggccta cgaaaacaag cttgagggct tgcgggcaga
    30001 gtttacaaga tctaaccaag gcctgcgcac tgagttagag tcgcagatta gcgggttaag
    30061 gtctgtgcag cagtcaactg ccagccaaat ctcacaagag atcaaggacc ggacaggcgc
    30121 tgtcagtcgg gtgcaacagg acttaaatag ctatcaacgt cgattagcaa gtgctgaggg
    30181 caattacagc agtcttttgc agacagttaa aggtctacaa tcaactgtta gcgatcccaa
    30241 aggtaaaatc caatcac
//
LOCUS       DARYLJ010000028        29896 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYLJ010000028 DARYLJ010000000
VERSION     DARYLJ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29896
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            336..662
                     /locus_tag="TU746_001139"
     CDS             336..662
                     /locus_tag="TU746_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL0891489.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
     gene            649..1074
                     /locus_tag="TU746_001140"
     CDS             649..1074
                     /locus_tag="TU746_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891490.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            1093..2148
                     /locus_tag="TU746_001141"
     CDS             1093..2148
                     /locus_tag="TU746_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL0891491.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(2252..4534)
                     /locus_tag="TU746_001142"
     CDS             complement(2252..4534)
                     /locus_tag="TU746_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL0891492.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            4666..5199
                     /locus_tag="TU746_001143"
     CDS             4666..5199
                     /locus_tag="TU746_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0891493.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TU746_001144"
     CDS             complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TU746_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL0891494.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(6541..6813)
                     /locus_tag="TU746_001145"
     CDS             complement(6541..6813)
                     /locus_tag="TU746_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL0891495.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TU746_001146"
     CDS             complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TU746_001146"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL0891496.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TU746_001147"
     CDS             complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TU746_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL0891497.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            complement(8676..10652)
                     /locus_tag="TU746_001148"
     CDS             complement(8676..10652)
                     /locus_tag="TU746_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL0891498.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TU746_001149"
     CDS             complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TU746_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL0891499.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            complement(12641..13105)
                     /locus_tag="TU746_001150"
     CDS             complement(12641..13105)
                     /locus_tag="TU746_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL0891500.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TU746_001151"
     CDS             complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TU746_001151"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL0891501.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            14715..15386
                     /gene="sdaAB"
                     /locus_tag="TU746_001152"
     CDS             14715..15386
                     /gene="sdaAB"
                     /locus_tag="TU746_001152"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL0891502.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            15398..16270
                     /gene="sdaAA"
                     /locus_tag="TU746_001153"
     CDS             15398..16270
                     /gene="sdaAA"
                     /locus_tag="TU746_001153"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL0891503.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            16304..16939
                     /locus_tag="TU746_001154"
     CDS             16304..16939
                     /locus_tag="TU746_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL0891504.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(17000..17611)
                     /locus_tag="TU746_001155"
     CDS             complement(17000..17611)
                     /locus_tag="TU746_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL0891505.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(17867..18676)
                     /locus_tag="TU746_001156"
     CDS             complement(17867..18676)
                     /locus_tag="TU746_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0891506.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(18669..19511)
                     /locus_tag="TU746_001157"
     CDS             complement(18669..19511)
                     /locus_tag="TU746_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL0891507.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(19487..20326)
                     /locus_tag="TU746_001158"
     CDS             complement(19487..20326)
                     /locus_tag="TU746_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL0891508.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TU746_001159"
     CDS             complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TU746_001159"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL0891509.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(20884..21888)
                     /locus_tag="TU746_001160"
     CDS             complement(20884..21888)
                     /locus_tag="TU746_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0891510.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(21938..23221)
                     /locus_tag="TU746_001161"
     CDS             complement(21938..23221)
                     /locus_tag="TU746_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0891511.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(23223..24467)
                     /locus_tag="TU746_001162"
     CDS             complement(23223..24467)
                     /locus_tag="TU746_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0891512.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            24682..25095
                     /gene="yaaA"
                     /locus_tag="TU746_001163"
     CDS             24682..25095
                     /gene="yaaA"
                     /locus_tag="TU746_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL0891513.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            25097..26206
                     /gene="recF"
                     /locus_tag="TU746_001164"
     CDS             25097..26206
                     /gene="recF"
                     /locus_tag="TU746_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL0891514.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(26271..27134)
                     /locus_tag="TU746_001165"
     CDS             complement(26271..27134)
                     /locus_tag="TU746_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL0891515.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(27305..29734)
                     /locus_tag="TU746_001166"
     CDS             complement(27305..29734)
                     /locus_tag="TU746_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL0891516.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
     gene            complement(29737..>29896)
                     /locus_tag="TU746_001167"
     CDS             complement(29737..>29896)
                     /locus_tag="TU746_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0891517.1"
                     /translation="INPMGGFSIHLIINDDPDTYLRVRLSRYDLERNLEIASNYRSEK
                     LEKLLKGE"
BASE COUNT         9189 a         6531 c         5479 g         8697 t
ORIGIN      
        1 tgagagatat gttggcttct gatttcatat aagacctgcc atcgcccttc ctgccaaatc
       61 aaaggtaagc aaaccgcata acatcgctcc tcacccaagg gcctagcctg ataatgttca
      121 ataatgctct tcatctgtcc ttctccttat catatccatc actaagctac tttcatagta
      181 taaaatagta atcctttggt caagaaatgg ctccgattac tctctatgat atataaaatt
      241 tttatatata aaatattgac atattaaaac agaaactcta tacttaatat ataaaataat
      301 tatatataaa tacgaggcag gaagggagta accagatgta ttttccagta tctgctacct
      361 tgattgaatt tttgatttta tctattgtcg acaagcatga ttcctatggt tatgatatca
      421 gccaaaccat taagcttgtc gctaatatca gggaatcaac cctataccct attttaaaaa
      481 agctagagaa atcagactat ttaactacct atagtcagga acatcaaggt cgcaagcgta
      541 actattacac cattacagcc aaaggcgaaa agcagctgat tttcttaaag gaagaatggc
      601 aaagctacaa ggccacccta gatggcatta ttgaagggag attaaggcat gacaagagat
      661 gaatacctag cagagctaga caaataccta cgaaaattac ctaaagcaga ttattatgaa
      721 gctgctgaga actcaagtca gctagaactt aacgacggca gtatcaaaga ctcttctatc
      781 actgtagctg atacaaaaga agaaaacgac tatgactata cagacccctc cgagcttgct
      841 ataaatcatg tcacaatcaa ggagaaaaac acaattaatg gcggcgatat taatatcaat
      901 accacattag caaatccaag agatattgct tatcatgtca caacaagagg caacatcaag
      961 ctcagctctc gtttttcaaa cgccaagctt aacacagacg cagcaacagg agctacttca
     1021 tttcactctg acatagccaa tactgtcaat caaagcgacc tatcaattca ttaatcaagg
     1081 gaggatatca taatgactaa acaagatttt ctagacaagc taaagcagca gatcaaccat
     1141 ttacctcaaa aggattacca agaaatcatt gaccatttta cagagtattt tgacgaggct
     1201 ggtcctgacc atgaacaagc tattcttaaa gaactgggaa atccagagga cattgccaag
     1261 gagctattaa aagccttaga tctccccgaa aaaacagacg aagatgactg gacgaattgg
     1321 gaagttgaca acaaaacaaa gtcagaagca agctcacaaa agcttgagcc aatagttgac
     1381 attcgctata gtctgcttaa ccatgattta accattgaaa ctgctgacat tccttaccct
     1441 actatttcat acgatgataa tcgcatcaca ataagccaag atagtgacgg catgctcaat
     1501 atcattgaag actcagcagt acaaacaata cagtatggct ttcatttcct agaccgctgg
     1561 cttgcaaaat atcaacccat taccttgaca ctacctgtca accaccacct gaaaaaaatc
     1621 tctggagaaa gtgacaacaa cgatgtcacc ataaggcata tacattgtga tagcattgtc
     1681 tctaacactt acaatggaac gatttctatc agtcatttat cagatagcac tgtcaaccta
     1741 agcagcaaaa atgggaacat tattttagag cattgcaata tccagtctag taaatgtcaa
     1801 gccaaaaatg ctaacctcag ctgtgacaat agcaccctaa taaattgcca gctgaacaat
     1861 aacaatggaa acatcagatt agaagcaagt cagctaacag aaaccttcat tgaaaacaaa
     1921 aacggtaata tcatagggca gcagctgtcc ttttccaatg acatcactat catcaataag
     1981 aatggaatca ttgacatcaa ttgtcctaga gaaaacctca tctactatga cgtaaaggct
     2041 tcaaataata atggatttgt aacgattagt caagaagcag gtcgtcaaac accctttaaa
     2101 gcacagctta ccatttccaa taataatggt cttatctccg taagctaaac caaccataaa
     2161 aaaagcttct agaaagagct taaaccacaa tttctagaag cttttttatt atatctactg
     2221 tttaacgata acctgttatc tcagctatta tctaggacga ttgcttgtcc tttggacgat
     2281 aaatcagcac tcctatagcc ataaagctta acaaaaagcc aactaataca ctcgtctcta
     2341 aacctatctg ggcagttaat gatattgtct gacgaaggcc agagacaata taagacattg
     2401 gaagataagg atggagaatc tggaagatct gaccactcaa ctcaatagga taagaaccac
     2461 ccgcagcacc aacctgtagc aacagcataa ttaacgaagc aaaggcacca tatcgagcat
     2521 cccagctgac caatgcagtc actaaagcca tcaaggccca tccactcagc ataataaagc
     2581 ctaaggtctt gataccgtca ttagcttcaa agcccagcag ttgaagtgca gcgtaaagaa
     2641 taacagagcc aacggtcgaa atcatgccat tgatcagtaa tttttgcttt gcccaatccc
     2701 atctatcttt aatcggctta ccagataagg cctctgcaaa aataatattt gtagacaagg
     2761 caactaccat tagagacaca gcaatcatat aaggagccat gccaatacca ttggtcctaa
     2821 ccttatcctt gtccttctct gataacgcta ctggatcaga taccatatca gcattctggt
     2881 cctctaccca agccattgaa agctggtcag aagcttttga tagtgaggtc gttaagcttg
     2941 acagacctgt tgacagagtt gtcaagccat ctgtcaactg agagctgcca gaggagagct
     3001 gattggctcc aaaagctagc tgattagcgc ctactgtaag ctgctgtcca cctgctaata
     3061 attgactgga ttgatggtta agagctgttg cccctgtagc aagagtagac aggcctgctg
     3121 taagagcttc attcttagct gtcaattgat taaagccgcc agcaagagct tgactacctg
     3181 ataagagctg ggctgttgtc gctgagtgaa cagcccttaa accagttgaa agctctgaca
     3241 atgccttgcc tgtgctaggt aggatttgat cagcttgata agccagctga ttaacaagtg
     3301 ctttaaagtc cctcagttga tcagctacac cagcacttgt tgacatagcc tctagctcct
     3361 cagacatggc ttgcagtgat gtcaacatag cctttgctga tattgttact ttagttgaag
     3421 tattggaaat agctgagctc agctcctcct gctgctcaga gttgagacct tgataggtag
     3481 ctgtagcttg tagagcggct agctgattgt tcttgtcagc agtatcatct accacaagct
     3541 cctgcactaa acgcgtcata tcggctaaat gcttagcaat ggctcctgag tccacatttg
     3601 gtgccaaaga caaggaaaga ttggtcttta gctgctggat agcctgatta agctttggta
     3661 ggctagccat taaagcttga atattagctt gtttgtcttg agacagatca cttcctagag
     3721 ccaattgggt caagccagca tttaactgat tagcaccctt ggataaccga gaaacaccat
     3781 ctagatacgc tggcatatca gctgctagct gtcctaagcc cgcggtatca agctgaccaa
     3841 caccggctgt ataggcagct ataccactag atagattacc cgctccttga gacaagcgag
     3901 cacttgattc agacaaggtg ttcaaatgcc ttgacattag ctgactgctt gccctagcaa
     3961 ttactaagcc agcggctaat tgctgaccgc catttgaagc ttcctttaga ccagattgga
     4021 gctgatgcat gctcttaaaa acggaggtga tataggtctt ccttatattt ttagaaacag
     4081 cctctctcaa gtgattcata gcagattcac ccattttaga agcgataaag ctatggccct
     4141 tactagtttg atagctaaca atcagcttct ctggctgctg atctaatagc gtagtggcct
     4201 tttgtgacaa atcctttggc aacgtaatcg tcatataata acgacccttt tccaagccct
     4261 tttgtgcggt atctgcagcc acaaaatgat aatccaattc cttattttta gacatattgt
     4321 ctaccatatc gttaccaata gtcagtctct tgttattcaa gtaagcaggc ttatcctgat
     4381 tcacaactgc tacaggcaac tgatcaaccc gaccataagg atcccacatg gaccctaaaa
     4441 aggacaaatt atagagagct ggtactagag caaccccaat cattgtcact actagcttac
     4501 gatttttgat tattgctttt aatccttcta gcattatttt ttctccaaat agacatactg
     4561 ttcaaaaatt atgataaaat atattataca aataaagtga cattttacaa ggaaaaaata
     4621 aattttttag acataatgtc tacaagtgtt caaaaggaga taatgatgga tagccgcaag
     4681 cagcaaacca agaaggccat tcttaatgca atggtgagct tactaaaaac cgaaagcttc
     4741 gatgatgtaa caaccgttca gcttgctaaa atggcaggca ttagtcgttc tagcttttat
     4801 actcactata aagacaaata tgagatgatt gattactatc aacaaacctt ttttcacaaa
     4861 ttagaataca tttttgaaaa agaataccaa aacaaggagc atgctttttt agaagtattt
     4921 gaatttctca agcgagagca actactatct gctctgctat cctccaatgg tacccgagaa
     4981 atccaaagct ttatcattaa caaggttcgt ctgttgatca ctaccgatct tcaggacaag
     5041 ttcagtaagg acatcttgtc cccaaccgaa aaggaatatc gaagcatcta cctagcacat
     5101 gcctttttcg gtgtctgcca aagctggatt gctaaaggaa aaaaagaatc ccctcaggaa
     5161 atgactcgtt tcgtcttaaa aatgctatct aaaacatagt cctgcactaa tgatgtcaaa
     5221 tccagtacca aaaaacaact ttgtaaacta tttcttactg agtttataat gatctttatg
     5281 cctaacaata ccgacctcca atcgttagac ttttggtcta acctttgggg tcggtacata
     5341 aatcagctaa ccgctcaacc aaaaaagccc actgttgtgg gcttcttata atataaagtc
     5401 ttatcttaaa gcattttgtt gtagaattca acgacaagtg cttcattgat ttctgggtta
     5461 atttcgtcgc gctctgggag gcgagttaat gatccttcaa gcttttcagc gtcaaatgaa
     5521 acaaaagctg gacgtccaag agttgcttca actgcctcaa ggattgcagg aaccttcatt
     5581 gatttttcac gaacagagat gacttggcca atctcaacgc ggaatgatgg gatatcaaca
     5641 cgcttaccat caacaagaat atgaccatgg ttaacaaact gacgtgcttg acgacgagta
     5701 gttgcaagac ctaagcggta aaccacattg tcaagacgac gctctaaaag aagcatgaag
     5761 ttgaaaccaa gagttccttc tttgattttt gtagcttgta cgaataggtt acggaattgt
     5821 ttttccccca taccatatga aaagcgaagc ttttgcttct cagcaagttg caagccatat
     5881 tctgaaagct tgctacggtt gttagggcca tgctgaccag gtacgtagtt acgacgtgcc
     5941 aattccttac ctgtgcctgt caatgacaag ccaagacgac gtgattgttt ccatgatgga
     6001 ccagtataac gtgacatgta tcatgtcctc ctctaaaaaa tataacgagg aaataactgt
     6061 ttgaaaaatc ctgattcgtg caggaggttt tcgcctaaac agcaaaggtt actcaattta
     6121 gttaaccgcc tgttgacgag cttcatattt ttctgctgtt atttcacaca aaactaattg
     6181 taacatgaaa aaggtattga ttcaagtttt ttttacattt ttaatatcat atcatcaaaa
     6241 atggttagct gtaagctcaa agatgatgtt aatcatatgg caaacaagct tttacacaac
     6301 acttcccgag taaacaaggc tttttaatac cgataggaaa ttctttgaaa atagcatatt
     6361 atgttttgat atctaatacc gagagtctca gagtaactgc ttttcaagaa agctagtccc
     6421 tattattagt ccgggcttca ttcatttgct aataagttct tcaaggcttc aaattgattc
     6481 atatctttac acagctgtca acaaagtgta aagaaaaagc cctaaatggg cattgatttt
     6541 tcaatcaaaa taacgaatca gtgttttttc cgtcaaaata tctgaatagg tataagactc
     6601 aacataagaa ttattcgctt cccctgaagc atctgggttc ccctgatact caatgataaa
     6661 taaagaaggg taaacctcta tcaatctgcc aaccttattt ttttcacgct tacgaccatt
     6721 ttcaagtgtt aactcaacca actgaccttc atgagcctta atgtcttcct ttattttttt
     6781 cattttggca acatctgtaa atgcatcact cattctcttt ccctctttct tatctttcct
     6841 caaattgagc tattgtcgaa aatttattgt attccttttg aaacatcagc ttaactgtcc
     6901 cacgcgcacc tgccctattt ttctcaagaa tcacctcaat tgtattatcc tcaagagcct
     6961 cttctgtgct gtcgctttct ttacgataat aatcatctcg gtacaaaaat gcaacaatat
     7021 ccgcatcctg ctcgatagag ccagactcac gaatatcaga caaaactgga cgcttgtcct
     7081 gcctctgctc aacaccacga gaaagctgac tcaaagcaat aacaggcact tttaattcct
     7141 tagctaaaat ctttagctgc cttgaaatat cagaaacctc ttgctgacga ttttcaggtc
     7201 ttgtaccagt gatcagttgg aggtaatcaa tgacaattag ccctaagcct ccctcaacct
     7261 cctgagacaa tttacgtgcc cttgctctga tctcagtaat cttaatgcca ggtgtatcat
     7321 caatatagat aggtgcttct gccaaggctc cttgggcaat ggtcacatta ttccagtcct
     7381 gatcagtcaa ctgaccagtc ctcaagctat gtgaattgac cattccctca gcggccagca
     7441 tacgatcaac aaggctttca gctcccattt ctaaggagaa aatggcaact gctctctttt
     7501 gctttgtacc aacattttga gcaatgttta agacaaaggc tgtcttaccg actgcaggac
     7561 gagctgctaa aataatcagt tgatctgggt gtaaacctgt tgtaatcttg tcaagatccc
     7621 taaagcccgt tggtaaacct gtaacgtctg atgtctgctt agaacgaacc tcaagatttt
     7681 cataattaat ctttaaaacg tctgagatct tacgaaagcc actgcgattg ctatgctcac
     7741 tgatatcaac caaggccttc tcagcacttg caataatatc ctccgagtca gatgctcctt
     7801 cataggctaa gtttacagtc tctgtcaacc tattgatgat atcgcgtagc atagcctttt
     7861 cagctactat tttagcatag tattctgcat tggcactggt aggtacacta ttaaccagct
     7921 caacaatata agacaagcca ccaatatgtt gaaggtcccc ttgatcatca agaatcgtcc
     7981 ttaccgttgt tgcatcaata gcatcatttc gatcactaag ccttatcatt gccctgaaaa
     8041 tgaccttatg agaatactta taaaaatcct ctggaccgat aaattctcta acggtaatca
     8101 acttgtctgg ggaaataaag atagagccta gtacagactg ctctgccaat aaatcttggg
     8161 gttgaactcg taactcagca acttcaggca aactcagcac ctccaaatct tttttaggct
     8221 gatgtgctat gcctcagcaa tgtttagttt tatttcagct gtcacttctt tatgcagctt
     8281 aactggcact tcgataagac caatagcacg aatagggtga tctaaaacaa tatgacgctt
     8341 gtcaaccttg accttaaatt gcttttgcaa ttcctcggaa attttcttag ctgtaattga
     8401 gccaaaggta cgcccatctg gtccaacctt ttccttaaac tggacacgag ttttttcgtc
     8461 atctaagatt ttcttaacag ccttagcctc tgctaggatt tcagcctggg ctttttcctc
     8521 agctttttgc tgccctctta gctggccaat tgcttgactg ctagcttcct ttgctaaatt
     8581 tttcttaatc agaaaattct gagcataacc agtgggaacc tccttgattt ctcctttttt
     8641 tccttttcct ttaacgtcaa ctaaaaaaat gactttcatg actctacctc tcttgtttct
     8701 ttcattgtgt tatcaattgt ttctagtaac agctgcttag cctcgctaag actgatatgc
     8761 ttcatctgac acgctgctaa gttgaaatgt cctccgccgc caagcttttc catcattctt
     8821 tggacattga tcttactacg acttcttgct gatatagcaa tcttatcagc tcctgtctct
     8881 acaataacaa agctagcctc aatatgggcc attgatagta tggtatctgc tgccttacta
     8941 gcaatgacat tactataata ttgcccagca agcccagttg caacgataat ggagtcgcta
     9001 aggcgctcac ctctgagaat gatctcatta acctgcttat agtcatcaaa atcagttgct
     9061 gaaatatttt gaatttcgac gctatcacta cctctgcttc gtaaataact ggcaacatca
     9121 aaggttctac tggtgacacg tgttgaaaaa ttcttagtat ccagcataat accagccatc
     9181 aaaacacttg cttgaatctt gtttaagcgc ttcttcgcat tttgaaactg gattaattct
     9241 gtcactagct ctgcggcact gcttgcacca ctttcaataa aggtcaagat agcattatct
     9301 ggaaaatcat catctcttcg gtgatgatca acgacaataa catcttgaaa ttgctcgtaa
     9361 aattccttag acaaggttaa ggaaatctta gagtggtcca ccattactaa cagtgatcta
     9421 ggggtcgtaa gccccattgc ttgagaaata ctgataagac gtgtcttacc atcagcctgt
     9481 aagcgctcaa tagctctttc aatgtctgga ctcatctcat ccggattata gacagcaaag
     9541 ctgttttcaa taatgttact agcaaaaaat tgcatgccaa cagccgagcc taaggcgtcc
     9601 atgtccagtt tacggtgacc tacgataaac acattatcaa ccattttgat acggtctgaa
     9661 atagctgtca tcatggcacg cgtcctagtt ctagagcgtt taaccgtaga aacagagccg
     9721 ccaccaaaat agaccggatt tgtatggtct gcattttcac gaataacaat ctgatctccg
     9781 cctcggacaa gagcaatatt cagattctca agagcaacct gaccaatttg acaatgattt
     9841 tcctctccaa aggaaatgcc catacttagg gtcaatggta gctgcgcttc ttgggcttcc
     9901 tttcggaact gctctaaaat agaaaactta tcgtccatca gcccttttaa gatcttatag
     9961 tctgtaaaaa agtaaaaacg atccatatta acacgtcgat aaaatacctg cttagactcc
    10021 ataaactcag ctatgaaatt agccacaaat gaatttatct ttgacgtatc agcatcagat
    10081 aagtcatctg taatgtcgtc ataattatcc acagaaataa taccaataac tggctttagc
    10141 aagctagaat ctgctgattg tctactacca acagagctat caaaaaagta aaaaatacct
    10201 gatgccacat caatataaga cgtgtatcga ttgccagaaa cctcaaaggt ttgagaaata
    10261 tcacttttac gcttatcagt gagaagctgt tggatcatct gttcctgtaa aaaaccggcc
    10321 tcatcagtga aaatcagctc tgcgtaagga ttgtaccatt caatagcatt ggtttcttga
    10381 tcaaactgaa taacaccaac tggcatgtta tccagtaatg tttttaaatt attttctgtt
    10441 tgttcgttca atagctcaat gtggtctaaa tcagacaatt cgtaaacctt tttttgatac
    10501 caaagcaagg ccgcaacaaa caacaacact aaaaaaatag ctagtgtaat cagcattttt
    10561 gattgcatga ttctaacaca taaggctagt aagccgaata aaatcaactc catcataatt
    10621 aaatgaatgg tttcaaaacg aaatcttttc atctttaacc tcttaatccc gtattatacc
    10681 ataaaacagc cctgaaatac agagctgtca gtggttttga gattacaatt tgatgactat
    10741 tatgttttac ggcgagcctt tccattacct tcaaggtaaa ccattaaaat gctaatatct
    10801 gccggattta cacctgaaat gcgactagcc tgaccaatgg tttctggatt gattttctta
    10861 aatttttgcc ttgcctcagt agcaattgag tcaatagcgt cccaatcaat ggtcttagga
    10921 atccgctttt cctccatacg cttcatttta gcaacctgat caagggcctt tttgatatag
    10981 ccttcgtatt tgatctcagt ttctagtagc tcaatcagct tagcatctaa tccctcagca
    11041 gcaggaccta taaatgacac tacagtggca tagtcaacct ctggtcgacg cataaattcc
    11101 ttagctgtca ttgcgtccgt caaggactta aagccaagct tttgaacacg agcattggtt
    11161 tctttgattg gctttaattt gatactatct agcctcttta attcattgtc aaattgattt
    11221 ttcttgattt caaaggcaga ccaacgctca tcgtcaacca agccaatctg acgaccaatt
    11281 tcagtcaatc gcatgtccgc attatcatga cgaaggataa gacgatattc tgcgcgtgat
    11341 gtcagcaaac ggtaaggctc caaggttcct ttggttacca aatcatcaat cattacacca
    11401 atataagcgt cgctgcgctt taaaatgagc tcaggcttac cctgaacctt caaagcagca
    11461 ttgataccag cgacaaggcc ttgaccagca gcttcctcat agcctgaggt tccattggtt
    11521 tgcccagctg taaaaagccc tgaaatcatc tttgtttcaa gggtagcacg aagctgatga
    11581 ggtaatacaa tgtcatactc aatagcatag cctgttctca tcatctcagc attttcaagc
    11641 cccttaatag agtgaaccaa ttccttttgg acgtcctcag gaagacttgt ggatagacct
    11701 tgaacataga cctcctcagt gtcaaagcct tctggttcta aaaagagctg atgacgctct
    11761 ttatcagcaa atcgtacaat cttatcctca attgatggac aatagcgtgg gcccactccc
    11821 ttgacgactc ctgaaaacat aggtgctcga tataggtttt tagtgatgat atcatgacta
    11881 atctgattag tgtaggtcag ccagcaagga atctgattag ccaaataatc tttgtcctta
    11941 gacataaagg aaaaatgatt tggagtcaca tcaccaggct gaatctctgt cacctcataa
    12001 tcaatagaag aagccttgac acgtggtggg gttcctgtct taaagcggcc aatttcaaga
    12061 ccaagctttt tcaaattatc agctagtgtc actgaggcca agctgttatt cgggccagac
    12121 gaatatttca attctccaag gataatctca ccacgaagag ctgtacctgt tgttatgatc
    12181 actgcctgag ctgcatattt ttgccctgtt gctgtcagca ctccaacaac cctaccattt
    12241 tctactaaaa tatcatcaat catagactgg cgaagagtga ggttttcttg cttttcaaca
    12301 gtatgcttca tctcacgtgc atacaagctt ttatctgctt gagctcgtaa tgctcgaact
    12361 gccggtccct tacctgtatt gagcattttc atttggatat aggttttgtc aatgtttttc
    12421 cccatctctc caccaagagc atcaatttcg cgaacaacaa tacccttagc tgaccctcca
    12481 atagagggat tgcatggcat aaaagccagc atatcaagat ttatcgttgc taataaggtt
    12541 ttacacccca tacggctagc cgctaagctg gcttcaacac ctgcatgtcc tgctcctaca
    12601 acgatgacat cgtaggattc tgtaaattca tgtaccatat ctactccttt atctcaatat
    12661 gttttatatg ctgaggctgc ctgtcccaat gctttatagc cctttttaaa caactaggat
    12721 tgagccttat cttatctaga tcatcaagag caacccactc acaaacccta gtacaatcac
    12781 cctcaactac agaagggcta gaatcagata atagactcac aatataatga aactcaatct
    12841 gatgaaagtt cactccttct agacaaaatt gattttcaac cacaaaggct aactgagcaa
    12901 ctgaaacctc agctcctacc tcctctagaa cctcacgctt gacagcttct tctgtgcttt
    12961 ctccaacatg aatagcacca cctaaaagat aatagtcctc tttgggtgat ttggcaagat
    13021 aaatatagcc atccttaatt attaacgctg aagccctaac accaaagcta tggtctgcta
    13081 tccttgttct aaaatcctga accatctttt ctccttgaca ctgtttttaa gctataaaaa
    13141 tagtcaaaac ctgagaaagc tgtaagccaa aaagacttac aattcccatg agctttgacc
    13201 atcatcgtta ttgttaacct tattctatca aaatctgcca gcttgtcaag acttatcaga
    13261 tgacaaaacc gtcaacttta ttgacacatc tgtcaattaa catgtcaagc taaatatatt
    13321 gacaaggctc gccatcttta tacgccatat caataatacc accaccaaga cactcatgac
    13381 catcataaaa aacgactgct tgaccaggtg taatcgcacg ctgaggctca gcaaaaacaa
    13441 ccttagcttt gtctttcttg acatgaaccg tcaccttaga atctggctga cgatagcgga
    13501 actttgctgt gcattctaag gtgaattctt caggaacttc tcttgtaaac tgaatgacag
    13561 aagcgtcaag actagttgac attaaggact cgtggtaaaa gccttgacca acataaagga
    13621 tattttgtga aaggtctttt ccaacaacaa accaaggctt gttatctcca ccctgctgac
    13681 caccaatgcc aagtccccca cgttggccaa tagtataata catcaagcct gcatgctctc
    13741 ccatatcacg accatcaaca gtcatcatac gccccttttg agctggtaaa taatggctaa
    13801 gaaaggtctt aaaattcttc tcactaataa aacaaatccc tgttgagtct tttttctttg
    13861 ctgttgcaag gcctgcttgt tcagcaatag cacgtacctc tgatttttgc aggtgcccca
    13921 agggaaacat ggttttttgg agttgctctt gtgatagttg gcttaaaaaa taggtttgat
    13981 ccttaccctt atcaagacca cgcagcatat ggactacacc attctcatca cgtttgattt
    14041 gggcatagtg acctgttgcc acataatcag cacccaatgt catcgcataa tcaagaaagg
    14101 ctttaaactt tatctcctta ttgcacatga catcaggatt tggggtgcgt cctgaacggt
    14161 attctgctag gaaatactca aacactctat cccaatactc tttttcaaaa ttaacagaat
    14221 agtaaggaat accaatctga tcggctacgg ctgccacatc tttataatcc tcagtcgccg
    14281 tacaaacacc aaattcatct gtatcgtccc aattcttcat aaagacgcca atcacatcat
    14341 atccctgctc ctttaacagc aaggcagtta cagatgaatc aacaccgcca ctcatgccaa
    14401 caacaacacg tgttttcgag ttatctgtca tcatttattc tcccatcaat ataagataca
    14461 aggacatgag aaaaagaata gaacgaatca acttgcctaa acaagactct agcaaatggt
    14521 tcatttctat attttttgtc tttgtccaag tgttttctca aagctcgatt tgaaggtcga
    14581 tttgaagcgc cgctagacgc atgactatta taacagtatt gtctcttatt tccaacaata
    14641 tcttttttca taacaaacga catttgatta gcgatttgtt ataataaaaa ggataaaaag
    14701 agcatggagc atatatgaac acacaaaaat ttcaatcagt ttttgacatc attggaccag
    14761 tgatgattgg accatcgagc agtcataccg ctggtgctgt tagaatcgga aaggttgtcc
    14821 actccatttt tggagaaatt cctgatgagg tgacctttca tctatacaat tcatttgcta
    14881 agacctatca aggccatggt accgacaagg cactagtagc tggtattatg ggcatggata
    14941 cggataatcc aaacatcaag aattctcttg aaattgctca tcaaaagggc attaaaattt
    15001 attgggatat tttaaaggat agcaatgctc cccaccccaa tactgtaaag attagtgtca
    15061 aaaaggctga taaagcaatg agcattacag gtgtgtcaat tggaggagga aacattcagg
    15121 tcacagagct aaatggtttt tctgtttcct tgtctatgaa tactccaacc ttgattattg
    15181 tccatcaaga tatccccgga atgattgcta aggttacaga tatattgtca gctagtgata
    15241 ttaatatcgc tcaaatgact gtgactcgtg aaagtgcagg tgagaaagcc attatgatta
    15301 ttgaggttga ttctcgtgat tgtcaagttg ctgtcaagca gattgcaact attcctaatc
    15361 tgcataatgt caatttcttt gactagaaag gtatattatg ttttacacaa ttgaagagct
    15421 tgtcaagcag gctgatgata ggtttgatgg taatgtagca gagctgatga ttgctacaga
    15481 ggttgaaatg actggtcgaa gcagggcaga aatcctatcc atcatgtcac agcatttaca
    15541 ggtaatgaag gattctgttg tcagcggatt gacagcaacc aaatctatta gcggattgac
    15601 tggcggtgat gctcttaaga tggatcatta catcaaaaaa ggaaaggggc tttcagatca
    15661 aaccatttta acagctgtga gaaatgctat ggctgtcaat gagctaaatg caaaaatggg
    15721 acttgtttgt gcaaccccga ctgctggaag tgcaggctgt ctacctgctg tccttgctgt
    15781 tgctattgat aagctcaagc tatcagaaaa ggaacagctg gactttctct ttacagcagg
    15841 tgcctttggc ttagtcattg gaaataatgc ctctatctcc ggagcagaag gaggctgtca
    15901 agccgaggtg ggctctgcct ctgcaatgag tgctgcagcc cttgttaagg cagcaggtgg
    15961 taccgcttat caggctagcc aagcggtagc ctttgtgatc aaaaatctat tgggattggt
    16021 ttgtgatcct gttgctggct tagtcgaagt tccctgtgtt aagcgtaatg cattaggatc
    16081 aagctttgct cttgttgctg ctgatatggc attagcgaat attcagtcac aaattcctgt
    16141 agatgaggtt gttgatgcta tgtatcaggt tggtgccgca atgccaacag cctttaagga
    16201 gacagctgag ggaggattag cagcaacccc aacaggtaga cggtatagta aagaaatttt
    16261 cggagactaa tataatcaag taacgataga ctgaggagac gtcatgaaag caatcctatt
    16321 tgacttagat ggtactttgg tggattctag tataggaata ctaaatgcct ttgaatacac
    16381 ctttcaaaaa atgaaaatcc cttgtcctga tcatagcata ttatcgtctt acatcggacc
    16441 acccttagaa gcgacctttt cagcattttt taggaatcag catgatgtcg aggttgctat
    16501 aacacacttt agagattttt acagggaatt aggcatttac caagcaaggc tttattctgg
    16561 aatcacagag ctattagata atctctcgca agaaggtctt gacctctatg tgacaactag
    16621 taaatatgaa cctatggcaa ggcaaatgct tcaggattta acgattagcc attatttcaa
    16681 agctatccta ggctctattt ctaatcggtg tcacaagttg gatatcgtca aggcatgctt
    16741 acaagatttt gctattaata aaaaagaagc tataattgtt ggagatacca aatttgacat
    16801 gattggtggt aaacaagcag gcattacaag acttggagtt acttggggat ttggttgtca
    16861 agaggattta caagcacatg gcgcacaata cattggacac acaccccaag aggtgattga
    16921 gattatccag tcattgtaaa acgatactaa aaacctatca tcacacaaga tgataggttt
    16981 ttaacgctgt tatctgttct tagtagcccc aagctgataa gccctgtgca cgataggcat
    17041 ttaaggctga atttacctga tcctgaacgg ttgcagttga tccccagcct ggcatggttt
    17101 ggaataatcc tgaagcacct gaaggattag ctgcgttagg gtttccattt gactcacgag
    17161 cgataatggc ttcccaagta gcttgtggaa caccagtagc tgccgccatt tgagctgctg
    17221 cttcactacc gatagcccct gcggtattgc cgttagaaag gattactcca ttgctataag
    17281 ccactggtgt agctgcatac tgagcttgag gagcagcctc ttgcacagca ggactagcta
    17341 cctcagaagc tactgattcc tgagctggtg ctgcatcagc agaggaaggc tctgcctgct
    17401 cagctggctg ctccttggtt gcagcctttg ctactgttga tttttttgtt ttatgatgtt
    17461 tcttcacaac cttagtatca gaagctttag cataggaatc agtgtttaca ttttcacttg
    17521 aaaaagcaaa aactactgcg agcaaagcaa tagcagctgc tacaatgcca aaactaaaat
    17581 aacgttgttt caaaatgtct tgtttaaaca ttaaataaat acctcacttt tctctgttat
    17641 ccatattaac tgttaattat tacttgtcta tttaagatat attaaaaata ttacagcaat
    17701 attgatattc caagttttct agcctgatat cagtgttttt tgagcttaag aagctcaaaa
    17761 taaaaacaat gcctaagttc agacctgtgt aacagatgat ttaagcattg ttattattaa
    17821 taaattctag ttgctacagc ctaacaaagg ggctgctgta atatagctag gtgagccttg
    17881 agggactttt tagacagaaa aggaaaatcc ccaaaatgac taccaaaata atggctagag
    17941 tgtcttttaa ttgccagctt agcaggcggt attttgttcg actgtcaccg ccttgatagc
    18001 ctctagcctc catagcgatc gctaaagcgt cagctctttt aaagcttgaa gcaaaaagag
    18061 gaatcaaaat agggataatc gactttacct tttgaataag attgccttct ccaaaatcaa
    18121 cacctcgcgc tttttgcgca ttcataatac gagttgtatc gtccatcaag gttggaacaa
    18181 accgtaagct caaagataac atcaaaccga tctcatgggc aggtacctta aacctaacta
    18241 aaggcttcaa cagcgcttca acagcatcag ataagcttag tggggtggtg gttagggtta
    18301 acagcgtgga aaagaaaata atcaaaacaa atcgcatgaa aatcaaaatg gcttgactta
    18361 atcccaagct tgttatctta attattccaa gctgaaaaag aactgatcct ccctgtgtaa
    18421 aaaaaacttg aaaaagcgtt gtaaatagga taataccaat cataggctta acaccattga
    18481 aaaagaaaga ccattttatc tgtgacaaga aaatcagcag caaggtaaat gctaacagca
    18541 aaagattagt taccacatta ttggcccaaa aaataatgat aatatagata atcatagcaa
    18601 gcagcttgct tcttggatca agccgatgaa taattgaatt cccaggaata tagcgaccaa
    18661 gaatgagttt atccatgctt taatacctct cttaattcct ccaaagtaat gggtaaatag
    18721 ggtaaatcaa agccttgctt agccaggcgt tgggcaaagg ctgtcacctt agggacacct
    18781 aattgttttt cttttagcaa atcaatgtgt tgaaaaatag cctttggctg acctgataag
    18841 atgattttac cagcttcaag gacataaaca aaatcagcat aattagcaac atcgtccatc
    18901 agatgtgtca ccagtacaat ggtcatgcct gattgatgga gcgatttaaa aagactcatt
    18961 aattcctttc gccctttggg atcaagccca gcagtaggct catctaacac caaaatatcc
    19021 ggctgcatcg caagaatacc cgcaatagca accctgcgca tctgcccacc agaaagctca
    19081 aatggatttt taccaaatag ttcctctgaa atccctacta gggttaattt ttcacgcgct
    19141 aaagcttccg cctctttctg agaaacacca aaattttgtg gtccaaaggc aacatccttc
    19201 aaaaccgttt cctcaaaaag ctggctctca ggaaattgaa agactagacc aacctgctta
    19261 cgaataggct taatatcttt attttttgac tgactagtta tctccttgcc tgctaccgta
    19321 accttgccgg tggtcggcag atgcaagcca tttaagagct gcataatcgt tgacttgcct
    19381 gagccagtat gaccaataaa agccgtataa gagccgtcta caatatcaag attaacgtca
    19441 aaaagggcac gcccctcaaa gggtgtccct gcttgatacg tgtagcttac attttggaaa
    19501 tgaattgaca tagctgttcc tctaattcct tttctgtgag atagattccc tgtatagggt
    19561 agccgtcttt ttttagcata ttaacaacag aggttgtaaa aggaatatct aaacctagat
    19621 tgatcaattg attgccccta gcaaatagct cctgtggagt cgagacagac tcaacacgcc
    19681 cattgttcat caccaaagct cgatcactaa gagccacctc atcaagatca tgtgtaatag
    19741 atataacagt tagttggtat tcttgtctaa tagattgaat tgtccgaatc aactccagac
    19801 gcccctttgg atccagcata ctggttgctt catctaaaat gatgatcatt ggccgcatgg
    19861 caacagcacc tgcaatagca acccgctgct tttgaccacc tgataatctg gaaggctcct
    19921 tatccttaaa agcctccata ccgaccagct gcaacgcctg atgaacacgc tctatcatct
    19981 cctgatggga aacacctttg ttttcaagac caaaagcaac gtcatcttcg acagttgcac
    20041 caacaaattg gttatcagga ttttgaaata ccatgccaat tttatgacga atgtcccaga
    20101 cattgtcctc tgtaagaaga tcaccatcaa caaaaatctg gccggcttct gctttcaata
    20161 gcccatcaat taacctaaca acggttgact tgcctgagcc attatgccca atgatagaca
    20221 accactcgcc ttgtttcaca tgaaacgtca catcatctag ggtatatcgc tcctggtcct
    20281 gcttatactt aaatgtaaga ttcttaactt caataatatt tgacattgtt atttaaaggt
    20341 atccttaaaa agaaagcttg ctcctttgaa ataatcgtaa cctgaataaa tcgtaaacaa
    20401 tagagcaata tacagcaaaa cagtgcctaa aacagtccaa tgacacagta aaaagatgat
    20461 ggaaagcatc tgtgctactg ttttgatctt accaggcata gcagctgcta ggaccttatc
    20521 tccagtctca accaatagca aacgaagtcc tgtaacagct agctcacgac agataataac
    20581 cgctgacacc caagccggta ccagctctaa gcccactaac ataataaaag cactcatgac
    20641 aagcatcttg tctgccaatg gatcagcaaa tttaccaaaa ttagtaacaa cctgccactt
    20701 acgtgcaagg taaccatcta aataatcggt caggcttgcc actgcaaaaa taatcgctgc
    20761 aaaggtatgc caaccgactg tctttgaaaa agaggtgatc aacaaaaaca atggaatcat
    20821 gacgatacgg gcgagagtta acaaattggg aatattttct tttttgatca tgcttatacc
    20881 ttattattgt atcttcagtg tgatatagct gatatcagta cttgtcattg ctgataaatc
    20941 taggggctga ccatcaattg ctactgaaac accctttgtt acgcctagtg tcaacaagga
    21001 ttctgttgtc tcagcaggca aggtagtaga ataagtcgga ttgtcctttg ttagggtcat
    21061 accagcctca ccaatttccg aattagtgag ggaaatccaa ctgctctcag catcagtcag
    21121 tgacactgta acatcaacag cttcttttga tttagtaata ttagcaatca agtaattctc
    21181 tgcgccctct gttgtgatca ccgtcttagg ctcagatgag ctggacgctg ttgagtgact
    21241 gctttgtgat gacttaagaa aagacatctc agcctctttt gctttttgac ctttatcaaa
    21301 ttgcttccaa acagcaaaac caataacacc aacaatagcc acagcaataa gacctagtaa
    21361 ggctgatgga aaggctgatt ttttcgtttt agcactattt ccataacgac ttagccttga
    21421 agcactggtc tctctagtcc gtctatggtc agtagcctta aagtgactag ctgtaggagc
    21481 tgatttgctt gaggatagtg acgtcttgac aggaatcact agggtttctg gttgagtcct
    21541 tgaaggctct ggttgagcta ttttttcaga atagctattc tcttgtagcc tttttttgct
    21601 gagcttttct tcaacgattt gtgtgactga tggtgtacct gtttcctttt taaagctcac
    21661 ctgcagctga tacaagcgtt ttaagctatc aaagtctaag ccaacaatat cagcatattg
    21721 ctttagaaaa tgaccaaact tttcttctgg aatgattttg aactggtcaa gctccattgc
    21781 caatagataa tgcgaggaaa tgccagtttt agcttcaatt tcgtctaatg ttatgttttt
    21841 tccgacacgt gtttctctta ataattcacc gagacttgtt tctctcatac gagtacctca
    21901 aaaatattgt aataagacca ttataacaga ttttaagcta tttgggaaag actgtaaaat
    21961 ctgaagtagc tgcatgctca aaaaacaagc ttcctatttc gataatatcc tttaaagcta
    22021 gggtctcaat aatcctagga atatcaaaat aggtctcttg ctctgataaa tgaaggctaa
    22081 attggcttgc cagctgatca atagcgtcta agctttgcat aaaatcccca tacatttcct
    22141 ttttcactag ctctaagtgc tcctcattaa cgtctcttga gcatctaaaa tcggaaatct
    22201 tttttctaat gctgttagac attgcaatag gctgactagt atctgaagaa atcaatacaa
    22261 attggaaatc cctttgaatg tcaacctcta tatcaaagga gtcgtctatc ttgccctttt
    22321 cataccaatc ctgataggtt tttgacgtcc agccaaggag caccgctagg agcagtctaa
    22381 gagctacctg ataggtgagt agagaatact cgcttgacat tagctgaccg cgaaagccga
    22441 ctgctaattt ggcagtcgca acgtccatat caatagatct agacttgatc acagggtagt
    22501 aggtcaatgg agctatctgt acatcatact gcgtctgact tggttgacta tcttgaaagg
    22561 cttcaatagc tgtaaaggct tcttcaatgt caatatcgcc aataatcgtt aagaccatgt
    22621 tagaagggtg ataaaaataa gcatggctgt cagccaataa agagcctgta atgtccctga
    22681 tagactcctt ggtcccagca atatcaacag ctaagctggt attgggaaag aggttctgta
    22741 agataccact gtaagcctga taatcaggat cgtcctgata catctcaatt tcttgagtga
    22801 taatatgttt ttcacgatta accgactcct ctgtaaagct aggagctgct acaaattcct
    22861 gcaaaagtct cagactttct tgccattcat tgacagttga aaagaaatag ctcgttttat
    22921 caaaggttgt aaaggcattt gtttctgatc ctaactgtgt aaatgtaaga gcaatatcat
    22981 taccatcttt atcctcaaat agcttgtgct ctaagaaatg agcaacacct gacggcaagt
    23041 caaacctttg acaattgact gtaaagcttg tgtcaagaga accaaaacga gcagtcagca
    23101 tagctgtttt ctcagaatag ccctctttct ttatcaaata aacccttaaa ccatttgcca
    23161 attgaccgta gtgtaaggtc tctttaatgc tgggatagtc ttttttcagt agtgacgtca
    23221 tcttattttc cctctaaaaa atatacagct tgcagcttga gtagattagc tgtcctgaca
    23281 atatctagct tgctaacctt gtcaatctcg tcaagccaac ttgacaaagt ataggaagga
    23341 tctatataag atctcatgta ttccagctca atcaaggctt tactattatc ctcagatagc
    23401 aaggcgttat tttttagcat tagctttgtt ttcttgacaa ggctgcttga aaagcgcccc
    23461 atcttgatgt cattgagctc tttaaccatt agctgcaggg ctcttgtccg gtgctgtcta
    23521 tctatgccag cataagcctc aaataagcct gtgtaaacat caaatcgact accaatacta
    23581 taggccagcc cctccttctc acgaatttgg gtaaagaagc gagagtgtgt aaaggctcct
    23641 aatagaccat ttaacacaac taaggcataa tactctgctt gcccataaac cagcggaaaa
    23701 tgataggcta gctctaaaac agactgatta agctgctttt gctcgaccaa ttcgttgaca
    23761 acattgacag gctgctgtaa ataaaagaaa tctagctttt tcctgcgtcc ctcaaaggga
    23821 aattggtgta acaattgtac catacgataa tcatcaaaat caccaagaat aaaaatatca
    23881 atctgatcct cattcaacat tttatgaaat tcttgatagc ttgtgtaggc tgtttcttta
    23941 gcaattaact cagtattacc atattttgac agcttcaggc tatcattagc ataaaataat
    24001 tgcttggctt ttagggcact ataataaaag gaatcctcct tatctgcctc gacataggtc
    24061 atcaaatgtc ttttttcgat gtcaaatagt ttgggctggt actgagccac tgataacaaa
    24121 ggagaaaaaa ggatatcctt tagaaattga atcatttcgt ctagaagctt ctctccataa
    24181 aaagcatact gatcctgaat aaaggtaatg tcaatatcca caatatgaac caaacccttg
    24241 gttgacacat gagttgacag gcttgctcca tacatttgtg ctaatttttc tctaaattgc
    24301 ttggcagtag gataggtatc gttagccgtt gctaacattt gagctactaa gactcgcttt
    24361 gctaccgttt tttgattcaa atcacctgaa aagcgaaacg ttatctgatt cgttttaaat
    24421 gttttgtttt ttatcagatg aagctgaact ccctgaataa gtttcataat atttccttat
    24481 taataaatgt gtgatctcta gaattatacc atttttatcg ctattcgttg agtgttaaca
    24541 tcagtctggt agcctatttt gactctttat caaaatgcta tcctgtggct atagtctaga
    24601 ctttagaagg tcagcatttc agcattatta tttagtggct ttttatgcta taatgacttg
    24661 aatgacaaat tggagatgac tatgacatac acactattta ctgactttat taccctacaa
    24721 gctttattaa aggagcaagg tattatccaa agtggtggtg ccattaaagg ttttttagct
    24781 caaacagagg tttttttaaa tggtcaagag gaacaacgac gtggcaagaa gctaagagtc
    24841 ggtgacgtca tcaccattcc atcacagcac atcaagattg agcttgtagc gcctagtcag
    24901 gccgaaaaaa cagcctatga agctgaaaag gcagaaaaag agcgagttgc taagatggtt
    24961 aaacaaatga atcaacaggc taaaaaagca cagaccaagc aagcagctac taccaaaagc
    25021 aagcgtggtc aagctacctc agctgtaaaa gctaagtcta atcaccaaaa gcctattcgc
    25081 ttcccaggat tgtagcatgt ggatcaaaga actaaacctc acccattacc gtaattatca
    25141 acaagcctca gcagcctttt caccgggctt gaatgttttc attggtgaca atgcgcaggg
    25201 caagacaaat tttcttgaag ctatttattt tttgtcagta acaagaagtc atcgcaccaa
    25261 atctgataag gacttaatct actttgacga aagggattgc tctatatctg gaactcttga
    25321 gcgccttagt ggtcgtgttc agctagaaat actgctgtct gataagggac ggatcaccaa
    25381 gattaacacc ctaaagcaag caaagctttc tgattatatc ggagcaatga tggtggtcct
    25441 ctttgctcct gaggatctac agctggtcaa aggctctcct aatcttagac gaaaatttat
    25501 ggacattgac ttaggtcaga taaagcctgt ttacttatca gatttgtcac attacaatca
    25561 tgtcctaaag cagcgaaatg cctatctcaa aagtgttcat cagcttgata atgacttttt
    25621 atctgtgtta gatgagcagc tggttaccta cgggagtcgt gtaatggcgc atcggttggc
    25681 gtttgttcaa tcactagcaa aagaggcaaa caagcatcat caagctatct ctaatggcct
    25741 agagaagctt tcgatctcct atcaagcctc tgtgagcttt gagcaccagc aagagattta
    25801 tcagcaattc atgaaccagc tcaaaaccac tcatcaaaga gatttcttga gaaaaaatac
    25861 tggtgttggc ccccaccgcg atgatctggt tttttatatt aatgacatga acgctaattt
    25921 tgctagtcaa ggccagcatc gtagcctgat tttatcactg aaaatggcag aggttagtct
    25981 gatgaagcaa ttaacaggtg acaaccctat tcttctactt gatgatgtta tgagtgagtt
    26041 agacaatacc agacaaacaa agcttctggg agctgtcaag aaagaaaatg ttcaaacctt
    26101 tatcacaaca actagcttag agcatttgtc tcagctacct aaggacatta gtctctttaa
    26161 ggttaataaa ggaacaatag aacgagattc tatcatgatt gattaactga gcaaactaaa
    26221 aaaagggcac cttaatagtg acccttttta cggttaaatt agttgatact ctatgatttg
    26281 acgataccta agaggatagc gccaacaata aagcaaagga tacctgtaat gacccagcgc
    26341 atctcttttt tggtttttgt ctcacctaag aataaaatac ctccgacaat agagataata
    26401 gcgcccaatt gtgaaaagct aaaagcaatc gccagaccag cctttgaggc tgctagcagc
    26461 atgaagatat ttccaactcc ccaaagcaag ccaacaacac tatttttgat aacatactgg
    26521 tcaaacgata ccttaaacga cataaacatg gctgcaccaa gcaccattcc cactgccatc
    26581 ggtaaaataa ccgacaacac atcaaatttc ataatgttat tgaacagcac agcatacatc
    26641 acatagccgg ttgtcgagta ggttaaggct ctaaagccct ttgaaaaatc atgcaattga
    26701 ttacttgctg cattcgtctc gtcctgcttg cttgaaaaat aaaaaccaac aatcaaaaga
    26761 agtaaggcaa tcgtaccaac gacaaattga ataggcttgg tccactcatg aaagaccagc
    26821 acaccaatca ggctacctaa aactagctga gaaccactag acaagggatt tgctactgaa
    26881 acacccatat actgcatggc atgaaattgc ccagtctgac caacagacca gataatacca
    26941 cctaaaatcc caaaaatcca gagcttcata gacatctcag gtctgactac taaccaaaca
    27001 actagagcaa atagtaaagc tcctatggtc attccaaagg tctgctgtga gggtttaccg
    27061 ccaattttat tactaacaaa gccaatactt ccccatgcaa acattgggac aagtgcaaat
    27121 aaaatacctt ccaaatttac atctccttta caataagttg acacatgatg ttaacgataa
    27181 aagtgctttc atacggagaa ttattatagc ctatttcctt agaaaataca ataacatgat
    27241 gtaaaaaatc atctgctcac acgcttctcc ctaaaaaggt gtcaaagtag ctgacagagc
    27301 ttatttactg caatgctaga ggattattta atgaaaaccg tttgacctta tggctggctc
    27361 tagctggagc tttgttaggg acttttgtga cctgagttcc aaagcaatca gcaactagct
    27421 gactgaaata gcctaagcgt ttgaggagta gagcaagatg attaaccata gcactagctg
    27481 cttgaccgga catgcttgct tctatggtag ctttgacaaa ggatagctca acgatgattt
    27541 tatccagcag tctgccaacc atcttttgac tagtgatgat gtcatctaaa tcaagagcgc
    27601 tgtaaactcc tttttcgatc aatcgactga gatctccatg caagttttga agccgatgcc
    27661 ttgcggtatt gactcgctgt atcgtatcag tcaatgccgg tactagagga catacctcag
    27721 ctctggcaga agcaataccg gatcttatgc ggcaaggata taaagcaccc agatttcccc
    27781 aatagctcct tgtcgttgta gaggtttcat ctttgatttc tgttcgttca acataaaccc
    27841 tatctgaaaa acgtctctct aatactgtca cgatattctt aaagatattc acctcagtag
    27901 tccaataatc aagtgtatca aatagccttg aaaaggttga cgcataaaca gaggcaacct
    27961 ttctggaata gtcccgactc ttttgttcca cctgctcatc aaaggcttgg agaatatctc
    28021 tgacatcatc taaaagacct gttctttcta ggtaagcatc atagctgctt gggacacaga
    28081 cgacatcagc acttccttga aattgaccat tttttaggct gttgcctagc cagttatctg
    28141 tagctgtgac attttgtgat acccctagga tcagctcact ggtattgatt atcatttttt
    28201 ccagctctat gatatcctgt aattccacgc taaatacctc ttttaaggaa tcgctaatac
    28261 cgtcaacttt actttcacgt aaacccgttc cttcaaaggt cttatcactc tccttcaata
    28321 gctgacgact ggcctcatca ataatctgcc aagatttcaa aagtgtcgag cgaccgataa
    28381 tactatcaat ccagcctgac ttttcatgct gagcagatga ggcaagctga agcgattttg
    28441 tgtttaagct cgctaattct gaatcataca tggccagatt gaggcgatta ttattcacat
    28501 atgggatctc atcataggaa aagggatagt ctaggctagc cgaatgagac agcatatcaa
    28561 acaagtcctg ctgaccaact aatctctcca aagaactttg caggctatta aaagtatcgg
    28621 ttaggccatt tgtagcaagc agggctttga tgttttctga aactcgcttt ttcctctctt
    28681 caaaggagtc ttttatggca tcattttttg cctgacattt ttcagtaatg tggcgaatcg
    28741 tttgcaggtc gcctgatata gaggattgaa ggttttgtgc aaggttagtc aggacaccag
    28801 cattgatgac aatcgtttgc ttatcagaaa gcacaccgta ccgagccgat gttgacgaat
    28861 caaagtaatt tctaaagcct aagtacagct cctctacctt agtgtctaat cggttatcgc
    28921 tgtcaatatc aataggcaac aggacattag catgaacaaa ccggccattt acgtctgtca
    28981 tgttgccata ttgatcatac tgatagccat gccacatatg ctgtaagact atatcattga
    29041 ccttttttgt attgacaaca aagacctgac cgactgctcc ctccttttgg tcaaagccca
    29101 taccaatgat gtcatgcgga tccacatagt tgtaaatgcg gtcatgcaag agctttgcac
    29161 gttttctttg atactcatta agcacacgat aggtgttggg gccattgtag atatagactc
    29221 cagagatacg agataagttt ttatcactaa cagaggtaac accgtactga actgtcatgg
    29281 agcctagcga atgaccataa aactcaaatg ttgcgttagg gtattgcttt aatgtcttat
    29341 tggtaaaggt tgctgccttt cggagctgag ctgtcccttt agttggtgtc tggtccggta
    29401 aaagaatgcg catagccata ggcaaatcat tgcctaccca atctgcaacc acatctactg
    29461 ggtgtttctg ccactggtct gggccagtag agccccggta cagcatggtg acatgcttga
    29521 cctgagcata gtctgccttg gtaggatgag ggggaagctt gacatctgtc acgacatagg
    29581 cttgaaaacc tgatatcgaa tcctctatct gagacacata accgatggaa aactcagaat
    29641 tatcatcatc aattaaaact ggtgaaccta ctgtatgttt ttcatactct tcctcagcaa
    29701 tccgttgtct ctgttcgtct gtcaggatca tcattttcac tctcctttta gtagtttttc
    29761 taacttttct gagcgataat tactagcgat ctctaaattt ctttctaaat catatctact
    29821 aaggcgaacc cttaaataag tatctggatc atcattgata atcaggtgaa tagaaaaacc
    29881 tcccattgga ttaata
//
LOCUS       DARYLJ010000029        29635 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYLJ010000029 DARYLJ010000000
VERSION     DARYLJ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29635
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(269..617)
                     /gene="ssrA"
                     /locus_tag="TU746_001168"
     tmRNA           complement(269..617)
                     /gene="ssrA"
                     /locus_tag="TU746_001168"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            708..1319
                     /locus_tag="TU746_001169"
     CDS             708..1319
                     /locus_tag="TU746_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0891518.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            complement(1366..2160)
                     /locus_tag="TU746_001170"
     CDS             complement(1366..2160)
                     /locus_tag="TU746_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891519.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(2170..2868)
                     /locus_tag="TU746_001171"
     CDS             complement(2170..2868)
                     /locus_tag="TU746_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891520.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            complement(2868..3239)
                     /locus_tag="TU746_001172"
     CDS             complement(2868..3239)
                     /locus_tag="TU746_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0891521.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            3481..6591
                     /locus_tag="TU746_001173"
     CDS             3481..6591
                     /locus_tag="TU746_001173"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL0891522.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            6671..7684
                     /gene="pfkA"
                     /locus_tag="TU746_001174"
     CDS             6671..7684
                     /gene="pfkA"
                     /locus_tag="TU746_001174"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL0891523.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            7746..9248
                     /gene="pyk"
                     /locus_tag="TU746_001175"
     CDS             7746..9248
                     /gene="pyk"
                     /locus_tag="TU746_001175"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL0891524.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            9377..9934
                     /gene="lepB"
                     /locus_tag="TU746_001176"
     CDS             9377..9934
                     /gene="lepB"
                     /locus_tag="TU746_001176"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL0891525.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            10111..11922
                     /gene="glmS"
                     /locus_tag="TU746_001177"
     CDS             10111..11922
                     /gene="glmS"
                     /locus_tag="TU746_001177"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL0891526.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            12106..12441
                     /locus_tag="TU746_001178"
     CDS             12106..12441
                     /locus_tag="TU746_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL0891527.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            12548..13189
                     /locus_tag="TU746_001179"
     CDS             12548..13189
                     /locus_tag="TU746_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0891528.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            13199..13828
                     /locus_tag="TU746_001180"
     CDS             13199..13828
                     /locus_tag="TU746_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0891529.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            13845..14681
                     /locus_tag="TU746_001181"
     CDS             13845..14681
                     /locus_tag="TU746_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0891530.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(14777..16015)
                     /locus_tag="TU746_001182"
     CDS             complement(14777..16015)
                     /locus_tag="TU746_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL0891531.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(16118..17452)
                     /locus_tag="TU746_001183"
     CDS             complement(16118..17452)
                     /locus_tag="TU746_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL0891532.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(17581..17667)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            17932..20223
                     /gene="pcrA"
                     /locus_tag="TU746_001184"
     CDS             17932..20223
                     /gene="pcrA"
                     /locus_tag="TU746_001184"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL0891533.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
     gene            20636..20881
                     /locus_tag="TU746_001185"
     CDS             20636..20881
                     /locus_tag="TU746_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL0891534.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            20929..21510
                     /gene="amaP"
                     /locus_tag="TU746_001186"
     CDS             20929..21510
                     /gene="amaP"
                     /locus_tag="TU746_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL0891535.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            21520..21708
                     /locus_tag="TU746_001187"
     CDS             21520..21708
                     /locus_tag="TU746_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL0891536.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            21721..22260
                     /locus_tag="TU746_001188"
     CDS             21721..22260
                     /locus_tag="TU746_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0891537.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            22298..22495
                     /locus_tag="TU746_001189"
     CDS             22298..22495
                     /locus_tag="TU746_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL0891538.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            22505..22993
                     /locus_tag="TU746_001190"
     CDS             22505..22993
                     /locus_tag="TU746_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0891539.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            23149..23790
                     /locus_tag="TU746_001191"
     CDS             23149..23790
                     /locus_tag="TU746_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0891540.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(23907..24455)
                     /locus_tag="TU746_001192"
     CDS             complement(23907..24455)
                     /locus_tag="TU746_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0891541.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            24578..25279
                     /locus_tag="TU746_001193"
     CDS             24578..25279
                     /locus_tag="TU746_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891542.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            25291..27930
                     /locus_tag="TU746_001194"
     CDS             25291..27930
                     /locus_tag="TU746_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL0891543.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILTSHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            28006..28602
                     /locus_tag="TU746_001195"
     CDS             28006..28602
                     /locus_tag="TU746_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0891544.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            28612..29574
                     /locus_tag="TU746_001196"
     CDS             28612..29574
                     /locus_tag="TU746_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL0891545.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         8650 a         5338 c         6821 g         8826 t
ORIGIN      
        1 gtaaatgatg tctatataac aggcaataca gggcaattat ccgaaaaaat ttgataatgt
       61 gctgtcaatg aagcaagtag aagaagtatt ataaaaaaat aaatataaga ttagctaaag
      121 agaaaattca agctgttctt aaaggatttt ttggcctttt ttttgctatc actttcatag
      181 aaacttacgg taacccacga acaggacaaa aagaaaaaac cttgatttaa caaggtttta
      241 gtaagttatg gtaacttacg gtaagtattg atggagctgg tgggagtcga acccacgtcc
      301 aaacacctgc taacctattt gtctacaacc ataggttatg tcttacttta acagaccaag
      361 gacacataac tcaagccatc agcctgcgag tctagggttc tctttttagg tgactagaca
      421 atcacctaaa cgtagcttgc tgttttgaga cctctaataa gacacaagca atcctataga
      481 agtcacgccg gctggttttt aggcagctaa agcgtaagtt gtgttatttt ttgcagttat
      541 atttaactgg catttttaca tctgccgatg agttgcaaaa taggcctcat aatgcctgtc
      601 gaatccgtaa caaccccata aaaaggcgta tgagatactt acggatgcta gtatagcaaa
      661 atttttttaa aatggcaaaa aaatagcgct tatggtatga tgaagctatg agaaataatg
      721 agttgaagcc ttatgtgata tggcaaaaag tgattaagct attaggaagt ctggctttag
      781 tcggatcttt tttgctagcc ttttggtttt acaggcttgg cattttaaat gacagcaatg
      841 cactcaagga tcttgttcat agtcacaagg tttttggccc ccttgttttt gtcggtgtgc
      901 aaattgttca gattgttttt cctattattc caggtggtat gacaactatt gcaggctttt
      961 tgatttttgg ccctttgctg ggttttcttt ataactatgt tggtatcttc attggtagtg
     1021 tgattctgtt tttacttgtg aagacctatg gtaggcgctt tattttactg tttatagagg
     1081 aacagacctt ttacaagtat gagagaaaat tagagatgcc atattatgag agattgttta
     1141 ttctctgtat gctttctccg atttcaccag cagatattat ggtcatgatt actgggctga
     1201 cagagatgtc gttgaagcgt tttgtgacca ttattttaat cacgaagcca ctatcaatta
     1261 ttggctacag ctatcttttt atctttggaa aggatttgat cctatggttt ttccattaaa
     1321 aaagtctagg cattgcctga taagcagtgg ctagactttt tgttatcatt ggatattaag
     1381 cttgtttttg atgatgaagt gagtagcaac gtaaaggata atgccttcaa ctagttgctc
     1441 tatgtttaaa atagatatgg ctgtatgatc accgaaatag agtagcgagt ctgagctatt
     1501 tgggttgacg gtgaaaaacg catcatttaa ataagtcatg acgacaataa tgataataac
     1561 taaaatgaaa taggcacaaa atgccatcaa accacgacga tttgaaaata gctgaccaat
     1621 tgagattgct agataaatca atagtatact tgttatggtt gacaaaagca tgtagatgag
     1681 gatagaagca ttttcgacta agttttctgg cttcataatt gtctttagca cctttagtag
     1741 ataggtaaag tcaactgttg gcgctattaa aataaagata ccgattaata ggttaatgcc
     1801 attaaaaata ctgcaaacaa aggacgctaa cagcttggac aagataatct gatgtgctgt
     1861 tactggtagt gtcagtgtta agtatccctc gcgcccaaag acatttttgt taaagcgatt
     1921 aatgatgatt aatagcgttg ataagaatga tccggcaatc agagaaccaa acgttaatga
     1981 gagtgtgaga ggaaccattt tgtttgccag acttgttgtt aaaccaacct cgtcaggatt
     2041 gtttgtaagc gtattgatgg taaaagaaag gactatcgcg atagcaatga caccggcatt
     2101 aagcgcaaaa taccacttgc caattgatct aaattcgtat tttaataatt ttccaaacat
     2161 gcctacctcc taaaccttgt agatctctct aaataatgaa tcaatcgatt gctgatgctg
     2221 aactcgtaaa tcatcagcgt ttccagaaag gcagagctta ccatttttta agaaaatagc
     2281 ttcatcaagt acaggctcaa tgtctgagat gaggtgagta gaaatgataa cagaggcttg
     2341 ctcagagtaa ttattaataa tggttttaag aatataatct cttgctgccg ggtcaacccc
     2401 tccgataggc tcatcaagga tatagagctt tgctttgcgg ctcatcacga ggataagctg
     2461 tgccttttcc ttatttccct ttgataggtt tttaaagcgc tcttcagcat ctaagtctaa
     2521 atccttcagg agactggtcg ctttatctct gtcaaaatcg gcatagaaat caccaaaaaa
     2581 gtctagcata tccttgattt tcatactttc attaagatag gtcgtatctg gtaagtaaga
     2641 aatgattttt ttagtttcta cagatggtct aaagccgtca ataacaatgt ctcccttgtc
     2701 tggctgtaaa agtccgttga ttagcttaat tagtgtagtt ttgccgctac catttggtcc
     2761 tagtaagccg ataatttttc cagaagggat tgttatggtt aaatcatcaa tagctaattg
     2821 ttttttgtaa gattttgaga cgtggtgcag ctgtaatagt tgtgccatta gtttgatccc
     2881 tcctctaaaa aggtacttaa aacaggaatg atttctgaac gttcaaaacc tattttgatc
     2941 atattgctaa taaaggactt gagctcgttg atggccagct ctcgtctttt gcgcgcgata
     3001 agctcttggt tatctgttac aaaccggccg gcagttcgtt gcgagtaaac tatgccttca
     3061 cgatctaatt cggtaagtgc tctttgcatg gtgttgggat taacgccggc aatttcagca
     3121 tattctcgga cagtcggcag ctgatctcca cttttgatct cttggctgac aatttgcagc
     3181 atgatatgct gtgctatctg tgcgtaaata ggagatttct catcaaattt ccaagacata
     3241 ctgtctcctt tctttctaaa atctgcgatt aatatttgta ctaattaaat gatacaaaaa
     3301 aacgattgac ttgtcaagcc ttgtgtgtca tctctagtta catactggct tgcaatgcta
     3361 gtgggattcc tgctgatagt ggtgcagtaa agacagatca ctgctattaa aagcttaaaa
     3421 tctgggcagt aaagtctttt tcatagtata atggtagtaa gaacgctaaa ggagatgtcc
     3481 atgtttgctc agttagatac aaaaacagtt tattccttta tggatagttt gattgattta
     3541 gaccattatt ttaaacaagc caaacgatta ggctatcaag ccatagggat tatggatcag
     3601 gataatctat atggggcata tcattttatt aagggctgtc aaaggcatgg gcttcagccg
     3661 attttaggtc ttgaggtggc tattacagtt aaagagcagg ctcttacgct gaagcttgtt
     3721 gcgaaaaatg atacaggcta tcagcagctc ttaaagcttt cgactgaaaa aatgtctgga
     3781 gacctagacc tagacacatt ggtgcagtat ttagaaggga tagcagttat cgttcctttt
     3841 agtcagagct tgcgtgattt agggcttcct tttgattact tcattggcat tgatgaggca
     3901 agcgacttgt caaagataga ctctacagaa agactgattc cgcttagaac ggtacgttat
     3961 tttgataatg ctgagactga gactctgcaa atgctgcatg ccattcgtga taatattagc
     4021 ttagcagata cggctctagt agccaaggat cagtttttag cgccttgtca ggagatgacg
     4081 gctattttcc aggaaaagtg ccctgaggct ttggtgaatc tcgtaaatct aacagcttcg
     4141 attgcttatc attttgatac tgatttaaag cttccgagat ttaaccgcga taagccagca
     4201 aaagaagagc taagagaatt gaccgagtct ggtctaagag aaaagcaatt atggaaggag
     4261 ccttaccaat ttcgtctggc agaggagctg gctattattt cagatatggg gtttgatgat
     4321 tattttctca ttgtctggga tttgctgcgc tttggaagga gtagaggcta ttatatgggc
     4381 atggggcgtg gttcagcagc aggcagtcta gtggcttatt cgttgcgcat tactgggatt
     4441 gatcctgtca aaaacaattt attgtttgaa cgctttttga ataaagaacg ctacagcatg
     4501 cctgatattg atattgattt gcctgatatt taccgctcag agtttcttca ttatgttcga
     4561 gaccggtatg gtagtgagca ctcagctcag attgttacct tttcgacttt tggtcctaag
     4621 caggctgttc gtgatgtgtt caaacgcttt ggtgtcccag aatacgagct aacaagccta
     4681 actaaaaaaa ttgggttcaa ggataccctg agcactgttt atgagaaaaa tatagccttc
     4741 agacagacca ttaatagccg cttagagttt caaaaggcat ttgagatagc taagcgcatt
     4801 gaaggcaatc caagacagac ctctattcac gctgctggta tcgtgatgag tgatgaccat
     4861 ctgaccaacc atattccctt aaaaaagggg gaggatatga tggtgactca gtatgatgcc
     4921 agtgctgttg aagctaatgg cttgctgaaa atggattttc ttggtctgag aaatttgacg
     4981 cttgtacaga aaatgcagga aaaggtggtc aacgattacg gtctttcaat tgacattgaa
     5041 gctattaacc tagaggatcc tgaaacgata gccttgtttg ctaggggtga taccaagggc
     5101 atttttcaat ttgaacagca tggtgcgatt agcctgttaa aacggatcaa gccgactagc
     5161 tttgaggaaa ttgttgcgac aaccagctta aatagaccgg gagcaagtga ttacacgcag
     5221 aattttatta agcgccggca gggacaggaa aacattgatc taatagatcc ggtgattgct
     5281 ccgatattag agccaaccta tggtatcatg ctttatcagg agcaggttat gcagattgct
     5341 caagtttatg caggctttac acttggaaag gccgatttgc tacggcgtgc tatgtctaag
     5401 aaaaacctcg ttgagatgca aagaatgcag gaggattttc tgactggtgc tagagccttg
     5461 ggtcgctctg aggagacagc cagactattg tttgcacgta tggaaaaatt tgcaggctac
     5521 ggctttaacc gcagccatgc ctttgcttat gctgccctag cctttcagct agcctatttt
     5581 aaagcgcact atcctgaggt attttttgat gtcatgatga attattctag cagtgattac
     5641 atcacagatg cgttagattt tggctttgag gccgcgcagg tgacgataaa caccattccc
     5701 ttcaatgata agattgagcg tcataagatt tatatgggct taaaaaacat caagggtctt
     5761 cctagagaat tttcgtattg gatcattgaa aataggccct ttaccagtgt tgaaagcttt
     5821 ttgtgcagca ttcctgaaaa ataccagaaa accagcttct tagagcccct tatcaaaata
     5881 ggcctgtttg atgggtttga aaaaaatcgc caaaaaatca ttaacaactt agaaggactg
     5941 ctaacctttg tcaatgaatt gggatcactt tttgcggatt cctcctttag ctgggtagag
     6001 actgaggatt attcagctgc tgagaaatat tactttgagc aggatttgct tggtgttggc
     6061 atgagcaagc accccttgct agctgtcgct gaaaaaagca cagtagcagt cacaccaatc
     6121 acaaagttag tgaaggatac agaagctact ttgctggttc aaatagatgc gatcagggtt
     6181 attcggacaa aatcaagcgg acagcagatg gcctttttga gtgttactga taccaaacag
     6241 aaattagatg ttaccctttt tcctgagcaa tatgctgtct ataagcaaga cctaaaagag
     6301 gggcatattt actatatcaa tggcagggta aaagaaagag ataaccgctt gcagctagtc
     6361 tgtcaccagc ttcgattagc tcagagtcaa aggtattggc tattggttga aaaccatcag
     6421 catgatgctg ctatttctga catattaaca gccttttcag gggagactcc tgttattatc
     6481 cattatcaag aaggcaaaga aaccttagag ttaaaccata ttagggttga tgttagtaag
     6541 gatttggagg aggctattag cccctacgtg ttgaaaacgg tttttcgata aaaatagcga
     6601 attagtgaag taatttgcaa acgaatgtgc tataataaaa acgttaaatt aattaaagga
     6661 gtaccaaaaa atgaaacgta ttgctgtttt aaccagtggt ggtgacgccc ctggtatgaa
     6721 tgctgctatt cgtgcagttg ttcgtaaagc aatttcagaa ggaatggaag tctatggtat
     6781 taaccgcggc tatgctggta tggttgatgg tgatatcttt ccactaggct caaaagaggt
     6841 tggtgataag atttctcgcg gcgggacctt cctttattca gctcgctacc cagagtttgc
     6901 tcagcttgag gggcaattgg ctggtattga gcagctaaaa aagcatggca ttgaaggggt
     6961 agttgtcatt ggtggtgatg gttcttacca tggtgcgatg cgcttgactg agcatggctt
     7021 ccctgcagta ggtatcccag ggacgattga taacgatatt gctggaacag actatactat
     7081 cggatttgac actgcggtca atactgcggt agaggctatt gataagcttc gcgatacctc
     7141 atcaagtcat ggacggacct ttgttgttga agtgatggga cgcaatgcag gtgatatcgc
     7201 actttgggca ggtattgcaa gtggagcaga tcaaatcatc gttcctgaag aggaatttga
     7261 cattcataaa gtggtctcaa caattaaaga cgattttgaa aatagaggaa aaaatcacca
     7321 tattatcgtt ttagctgagg gtgttatgag tggcgaggcc tttgcgcagc agctaaaaga
     7381 agctggagat gaaagtgacc ttcgtgtgac aaaccttggt catatccttc gcggtggctc
     7441 tccaactgcg cgtgatcgtg tgattgcgtc atggatggga gcgcacgctg ttgagttgct
     7501 caaggaaggc aaaggtggct tggctgttgg tattcataat gaagagcttg ttgaaagtcc
     7561 gattcttgga agtgcagagg acggtgcctt gttcagcctt actgatgagg gtaacattgt
     7621 tgttaataac ccgcacaagg ctcgcttaga ctatgctgct ttgaaccgtt cattagcaca
     7681 ataggataag taagatctgg taatctttgt taatcaacta aaaaataagg gagtttcata
     7741 ataaaatgaa taaacgtgta aaaattgttg caacacttgg tcctgcggtt gaaattcgcg
     7801 gtggtaaaaa atatggtgag gacggctatt gggctggtca gttggacgtt gaacaatcag
     7861 ctaaaaagat cgctgaattg attgaagcag gtgctaatgt tttccgcttt aacttctcac
     7921 atggtgacca caaagagcag ggtgaccgta tggctactgt tcgtcttgct gaaaagctgg
     7981 cacgtcaaaa ggttggtttc cttttggata caaaaggacc agaaatgcgt acagaattgt
     8041 ttgctgacga tgccaaagaa tatagctatg tgactggtga gcgtattcgt gttgcgacag
     8101 cacaaggcat tcaatcaact cgtgatatga ttgccttgaa tgtagctggt gctcttgata
     8161 tttatgatga ggttgaggtt ggccacacta ttcttattga cgatggaaag cttggcttaa
     8221 aggttatcga gaaggacatt gcaaagcgtg agttcatcgt tgaggttgaa aatgatggca
     8281 tcattgcaaa gcaaaagggt gttaatatcc ctaataccaa gattcctttc ccagccttag
     8341 cagaacgtga taatgctgat attcgttttg gtcttgagca aggtcttaac tttattgcta
     8401 tttcatttgt tcgtactgcc aaggacgttg aagaggttcg tgagatttgt cgtgaaacag
     8461 gcaatgagca tgttcaatta tttgctaaaa tcgaaaacca acaaggtatt gataaccttg
     8521 atgaaatcat cgaagctgca gatggtatca tgattgctcg tggtgatatg gggattgagg
     8581 tgccatttga aatggttcca gtcttccaaa aaatgattat caccaaggta aatgcagcag
     8641 gtaaagcagt catcaccgca actaacatgc ttgaaacaat gactgaaaaa ccacgtgcaa
     8701 ctcgttcaga ggtatctgac gttttcaacg cggttattga cggtacagat gcgacaatgc
     8761 tttctggtga atcagcaaat ggtaaatacc ctgttgaagc agttcgtaca atggctacaa
     8821 ttgataaaaa tgcacaaact cttcttaatg agtatggtcg tttagattca tctgccttcc
     8881 cacgtaccaa taaaactgac gtgattgctt cagctgttaa agatgcaaca cactcaatgg
     8941 atatcaagct tgttgtgacc atcactgaaa caggaaacac agctcgtgcc atttctaagt
     9001 tccgtcctga tgctgacatc ttggctgtga cctttgatga aaaggttcaa cgtgccttga
     9061 tgattaactg gggtgtgatt ccagtgcttg ctgaaagacc agcatcaaca gatgatatgt
     9121 ttgaggtagc agagcgtgta gctcttgaga ctggtttggt gcaatcagga gataatatcg
     9181 ttattgttgc aggtgtgcca gttggtacag gtggtacaaa tacaatgcgt gttcgcactg
     9241 taaaataata gctttccata agctttagct attttgctct atcagataat ttaaggcaaa
     9301 caatgatact taaaaattgt ttgctttttt tattagtcat atcatgttat aatgagacta
     9361 tagactagga gttattatgg taaagcgaga ttttataaga aatatattgt tgttattgat
     9421 tcttattgtg ggagctgtcc ttcttagaat atttgttttt tcgacctatc gagtcacgtc
     9481 agaggcttca aatgcctatt tgaataaggg cgatttaatc accattaaga aaaatattga
     9541 gcctaaatat aaggattttg tggtttatac ggttgacaaa aaggattatg tgagccgggt
     9601 tgtagcagta gcaggtgatc gtgttaccta tatggacgat attttttacc tgaacaatat
     9661 ggttgaatcc caatcctacc ttgagagtat gaaggcaaag tatctcaatc atgcccctat
     9721 tggtacgctt tatacggagg attttacgat ttcgacggtt acttctggaa aatacgatag
     9781 cattcccaag gggaaatacc ttttgctaaa tgataacaga aaaaaccatc atgatagccg
     9841 tcagtttggc ttaattgacg tgtcacaaat taagggatta gtaacattta gagtgcttcc
     9901 tttgaaagac tttggatttg tagaggtaga gtagctttaa ggctgctcta ttttgtttct
     9961 caaaatatga ctataccaat tttcttgttg acaagatttt tctgaagtta tatactctaa
    10021 atataacgtt ttagtcggtt tatatctgac tataccaatt atattgatca ttaaagaaag
    10081 tagtaagcta gcttactgag gtgttaagtt atgtgtggaa ttgttggagt tgtaggtagt
    10141 cgtaatgcga ctgacatctt gatgcaggga ttggaaaaat tagagtatcg tggttatgat
    10201 tcagctggta tttttgtgtc agatggcagg acgtccaatt tggtaaaatc tgttggacgc
    10261 attgcagatt tacgctctaa gattggcatt gatgttgttg gaacgaccgg tattggtcat
    10321 acacgttggg caacgcatgg tcaagcaaca gaggaaaatg ctcaccctca tacctctcag
    10381 acaggtcgct ttgttcttgt tcataatggt gtgattgaaa attacctcca gatgaaggag
    10441 cagtaccttg ctggacacac gtttaaagga caaacagaca ccgaaattgc agttcatttg
    10501 attggagcat ttgttgaaga aggctgttca gtcttagagg cttttaaaaa ggctttatca
    10561 atcattgaag gctcctatgc ctttgctttg attgatacag aggatatgga tacgatctat
    10621 gtcgctaaga ataaatcccc attgctgatt ggccttggtg agggctataa catggtttgt
    10681 tcagacgcta tggccatgat tcgtgaaacc agcgaattta tggaaatcca tgacaaggag
    10741 ctggttatcc tgacaaagga ttcagcaagg gtgacagatt atgctggcaa tccgattgat
    10801 cgtcagtcat atacagcaga gcttgatctt tcagatattg gcaaggggac ctatccattt
    10861 tatatgctaa aggaaattga cgagcagcca acagtgatgc gtcgcttgat ttcaacctat
    10921 gcagacgcca agggacagat gatgattgat ccagctatca taaggtctgt ccaagaggct
    10981 gatcgtatct atattcttgc agctgggacc tcttatcatg ctggctttgc ttctaagtca
    11041 atgctggagc atttgactga tacacctgtt gaattagggg ttgcttctga gtggggctac
    11101 aatatgccgc tattgagcaa aaagccaatg tttatcctct tgagccagtc cggtgagaca
    11161 gcagatagcc gtcaggtttt ggtcaaggca aatgagatgg ggattccaag cctaacagtg
    11221 acaaatgttc ctggctcaac cctatcacgt gaagcaacct acactatgct gctccatgca
    11281 ggtccagaaa ttgcagttgc atcaactaaa gcctacacag cacaggtcgc tgcacttgcc
    11341 tttctagcta aggcagttgg tgaggctaat ggcaagaagg aagctattag ctttgatttg
    11401 gttcatgaat tgtcattggt cgctcagtct attgaggcca ccttatctga caaggagctg
    11461 attgctgaga aggtgcagac cttattggca acaacacgca atgcgtttta cattggtcgt
    11521 ggcaatgatt attatgttgc tatggaggct gcactaaaat taaaagaaat ttcatacatt
    11581 cagtgtgaag ggtttgcagc tggtgagcta aagcatggga ctatttcact gattgaggat
    11641 ggcacacctg ttattggact tatttcttca agtgagctgg ttgctgcaca tacacgtggc
    11701 aatatccaag aggtggctgc acgtggcgct catgtgttga cagttgttga ggagggctta
    11761 gagcgtgagg gagatgacat tattattaat aaggtgcacc cattcttagc gccgattgct
    11821 atggttattc cgactcaatt aattgcttac tatgcttcct tgcagcgtgg tttagatgta
    11881 gataagcctc gtaatttagc caaggctgtt acagttgagt aatagttgcc tgcttaaaat
    11941 gaggcagcag ggtcctgaag cctatttgaa acgagcttga catgatgtta tgtcaggctc
    12001 gttttttagt gcttgcctgg tcttatgata acgtattcat cttgtcaaat aagcatttct
    12061 gaagtaaaat attaacgtta agactaagaa gcttaggaga gtaagatgac gttaccaaat
    12121 tgtttacaat gcgattcaga atatgtttat gaggacgggc atttgctcat ttgtccgatg
    12181 tgttcctttg aatggacacg tggtgaggag gagcctgagg aggaggggct tgtcgtttta
    12241 gatagtaatg gaactagatt agctgatgga gacactgtta cgatcattaa ggacctgaag
    12301 gtcaagggag cgccgaagga tctcaagcag ggaactcgtg ttaagcatat tcgtcttgtt
    12361 gaaggtgatc acaatattga ttgtaagatt gatggctttg gtgcaatgaa gctaaaatca
    12421 gaattcgtca agaagattta ataacaataa gcaaccagat gactggttgt atttttatag
    12481 aaaagtactt ttcaatccat cagaaaattt ggtataatgg ataaactatt tatatctagg
    12541 agacaacatg acgtatatta tgcaggtttt acccagcttg ctggatggtg ccttaatcac
    12601 tttacaggtt ttctttattg taattgtatt atccattccc ttaggggctc ttttagcttt
    12661 tttgatgagg gttgacttta agcccttgca gtggctattg acgctctata tttgggtcat
    12721 gaggggaaca cccttattgt tacagctcat ctttttttat tatgttttgc caagtgtggg
    12781 tgttaccttt gatcgtatgc cggcagcgat tttggctttt accttaaact atgctgctta
    12841 ttttgccgag atttttcgtg gcgggataga gactattcca aatgggcaat atgaggctgc
    12901 aaaggtgctg aagcttagtc cggtacaaac tgttcgctat gttatcttgc ctcaggtgtt
    12961 caagattgtt ttaccaagtg ttttcaatga ggtgattaac ttagttaagg attcttcctt
    13021 ggtatatgtg ttaggagtag gggatttgct attagcaagc aagactgcgg caaatagaga
    13081 tgcaacctta gcaccgatgt ttattgcagg tttgatttat ttgctcttaa ttggtttggt
    13141 caccatttta tcgaagcagg ttgaaaaaag atttaattat tatcagtaag ggggtcatat
    13201 gttagaactg aacaatattt caaagcgatt tggtcacaag cagatctttg atggctttca
    13261 tttgaccgtt gaagatggtg aggttttatc tttggtaggg ccatctggtg gtggcaagac
    13321 tactctgctc cgaatgctgg ctggcttaga gcctattgat tcgggaaata ttagctataa
    13381 tggcgagtct gttcctattg atcatttaga aaaaagaagc ctgcttggtt ttgtttttca
    13441 ggatttccaa ttgtttccac atttgacggt gctggataat ctcatcttgt ctcctaccat
    13501 taccatggct atgccaaggc ctgatgcaaa gcaaaaggct atggagctgc tggagcgcct
    13561 aggtctcaaa gagcatgcag ctgcttatcc ttatgcgcta tctggtgggc aaaagcaaag
    13621 agttgccttg gctagagcga tgatgattga cccacagatt gtaggctatg atgagccgac
    13681 aagtgcctta gactctgaat tacgtcagga ggttgagaaa ttgattttgc aaaatcgtga
    13741 gatgggcatt acccagattg ttgtcaccca tgatttgcag tttgctcaga ccatttctga
    13801 tcgtatcatc aagatcaatc ctaaatagaa gaagaggtag tgctatgacg ttaaaaaaga
    13861 cccttctagt agccctattt gctgctacag ctacgctttt agtagcttgt ggcgctagta
    13921 ataaacagac tagctcagat gcttgggatt cctacaagca gaaaaagacg attacgcttg
    13981 gctttgataa tacttttgtg ccaatgggct ataaggacga gtcaggaaaa aataccggct
    14041 ttgatattga gctagcaaag gctgtttttg accaatatgg tatcaatgtt aagtatcaag
    14101 ccattaactg ggatctcaaa gaaactgagt tgaacaatgg taaaattgac ctgatttgga
    14161 atggctattc tgtgacaaaa gagcgccaag ctaaggtggc ctttacagag ccttatatga
    14221 aaaatgagca agtcttagtg acgcaaaaat catcgcaaat aagctcattt gctgatatga
    14281 aaaataagac cttaggtgcc cagtctggct catctggcta tgatgccttt acgagtcatc
    14341 ctaaggtgct aaaggatctt gtcaagggaa atgacgctac ccaatatgaa acctttacac
    14401 aagcctttat cgatttaaaa aacaagcgta ttgatggcct tttgattgat agggtttatg
    14461 ccaattatta ccttcagcaa gaaggtgagc tagaccgcta taacattatc gcgagtgagt
    14521 ttgaaggtga ggattttgca gttggtgtcc gaaaagcgga taaaacccta caaaaaaaga
    14581 ttacacaagc cttaaaatcg ctttatcagg acggtacctt ccaaaaaatc tctaaaaaat
    14641 ggtttggtga agatgtcgca acagttcagt tgaaatcata agacgcaagc aagacctaat
    14701 cagctcagag gggttgagac tagatacatt taaaagactt accttctaaa ggcaagtctt
    14761 tttatacggc ttattattag ctgatacgct tgatatgata gtgtttttta attgctatgg
    14821 agtttgttat tggtgtgatt tgatgatata tcaggtgcca agcttcgtgt cgtctccaga
    14881 tactggtatg ctgattgccc tgtagctgat aggtgactag cttggtgttg tggctgatgg
    14941 attgcataca aaaggcttca agctgattgg aagaagaacg ctgctgctct aaaaattgct
    15001 tggcattgta agcttgtcca tcgcgatcaa taaaggtaaa ggtcttggca atgagctctt
    15061 gataatctgg gatttgactt agcatgattt tctcgttttt gtagagcttt ttgtaaacat
    15121 attcacagtt gtcatcttta ggaagctttg caggctcaac atgaatatca atatcataaa
    15181 cagcaaattg ctcactcaag agctgttcga cctgctcggt tatggcgtga ctttcataaa
    15241 cagaaaggtc agggtgcatc tcaaggacaa tatctaaata gacattgctt ccgtaagtgc
    15301 ggccgcgctg tgatttgaca gcaatgattt tgggaatttt caatatggcc ttttcatatg
    15361 ctttgagctg cgtgctgtca aagccatctg ataagctaaa ggcgcttgcc ataaaaatat
    15421 caaaggctgt ttttagaatg aaaaaggtaa tgataagggc agccagccta tcaataatag
    15481 gtagctttaa ggaagcggcg ataatagcaa tagaggttcc aatagaggtc acagcatcag
    15541 aaagattatc tttagaggct gcaaccaagg cactggatct tacctttttt gataacgctt
    15601 tattaaaagc atatactcca agcatcacaa gggctgaagc gatcccaaca atagcaccta
    15661 atggatcgat agcagactgc ttaccactaa tcatctgttg aatagtttgc aggagaacct
    15721 gaaagccaac aatgaacatg ataaaggagg ttattaagct tgaaaggtct tcgattttcc
    15781 agtggccaaa gcggtgattg gcgtctgctg gctggctggc cagatgaagt ccgatgagca
    15841 gagtgacatt accaacgata tcagacaggt tgttgaagcc atcggcaatc aaggagctgg
    15901 catttaaaag atagccagca agaagctttg tgatgctaag ggccaaatag gtaacaatgc
    15961 taacaatggg ccctcttttt gctaaccgaa ggttttctac tggattgttt ggcataaaaa
    16021 ctcctttgta actgatgctt tcattatatc ataaaagcta agacaagcta aaagcctaga
    16081 gctatcctaa atagggtatt ccaggctttt cgatagctta tttggtgctt tggcgcttaa
    16141 aatatgccct tgtctcaaaa atgacaacag gagataaggc tagtagggcg ataagatttg
    16201 gcagagccat caggccattg acaatatctg ccagtatcca aatcaactcc agcttaagaa
    16261 agccaccaag tcctaccatg ataacaaaga tcaggcgaaa atagctgagg tgtgtcgtgc
    16321 caaataaaaa gataaagcag cgctcaccat aatagctcca gccgagaata gtcgtaaaag
    16381 caaaaagaac aagcgacagg gtcaaggcat aggtgcccat atgcccaaag atagaagcaa
    16441 aggcagactg tgttaagggt gctccctcta gtgcgctagt ccactgacca gttaccaaaa
    16501 tggccagacc agtcagagtg cagatgatga tcgtgtcaat aaaggttccg gtcatagaaa
    16561 tcaggccctg ttctactggc tccttggttt tagcggcagc agcagcgatc ggagcagagc
    16621 ctagtcctga ttcgttagaa aaaaccccac gtgcaatacc cttttgaatg gcgtccttaa
    16681 ccaagcttcc ggcaaagccc cctatagctg ctgtaggggt aatagcggac ttaaagataa
    16741 ggacaagcat aggaagaagc ttagtatagt gaacagcaat aaccgttaag cttgctccaa
    16801 tataaaagat agccatgaaa ggaacgactg tttcagccac cttggcaata gcttgaatgc
    16861 ctccaaaaat aatcatggcc acaacagcag ctagcaagac actgattaat ggcgaagaga
    16921 tcccaaggct atggtgtagg gatgaggtaa tcgcattgac ctgagcaaat gtcccgattc
    16981 caaacaaagc cactaaaata ccagagacag caaataagtt ggctagaggc ctccattttt
    17041 gccccatacc atttaaaatg tagtacatag gtccgcctga aatctgacca ttagcgtcct
    17101 tagtacggta tttaatggct aaaacgccct cggaatattt ggttgccata ccaaagaagg
    17161 cagcaaccca catccaaaaa agtgccccag gtccaccaga ctttatagcg gttgcgacac
    17221 caacaatatt accagtacca actgtagcag ctagggctgt tgctagagca gcaaatgatg
    17281 aaatatctcc ttgcccctca ttcttagcaa aaatgagcct aaaggcctta ggcaacttga
    17341 tgacttggag aaggctaagt ctgctggtga ggtaaatgcc agtaccaagc agcagtagca
    17401 acaagggtgc tccccaaacc aaatcgtcta tccattttgc agcagctatc atgcttaatt
    17461 cctcaactct cttaaccaat gctgccaaaa gaaaaagcca cccctgcgga tagcctctga
    17521 agcatatgac aaaacagcaa gcacaaaaaa tgctaaggaa gcatgatcat acggcttgat
    17581 attttatctt ctgtcctttt gcctgagaga ttgagcagtc ttgccttgcc ccttcggcgc
    17641 ctaataggtc tctccagaag cccgtccgtc aagcagtccc gtccaacacc tgaacacctg
    17701 agagtataac tccttcggcg aaatccattc ttctcctgca tgacatcatt cggtttatta
    17761 aattatgtct atgataccca aaaagcctag tgatgtcaac aagcaattta actgatggct
    17821 aactccttgt ttttatggta acatcattgt cctctttttt ctttttgact gaaacatgat
    17881 ataatcgtaa ggttaataaa agtcacttat tagacgatat gaggagaaag catgaatcct
    17941 ttattagatg gaatgaatga taaacaagca gaggcagttc aaacgactga gggccccttg
    18001 ttaattatgg ctggtgccgg ttctgggaaa acgagggtat taacccaccg cattgcctac
    18061 ttgattgatg aaaagtatgt taatccctgg aatattttgg cgattacctt tactaataag
    18121 gctgcgcgtg agatgcgaga aagggcattg gccttaagcc cagccaccaa ggataccttg
    18181 attgcgacct ttcactcaat gtgtgttcgt attttacgcc gtgaggcaga tcatattggc
    18241 tacaatcgga atttcacgat tgttgatcca ggagaacagc ggaccttaat gaagagaata
    18301 gtaaaagctc taaatctgga tcctaagaaa tggagcgagc ggtcgatttt agccaccatt
    18361 tcaaatgcta aaaatgatct cttagatgaa agagcctatg agctaggagc ctctgatttg
    18421 tatagccaga cagttgcccg ctgctacaag gcctatcagg aggagctcag acgaagtgag
    18481 gctatggatt ttgatgattt gattatgatg accttacgcc tatttgatca aaatcctgac
    18541 gttctagcct attatcagca gcgttatcaa tatatacatg tcgatgaata ccaagacaca
    18601 aaccacgctc aatatcagct agtgactctt ttagcctcac gctttaaaaa tatttgtgtt
    18661 gtcggtgatg cagaccagtc catttatggc tggcgtggtg ctgatatgca aaatatttta
    18721 gattttgaaa aggattaccc tgatgcaagg gtggttttgc tggaagaaaa ttatcgctcc
    18781 accaagaaaa tccttcaggc agctaacgag gtgattcagc ataatcgtca tcgtcgtccg
    18841 aaaaaattgt ggactcaaaa cgcagacggt gagcagattg tttattatag ggcaaatgat
    18901 gagcgtgacg aggctgtttt tgttgcctca accatcagca atatgtgtct agagctagga
    18961 aagagcttta aagactttgc tgttttatat cgtaccaatg ctcagtcccg tacgattgaa
    19021 gaagccttgt taaaatcaaa tattccctac acgatggtcg gaggaaccaa attctacagc
    19081 agaaaggaaa ttcgtgatgt gattgcctat ttgactgtgg ttgctaatcc gtcagataat
    19141 ctctcctttg aacgaattgt gaatgagcct aaacgagggg tagggccagg aaccctagat
    19201 aagctccgcc aatttgctta tgggcaagga cagtcattgt tagaggccgc ttcaagcctt
    19261 gagcaatcac cgctaaaagg aaaggctgcc caagccatgc tggccttagc gagtctctta
    19321 agtgatttga gagctgattt agaccagctg agcattacag ccctggccga ggccttgctg
    19381 gagaaaaccg gctatctgga tatgctgcgc gtccaaaata ccttagaaag tcaagctagg
    19441 attgaaaata ttgaagaatt cctgtctgtt accaaaagct ttgatgacct atcagcacag
    19501 cagcaggagc atgaagcagg tattgatcgc ttaggaagat ttctcaatga ccttgctttg
    19561 attgctgata gtgatgatgg caatgcagaa accgctgagg taactttgat gactctgcat
    19621 gcagctaagg ggctagaatt tcctgttgtt tttctcatag gtatggagga gggagtcttt
    19681 cctttagccc gagcagccga ggatcaagat gagctagaag aagaaaggcg actagcctat
    19741 gttggcatta ccagagccga ggaatgcttg tttttaacga atgccaatac acgtacccta
    19801 tttggtaaaa gcagctataa tcgcccaaca aggtttttaa aagagatgtc agagaacctt
    19861 ttaagcttcc aaggcttggc aagacctgct catgcttcct ttggtgtgac attttcgcag
    19921 cagggtcaac gacaatttgg cacaggaatg agtctatcag aggctatcca gtccagaaaa
    19981 tcaatggcac agcctgccag agcagcctca acatctacac cgctgccctt tggaccgaat
    20041 gcagctactt caaagcaagc cgttgattgg cagattggtg atattgccca tcataaaaaa
    20101 tggggtgctg gaacggtttt agaggtcaag ggatctggta agaccatgga attaaccatt
    20161 agttttcctg atgtcggatt aaaaaaactc cttgccagcg ttgctcctat tgaaaaaaaa
    20221 taaaaggtac agcttatggg caatttgcat agtcacttgg ataagggctt tgcaattgcg
    20281 gtttagttct gcgatttaag aaaagaagta agcaaggatt ttatcagtta accacatacc
    20341 aagcttttga tggccttgat gccggagaga gcttggtatt tttttatttt taaaaaaatc
    20401 acaaaaaatg atttattctg agcataatcc ttgcaaatta aaatgagaag tgtataatgg
    20461 caatataaat taaataacaa gtggtcactt ttgttaatag ttgttttaag gtatttgtag
    20521 cgctttattg ttaaacataa atgtatcaaa aaaataacta gcaattttat atttaattta
    20581 tgtagtcact ttaaagagtg aacaaagtag ttttattgaa ttgaggagat ttattatggg
    20641 aattatttgg acattaattg tgggtgcact tatcggtgct attgccggtg cgcttactaa
    20701 aaaaggcgga tcaatgggct ggattgccaa tatcgctgca ggacttattg gatcatacgt
    20761 tggtcaagct ttgtttggca gctggggtct aacattagct ggcatggcac ttttcccatc
    20821 aatcattggt gctgttatcg ttgttatcat tacttctttt gtactaaata aatcaaacta
    20881 agggcatttc tatcattata gagatggttg agtaggaaag aggtttttat gtcgaaattt
    20941 ttaaaaatta gctatagtct cattggctta gtcctattga cggtctttgg tggcgtgata
    21001 gccataactg gagattatat taggctacct attggctatc aatggcttca ctgggatatg
    21061 aattggcttc ctaaattcct aaatccggcc ttatattact attacttttg ggcagctatc
    21121 gctttatttc taataacagt gctgatcctt cttgtgatta tcttttatcc acgcacctat
    21181 actgagattc agctggctaa ggataaagga accctgcttt tgaaagggtc tgctattgaa
    21241 ggctatgtag cagctgctat taaagcagca gggcttatgt caagcccaag agttaccgct
    21301 aagctgtaca agcgtaaatt taaggttaat gtcagtggac aattagcttc tcgcgtagct
    21361 gtcactgagc agctaaatgg cattaaagaa ggaattgaga ctggtttaac agaattcttt
    21421 ggtattaatc gacctgtcca tttcaaggtt tatgtcaagg atattgctga tgctaagcaa
    21481 aagcatagct ctaagagacg tgtagaatag gagattatca tggcatttta tgaacggttt
    21541 aaatacccta ttattggtgg tctgataggg ctgatagctg ctgtattact gatgaccttt
    21601 gggttattta aaacactgct ggcaattatt ttcattattt taggagtata tggcggcctg
    21661 tatgccaaaa agacaggtat tatcgatcaa ttgatcaaac gtaactaaag gagatttatc
    21721 atgactgaaa cttacattaa aaacacaact cataaagaac caacttcagc tgttcgtggc
    21781 gaattgacct atgatgacaa ggtcattgaa aagatcgttg gcttggctct tgaaaacatt
    21841 gatggcctac taggtgttaa tggtggcttt ttggccaatc taaaagacaa gcttgttaat
    21901 agtgattctg ttcgtgatgg ggttaatgtt gaggttggta aaaaagaggt tgctgttgat
    21961 ttagacattg tagcagaata ccaaaagcat gttccaacca tttttgatgc gattaaatct
    22021 gtcgtagaaa atgaagtcaa gagaatgaca gatttagagg tgattgaggt taatgttaag
    22081 gttgttgaca ttaaaaccaa ggagcaattt gaagctgata aggtcagcct acaggataag
    22141 gtgactgagg tagctcgctc aacctctgaa tttacaagca agcaggtaga caatgttaag
    22201 gcatctgtag gtgcaggtgt agaaaaggtt caagagcaaa ctgagccacg cgttaagtaa
    22261 gctaggctgt caaacgatag aaatagagga aatcataatg tcagaagaaa aggtaaatgc
    22321 aaaattggag caagcaggcg gtaaaatcaa agaagccttt ggaaaggtga ctggtgataa
    22381 atccttagaa accgaaggta aggttgatca agcagccagc aaaatcaaag aagtagctgc
    22441 tgatgctaag gacgctgtca agggctttgt taagggcctt aagcaagata aataaggagt
    22501 tgtaatgaaa gcaaaggaca taaaaagtac gttgacctac gatgataagg tcattgaaaa
    22561 aatcgttgga catgctttag agaaggtcag tggcttatta gcagtcaatg gtggcttttt
    22621 ctcaaatatc aaaaataacc tagtgaatag tgactctgtt cgtgatgggg tgtctgttga
    22681 ggttggcagc aaggaagtgg ctgttgactt agatattgtt gttgaatatg gtaaggatat
    22741 tccagcaatt gttgagtcta tcaaggctat tgtttttcaa aatgtcgata gcatgacaca
    22801 tttgagggtc gttgaagtaa atgtgaacgt tgttgatatt agaaccaaag aagagcatga
    22861 ggctgctagc gtcactgttc aagacaggct aacagacgcg gcctcagcaa cctctcaatt
    22921 tgtagctgag caagcagaca aggtaaaaga aactgtctct aaaaccacag ataataacga
    22981 gacagtagaa taaaacacaa caactaaaac tcctgttaat gacatattgt gggctggtgt
    23041 gatgaccagc tctttttatc agtgcttgaa caatgttatg ctattgtatt ctctgtgaaa
    23101 atgtgattta atgggaatgg tatcatttgt taaaaaggag taattatcat gactagtaat
    23161 aagagagaga ttactaattc caagtatcaa aagattgcca tttcagttgc tgaaaggatt
    23221 gccaatggcg aatatgaagt gggagaaaag ctaaagtcta ggacaaccat tgcttcgacc
    23281 tttaaagttt cgcctgaaac tgctagaaag ggtctgaata ttttagctga tctgaagatt
    23341 ttgaccttaa agcatgggag tggcgccatt gtcttgtcta aggaaaaggc tattgatttt
    23401 ctgaaccaat acgaatccac ccattctatc gctgtcatca aagaaaatat tcgccataat
    23461 attcgtgagc aggaaaaggc aatggagcat ttaacagtgc ttgttaatga gtttctgatg
    23521 caaagccaat caatcagcaa gcaatacccg ctggcacctt acgaaattat ttgtagtcag
    23581 gattcagagc attttggcca atccattggt gatttgaaca tttggcatca aacgggagcg
    23641 acgattgtag ctattgagca tgatggccaa ttcattgttt ctcccggtcc ttacgctgtt
    23701 atcgaaaaag gtgatcatat ttactttgtc ggtaatgagg acgtgatttc tagaatgaaa
    23761 acctttttta atgttagaaa gggtctgtaa tcacaaaaaa acacagagct gctttaaggt
    23821 gatggtgata tcacgatgaa gtgtctctgt gtttttgtgt tatcaggcta aggcttctaa
    23881 gtagcttata gctctgattg aagcccctag attacttttt caaagccaac agttttcagg
    23941 ataatagctg tcatgtcatc ggttgtttct tgacagtcat gactaatcca gtagctaatc
    24001 agactttcaa tactggctag ataaacctca agcgcgtagt gataagggat ctgatagtgc
    24061 ttggtgatga tttcttgaaa gccatcaata gtggtcaaaa attgataaat aaaatccttg
    24121 agtatttgtg aaaaattcaa ataactggag ttagccatag cagcaataaa gggaagatta
    24181 tcaatgatat aagcgagggc ttcctttaga acgagtctag tatctgtaaa aatatgaggg
    24241 tcatttagga gctggtataa atcgtctaag gtgtcattta tgagatgagt catcatatca
    24301 tgtttatccc tgtaatgcag ataaaaggtg cctctattga caccagcttt tttggttaag
    24361 tcagaaacgg taatggtctc aaagctcttt tctgtcaaaa gactgacaag tgcctgcttc
    24421 aaataggcct tggttggtgt gtgtcttgtt gtcatcgact catctcctta agtcaacaaa
    24481 tgctgcttat ctgttcttgt taaagtcttg aggacattat ataataaggc tagtataaaa
    24541 tcaacaaggt gttgatataa aggaggtgac atgatcagtg tcctatattg aaatgaggtc
    24601 ctcttcaaag acctaccaga ttggagaaac aactgttaag gctaatgatg aggtatcctt
    24661 tgagattgaa agaggggagc ttgtgatcat tttaggagcc tctggtgcag gcaagtccac
    24721 agtgcttaat attttaggcg gcatggatag caatgaccaa ggtcaggtca taatagacgg
    24781 caaggacatc tcgacctata gtaaaaaggc attgaccagc taccgtcgtt acgaggttgg
    24841 ctttgttttt caattttaca atctggtgcc aaatctgaca gcaaaggaaa atgttgagct
    24901 ggcggctgat attgtggcag atgcacttga tccgactact gtcttaaatg aggtggggct
    24961 aggaggacgt ttggagcatt tcccagcaca gctatcagga ggtgagcagc aaagggtgtc
    25021 tattgctcgt gccttggcta aaaatcctaa gttgttgctt tgtgatgagc caacaggggc
    25081 tttagattat caaaccggca agcaaatttt aagattgctt caagatatgg cgcacgacaa
    25141 gggcaggaca gttattgtgg tgacgcataa tactgctcta gcgcctattg ctgatcgggt
    25201 catttatatg catgacggtc gtgtgaccaa gacagtgctt aataagcagc cgcttgatat
    25261 tgataggata acgtattgag aggtgcctag atgaaacaaa aaaccttatg gaaggatagt
    25321 tttcgagcaa taaaagctag taaggggcgt tttttgtcct tgctattttt aatggctcta
    25381 ggctcctttg ccttggttgg cttaaaggtg gctggtccca atatggaaaa aactgctagt
    25441 cactatctag aggagcatca ggttatggac cttagtatcc taacctcgca tggcttttct
    25501 gatagagata agcaagaatt agcctctctt aaaaatgcaa gactagagta tgcgagcttt
    25561 gttgatggtg cttttgatca ccagaggaag gctattaggc tttattctat gccacaaagc
    25621 ctatctcagg ccagcttggt caagggagat taccctagca aggctagcga cattttgcta
    25681 tctgaagctt tatcaagccg ctatcggctt gggcaaataa tcacgataag cctaaaaaca
    25741 aagggattgc taaagcatag atcctatcgt gttgtcggct ttgctcattc tccagaaata
    25801 tggtccaaaa caaacttagg tgtttcctca gcaggggatg gtaatctcta tgcctatgcc
    25861 taccttcacc ctagtgcctt tcagcaaggg cacaatctct tacgcattcg gtatgatgat
    25921 ttaagagggt tgaatgcctt ttcaactcaa tacaatgaac gattgctaca acaccaagca
    25981 gagcttgatc agatcttgca ggacaatggt caagagcgtt atgaagaaat gctcaatgac
    26041 cttaatcgca gcttgaaaga tagtaaagtt aagctcgaag agcaaaggac tgttcttaag
    26101 gcaagtgaag accagctggc tttgctaagt ggtcatgcct tagagcaagc gcagactcag
    26161 ctaaagcaag ggcaggaaga gttagctaaa aaagaagcaa gcttgctaga gttagctgaa
    26221 aagcaaaggg cagcgatgat caagccaacc tatactagct atagtcgctc aacgctgcca
    26281 ggtggtgagg gttatcaaac ctatgccacc tcaacacagt ccatatcgca tgttggaaat
    26341 atctttcctg ttgttttgta tttggttgcg gccttagtta cttttacaac aatggctcgc
    26401 tatgttgacg aagaacgaac gaactcaggc ttactaaagg caataggcta ttctgattgg
    26461 gatattacca aaaaatttct gctatatggt gccttagctg ccttgttggg cactggatta
    26521 ggagttttag gagggactta ttttttatct cggctcatct cagctatcct aacagatgca
    26581 ttgactatcg gctctactca gctttatttt tattggagct atagtgtggt tgcagtgctt
    26641 ttagccttgt tatctgctgt tttgacagct tatatggtgg tgagacgtga gctttttctc
    26701 agaccctcac aactgttgct gcctaagcct cctagtagcg gggcaaggat ttggctggag
    26761 catgtctcct ttatctggcg gcgtttatcc tttacctata aggttacttt tcgaaatatc
    26821 tttcgatata agcaaagaat gctgatgaca gtaattggag tagcaggttc tgttgcgctc
    26881 ttattttccg gcttgggcat tcaatcctca cttgctaata gcctaagcta tcaatttggc
    26941 aagctgacag cctatgacat gctcgtggta gaagctccaa cagcagaagc tcatgatagg
    27001 caggagctgg cacaatattt gaaggcagat cagattgcta gtaagaaaga gatttattac
    27061 gctaacttat cactaaagat aaaagactta gacaacaagc aaacagtgtc gttgatttct
    27121 agcgatcaga gcactctatc tccctatttt agcttgattg gtgctgctga ccgaaaaaag
    27181 ctagaccttc caagtactgg agtgcttatc tcaaaaaagc ttgctgacta ttatcaggct
    27241 catgcaggag atcagcttga gcttgaagct agtaacggta aacgctatca gttaagagtg
    27301 agtcaggtta ttgacatgac tgttggtcat tacttgttca tgtctaaatc ttattatcag
    27361 caggtatttc gggatatgga ggcttcacca tcctatttgg taacaacagc aaaggctagt
    27421 ccatctgctg taaaggacgt agctagtcag ctcttagcaa tgcctgcggt tcaggctgtg
    27481 tcacaacaca gtagtattgt tgctactgtg acagggattg tggcgtcttt ggatcaggtt
    27541 atgacgcttt tagtacttct atcagttcta ctagccttgg tcattttgta tcatttgacc
    27601 aatatcaata ttgctgagag ggttagggaa ttatcaacga taagagtctt gggcttttat
    27661 gacaaggagg ttaccttata catttaccgg gaaaccatgc ttttgtctgc tgttggtatt
    27721 ttgatcggtc tctggggtgg cagctatttg cacgcctata tcatgaaggt gattgctaat
    27781 gattctatga gctttggtag gacagttgat gcttatgttt acctagtacc tgttggggct
    27841 attgtgcttt tgttgattgt gcttggctat atggttagct accggctaag aaagattgat
    27901 atgctagagg ctctaaagtc tgttgattag ggtaaaatag tacttgaaaa tcgcttaata
    27961 atatgctagt attaaaatac tataatttaa tagaaggata cttttatgga agcgatgata
    28021 gctgcctatt tggctgatca tagagaaaag ataccacttg gtcaggttgt tgattgcttt
    28081 aaggggaagg ctgtttctcg taaggctgag gctggtgaat ttggtttgat taatctgtct
    28141 gatatgggac agctaggaat tgactatcat caggttagag cctttcatat ggatagacga
    28201 caactattgc gctatatctt agaggatgga gatgtcttga ttgcctcaaa ggggactgtt
    28261 cagaaggttt gtgtttttca taagcaagaa agggaaatgg tagcgtcctc taatatcaca
    28321 gtgctgcgtc ctcagagggt tttgcgaggc tattatatta agttcttttt ggagtctgct
    28381 attggtcaag ccttgttaaa ggcggcggat catggaaagg acgtgattaa cctatcgacc
    28441 aaggctttac ttgatatccc tgtaccagtg attcctttgg ttaagcagga ttatttgatt
    28501 aatcaatatt tgcgaggcct gcatgactat caacggaaag taaacagagc tgagcaggag
    28561 tggcagttta ttcaaaatga aattcaaaaa ggcttgggct agaggtaaaa tgtgagctta
    28621 attgaacgaa caataaaaat gctattagca acgatggctg caatctttct tgcctctcag
    28681 ctacagctgt cttatgccat atcagcggga attattgccc tgttaggtgt gctagacact
    28741 agaaaatcta gcttaattgt tgctagaaag cgtctgctgt cttttttctt agcctttgct
    28801 gtggcggtta gtctatttgc cttatttggc tttggtctgc tttccattgg cttgtatcta
    28861 gcgctaacca ttcctttgct ttatcagctg aaaatagagg caggtcttgt tcctatcact
    28921 gtcttggtga ctcacctgat gtctgagcag cgtattgatt tgtcaattct ttttaatgag
    28981 ctgttgctgt ttttgattgg gacgggtctt gcccttcttg ttaacgggta tatggggtct
    29041 caggagcatc gcctacgctt gtaccaccaa aagatagaag atagcttaaa ggctatcttg
    29101 taccgttttg aatccttttt gttagaaggc caaggacaaa acgagggaca gatgattaag
    29161 gaattagagc ttagcttaga tgaggcgcta aagctggttt atcgcgaaag gcacaatacc
    29221 ctcttttatc ataccaatta tcaggtgcat tattttgaga tgagacgtca tcaaaataga
    29281 ttgttggcgc aaatggcctt aaatgtcact cagctaacat ctcaaagcag agaaagtctc
    29341 ctgctctccc atctttttca tgagacagct cgtcagctga gtgagaagaa ttctgctttg
    29401 acattgattg atgatattga gcaattgctt gaggtcttta ggcaaagaga gctgcctcag
    29461 actagagagg aatttgaaag acgggcgatt ctgtttcagc tgttgcagga tttggagcgc
    29521 tttattctac tgaaggtaga attttatcgt gattacaagg aagagcaggc atagtagctg
    29581 cttgctgctg tgattaagag tctggaaaaa tcattttcta ggcttttttg ctata
//
LOCUS       DARYLJ010000030        29367 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYLJ010000030 DARYLJ010000000
VERSION     DARYLJ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29367
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            45..359
                     /locus_tag="TU746_001197"
     CDS             45..359
                     /locus_tag="TU746_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0891546.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            364..696
                     /locus_tag="TU746_001198"
     CDS             364..696
                     /locus_tag="TU746_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL0891547.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            698..2296
                     /locus_tag="TU746_001199"
     CDS             698..2296
                     /locus_tag="TU746_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891548.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            2290..2976
                     /locus_tag="TU746_001200"
     CDS             2290..2976
                     /locus_tag="TU746_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891549.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            2998..3684
                     /locus_tag="TU746_001201"
     CDS             2998..3684
                     /locus_tag="TU746_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891550.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            3706..4383
                     /locus_tag="TU746_001202"
     CDS             3706..4383
                     /locus_tag="TU746_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891551.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            4390..4704
                     /locus_tag="TU746_001203"
     CDS             4390..4704
                     /locus_tag="TU746_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0891552.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            5152..5835
                     /gene="rpiA"
                     /locus_tag="TU746_001204"
     CDS             5152..5835
                     /gene="rpiA"
                     /locus_tag="TU746_001204"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL0891553.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            5913..7124
                     /locus_tag="TU746_001205"
     CDS             5913..7124
                     /locus_tag="TU746_001205"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL0891554.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            7337..8146
                     /locus_tag="TU746_001206"
     CDS             7337..8146
                     /locus_tag="TU746_001206"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL0891555.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            8237..9022
                     /locus_tag="TU746_001207"
     CDS             8237..9022
                     /locus_tag="TU746_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL0891556.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(9155..10063)
                     /locus_tag="TU746_001208"
     CDS             complement(9155..10063)
                     /locus_tag="TU746_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0891557.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            10403..10852
                     /locus_tag="TU746_001209"
     CDS             10403..10852
                     /locus_tag="TU746_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891558.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            11473..12165
                     /gene="pyrF"
                     /locus_tag="TU746_001210"
     CDS             11473..12165
                     /gene="pyrF"
                     /locus_tag="TU746_001210"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL0891559.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            12225..12860
                     /locus_tag="TU746_001211"
     CDS             12225..12860
                     /locus_tag="TU746_001211"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL0891560.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            12912..13655
                     /locus_tag="TU746_001212"
     CDS             12912..13655
                     /locus_tag="TU746_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0891561.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            13890..15344
                     /locus_tag="TU746_001213"
     CDS             13890..15344
                     /locus_tag="TU746_001213"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL0891562.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            15464..16330
                     /locus_tag="TU746_001214"
     CDS             15464..16330
                     /locus_tag="TU746_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0891563.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            16358..17011
                     /locus_tag="TU746_001215"
     CDS             16358..17011
                     /locus_tag="TU746_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0891564.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            17142..17549
                     /locus_tag="TU746_001216"
     CDS             17142..17549
                     /locus_tag="TU746_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0891565.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            17561..18214
                     /locus_tag="TU746_001217"
     CDS             17561..18214
                     /locus_tag="TU746_001217"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL0891566.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            18446..19720
                     /locus_tag="TU746_001218"
     CDS             18446..19720
                     /locus_tag="TU746_001218"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL0891567.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(19774..20421)
                     /gene="plsY"
                     /locus_tag="TU746_001219"
     CDS             complement(19774..20421)
                     /gene="plsY"
                     /locus_tag="TU746_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL0891568.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            20554..22503
                     /gene="parE"
                     /locus_tag="TU746_001220"
     CDS             20554..22503
                     /gene="parE"
                     /locus_tag="TU746_001220"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL0891569.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            22605..23420
                     /locus_tag="TU746_001221"
     CDS             22605..23420
                     /locus_tag="TU746_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL0891570.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            23895..26354
                     /gene="parC"
                     /locus_tag="TU746_001222"
     CDS             23895..26354
                     /gene="parC"
                     /locus_tag="TU746_001222"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL0891571.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            26452..27477
                     /locus_tag="TU746_001223"
     CDS             26452..27477
                     /locus_tag="TU746_001223"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL0891572.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            27545..27775
                     /locus_tag="TU746_001224"
     CDS             27545..27775
                     /locus_tag="TU746_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL0891573.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            27836..27916
                     /locus_tag="TU746_001225"
     tRNA            27836..27916
                     /locus_tag="TU746_001225"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27870..27872,aa:Tyr,seq:gta)
     gene            27955..28026
                     /locus_tag="TU746_001226"
     tRNA            27955..28026
                     /locus_tag="TU746_001226"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27987..27989,aa:Gln,seq:ttg)
     gene            28154..29356
                     /gene="rpsA"
                     /locus_tag="TU746_001227"
     CDS             28154..29356
                     /gene="rpsA"
                     /locus_tag="TU746_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL0891574.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         8506 a         5462 c         6976 g         8423 t
ORIGIN      
        1 tataataaaa tatatacaat tattagagag ttagaaagag ttatatggta gtattacaaa
       61 ataatagtag cacagctagt gagcgagcga cagctttggc aagaggagtc caggccctct
      121 ctagtgctgg tgcggtgagc aaagatatga agacgaccgt tactggaaat cgtagtgatg
      181 ccagctctgc cattgattta tcgcacaacg tttcagcgca ggtagttggg atcatcgctt
      241 ctatgtcgca acacattcag agtgtctctg cctcttttca agcgatggat cttcagcttg
      301 gaaaagagtt agggcgttta gaaaacaggc ggaggtttag tctcaatgac ccaaaatgag
      361 ctcatgtacc agaaggagag attggataaa cgcttggaaa ccatagccca agagcttaag
      421 cgtaatgaac agcgctttga agactatgag gaactatcta acctagcggc acaactgtta
      481 acagcagctg caaccacctt tcgttcatca tcagatagtc atctctttga aggggctttg
      541 gcagaagaat gttatttgaa aaggaaaaca caagcgtcct tggaacaaag tcatgaggag
      601 ctcttaggag agcagcgtcg tttgtaccaa gaagaggaag cccttacccg acaattaaag
      661 ctagtcaaag gaaaggagag agctaatgag cattgacatg tatctggggt catcggacca
      721 gcaagctagt agcgttggta aggtcttgca gcagcggata acagcttata agtctttgca
      781 aagagctttg gagcaattgg tgtcttctag tcctgactta tcagggcata cctatgcttc
      841 tgctaaaagg tacagcgagc aggtattgat ccctttgatg aggggctgta tcctgctaga
      901 tgaagccatc aaggaagcct gtgcagcatt tcctaatgac taccgtcgtc aggttgatag
      961 tgtggatttg aaggagagtg agctggtgga tcagatcagc cgctcagacc gcatcatagg
     1021 tcgttacgtt gagttgattg atctggagta tcggcaggag ctgccgaatt actcttatat
     1081 tactaatctc aagagcggag cgagtaacca gcgtcaagtc aagagaaaat tagaagagaa
     1141 gctccttaag ctgcgagagt ttgatagcaa ttcccgtcac ctcttttcgt ctatcgcagc
     1201 cttagccgag gcagtcaata taggtatcag acaaaccaag acctcttgga atgggacaag
     1261 tcagacgttc actcttccca gggctcttga cttagagtgg accaaggtag tagaaaagag
     1321 gtggacgcaa agggaggaaa aagcctcgaa gctgaagcta cagcaggcag cagaaaaact
     1381 ttcgagagaa accgggatta agtacgaaga tgcctatcgt tttgtgatgg acggtgttct
     1441 gtcagatgaa aataagaaca aaatcaagag tgtaaagaaa ctagttaagt atacaaaggg
     1501 tgggctgtat atcgtttcct caggaaggta ttattggaaa cattcaggta aacattattg
     1561 gaaaaataca ccaaacaaaa catggaatat ttggaaagca tctaaaaacg atcccaattt
     1621 tgacaaagga gggatcaaag gtaaacattt ttctaaaaaa ggagcccgtt acacagactt
     1681 acctggtatc aagcaattga agaagagtga aacagtacaa tccctcattt caaaaatttc
     1741 aaaagataat caagggaagc tcaccaaagt tggtaaaggg ttaaagaaag ttgataaaga
     1801 gctaagcaac atatcgtcaa aactcaagtc atatgagcat ggacgcctaa atagagactt
     1861 gaaaatgatg aaggagaata acctgggtaa aagtctcggt aagtttggga aagttggaaa
     1921 agctgcaagc aaggtgctca agtttgcagg aaaaggtctc aaagttgcgg gttgggtagg
     1981 tgctgctata aatgttaagg actcggttga aacttacaag aaaaaaggct atagcaatga
     2041 gcaaactgct gctttaacag cccgtaaggt agctgttgat actgcaacaa ctgttgtcgg
     2101 aagcaatatt gggcgtgtaa caggtgcagt tattggtcaa gcagttatac ctattccagg
     2161 tgtaggtgct gctatcggtt ctgttgcagg aagtatttta ggagctatgg caggtagttg
     2221 gattggtagt acaattaatg acaatttaga taagaacgta aaacctaaac aatcaggaag
     2281 gagtttagca tggtaatgtt aatgagaaca ctgttatttc cagttgataa cggacttgat
     2341 tcaggattga ctggtgatgg ttatgcagct gagtatgatt tgtggactgg aaaggtcacg
     2401 tggcgacaac ttggtgatgg aaaaataaaa aggcaacaaa aggtagcagc tataattaat
     2461 ctcattgcag ctgcaatatc tccacttgtc atcatgtcta tcatttttac ggcaaaaagt
     2521 ctgaagcttt ttgatgtaga tactagtaca acaatttatc gatatgctcc tctgatggta
     2581 ggcttggtct ttttcttctc gtttgaatta ttgatgctgg ctattagacg tctgtatcca
     2641 ttagccaaag aggagccaag tttaaagcgt caacatgggt attttaagac catgtatgac
     2701 aatactatac gtgagaatga tggtgttttt aataatttat cagtaccttt tatagggctt
     2761 tatgtagctt tcttgattgc cttttcggtt attccaattt tttactctca atatctgcag
     2821 caaaattctt tttggtccta tttaggaaat ttagtaggaa gtagcattct tatttcctta
     2881 gtccccaatt ttttatggaa tgtcttagtg aaacaattga tttacatcaa gcttattcgc
     2941 aaaacgaaag aaaaaatctt aaagaatgaa acctaaacaa tcaggaagga gtttagcatg
     3001 gtaatgttaa tgagaacctt gttatttccc atagataatg gtatggataa taacttaatt
     3061 ggagacggct tatcagctga gtatgaccta tggactggaa aagttacgtg gcgtcagccc
     3121 agtgatgata agattagaac ccaacaaaag gtagcatttg tacttaatct tatagctggt
     3181 agtttatctc cattagctat atttttattt gttattattg ttagacgctt aggcgttttt
     3241 agtggcgata ctaattcaat gattttcaag tgggcaccgc taatagttgg atttatcctt
     3301 tttatatcgt ttgaattatt gatgttggcg cttagaagta gatatacgat attagagaaa
     3361 gagcccgatt tagatcgtca actatactat tatcgtacaa tgtatgataa tactatacat
     3421 gacaattcag gtgtttttaa caatttatca gtaccttatg taggtctata cattacttta
     3481 tttctaattt ttttaatcat tccactttgt tatcattttt acttgcaccc atcttcattt
     3541 ggggattatc tcgctgcatt atctgtaaca agtttgttga tttccttatt tcccaatttt
     3601 ttatggaatg gtgtcttgaa gcacgttata tatgtcaaac ttattcgcca aacaaaagaa
     3661 agaattttaa agaatgaaac ctaaacaatc aggaaggagc ttagcatggt aatgttaatg
     3721 agaacgctgt tattcccagt tgataatggc atgggaacgg gcttgaccgg tgatggttat
     3781 gcggctgagt atgatctatg gactggaaag gtcacgtggc gacaagccac caaacaaaca
     3841 attgaaaagc aacaagcact aacgtctaac cttttgatta ttgcctcatg cttatcacca
     3901 gttactgttg caggaatgat actgttgagt agaagtttcc ctattttcga ggaagactta
     3961 tcagagaaaa ttgatactta tgctccaatt attcttggtg ttgtgttatt tcttgctttt
     4021 gagacgttaa tgcttgctat cagaggtcgt gatccattag cggagaagga accagattta
     4081 aagcggcagc atgactattt tgaaaagatg tttgattttg ctattcgtag aaatttgtcg
     4141 tcagataatc taaaaactcc ttatatagct acttattttg cttttggtat ttctttactc
     4201 tgtattccat ttagctatta tgtttatctg aatccggagc aattccctaa tttggattat
     4261 ggtcatttat caatcctgct tgtaacaagt attcttattt ccctagttcc caacttttta
     4321 tggaatgttc tattaaagca cattatctat atcaagctta ttcgcaaaac gaaaggacaa
     4381 taaaacatta tgaacaaacc agaacacatt ttaccgattg gtactatagt gctgacggag
     4441 acaggagaaa ttcctttgat gattgtgagt cgtgcctctc tttttgatga taatggagaa
     4501 atcggctatt ttgattatgc tgcagttcct tatccagaag gcataggaaa tgataatgag
     4561 taccttttct tcaaccatga ggatattgct gatgtcatct attttgggta tgtcaattcc
     4621 aatgaacagc tttttgcaga agcctacgat gatttggtga aaacatcagg ttatcgtaaa
     4681 ttaagcttag atcaccatca atagaaaaag gacatgaaga ttatctagaa aaagaaaaga
     4741 actaatgagc attgacatgt atctggggtc atcgaaccag caggctaatg atgtatggcc
     4801 aatattttga gaggatcggc ctgctcctct tttttgtatg ttcaaagcta taaaaagctt
     4861 actttttgag gtataaagct tcgacaatca agagtatttg ctctggtggc tttaatgatc
     4921 ttgcttatag cttctggtca gattgtttta gcctgcttgt gctgtctgat ccagatttga
     4981 ctgaggcttt gatgacagtc gtgaaggcgg gtttaagaat ggcatgtcta atgtcaattt
     5041 acaatagaga aggaaaattg atcaaacagt gtgagatatt attaacaagt ttgcgctttc
     5101 atggtataat aaagtgctag gaagcatttt attataagat aagggggaat catggaagca
     5161 ctgaaaaaga ttgccggtgt gactgctgcg caatatgtaa cagatggaat gaccattgga
     5221 ttaggaacag gatcaacagc ttattacttt gttgaagaaa ttggtcgtcg catcaaggaa
     5281 gagggactac aggttgttgg tgtgacaacc tcaagtgtaa caaccaagca agcagagggc
     5341 ctaggtattc ccttaacatc aattgatgat attgactgca ttgacctgac tgttgatggt
     5401 gctgatgagg tggataaggc ctttaacggt attaagggtg gtggagcagc tctattgatg
     5461 gagaaaattg ttgcaacacc aaccaaggaa tacatctggg ttgttgatga atcaaagctg
     5521 gtggatcatt taggtgcttt caagctccct gttgaggtcg ttcaatacgg tgctgatagg
     5581 ctatttcgag tctttgaaag ggctggctat aagccctctt ttcgcatgaa gggggataag
     5641 cgtctcataa cggatatgca gaactttatc attgatctta accttggctg tatcgaaaat
     5701 ccttgtgagt ttgggcgtct gctggatcaa actgttggtg ttgtcgagca tggccttttc
     5761 aatggtatgg ttgataaggt cattgttgct ggtcaggctg gtgtaacggt ccttgaagct
     5821 aatcagtcaa cctaattcct agctcaatca tgttttacat tattttatag gttttgggga
     5881 gccaaccgta acctccccta gattggagac ttatgtcaaa atttaatcgt attcacttag
     5941 tcgttctaga ttctgttggt attggtgcag caccagatgc cgacaaattc tttaatgctg
     6001 gtgtagctga tacagattct gacaccctcg gtcatatttc agagacagct ggtctggctg
     6061 ttccaaatat ggcaaaaatt ggacttggtc atattcctcg tcctgtcccc ctaaagacag
     6121 ttccagctga ggctgatcct actggctatg tcaccaaatt agaagaggta tctcttggta
     6181 aggataccat gacaggtcac tgggaaatta tgggcttaaa cattactgag ccatttgata
     6241 ccttctggga tggctttcca gaggagatta tccaaaaaat cgaagctttt tcaggccgta
     6301 aggtcattcg tgaagccaat aagccttact cagggacaaa ggtgattgat gattttggtc
     6361 cccgtcaaat ggaaactggt gagctgattg tttatacctc tgccgaccct gtattgcaaa
     6421 ttgcagcaca tgaggaggtg attcctgttg aggagcttta ccggatttgt gagtatgcgc
     6481 gttccattac ccttgagcgt cctgctcttt taggtcgtat tattgcccgt ccgtatatag
     6541 gagagccagg cagcttcact cgcacagcta atcgtcgtga ttatgcagtc tcaccgttcc
     6601 aagacactgt cttaaataag ctggctgacg ctgggatttc tacttatgct gttgggaaaa
     6661 tcaatgacat ctttaatggc tcagggatta ccaacgatat ggggcacaat aagtctaaca
     6721 gtcatgggat tgataccctg atcaaaacct tgcagttgcc agcatttaca aaaggtcttt
     6781 cttttactaa cttggttgat tttgatgcta gctttggtca ccgtcgtgat ccagagggct
     6841 atcgtgactg tttgcatgaa tttgatcgtc gcctgccaga gatcattgcc aacatgaagg
     6901 acgatgatct gctcttgatt acagctgatc atggcaatga cccaacctat gctggaactg
     6961 accacacacg tgagtatatt ccattgcttg cttactcagc ctcctgcact ggagcaggtg
     7021 tgattccaca gggacatttt gctgatattt cagcgactat tgccgaaaac ttcggtgtgg
     7081 acactgctat gattggaaca tcattcttag ctgacttggt ataggagtaa gcaaatatca
     7141 tttgataggc caaggagctt ggcgtatcaa attgaaaacc agcgctgtgg ttaggtctat
     7201 taataggctt gtggcaggtt gtctagttct gatgatcggt gtgatattag ttgatttatt
     7261 ggactttgct acagcaaaaa gctcaagaga agtatgcttt atagtaaaaa ataaataaga
     7321 taaagggaga aataagatga cattacttga aaaaattcgt gaaacacagg ctttcctaga
     7381 aagcaagggc attgataagc ctgaatttgg tctcatttta ggctctggtc taggtgagct
     7441 tgccaatgag gttgagcagg cgattgtgat tgattatgct gatattccaa actggggcaa
     7501 atcaacagtt gttggtcatg ctggaaaatt agtttatggt gagctggctg gtcgtaaagt
     7561 attggcactt caagggcgct ttcatttcta tgaaggtaat ccaatggagg ttgtgacctt
     7621 cccggtacgt gtgatgaagg ctctgggctg ccatagcttg ctggtgacaa atgcagcagg
     7681 cggtatcggc tatggtcctg ggacgcttat gctaatcaat gaccatatta atatgacagg
     7741 aacaaacccg ctcattggtg aaaacctaga tgaatttggc ccacgcttcc cagatatgtc
     7801 tgatgcctat acagcagctt atcgtgagac agctcgctca gtagcagaaa aactaggctt
     7861 agacctgcaa gagggtgttt accttggctg ttcaggacca acctatgaaa caccagctga
     7921 gattcgtgcc tttaaggtta tgggagcaga tgctgttggt atgtcaactg ttccagaggt
     7981 tattatcgct gcccactcag gcttgaaggt gcttggaatt tcagcgatta caaactttgc
     8041 agcgggcttc caatcagagc ttaaccatga agaggttgta gaggtaactg agcgtatcaa
     8101 ggaaaacttt aaaggcttgg ttaaggctat tttggcagag ctttaaggct tgctcttaga
     8161 ctagcagtaa ccatgagcga ctgctagtac tttgatcgat aagacgagga aaaataagga
     8221 ttgggacatt agagtgatga ctgatatgga acatacgata agtattcttt tagaagttta
     8281 tgcttatagt catgcctaca aaattgcaag aactctgcct gatttttccc ccaaggtact
     8341 ttatttgctt gagcttttaa aggaaagaag agagcttaac gttgcttatg cctttcaaca
     8401 tagggcggaa aataggctta ttgaggatag acatcaggtt aagcttttgt taaatgaagc
     8461 tcaagaggag gagcagactg caaattacct gcttgatttg gcagctaagg tcaaaaacgg
     8521 tgagattatt gattttgtaa ggtcagtatc gcctgtcttg tatcgtctct ttttgcggct
     8581 gcttgagcag gctgtcccag atgttcaaag ctatattatt gataccaaga atgatcaata
     8641 tgacacttgg aattttaagg cgatggaaaa agccgataat gacctcttta ggagctatct
     8701 ggcacaaaga cagccacgtc atgtgacgac acgcagcttg gctgatttac ttgttttatc
     8761 agagcttcca gctgatatta aaagactagt ggtagtctta aggcagtttg aaaaatcagt
     8821 ccgcaatccc ctagcacatt tgatcaaacc ctttgatgag gaggagctat atcggacaac
     8881 tcatttttcc tctcaagcct ttctagatgg tttgattcgc ttagcagttt tttctggtgt
     8941 taactatatc aaagagccct tctattttga tgtcgttaat gctgtcattg aaaaggagct
     9001 gttagacagc gccaagcctt agctatttga aagattagca ataataaaaa acctgaacga
     9061 tctgaacgag gcttctctaa gctagctatg actagtcagc ttagagcctt agaacaggtc
     9121 tttcaggttt tttatgttta gctagtgtgg ttaattaatg attgaagcta atttcttcta
     9181 gcaggtagtc aataaatcgc tctcccattt ttgagaggtt agccttttcg tgcttgataa
     9241 agacaatctc aatcacatca gggacatcta agggaatagc gacaatctgg tctccattta
     9301 gatttgtgtt taaaataccg ctggcaacgg tgtagccatt taagccaatc atgagattaa
     9361 atagagtagc tcggtcactc accacaatag acttactgtg agggatatgt gccatcatct
     9421 cctctgagaa ataaaaggaa ttgtgaatcc cctgatcata gcttagataa ggaaaatcaa
     9481 ggagatcatc aatggttaag ctggttttat ttgccagagg attggacttg ctgataaaga
     9541 tatgcggtgt ggttttaaat agggtggaaa cggtcaaatg attttcctca aacagcttgg
     9601 taaggacgtc tcggttgtag tcattgataa acaaaacgcc gatttctgag cgaaaatttt
     9661 tcacatcgtc aatgatttcc caggttcttg tttctcgcaa gaaaagctcg tactgggtca
     9721 tatcagcccg ctttaataaa gagacaaaag cattgacaac aaaggcgtaa tgctgagagg
     9781 aaacactaaa gagctcacga ctagtattgt gatttttata gcgatcctct agcagtgctg
     9841 tttgttcaat aatttgtctg gcataagata gaaactcaac cccgtccttg gttaaggtaa
     9901 tgcccttggg attacgaatg aaaatagtaa tgcccatctc ctgctctaat tccttgacag
     9961 cattagacag actgggctgc gtgataaata attgcttagc ggcttcgttc atggaaccgc
    10021 attcaacaat ctttataatg tattgtagtt gttggattct catactgaca gtctatctta
    10081 aatagtacaa agaatcaagt gcctttatta gagcttaaga caaggtttca caagcggtag
    10141 cctagcttgt gcggtgaagc tagcttgatg ctagtgttgt acccaggtaa aaaagagctg
    10201 gcaaataggc agttttatcg ctttttaccg cttatttttg gcatgcctgt gttttgataa
    10261 acggctggtc ttgatcggta aaaagtaatc gtgataatat cagataatac ctatttttcc
    10321 attgctcttt taattttctt gtgttatatt aataatattg atatatttaa tgttttgaga
    10381 taaagggtgg tgatggtgta atatgactgg acaaagtagt catcaggtat taattcaaaa
    10441 gctgttggtc agcactcact atttgacatt atttagagat gagctgaagc tagttgagag
    10501 gacaccatct attttgggaa gtgagtttcc tgtctctctt gttcaaacgg aattaggtga
    10561 tattatcacc ttggtggata ccttaaataa gcagcagcgc ttgattgagt cgaccttttg
    10621 gtatgaggag tcagccttta agctcatgaa caaggcctta gatattgttg ataattggat
    10681 aaaggggata gatggcttaa ttaagctctg ccagtccaag gaggtctttc aggccattgt
    10741 tggtgataaa agaacacgtg tttttggtgt tttgattgat gttttttctt ccctaaaaat
    10801 tagcaccatg tcattgaagg aatttgcagc tccggctgct ctttgccatt agattaagct
    10861 gggctaagct tggatagtgg ctggttaagc ctgcaagttg cccctctcat gacaagtcta
    10921 ggctttattt agggtgagca gtgtgccaag ggtgtattaa gtgctggttg ctttgaagct
    10981 tcgccttgct aggttagctg tgagtgatgt cacgataact gcgcgaaaca gttatttctg
    11041 aattataata caggttaaag taggtacttt taatgttttt cctattgtaa aatctataca
    11101 aaataggata tatttttgaa atagctgaac attaacgtac agcaagcttt attttcttgc
    11161 taaaaatctt ttttatacct ttgtcgtgtg agtaatgtca aaaccctttg acaagggctg
    11221 tcaaaaaagc tataatgatt gagataagtt acctttaagt gagtccagag aggcgagcaa
    11281 ggtacacagg ataagatgag agggtttgct ctcttgattt tcgtgtagcc tcgcttcttt
    11341 ggaagtgagg cttttatggt gtgactttca gttggtctcg tggtaatgat tcataagacc
    11401 aataaaccgc tcgttagacg ggtgggcatg atttgtttgg gagtacccca agctgcatag
    11461 aaaggatagg ttatgcgaga agaacgccct attattgcct tagattttcc ttcctttgag
    11521 gaggtcaagt catttctgtc gctgtttcca gctgatgaga ggctatacgt taagattggt
    11581 atggaactgt attatgctga aggaccagat attgtccgtt atgtcaagtc cttaggtcac
    11641 agtgtttttc tggatttgaa gctgcatgat attccaaata cagtcaaatc aacgatggca
    11701 gtcctatcaa ggcttggtat agacatgacg actgtgcagg ctgctggagg tgtagagatg
    11761 cttagagcag cgcgtgaggg cttggggcag ggtccgattc tcattgcggt gacacagcta
    11821 acatcaacta gcgaagagca aatgcgtgag gatcaaaaca ttcaatccac gctgttagca
    11881 tctgtgcttc actatgccaa gcgtaccgct caggctaagc tagatggcgt ggtttgctca
    11941 gcccatgagg tcaaggccat taagtcagaa gtaccagcag gctttgtgtg tttgacacct
    12001 gggattcgcc cgacaggtgc tgacatcgga gatcaaaagc gggtgatgac acctcatcaa
    12061 gctagagcta tcggaagtga ctatattgtt cttggtcgtc cgatcactca ggctacagac
    12121 cctgtcaagg cttatcacca gattaaggca gagtggaacc gttagcagca ggatcatcat
    12181 gacacatata gctggactat gacaccaagg aaaagaggag aaaaatgaca ctagcagcac
    12241 aaattgcaac agatttactt gagattaagg ccgtttacct aagaccaaag gagcccttta
    12301 cttgggcgtc aggcattaca tcaccgattt atacggacaa tcggatcacc ctttcttatc
    12361 caaaaaccag aagcttgatt gaaaatggct ttgtggagac gattaaggca gtatttccag
    12421 aggttgaggt gattgctggc acagcaactg ctggtattcc acatggtgct atcgttgcag
    12481 ataagatgga cctgcctttt gcctatatcc gcagcaagcc aaaggatcat ggagcaggca
    12541 accaaataga agggcatgtg cgctgcgggc aaaaaatggt gattatcgag gatttgattt
    12601 caacaggtgg atcagttctg gaggcggcag cggcagctag tcgcgaaggt gctgatgtac
    12661 taggagtggt ggcaattttt acctatgaat tgccagtagc aagcatcaat tttgaaaagg
    12721 cagggctttc cttggtgacc ttgtctaatt attcagacct cattaaggtc gctaaggcca
    12781 agggctatat tgatgctgat ggcttggccc tgttaaaaag atttaaggag gatcaaaagc
    12841 attggcagca tgagagttaa acagtgctga aaagctgctg acatgctgac tatgtcttaa
    12901 ggagagaaaa aatgacttac aaagatttac ttgagatagg tgagaccagt tattatcaga
    12961 cggatcgctt gacttactac aaaaatcctg tggtatctga gcgctatttt gataattacc
    13021 ttagctatcg tagcatgcct tctttggctg atttgaaaaa ggacttggcc tatgtggcaa
    13081 aagagcagca ggattatcct agtcactacg cctttctctt ttttgctgaa aatgaagagc
    13141 taagtacaga catgcgagct tatttgacag atcatcactt tagccttgaa aagcacctga
    13201 tctttaccaa tgagctggca aagcttcacc taaaggagcg tgatatatca ccagtcacta
    13261 ttgaacagct ctcagaaaca agcttttctg cctatctggc ttacaaatat caggctaatt
    13321 tggcttatgg tgaaacctat gccaatcaat gcaaggctga taatgaagcc aatctattga
    13381 caaacggctc aaccatttat ttagccatca aggaagggaa gattatcgga gatattacgg
    13441 cttgggaatg tggcgactat attgaaatgg acgatttcag tgtagatgag gcctatcgtg
    13501 gtcgtggtat cggtacagcc ttacagcgta aggccagtca aggctataag aaggtcattc
    13561 tcatctcaga agaagctaat cgcgccatgt atgagcacca aggctatcag gaggttgctt
    13621 actactggac agcgctaaaa acatcgacta gataagtgat aaagaaacag attataggat
    13681 tgaaggtgta ggctcttatg agtatgactc ttcaatcctt tttttctgag cgcatttgct
    13741 aatcatacct aatgaataag tcgtagcctg tctagtggct cattttaatg gcgtcttgct
    13801 ctgttttatg attaaatata gagaaaaagc tattgttagg gcatgcttgt tggtctagca
    13861 aggctgatgg atgataggat agggaattga tgatttttaa agatgcaaca gaaatggcgc
    13921 aggctgttcg agaaggtagg gtgagcccct cagccttagt gagagacaca attaaaaagg
    13981 ctcaagcact caatcctgag ttgaatgcta ttacctcaga gcgtttttca gaagctcttg
    14041 ctgaggcagc agcaagggat ttttctggaa agccatttgc tggtgtgcct atttttctaa
    14101 aggatttagg gcaggagcag gagggccaat tggccactgc aggatcagtg ttatttaagg
    14161 attatcgtgc ctcaaaaacg gattatgttg tgcagcgact agaggagctg ggctttatta
    14221 ttttaggaag aagcaataca cctgaatttg gctttaaaaa tattagtgat agtcgcttac
    14281 atggtccggt aaatctgcca caggacaaga gccgtaatgc tggtggttca tcaggtgggg
    14341 cagcagctct tgtgtcctca ggaatcacct tgctggctcc tgctagtgac ggaggaggat
    14401 ccattcggat tcctgcctcc tttaatggct tgatcggttt aaagccaagc agaggaagag
    14461 tgcctgtggg gccaggctct tatcgtggct ggcagggggc gtctgttcat tttgctctaa
    14521 cgaggtctat tcgagacaca agtcgtcttc tttatcactt gcaggtttat caggtagaaa
    14581 gcccttttcc attagtgcca ttaaccaaag aagagctttt tcacccttta gacagaccct
    14641 taaggattgc tctttatgat cacatgatag atggaactac cgcctctata gatgctcaga
    14701 cagctttaac cgaggcctgt cattttctaa aagagatggg gcatgaggtt gtgcgattag
    14761 ataagcttcc tctagatata ccaaaggtta tgagggatta ctacctgatg actagtgttg
    14821 agacagctgc tatgtttgct gatagccaag aagcccttgg tcgtcaggtg accaaagcag
    14881 atatggaggt catgacctgg gctatctacc aagcgggtaa ggatattctt gcttcggtct
    14941 attctcaggc gctgcagcgc tgggaccatt atagtgctga aatggcaagc tttcatgagc
    15001 agtatgatct tttgctgacc tttaccgcca atacgcctgc tccaaagcat ggacagttcc
    15061 agccaagcaa ggagctaata gataagctgg ctaaggcgga atgctacccc tccagtcagc
    15121 gcctagcgct agtagaagcc atgtttgagc agagcttgtt cataacccct tacacagctt
    15181 tggcaaatct gacaggccaa ccagctctta gtttaccaac ctatgaaacg tctgctggat
    15241 tgccgatggg cattcaattg atagctgcta aagggcgaga agacttattg ctgggaatag
    15301 ctagacagtt tgaacgggct ggattgttaa agctacctgg ttaaatatta taaaacagag
    15361 ctaatctatt ataggttagc ttttttgtta aatcgagcat atctagtctc ttataagatt
    15421 agtcaatgct atactgtcat taataatgaa aaaggagttc ttgatgaaaa aaggagttgc
    15481 tttactttct gttagcttgg cgagcttgct gttagccgcc tgtgggtcac agccatcagc
    15541 tcaaaaaaca agctgggaaa agattaaaga taaaggtgtt ttaaaggttg ctacgcctgc
    15601 gacctaccag ccaacatcgt actataatga tgccaatgaa ttggtcggct atgaggttga
    15661 cctgatgaag gaaattggga aacgccttga tcttaaggtg aagttcattg aaacaggcta
    15721 tgatcaggct tttacttcgg ttgatagcgg tcgtgttgat gtttctctca ataattttga
    15781 cattacagcc aagcggcaaa aaaaatacaa catctcaacg ccttataagt atggtgttgg
    15841 gggaatgatt gttcgtgctg atggcagctc aggcataagc aaggctgacc taagcgattg
    15901 gaaagggaaa aaagcagctg gcgcctctgg tacagaatac atgaaggttg ccaagaagca
    15961 aggtgctgaa ttagtcactt atgataatgt gacgggtgat gtttacctga acgatgttgc
    16021 taatggcaga acagacttta ttcccaatga ttatcctgca caaaagcttt ttgtggatta
    16081 catgaagtct caaaatccta acctcaatgt caaaatgagt gatgtgctgt ataatccgac
    16141 agcacagggc attatcatga gtaaaaaaga tgacaccctt aagaaaaaga ttgatgcggt
    16201 catcaaagac atgaaacaag atggcagctt gaaaaccatt tcaaagacat actatgctgg
    16261 tcaggatttg acagttcctt ttggtaagga caagaaaatt ccagtcattg atgccagtga
    16321 tgtggactag tgccttagac aaaggagctc taaagcgatg cttaatctta gattgatact
    16381 agagagcttg ggctttgttt tgtcaggttt gccctatacc ttaggcattt cttttttaag
    16441 ctttctaaca ggccttttgc tgggcttgct tttagccttt ttaaggcgtt ctactagtca
    16501 ctttagtcat tatctggtca ggagctatgt gtccataatg cgtggcgttc ctatgattgt
    16561 ggtgctcttt gtcctttatt ttgggcttcc ctattatggc ttagaactgt ctgccttgtt
    16621 atgtgcctat ttgggctttt cactggttag tgcagcctat atctctgagg tctttcgtgc
    16681 ctcgattgat gctattgatc agggacaatg ggaggcagca agggctttgg ggctgcctta
    16741 tgtcagcatt gtcaagcatg tgattctgcc tcaggccttt cgtattgcta ttccgccttt
    16801 aggaaatgtt gtgattgata tggtcaaaag ttcgtctttg gcagctatga ttaccgttcc
    16861 tgatattttt caaaaggcta aaattattgg tggcagggag tgggattaca tgtctatgta
    16921 tatcttggtt gcctttattt attgggtgat tgcctttttg ctggagcgct gtcagggctt
    16981 tttagaaaag aggctgcgct tactctctta aaaaccgaat atttacccta gaaatattgt
    17041 atttctaggg tttttatgat aaaaatatga tagactaaag tagcctaatc agttagttag
    17101 ctttgtcaag aactgactgg ctagagtgtt ggaggtagga tatggcagac tctattgtat
    17161 ttcggaaaaa tcatatgatt tcaactcagg cctttgctcg agtgctggaa gcctcaggga
    17221 ttaaaagacc gactaaggac gaggctagat tatcgcaaat gctaaagcat tccaattatc
    17281 tatggacagc atgggaaggt gacaagttag ttggtgttgc tagagccctt actgactatg
    17341 cttatgtctg ctatatttct gacctagcag ttgatcaggc atatcagggt caagggatag
    17401 gcaagcaatt gctgtctttt atctcagagg atcttggaga tgctgttgct cttgtattgc
    17461 tgtcagcacc ttcggcgatg tcctattacc ctaagcttgg ctttgaacaa tcagacaaag
    17521 ccttcattat tccacgaaaa ccgttttaga gaggtatcta atgacacatt cagcttggca
    17581 tgatgagatt aagcaagtgt tacctaagga ttattatcgg cgtatcaatc gctttttaga
    17641 tgaggtctat gcgactggag tggtttaccc gcccagagac aatgtgttta aggccttaca
    17701 ggtaacgcca ttagaagaga caagagtgct tattttaggg caggaccctt atcatggccc
    17761 tcttcaagct cagggacttt ccttttcagt gcctgactcc attcctgctc cgccatcttt
    17821 gcaaaatatt ttggaggaat tagcagcaga tattggagta aggaatcatc acgatcttag
    17881 cagctgggct gagcagggag tgttgctctt gaatgcctgc ttgaccgttc cagaaggacg
    17941 cgccaatggg catgcaggtc tcatctggga gccctttacc gatgcggtta taaaggtctt
    18001 gaatgctaag gataggcctg ttgtgtttat cctctgggga gcctatgcga gaagaaagaa
    18061 ggccttgatt actaatccga ttcaccatgt tatcgaaagc cctcacccta gccctctgtc
    18121 agcctatcgt ggcttttttg gcagcaagcc cttttcaaga gctaacgcca ttttagaaaa
    18181 agaaggccta ggacagattg actggctgcg ctaggcattg aggcaggcta ttatggctaa
    18241 gcaggacgat ttaccaataa agtatccggc tttggagact tgggtatacc tagctaaata
    18301 gagattgatg atatcaggga tcaagacagt tacgtccgat atgtcaagca aaacaaataa
    18361 tcactgccta gataaatcag aaattgctag ggttatgctt gattatcctg ataagcagat
    18421 aagtagattt gacataggag gggtcatgtt attaattaaa aatgggcgtg tgatggatcc
    18481 aaaatcacag ctagatcagg tggcagatgt cttaattgat aatggaagga ttttacggat
    18541 tgctccagac attgagcatg atgaggtaga gcagatcgat gccagtggac ttgttgttgc
    18601 tcctggttta gtggatattc atgttcattt tagagagccg ggtcaaacgc acaaggagga
    18661 cattcataca ggtgctctgg cagcagctgc tggtggggtg acaacagtag tcatgatggc
    18721 aaacaccaat cctgttatat cagatacgga aaccttacag gctgttctag caagtgctgc
    18781 taaagaaaaa attaacattt ataccaatgc tagtgtgacc aagcggttca atggccaaga
    18841 gctaacagac tttaaagcgc tcttagcagc tggtgcggtc agtttttctg atgatggcat
    18901 tcctttagag agctccaagg tcttaaagga agcattggat ttggctaagg ccaacaagac
    18961 cttcattgcc ctgcatgagg aggatcccca attaaacggt gtccttggct tcaatgagca
    19021 tatcgctaag gatcattttc atttttgtgg cgctactggt gtggcagaat atagtatgat
    19081 tgccagagat gtgatgattg cctatgatcg acaagctcat gttcatattc aacatttatc
    19141 taaggctgag tctgttaagg tagttgcctt tgctcagcag ttaggtgcca aggtcacagc
    19201 cgaggcaaca ccgcagcatt tttctaaaac agaagacctt ttacggcttg caggggcaaa
    19261 tgccaagatg aatccgcctc taagaacaga acaagataga ttagcagtta ttgaggggct
    19321 caaatcaggt gtcatagcta ttattgcaac ggatcatgca ccacatcatc gtgatgaaaa
    19381 ggccgttgct gatctgacca aggcaccatc tggaatgacc ggcttagaaa cctcattgtc
    19441 attaggcctg acaaatcttg tggagccgag ccatctttca ttgatggcgt tattagagaa
    19501 aatgaccatt aatccagcct cactatatag ctttgatgct ggttatttgg ctgagtctgg
    19561 ccctgctgat cttgttattt ttgctgacaa ggaggagcgt ttggtaacag aagcctttgc
    19621 ttcaaaggct agtaattcac cttttattgg cgaaacccta aagggagttg tgaaatacac
    19681 cattgctaag ggacaaattg tttatcaggc agacaactaa tcaacactta aaaagctgag
    19741 catctgatag taactgatgc tcagcttttt gatttagtga tggcttgcgg gctgctgctt
    19801 gcttaagttc aagccccaag gaatgagatt ttcagattgc tgcttgattc gcttcatatt
    19861 atcctgatgc cttaggataa tgattgctgc tagcacaacg atggtaatgg ttaatagcca
    19921 atcgtagcta ggcaataaaa agtgggcggc aggaaaagtc agaacgctaa tcacagctac
    19981 tacagacgct gttagactag ctagtgaaat catgctaaat aaataaagcg ttagcacaaa
    20041 cacagccgct aaaaaaagga gatagagtgg ggcaaagcct agcaagacac cagcactggt
    20101 tgcgactgcc tttcctccct tgaagccagc gaaaatagga aaggtatgcc ctaggacagc
    20161 aaaaaagcca atagtaattg gtgagatatt gctagcgcca accaaaaccg gaagaagcgt
    20221 ggcaagcgtg cccttaaaaa tatcaatcaa taaggttgca gcaccagctt ttagcccaag
    20281 aatccgaaac gtattggtcg taccggtatt acctgagcca tgctcacgca ggttgatgtt
    20341 atagaaatac tgtccaatcc ataagcctgt tggaatggag ccaagtaaat atgctgtaag
    20401 aattaatagg atcaatttca taacatacat tatatcataa tgattgattt aagcggaagc
    20461 agttacaaag aattacgaaa aaatcttaaa ttattttgca aaattctcaa aaaacctgta
    20521 agataaaaaa gatgaaaacg tctggaggtc aacttggcta agaaagaaat aagcataaca
    20581 aattataatg atgatgccat tcaggtccta gagggcttag aggcagttcg taaaagacca
    20641 gggatgtata tcggatcaac cgatgcaacc ggacttcacc atttgatttg ggagattgtc
    20701 gacaatgctg ttgacgaggc cttatctggc tttggaaatg agatcgatgt gacgctaaac
    20761 aaggatggtt ctgccaccat ttctgacagc ggacgaggca tgccgaccgg acagcacgcc
    20821 cttggtatac caactgttca ggtcatcttt accatcttgc atgcaggtgg taaatttggt
    20881 caaggaggct ataaaacctc aggaggcctg catggtgtgg gctcttcagt tgtaaatgcc
    20941 ctatcgtcat ggctagaggt ggaaatcacg agagacggag cggtttacaa gcagcgcttt
    21001 gaaaatggcg gtaggccagt gacaggctta gaaaaaatag ctacagctcc aaaaagcaaa
    21061 tcagggacaa gggttacttt catgcctgat gacaagattt tttcgacaac tgagttcaag
    21121 tggaatacta tcgcagagcg tctaaaggaa tctgcttttc tgctaaagac ggttaaaatg
    21181 accctgactg atctacgagg tgacgatccg gtcgttgagg aatttcatta tgaaaatggt
    21241 gttcaggatt ttgttgccta tctcaatgag gacaaggaaa ccttgactcc tgtgatttac
    21301 atggaagggc aggagcagga ttttcaggtt gaggtcgctt tgcaatacaa tgatgggttt
    21361 tcagataaca ttttgtcctt tgttaacaat gttaggacaa aggacggtgg cagccatgaa
    21421 actggcttaa aatcagctat tacaaaggcc atgaatgact atgcccgcaa aaccagccta
    21481 ctaaaggaaa aggataaaaa cttggagggc tcagattatc gtgagggctt gtctgcagtg
    21541 ttatcgatcc ttgtaccaga gcagcatttg caatttgaag ggcaaacaaa ggacaagcta
    21601 ggaagcccac tggcaaggcc gatcgttgag agcattgtat cagaaaagct gaccttcttt
    21661 ttacttgaaa atggtgagct ggcaggtcat ttgattcgta aggctatcaa ggcaagagac
    21721 gcgcgtgagg cagccagaag agcgcgtgat gagtctcgaa atggtaagaa aaacaaaaag
    21781 gacaaggggc ttctttctgg gaaattaact ccagcccagt ccaaaaatcc taagaaaaac
    21841 gagctgtacc tagtcgaggg ggactcagct ggaggctcag ctaagcaggg cagggatcgt
    21901 aaatttcagg caattctccc cttacgtggt aaggttttga acacagaaaa ggccaagatg
    21961 gctgatattc tcaaaaatga ggaaatcaat acaatggttt ataccattgg cgcaggtgtt
    22021 ggtgctgatt tcaatcttga tgatattaat tacgacaaga ttattatcat gaccgatgct
    22081 gatacggatg gggctcatat tcagaccctg ctgctgacct ttttctaccg ttatatgcgg
    22141 ccgctggttg aagcaggaca tgtctatatt gccttgcctc ctctttataa aatgtcaaag
    22201 ggtaaaggca aatcggagaa ggtttcctat gcttggacag atggtgagct ggaggatctt
    22261 cgcaaggaat ttggtaaagg tgcaagtctc caacgctata agggacttgg ggagatgaat
    22321 gccgatcagc tatgggaaac cacgatggac cctgacacac gaacccttat ccgagtgacg
    22381 attgatgacc tggctagggc agagcgacgc gtttcagtcc tcatgggaga caaggctgcc
    22441 ccacgccgtc aatggattga ggacaatgtc acctttacct tggaggaaaa tacggttttt
    22501 taaggcattt ttcctaagga gggttctaaa atatctcata tcaaattgct attcatgtgc
    22561 tcagcattca tttatcaagg attgtaatca ttgaggtaac agtgatgaag ctagatattt
    22621 gtcaacaaag ctacagtctt cagtggggag gcacctatta ttttgcattg acagattatc
    22681 ccaatatcaa ggcttgggaa ctggaaaagc tagcagcctt ttgtgcctac gaaaaatgga
    22741 atcatcgtca aacagacatt agctgtcagg acagcaagct tcttgaagag gttcatcaat
    22801 ttcttgaagc acatgcttgt gcctatctct ttaggcctag ctgtaaattg gtggcttcaa
    22861 catttaacat caatggagag gcagtctgtt gtccttattt aagtcatacc tgcactgtag
    22921 cggctgctct aagcattttt aagacaggaa ggctattgtc tgctgtaaga gcttttgggg
    22981 taacggcaca ggagttggct aggagtgatc gaaatgctgc tggtgatcct gctgattatt
    23041 ttcattatgt gatgcttggc tggtccaata cgacctcagg ctatcgcttg gctatggaga
    23101 gattgcttaa tcgtatgcca aatgaaaagg acttaagaga gcattttgta cccggagtta
    23161 gctttcacta tagctattct gatatttgtc agatgaaagg ctatgttttt gatggctatc
    23221 accctgccaa gatcaaagac gagcttagtt tggaggaatt gcaggcttgc attattccta
    23281 aaagctggca gcagcgcttt gaagcaatta ttccaaaggc cttacgctca agggttcatt
    23341 acctagacta taaaggcgaa ggcttggtcg agtggtctga tagggtttat cagctgttaa
    23401 gagtgatcag tgacagctag ctgtaaatag gctagcttta tactattttt tgaatataat
    23461 agacaatcta acagaaagga aagctcagtg agaggtctct tgctgggtgt gggatggatt
    23521 tcctagaaac tgctaatcct agcgataggg gagcgtagcg agcccattct gaaagctcct
    23581 gccgtagtga aaagaagata atcgcttacg attatcttcg agggaaattt cgagccgaag
    23641 tctcgaaatt taggaatgga accgtaggtt cgcttctgtc cccactacct aaaggaactt
    23701 tcaaaaaaaa ctaattaaag aaagagatat ctttctgaaa gaaacaaaga aaggaatgtt
    23761 cagctagttt actaactgaa cacgggacta tttttcctag aaaaatcggt aacctcctag
    23821 tgtccaagga cacgtcgtca gttccagcat tttttacgga aaaatttcgc aagcgaaacg
    23881 tccctttgta tcttatgagt aatattcaaa acatgtccct tgaggacatc atgggagagc
    23941 gttttggacg ctactccaaa tacatcattc aggagcgagc gcttcctgat attcgagatg
    24001 gtctaaagcc tgttcagcgc cgcattcttt attctatgaa taaggacggt aatacctttg
    24061 aaaagggcta ccgcaagtca gccaagtctg ttggtaatat catgggcaat ttccacccgc
    24121 atggagattc ttcgatctat gacgctatgg tacgcatgag tcaggattgg aagaatcgtg
    24181 aaattcttgt ggaaatgcat ggcaataacg gctcgatgga cggtgatcca ccggcagcta
    24241 tgcggtacac tgaggcaaga ttatctgaaa ttgctggtta cctgctacag gacatcgata
    24301 aaaaaacagt gccatttgct tggaattttg acgataccga aaaagagcca acagtattgc
    24361 cagctgcctt tccaaatcta ttggtcaatg gctcatcagg gatctcagca ggctatgcta
    24421 cagatattcc accacataat ttgtcagagg tgatcgatgc tgttatttat atgattgacc
    24481 acccaaatgc caagctggat aagttaatgg agctattgcc gggtcctgat tttccaacag
    24541 gtggtattat ccaaggagca gccgaaatta aaaaagccta cgaaacaggt aagagccgcg
    24601 ttgttgttcg ctccagaact gaaattgagg atctaaaggg aggcaagcag cagatcattg
    24661 tgaccgaact tccttatgag gtcaataaag ctgtcctagt taaaaaaatt gatgatgttc
    24721 gggttaataa caaggttcca gacatagcag aggtgcgtga tgagtcagac cgtacagggc
    24781 tacgcattgc tattgagctc aaaaaagacg ctgacagcca aaccatcttg aattatttgt
    24841 tgaagtatac cgagcttcaa gtcaattata attttaatat ggttgcgatt gatcatttta
    24901 cgcctcgtca ggttggattg caaaaaatct tatcaagcta tatcgctcac cgcaaaagta
    24961 ttattatcaa gcgctctcag tttgacaagg aaaaggctga aaagagattg catattgttg
    25021 agggcttgat acgtgtctta tctattttag atgagattat cgcgctgatc cgagcttctg
    25081 acaataaggc tgacgccaag gaaaacctaa aggtcagcta tgatttttca gaggaacaag
    25141 cagaggctat cgtaacctta cagctttatc gactgaccaa tacagatatt gttaccctcc
    25201 agcaggaaga acatgaccta agagagctca tcacaactct ctctgccatt attggtgatg
    25261 aagcaaccat gtataacgtg atgaagcgtg agctaagaga ggtcaagaaa aagtttgcag
    25321 ggccgcgttt atcagagctg caggctgaaa gccaagcgat tgaaattgat tctgctagtc
    25381 ttattttgga ggaagaaacc tttgtcagtg tgactcaggg aggctatatc aagcgaacaa
    25441 gccctaggtc atttcacgcc tcaagccttg aggaaattgg taagcgtgat gatgatcatc
    25501 tgatctttgt taagcaggct aagacaacag accacctgtt actctttact aatttaggta
    25561 atgttattta ccgtccggtc tatgagctga ctgacttgcg ctggaaggac atcggggagc
    25621 atttatcaca ggctattgct aattttgctg ctgatgagct ggtgatatat gctgagttga
    25681 tccagtcctt tgaagaggga ctatatatct cagtgacaca gcatggactg attaaacggt
    25741 ttgagcgcaa ggagctgacg ccttggcgaa cctacaaatc aaaatcaatt aaatacgcca
    25801 agctaaaaga catagatgat cgcattgtgg caatagcacc aattatcatg gaagatcttc
    25861 ttttggtgac gcagcagggc tacgccttgc ggttttctag ccaagaaata ccgattcagg
    25921 gcctaaaggc tgccggagtt aaaggaatta acctaaaggc tcaggattac ttggtttctg
    25981 cctgcccagt caatgctgat tccttctttg tgctgacgca aagaggagca ctaaagcgag
    26041 tggcgattgc tgatattcca cagaccagcc gagctaacag aggtctgccg gtgttacgag
    26101 aattaaagac caagccacac agagttttct tggcaggaat ggtaaaagga gatactacaa
    26161 caggtaccat tgacttattt acacatgatt cagaggacac agctagtgac cagcaattag
    26221 aggttattag taagactggt caacaatacc agcttgctct caatagcctg tctctatcag
    26281 ataggacaag taatggctcc tttatttcag agagcatttc agatcaggag gtcgctgctg
    26341 caaggctcat ctagccaaag ctttttcgct gtaccagtga gggctctgag tctttcatcg
    26401 aaaaaagatg caaaacaatg aagaaaagaa tacaaaaaga aaagaggtag gataatgaca
    26461 acagctattg attgggaaaa cttaggcttt gaataccgta agctgccatt tcgctatgta
    26521 tcatattaca aggacggcaa atgggacgca ggtcgcttaa cagaagatgc taccctgcac
    26581 atctcagaaa gtgcaccagc tctgcattat gggcaacaag cctttgaagg cttaaaggcc
    26641 tatcgcacta agaacggctc tattcagcta tttcgcccag accgcaatgc agctcgctta
    26701 caggcaacag ctgaccgttt gctgatgcca caggtatcta ccgagcaatt cattgacgcc
    26761 gttaagcaag tggtaaaggc aaatgaggat tttgtaccgc catatggaac tggtgctacc
    26821 ctttacctta gacccttgtt aattggtgtt ggcgatatta tcggtgttaa gcctgctaac
    26881 gaatatatat ttatagtttt tgccatgcct gttggcaatt actttaaagg cgggcttgcg
    26941 ccgaccaact ttatcgtctc tgaggattat gatagagcag ctccttatgg cactggagct
    27001 gccaaggttg gtgggaacta tgcaggtagc ttattgccag gaaaagcagc taagacagca
    27061 gggtattcag atgtgattta cctagatcca gcaactcaca ctaagattga agaggtcgga
    27121 gccgctaatt tctttggcat cactgccaat aatgaattta ttacgccgct tagcccatca
    27181 atcttgcctt caattaccaa atactcctta ctccaattag ccgaagaaag gcttggtatg
    27241 accgctattg agggtgatgt gccgattaat gatttggacc gatttgttga ggcaggagct
    27301 tgtgggacag ctgctgtgat ctcaccaatt ggaggcattc agtatcagga taagctacat
    27361 gtcttttaca gcgagactga ggttggtcca gtgacacgtc gattatacga tgagctggtc
    27421 ggtatccaat tcggtgatat cgaagcacca gaaggctgga ttgtagctat tgattaaaat
    27481 aagtgaagct tgctattgca agctcttttg attttgtgta aaatagacaa ggcgaggtga
    27541 agtgatgagt aaaaaagaga aaaaaattga actgcaatta tgcgatcaac aagtaacagt
    27601 caacaatacc aagatagacg gttatcagtt acaaattggc aagcgtgtcg ttggcgagat
    27661 tgcagagctt gatggcaagt ttgctgtctt aaaagacagc acagtagatg ctttttttaa
    27721 aacattagag caagcagttg aaaatattat tgaaaactat aatttgaacc actaaaaatg
    27781 cttaaaaaga cttgtcagct tacaaaaact atggtagaat agtttttgtt gttacggaaa
    27841 gatagcgaag aggctaaacg cggcggactg taaatccgct cctttgggtt cgggggttcg
    27901 aatccctctc tttccatgcc taagctatta ggttcattgt tttaatgatg atattggggt
    27961 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
    28021 ccccagtcag aggtatcaga ttagcgtctg agatcgtcaa ggataaaagt tgttgtcatt
    28081 gcgggttacc ttgagaaaat atattgttat caaaagctag cataagctag cttttgttgg
    28141 aggatttttt agaatgaatg aatttgaaga tttgctaaac agtgttagcg aagtcaatcc
    28201 tggtgatgtt gtcactgcgg aggttttgac agttgataac ggtcaagcaa acgttgttat
    28261 tgaaggcaca ggtgttgaag gcgttttgac acttcgtgaa ttgactaacg atcgtgaagc
    28321 tgatattaat gactatgtta aagctggcga caccgttgaa gtgcttgttc ttcgtcaagt
    28381 tgtaggtaaa gatactgata cagttacttt cctagtatct aaaaaacgtt tggaagctcg
    28441 taaggcatgg gacaagctta ttggtcgtga aggtgaagtc gttactgtta aggggactcg
    28501 tgctgttaaa ggtggacttt cagttgaatt tgaagggctt cgcggattta tccctgcttc
    28561 aatgattgac actcgttttg ttcgcaatac agaaaagttt gtcggtcaag aatttgacgc
    28621 taaaatcaaa gaagttgatg cagcagaaaa ccgctttatc ttatcacgtc gtgaggttgt
    28681 tgaagaagca gctaagcaag cacgtgacaa agtcttttca acactttcag aaggttcagt
    28741 ggtaactggt actgttgcgc gtttgacaag ctttggtgct tttattgatc ttggtggtgt
    28801 tgacggtctt gttcacgtaa ctgagctctc acatgagcgt aatgtgtcgc ctaaatcagt
    28861 tgtttctgtt ggtgaagagg ttgaggtgaa ggtacttgct cttgatgagg aagcaggtcg
    28921 cgtatcacta tcacttaaag caacaacacc tggaccttgg gatggcgttg agcaaaagct
    28981 tgcacaaggt gatgttatcg aaggtaaggt taagcgcttg actgactttg gtgcttttgt
    29041 tgaggtatta cctggaattg atggacttgt acacatttca caaatctcac acaagcgtgt
    29101 tgaaaatcca aaggacgtgc ttactgtagg tcaagaggta actgttaagg ttcttgacgt
    29161 taacgctgct gatgagcgtg tatcattgtc aatcaaggca cttgaagagc gtccagcaca
    29221 agcagagggt gaaaaggaag aaaaacgtca atcacgtcca cgtcatcaaa aacgtgaagc
    29281 taagcgtgat tatgagcttc cagaaacaca aactggattt tcaatggctg acctttttgg
    29341 tgatattgaa ttataatact ataaaaa
//
LOCUS       DARYLJ010000031        29139 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYLJ010000031 DARYLJ010000000
VERSION     DARYLJ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29139
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..396
                     /locus_tag="TU746_001228"
     CDS             <1..396
                     /locus_tag="TU746_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891575.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            440..1105
                     /locus_tag="TU746_001229"
     CDS             440..1105
                     /locus_tag="TU746_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0891576.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGY
                     IIK"
     gene            1102..2079
                     /locus_tag="TU746_001230"
     CDS             1102..2079
                     /locus_tag="TU746_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0891577.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2179..3249)
                     /gene="xerS"
                     /locus_tag="TU746_001231"
     CDS             complement(2179..3249)
                     /gene="xerS"
                     /locus_tag="TU746_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL0891578.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
     gene            complement(3406..3843)
                     /locus_tag="TU746_001232"
     CDS             complement(3406..3843)
                     /locus_tag="TU746_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL0891579.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
     gene            4044..4736
                     /locus_tag="TU746_001233"
     CDS             4044..4736
                     /locus_tag="TU746_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0891580.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(5112..5588)
                     /locus_tag="TU746_001234"
                     /pseudo
     CDS             complement(5112..5588)
                     /locus_tag="TU746_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5801..7363)
                     /gene="guaA"
                     /locus_tag="TU746_001235"
     CDS             complement(5801..7363)
                     /gene="guaA"
                     /locus_tag="TU746_001235"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL0891581.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7650..8348
                     /locus_tag="TU746_001236"
     CDS             7650..8348
                     /locus_tag="TU746_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0891582.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            8560..8892
                     /locus_tag="TU746_001237"
     CDS             8560..8892
                     /locus_tag="TU746_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL0891583.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            8907..10478
                     /gene="ffh"
                     /locus_tag="TU746_001238"
     CDS             8907..10478
                     /gene="ffh"
                     /locus_tag="TU746_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL0891584.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(10631..11854)
                     /locus_tag="TU746_001239"
     CDS             complement(10631..11854)
                     /locus_tag="TU746_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL0891585.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
     gene            complement(12079..13050)
                     /locus_tag="TU746_001240"
     CDS             complement(12079..13050)
                     /locus_tag="TU746_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL0891586.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(13363..13803)
                     /locus_tag="TU746_001241"
     CDS             complement(13363..13803)
                     /locus_tag="TU746_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0891587.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(13800..14735)
                     /locus_tag="TU746_001242"
     CDS             complement(13800..14735)
                     /locus_tag="TU746_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL0891588.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(15173..15586)
                     /locus_tag="TU746_001243"
     CDS             complement(15173..15586)
                     /locus_tag="TU746_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL0891589.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(15684..16439)
                     /locus_tag="TU746_001244"
     CDS             complement(15684..16439)
                     /locus_tag="TU746_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL0891590.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(16444..18939)
                     /gene="gyrA"
                     /locus_tag="TU746_001245"
     CDS             complement(16444..18939)
                     /gene="gyrA"
                     /locus_tag="TU746_001245"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL0891591.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            19131..20114
                     /locus_tag="TU746_001246"
     CDS             19131..20114
                     /locus_tag="TU746_001246"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL0891592.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(20319..21686)
                     /locus_tag="TU746_001247"
     CDS             complement(20319..21686)
                     /locus_tag="TU746_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL0891593.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYGVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(21936..22538)
                     /locus_tag="TU746_001248"
     CDS             complement(21936..22538)
                     /locus_tag="TU746_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL0891594.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(22539..23516)
                     /locus_tag="TU746_001249"
     CDS             complement(22539..23516)
                     /locus_tag="TU746_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL0891595.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(23519..24778)
                     /locus_tag="TU746_001250"
     CDS             complement(23519..24778)
                     /locus_tag="TU746_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL0891596.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(24790..25221)
                     /locus_tag="TU746_001251"
     CDS             complement(24790..25221)
                     /locus_tag="TU746_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0891597.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(25235..25828)
                     /locus_tag="TU746_001252"
     CDS             complement(25235..25828)
                     /locus_tag="TU746_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL0891598.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(25800..26648)
                     /gene="prmC"
                     /locus_tag="TU746_001253"
     CDS             complement(25800..26648)
                     /gene="prmC"
                     /locus_tag="TU746_001253"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL0891599.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(26645..27727)
                     /gene="prfA"
                     /locus_tag="TU746_001254"
     CDS             complement(26645..27727)
                     /gene="prfA"
                     /locus_tag="TU746_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL0891600.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(27769..28338)
                     /locus_tag="TU746_001255"
     CDS             complement(27769..28338)
                     /locus_tag="TU746_001255"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL0891601.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            28525..28710
                     /locus_tag="TU746_001256"
     CDS             28525..28710
                     /locus_tag="TU746_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL0891602.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            28765..>29139
                     /locus_tag="TU746_001257"
     CDS             28765..>29139
                     /locus_tag="TU746_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL0891603.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         8615 a         6031 c         5494 g         8999 t
ORIGIN      
        1 tatgtcctaa ccggtggctt cctttttaca ggctttcttt taggcttgag ctttgtactt
       61 ggggctgcac tgatcattta ttacaagcaa tactctgaag gctatgagga taaaaaatct
      121 tacaatattc ttcaagaggt cggcatgagc aaacaacaag tcaaaaaaac catcaattcc
      181 caaattgtat tagtgttctt tatgcccata gctatggcag tcctacattt ttgtgtcgct
      241 ctggttatgc ttaagcaaat gctctttctc tttggcgttt tagacactaa tcttatttac
      301 ctagttagtg cgctgaccat tgctgttatt atcgttattt actttactat ttacaggata
      361 acaagcaaaa cctattacaa tattattgaa agataagacg agtggcgatt tttcgccact
      421 tttttgataa aataatatta tgattaaagc tggaaaaatt tatattgtcg aagatgacgc
      481 tgctatctta acacccttaa aagagcatct gagtcagaac taccaggttc ttaccgtctc
      541 taactttaga gacattaagc aagaggtgat tgattataaa ccggatatca tccttatgga
      601 catcacctta ccgtttttta acggctttta ctggacaaca gaaattcgta aaacgtcaac
      661 agtgccaatt gtttttatct caagcagtaa tgatgagatg gatacggtca tggcacttaa
      721 tatgggggga gatgatttca tctctaaacc cttttctcta accattttag acgcaaaaat
      781 cgcagccttt ttaagacgct cacagcaatt tagcagtgat gatgtgacca tagatcaatt
      841 taagctacat tttgatggca ccttatctaa tggcacagat agcattcatt tatcgccaac
      901 agagcacaaa atcttaacga ttttatttac tcacccgcag caaattgttt caaaggagga
      961 tattctagca aggctttggg aaaacgagag ctttattgat caaaacacgc ttaatgttaa
     1021 catgacgcgt ctacgcaaaa aaatatcagc tattggtttt gaccgtattc acacagtgag
     1081 aggagtaggc tatattatca aatgataaga gcatttttta aggaatatta ttcctggtat
     1141 atccagtatg gggttgttat ggctggttat ctgctgatct tttggcttta taggcttcct
     1201 ttaggctatt ttaaagtgac tagcctaacc atactaacct tgctaatatt gcaaggtttt
     1261 ggaaactata ttaggttcaa aaagaagatg aagattttac aagaatttat ttatgtaaaa
     1321 gaactagatc agctgcactc ccctagcgaa caagcctata ggtctttgat tattaagctt
     1381 aaggaagcag aagcagaggt agcactgtac caacttaaca accaaaagaa tacagaagca
     1441 ctgattaaaa tgtggtctca ccaaatgaag cttcccctag cggctatgtc cttaatgctt
     1501 caaaccaatc atattgatat taaggattat cagattcagg ttctacgctt ggagcattac
     1561 ctcaacaatc tattaagcta tttgaagttt aaccagcata gtgatgattt tcggtttcag
     1621 gtttgctctg taaagcagct tgtgacctca gttatcaaaa agtccagcca gacttgtatc
     1681 gctaagggga ttagcattgc agttgatggc gattggcaat tgagcactga caacaaatgg
     1741 ctgtcatttg ctctgacaca aatcattgac aatgcaatca aatattctaa gccacaaggc
     1801 cacatcaaag tcagcattaa ggaaggcagt atttttatat cagataatgg tattggaata
     1861 ctagaggaag atttgccacg tctgtttgaa gaaggcttta ctggctacaa tggccatgag
     1921 catcaaaagg caactggttt aggcctcttt atgacaaagc aaatccttga taaattaaat
     1981 ttaaacataa ctatttccag tcaagttgac caaggaactt tagttgtaat tcaaaaaaag
     2041 cattctaaac agaccaaatt ctcgacttct ttgctgtaaa aaataacagc tataaatccc
     2101 tataatagtg acaaagagga ttaaaacatt gcaaaaaaag actgaaagta cagattacat
     2161 aattttagtt atgtaaattt ataatttatc tagggcattt ttttgctcat cgttaacaat
     2221 atgagtatag aggtctgtaa cttgggtcga ggcatgacca agctgatgac ttactaggac
     2281 ctgtgacttt gtagtatcat aaagtctcgt tgcaagcgta tggcgtagct tatgaggagt
     2341 tacacgaatt ttaaagcctt cagaatattt acctaccatt ttttcaatgc ttgaggcatc
     2401 tatccgattg gggagcccac gataggctgt taaaaagaag gctacatcct gtttttctgc
     2461 ttgatagcgg tcttttcgaa ctgataaata ggcttctaaa tgaggcttgg caaaagcagc
     2521 aacattgacc gaatctctct tacctccctt acgggtaacc tcaaccagca tcatgttgag
     2581 gttgacatcc ttaaggtcta ggttaactgc ctcggataac cgaataccag atgccagcag
     2641 tagggcgata atggctaggt cgcgttcttt attttttcgg aaagaagcct ttgcccgatt
     2701 tgacagctta tattcatatt ctttatccac atagtctaaa aatgccatcg tctcatcgcc
     2761 taaaaaaagc ttttgtttaa tattttcagc cctggctgct aaggtttctc ttttcttttt
     2821 ggttgccacc tttttcatga catttcgata aaaataaggc tctccatgct cattttcaac
     2881 ctcctcagta aggtatttat acaagctgga tagtgcagaa agggtacgat taatggtggt
     2941 ttgcgatacc ccctttttag ttgaatagat gttcaaggaa ggacgctcac gaagatagag
     3001 aataaaggct tccatatcct ttttactcaa atgctccaga gtagtcaagt ccacatcagc
     3061 aatcctagca gcttttgata gatcagaatc aattaaccac tcaaaaaagc gtttgtattc
     3121 tttcaggtat tcgtacaagg tcgtaaagct ataaggaaca gatagcttag attgataata
     3181 atcaaggaca taccaaggca tgatgttttt gtattcttca attttagtaa gtagtaaatc
     3241 acgtttcata ataaattctc acaatgtttc gtcaacaaat gaattatcca ttggatatca
     3301 gactgatagt agtatatcac atcttggggt atttttcaag aaaattatag tttttcggaa
     3361 agatataaaa ttatttaata gttattttgc taagctaagg ctgttttatc tgctacgatg
     3421 ctgcttaaaa atatagtatt tactaacaat aaaattcaag ctaatcatta tggcttggct
     3481 caaaatgctt tcaacagaat taatgctttc agaatcatgt tcaacaaggc ttccaatgac
     3541 ctctgggtat ttttcgacta ataaataggc taatagcata tctaagccta atgttactac
     3601 tctagctagg aaaaacatgg caaatctaaa caagcgtttt tcagaagttt gcttaaaaac
     3661 atagctatcg ttcatcaaga aggcagctat gatcgctata atattggcaa agcctgctga
     3721 tatggtggcc tgatgtaacc atgaatagat gacataccga aaaacaaaat aaagaatggt
     3781 tgttagaaga ccagatatca ggtaatgact gatttcaagt gataattttt gtttgctaag
     3841 catttttctt tcctatgtgt atttatcttg actgttatat tttgatggat ctatataagt
     3901 ataacatgtt tggcattaaa cctaagacag cttactgtct tttcgatata aacataaaaa
     3961 gcttgaatat tcttataagc tatgttatac tctggtaaag ttaatacttt actagagtat
     4021 actgacaaag gagatttatg ctgatgtttt ctggtattca attaaaaaca gcacgtttat
     4081 caaggcatat tagccaagaa cagctaggac agcttttagg agttaataaa atgactattt
     4141 ccaattggga aaaggagaaa aatagaccaa atcaaaagca ttttgaagag cttgtgagca
     4201 tttttcaatt acctgctgag tacttttatc aagaaaatcg tcttttactt ccctatagtc
     4261 agttaagcgc ctctaataaa gaaaaagtta tcagctattc tgagagctta cttgaacaaa
     4321 aagaaaaaat aattgcttta ccagctaaga aaaagacact ttacccttat cgtgtttatg
     4381 aaaggttgtc tgcagggact ggctattctt actttggtga tggtaatttt gatgttgtct
     4441 tttacgatga gcagttagat tatgattttg cttcatgggt ttttggtgac tccatggagc
     4501 caacctattt gaatggcgag gttgttctca tcaaacagga tagctttgat tatgacggtg
     4561 ctatctatgc tgttgagtgg gaagaacaaa cctatatcaa aaaagtatat cgtgaagaaa
     4621 atggtctgcg tttggtttca ttgaacaaaa aataccctga taaattcgct tcctttgatg
     4681 acaatccgcg tattattgga aaaatcattg ccaactttat gcccttagat gtataagcct
     4741 ttgtattagc ttaaaagcat gactgttgta caaccaaact cattgcatga cattggtgca
     4801 ttatttttga agtggcttct acttctttga tttacttttc tgcattaaaa agcccattaa
     4861 aggtttttga aacttattac ttagacaaag gctctattaa aaatcataac caaccggtgg
     4921 tggtttattt gtcatgtacc ttgcattttg tgacagactt cataaaacga acaaaacaca
     4981 tcgctaaaag attttaccat cttaaagtta tgtgtttttt gtataaaaac ttatctatat
     5041 gcttgattaa ccaactgaga taaatagatt attatttcat agagaagttt gttatctaat
     5101 ccaaataatc gtattatcct cttaagttcc tcaacattat aaccatcaca atctgttggc
     5161 agtttatttt tttcaagcca cttatcaacc actgctattc ccaaagaaat tgaaaaatct
     5221 ttttctttat caaacttaca caattccact gccaaagtca atacaaaatt cctgtgaata
     5281 ttatcgtaat tttcatcaaa taattgcctt tccaaaccca caatagatag ccgactaaat
     5341 atgtatctcc ctatttcttc gtcaatacct tcagtagcct taatagcttc ttggacaaca
     5401 ttattccaga aagcattttt attacgctct tctataaaag ttttaagttt cattttgaaa
     5461 atatcagtaa tttgaccaac tgctttatca ataacctatg aaacaatatt cttcatcatt
     5521 atgattttct cctcgtatac ataaataatt gtatctttgc tatataattg tggtatctct
     5581 tcaatcaacc aatattgttc ttaaactatt ccctcaaaag ccttccacca aaacgatgga
     5641 aggcttttaa accattcacc taaattcaac aactcccttt tgaacttgct attttagctt
     5701 tttagtatca aagcagtatc actcaagagt tttttgtttc cacaaaccgc aaaaacccac
     5761 tgttttcaac actttcatgg cagtaatata tttgcttctg tcactcccac tcaacggttg
     5821 ctggtggttt gctggtgatg tcgtagacaa tgcgattaac gtggtcgact tcattgacaa
     5881 ttcgaactga gattttcttt agaacttccc aaggcaattg ggcaaagtct gctgtcatac
     5941 catcaattga ggtgatagca cgaatagcga tggtatagtc ataggtgcga ccatctccca
     6001 taactccgac ggaacgaaca cctgtgttaa ctgtaaaata ttgccacaca tcacgctcaa
     6061 gtcctgcttt agcaatttct tctcgaagga tagcatctga ctcgcgaaca gtttcaagct
     6121 tttctgctgt gatctctccc atgacgcgaa tggcaaggcc tgggcctggg aaaggctgac
     6181 gccagacgac ttcatctggc ataccaaggg ccgtaccaag agcacgaacc tcatccttaa
     6241 agagtgtatt gaggggttcg attaattcaa actgcatatc ctctggcaga ccaccaacat
     6301 tgtggtgaga ttttatcgtt tgagcagttt ctgttccaga ttcaatgatg tctgtgtaaa
     6361 gcgttccttg tgcaaggaag tcaacgccct taagcttgct agcctcgtca tcaaagacgt
     6421 aaacaaactc attaccgata attttacgtt ttttctcagg atcctcaacg cctgcaagaa
     6481 gatctaaaaa gcgctttgag gcatcaacac gaataatatt gagaccaaat cttccaccaa
     6541 gcatttccat aacttggtca ccttcatttt tacgaagaag tccatggtca acaaagatac
     6601 aggttaattg atctccgata gctttttgta aaaggacacc aacaactgaa gaatcaacac
     6661 caccagacaa acctagcaaa accttacgat ctccgactgt ttcgcgaatt ttagcaattt
     6721 gcatgtcaat aaaattatcc attgaccaat caccacgtcc accacagata gagatagcaa
     6781 agttcttcaa aatatcatta ccatagacag agtgtcttac ctctgggtgg aattggatac
     6841 cgtagagcct cttttttgta ttttccatag cagcgtaagg gcaatcgtta gaatctccta
     6901 caagatgaaa gccctctggg atttctgtaa cagcatcacc atgactcatc aaaacaagct
     6961 gctcatctgg agtgcccgca aataatgctg atgcagaacg taaacgtaat gatgattgac
     7021 catattctcg gtgacctgct tgaccagctg ggactacctt acctcctaag gtatgtgtga
     7081 ttagctgcat gccatagcaa atccctaaaa ttggaatccc taattcaaag atttcaggat
     7141 caataccaaa ggcatcagtt gcataaacag aatttggccc accagacagg acaatcccga
     7201 ttggattgat gtcacgaagc tcttgcgcag tgatgtgatg gcttttgagc tcagaaaaaa
     7261 caccaaactc ccgaatacgt cttgcaatca gttgattgta ctgactacca taatcaagaa
     7321 cgataatttt ttgaatatca ttcaacattg aaatttcagt cattataacc ctttcattat
     7381 ataccagaac cttgttagct gatagttttc aattaattgt agcatatttt cactaaaaag
     7441 gcattagctt ttcaggtgat gtgatgaaaa aataagcttt ttgcagagat attaaaatga
     7501 atgacctcaa ctatcttatg tatgactact attgtcagtc ttagcatgaa aaagctgatt
     7561 gatgatgagt gtttttggta ataattgggc tgctatttag gctgaaaata tgataaaata
     7621 aaaccatcat caccctcaag gagtaaagca tgctgccagc ttatataaaa attcatgacg
     7681 ctattaaaaa agacatcgaa aaagaagttt ggactattgg tagtcgcctg ccaagcgaac
     7741 gagatttagc agaacatttt gaggtcagtc gcatgacgtt gcgtcaggca ataacactgc
     7801 ttgtagagga gggaattcta gaaaggcgtg ttggtagtgg tacttatgtt gccagccatc
     7861 gcgtacaaga gagaatgcgt gggaccacta gctttacaga gatcgtgaat tctcagggac
     7921 gtaagccatc ttcaaaactg atttcctatc aacgtcagct agcaagtgat acagaaataa
     7981 atcaattgca cttagaagaa tcagattacg ttattcgaat ggagcgcatt cgttatgcag
     8041 ataaggttcc cttagtttac gaggtagcat ctattcctga gaaatttatt aaaaatgtca
     8101 aaaaaactga tattacagag cactttttcc aaaccctaac ctcaaacggt tatgaaatcg
     8161 gcaaaagtca acaaaccatt tacgcgaaaa tagccagtga gcgtgtcgcc tcttatctag
     8221 aggtcgctaa ggggcatgct attttagcat tgactcaggt ttcctttttt acagacggta
     8281 ggccctttga atatgtgcgt agccaatatg taggtgatcg ctttgaattt tatttagaaa
     8341 ataattaatc ataagcaatg atgtttaaat aacattgata ggaagtggct caccacttct
     8401 ttttttcaac acttgtcaag tatatcaata tttcaagaac agttattaaa acaagctact
     8461 attatcctca tttttgctct aagaaagctt cctgataaaa ggctgatcgc tatcatttac
     8521 cactgttaaa aatgctcatg atgtgataaa atgaagatta tggaaattga aaaaacaaac
     8581 cgaatgaatg ctctttttga attttatgct gccttattga ctgataaaca gatgaactat
     8641 atcgagctct attacgctga tgattatagt ctggctgaaa ttgctgaaga attcggtgtc
     8701 agccgccaag cagtttatga taatattaag cgcactgaaa aaattctgga agcctatgaa
     8761 atgaagcttc atatgtattc agattatatt gtacgtagtg aaatatttga tgatattctt
     8821 gcaaaatatc ccagtgacca ctatttacgt gacaaaattt ccattttaac tagtattgac
     8881 aacagagatt aagaggagtt atagctatgg catttgaaag cctaacccaa cgtttacagg
     8941 acgtttttaa gcacattcgt ggtaaaaaaa ccttatctga agccgatgtt caggaagtga
     9001 ccaaggagat tcgtctagcc ttattagagg cagatgttgc acttccagtt gttaagacct
     9061 ttatcaagcg tatacgtgag cgagctgttg gccacgaaat tattgatacc cttgatccaa
     9121 cgcaacaaat acttaaaatt gttaatgagg aattaactgg tatcttagga tcagaaaccg
     9181 cggagcttga taaatcacct aaaatcccta ctgtcatcat gatggtgggc ttgcagggag
     9241 ctggtaaaac gacctttgca ggaaaattag ccaataagct catcaaggaa gaaaatgctc
     9301 gtccattgat gattgcagca gacatctatc gtccggctgc tattgaccag ttgaaaacct
     9361 tgggacagca aataaatgtt cctgtttttg atatggggac aaatcattca gcagttgata
     9421 ttgttgccaa tggtttggca caggcaaaag agaaccgtca tgactatgtt ttgattgata
     9481 cggcaggacg gttacaaatt gatgagaaac taatgggcga gcttcgtgag gttaaagcac
     9541 tagctaaacc aaacgaaatc cttcttgttg ttgacagcat gatcggacaa gaagctgcca
     9601 acgttgccta tgaatttaac aatcagctcg atatcactgg agtagtgtta acaaagattg
     9661 acggtgatac tcgtggtggt gcggcccttt ctatacgtga aataactggt aagccaatca
     9721 aatttaccgg aactggtgaa aaaatcaccg atattgaaac cttccatcca gaccgtatgt
     9781 caagtcgtat cttgggaatg ggagaccttc ttaccttgat cgaaaaagca agtcaggaat
     9841 atgatgagaa aaaatcatta gagcttgccg caaaaatgcg tgagaatacc tttgatttta
     9901 atgactttat cgagcaatta gaccaagtgc aaaacatggg gccaatggaa gatctgttaa
     9961 aaatgattcc aggtatggca actaatcctg ctctagccaa tattaaggtt gacgacaagc
    10021 aaattgctcg caagcgtgct atcgtttctt ctatgacacc tgaggagcgt gagcagccag
    10081 agcttttaac accaagtcgc cgccgtcgca ttgcagctgg atcaggtaat agtttcgttg
    10141 aagtcaacaa atttattaaa gattttaacc aagccaaagc catgatgcag ggtgtcatgt
    10201 caggtgatat gactaaaatg atgaaacaaa tgggaatcaa ccctaataac ctccctaaaa
    10261 acatgccaaa tatgccagga ggcatgcctg atatgtctgc ccttgaagga atgatggggc
    10321 aaggtggttt acctgacatg tctgcattgg gtggtgatat ggatatgagc cagctctttg
    10381 gaggtggtct aaagggtaag attggtcaat ttgccatgaa gcaggccatg aagcgtcaag
    10441 ctaataagat taaaaaggcc aagaaaaaac gaaaatagac taaaagaatg gttgccttgt
    10501 attctgcctc taatcgttag atgctattct aatttggagt gcaggtcagt agcgaccatc
    10561 ttttttataa atacaatcac tagatctttg gttctaacca ttaaacatga tatcatttca
    10621 ctattagctg ttagtgcctg tgctttaatt gctttctgat cttatatagc aaattagcca
    10681 agtgataaaa aggactgatt gctaggttga attctccaat aaactcttcg atagttggac
    10741 tgaaattgga cttaaatgct gtcaatccgt ccttgaagga gccatcaatg ccgcccatat
    10801 tcgcccaagc tatatcatca tgataggcat ccataaagac tttaggataa agcaggtact
    10861 gaggataaaa ctttttaaag tcatcattca tgccagcata gagcatttcc atcgtgttgc
    10921 catatgaaat cgataaaatg cccgcaatga caacctcatc tggatattta tccaagaagt
    10981 ccttgaattc tgatagataa cgctgaagcg attgcttttg atctgttagt ctagccagtc
    11041 gctttttttg atgcgcttgc gtttgagcaa gctcttgttc aacagctttc agctgaagct
    11101 cgtaattctt gagtttttct ggaagattaa cctttgctaa atgcaaataa gcattgtcgc
    11161 cataagtcgt catcagctgt ctaaaataag cttcgtttct tagagcaact ccttttctct
    11221 tttcagttaa agagataagg tcagcaaatg tatggagatc agactgatta cctcgataag
    11281 ctatcacgcc acgttgccta gcatccttca tcaatcgctt ggtatgctta ggaaaggacg
    11341 cttcaatatc agcattagtg taacaatttg cttgaaaacg cggctgaata gtatcagata
    11401 gcttggttgt tgggcctgtc caatgggcac caaatcgctt taaatgctta ataatggtca
    11461 gagccttgga attatcaggt gctttctcac caagctgatg ctgctttagc agaatcatag
    11521 gatcaaattt aatcaaaaga gctctttttt tcttaccata tgccttcaag gttttaatcg
    11581 taaatgccac tagatcagca ttggtatagt ccatcactgg acctcttgga atataaatca
    11641 tcgtcatacc aaacggcaaa ggcttaatca gcaaggacat agaagccacc tgattatctc
    11701 cctgaaaaat accgatgcgt tcattttgcc actgattttt aacagctgcc catgagctgc
    11761 tctgcaagag gttaacctgc tggtgctgtt tgacaaattg gtcatgctct tgagctgaaa
    11821 taccgatttt tgaattaaaa gctacattta tcatcatatt tcctcatctt taagtatcta
    11881 aatatctgat cttgaaatag atctgcttct acttaattta ttcgaaaaat agtttgaaaa
    11941 ataattgctt tttttgattt tcaatttgat tatttttagc tgctcaaatg aataatcgat
    12001 ttcggtttaa ataagtttaa aaaataggac taattcctaa tgaaatcagg aattagtcct
    12061 actactttta tctatttatc agttacccat taggctgtca atcaatcctc taaagaaatc
    12121 aataatttgc tgaaggattc cctgtccagt ctttaaggct tcagtagcat caaagttcac
    12181 gttgatattt ttaaaggtag atccggcctt ttcaacaata ctatccttta aagcattcag
    12241 cgttttggtg aagttttcat tggaaatcac gccactattt gagaggttaa gcgcgaaatt
    12301 gataataagg ttaatctgat caggtgttac tgccttggtt aacccataat gatctaaggt
    12361 ttctgttaca atttggcgca ccttttcctc attaacccct tctccagcct ttgcgacagc
    12421 agctttaata tcagtaagcg caacatttag cttatctgca tcatagcctg ttttacctgc
    12481 attttcggta ttgatattag atagggttga tagctcctct tgtgccagct tcttgttttc
    12541 ctctgggact ttggcaccat ttttttcgag tgaataataa ataccggcta aagctgattc
    12601 tccagtaact gggattggtg cagctacagt aatattggca tgctcaatgc ccaaggtcac
    12661 agcggcgtta cgatacatat cttgcgtcac cttagtgata ttttcaggtg ttacaatagt
    12721 taccttaagc gtttctttag ctcccagctt ttgaatccta actgaggaat aaagctgtag
    12781 gctcggatca tctgctacat tcatgatact agcataggca gttgtattta gggtgcttaa
    12841 tttgttatca gaagcactat tgtagtgaag caaggccaag gtttgctctc tttgctcagc
    12901 agacagtgaa tagcctaaaa cgtaatcagg ctgaacatag gtttcatcaa ttacctgttg
    12961 aacattatta gctgcagcgt gtactgtttg aagcataaat accgaagcca aagccatact
    13021 ggctgctatt aatttctttt gataagtcat ttttctacct cttttgtgtt ataaattttc
    13081 ctttacgaga atcctccaga aaagacgatt aaagccaaag tatctaggtg cctagtaaga
    13141 ccgttttact tagctctgca aagggcaata ttcctagtct ttttcaaaat ctaacgcctc
    13201 tattgtagca tttttacctc aataagacga ttaaaaagct gaaacaaagc atagctagaa
    13261 tggccaagca ctatttttac aacaaaaaaa ctagtgcata atggcagctt agatgtagct
    13321 actatcacta gtccaatgat tatcttatgc agcaaccagt ctttatgatc tgaggttttc
    13381 ttgatggtta ttgtccttta aatagaaata ataatgatca tcagttttga tgacatagcc
    13441 atttttaacc tcattaatca cgtccttttg atcaaactgg tagtccttag gcggtaataa
    13501 ctctgaggaa aaaaggctat cataaggcac ctcaccattg taaaaatggt aatggtcacc
    13561 atgagaggta acaaaaccat catccgagat agacacaata atttgctctg ctgctatccc
    13621 ctcttccttg ctaacttcat taggactttt gtcagtctct ttctttaagg ctttgcacct
    13681 tttttccaat tgatgagatg attttagctt cttgcctgtg ctatcttggg ctttaaagtc
    13741 acaagcggac aaaggaaata atagtaagat agtgaataac gataaataag cttttttggt
    13801 catgtttcac tctccaatac acgatatagt gtttctaaat tcatttttaa atgctctaga
    13861 taagtttttt gatcagctgg aaccacctca agcgggctta ggatatcaat tgctacaccg
    13921 ttactttgag ccaaggtttt ggctagctta tctgaagcat tttcttcgac gaaaatcgtc
    13981 ttcacatcat attttttgat aaagcggtca atttgagcta attggcgagg actaggctct
    14041 tgctcaggag atatccctgc aattcccaat tgctttagat caaatctctt agctaggtag
    14101 gaaaaggctg tatgctgtgt cacaaaggtt ttcctaccta gagattcaaa cttttcctta
    14161 taggtcttca ctaatttttg agccttagcc ttaaaacgct tagcattttg caaataaact
    14221 gccttgtgag caggatcttt ttgactcaat aaagctgcaa tctgctctgc ctcttgacta
    14281 gctaagatag gatcagtcca agtgtgagga tcatacaagg catcggtatt cattcctttt
    14341 tttatggtga agtgctccaa gccttgaacc ttgtctaatg ttagatgtga tgtcccctcc
    14401 atgactgcta atcccttttt ttccagctgt ggtgccaaat ccgcagccca agcttctaat
    14461 atcttggaat ggtaaataaa gacatctcca tcgtaaacct tagcaacaac tgtcggactt
    14521 ggctcatacg agtgtatgct agtgttttgg gcaatgacct gaacatcatt taaatccccg
    14581 caaatctcct ttgtcatagc ataaatagga taaaagcttg tttttatgac caaaccggcc
    14641 ttcctactgc tagagctctg atgacaggct gatagaccca aaagtactgc taatagtcct
    14701 actgcgacaa ttgttttctt gaatcctcta atcatatcta ctctcttaac tagttaatga
    14761 cctaaaaagg ataccatgat ttaactgaaa tgtcaatatt ttatcatttt agcgcacgac
    14821 gtacacgcat gaagaaaatg catgtaagcc ttttttagcc ccatgcattt tttaatctat
    14881 ttctagcgtt ttgacattgc aatatcatca gtttgtcaat ttcaatgtga tgacttcatc
    14941 acattttgct aaaaaggcca tagtgatgat aaaaaaccgc taccagaaag cgtaaatgtc
    15001 ttcttgcttt tgtcgtgatt ttagtgaacc gcctaccaac tgaactgatg ctggcttaac
    15061 catttcctgg ccaccatcaa aagcctgcct ctcaattaac aagcttactc aaggaagagg
    15121 tgactgagcc atgcatccgt cttagttatg actaacagct tatcttggca tttcattcat
    15181 gtaattccag tggcaggcca tcaggatcaa aaaagaaggt catcttctta ccagtataat
    15241 catcatacct aagaggctcg acagcaatgc ccttagccat taattgttca atataagctt
    15301 caataggctt aacatgaaaa gctaaatgac gaagcccaca ggcctctttg tcatattcgg
    15361 gcctaccgat acgcttaggc ggtgcctgat aagctggatc agtcttttta ttgccaaaaa
    15421 tctctaattc aatggctcca cattttaaat ccaatttgta atcatgtcta tcaggccggt
    15481 gattttcacg aataatctca aagccaagct tattgacata aaaatcctta gagacctcat
    15541 aatccgaaac aatgatagca atatgatgaa tagccttaag ctccatatga tttagttcct
    15601 ttattaaata aaaaaagtga aacaaagcaa tgccaagatt actttgtttc acccctcgta
    15661 gcgacccctc gcctagatta ggcttaggtt gacatctgat tgtaagagtg attaaaggcc
    15721 ttcaaaacat cgtcaggtgc tttgttaaac tcatactcgt ttttgattgc tcctttgaca
    15781 atgattcgct ctgttgcctc ataatccgta caggtgacca aggttacctc ctttagccct
    15841 ggtgtgtcat tgataacatc tattctctca ggtgtgaccg taaagacggc attgatctcg
    15901 tactcgtaaa tacgctcctt atctgtaagg taaatagaca tcccttcttt tgctctttca
    15961 agcggtgaga ataacatttc agaagagcct gttagtccaa aaatatgatg actggctaag
    16021 gagtaattgt tttctcctcc cataacctgg tcctctttca tggtaccagc accgtatata
    16081 agctctgtgt tgccaagccc tttaaagatt ggtaggttaa taccaagctc tggtatggca
    16141 atacctccta ttactggaag ctgctgggcg tccatttgag cctgtaagac actttcggtg
    16201 ctaactggct gaactgcttg aaaatcaaag cttgactttg cttccttatt ctttttaatc
    16261 gtcttttttg aaacctttgt aacttgatat ttattagaat tccaagcaat cagggtgttt
    16321 ctaatgggct tgttaaataa caaggctaag cctatgatta acaataagac gactagaata
    16381 cctctagcaa aggacatctt tcttcgtttt tgtcttctcc tgtgggttct ttttgccatt
    16441 catttactcc ttgctagaat ttattggtgc ttctgttaaa gctgtatcag tctgagcgat
    16501 tgctgttgga tcgttgtctt cagcctgtac caaggtaaag gtaacaatct tagaatctgt
    16561 atctagcctc ataaccttaa caccaagtgt tgaacggcca gtctgagaaa tacttgaaac
    16621 attggtacga ataatcacac ccttcgttgt gatcaccata atatcctcac tgccatcaac
    16681 agtcatcagg ccagccaact ggccattttt tgcggtgata ttagctgttt tgattccttt
    16741 tccacctcga cccttagttg ggtattcggc tgcactggta cgcttaccat agccattttc
    16801 ggtgatgact aagacctctt gcttgtcatt gatacgagaa gctccgacaa cccaatcttc
    16861 ctcacgaagc ttgacaccac gaacacccgt agcgctacgc cccatgcctc gaatggtagc
    16921 ttcattaaag cgaacagaat aacctgatct tgttccaatg ataatatctt cctgaccatt
    16981 tgtcaagaga acattaatca gctcatctcc ttccttgaga ttaagggctc gtagaccatt
    17041 ctgacgaata ttgctaaact ctgatacctc agttcgtttg acaatccctt gctttgttgt
    17101 aaagaagaaa tatttatcaa gaatgtcttc ttttttagca ttgataattg tttgaatggt
    17161 ttcaccatca tctagcttta gtagattgat aacaggaagt ccttttgcag cacgtccata
    17221 ttctggaatc tcataggcct ttaagcgata gacgcgccca aaattggtaa agaaaagcaa
    17281 tgtgtcatgt gtacttgttg agacaagctc acgaacaaag tcatcgtcat tgacacctgt
    17341 tccctgtaca ccacgaccac cacgcttttg agatcgaaac tcgtcttgag caaggcgctt
    17401 aatgtagcca ttgtttgata gggtgatcaa aacatcttct tcctcgatca aatcctcatc
    17461 ttctaatgac aatacctcac caatcatcaa ttctgtgcgg cgaggattag cgtacttgcg
    17521 cttgatctcc tccatttctt ccttgatgat ggcttcgata cgctctggcc ttgccaaaat
    17581 atctgccaaa tctgcaatca aagccagtag gtcatcgtat tctgattgaa ttttatcacg
    17641 ttccaagccg gtcaaacggc gaagacgcat gtctaaaata gcctgacttt ggcgttcaga
    17701 caagtcaaaa cgagacatca attctgcttg tgcgataata tctgtctcgc tattgcggat
    17761 aatggcaata acctcatcta gatggtcaag agcgataagt aagccctcta aaatgtgtgc
    17821 cctagcttct gccttgtcct tgtcaaattg agtcctgcgt gtaatgacgt ccttttgatg
    17881 tagaatataa ttatcaataa tctgtctcag tgacaagatt ttaggaatcc cgccttcaat
    17941 ggctagcata ttgaagctaa agtttgtctg gagacttgtc aatttgaata ggttatttaa
    18001 aatcacatta gcagatgcat cgcgacggac ttcaatgaca aatcgtaccc cttgtcggct
    18061 tgattcgtca cgaacagctg taatgccctc aatacgcttt tcttgggcta agcgaacaat
    18121 atgctcatgg acctttgttt tattaatgcc ataagggaat tctgtgacga caatccgctc
    18181 ccgtcctgta ctagtggttt caatctcggt gcgtgaacgc aaaacgattg atcccttacc
    18241 agtctcataa gccttatgaa ttcctgaacg tcccatcacc aaggcacctg taggaaaatc
    18301 cggccctgga agaacctcca ttaaatctct ggtagtgcag tcaggatttt ccatgaccat
    18361 cttaacagcg tctatggcct cagctaaatt atgaggtgga atattggtag ccataccaac
    18421 tgcgattccg gtggcaccat tgaccaataa attggggaag cgagccggta agactaaggg
    18481 ttctctttca ttaccatcgt agttatcctg aaagtcaaca gtatttttat taatatcctt
    18541 taagagctct agcgcgattt tgctcatacg agcctcagta taacgctgag ccgcagcacc
    18601 gtcaccgtcc atagaaccaa agtttccatg accatcgaca agcatgtgac gatagctcca
    18661 ccactgggcc atacggacca tcgcttcata gatggacgaa tccccatgtg ggtggtactt
    18721 acccatgaca tcaccggtaa tacgagcaga ttttttatgt ggcttatcag gtgtgacgcc
    18781 tagctcattc atgccataaa ggatacgacg atgaacaggc tttaagccat ctcgtacatc
    18841 tggaagtgct cttgctacaa taacgctcat agcataatca atgaaactcg ttttcatctc
    18901 acttgtcaga ttgacgtcaa ctaaatgttt atcttgcatt taaggaatgc tccttttcta
    18961 gtcaatactc ttttaattat accataaaat ccttattttt tctgattgga aacgctgtcc
    19021 gaaaacaatt ttcataattt ggtcgaatat catgacaaag acattaaaat gtgttaaaat
    19081 aagatcgtat gagcaatttg ctctaactaa aatgaaggag atgtttagaa atgactgcaa
    19141 ctaaacaaca taaaaaagtc atcttggttg gcgatggtgc tgtaggctct tcttatgcct
    19201 ttgcactagt aacccaaaat attgcccaag agcttggtat tattgatatt tttaaagaaa
    19261 aaactcaagg agatgctgag gatttaagcc atgcgcttgc ctttacctcc cctaaaaaga
    19321 tctatgctgc tgattatgct gactgtcacg atgctgacct agttgtttta acagctggcg
    19381 ctcctcaaaa gccaggtgag actcgtcttg accttgttga gaaaaatcta cgtattaata
    19441 aagaagtggt tactcaaatt gtggcctcag gctttaaggg aattttcctt gttgctgcta
    19501 atccggtgga tattttgacc tattcaacct ggaaattctc aggtttccct aaggaacgcg
    19561 ttatcggttc tggaacatca cttgactcag cacgcttccg tcaggcactt gctgccaaaa
    19621 ttggtgtaga cgcacgttct gttcatgcct acatcatggg tgagcatgga gattcagaat
    19681 ttgctgtttg gtcacatgct aatgttgcag gggttggatt gtacgactgg cttcaagcta
    19741 atcgtgacgt tgatgaacaa ggcttggtag acctctttat ctctgtacgt gacgcagctt
    19801 actctatcat caataaaaag ggtgctacct tctatggtat tgcagtcgcc ctagcacgta
    19861 ttacaaaagc tatccttgat gatgaaaatg cagttcttcc actttctgtt ttccaagaag
    19921 gccaatacga aggcgttgag gattgctata tcggtcagcc tgctattgtt ggtgcctatg
    19981 gtattgttcg tccagtcaat atcccattga atgacgctga gcttcaaaaa atgcaagctt
    20041 cagcaaacca attgaagact attatcgacg aagccttctc taaagaagag tttgcgtctg
    20101 ctgctaaaaa ctaattaaaa aatgaatgtg ttagatcttg ctctaacgtt ttggaatcac
    20161 tacaaaaagc ctaatccaat cggataggct tttttcatgc gtctaacagc gaggtgcaag
    20221 acaaagcacg ctttcattaa gcatcgtgtg tgctatgctt atagtcttaa gtcacaaaaa
    20281 agacaaccag ctttatgagc tggctgctta ttagcttgtt attcagcacc aagtgctgcc
    20341 attgtaatgt agttatatgg cttgttaaag tgcggtaaga agaaaatatc agtcaaagct
    20401 aatttctcaa tggtcactcc ttcttggata gcaagtgaga acatatgaat tcccattgaa
    20461 atatcttcat gtgaggccat ttgagcacct agaatacgac gtgattcttt atcgtagaca
    20521 atcttaatgg ttacttggaa gttaccatgc tcgataaatt ctggtttttg attgtcagtg
    20581 tattctgtta ctgctgcatc aaagccaagg cattttgctt tctcaagagt taagccagtt
    20641 gataccatgt gcaagccgta gatagagata ccatttgatc cctgcacacc aataccctca
    20701 agagctgtgc cacaagcgtt atgagctgcg acaatccctg tacgaacagc atttgaagca
    20761 agggcaatat aattggtatc gcgagttgcg ttgtcataga tggttgcaca atcaccgatt
    20821 gcataaatcc ctggaataga tgtttcttgg tgtttgttaa caaggaaggc accattacgg
    20881 aaaagctcaa tcttgccagc accaagagct gtatttggac ggaagccaac tgcaaggata
    20941 accatatcaa caccatattc attcttatca gtgattagct tttcaacctt gccatcacca
    21001 gcaacctctt tgacagtttc cccaaaggcc aactgaatac catgctcttc taggttttta
    21061 gacatgacat ctgtcaaatc acgatcatag tagcctgcta gacaagtatc cgcaacatca
    21121 atcagaataa cctctttgcc cttacgttgg aaggcttctg caagctctac accaatgtag
    21181 cctgcaccaa cgactgcaac gcgcttaatg tctttgtttt ctaatttcga aatgacatct
    21241 gctgaatttt ggtacaattt aacgaattga agattttcaa gtgttgcttc aaactctaat
    21301 gagccctctt tgatttctgc acctttaatt ggtggcaaga taggctgtga accagttgca
    21361 aaaattaatt tgtcatatga ctcaacatgc tctttgccat caacaagggc tgtcactgtt
    21421 ttagcatcgt agtcaataga ttgaactggt gattccatgt aaaccttagc accaagggac
    21481 tctagctctt ccttatttga gtagaataag ccctctgggc cagaaatttg ttcgccaatc
    21541 caaagtgcca taccacagcc taagaatgaa atatttgagt tttggtcaaa tacaacaatc
    21601 tcattagcat caccatagtt tgttaacata gtcttgatac atgccgtacc tgcgtggttt
    21661 gcaccgataa caacgatttt actcatatga ttatgttcct catttcacaa tttatattag
    21721 gtctctatta taacacaggg aaaaagcgct tccaactaaa atgctcattt ttcttgcttt
    21781 tttataccgt tttttagtca ataaataaga cagcctatca tttgttgaag ggtcgtacaa
    21841 agaccggttt gcttcagtta agtcaagacg acattcttat tcaactattt tcccaaattc
    21901 attacatgat taagaccatt ttttgtcgtt aacttctaaa aaagactcat aagctcaatc
    21961 aggtaaagat tgacatgtac ctcttgagca taataaatat tgccgccgtt gcaataaagc
    22021 tttccaccag agaggagggc taaggggtgg taataaaaat aggtttttcc agtagtattt
    22081 cctaggctgg gtgcaacgac agttctagaa tagttagtgg ctagttcaat tgtatgctga
    22141 ccgccatttt tagcaacgta atcaatatag gcggttccaa aattgtaagc ttgaacagct
    22201 gtccaagggt ctacgccggc tttttctgct aaagctaaat tgtgagatag caatctgaca
    22261 ccatactcaa tgctagattg actatcggtg atcgaatccc ttatgccaga gctgctttcg
    22321 cttgactgca taacgtcagc ttctcctccc ttagtttccg tgtatatcat ggctagtacc
    22381 agatcgacgt ctgctttgtt accgttttct gctaaaatac gctctactgt tggcttgtat
    22441 tgtaggactc tgtgcacatt cttatgaatg gtaactgctt cgtacaggca aaaaatgagg
    22501 acggctaatc ctaagatacg ctttaacact ctaaacattt agttattttt gatatcctct
    22561 atatttttta tcaatatgga ataggttccg ttgtcattca agataaactc tactgactca
    22621 gcatcttgat aaactgcatt agggacaaga agctcaattc catttgacag cgacagcttt
    22681 tgcgtctcta gcttttttag ctgtctagaa tgatcaatat cactgacctg aattggttcg
    22741 ggaatcattt ccttgacctg atccacaaag gttaaccttg cagtcaggtt ctggtcaaat
    22801 aattgatctg ctagcttttc tggagataga gctgtttctt cttctagatt tttagccagt
    22861 gctactttca tctttgattg aaaagcaaag tcatcttggt taaaattctc ggcaaccttt
    22921 tgagcggtct gctcaagcat ttgaatagat tttttgacag attgctcagg tgttaccttt
    22981 agcagcttct cagaaaagta atgagcaaag cttccattgt gcttcatgcg tttttcgatt
    23041 aagtagtaat agcctgtttg acggttaatg accaaggctt catcaggtgc ctgagtaggg
    23101 cttggcaaat tattttgcgt gatcgtaata ggattttcat gatcgtctga tagatgggca
    23161 aaatgctctt ttagggcaat gcgtaaaaag gccagataag gcactccttc cttatcaaac
    23221 tgaataaaaa ccaaatcgtt tgtcttttga tgttcagaag cgacaaattc ttccttccaa
    23281 agcttggcaa ttgttactga tgtttccaaa agctctgtac cgattgtggt aaaaaaagca
    23341 tgatcagctt ctaattgccc acgtttagcg tcgtcagaaa aaaccttggc taattttttg
    23401 cgaaaatact catcaattct tggtgttata gctactaaag catctgataa gatcagctcg
    23461 gtatcgtttg gtgtgaattg gtggatcaca attcctttta tataaatatc tagcattgtt
    23521 agttcttctt gtataatggg aaggcgtcag tcaatcggcg aacctcataa cggacctctt
    23581 caaggatttc aggctgctgg tggttaacca aggccttgat aattaaatga gcaatagtcc
    23641 tactttcgtc tactcccatt ccacgactgg taatggcagc gcagcctatg cgaatgcctg
    23701 atgttttaaa gggagatagg gtctcaaaag gaatagcatt tttgttaagg gtaatattaa
    23761 cctcatcaag caaggcttga gcaagcttgc cattttcaat caccttagtc acatcaacaa
    23821 ggaaaagatg gttatctgta ccgcctgaga tcagacgaaa acgatcatcc ttggcaaaaa
    23881 cctctgccat tgctgctgta tttgctataa cagcccttgc atagtctgta aaggcaggat
    23941 caagcgcctc cttaaacgca acagccttcg ctgctatgac atgctccaaa ggcccaccct
    24001 gtagaccagg gaaaatagct gcattcattt tccttgaaat tgcttcatca tttgtcaaaa
    24061 gcaggccacc acgaggacca cgaagggttt tatgagtggt tgaggtcaca atatgagcat
    24121 aaggtactgg attttgatgc agacctgctg caaccaagcc tgcaatgtgt gccatatcca
    24181 ccatcaaata ggatcccacc tggtctgcaa taaaacgaaa ttgctcaaaa tcaatctgcc
    24241 gagaataggc tgaggcacct gcaacaatca acttaggctg aacagcctta gcttgcttta
    24301 ggatagctgc gtagtccagc ttttcagttt ccttatcgac agtgtagccg acaaattgat
    24361 aggtttttcc agaaaaattg acaggtgagc catgtgtcaa gtgacctcca gctgccaaat
    24421 ccataccaag cacagtgtca ccagcattaa tcagtgccat ataagcagca gcattggcct
    24481 gactaccaga atgaggctga acgttggcat aggctgcacc aaagagcttt ttggcacgct
    24541 caatagcaag gctttcaaca atatcaacat actctgtgcc gccataataa cgcttgcttg
    24601 gatagccctc agcgtatttg ttggtcaaga cagagccttg tgcttgcata acagcctttg
    24661 agaccatatt ttcagaagca attagctcaa tattatgctc ttgcctgtcc tcctcggcct
    24721 gaatagcctc ccaaagctcc tgatcatagt ctttgtagtt ctcgttgtta aacatcatta
    24781 ttgtctcctc tataatagct tcataaatcg taattgtgtc ttatcatcta catagctcag
    24841 cttacggtaa aaggcatgtg cctcggtcct gtgactagca gaattaagcc gaataaagct
    24901 tactttctcc tgcttagcct tctcctctaa agcagctagt aagcgacgac cgatacctct
    24961 accttgatgg tccagcctca ctgctaaggc caaaatatta aagccttttt ccgagtaaag
    25021 cgactcgtag cattcagcat gcagatagcc taagagcaga ttggtcttag tatcagcata
    25081 gcccagcaaa taatgatgct tatcggatct tagtttttcc aattggcttt ttgtcaattc
    25141 aagagaaacc ttgtacccca aggattgatc attaatgtca caaatagctt gacaatctgt
    25201 ttgatctagt ggtcttagca tagccttacc tcctctaaaa tggcagctct ggaaccttag
    25261 ctaataattg ctccttagta atagcacctt gtcgtaaaat actgacctta ggtgacgata
    25321 aatccaaaat agtagaatcc ttccctgtca aataggcatc atcagcataa ccatcaacct
    25381 ttccatcaaa tgccttgaca atgtcattaa agcattttcc actctttgag cctgacaggt
    25441 tagcagatgg cccaatcaag ggacccgttg ctctgataat tttagctgtg agagggtgac
    25501 tgggtagtcg aaagccaact gtttttagcc cagaattaat ccaatagggt gtctgggcat
    25561 tggcttttag gataatcgta agtggaccag gtaaaaaagc ctcgtacagc ttgttaagat
    25621 aggcaggctg ctgcttagaa aaagccaaaa tactctcaaa atcagccaca ttaaggttca
    25681 tagccttgtc gcgaggcctt tttttgagac gataaacagc attaacagcc tcttcattta
    25741 aggcctgagc aaaaagacca taaactgtct cagttggtaa aataagagct ccaccagcct
    25801 taattgtctc tatcaaatgt gttatcatca acaaccacca ttctttcttt acccagcata
    25861 tccttaagca ctctgatacg cttttgaggg aaacgcttgg ataagagcct ttttaagcct
    25921 tctccctgct tgtagcctat ttcaaaatag agcttaccac ttgtcgtcag ataagcacta
    25981 gcttgttcga taatgcgtcg gtaaatagaa aagccatttt ctgcagcaaa taaggccaaa
    26041 tgcggctcag attgataaac attcaagcca acctcgtcct tatcctcata ggcaatatag
    26101 ggagggttag aaacaatgat gtcaaactgc cctgatagct tgctaaaaag gtctgactgc
    26161 tcaaaggcta tctctacatg atgatctaaa gcgtttgagt aagcaaggct caaggcatca
    26221 gctgaaatat cagaggctgt gacctgccag ttaggtcttg ctttttttaa agcaattgca
    26281 atagcaccac tgcctgttcc aatgtctaaa acggatttgc gagtagcgtc attttccttc
    26341 aagataagct caactaattc ttccgtctct ggtcttggga ttagcacgcg cgaatccact
    26401 gcaagcacca gatctctaaa ataagccctg cctgtgatat attgtggcga tacatgctgg
    26461 ctaagcgcta aaaaaatccg ctctaataag gcttgatcct ctgaagtgac ctcttgattt
    26521 tgatgaagca aaaagtcaag gcttgtccac tgctttaatt ctttaaaaac ataggcgagg
    26581 ttttcacgat cctcacctat gttttctagc ctgtcttcgt aggctcttag ttgcttagca
    26641 tagttcattg gttatttagc gattctaatt tctgagtttg atcatatagc actaaagcgt
    26701 caacaatctc gtctaacttt ccagacaaaa tggtgtctaa tttttgcagg gttagaccga
    26761 tacggtgatc tgtcacacga ttttgtggga aattataggt ccgaatccgt tcagaacgat
    26821 cacccgtacc gatagttgat ttacgctctg cgtcctgctc gtcctgtgcg atctgtgcaa
    26881 aatgatctgc tacacgtgcc cgaataatct tcatagcctt gtcacgattc ttttgctgcg
    26941 ttctttcctc ttgcatctca accttgatgt ttgttgggag atggacgata cgaacagcgg
    27001 ttgccacctt gttgacattt tgtccgccag caccagaagc atggtaaata tcaatacgaa
    27061 ggtcctttgg atcaatgtcg tactcaactt cttctacctc tggcatgact aagacagtcg
    27121 cagttgaagt atgcacgcgc ccttggcttt ctgttacagg aacacgctgt acgcgatgag
    27181 cacctgattc gtattttagc ttggaataaa cagattgtcc tgaaaccata gcaacaacct
    27241 ctttaatccc tccaacacca ttataggaag cctccattac ctcaaagcgc cagccttggc
    27301 tttcggcaaa tttttggtac atggctaaga gatcaccggc aaatagagca gcctcatcac
    27361 cacctgcggc accacgaatt tccaagataa tatttttatc atcatttgga tctttgggaa
    27421 gcagcaaaag ctttaacttg tcctcatagg cttccttggc agacttggcc tcttttagct
    27481 cctccttggc catctcttca atgtcaggat cgccgccggc ttccttaatc atctcctcag
    27541 cgtcatcaat ggattggata atagccttat actgacgata agctgctact gtttctcgtg
    27601 tgctagcctc ttcctttgac agagccataa aacgtttggt gtcagaaaca acctccggat
    27661 cacttaataa ttcgcctaat tcttcataac ggtcctcaac agcctgtaat tgatcataaa
    27721 tattcattag ggggtattct ctcctctttt tacttgtttt agttgttatt agattggtgg
    27781 gtgaaaataa tgcttgcgac aaactggaat ataggtctca ttgccaccaa tttgaatctg
    27841 tgctccctca taaacgggct taccatgttc tgttcgcaat accatagttg cttttttgct
    27901 gcaatattga cagatggttt ttatctcatc aatcttatca gctaacagta acaggtattt
    27961 ggagccttca aacaattcat tttgaaaatc attttttaag ccaaaggcca tcactggaac
    28021 atttagctca tcaaccacac gtgctaaatc atagacattt tgcttgctta aaaattgaca
    28081 ttcgtcaatc aagacgcaat agggcttctc ctgcaattca gcaataaatg caaaaatatc
    28141 catatcattc gaaattggta cagcctcacg acgcatgcca atccgactag aaacaatgcc
    28201 aaagccatca cgtgtgtcta gcgcacttgt cataatcaca acaggcttcc cctgttcttc
    28261 ataattgtgt gctaccttca agatttcaat ggtctttcct gaattcattg ttccatattt
    28321 gtaatataat tgagccaaaa tggagattcc taccttcttc ttttgtccta cttattctat
    28381 catatttgtc cctatttggc gattgcctta tctgaaaatc ttattttcac aacagctaaa
    28441 tcctgtgctg ttgagctaag gttaggcttt ttgaagctga catgctacaa tagaggtatc
    28501 attaaaaaaa ggagattgac tattatgcca tttgtaacga ttgacctgtt tgaggggcgt
    28561 agccaagaac aaaaaattgc cctagcgcgt gaggtgacag aggttgtttc tcgtatcgca
    28621 caggctccaa aagaagcgat tcatgttgta atcaatgaca tgcctgaggg gacctatttc
    28681 ccgcatggtg agatgaaaac caaagcctaa tgcctaagtc ccacttatct aggtgggctt
    28741 ttcctatttg aaaaggaggg cctgatgata gctactgatc agatcaagat gatgggaaca
    28801 atcattgata tttgcattga ctcatcaaaa gcaaagcagc aagcagctac tatccgagag
    28861 ctactaaccc tttacaatca ccgtttttcg gccagtgacg acagctctga attaatggca
    28921 atcaaccata tggcaggtat tcagccagtg cgtgtgcatt cagatttgtt tgacttaatc
    28981 tcaatcggaa aagagcatag cttggcttat ccaagcaacc ttaatatcac acttggtcct
    29041 ttagtgcaaa gctggcgcat cggcttttca gacgctaagc ttccagatga agcaactatt
    29101 gatcgcagac taagactaac caatcctaat catatcatc
//
LOCUS       DARYLJ010000032        28348 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYLJ010000032 DARYLJ010000000
VERSION     DARYLJ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28348
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(28..738)
                     /gene="speh"
                     /locus_tag="TU746_001258"
     CDS             complement(28..738)
                     /gene="speh"
                     /locus_tag="TU746_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeH"
                     /protein_id="HEL0891604.1"
                     /translation="MRYNCRYSHIDKKIYSMIICLSFLLYSNVVQANSYNTTNRHNLE
                     SLYKHDSNLIEADSIKNSPDIVTSHMLKYSVKDKNLSVFFEKDWISQEFKDKEVDIYA
                     LSAQEACECPGKRYEAFGGITLTNSEKKEIKVPINVWDKSKQHPPMFITVNKPKVTAQ
                     EVDIKVRKLLIKKYDIYNNREQKYSKGTVTLDLNSGKDIVFDLYYFGNGDFNSMLKIY
                     SNNERIDSTQFHVDVSIS"
     gene            complement(764..1441)
                     /gene="spei"
                     /locus_tag="TU746_001259"
     CDS             complement(764..1441)
                     /gene="spei"
                     /locus_tag="TU746_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL0891605.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKAKFFSGKRVDIFTLEYSPPCNSNIKKNSYGGITLSDGNRIDKKN
                     IPVNIFIDGVQQKYSYTDISTVSTDKKEVTIQELDVKSRYYLQKHFNIYGYGDVKDFG
                     RSSRFQSGFEEGNIIFHLNSGERISYNLFDTGHGDRESMLKKYSDNKTAYSDQLHIDI
                     YLVKFNK"
     gene            complement(1715..3049)
                     /locus_tag="TU746_001260"
     CDS             complement(1715..3049)
                     /locus_tag="TU746_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL0891606.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            complement(3166..3393)
                     /locus_tag="TU746_001261"
     CDS             complement(3166..3393)
                     /locus_tag="TU746_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL0891607.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            complement(3390..3662)
                     /locus_tag="TU746_001262"
     CDS             complement(3390..3662)
                     /locus_tag="TU746_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891608.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            complement(3674..4285)
                     /locus_tag="TU746_001263"
     CDS             complement(3674..4285)
                     /locus_tag="TU746_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL0891609.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            complement(4282..4719)
                     /locus_tag="TU746_001264"
     CDS             complement(4282..4719)
                     /locus_tag="TU746_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL0891610.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            complement(4731..6617)
                     /locus_tag="TU746_001265"
     CDS             complement(4731..6617)
                     /locus_tag="TU746_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL0891611.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            complement(6632..7750)
                     /locus_tag="TU746_001266"
     CDS             complement(6632..7750)
                     /locus_tag="TU746_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL0891612.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            complement(7750..9732)
                     /locus_tag="TU746_001267"
     CDS             complement(7750..9732)
                     /locus_tag="TU746_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0891613.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGEPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANN
                     KGVKLVLTPTKAKMEPETFTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRN
                     MALGMSYRDVVDGNNADLILDWAENPDIIFDGNGGI"
     gene            complement(9742..10584)
                     /locus_tag="TU746_001268"
     CDS             complement(9742..10584)
                     /locus_tag="TU746_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0891614.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            complement(10596..14978)
                     /locus_tag="TU746_001269"
     CDS             complement(10596..14978)
                     /locus_tag="TU746_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL0891615.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNTFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVGIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGQQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSVLSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWA
                     VMNPASAISTIMPLLSLFGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IEQLLNTAVTKGPGIIQGLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQ
                     LITSLVQGIGQNATNLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIDSFGNSLQANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAG
                     IQLVAQLAVALIKGLPQIISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATVMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFD"
     gene            complement(14993..15226)
                     /locus_tag="TU746_001270"
     CDS             complement(14993..15226)
                     /locus_tag="TU746_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891616.1"
                     /translation="MEGLEYKQLAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            complement(15301..15756)
                     /locus_tag="TU746_001271"
     CDS             complement(15301..15756)
                     /locus_tag="TU746_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891617.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDMDATQIQIIEDMIGRMSNAVS"
     gene            complement(15810..16409)
                     /locus_tag="TU746_001272"
     CDS             complement(15810..16409)
                     /locus_tag="TU746_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL0891618.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESTGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            complement(16421..16780)
                     /locus_tag="TU746_001273"
     CDS             complement(16421..16780)
                     /locus_tag="TU746_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891619.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            complement(16784..17128)
                     /locus_tag="TU746_001274"
     CDS             complement(16784..17128)
                     /locus_tag="TU746_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0891620.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            complement(17125..17403)
                     /locus_tag="TU746_001275"
     CDS             complement(17125..17403)
                     /locus_tag="TU746_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891621.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            complement(17414..17770)
                     /locus_tag="TU746_001276"
     CDS             complement(17414..17770)
                     /locus_tag="TU746_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0891622.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            complement(17782..18669)
                     /locus_tag="TU746_001277"
     CDS             complement(17782..18669)
                     /locus_tag="TU746_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL0891623.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            complement(18682..19251)
                     /locus_tag="TU746_001278"
     CDS             complement(18682..19251)
                     /locus_tag="TU746_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL0891624.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            complement(19428..19685)
                     /locus_tag="TU746_001279"
     CDS             complement(19428..19685)
                     /locus_tag="TU746_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891625.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRK"
     gene            complement(19690..19878)
                     /locus_tag="TU746_001280"
     CDS             complement(19690..19878)
                     /locus_tag="TU746_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891626.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            complement(19906..21354)
                     /locus_tag="TU746_001281"
     CDS             complement(19906..21354)
                     /locus_tag="TU746_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL0891627.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            complement(21314..22846)
                     /locus_tag="TU746_001282"
     CDS             complement(21314..22846)
                     /locus_tag="TU746_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0891628.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEKIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKAYTSDTIYTYEDYN
                     LETKGMRLKDYEGHFFRGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            complement(22862..24139)
                     /locus_tag="TU746_001283"
     CDS             complement(22862..24139)
                     /locus_tag="TU746_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL0891629.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGAEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAN
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLPSFFGLDYGFINDPSALLHV
                     KIDDANKKLYILEEYVRKNLTNDEIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYTNEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            complement(24129..24581)
                     /locus_tag="TU746_001284"
     CDS             complement(24129..24581)
                     /locus_tag="TU746_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL0891630.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            complement(24671..25087)
                     /locus_tag="TU746_001285"
     CDS             complement(24671..25087)
                     /locus_tag="TU746_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL0891631.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            complement(25084..25800)
                     /locus_tag="TU746_001286"
     CDS             complement(25084..25800)
                     /locus_tag="TU746_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL0891632.1"
                     /translation="MNIKEAKIGDKVWVEGIINSSFSNGGVHVNHAGVDAFYDLERTK
                     IKPDGYAGQSPKYLKNIIAKMRELPEHDRAVWIKGIFKEFGIENDISYYLGHKQGVLQ
                     AKDSLKPEVLQYVADWYEKHKDNLEYYIWEYIAEWDNQEKDDFFVFMNFSAFKPIQTL
                     VNMHQFGYTIKKEKLYTVEIPNPNAKQIALRLEKWVEGKVRIVATYSSNNFTDYMRLT
                     EREIRKDFDWAWQFAEEVTG"
     gene            complement(25797..26090)
                     /locus_tag="TU746_001287"
     CDS             complement(25797..26090)
                     /locus_tag="TU746_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891633.1"
                     /translation="MNTNEKVIDTICHIRHCGDRYDMCQDMRSWVAERNGLIQDLLKA
                     KKQIDRNRIAKRLDRAQKNISDIITKVTGDLWQGSDQVIAEQCFLKVLEEMQK"
     gene            complement(26087..26272)
                     /locus_tag="TU746_001288"
     CDS             complement(26087..26272)
                     /locus_tag="TU746_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891634.1"
                     /translation="MAENKTGMMTLPIDYANRALAKEEILDELVEREIVDVDLLIELA
                     EDNPFWMSALNFNRGTK"
     gene            complement(26297..26524)
                     /locus_tag="TU746_001289"
     CDS             complement(26297..26524)
                     /locus_tag="TU746_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891635.1"
                     /translation="MNKQKFEKLDKVKELLDELKMSEFMAPLLVGDQIMEIINDLHND
                     PGQFGAQVFLPSPDKKYKFVVRICREENLED"
     gene            complement(26505..26693)
                     /locus_tag="TU746_001290"
     CDS             complement(26505..26693)
                     /locus_tag="TU746_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891636.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAT
                     VKEKYTREREMKNEQTKI"
     gene            complement(26694..28016)
                     /locus_tag="TU746_001291"
     CDS             complement(26694..28016)
                     /locus_tag="TU746_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL0891637.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWSTEIGKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGARLETSQTRFKDKYFVPDKRNGLIIYSWALRDGAEAEIYNKIE
                     DICISMKAKDYLKLPPRTDNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLAN
                     KLLQMANGAIYDDDKTTVAIHDDKLDALENVVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            complement(28013..28288)
                     /locus_tag="TU746_001292"
     CDS             complement(28013..28288)
                     /locus_tag="TU746_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL0891638.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFASPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDIALKEMENWV"
BASE COUNT         7666 a         6254 c         4864 g         9564 t
ORIGIN      
        1 ttaataaaca gcttcttaaa aatataatta gctgattgac acatctacat gaaattgagt
       61 tgagtctatt ctctcgttat tggaatatat ttttagcatg ctattaaagt ctccattgcc
      121 aaaataatac aaatcaaaaa caatatcttt acctgaattt aaatctaagg taacagttcc
      181 tttagagtat ttttgttccc ggttattata gatatcgtat ttcttaatca ataactttct
      241 aacttttata tccacttcct gagcggttac tttcggttta ttgactgtaa taaacatagg
      301 cggatgttgt ttacttttat cccacacgtt tataggaact ttaatttctt ttttttctga
      361 attagttaat gtaattccac caaacgcttc ataccttttt cctggacatt cacaagcctc
      421 ttgtgcagat agagcataaa tatctacttc tttatctttg aattcctgtg atatccaatc
      481 tttctcaaaa aaaactgaca aatttttatc cttgacacta tatttcaaca tatggcttgt
      541 tacaatatct ggagaatttt ttatactatc ggcttcaatt aagttagaat catgcttata
      601 aagcgattct agattatgtc tattggttgt attataagaa tttgcttgaa caacattgga
      661 atataaaaga aatgacaaac atataatcat gctgtagatt ttcttatcaa tatgtgagta
      721 gcgacaatta tatctcattt tttctcctta agaagtgaga gttttattta ttaaatttaa
      781 ctaagtatat atcaatatga agttgatcag aataagcggt cttattatca ctgtattttt
      841 ttagcatact ctctctgtca ccatgtcctg tatcaaaaag attataagaa attctctctc
      901 cactattcaa atgaaaaata atatttcctt cctcaaagcc agattgaaat ctagaggagc
      961 ggccaaaatc tttaacatca ccgtatccgt atatattaaa atgtttttga agataatatc
     1021 ttgatttcac atcaagttcc tgaatagtaa cctctttctt atcagtactc actgtactta
     1081 tatctgtata gctatatttt tgttgaacgc cgtctatgaa aatattaaca ggtatatttt
     1141 ttttatcaat tctattaccg tcgcttaaag taatacctcc atatgaattc ttttttatat
     1201 tagagttaca gggaggagaa tactccaaag taaatatatc caccctttta ccagaaaaaa
     1261 atttagcttt ttctacgcta ttaagttcta cttttaattc aatcgaacta ttgccataag
     1321 gaatattttt gtagaacaaa ctacctgaaa atggcggacc ttcatttatt tttcctttta
     1381 cttctgttgg atcatatgta gagtataaat tccttaaatt aataactccc acactactca
     1441 tctcatacgc gtaacacgtt ggaattatag ctgatataaa tacccacaat agaaaagatg
     1501 aagttaaaaa ctttttaaaa ttaacattta caatttttct cacttataag tgtaccctat
     1561 tcttctttaa taataagaaa tcacaaaata ttttagcaca aaaaagaaaa aaatcaacga
     1621 aaatgcttaa ataacaatta aaatctttat aacaaaaaca gcccccgcaa aagcgagggc
     1681 atttgtctta tctaaaggag ctttacctcc tattttatac ttgtgttgca ttagataaat
     1741 acttatcttc gacccactgg tcagactgag aagcgttaat acgtgaccat ccattcactt
     1801 tttcatagac tcttacacga gttcctgcct tgataaattc tttatcagcg ctacttgcgt
     1861 ttggcttaga ctctacataa tagtctgtgc taagggttgc ttcgtagtaa ggtacattcg
     1921 agttgtctaa tttagtgtta gtatctagct tttgattaaa agtaagctgg ctttgtggtt
     1981 tgtcaatctt aggtatatcc actttgctac tatcatctgc taataataca atatttttat
     2041 ctaaaccacc tgctactcct acacttgtga actgccacca gcgcacacca tccattgaag
     2101 ggaagaactc ccaaagtggc tctgttcgta cttcgtagtc tggataacca gctatccaaa
     2161 tgctgtttgg gtacttagcg ataatttgct gataatcaat attattaagc gtaaatggtt
     2221 tatagctgta ataaacaggc ttatatccag cgtttgcaat tttatccata aacgcaataa
     2281 ctgcattagt gttagcttct ttgtcggcac ttgcagagtc ttcataatca atgactaagt
     2341 aagagacttt tttggttggt aaattggaca gaaataaatc tgcttctcgt tgcgctaagt
     2401 tgctatctcc tccaaatcgt ccaaagtgat aataaccaat agggtcacta gtattagctt
     2461 gttgctgatg cctatcagac agccaagcga gtgactcgga tactttgata atcgttttag
     2521 tagtgccagc ttgctgacaa gtagcggtta agtctgcttg ttgataagct gatacatcaa
     2581 taaaataatc gcctttattt agtcctatat tacctataac agtaactgca tttttaaaaa
     2641 cttttggtct aaatgcagta ggataagtcg ttgaatatgg tatttttact aaattatatg
     2701 ctccgtttgc tccaccctgg ttttgaccta aaaaccatcc gtatccacta cctgcatcac
     2761 tatcaaaaat agccacatgg ctatacggtg taacacctgc aactaccata aaaattgcga
     2821 catctccagc ttgcatagtc tctacttcgt caaagtagtt taaaatacca tttttgtgac
     2881 gttgttccca tatatccctt gcatatcctg tatttgtaca gtttgcgtat ggcagtccta
     2941 gatacttaca gtagtctgcg tagccatccc aacattgcgc accaagcgat ccatcaatat
     3001 cgtaagcatt gccatttgaa cgacttttat attcctgata tgtagccatt tatccctcct
     3061 tatctaaaaa tgggcttaaa atcaaagcaa caacagataa tggcacatac agtattgcta
     3121 ttgctataac taatgctaat cgtgtgattg cccgcatgtc ccctcctatt gttttggttc
     3181 gtggtaagtc aaagcttgct cactgtctga caggcctttc gtggttggat ctgtgacaac
     3241 accgagcaat accaaaagcg ttacagctgt gtttgcaata tccgcgatgt ttgatggtag
     3301 tttaatacct aattgctgtg ccagtaaaaa gatagctcct aaaatagcca tcaaggttac
     3361 tttgttttgt agtcgtaatt ttaaattgat catgcttcac ctctcataat atctttaagt
     3421 tctcttacct cacgattgag gtttttaatt tgctctgtca ttgtgatgag cgttttgttt
     3481 tgctcatcat gctcctcaag acgccgagca ttttggcgtg taacaatttt taaatgctct
     3541 acttcagact gcaacaaagt aatatctgtc gcatgcttga tggattttgc attaaaaata
     3601 ttgtaagtcg tgacgatagc taaaataaag ccaccaagac caaatatcaa ctctgttgcc
     3661 atagcttacc tcgctaatcc tgcttaacta agtccgcata cttaatgact gtgactttat
     3721 cctcttcctc tagctcttta agcgtctgtt tgtcataagt aaacggctcg ttaacgtgta
     3781 caaagacaag attaccttct cccgcttgat cttcgtgcga ctcatctaca acagtaaaca
     3841 cgtcataagc ctgatactcg ccttgtttag caggttcaat aagctctaac atacctttgt
     3901 agatatcggg ttcaactttc ccaccacttg tcaatacgtg gatggtttgc aagttaatca
     3961 tccgctgtgt acgctctgcg gacaccttag ctaatcctgc ggctgtttgg gctgttttag
     4021 cggtcttagc ggtttcctgt gagatttttt caaggtcgtc tactttttgc acggcttcgc
     4081 ccatagcgat ttcgacgtat tcagattttt taaattcttc caaagtagct ttgataatct
     4141 ctgtgtcatt agttgaagtt aagccctgct tgattggttg agagatgact gagccatcct
     4201 cagcagtgat aataatatgt gtgcttgcga ctgctcctgt gctgtcaaat tgtgggtatt
     4261 ttcctgtcac tttccaattt ctcatggttt ttctcctttt ttactttctt caaattgttc
     4321 caaaatgttg tcgataagaa tgatttcaga tgatgtaaat tcatcttcac actcttctaa
     4381 aaagtttaaa aagtcaataa atcgcttgga gtactcaccc cctttaatca caatttcttc
     4441 atcagctagc tcgttgagta ggccgttgaa ctcgtcgagt ttagcggggt ctgctagctt
     4501 gatgtttttg tgctcatcaa tgacaaactt gccatctttg tctttttgag catacagatc
     4561 aataaggtca ccctcatcct tggcgtactc tttgaattta tcgactactt ttgcgagtag
     4621 cttagcacgt ccgcggtttg ctcgcatgtt cgtgactttg attttgtcta gtacactata
     4681 tagtgtgttt aaatctttgt ttttaagcgt taaatccatt gtttctccta ttaaattttg
     4741 ttgatatgat tatttaactc gttagtgacc gcacttgtaa aattgctatg agcagtattc
     4801 cagccgacgt tagccaagtg cccccaacag cggcctaagg ctactacagc cgcatacaag
     4861 tcgttcatgt caagcatttt ttgcatcttg tctggtctaa atttaaatcc tcgattgatg
     4921 ctaaagtcat ctgcaatcaa gacattatca ccgtatagct cggtttggtc gactgcagca
     4981 gtatgattat atcccgtagc gtacctaaat gaccttagcc ctgcaaaacg accggaagaa
     5041 gccgagttaa caccgtcacc agatgaggtt atcccgatcg atgcatacaa cgctgaccct
     5101 gtataacctt tgggcgtcgc attactaaaa tgtacaaagg cagtatgtgt gccatcttta
     5161 cgtactaagg cattgttttt gctattaaaa ttaattgtgg catcgctatt aaagtccatc
     5221 ttagctgtat ttaagtcgat aagcatcgct ccattacgag ccttaatgac cttaccctcg
     5281 agcaaatcag tgatagcata gccaatttta gctttgataa agttagcgtc taaaccaacg
     5341 atactacttg cgttaaggtt aatcactcta atcctagcag cgtcaatcgt gcctgcaata
     5401 atctgatcag ccctaatctt gatagcctct gctatctttg tggtaaaggt gccgttgaca
     5461 gtcgtattgc catcgagagc gatgtgttta cctgcgattg ttactccgta ggagttgagg
     5521 ttaattgctg agataatctc attaccagac attttggcat taatgccgcc agccttttgg
     5581 atagctaatt taatgctgtc tccagcgcca ctaataatac tcatgacacc atctctagta
     5641 acccgctgct caatttgtcc tgctagttga gtaaggcgcg attggatttt accagtcgga
     5701 gatccaacgt cgctctgtag ccctctaacc gtatgggtca agctactata gttttcttct
     5761 gcgtcctgca tccgcctttg gtaactctcc aaactctgct gcacacgact gacagcacct
     5821 tcacggtctc taatctcttg agagatttgg ctagctgttg actgctgtac cgctcttagc
     5881 ccgctaattt gtgactcgag ctctgtcctc gtgccttgat ttgagcgagt aaactcagca
     5941 cgtaagcccg caagcttact ctcgtaggcc tctgtagtgc cgcttgaggt tgttgtgatc
     6001 ttagccgata gcttgcgcaa ctcatcatca tacttttgcg atagcccttg tgctgaggct
     6061 ttaatctcag cttgtaaacc gattttatca ttggccattg tggcttttag cccctcgatg
     6121 cctgcctgat agcttgcgga tagcttccta tcagcatctc gatactcacg cctgatacca
     6181 tcaatggtgt cattgatgag cgctagcttt ttatcagtat cctcgctgat acgtgtagcg
     6241 acacctctgg cggagttgac tatctcggtc ttgatcttac cgtcgtagta ttcctgcaac
     6301 ataccacggt tagtcagctt gatttttgac caaagctggg aattagcagt atctgtcagc
     6361 tctaggctaa tctctttgag gtctttaaat agtccagtcg gattacctgt accctcaact
     6421 actactggcg caacatagct agtagcttgg tctcctcgct caatcatgag ctgattaaaa
     6481 tgcgctgtgc ctagacactt gctagctagt ctgacttttg ggttgtcgtc ctctgcggta
     6541 aatgtgtaat gcacacgtcc atccttacca ataacgaggt ttgactcgtc taaaataagt
     6601 gttgggtctc tgctcattta tcctccttaa tctatttttt tagtatgagt ttttttaact
     6661 cagaaattgc tttatctaca taagctttgg ttgccgcatg atcattcgct gtggggtcct
     6721 tgagtttcag gttgccatca atctgcgaag tttccttggc ataaaaacca ccgtcagact
     6781 tgacgtagaa cttatcatca ctaaggtttc taatcctaag caacttccct gtcgtgcctg
     6841 atgttgagtt aatgtagatt ccttgagcag cagtaccttt tccgcctttc tgttttttaa
     6901 cgatatcaat agataacgct gtagcgtttt catcgtattt tgcctcaacg tttgggtttt
     6961 cgtgtgtgat tttgagcgtt cctagcgctt tttctgaccc tcgtagctgc attgcactac
     7021 cattttcatt gtcgctagta atattaagcg ccgatgaaaa attgggggtg gttggctgac
     7081 gcatcacaat attaacggca tttgttgttc ccttataatc gacaaaaagc gctgatttat
     7141 tgaaggtctc tttacccgtc cgcaagctca ttaacggccc atcactggta tcattgttag
     7201 aatagacaac aacaccagca ccttccgatt tagacatatc aatgttaatc gctcctccta
     7261 cggaagatga gggtttaata ccacttttat taggtttaaa ctgtagttgt cctgtcacta
     7321 tgccgcctgt caaactcaat tttttgtcta gctctatttt tgactctgct tttgagtaaa
     7381 cagcgctttt atctgctttg cttgattcta atttggtgat tttactatta gtttcttttt
     7441 tttgtgcaaa cgcatctaga tttggtttat tttggagttg attataatct gtcgttccag
     7501 gcttgccagc agggccccga ggaccaattg ggccagttag gcctctttct cctgaaggac
     7561 cttgaggtcc catagggccg cgcaagtctt ttaagtcctt gaacttattt ttgccatcac
     7621 caacttttgg gtaacccgta gtcatatcaa ttccaatttc tcgctccatt aagatatcgg
     7681 agcttgattc ccactcttgt ttggtcatgc ctctatgctg tatccttgct gatgcaactt
     7741 cttttgacat taaatacctc cgtttccgtc aaaaataata tctgggtttt ccgcccagtc
     7801 caaaattaaa tcagcattat taccatcaac cacatctcta taactcatcc ccagagccat
     7861 atttcgcacc tccgacgcat ttaaatctac ttgcttagat ttgtaccagt caccacttaa
     7921 agtgactgag tagctcaaag gatagacgtt gatgacctct gtgtccttaa ttagagtaaa
     7981 agtctcaggc tccatttttg ccttagtagg tgtcagtacc agtttaactc ccttattatt
     8041 agcttggatc agcgtgatag ccactttttt gagcggctca catgtctgac taaagctgat
     8101 tgtgtaagtc tcgccacgct tgaaaccacc atcattagct tctacctcga taaaatcctc
     8161 atcaattttt ttaacacgat taggctcacc gaccagcaaa tttttgttgt agcgtgtctt
     8221 accgttgttc cctaaaattt cggcagttaa acgagattct tcgcttgtct cactcactct
     8281 atttttgagg tcatcaaagc tttgtttaat agacgggatg tcatcaactt ttatagcctc
     8341 tgtgattttt ttaatcgctt cctctggtaa cgctaggttt ttgagggcgg ctctaaattc
     8401 ttcaagctct ttatcggtgc gttggttgat ttcttcctgt gcttttttgg ctttttcgat
     8461 cgcctcagag atttgttttt cgaggtcttc acgccatcgt tctgggtcgt tcacaacctc
     8521 aggttcttcc cactcagcac cattccagaa atacattcta gtagtatcgc caacttttag
     8581 gaataatatg tctccttttt ttaaggttcc ttttggttca tctttgggca tttctgtgcc
     8641 accgtaaaca gtatttttcc cgtcagcaga tactagtgct tgtgttgcta cttcaattgc
     8701 agaagcaata tctgcatcta tctgattgat tctactgttt atagacagac ttcctacgct
     8761 ttgttttttc acagatccga tatcattaca agtgacttca tgttttacta aagctccagt
     8821 tgcgtcgtag tagcttgtaa aagaaactat ccgtatacgc tcttgaaaac ctaaagtctc
     8881 atttatcgcc ataatgtagt caccagcaac cggcctctca catctatacc cagctctcgt
     8941 taaatcttcc atatcaattt ttactgatat cttatatgaa ttttcaacat tactttttaa
     9001 agcttctttt agattatctg ccaccgtgaa gcgctcatcc gtcagaggcg ccccttcaag
     9061 tcgaccgtac tccttggcaa gaggactttc gtattccgcc tcaagtctcc ccttagagtg
     9121 gtcctctggg tcggtccatg caccaaagcc tttctgatag gtaataaagc tatcaatatt
     9181 cttttcaatg gtaaggtcat tcatgttgaa attttttcgt accactgttg acagatcagt
     9241 acctatgttt tttaatagcc gaacaacttt cccgctgact gaaaattcaa gtccggtcgc
     9301 tttaataatc tcattgaata aatctaacct ggacttataa ttaaaagatt gttttctaaa
     9361 tgcgttcaca cctacttcta gcttatagcg gtacccacta cctttaaata ctgtctctag
     9421 ataggtatca atggtatgag acccatctcc gagaccctca tagatactac tcttgctgaa
     9481 gtcccaaaaa aattggtgta tggcatcaaa cgaaacttgc gttttttgac caacatcaac
     9541 aggctttgcg taaataacaa cgtaatactc atcttcaaat ctaagtcgcc accctctatc
     9601 gatattattg aggacatcac tgtttgtata aatttccccg ctcactgagc gctcaccatt
     9661 aacagcatta gtatgcctaa tgacactaat gaccccatac tcaatgtcac gatgatccaa
     9721 aaaagtaatc attagacctc cctatttata caactctaca aaatttaaaa tcctaatcgt
     9781 gccaagaaaa tccgttttgt aagtaattct cttgttagga ttaggattga agataaaata
     9841 ctcatagttc gttttagcat tgacataatt tccgtttagt gtggtagcta tgcctgtcaa
     9901 aagtaattta tcactatttt gtagctggct attctgctta aactcaaagc gcctgccatc
     9961 aatttcaata taaaaattag tctgacctcc agaaggagta agctctataa taaaaggcca
    10021 ctctagctga cttgctttag cggttcctgc ataggcaaaa ctgccccctg atagagttat
    10081 gtcctttggc tttgtctcac cgaaaggtaa ttcagcagtt cttagcgcga aggaaagatt
    10141 atattttagt ccttgactgg tttttcctat aaattcataa gcgatagtgt cgtctaagat
    10201 gactttaaat ctatatttcc aaggtttatg aggagagcca ataagttgca ggtctcctgt
    10261 gctttcccct ggaagctcaa agttaaatag atctgagttt tcagggtaca tcttagtcac
    10321 gtagaaaggt tcgtcaacaa caagcagagc gtttagttcg tcctgtttgt ccaaaagtct
    10381 ttccacgttg cttaccgtca ctcttccttt gaccttaagc gttttagtcg taaaagtagc
    10441 cccatcgtag atgtaaccac tccttccttt gactgctcgg tgtgatacag atagtaaagg
    10501 agcgctatct tcaatagcaa tattataaat accaaagtca gacaacctag ttgcctgact
    10561 ctctttttct attaataaat ccaaaatact cccttctagt caaaaacaaa ataagaatct
    10621 ttagattgct ctcttgattc tttttcttta acagccgtgt aaattttatc tccaacaatc
    10681 tcattatgca cttcaaagat aggctctgac aattgagact gcctaacctc ttcgctaaga
    10741 ttatcaagag aggtattgat tccactatta ttaactttag cagatgttga aacagtacta
    10801 tttacccccc agttttgatc agtaactgct gttgcgtatg ctttacctag gctattgatc
    10861 tcacctatcc actctgccat accgagggca aacccctctc cagtaaatgc acctagtgtt
    10921 ttagtgacac gagatggtga gtgaatatct aaagcgcgtc taattgttgc tgctacatta
    10981 gcggcaatgc tgttagctat tgcgtagatt gtgcctgcgc tactagctag accattagca
    11041 aaaccttgac ctgcataagc tcctgcagaa gacatctgcc ctgccaaagc cctgaatatt
    11101 gagaggatct tctgacaagc attattagac accgcggttg cacgagacat cccagaagtc
    11161 actgaactta caaggtttgc catagattgc tttgcagtac tgttaatgct actaaatcct
    11221 gttttaaccg cattggctat cccattcatt gaggttgttg ctgaagtctt cgccttattg
    11281 aagccagact cgaccgccga ggacaaccta ttaacgcttg aggttgcaga ggttgctgca
    11341 gaagacattt cgcttgtcac actattagac agaccagagg ctgctttagt tgagtttgac
    11401 tgcattgatg ccaggctgtt actcacccct gagctcatag cttgcgcctg agaagttgca
    11461 cctgtgctag cagctcccat gttcgcacca acaccactag ctaagctgag cgtatgatta
    11521 atggcgtcta gattcattga agaagtcgca ccattaaccc ctgaagccat ttctcgagcc
    11581 tgagtagtag cgtttatatt agcgacagac atattagtgc taatgccact cgcaagagac
    11641 atcgaatcat tcaacccctg aagactcatc gttcctgtct gagcattaac gttattagcc
    11701 atctgtgtgg catttgatgt agcgtttata ttagcaagct ctgtattttg actaatgcta
    11761 ttaagcatag atgtcgtatc tgtattagct tgattagcca tagctgtcgt ttgcatccca
    11821 acattcatgg ccatgaccgt ggcgtccgca gagactttag ctgtacttgt ggaactctta
    11881 cctgtgattt ggtcccacat cgaactgaat ccgctcttaa taccttccca aactcctgaa
    11941 agagcgtttg ggatagcccc taacatggct ttaccgagcc ccataattaa ttgaataccc
    12001 gcagaaataa tctgtggaag cccctttatc aaggctacgg ctagttgcgc aacaagctga
    12061 atgcctgctg cgataatctg aggtagagct tgcgtcagtc cagaagctaa agactgtata
    12121 atctgtacag cagattgtgc aatctggggt agattttgaa taatcccctg cacaaggcta
    12181 ataatgattt gaatgccacc ttgaagtaac tgcggtaaaa actgtacaat tccagataca
    12241 aaactcgtaa tgacttgagt agctatctgc agaacagttg gcaacatttg agtaattccc
    12301 tgtacaagat tcaccaaaat agctataccg ttgctaataa tactaggaag gttagcctgt
    12361 aaactattcc caaaactatc aataatttgc tgggcttgct ggataataag aggtatattt
    12421 tgaactatgc cgttgacaac atttaataat agctccattc caacagaaat aagctgcggc
    12481 aatgcactcg caattgaact aacaaaacta ccaatgattt ttattgctga actaattaaa
    12541 ttcgttgcat tttgtccaat accttggacg agactcgtaa ttagctgaac gccagcttga
    12601 attataactg gtaataacac tgcgatagca tttgcaaatt tagcaatcaa ttgagtgcca
    12661 ctagctatca aaactggtat tttagaagta attcctttta caaggccttg aataatgcca
    12721 ggaccttttg taactgcggt gttaagtagc tgctcgattt gtgcgccaaa ctgactatta
    12781 atcaaaccaa gtcctgccac cacaagacct agaatagcgg ccggtcctat ggccgccagt
    12841 gctaaactca caagactgga cattgcgctt gtcatagttc caagcacaga tagcccacgc
    12901 cctgctgcgg tagcaaaaac gccaggtaat ccgcttagag ttgccgcaaa ggcaccaaca
    12961 acgccgctgg cactagctat cccactagaa attatgccgc caaacgcccc gacagaagtc
    13021 cctaagcttc ctaaagctag accaactttt ccgaatagag aaagcaaagg cattatcgtt
    13081 gatatagcgc tagcggggtt catcactgcc caaagggcaa tgactttagg agctaaagaa
    13141 gtgatttttg cttttagatt atcaaaagcc tgctctgata attcaccagt atgtgcaaaa
    13201 tctccaaaaa caatattaat aagagcaaac acctctttaa cgctggcgcc taatgggcta
    13261 aagtcaatat tgatagactg ttttagccta gcgaatgctg caactgcatt tggaataaga
    13321 gaattaatcg tatcaaaaac actggttatt gctggcttca gactaagaag tgtttcagca
    13381 atggtcttca tgccattagc tttagccgct tcatcaaagg ctgaaatcat acctgctacg
    13441 ccttttacga cggcggtatg tacgttcttc catgcagttc ggattccacc agccgatgat
    13501 tgggccatct ctgcaaatcc gccttgggca tcgttaagct caatcatttt atctgcgaac
    13561 tcttgtgcag tgattttgcc atcagataag actgatttta aatcttgtac gccattttta
    13621 ccaaaaccga aggcttccgc cattttagac attaaacctg gcgcagcttc tgatacagag
    13681 ttaaactctt cagcttgaat ttttccagac cccaacgact ggttaaactg cctgagtgct
    13741 tgctcagccc cttcagttgt tgccccgtaa ccgatcattg cgttattgaa ggcgagggct
    13801 aaactagtcc ctttatctaa acttcctgtg gttatggcga gctgttgagc gctttttaca
    13861 gcactgtcta gaggagttgg cagaccttca attccttttg atagcttatc aattgatgcc
    13921 ttagattgtt cagcagaata cccaaatagc gccatcgttt tcggaaagcg gttcatggta
    13981 tcaacgcgac taaccgcccc gtctattgcc ccagtaatag cgtgcatagc tttttgagca
    14041 acagccatta aactaaaggc ctgcacgatg ctcatcactg tacttttgag tctctctcca
    14101 gcagaagagg tattggcgaa tttctggctt attccattca aggaagtagc cgcagaacta
    14161 gacattctgc taaaaccatt gctaagactg ctccctattt tacttgataa attagctaaa
    14221 cttgaggtca gccgaccaaa caaactagta ctcactttgt ttgcgaaagc agacgcctta
    14281 gctgatacag aactaaaaaa attattccat gactgtaagg ctgggttcaa gacttgctga
    14341 ccaagtgaat tagaaatctt ccctccaaca gactgtatag agctattcaa ggtagaaacg
    14401 gatgaggcaa tttttctaaa cgctgttccg aatggtcgcg gaagcttgcc tgcgaccgtt
    14461 tcgaatattg cagataagtt attaagctta ctacttgccc tctgagttaa gatatcaact
    14521 ccagtcgcag ccttggcaaa tgcagatctt atcttaccaa tacccacaag attctgaagt
    14581 tgcatttttg tttgattaat gaaaccggtt aagttacccc gtattttgtc aataacactt
    14641 gcaactggaa taatgatttt ttgaaaacca ttctttatgg gttcgggaat tttttcgcca
    14701 atggaagctg ctatgcgttg aatttcacca atgctcagtt ttaaaccagt agcgtaggca
    14761 gagccaagtc tcttcccgag cgattcgccg ttgttcgcca gttgggccat gatttgtcca
    14821 atgatttgaa ccattttatt actactgtta accgctgtat cttgggcttt tctgaaagta
    14881 ttctgagtcg tactaacaat acgagccatg gcctgctcat agtcctttgt gttggcacca
    14941 acatcagcga aaatagaacc atcaaatgtt cctggcatct actcctcctt atctatctat
    15001 tttgaaaatg attattaagc atttgtattc tctcaacaat actgctatca ctatcggctt
    15061 ggctacggct agctttttga tacgatcttt tgatagttag cctatgctta tcgtatttga
    15121 gcttacctac atcaaccttt ttagcattta atgtatatct aagctttaga gacaattcag
    15181 agaggttctc gcgctcagca agctgcttat actcaagccc ctccataata gcctctagct
    15241 cccacttagt acatttatag atagtatcaa tgtctgtgag ccctagccgt gcgcaattta
    15301 ctaagatact gcgttgctca ttcttccaat catgtcttcg ataatttgga tttgagttgc
    15361 gtccatatcg tccttcgctt tgagataacg agctgatttc tccatgtttt cgatatattt
    15421 caaaatcttc gctctgaaaa aaccagaatc aaccatttct ttttcaatct cagcaaacaa
    15481 cccttctgtt gttccttctt catcaacagc ttctgcaatt gcatctagaa tttcatcttc
    15541 agttagcgct ttttttccgc ttcccgcaga taaacgcaca aggtcaacaa tggcgctttc
    15601 attacgctct aagatattga aaaacaaagc acccacacca tctgcattgc gctctcctgt
    15661 ttctgggtta attgttccta gtttattatt gatcttaaac atagttttaa aatcaaattt
    15721 aatatcgata tttcgttttg ctgctgtaaa ttccattatt ttatctcctt tttaaatcaa
    15781 aatggggtag cagttgccac ccctgtgtgc tatttagtga tattatcgta gtcgccagta
    15841 gtatcacccg gattttgata gccgtataca ttttctagca tttcaatttc ttctttcgtg
    15901 agagggaatt taccatcttg taaggcccct acaatgttag cggtgtagga catttctact
    15961 aagtctgaaa taccagtacc gcgttcgatt tcgtcaatct tggcgtaccc aaacttagca
    16021 gggtaaacat ctttcttggg tccagtcgat tcaggaattt gaatctgttc tttgacactt
    16081 tcgtcggcaa taacttccca aattttgata gatttacctg ttttcttagc ttcctcgatg
    16141 acagcaacag atggatctgt cggtacaaag tacgttgtca aatcaataga gtgttcatct
    16201 gtagccttct caataacgcg accttgttgg gtttgctcat caatgtattc accacccatg
    16261 gttgtagtac catcggtacg ataggctggc aacagagcct gacttttctt tggtgcatca
    16321 actgattgta taaagtaaaa aatctttttt cctacaatcg gtttacctgt tgtaatttca
    16381 atagttgttc ctttttttgt gtttgccatt taggtcccct ttaaaatagt gtttctgtaa
    16441 tgttgatagc aactctatag acttctcgtc ctattgaatt atctaccaaa atctgagcct
    16501 ttatttggtt atttcgccca agcagtctaa gcatgcgaga ttttatctct tctgcatcca
    16561 aacgactatc gccaggtaag aaagcatcga tattcaggct aaaatcatca ataactgctc
    16621 cagtttgagc tgtttttgac aagtctgata tatttgtacc tacaacaata aaaggctcta
    16681 aaacgtctga tttaggcaat ttaaaataga ttggtatgtc taaaactccc aatctatttt
    16741 ttaccttttt taaatatagt gtttccagtg agtaatccat gcatcacctc ttaaacattt
    16801 ttttgatatt agccattagc acaggccatt cttttctcag ggcagggtct aaaaacgatt
    16861 gtgcttccat tttacgagta cctaattcaa gataaataga atataaagca ggagaaacca
    16921 ctctatagtg taagagtcgt tgttgctcac tgtagatttg agctctcagc catccagtgt
    16981 caaccggggc tagtatttta gcctgtctct caatcctagc agctgattta ctaagctctt
    17041 tatctacagc gattcgtact gacttctgct tgcgctcaac gctgcgtaaa aacctatcta
    17101 ggcctctcat ccgataaata agactcatac ataaataacc gtgctatttt tatggtgtgc
    17161 tagtcccttt atcaacctcg attttccctt gtagataatc ttgctaaagc cgtcgtaatg
    17221 gccttgcaag tgcaacttaa aagcattcaa atcatattta ccaaatagcc ccatctgttc
    17281 agattttgtg aaagtatttt ccatacaggg gattttcccg ctaggttttt caacagttct
    17341 tttatctaga aaatcgtcct gttcatcgac atacactaag attactctat ctttatagat
    17401 cattgtgtat ctcctaaata aatcttgcta cccctttgcc tgaatatacc ttcccaatag
    17461 cagcgcttct gagtgttgat tcatactctt taaggtaact gtcccactta aaagtctttc
    17521 cttcttcgct atcttcaacg gctccttctg aattaatcct attaaaccgt ttaatagcaa
    17581 catcacggac aataaacctc aatctatcag gaattttggt gatttcagtt tctgagtatt
    17641 cattaagttt agctagcaca cgctctttac tttcatatat agcaagggtg atgagctcat
    17701 cttgcgcacc atcacccttg gaaataccta taaagagttt gatatcgtca ataagttgtt
    17761 tatcacccat ataaatagcc tttaaccacc aatgccgggt acagcagcag cttcgattgt
    17821 tgcctctaca accccttcag gaatttcagc aaacagtaca ttcgccccaa agaaaacaga
    17881 ttcataggta agattagaaa gctgacgatt acgagctgca gcaattaaac ctgtctcatc
    17941 agtaaaatca gcaaacaagc cgcccaagtc tcccccttta acatttaaag atgcaaaaac
    18001 tagattttct acagccgttg agtagatttt accctctggc acagatggca taacaatcac
    18061 attttgcata cccaaaaagt tcttaagcaa tgtcattcca aaaacattag aggcatccgc
    18121 acctacttta gtatctccaa gatagttagc tacgtctaaa ggagagacaa aagaaacaag
    18181 cggggaaccc tcaaactcat taaaagtagc tagcttagcc catgatgcag acagcgcttt
    18241 ttgaaggcca acgcctttaa cttttgttgg ttttgttttg aggaatgtaa agaatgcatc
    18301 cttaattcca ttctgaagct cacgcataat gcgcttatct gcttcagtaa tagcacgagc
    18361 tgcaccatgg cgagcaattg cctcagctgt agttgcacga cgtttcttga accacttcac
    18421 tgtatagtct ttatctttag ttcgagtaac cttagacaga gggattgttt ccccttctcc
    18481 aggatcagtt tgatctaaag tcacttccca cttataggtc tgaattttta gatcgttagt
    18541 taatgtttca cgacgagtaa cccctagcaa ttttagtaaa tcattaatat ttttggaaaa
    18601 cttgttaaca aaatcaattg atttaatatc tcctaagtcc gccatagtgt ttaagttttt
    18661 ttcagccata atattcccct cttaaaataa gttacgattc tcagcaatta aacgcatacg
    18721 ttcgtcgtca tcctctatcg ccatgatgtc agccttagtc ataccgaccg agccatttcc
    18781 agttcgtggc ggtttctgag ttaaacgatc gttaacacgt ttttcaacag ctttatcaaa
    18841 aatagtttgt aaattatcaa tattggcctt aacctcttct gcagtagtgg ctaaaacaat
    18901 atcaataaaa tccaatggca atcctttctc cacaagcagg gaatgcgtct caatgcgcat
    18961 ctcacgctct gctactgctt tttcacgctc tgcgatagca tctagacgtt tttgttcctc
    19021 ctctttagcg cgctcatctt ttgacaactt ggccaaacgt tcaccttctg tacgagcttt
    19081 ttcaatagct gcggattgtt cagattccca tttagtgcgt tcagcagcca tcatttttga
    19141 gatgtctgcg cgagtaaaag ttcgctcata ttcatgctta ggatgttcaa cagcttcttt
    19201 ttgagtgtcg acttgctcag ttgtctctgt tgttacattt tcttctgcca taactttctc
    19261 ctagtggtta cgccaccaac cgatagtcta gctttacgtc ctgcgacgaa acagtgtagc
    19321 ttttagtgtc atcaacaaag tttggacaca ataaaaagcc gtattgctac gactttggtt
    19381 tagatttgta aagaggtcaa attcgacacg gttaaacttt atttccccta cttccgtttg
    19441 tagtttttct taatatagtc aaccgtgtca ccaattgcct tgataactga ttggttatct
    19501 aaagtagcag ctttaacagt cgctaactct tcgtttgttg ccagagcgtt tcgttgaacg
    19561 attgatttta gctccatgat ttgtttgttt tgatttttaa tagcttctgc ttgcatggca
    19621 ttctctgcaa caagcatcac aaccgctgtt tccaatttac gttttttctt aatgcgctta
    19681 ttcattgttt tatccttctt ttttcaattc tgcaataatt gacttaaccg ctattgctgc
    19741 aatgccaaca atcaatatga gtaccaatac acctagtgcc actaatacca tttgccaaat
    19801 aaacatattt tcctccttga tagttttaat agggtgatgt ataattgaga taaagaagga
    19861 tgatggtcta acgcccatga agcagtttac tgtggaggcg gtgggtcatc ctccttcttt
    19921 ttctaataca gctaatacct catctttatt tttgataatt gatatatcaa gacccctacg
    19981 atctatcata taaatatgtt ctaattgccc cattatctct tcaaatgata aaggggtttt
    20041 tgttatatca aaaatgatat tagttgcctg cttttttgct tttcgtagat tgccatcaat
    20101 gacgttttta cccgaacctg tgatttcttt tagatcaaaa ggagctccat caactaaata
    20161 atcaggagtc ttgatatgtt caggggaatt aactcttggc accatgtcaa cttgcaatcc
    20221 tgtctttttg gataaccaat tagcaactct atattcataa ttcgaatgat caagaacgac
    20281 actatggcca tctactttgt aaggagtgcc attttttacg tactcattta gtagtgacag
    20341 ttgtggttta tgctcatttc catctatcca atctgaggtg acatccttaa aatacttagt
    20401 gcttttatca tcaattggtt ctacttcaat acttagctca tcttcatcag gaataatagt
    20461 tgttctgcag ttgaaatgat agggtgctac attaattcca ggctttagct cagataatag
    20521 ctttcttttg ttttctttag caattgtacg gcatatctca gttgtcctgt catcaagtct
    20581 aactaaatca cgataatact taagtcctgc attcaagtag cgcctagcgg tagcattatt
    20641 aatcaccata gttccatcag ttctgattag tgtttcagcc ctgtgattag caacattaaa
    20701 tcgcttagct aaatctctgg ccatcgctct aggatgctcg ccacgaacaa aaccttgttt
    20761 taatctcttt tgaagattct taacaagatt gtcagtattg ccccacaact gttctgaata
    20821 gttataacca tcaaacgggg ttctaaccag ttcttctaaa actggaccat tgattgtccc
    20881 tgaccgtcca cccattgctt ttttataagc atatgaggca acttttttta aatgattttc
    20941 aaatgctgaa tcaagtacac cttttagtat ccccgcacga taaacaagct caagatttaa
    21001 tgcatccatc cttgtagctc ttgctgatac atactgctca ttaagtcgtt ttagcagctc
    21061 aggatctttc tcagcttgtt tacgatactt gttagcatta gctacgtaat ctgataaatc
    21121 ttcatgacgt agttttttaa cgacatcctg ataagtcatt ttgttctctt cagaatactt
    21181 agtataaaaa tcaaacaatt ccttttgtaa ctcaaaagcc tgttcattat ataacttctg
    21241 cagttctgaa aagacatcta aatcagttct gtctaaataa cttagaatat ctttttgacg
    21301 cttttgccag taattaaggc ttttctgccg ttggttcttc ttgaccacta gcatcaccta
    21361 ccaatctagg ctccggtaaa gattgctttt tatcagcttc ttctttcaag cgttcaagct
    21421 ctgcttcagc atctactcct gtgacagtat ttaagatttc aaagatagtc tgatcgctaa
    21481 caatgccata aagattttgt gcagctgtaa caatttcatt atcgttttga ggaagattag
    21541 gtgtgaaaac tatactcgta tcatttacaa ggctatatgt agttgcttca ttccctttga
    21601 tggcccagat attagctgct aagcgtaagc gtcgcattaa tcctttttta aacaacctct
    21661 cttgcttctc gcgatagttg tcagaagcca taagcttata cttcattgat tcaccagatt
    21721 gaactcctga aaatttcata tcttgtgtat ctggcgtaaa agtaaacctc aaaatgtctg
    21781 caactaatct atttttgtag gcttcgctac cggcggtatc atactctttt ttgagaaagt
    21841 acgcttgcgg tttaacgcca tttggattag gattatcgtc taaaattaac acttgggctt
    21901 ttttaaaccc aattgagatc gctaaacgac cattaggatt taatcggcca tcatctaagt
    21961 agtcattctc atcagctcct gtgtaagcat taccagctat tacaagcaac gcattgactg
    22021 aatcttgttg aaagttagca agctctgatt gagataaatc ataggcgtca atattatcaa
    22081 gtacagactc ataagccccc gttcgctcct cgttattagc gtattcgttg actggtacac
    22141 ctctaaaaaa atgtccttca taatctttta atcgcatacc ttttgtttca aggttatagt
    22201 cttcgtaggt ataaattgtg tcggaagtat atgctttgat aatctgttta cgtttacctg
    22261 agccgtaatc tatgtcgtag aaatgaacgg ccatcaacga atttcgctgg tatgtatcat
    22321 catagataac aaaagtttgc tcggccggga gctggtagag ttttacttcg gtttttttgt
    22381 catctatttt ctcaacagtt aacagctcgt aggctcttcc ataaattgat aaatctgttt
    22441 ttattttgac gttgtggtag tcctcattgt ttctgaccga cataaggtca atagctgcct
    22501 ggaggtcttt attttcattt ttgtactcaa cgggaacgcc aagcatataa ccttgctcaa
    22561 ataccgtaat atacttagca aaatcacttg caatacgatt atccgctgcg tatttatctg
    22621 ttttagcagg tctatacttg atgttattat ccccaagata gtatcgcttt aactctttca
    22681 aacgctctaa ttgttctgct ttaaaccttg aaatgtaatt cttaagttga tctatccaaa
    22741 gttttgattc atagtcaatt gcttcaaagt cttcttgcag cataataaat tgcttattag
    22801 cattctcatt aaaacgagtt cctgctaaaa attgtttttc ttccaaagtt tcacctcatt
    22861 cctaaaaata atatttagca tttttcatgc gcttacttct atccgccgac tggtatattc
    22921 tgtcttgtac ggcatatctt atggcatcaa tgcagtggtt atagctgtca actggttcgt
    22981 tggtatactc attagtcttc ttgtctttct tccaagtgta attttcgagt tcttcaatag
    23041 tcttgacaca cctttcatca acaatccaat catattgaag caaatactgt attccttgca
    23101 taacggttcc aggccctttg gtaacatcaa tcattctagg aatacctaaa ttcctcagct
    23161 cttgattaga tttcttttca gccgaatctc ctctgatttc ttctttggcg tagccgaggt
    23221 cctttatagc atttgctatt tcgtcattgg tcaaattctt cctgacatat tcctctaaga
    23281 tgtataactt cttgtttgcg tcatcgattt taacatgcaa aagtgccgaa ggatcattga
    23341 taaatccata gtccaaacca aaaaaagaag gcaagtgtga taacttgtct ttgtttaata
    23401 tttgcttgtc atatttggga aaaattagtt tatcaagtgt agcaaactgg ccaagagcat
    23461 atattttgta ataagcttca ttcctattgg ctagttcctc gatattttct ctcgtgacat
    23521 catctaagaa gcggttgtct ttataagttg tttgatagac aactgtattc ttaggtgtct
    23581 taacgaagaa ggctttataa acccagttta cttttgatac cgggttaaac atcaagtata
    23641 tttgcttctc tagatgtttc ttatctctta aacgcaaggt caactgcgta taatcatcaa
    23701 gcgtaaactc actagcttct tccataacca catcagatat acccttaatt gacttaatct
    23761 tctctgggtt gtccataccc ttgaaaatga attctgcgcc atttgggagc gttattctaa
    23821 aagccgacat atttatctta catttatcca agatgccgaa atacgacaaa ttagacatga
    23881 tatcagcaaa tacagagtct ctaacagttg caccgacttt tctgagaact aatatctttc
    23941 tgggatgttt gaatttaggg ttaagtgctt ttaaaattat cttttgaaaa acaccgtgag
    24001 actttccgct agacgcccca ccataatgaa cttccgtgaa gttgctatag ttgtaaagtt
    24061 tgtcgtagat atgtttgtta aaaactttgc taggatgctt gatcacgata ttaattttag
    24121 ggcgctgttt agtcgtcatc ccactcacct acgttaatgg ttacatctga gctgacatcc
    24181 atttcaacct tgtcagtaaa taacctgtac cgtttgccta gtagctcagc tgccttgatt
    24241 ctatccttgg caccaacatc gatgtcaact atcttctgac caaactctcc aacgctaatg
    24301 agcgtctttt cttgttggtc tcctcgcata attgaagtga gatattgtag gacttcttct
    24361 tgcgtagcaa tcttttcaga ttcaagtttt tcaagccgct cgtctatata agctttaatg
    24421 tcaggtttgg tcaagttttc ttgacctatt gaccttgctg tctttttact ataccctgct
    24481 ttaatagccg ctgctgtcgc gttagctgag atgatgtact catctgcaaa acgcttctgt
    24541 tttagggtta atttactcaa ttttccatca cctccaagca tagcaaaaag gcaagacact
    24601 atctgcctta ccttcaaact catactacca atttatcatc aaaaagatga caattccata
    24661 catttttgtg tcacattcct atttttttgg aaaatatttc tagaatccgc tctcttttgc
    24721 ggtaaataga cttacgcgac agatgtcttg tataggcaat ttcttcccaa gtgttacttg
    24781 aaccgacgcc ccacctaaga ttaaaaatat cagttagttc ttcatccaaa agatttagcg
    24841 ttgcaataac tgcttctttg aaattggata gaccctttag ttccctatct gaatcccacc
    24901 ttgcaaccac atcctcagta acttttgaaa caaaatttgc tcttcctcca ccgatatttt
    24961 tatctacttc tgtattcatg tcagtttgta gctcaagttt tcgaagtgca atcttgttat
    25021 caataaaacg ataatcaaac aaccattcat caaaagcctt tagctgtgca ttagataatc
    25081 tactcatccc gttacctctt ccgcaaactg ccacgcccaa tcaaaatctt ttcggatttc
    25141 tcgttccgtt aagcgcatgt aatctgtaaa attattagat gagtaagttg caacaattct
    25201 tacttttcct tcaacccatt tttcaagtct caaagctatt tgcttagcat tcggattagg
    25261 tatctccacc gtatacagct tttctttttt gattgtgtat ccgaattgat gcatgttaac
    25321 taacgtctgg ataggcttaa atgcgctaaa attcataaaa acgaaaaaat catctttttc
    25381 ttgattgtcc cattcggcta tatattccca aatgtaatat tccaaattat ctttatgttt
    25441 ctcataccaa tccgccacat actgcagtac ttctggtttt agcgaatcct ttgcttgtaa
    25501 tacgccttgc ttgtggccaa gataatagct aatgtcgttc tcaataccaa attccttaaa
    25561 aataccttta atccagacgg ctctgtcgtg ctctggtagt tctcgcattt tagcaataat
    25621 atttttaaga tatttaggtg actgccctgc gtatccgtct ggttttattt ttgttcgctc
    25681 aagatcataa aaggcgtcaa caccagcatg atttacatgt actccaccat ttgaaaagga
    25741 cgaattgata ataccttcaa cccacacttt atcgcctatt ttcgcttctt taatgttcat
    25801 ttttgcatct cctctaatac ttttaaaaaa cactgctcag caatgacttg atcactgcct
    25861 tgccataagt cgcctgtcac ttttgtgata atgtcactga tgtttttctg cgcacgatcc
    25921 agacgtttag cgatacgatt gcgatcaatt tgtttttttg ctttgagtaa gtcctggatt
    25981 aatccatttc tctcagctac ccacgaccgc atgtcttggc acatatcgta tctgtcaccg
    26041 caatgtctga tgtgacatat agtatcgatt actttttcgt tagtgttcat tttgtacctc
    26101 ggttaaaatt caatgcactc atccaaaacg gattatcttc tgcaagctct attaacagat
    26161 ctacatctac aatttctctt tcaacaagtt catcaagtat ttcctctttt gctaatgctc
    26221 tgtttgcata gtcgattggt aaagtcatca ttccagtttt attttcagcc attatcctac
    26281 cctcattttc gttaactcaa tcctctaaat tttcttctcg acaaattcgc actacaaact
    26341 tatatttttt gtctggcgat ggcagaaata cctgcgctcc aaattgtcct ggatcattgt
    26401 gcaaatcgtt gataatttcc ataatctgat caccaactaa aagtggcgcc ataaattctg
    26461 acattttcaa ttcgtcaagt agttctttta ctttgtctaa tttttcaaat ttttgtttgt
    26521 tcatttttca tctcccgctc cctagtatat ttttctttaa ctgttgcttc gcaagaatcc
    26581 caaaacctca gcatgtctgc ttttcgcgta aaggttttct cttcaaactg aggttttgcc
    26641 tcaaaattct tttctctacc cgtgtagatt ctaacgacat attctttttt catctagacc
    26701 cctaactgcg ccttaactgc ttcaagtaag gcgttctgat ttttttcttt gccttgtaaa
    26761 atcctaagta ctttttcatc aactgtattt tctgcaacaa tgtggtgcac aataacgggt
    26821 tctgtctgcc cttgtctgtc taatctggca ttagcttgtt gataatattc aagactccat
    26881 gttagcccaa accaaacaat aatatgccct cctttttgca gattaagccc atgcccggct
    26941 gactgtgggt gacacagaag aattggtatt tttccggaat tccacttgtc aactgacgtc
    27001 aactcttcag cctgagggaa tcgtttctta agcctttcaa gatcatgttg atactggtaa
    27061 aaaactaaga ttggctggcc ttggctttct tcaacgacat tctcaagcgc gtcaagtttg
    27121 tcgtcgtgta tagcaactgt tgttttatca tcatcataga tagcgccatt agccatttga
    27181 agtaatttat tagccaaaac cgcagagtta gccgcagata tctccttatc cttaaactcc
    27241 aacaccaaat cagcttcaag ctgtttgtag gctttcatat tagataactt aactgataca
    27301 acgttgtcgg ttcgcggcgg taacttgaga tagtctttag ctttcatgct gatacagatg
    27361 tcctcaatct tgttatagat ttctgcttct gcaccatccc taagtgccca actgtaaatg
    27421 attaggccat tacgcttatc aggaacaaaa tacttgtctt taaatcgagt ctggctcgtc
    27481 tcaagcctgg cgcctctgtc catcagataa atctgcggcc acaaatcaat caaactgtta
    27541 ggcgctgggg ttcctgttag tcctacaagg cgttggactt tcggtctaac ttttcgcaaa
    27601 gccctaaacc gttttgactt actagactta aagcttgaca gctcatcaat aaccacaaag
    27661 gtaaacggcc atttagtctt gtagtattca acaagccaag taacattctc acgattaatc
    27721 aaatagatat cggcttctgt ttctaaggct tcaattcgtt ttccctcact ccctaaaact
    27781 ttagagtagg tgaaatcaaa atgccatttc ccaatctccg ttgaccacgt ttcttccgcc
    27841 acttttttag gggctacgat taaaatctta tgatcctcgg aaaaaatatt ttgaatctca
    27901 tctattgccg atagtgttgt cagcgtttta ccaagaccca tgtcaagtaa aaggccacaa
    27961 taagggtgct ctactatcca tgtcttagcg tattcttggt actcgtgcag tctcacaccc
    28021 agttctccat ttcttttaag gctatgtcca ctgattcgta ggagtcaaca acccaaacgt
    28081 gctgcccagc ctcttttatt tttttgtgca tggcaacttg gctgggtctt ggttttttac
    28141 caggtgcttt gacctctaca aaaaaggttc ccgtgttcat gacaacaatt ctgtcaggca
    28201 ctcctatcgt ccctggactt gcaaatttta aacacagccc ttttgttttc tttttcaaat
    28261 aattttcaat gtctttttca gtcctcatct ttcctccttt ggtcaataaa ggtcagggtt
    28321 accgtttttt tcaacttatt ttctcttt
//
LOCUS       DARYLJ010000033        28033 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYLJ010000033 DARYLJ010000000
VERSION     DARYLJ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28033
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(298..813)
                     /locus_tag="TU746_001293"
     CDS             complement(298..813)
                     /locus_tag="TU746_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL0891639.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
     gene            complement(815..2326)
                     /locus_tag="TU746_001294"
     CDS             complement(815..2326)
                     /locus_tag="TU746_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL0891640.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            complement(2316..3041)
                     /locus_tag="TU746_001295"
     CDS             complement(2316..3041)
                     /locus_tag="TU746_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL0891641.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            complement(3570..3992)
                     /locus_tag="TU746_001296"
                     /pseudo
     CDS             complement(3570..3992)
                     /locus_tag="TU746_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4136..4642)
                     /locus_tag="TU746_001297"
     CDS             complement(4136..4642)
                     /locus_tag="TU746_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891642.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            complement(4644..5570)
                     /locus_tag="TU746_001298"
     CDS             complement(4644..5570)
                     /locus_tag="TU746_001298"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891643.1"
                     /translation="MNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVAREKL
                     INTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDNGA
                     VSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGRGK
                     SGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSFDQ
                     IGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSMES
                     TGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            complement(5712..6134)
                     /locus_tag="TU746_001299"
     CDS             complement(5712..6134)
                     /locus_tag="TU746_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891644.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(6457..6717)
                     /locus_tag="TU746_001300"
     CDS             complement(6457..6717)
                     /locus_tag="TU746_001300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891645.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(6732..8540)
                     /locus_tag="TU746_001301"
     CDS             complement(6732..8540)
                     /locus_tag="TU746_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891646.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(9181..10080)
                     /locus_tag="TU746_001302"
     CDS             complement(9181..10080)
                     /locus_tag="TU746_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL0891647.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(10092..10901)
                     /locus_tag="TU746_001303"
     CDS             complement(10092..10901)
                     /locus_tag="TU746_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL0891648.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TU746_001304"
     CDS             complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TU746_001304"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL0891649.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(11736..12476)
                     /locus_tag="TU746_001305"
     CDS             complement(11736..12476)
                     /locus_tag="TU746_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0891650.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(12480..13778)
                     /locus_tag="TU746_001306"
     CDS             complement(12480..13778)
                     /locus_tag="TU746_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL0891651.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGTCFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(13790..15136)
                     /locus_tag="TU746_001307"
     CDS             complement(13790..15136)
                     /locus_tag="TU746_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0891652.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(15581..17026)
                     /locus_tag="TU746_001308"
     CDS             complement(15581..17026)
                     /locus_tag="TU746_001308"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL0891653.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(17628..18341)
                     /locus_tag="TU746_001309"
     CDS             complement(17628..18341)
                     /locus_tag="TU746_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL0891654.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(18469..18975)
                     /locus_tag="TU746_001310"
     CDS             complement(18469..18975)
                     /locus_tag="TU746_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL0891655.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            19358..19636
                     /locus_tag="TU746_001311"
     CDS             19358..19636
                     /locus_tag="TU746_001311"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891656.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TU746_001312"
     CDS             complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TU746_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL0891657.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(21225..21671)
                     /locus_tag="TU746_001313"
     CDS             complement(21225..21671)
                     /locus_tag="TU746_001313"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL0891658.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(21873..22640)
                     /locus_tag="TU746_001314"
     CDS             complement(21873..22640)
                     /locus_tag="TU746_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL0891659.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(22802..24598)
                     /locus_tag="TU746_001315"
     CDS             complement(22802..24598)
                     /locus_tag="TU746_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891660.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISAPKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(24598..26307)
                     /locus_tag="TU746_001316"
     CDS             complement(24598..26307)
                     /locus_tag="TU746_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891661.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(26300..26749)
                     /locus_tag="TU746_001317"
     CDS             complement(26300..26749)
                     /locus_tag="TU746_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0891662.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            26959..27978
                     /locus_tag="TU746_001318"
     CDS             26959..27978
                     /locus_tag="TU746_001318"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL0891663.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         8373 a         6755 c         5154 g         7751 t
ORIGIN      
        1 ctctattttc ctttttcagc ccttgtatac tggggaggat ataatagccc ccctaaaata
       61 aaatgtgcta agcaatatga gaaacaggtc gctgagcttt tcttttattt gccacaaggc
      121 acatacgaca gctgttaaca tttaaataga ggttaaaaga taggacaatc aaagcctgct
      181 gattgctgac aataataaaa gcaccccaag gcattgaccg acttagccaa gtgctggggt
      241 gcagtttttt catatgacct tttagttgtc atcaaggact ggatcgatag cctctagcta
      301 gagagtagcc tttagcctaa cttggccgac ttctgcccta gcagcaactg ctccagcatc
      361 agcaagacgc atatcagcaa tgtcctgtga gtttgtaaag acaaccataa cggtgctgtc
      421 tttttgagca gcttcaagca ctggcaaaga gacctgagcc aataactgcc cagctactac
      481 ctcctgacca gcaacaatat cagagctaaa ggcagcttct cccagctcaa cagtatcaac
      541 accgatatga atcaagacct caagaccagc tggagtaacg atgccataag catgcttggt
      601 cggaaaaacc gtcatgaccc ttcctgttac gggtgcataa atagcgccct cctgaggaat
      661 aatagcaaag ccatcgccca ttagcctttc tgaaaagaca ggatcactga cactggtaat
      721 aggaactaat tgtcccttag ccactgataa aatacgatcg cttaacgcat cagctttttt
      781 tgctgataat aattgcttcc acttctttat catgttaatc ttctctacct aatagttgat
      841 tgatttcttg actatacaag atagccttac caccataaat agcctgaatg ccatttttaa
      901 catctaatac agctgttgct cccagtgagg ttaaaacatt cttgttaacc aagctgctat
      961 ctgacagaga cactctcaag cgagtcgcgc aagcggttac atcttcgatg ttagcttgtc
     1021 ctcccaaagc ctcaataata gctaatgaca cctcacgaag tgatgagctt tgagtattag
     1081 tagtctctgc ttgtccttct gcttctacct gagctaccat tcccggtaca gcaacctgga
     1141 atttgctcac aaagaattta aagacaaagt aataaaccat aaaccacacg ataccaacag
     1201 ggataacaag tagccagttg gtatgatcat ttccttggaa cacaccaaag attaaaaagt
     1261 caatcaaacc acctgagaag gaattaccga tacgaatctt taataaatca gcaactaaga
     1321 aagaacaacc atctaagaaa gcatgaacta catagagcca aggggctaca aataaaaagg
     1381 caaattcaat aggctctgtg atccctgtta gtaaggaagt caaggcacta cttgaataaa
     1441 agctaccaac ctttttacga ttagcctttg gaatagcgtg atacatagca agacaggcag
     1501 caggtagtcc aaacatcatg gttgcaaaac gtcctgcaaa aaagcgtgtc ccgtaagtaa
     1561 acaagtcggt atggttagca tcagccaatt gcgcaaagaa gatattttgt gctccttgga
     1621 tagtctcacc tgctacaacc tcactaccgc caagtgatgt ataccaaaac attgggtaaa
     1681 tggtgtggtg cagccctact gctcctgtca gacgtaaaaa gaaaccgtac aagaatgttc
     1741 cgatgctccc catatccgca attttttcac caaacactac taggagattt tgaataggtg
     1801 gccaaatgac atagaaaaca ctaccaatca caatcgctgc caatgaggaa acaatcggaa
     1861 taaaacgaga gccgccaaag aagcctaaaa aggctggcag ttcgatcttt cggtacttat
     1921 tgtgaaggct aacaacaact aagccaaccg tcaaagcccc taaaacaccc gtatcaatct
     1981 gagcgtcctt tgctgaaaaa agagtcagat agccgctaat ggttgccgta aagaccaaat
     2041 aagccacagc acctgaaaga ccggctgttc ctttatctcc gttggctaag ccaacagcaa
     2101 caccaatcgc aaaaatcaag gcaatattag caaaaacagc gttacctgct gtgctcataa
     2161 tggtaaaaat agcctgtagc catgcttgat ttaatatcgg aaattgtgca atggcattgc
     2221 tatttgacag ggccccacca atccccaaca acaaaccagc aactggtaag attgagatcg
     2281 gcagcataaa ggcttgaccc aattttgaaa atttcttaaa atccatgtga tttctcctcc
     2341 ttcttgagag ccgccacaaa gcgctctgca atttcctttg gtctggtaat agcaccacca
     2401 accacaatac cagctactcc caaagcctga acagccctgg cctcctctgg actatgaatc
     2461 ttgccctcag ctatcactga tacccctgca tcacacaagg cacttatcag ctccatatcc
     2521 ggacctgtcc cctgacgact ataaggcgta taccctgata aggtcgtccc tacaaaatct
     2581 ataccagcct cataggctac tagaccctct tcaagcgtac tgatgtctgc cataaacagc
     2641 tgctctgggt acttcttcct tatcgatcga ataaagtccg ctatcgctaa gccatcatga
     2701 cgctcccttt gcgtacaatc caaggctatc accgctacat ctaaggccgc taaggcgtct
     2761 acctctgcca tggttggcgt gataaagggc gcttgcggag gatactcctt tttgatgatc
     2821 cctatgattg gcagatccgt caccgcttgg atttccttaa tatctcgaac cccattagct
     2881 cttatcccta ctgctcctgc ttcctctgct gcctttgcca tcagaggcat gatacctcct
     2941 gcctctgaat agagaggctc gcccggcaga gcttgacagg aaacgatcag cccgtctttc
     3001 agagctgtca gtagctctgc cttgcttggt ttttcaagca tgctttctac tccttttatt
     3061 aattttagag aacgttcaca tctttattgt agcagatatt aaaacacttt caatagacag
     3121 cccactttta ggaagtactt tcattttcag agaaaaatcc ttgttttctg aaagtatatt
     3181 caatagcctt aagtatggca aagagctagc ctattgagct atttactaat tgatacaaca
     3241 acagcaaaac cttacaagac ataccttctt accataaaag cctttttgcc agccagctaa
     3301 ggccaaatac ggcaatatgt ctcaacaaga actaccttag gtcctattat tgcttgataa
     3361 gcttgacaaa gagacaaaaa agagagaacc agtccagtcc tctctcgcac ccagcttttc
     3421 aagctctaca atacccgtag tgggtaactc caccgcaagg gttatatata gaacttttga
     3481 ttgtacccaa aaataaccac ttttcaccta cctaatacag ctaacaacgg cccctaacat
     3541 agctgccctc agatccgcta tcttaaacat tatttcaaag gactgacata atcatctggc
     3601 agttttccct tccaatctat ccatttttgc tccgcaattg gaattagttt tcttagctct
     3661 tcttaggtaa acagttccca actggttgga tctgcaatta atgctattgg ggatctttgt
     3721 agaaatgctt tatcactagc tattttctcc tcttctgttg gcagccagca gttatttttg
     3781 acataaaaat ctatttctaa taaaaatttt cggtcacttt ccagtaattg gaaaagctca
     3841 ttagggagtt tatacactac tcgttgtaca gcaattcctc cttcttctct gactagataa
     3901 tattctccct gatgcttcca aacctgttgg ccataaccct tgatttcctc atattgacta
     3961 acatcttccc atgttaattg actgcgtgcc atgtgtgtta tctttcgttt ttatagctta
     4021 atcgataaat actgctcaat ctttttccaa taataccctt acctcgtctg attgaaaagc
     4081 atactctatt tttatttaag ctatttcaaa tccatttttc aagtattcat ctaaactatt
     4141 tgcaattttg agcttcaaga taagactgta cctgaggaat tttttgaaac atgtttttta
     4201 taaaaccaac catcgctttt tcatcatcag tcacgatatt ttcaggagat aaccttttaa
     4261 cagaaaaaac taaatcaggg atcataggat taaaatcaat ataaaaggaa aagttcttct
     4321 ttagtagttt gttgttcttt tgatagaaaa tatatgacac aacttgatat aattctacaa
     4381 cattttttga agttgagaat tgagacagta ttctttcagt ttcatgtggg ataatgctat
     4441 ctcctaaatc atacaaggga tacaagcagc gctcaataag cacatttata tctgtgatcg
     4501 attgaaaata tgagtcttta gcatttattt taaacccaga atcccctcta aagcacttct
     4561 ctaagtgtcc ctttgaacga gcatctaagt aaagttgtcg acgtctttca tcaacgtcat
     4621 tgttaaaaaa tgtttgtgtc atattaatta cctaattttc taattataaa ttgtccttca
     4681 acaatctttt tagtgccatc tttcaaaacg attgtaggat tattcaaggt ataaattcct
     4741 gttgattcca tacttaataa tacatcctcc aattttaagt tactagtatc aatagatggc
     4801 atcattaatt cagactgtga caaagccata tttttacctg cccaagtttt agcccctgga
     4861 atatttaaaa gtgaagaacc tggagtttta ccagtaactg ttctcacttc accgatttga
     4921 tcaaaagatt taacaaactg aggactatat tcatactgaa atgcaccaga caaatactta
     4981 ccttcatcta cccctttgat agcctctatc ataccggaag aaactaaatt accactacta
     5041 tcataaagta atgctatatc ttcagccata cttgttgcaa aatttcccga tttacctctt
     5101 ccaatggtac catattgctc aattgcatta tacaaatctt gaccattcac aattgatgat
     5161 gcacctgtct taatataaag ctgttttata ttctttataa agccatctaa atatatatag
     5221 ttcttatttg aatacatctt ataaaaatct gcttttgtag aaacagcacc gttatctact
     5281 gataattgag cataatcatc taatgtttct acaaattcat cagcctgtct tatcgaaacc
     5341 caactatttc ctttaagatc cctattaaaa atttctatgg ctttctccct aaatgtgata
     5401 agatttagat cagcattctg ttttcttaaa gtattaatta acttttctct tgctacatag
     5461 ctcttaaacc ttgagctctc tgttgccagc ctgctgtttt caaggttctt caaaagctgc
     5521 tggcggttgt aggtcggttt cgtcacccta gctgctattg gctcattcaa gctaaaccgt
     5581 ctggcggcgc ttggagacgc ttggcattgg cttcaaggtg acgagctact ccctgataag
     5641 ctgtcgcagg ctaattatta agaacatgct ttaaaatagc agagctaatc tcggctccgc
     5701 tatcttaaac attatttcaa aggactgaca taatcatctg gcagttttcc cttccaatct
     5761 atccattttt gctctgcgat tggaatcagt tttcttagct cttcttgggt aaaaagttcc
     5821 caacttgttg gatctgcaat taaggctatt ggggatcttt gtaaaaatgc tttatcacta
     5881 gctattttct cttcttccgt tggtggccaa caatcatatc gcaatttaaa agcaatctcc
     5941 cctaaattcc gttttccttg ctccaataat tcaaataaat catacggcag ctcatatact
     6001 actcgctgct cagctatacc accttcatta gtcactagat agtaagttcc ctgacgcttc
     6061 cacacctgtt gaccataacc cttgacttcc tcatattgac taacatcttc ccactctaat
     6121 tgactatgtt ccatgtatgt tctcctttac ttgtactgat atctttcata actccctctg
     6181 gcatatcacc cggataagta cgacctccag gtcgccacca gctattagca cccttttcat
     6241 taccacttgg aatagaaatc cctttctccg aaacaacctc tggtgaaaca tctaagcgat
     6301 agagcggatc attgccaaga taaccctcgt cgaagccgag taagctttca taaaagattg
     6361 atgcatagtc agcttactct tgttcctcct ttcttcagtt ttttatcata atttcatctt
     6421 aaaatttaat caattcgagc aatctaatct cactcatcat ctccttttcc tatttaggca
     6481 tacttctaag tccttcaaag tttttaaaat tggactatca tactgtgttg tatcatcaac
     6541 aaattgtcta gctaaacttg aaaaattaat attcccaaca atccgattat tatcaatatc
     6601 attagtcaaa acataaagat ctcttaatat tcctgaatag tttttttgct tgggatactc
     6661 aagttctatt aactctctaa gcctttgtgt atattgaaaa cagttattat tatccataaa
     6721 tttctccttt tttagttagg aacgatcctt atttcttgaa tccactccaa tggccaccga
     6781 ttgggaagta agacctgatc tccacctcca attaaggttg ttcctgaaga tttaaccgtc
     6841 tgtggggcaa ccttgccaat attcaattga ctcccctttg gtattttaat tacagcctca
     6901 tattgtctag tatttttcca ttctggaagt aaagctgtat ctatttttgc ttgtatacga
     6961 ttagttgcag gcaccgttgt gacaaaaccg cctccagcat ctgacgcccc tccaaaagtc
     7021 ctataaagtg ttatttcctc acctgtaata actgttctat agtgactatc tgtaaatgaa
     7081 tctgcaatcc aaccaggaag attttcctta gccccaactg ttactttact atctatttga
     7141 gttggatatt ttgtaacact ttcttttttt atatagcctc cgaaattaga actctctctc
     7201 gccagcctgc tgttctcaag gttcttcaaa agctgctggt gattgtaggt cggtttcgtc
     7261 actctagctg ctattggctc attcaagctg aaccttctgg cggcacttga ggcggcatag
     7321 cctgctagga tattccctac caaggtagct ctttgggcat cttgctcact gccgcctaag
     7381 agcttggtgc catgatagct ggcctgacca ccgataaagc cgccaacctc accgatcgta
     7441 aactctgtca agcccttggc aacactcttg gtctgaccaa tcagaattag tgctgcactg
     7501 gctgttgtga acagcccgcc gatctggtga taaagcctgt cattccccat gaacaaggta
     7561 tcccgaaggg gattggtagc cactgtaagc ccatcgccaa cgctacctag ataaatgttg
     7621 tgcccagcct catacaggtt cgacgcccca taagcaactg taccactgcc aacaacaaag
     7681 gccccaacca ccaagggagt cgctgcccct gctgtcatga cgatagccgc aaccccaacc
     7741 gctattgtca caaggctgag tgctagatct atccagccct gcttggccct gtcctctgca
     7801 gctactgcct caaaacgggc atgatcccgc tcctgcgctg cttggagacg cttggcattg
     7861 gtctcaagat gacgagccac cccctgataa gctgtcgcaa agcgttttat ggtgttgagc
     7921 tgtcctatat ccccaacctg atagctccca gcccgcttgg gcttactgct gtactctgct
     7981 atcaaggcct tggtcgaagc caaaagctcc ttgaaggcgg ccaagtcctg actggcatga
     8041 ttgctttcgt attgaatgat ggcctcgtcc aagcgatgga tatcagtgat cagctcacta
     8101 taatccacta ctgtcttggc atgactgaca ccagagtagt gaaccaggtc tgataactta
     8161 gctctggtat tctgtagtag ctcaagctga tccttgaggt gggcctgcga gagccgaagc
     8221 tctgactgca gggtcttaaa gacctgaccg ggtaactggg catgactatt actgtctatc
     8281 tggtaatagc cgtccttata cagcaagagg ctagctgagt aatcattcat caggctttgc
     8341 agggtttgta aaagtgtccc atgcacctca ctcagatagc tcttgattga gctagcggtc
     8401 tgaccctgaa ggcgactgtc tccaatcaag gctgacaggg cggtctggat actcgttatc
     8461 ccatctcccc aagcactgat cgtggtttgg gtgctttgtt gaagggaggt aatctcatca
     8521 tatttgatat tatagctcat ttcttcccct aacgttttca atgcgatatc aaaatgtttc
     8581 accaataata gcaatacatt tctttaatat acctctttta ttatatcaaa aaaaacttaa
     8641 tgattatcac accaagctaa gagcattgat gggtaataac atatagctta tccaaccttg
     8701 ttagcaggag tattacaaat aatgtattgc caagaggaaa agctgatata aataggtggg
     8761 acaaacgtgg tcaagaaaac ctttaacacc aagaaaacca tgataattct tgataacatc
     8821 aaatagtgcc tcagctaaat gattatgatg acctttacca aatcattctt tattatctgc
     8881 aagaaaagaa cagtgacatc tcttcgatcc gattacgaat ataaatcaag cttcaaaacc
     8941 gctcttagta cctttattcg ttgccaaaaa tatctcattg aactctctta ttcaaacgct
     9001 aagctagaag caaccaataa actgagcaaa aacataaagc ggcaagcttt ggctttagga
     9061 acttcaaagc taagattccc aatactttta acatcacaaa agagagcacc aagctggtcc
     9121 tctctagata ttagttatta gtcaccccac tacagttgac attgagcctc tttgatgaca
     9181 ctagtcgtga attagtgaga caacaacata gcgattaggg tcgttgccct ctgaatagct
     9241 ctcaacccca tcaatagcag aaactgtttt atgaacaatc tttcgctcgc tgttactcat
     9301 aggatccatg gtataatctt gaccagactc aagcacacgc ttggatacct ttttggtaaa
     9361 gtcaatcagg gtttctgtcc gatgctctac ataatcatga acattcaagg agacagaaaa
     9421 attcttagaa tagcggtcat gtaagaaatt ttgggccagc aattgcagtg atttcaaaac
     9481 cttaccatga tagccaataa cacgacctgc ctctggtgtc tctatctgaa gattgatctg
     9541 acgacgattg ttggtcctct caatagaggc ttcaatatcc atctcataga taatcttggt
     9601 cacatagtca gaaatctcct gtgcagctag ctcaatatcc ttactcatgt ccgctgcagc
     9661 tggatccagc tgactcgcac cagcagctga cgacacaggc tgtgcctttg actgagtagg
     9721 agctgactga gctgtgctta atggacctgt tggctgatga gcatcagact cagcagccct
     9781 tctgtcttgt gatcgaacag ccttcatctc ctcaagctcc acctcatcgg ggttaataac
     9841 cggtgcattt tgacggttga tctcctctgg aacactacgt acggcttttt tatcagcctt
     9901 atagactgtt ttttcattaa tgccttcaat atcaacctga gctggctttt taccaaagcc
     9961 caaaaagccc tttttctcct ttgaaatcac cttgatgtgt gcttttagac gtgacaaccc
    10021 caactcttga agtccttttt caattgcttc ttcaacagtc ttacctgtaa acaataccat
    10081 atcctaaact cctattttct tttcattgct ctcttacgag cgcgacgttc cttagctcga
    10141 cgctcttttt cttcatctgc taaacgttgc ctttcggcaa taaccttaaa gggattatta
    10201 aacagcaaga gctgaacaac ctgaaaggca ttggaaactg cccaataaag caccacacca
    10261 ctggccagat taaagcccat aaagaagatg aacacaggca tcacgtaggt catgatcgtt
    10321 atcatggccg tcttttctct agccgctaga ttggttagcc atgttgataa aaaggtaaag
    10381 acagccgcta aaataggcag aataaagaga tgatcatgtc gcgccagctc aacccataaa
    10441 aaggtgcctt ctcttaagaa agccacacga gtcagagact gaaacaaggc aaacatcacc
    10501 ggcatctgaa tcagcaaggg caaaaggctc atgtaaggat tgacaccata ctttttgtac
    10561 agagcttgac tttcttcagc tagcttcata cgagttgctg tgtctttagc agcatatttt
    10621 ttttgcaggg cctttagctc tggttgaatg tcctgcattt tctgccctga cttgatttgc
    10681 atgttaaaca atggcagtaa aagcaagcga atcattatcg taaataggat aatcccaatc
    10741 ccagtcgatc catcaaagga caaccattgg atcgccttgg caaaaaaata aaccaattgc
    10801 tcccagctac tagatgattg tgctgtcacc tctccacgcc cacaggctac tagtagcaag
    10861 acaagcggca ctagggctgc tgttttaact ctttttttca atctcaaaac cttcctcaag
    10921 caattttgct agctttaaaa catgatgtaa attttgtttg actgcttgat aatctaattc
    10981 ctctgcacct ctcctagcaa taacaacgaa atcctcagac ttgaggtgat cacccagctc
    11041 cattaaaaca tgtcgtatct tgcgctttac cgcatttcga gtaacagcat ttcctagctt
    11101 tttgccaaca gaaatccctg ctcgaaaatg cttgtgctcc cctttcaaat ggtaaatgac
    11161 aaattttcga tttgccatgc tctgaccaag cttaaaaatc gcctggaaat ctttctctcg
    11221 cttgacacga tagcttttct tcaaaactta actcccatat ctaaattatt accattatac
    11281 cataaaacat taaaaagcct caacccttat caatgggcct ataataagag attggaccca
    11341 ctatctaaag gatcagaaca aaaaatgctt ttagtgaatc acggtagctg tcaagtcttg
    11401 atagccttat caatcatact agcaaagaaa caaaaaaata aagcccggta aaccgagctt
    11461 tatctccgct gacttgagca tcagcaaata tgatatccaa acaaagacaa ctgaaacaat
    11521 cattttaata acaagcagcc atatcaaaaa tactatttgt ttatggagag agagagaaaa
    11581 caatattttg attgaattgg ggatggacca ctccattacc taatgatttc gtaaatcttt
    11641 attcatacta gacattatag cgaaaaatca ctaaaaaaga tgacaatttc ctgaaatgtt
    11701 catttttcgt cctaaaatgt cattcaactt aatttttagc gaaaagactt ccacttttca
    11761 aaaagctgtt tcattctcaa acgagagacc atacaagaat caccattttc aaaatacacc
    11821 aattgcttag ccttatcaat tcgaacaaca ttgtcaagat tgaccaagta agaacggtgg
    11881 cataaaaaca gcttaggagc taccgcatga atctcagata agttcccata aaattctaag
    11941 cgctctgttt gcgtccacag gcacaccttg tgaggcgttg ttgcagttgc aaaataaaga
    12001 atgtccttat aaggcagctt taggcgggtc tgcggggtct caaacaaaaa catctcttct
    12061 acttgacgac tcgacatcat ctcataggtg tagcgaatac attcctcaat gcgctcttta
    12121 aattgctgac tatcaaccgc tttatcaata aaatccaagg cagacacctt gtacctaaag
    12181 gaaatagggg cgaactctga atgcgtcgtg acaaaaacaa gcacagcatt gggatccttc
    12241 tggcgaatat ctgaggctag ctctagccca cttcttgatt tgtcaccaat ttcaatatct
    12301 aaaaaataca gctgatgatc tcctctctcc tgaatgctat caaacagctt ttgaggattt
    12361 gaaaacacct ctaattgatt atgaggaatc ctaccctctt ctaatatgga cgccacaatg
    12421 gcctcaatac gactttgttg aatcagattg tcttccagaa taaaaatgtt tagcatggct
    12481 tatctcattt ctaacaattg tctcaaacgg tagtgatcac ttttggttga aaaggtgatg
    12541 tggggatagc gctctaacac agccgagaac tgtagcaggc gcttatgagc atggcttcct
    12601 agctccaatc ggctagcatc aaattgcttg gcaatatcaa cccgcttgag ccttgtacta
    12661 ttttcaatga taaaaaatcg cttgccatct tgattaaaat aggcaatgga taaaaaagga
    12721 cgagagctgc ctttagctga caaaatagca ttatcaataa ctaccttgaa aagaacgatg
    12781 acatctaaca gcctgacaga agagctagca agcgtttcag gaatatcgat gtaaacagca
    12841 atgccctgca gctttgcttc taatagcttg gcatgcaata ggctgcgaat caccgaatcc
    12901 tgaacattat caagggctga taattcaggt gttagctgcc tgatagagct tgctgattct
    12961 tggataactg tttgatagac cttagaaata gcagctatat ctccactatc aatactatcc
    13021 tttagactaa ttagaatatt ttctgaatca tgcttaatag ccctgatctc acgacaaagc
    13081 cgctcaatat actgattgtg cttttcaagg taagcaacac gctccttttg tgccagagcc
    13141 aatctttgag atagctgatc cttagcaaag cggtccagct tgacaatgac ccagatgagc
    13201 agcatgaggt aaagaaaaat catgacagag cggtaacgaa aataaatctt gaaaaaatct
    13261 ccttggatat tgatcatgca gtgaaccatc acatagtaga aaagtaaggc tgcattcatc
    13321 caaaagaccc acttctttag cttgtcctca ctgataaact taatcaaggt caaatcaacg
    13381 ctaaaaatat agctaaacag gtaaaaggcc ggcaaaacca atgcatgaca gaccatcaat
    13441 agacctatgt cattattgat ttgatgaatg ctgtagccta aaaccgctgg caaaaggaaa
    13501 gagccaataa tacgaaagag cagctcaaca atcataatcg caaacaagcc attaaacaga
    13561 tgctcagaag cctttttatg aggtgcaaag ccaacactga cagcaacaaa caccagctga
    13621 tcaactagca gcacatgatc cagcagcaga ttagcaacaa caaagcaggt accaaccaaa
    13681 agcaatgatc taacagctag cttaatgcct gaaaatgtcg aaaagatgac ccagctattc
    13741 acaaagatca gagcataaaa gaatgacata cctagcataa aataaaactc tactctttct
    13801 ctatttttgg catgattagg gtctgactaa actgataatc atgactcctg gtgcgcaagg
    13861 atagctcagg atatttctgc aaaatccgct tggcattaga caagcctatc cctcgaccgc
    13921 tcccctttga ggaatagccc tcttcaaaaa tcctactaat catgaccctt tcgtccttgg
    13981 tcgtattggt tacggtgaaa atctgctgat catcagataa aaagtaggct atcgccactg
    14041 ctggctgggc tgtctctaga gcagcctcaa tagcattgtc acaaaaaata gatacaagca
    14101 gcaataaatc aagctctgag atatagctat cccgaatccg atctggaact tctaggctta
    14161 aggcgattcc tgccttctca gccttaatga tttttgatga tagcaagctt tttatcgagg
    14221 atacactgat tttactgagc tttgaaatat tgtaatgctt atcgtcccaa taatccgtcg
    14281 cctcatctac cgtttgggca tagacagtct gtacatctga cacagagcca gagtcaatag
    14341 cctgccccag cctttctagc ctcttgaggt aaactagctg aaatacctta acacccttat
    14401 aaagcttttc tagatgcttt ccataggttt ccagattagc aatataagcc tgctgttcct
    14461 tttttaattc ctgttttaag aattcctttg attgatgatt aaaataagac agtaaataaa
    14521 tcaacaatag ggtaaagatg agaaacagca ccttataaga cgttgacatc attatcgggg
    14581 atttaaggtc aagaaaggga tcagtaaatc ctaaaatcat aaagagatca atatagtagg
    14641 ccaaactaaa gagcaaaaac aagctataaa agctactggc cttatcaaac ctgtcagctt
    14701 taacaatctg cttgtaatcc tttcccacaa aataattaat caaagcaaag cttgggaaaa
    14761 tcatcacata agcaataaag tctaggacaa ggtgtctgac atagctgcca ttaactgaaa
    14821 aaatataggg aagtacaatc gctaaaataa agcgtgataa caaatcaaca aacactccgg
    14881 gaacaaaggc caagaataga gcctttaagc taaagcaggg ccgcttttct aaggctaata
    14941 cagctagcag caataaagga tcaattatca agggcggcaa taaagcaaac tgattcaaaa
    15001 agagagctgc tgtcaggaca aaaatctgct tccaaagtgc cagtttaatg tctgataaaa
    15061 aggaaaaaat actaatttct gtcacataat aaatcatcag tgatagtaat aaaaagagat
    15121 aataaatatc agtcattctg cctccttacc aactttatta ttttaacaca ctttgtgtca
    15181 atccctatta tatgaatttt ttatataatt cagcaagcgc aaaaacagtc catagctggt
    15241 ttgtgacagc gtttgcaaat cagatgtcaa tcattaaagc aaattaaaat atctgaccag
    15301 ccttacctta tctagggaaa aatattgtat aacaaataat ctaagaaaac cagtgacaat
    15361 ttaatattta ttttaataat atcttccacg ctcatcaaaa attaagcaga taagcctgct
    15421 ggattatgac atctagctat gcgctactgg gcgtcgtgtc gctagctcaa gcacactaaa
    15481 aaagaatgaa gcaaacatca gatatctcat ctctgcttca ttcatgatgt tatttatgat
    15541 catcgtccag cctagaccaa actactagct gcgatagtgt ttaaagcata ttggcaatat
    15601 gctcaatcga ttgttcacgt ccaaggaggt aaatggtatt tggcagctct gggccatgca
    15661 tttctccaga aacagcaata cgaattggca taaagaggtt cttgccctta atgccggttt
    15721 ctttttggac agccttgatt tgtgggaaaa tgttttctgg cttaaagtcc tcatctgaca
    15781 tcgcctctag cttttccttg aaggccttca gaactgttgg aacagtctca gctgccatca
    15841 cttctttttc ttttgcggtc agctctggga aatctgagaa aaataaatca gtcaatggaa
    15901 caatctcatc agcagagctt aattgaggct gatagagctc aactagcttc tctgcttttt
    15961 cagtcaagcg gcctgctgct tcaagaaatg gcttacaaag cgcatataca gcgccaagat
    16021 cagcatgctt aaagtactca ttgctcatcc agtccatttt tttctgatca aaggctgctg
    16081 gcgacttgct aagacgaatc tcatcaaata aggcaatcaa ttgctcacga gaaaagatct
    16141 cagcctcccc gccaggattc cagcctaaaa gggcaataaa attaaagact gcctctggca
    16201 tatagccttt tttgcggtaa tcctcaataa actgcagggt attggtatca cgctttgata
    16261 gctttttacc tgtctcagaa ttaatgataa gggtcatatg accaaagacg ggtgcttccc
    16321 agccaagcgc ctcgtaaacc atcaactgct ttggcgtatt ggcaatatgg tcatctccgc
    16381 ggataacgtg tgagatttgc atatcgtgat catcaataac aacagcaaaa ttgtaggttg
    16441 gatagccgtc ttttttctgg attacccagt caccaccgac attgccaccc tcaaatacga
    16501 tatcgccttt taccatgtct gtccatttgt aaacaccagc ctcattgacc gctaaacgaa
    16561 ccgtaggcac aatacctgct gcttcacgct ctgcaatata ggccgccttt tcatatgctg
    16621 acatgccaag gtattcattg acatagcgag gtgtttcacc agctgcctct tgacgctcac
    16681 gctctgctgc cagctcctcc tcagtcacat aagacttgta agccttgcct tctgccaata
    16741 attggtcaat gtattgttga taaagggcta gacgctctga ctgacgataa cgctcgtgcg
    16801 tctcaggact ttcgtcccaa tctataccaa gccattttaa attttccagc tgagaacgct
    16861 cgccgtcctc gacatgacgc ttacgatcag tatcttcaat acgaataata aagtcaccgc
    16921 catgatgacg agcataaaga tagttaaaga gcgctgtccg cgcatttccg atatgtaaaa
    16981 ggcctgttgg gcttggtgca tagcgcacac gaattggttt agacattctt tttctcctat
    17041 ggtttcattg aaagaaggga tcctgggcta taaaccgttc ctacggtagg cttgctctat
    17101 gagaaaatgg tcgataagga acaaaaatac agctaatccc ttggaaatct aaagatttca
    17161 atcgctccta ttatagcaca acttcaagca ttgggcgaca aaaatcaact tagaacagct
    17221 gcataacgaa aatgcatgta accattttct agctacatgc attgttttca tctacttctg
    17281 atattttgat atcatcagct gttcacattc agcttaattg tagcctgaat tgatttgaaa
    17341 aagaccatac cactgatgag aaaatcgcta tcaaaaacgt aaagatcctt atgcgtttgg
    17401 cgtggcctag agctaggata gctctataag cagctcattg gcaagcagtg ctgcctcttt
    17461 caatagcttc atagcatgcc tagctataga tattagtcag gctattgacc tgcattgatg
    17521 tcaagctaca ccccagcaaa gaaagcgaca atatactctg gcaaccacga acctgtcata
    17581 tccatttcaa tccatcaatt ggcaaggctt ggtttacttc caactgctta atggccgcct
    17641 gtgacaatat agctctgtaa aactccagca aattgctgaa ggttcaggct ttgcacatag
    17701 acatctccgt atccgctaaa ggtattgacc actccctcac ctgtaccaat agactgcata
    17761 aagccatttt ccaaatgaat atcataatcc aaatcctgac tccaagccac cacatggcta
    17821 ttatcaatcg tcatgctgtc gccatgaagc gtgatttttt taatcgaacc aaaagcattg
    17881 accaataggg ttccttctcc ttgtgttgac atcacaaaga agccaccctg accgctaaat
    17941 aaggccttac caagtttttg gcgcttcatg gtgtagtgag ctgagccatc taaagccaag
    18001 aaggctccgt cattcaaacg gtattgatct acccctagct caagagcaat aacctgacca
    18061 ggcattgaag gggcaagcgc tagcttgcca ctaacatcat tagcaatcgc ctgtgtgata
    18121 aacatggatt ctcctgaaac cattgaacgg ccaatggcac caaccagctt gccaagacct
    18181 gagccacgcc cattgagctt ggtgtttaag ctgattgacg gtgtgtggta aaccatactg
    18241 cctttttgta gaaagacaga ctcccccatg tccaaatcaa tttcaacaag aggaaactgc
    18301 atgctgctgt caatagtata ggtcattcga ttataggcca taacaccact cctttgtatg
    18361 attttgttga tacaatcaag tatagtcttt tttggcagca ttgtccacta gctactgtcg
    18421 ccgccattcc taaccagtct caaagccata ctacaaaccg atcagctgtc aggatttcgg
    18481 catcgccacc tgagacatac gtccagtggc aacatcatag accgcaccac taatgaccac
    18541 gtcttttgga atcaacggtg attgctgcaa tatagccata tcctcacgaa cacttgcttc
    18601 cacatcagta aaggggagaa aatcacagtc agacacatct actcccagag tatcatgaag
    18661 ctgcgctgta aaggcttcat tggtaaaggt ttgcgcccca caatccgtat gatgaagaac
    18721 aacgatctca cgcgttccca gctgctgctg cgaaatcaca agagaccgaa gcatgtcatc
    18781 tgttatccgt ccaccagcat tgcgtaaaat atgggcatca ccaagcgcta aacccaaggc
    18841 ctgcgccaca tgcagtcttg agtccataca ggtcacaata gctaccttag ttttgggctt
    18901 taggggcaaa tgagcagtcc catgtaaggc gacataggct tcattggcag ataaaaagcg
    18961 ttcaaaatat gacatgaata cggtcctccc agactaatct ctaagctatc tcagccttga
    19021 gctgtctgtc tatcttatca tcttttgcct gaaatgtctg aatgctgaac tgctttttaa
    19081 cacaagcaga tagcactagc ctaactgaaa ccagaggtag gtgagccagc cttgacattg
    19141 gaagcaagct tagcagcccg ccctttgagc cgctaaagta agggcagcaa gaacgtgaca
    19201 aaatcagtta attgtcattt taattaaaaa acgaaactac ggagacaaac tgataaattg
    19261 ctatttctcg ctatcagcca gtatgctaaa ctcttctcag aaggccttgg cagtcgctag
    19321 ctgctaagcc aataatacta aattaaggag aatagcaatg aaacaaacaa aaataatctg
    19381 cttattggct gctgctgctg tcctaaccct aggtcctatc agcacaggcc agacacaacc
    19441 acagaccgta tatgccagtc aggttagtgg agacagctgt atcgatctag gtaatggatg
    19501 gtttaaatgt cctaaggata ttggaggatg ggacattctt tttaatcaag attaccaagc
    19561 gccttcacga tcgccatttt tcacttggat ttcaggctgg tttaacttta tatggcagtg
    19621 gtttaaaagc ttctaagatc tactaatacg ctatccatat cataaggctc ttagaggcta
    19681 gctctctaag ggctttttgg ttctacggaa cactataagg accttccaat actactggtc
    19741 ttaaaataaa aaagactagg aatagctccc ctagtcctca tgttaaaaac aacaacctaa
    19801 gtaaagacag cctttaagac ctctcctact gtcgtcacac caacaacctc aatccctttt
    19861 ggcagatcaa tcccctgcaa tgagcttttc ggagcgtaaa gcttggtaaa gccaagctta
    19921 gcggcttcat taatccgctg ctcaatacgg gtcacacgcc gaatatcacc agtcaagcca
    19981 atctctccta aaaaggcctc ctgagggttg gttggttttt ccttgtagct agaggcaatg
    20041 gccacagcaa ctgccaagtc aatagcaggc tcatctagct tcacaccgcc tgctgacttg
    20101 aggtaggcat cttgattttg tagcagcagc ccacatcgct tttccaagac agccataatc
    20161 agactgacgc gattaaagtc caacccagtt gtcgttcgtc tagcattacc aaaaacagtc
    20221 ggtgtcacca aggcctgcac ctcagctaaa atcggtctgc tcccctccat ggtgacaacc
    20281 acagcagagc ctgttgcgcc gtctaatcgt tcctctaaga acacctgact gggattgagg
    20341 acctccacta gcccacctga ttgcatgtca aaaataccaa tctcattggt tgagccaaaa
    20401 cgatttttaa ccgctcgcaa gatacgaaag gtatgatgcc tctcaccctc aaaataaagg
    20461 accgtatcaa ccatatgctc cagcatgcga ggccctgcta gggtgccctc cttggtgaca
    20521 tgtcctacaa taaaggttgc aatatgatta gacttagcta gctggagcag ctcagcagtg
    20581 acctctcgaa cctgactgac cgagccctga acacccgaaa tctccggact catgatcgtc
    20641 tgaatagaat caataatcaa aaaatccggc tgaatggctt caatctctgc tcgaatagcc
    20701 tgcatattgg tctccgcata gaggtaaaaa tcattgtcgg tctgtcccaa acgatcactg
    20761 cgcatcttga tctgctctgc cgattcctct ccagagacat ataaaacagt tcccttatcc
    20821 gcaagctgga tagaaacctg caagagcagc gttgacttac caataccagg atcaccacca
    20881 atcaaaacca agctccccgg cacaacacca ccgcccagca cacgattgaa ctcattcatc
    20941 tctgtctgga tacgctggta gcgaacgcca ttgatatgct ttagcttgat gggcttactt
    21001 ttttctccag tcaggctaat acgggcattt ttgacgtcct tgacctctgt ctcctctaca
    21061 aaggaagacc aggcagagca attagggcag cgccccagat atttgggtga ctgatagcca
    21121 cattctccac agataaacct cgcctttttc ttagctataa cacatttcct ccttgaatct
    21181 aagcatcaac tggctacaag cacgtgaagc agcctgctaa taccttatcc tcctgtcgaa
    21241 ccaaaaccac ctgtccgctc accaccagcc tgatcaccat cagcaatcaa aaaaggcata
    21301 aatacgccct gaacaatgcg ctcaccagct gacaaggtaa tggtttgatc cgtaatattt
    21361 ttcatctgag caaaaatatg cccttcattc gcagggttac catagtagtc accatcaata
    21421 acacccacag aattgatcag aaccagtccc tttttacgag gattgctgga gcgatcatag
    21481 agataaagca cctcaccgtc ttgcatatac gccttgaccc ctgttggcac aagtacaatc
    21541 tcacctggtg caatgctggt ctcctctgca acagataagt catagcctgc tgcatgagct
    21601 gtctcacgtt ttggtaataa atcagtatca gtaaagcctg acacaagctc aaagcctcga
    21661 atccttgtca tgattaacct caagagccct tgtcagtgcc tgcagcagct gtaaaatcac
    21721 ctgccaggac agcagacaaa agcactctta tcccttttct ttttttagtc ctcttattat
    21781 aaaatattcg taaaggaata gcaaaaaagt aggggctgca ccccaaaaat caccgactgc
    21841 ccccctctat aacgcaacaa aatgcaagag ggctaaatct ccttgccggc atagctaaac
    21901 cgaatccttg gaaaatcagc ctccaaatcc ttatctgcca taaaagcctt ggcgtccttt
    21961 ttcacctgaa ccagatcaat cccttgtatg tttgcagcat agacgcagcc gcaatagcac
    22021 tggcggtaaa tatcatattc ctcacacatt tcgaccgacc tgcgatagcc attatttttc
    22081 ttgaaatcac taggcaaata cttagtggtg taaacctttt gcacatcaat gcctacatcg
    22141 ttaatcgtct gtgagttttt atgagggctg atggtcaagg cactagcaaa ataatcaaag
    22201 cccagctcca cagccttttg tgccgtcttg tccaagcgat aatcaaagca aacacgacaa
    22261 cgatccccgc cctcagactc tttctccaag cctcggacag tcttgacaaa ttcatttggc
    22321 acataatctg cctcgataaa ctgcacgcta ttacctgttt tatcgttgaa ctctgctaca
    22381 aatttctgag taacataggc cctgcggtgg tattcgtcct ttgggtgaat atttgaatta
    22441 gcaaaataaa ccgtaatatc agcgtactgg gttaaatatt ccagcgtgta ggttgagcag
    22501 ggagcacagc aaacatgcat caaaatgcga ggacgtatag actccctcgc ccagaccttg
    22561 gtcatctgct gcatgacccg atcatagttt attttctggt ttggattcat tctagctaga
    22621 atctcttgta agtcaatcat tacatcttct accttctatt gtctgtctct tttattatag
    22681 cacattgcct tgacatgctt tgcatcaaaa aactccgcca aagcggagtc gatcggcaaa
    22741 agctgttttg atggttttta agaataacaa cagcagctta tgtaatgatc atttttagaa
    22801 gctactcaaa cacaaactga ttgtgataaa gctcggcata aaagcccttt tgccttagca
    22861 gctcatggtg acttccctgc tcaataacct taccgtcctt tagaacgatg atttcatcag
    22921 catttaaaat ggtttttagg cggtgggcaa tcacgaagct tgtgcgacct gccacgatag
    22981 cctccatagc cttttgaatc ttactttcag taacagtatc aacatttgat gttgcctcgt
    23041 ccaaaatcaa gacctgagga tcggttaaca gcgtacgagc aattgaaata agctgctttt
    23101 gaccagttga aaagacattc tcatcatctg acacctgagt ttggtagcca tcaggcaagg
    23161 acatgataaa ctcatgaata tgcgttgcac gcgctgctgt ctcaacctct ttttggctga
    23221 ttgtctgatt accaaagcgg atattatcag caatagtccc agaaaacaag actgactcct
    23281 gtaggacaat accaacccgc tgacgcagac tatccaagtc atattcccta atatcacgac
    23341 catcaaaggt aatagagcca gcatcaacat cataaaaacg attaatcaga ttcatgatcg
    23401 tggtcttgcc agaccctgtc ggtccaacaa cagcaaccat tttccccttt ggagctgaaa
    23461 tcgacacatc tgacagaatt ttttgtcccg gcagataacc aaagtcaaca tgcttaatct
    23521 caaccccttc ttttaatgct gtaaagacag gagcatgctc agggcgaacc tcttcttttt
    23581 catcgaacat ttcttggata cgaccagcac ctgtaaaggc cagctgcaat tcaccccagc
    23641 tagaggcaat ctgcataatc ggttgataat actgctgtga atactgaaca aaggtcacca
    23701 ccaagccaag agcagcagct gttgacatgg acttgtcacc aaggacaatg gttgagccag
    23761 caaagatgac aatagctgta ttcaaaagac tcatcccatt catcacagga aacagcagac
    23821 cagcaaaaag gcgtccctta aaggttgctg cacgcaccct ctcattgtgc tcaataaagc
    23881 catcaatagc atcctgttgc accccttgaa caataatagc cttctggcca gaaatcttct
    23941 cgtccatgta agcatttaaa gcactgacct ccttttgctg caaatcagta tatttgcggg
    24001 ccattgtaat gatgacaacg agaagaataa gcgccacagg ggttgaggct atcgttacca
    24061 aggccaagcg actatcctgc ctaaacatca tcagcactag accaatatac aaagcaatat
    24121 ttgtcaagac ctgaatcaga gattggttca tggagttttg aatattatca agatcactgg
    24181 taaagcgtga tagaatagca ccgtccttgt gactatcaaa aaagccaact gtcaagcgct
    24241 ccaatttgcc aaataagccc ttacgcatgc gattggtcga atgcgaaata acccttgtaa
    24301 agaggagact ataaataaga ttagccactg ctgtaaagag ataagccaac aatagctttc
    24361 ccataaccgt cctaaaaggc gccatagagg gctcaactaa gggctgaccc gtcattttgc
    24421 taagcgcctg agccttgtaa tagcgctgca cccattctcc cagctcagct agagagtctc
    24481 ccaaaaagac aggggcctta acctgcaggt aggttgccag gacaatagca aagaatatca
    24541 caacaaaaga gagcttataa cgtttaaaat aaaaccagaa aaatcgcagg atcttcatta
    24601 gttctcctct cttccctttt gagtttcgta aatttcacga taaatcggat tggaagcaac
    24661 cagctcagca tgcgtccctt ctccaatcaa tcgaccatta tcaagaacaa gaatcttatc
    24721 tgccttgaca actgacgata ttttttgtgc gatgatgact gttgttgtct ctttgagctc
    24781 cttattcaag gcctcctgaa caagcttttc agatttggca tctagagctg atgtcgaatc
    24841 atcaagcacc aaaatcttag gattgttaat cacaccacga gcaattgaca ttctctgctt
    24901 ttgaccgcca gaaaaattat tgccacgctc ttctacctca ctctggtagc cagcgtccat
    24961 acggtcgata aattccttgg cctgcgcaat gcgtgctgca ttttctaaag ccaattggtc
    25021 agcataggga ttgccctgac gcagattatc cgcaatagtc ccagaaaaaa gaatagcctt
    25081 ttgcagcaca atagagacgg tgtcgcgcag agtctcttga ctgatgcttg gcagagcctt
    25141 accaccaatc aggatttgcc cttcctgtgg gtcaaacaaa cgcggaatca gctgcgcaag
    25201 ggtcgacttg ccagcacctg tcgcaccgac aataccaacc atttgaccgg gctcaacctc
    25261 aaacgaaata tgctttagag tggcttcact gtcatttgga taggtaaagc tcacatcatc
    25321 aaagacaata ctgcctgtca gctcctcctg ctcatggtta acaaaggtca tagcaggctc
    25381 tgtttctaaa atctccctga tccgaccaat cgaggtcaag gcacgacttg cctgcattcc
    25441 cataaaacca accatcgtga tcgcaaagct gatttgtccc atataggtca taaaggaagc
    25501 catatttcca ataacagcag gatctgtttt gaccagccct gaaaccagat acaaggacaa
    25561 ataaatggcc atgtaagaca ccaacatcaa aataggctgc atgattgaaa agccatagcc
    25621 gataaacaaa ttcaagccca gtaggtcatt tgaagcctcc ttaaatgtgt catactggct
    25681 tttttcctga acaaaggact tgaccacacg cacaccgcgt aggttttcct tagcaatctg
    25741 attgatccta tccatcaagc gctggaagat cccaaagcga ggacccatct ggctcatcac
    25801 cagcccaatg actaccattg tcatcacaac cacaagcacc aagacccacc aaaggctcgg
    25861 taaggcctgc accgctaaaa taaaggcacc gacaaataaa atcggcaagc gcaacaatat
    25921 ctgaaaaagc atcatcacaa agttttggat ttgattaata tcatttgtca ttctaacgac
    25981 aagatttcca gcattgaagg cttccacatt ggcataagaa aaggattgga tctttctaaa
    26041 ggtctgctca cgaatatcag cagatacccc ttgagcaatc ttggcagaca agatggtatt
    26101 gaccgcacct gacaccaagc caatccctgc tatcactaac agccaaaaac ccacctctgc
    26161 aatccttgtc tgatcatttt ccataatagc agctagaaca tctttgaggt aatgtggctg
    26221 gagcagggca ctggctacga ccccagaaat catcactagg gacagagccg cataccattt
    26281 atacttcatc acagcatttc taagcatctg tatctccttt ataagctcgt atattttgtt
    26341 tcagctgatc gataaccttt tttaccgtca gcagctcttc tcttgaaatt tccttgaaaa
    26401 aatagcgctc aatatctctg cggcactcct ttaataccgg cagcttagcc ctaccagccg
    26461 aggtcaagac aacctgcttg cagcgcttat ctgtagccga ggcaacaact cgaataaagc
    26521 catttttttc catacgcttc accagattac tcgtaaccga ttttgagatt tgaagctcct
    26581 tttcaatgtc cttgacaaaa atgtctctgt cttgatggca atgcaaaaag acaagaacat
    26641 gcccttgtgg accagcaaga tgctggaggt catacttttt agcaatctct tcgctaattt
    26701 gctcaacctg atgggtcaat tcacgaagct cagcaatgat tcttggcatt tccttcctcc
    26761 ttagttctca tgataaccat tttagttctc ttgggaacta ttgtcaacca aaaaggctta
    26821 cgatctgact atcttccctg ctacttaccc tttgctagca ccactgagct gacaggctag
    26881 gccagcagac cttttctatt agagttaggc cttgtcttat gatataataa ggtgattagc
    26941 tcttaaagga gaataaaaat gccaaaacaa aaggtagcca ttttgggacc tggctcttgg
    27001 ggcacagccc tggcacaggt cctaaatgac aacggacatg aggtccgact atggggaaat
    27061 atccctgaac aaatcaacga aatcaacaca cgccatacta atagtcatta ttttaaggac
    27121 attgtcctag atgaagccat caaggcaacc cttgatttga aggaagcatt ggctgatatt
    27181 gatgctatat tgtttgttgt gcctaccaag gtgactcggc ttgttgccaa gcaggtcgct
    27241 caggtcctag accacaaggc tattgtcatg cacgcctcaa agggattaga gcctggaacc
    27301 catgagcgcc tctcaacgat cctcgaagag gagatccctg cccagctgcg cagtgaggtc
    27361 gtggttgtgt ctgggcctag ccatgccgag gagaccatcg ttcgtgacat taccctaatc
    27421 actgcagcct caaaggacat cacagctgct aggtatgttc agaccctctt tagcaaccac
    27481 tacttccgtc tctacaccaa tactgatgtg atcggtgttg aaaccgctgg cgctctcaag
    27541 aacatcattg ctgttggagc cggtgctctg catggccttg gctatggtga caatgccaag
    27601 gctgctgtca tcacacgcgg tcttgcggaa atcacacgac taggggtcaa gcttggggca
    27661 gaccctctga cctatagcgg cctatctggt gttggtgatt tgattgtcac aggaacatct
    27721 gtgcattcac gcaactggcg agctggtgct gctcttggtc gcggcgaaaa gctcaaggac
    27781 atcgaaaaca atatgggcat ggtgattgaa ggcatttcca caaccaaggt agcctacgaa
    27841 attgcccaag agctaggggt ttatatgcca attaccagcg cgatttacaa atctatctat
    27901 gaaggtgctg acattaaaga aagcattctg ggcatgatgt caaatgaatt tcgctcagaa
    27961 aatgaatggc acacataagg aaccacaaat caaggaggaa ctcatgacaa aggtcagaaa
    28021 agccattatc cca
//
LOCUS       DARYLJ010000034        25286 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYLJ010000034 DARYLJ010000000
VERSION     DARYLJ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25286
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(122..1381)
                     /locus_tag="TU746_001319"
     CDS             complement(122..1381)
                     /locus_tag="TU746_001319"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL0891664.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(1697..2902)
                     /locus_tag="TU746_001320"
     CDS             complement(1697..2902)
                     /locus_tag="TU746_001320"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL0891665.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(3235..5454)
                     /locus_tag="TU746_001321"
     CDS             complement(3235..5454)
                     /locus_tag="TU746_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0891666.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            5981..6922
                     /locus_tag="TU746_001322"
     CDS             5981..6922
                     /locus_tag="TU746_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL0891667.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(6897..7100)
                     /locus_tag="TU746_001323"
     CDS             complement(6897..7100)
                     /locus_tag="TU746_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL0891668.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(7481..9157)
                     /gene="dnaX"
                     /locus_tag="TU746_001324"
     CDS             complement(7481..9157)
                     /gene="dnaX"
                     /locus_tag="TU746_001324"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL0891669.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(9157..9654)
                     /locus_tag="TU746_001325"
     CDS             complement(9157..9654)
                     /locus_tag="TU746_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL0891670.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            9834..10604
                     /locus_tag="TU746_001326"
     CDS             9834..10604
                     /locus_tag="TU746_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL0891671.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(10786..11058)
                     /locus_tag="TU746_001327"
     CDS             complement(10786..11058)
                     /locus_tag="TU746_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL0891672.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(11081..11707)
                     /gene="udk"
                     /locus_tag="TU746_001328"
     CDS             complement(11081..11707)
                     /gene="udk"
                     /locus_tag="TU746_001328"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL0891673.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            11803..12897
                     /locus_tag="TU746_001329"
     CDS             11803..12897
                     /locus_tag="TU746_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0891674.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(13162..14448)
                     /locus_tag="TU746_001330"
     CDS             complement(13162..14448)
                     /locus_tag="TU746_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL0891675.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            14870..16033
                     /locus_tag="TU746_001331"
     CDS             14870..16033
                     /locus_tag="TU746_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0891676.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(16156..18774)
                     /gene="alaS"
                     /locus_tag="TU746_001332"
     CDS             complement(16156..18774)
                     /gene="alaS"
                     /locus_tag="TU746_001332"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL0891677.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(19130..20131)
                     /gene="prsA"
                     /locus_tag="TU746_001333"
     CDS             complement(19130..20131)
                     /gene="prsA"
                     /locus_tag="TU746_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL0891678.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(20194..20901)
                     /locus_tag="TU746_001334"
     CDS             complement(20194..20901)
                     /locus_tag="TU746_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL0891679.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(20984..21622)
                     /locus_tag="TU746_001335"
     CDS             complement(20984..21622)
                     /locus_tag="TU746_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0891680.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(21672..22304)
                     /locus_tag="TU746_001336"
     CDS             complement(21672..22304)
                     /locus_tag="TU746_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0891681.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(22294..22851)
                     /locus_tag="TU746_001337"
     CDS             complement(22294..22851)
                     /locus_tag="TU746_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0891682.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(23050..24852)
                     /gene="pepF"
                     /locus_tag="TU746_001338"
     CDS             complement(23050..24852)
                     /gene="pepF"
                     /locus_tag="TU746_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL0891683.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(24842..>25286)
                     /locus_tag="TU746_001339"
     CDS             complement(24842..>25286)
                     /locus_tag="TU746_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL0891684.1"
                     /translation="MIHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMD
                     KHLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHE
                     DLSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT         7317 a         5880 c         4841 g         7248 t
ORIGIN      
        1 ggatagacag ggggttctta aaaatcaaaa gcccctaaaa ccactctcat accaagcagt
       61 cttaggagct ctaagcattc atgtcaggtg ataatcatta ggctatgaaa gccttcagtt
      121 cttaatcctc aataagctga atatcagccc ctaaggctgt tagcttatca ataatgttag
      181 catagccacg taaaataaac tcaatattgc taatctcggt tttaccctga gccattagac
      241 ctgcaatcac caaagcagca ccagcccgca aatcagttgc cttaacctgt gccccactga
      301 ggcgattaga gccatgataa acaatttggc tgccaagaat ggcaatatct gctcccatac
      361 gagcaagctc tggcacatgg ttgacacgct tttcatatat cgtatcaatg atactaccac
      421 gaccctcagt ccttaaaagc agaggagtca aaggctgctg taggtcagtg gcaaagcctg
      481 gatagggaga ggttttaata gtgactgctt tcaaggcttc ctgcttttcc acaaaaatag
      541 aatcctcttc aaccgtcatt ctcacaccca tttcctctag cttagcaata aagctctcta
      601 agtgctcgta aaggacattg gtaatcctta ccccactacc aacagcggct gccaaggcaa
      661 tataggtacc agcctcaatg cgatctggga tcacctgatg tctggtgcca tgaagccttt
      721 caactccctc aatcgtaatc acatcagtac ctgcaccacg aatatgcgcc cccatgttat
      781 ttaacagtgt cgcaacgtca ataatctcag gctctctagc tgcattttca ataatggtct
      841 taccctttgc ctttgtcgca gcaatcatag tattaatggt agcgcctaca ctgatagtat
      901 ccatgtagat atgagcgcca tgaagctgct gagcctctgt catcaggtgc atgcttgctc
      961 cctcataaga tatctgggcc cccattgctt caaaagcctt cagatgaaga tcaataggcc
     1021 tagggcctaa gtcacagcca cccggcaagc ccacaaccgc ctgcccaaag cgtcccaata
     1081 gactgccata aaaatagtaa gaggctctta ggctgttaat tttaccataa ggcataggaa
     1141 tatcttgaac ccctctgggg tcaatctcca aggtatcccc ctgataggtc accatagctc
     1201 ccatgagctt catgatttca ataagactgt caacatcact aatagctggt accccatcta
     1261 aagtgacaac atcgtctgcc aaaataatcg caggaatgag agctacaacg ctatttttag
     1321 cgcctgaaac tgccacctct ccggataagg cttttccacc attaataata atttttcgca
     1381 tactttcaaa actttctgat actagaattc aaccttttta ttttatcaca aatagcggtc
     1441 tattacaatc acctcatcac cagctgctgc aacaggctta acaacctgcc tcttgatcac
     1501 ttttcataac aggtttttga gaagccagac tcttatctgg atctttcttc tgctgcgcag
     1561 gcctttttgt ctttcatagc cgccaagcct gacaagtttt gctggactaa aaaagctccc
     1621 aaccagcagc acagccgcta gctcaggagc tattatacct ttaagtcaat catcaactaa
     1681 ccggcgctca atctgcttaa gcaccctctg acagtgctgc caccgcttct gtcaatggag
     1741 ataccttgtc caattgttcc caaggcaggt caatgtctgt tcgccccatg tgcccatagg
     1801 ctgctgtctg cctatagatt ggacgcttga gatcaagcat cttaatgatc cctgctgggc
     1861 gcaggtcaaa gacctgacga acagccgctt ccaaaatact ttctgacact gttgatgtcc
     1921 caaaggtatc cacacgaact gaaactggct gtgcaacccc gatagcatag gctaattgaa
     1981 cctctgcttt acttgcaagc cctgctgcca caaggttttt ggcaatataa cgagctgcat
     2041 aagaggctga gcggtcaacc ttagttgcgt ctttaccaga gaaggcacca ccaccatgac
     2101 gcgcatagcc accataggtg tcaacaatga tcttacgacc agtcaagcca gaatctccct
     2161 gaggaccacc aataacaaaa cgcccagtcg gattgataag gaatcttgtc ttctcatcta
     2221 gataatgggc tggaataaca gccttaatca cctgctcaat catatcttga cgaatctggt
     2281 cattgcttac ttctggatca tgctgggttg atataacaac tgtatcaaca cgaacaggct
     2341 tatcatgttc atcatattcg accgtaacct gtgatttagc gtctggacgc aaatagctga
     2401 tctcacctga ttttcgcagt gtcgccaaac ggcgtacaag ctggtgagat aaggaaatcg
     2461 gcagtggcat tagttctggt gtctcatcaa ttgcaaagcc aaacattagc ccctgatccc
     2521 cagcaccaat cgcattgaaa tcatcgcttt gtccttcacg tgcttcaagt gcttcattaa
     2581 cgccttgagc aatatctggt gactgctcaa ccagagatgg atgaacaccc actgattctg
     2641 ctgaaaagcc atattctgcc tcagtatagc caatctcagc gatggtatca cgaaccacac
     2701 gattaatatc cacataggca gttgttgaaa tttctccaaa aacgtggacc gagcctgtgt
     2761 aaacgcaggt ctctgcagca acgtgtgcct ctggatcctt ggctaaaata gcatctaaaa
     2821 tagcatctga aatttggtct gcaatcttat ctggatgccc ttcagatact gattcagacg
     2881 tgaaaagttt acgttctgac ataaaaatgt ccccccttaa aaagaatgat acccaccagc
     2941 acacatgcca gataggattt tcctagcctc actcatcaag ccagccgcca atacaaaagg
     3001 actgtatcca agctagccta tgactaacgc ttagcgagtt acaaagtacc ggcttttaga
     3061 ctgctatcct cagataacaa agccgtctta tcgggactta ataacttatc tattatacca
     3121 cttttagcgg gatttgtaag agctccatca gcttttttct caaaataaga aaaggaatac
     3181 cgctacaggc gtattcctcc tcttaatgtc gtgataatca gcgcaagcta tcgattaacc
     3241 atggtggtgc tcatcgtgat catgatgctc atggtcatgc ttatctgctg cctcttgatc
     3301 agtatcagcc ggcttatgct cgtcttcaac agcttctgct ggtgtggcat tatttagact
     3361 accaccctct gctgccttga agttcttgat aattccttgt gggaattgtc cgctttcagc
     3421 agctagctcc tcagctggga agtggttacc atcagcctga atgtatttca gggtttggtt
     3481 aggctccttc aaggccaagg tgttaatctt gttacgatta acattaattg cttctagggc
     3541 gagataattg ttgacaccct caaaattagt cagctggttc tcttcaaggt taagagactg
     3601 taatgagctt tgtgtacctg gtaaggccaa gctattaatc atgttctggt tagctgatag
     3661 ctgaatcagg ctcttattgt gctcaagacc tgtcaagctg ttaagcttgt tttggtcaac
     3721 cactagctgc tctaatgccg gtagatcctt gacaaagcta aggctttgta aattaacctc
     3781 cttggcagtg atttccttga gagcagagga ttttaaggtt gacaaatcaa ggtcagggtt
     3841 gtttgacaca aagagtttgg tcaattgtcc cttgtttgac aaggcactca agtccttaat
     3901 ctgattgtgc tctaggctga cagcgactag cttttgagca tttgccaagg cagaaagatc
     3961 tgtaatcttg ttaaagtcaa ggttaacgga ctctaggttt ggcaattctt tcaaaataga
     4021 aatatctgtg atatcatttc ctgctgccga aattaccttg taatgcggaa aggctttaag
     4081 gaagctcaaa tcagaaacac cattttgaga aatatcaatt ccttcaagcg ttggcaggtt
     4141 cttcaagaaa tcataatttt taatgccggt ctgtgtcatc cacaattgtt tgaggttctt
     4201 gaactggtag actggggtaa tatcagtgat tggggtaaag ccaataccta aaatctgtat
     4261 attaggcatc aggtttaaac ctgcccgctt aagaggatcc ttaatctcac cgatattgag
     4321 gtattcaaca gtcgccaacc atgccttcat tttctctagg tctcgctctc ttgatggaaa
     4381 ctcagttggt gcatttgcat ggataatgga cgaaatcact tcctcatcaa agccaagctt
     4441 tctcagagtt gccataccga ttctatcctt agcatgcgga tctactgcat gaggatcaaa
     4501 aggttttgat aaatcaatat cgtcaatata ggttgcatga cgatggtcac catgtggata
     4561 gtcaagaatg ataccttctt ctgtatgctc cacacgaatg ctgtcctcag gaatatttaa
     4621 tgacttagcc aaatatgctt ttttcaaagc aatcgttttc tcaagatcac tttgtggctt
     4681 agctggtgct tcttcctttg gctgttcgat taaatgcttc cacttgctgt tacgcaagct
     4741 ttcataagtg actaaatgat tgtggccatt gtgatcaaca atcaatccat atgatgttcg
     4801 accgacaata cctgtcccgt caaacaagaa gccatcactt gttgggtaat caacacctgc
     4861 aaattttcca gacggtgatg atggagctga tagtggcaca tggttaggca ctggataagc
     4921 tacctgacca cctagtgagc tttttaggat atagtggtaa tgatcaccat gacggacaat
     4981 atagcccaag gcgtcctcag ctacaatatc agctgggtta aacacatagt gatggtgcgg
     5041 gtcattagca ctagtatggt gatgacctga tgctgccttg gtctgctcag gcttgtttag
     5101 gtcagcgtcc tttggaatca ggtactcaaa cttgctgccc ttgagatctg cataaaaaat
     5161 aaaatgcgaa tgcccattat gctcaacaac aataccgttt tctgttctag ataagatttt
     5221 tgaatccttg gtcaagataa aaccgtcatc agttggaaag tcaatccccg ctactccctt
     5281 acggtctttt cttgtttgct taaccttttt agactgtttc tttttggtcg cttttttagc
     5341 tgtctgtttt gtcttaggct gatttgttgg ctgctttgtc gactgacaag ctgtcagggt
     5401 caggtgacaa gccataaaca ggctagccat tagcattaat tttttacttt tcatctttcc
     5461 tccataaatt aactggttaa ataagatatt aactagttaa atataccaaa aaaacaaata
     5521 atttcaactg ttttcttatt tttaattcat tctcattcaa caatcatagt agcttggcta
     5581 ggttggcaga aaaatgagcc tctcctactc tcatcaaata aacagatagc cttaatgatg
     5641 gctgagataa cagcatacaa agtcgttaaa gtcacttgta agaaaaagaa ggacatatct
     5701 taccaccact atcttgctca tcaaagccct acggctttca gacaaaatct tcataacagc
     5761 ggaaaggctg atgaagcagc tcagacaaaa agagcaagct ccttaacgtc aaggatcaga
     5821 gatcagcaca aaaataacag caggctacat taagaactgc aattccttga aatagaattg
     5881 cttttttaca aaaaaatcgt ctccctagac tgttccatca tctcacgtca tttgtattat
     5941 ttgctcttga aatccagtca ttttatacta tactagaatt atgaagacat ctgaaaaaat
     6001 ttaccaatta ctagcttgca gcgacgacta tgtcagtgga gaatacttgg cagagcagct
     6061 caagctttct agaacctctg tctggaaatc catcaaaagc cttgaaagtc aaggccttca
     6121 cattgaatcc ctcaagcata agggctatcg ccttattcaa ggagatatat tgctgccaga
     6181 gctcatcagc caagagctca acatgccttt atcttatcat gagaaaagcc agtcaacaca
     6241 gctagacgcc aagcaaggaa tcgagctaaa gcatactgct cctaggctct atctcgctcc
     6301 aagtcagtat gcggccaagg ggcggcttaa tcgccaattc tttgcgtcac ctcatggcgg
     6361 catttacatg tccttgcatc tcaagccaaa tgttccttac gcagacatgc ctccttacac
     6421 catgatggtg gcctctagta ttgttaaggc tatttcaaga ttgaccggta ttgacaccca
     6481 aatcaaatgg gtcaatgata tttaccttgg ccataaaaaa atcgccggta tcctgactga
     6541 ggccattacc tctgtggaaa caggcgtcat tactgatgtg attattggcg tagggcttaa
     6601 cttttttgta accgaatttt ctgaaaacct caaagaacga gcaggctctc tttttagcaa
     6661 caagcctagt attactcgaa atgccctaat cattgacatt tggaagctct ttaccacaat
     6721 accaatcaag gaccatatta aggtctacaa agaaaaatca cttgtccttc aaaaacaagt
     6781 gagcttccaa gaaaatgatc gtcaaaaaac agcaactgcc attgacctga ctgatgaagg
     6841 acacctcatc gttcaattag acaatggtca gctacaggtc ttaaggagcg gcgaaattag
     6901 tctttcttcc tggggggatt aacagcatta atgatgtttt tggtaaattg gtcaatagca
     6961 taagcacgcc ttaaatctct aaagagcaaa agaccccaaa acagagcaaa aatataatcg
     7021 cctgaaaata ataaatcgct gaaaaaataa gcttcaaagg cacaaatgaa tgccataaac
     7081 ataaattgtc gaatagtcat actactatta taccaagaaa actaaatttc cactaacgat
     7141 tttcacgcag cttgaagaaa aaggcagtta gcctgcttca agcttttttg ctgctctttg
     7201 atagcctgta acagtcaaat aaaaaagagc tcactctaaa aacgacgcca aaagccagct
     7261 tgattgctag gcttgtagtc aattgtctca aatcagtgaa tcactaagcc ttataagaac
     7321 tcagtcattg ggtcacaatg acacctagct ctaagcagca aaaaagagaa ccacaccggt
     7381 cctctctagc ttggcttgtc agctatctat tagtgctgac aatgagccct gtcatctcct
     7441 tattctagac aattgataca ctaccaatca tcagctagcg ctaatcctct atgagatgaa
     7501 tcttatcagt taaaaagtca aacccctcag gcatgtcaaa ggtcgcttgc tcagactctt
     7561 tggctgtctc ttttttggtt ttgatggtca tggcaaactc cgagcgaata tggtggaagt
     7621 ctgcctttgg tactgccaag atatgaggag aaaaccctgc tgccttactc atgatattcc
     7681 caaacatatc attcaaatcc tgacgcttca tggcctgctc agcgttaaag gcggcctcaa
     7741 aggccaaaat agcattttca ctattggcta aaacaggctc cgagcctagt aacaaagctc
     7801 gatcctgtgc agaaatacta tctaaaatct cattccaagc actttttagc gcttctaaat
     7861 attgtcgtga ctgctggcta tcttgaacag tttcctccat gattttcaat atcttttccc
     7921 gatcaacctt gtaggtaaag gcctttggct tgatggaatg agctggtgta gcctgcgcag
     7981 ttagaccctt ttgagcctgt agctgtgata tcgtctccct cagctgacta atctcatgct
     8041 tcaagtcatc aacatcagct agcaggctag acggtatcgc agtgtctgct gcttgtcctt
     8101 gctctgccag ctgaatggtc atcatttcag cgtagattct aggatgggtt ccttttttga
     8161 tctcaggcaa atgcttggtt actgtagcaa tcattgtaaa aagctgatca aaagacactg
     8221 caaggttatc atcaaaaaga gctgactgcc tgtgatgatc accacctgat ttcacaatga
     8281 gcaggtctct aaaataggtt agcagatccg ttgcaaagcg actcatgctc ttgccactat
     8341 cataaattgt ttctagatta gctaaggcct gacttgtttt ttgcctgatg agatgctgaa
     8401 cgtagtcgtc taaggccgaa atagaaatag agcctgtgat ttcttctgca atagcaagcg
     8461 tcactcgatt gtcaaaggat aggctcaagg cctgatctaa aatggatagg gcatcacgca
     8521 tgccaccttc tgctcgtctt gcaattaaat gaagcgcctc tatttcatag gctatgccct
     8581 ccttgtccag tatcgccgcc aaatgctcac aaatagctgg ctgcttaatg gctttaaatt
     8641 caaatcgctg gactctagac aaaatagtag ctggaatctt gtgtagttct gttgtggcta
     8701 ggataaaaac cacattgtca ctcggctctt caagggtctt taggagcgca ttgaaggccc
     8761 ctgttgatag catatgcacc tcatcaataa tataaacctt gtaggttgcc cggctaggag
     8821 cataggttga cttatctcga atatcgcgaa tttcatcaac accattatta gaggcagcat
     8881 caatttcaat cacgtcctcc aggctgccag ttgtaatatc tcggcaaata tcacaatgat
     8941 tgcagggctc tcccttgacc tgattagggc agttcattgc cttagcaaaa attttggctg
     9001 cgctggtttt accagttcct cttggacctg aaaagaggta agcatggctt atcttttctg
     9061 actcaacagc ctgctttaag gtggtcgaaa taactgactg cccaaccatt tcagcaaagg
     9121 tctggctacg atacttccgg taaagggctt gatacattaa ttctcaactc caaacatgtc
     9181 aaaacgaaaa gatgtatttt ctagtaataa ggctacaaat tgctctaaat agtcttgatc
     9241 tatctgatca taatcagcaa caagactgga atccaaatcc agaacaccaa caagcctgcc
     9301 agccttaagc attggcacaa caatctcgct catggctgct gaatcacagg aaatgtaatt
     9361 agcatgcttt ttgacatcat caacgatgat ggtttgacca gattgagctg attctccaca
     9421 tactcccttg ccaagcttga tatgcacaca ggaaaccttt ccctgaaagg gaccaaggat
     9481 caattcttga ccatcaaaaa ggtaaaagcc tgcaaaaaca gaatgaggca gggtcatttt
     9541 taagagggca ctagcattag agagattggc caaggcattg ctttcattag aaaataaggc
     9601 tttagcttga gccaataata gctgataatg ttcaattttt gtcgtcttat tcatggttct
     9661 tattataaca tatctgctac taatcgttaa acgatttcca caggaaaaga attttaatca
     9721 gcctctctag aaaagaaaga gattttatga taaaatagtg agtaatatta aaaaaatagg
     9781 agagtcagat gccgttgttg agatataaaa agattatcgc tacgacctta tttatgttat
     9841 tagtgtttaa tggtattgag tatgaatgtc taaaccttgt cagtcccaaa caaacctttt
     9901 accaatccgc tgccttaatc ctctcaacca gcctactagg gatctatctg attccctttt
     9961 cactggctat tgcttatctc aagcgcatct accagataag gatctcaacc ctgctattag
    10021 ctgggctagg cggtctttat attagtggct ttttagcctc ctttggcaat caggttttag
    10081 agcaattttg gattagcctg ataaagccca atattgcctt agaggagtgg acgggagctt
    10141 tgacagggcc ttttgtggaa gagcctatta aggcctttgc agctatgctt gtcatttatt
    10201 tgctgccagc tattaatctt aagcaaaaat tagtcatcag tctcatttct ggcatgggat
    10261 tccagctgac tgaggacatt agctatattg caagtgcggc tgatcggtcc ataaatgaca
    10321 ttttgcctac aacgcttgcc aggattagca gctcaccaaa ctctcattgg gtctatactg
    10381 gtatttttac aatgggagca taccttttaa ttaaaaaatc tcaattattc ccaaggtctc
    10441 tgcagatttt ctgggtggta agtcctctag ccctacattt tatatggaac tctcctatct
    10501 cagatttagc tggtgtcgca gttattcatg gaacaataac aacccttatc tttatcagtc
    10561 tattcaaaaa aatccatgcc ctagacgaca gcatcgccta ctagcgtcat aggacacgag
    10621 caaccaagcc cagccgcatt tgggcatgtg atggctcata tgcatatata gctactcacc
    10681 tctcgcttaa gctataggca gctaaatacc tatcacaata gcagaaaaaa tgactaccag
    10741 tcttaaaagg gctagtagtc attttaagct aaaaacaagc acttcttaca ggatatacca
    10801 ctgatacaga taatagcaaa gcacaagggt catcagtatc cccatatacc atgaaaggac
    10861 aaaataccat ttcttcgttt tatggttaaa ataatgccca gctagatagg ctccaatccc
    10921 accacataag agtgacaacg ttaatagcat tttctcagaa agtcgccatt gacctttttg
    10981 ggctctgtgt ttatcactgc cataggccgc aaagaccaca gcattccaac caaaaagcaa
    11041 gattaggctt ggtagcattt gtctgtctcc aatcacagca ctacagctca cctaagatgc
    11101 tggcaatctt tgtgttgatg agatcaatag caaccacatt gctaacccct tctggaatga
    11161 caatatcagc atagcgctta cttggctcaa taaattgatg atacatcggc ttgacaacgc
    11221 ttgtgtactg ctcaataatg ctctcaaggc ttctgccacg ctcaaccata tcacgctgaa
    11281 tacgacggat aatccgaatg tcatcatctg tatcaacaaa aagcttgata tccatcagct
    11341 cacgcaaacg ctcgtcctct aataccagaa tcccctcaac aataatgacg tcctgaggct
    11401 cttggcgaaa agttctgttg ctgcgagtat gctccttata atcatagatt ggaatatcaa
    11461 caggccggcc agccaagagt tcctttagct gctgaatcat gaaatccgta tcaaaggcta
    11521 acgggtgatc ataattagtc ttaacccttt cctcaaagct gatatgtgat tgatccttgt
    11581 aatacgaatc atgctgaatc atcgcaattc tcgcatttgg aaagctattt aaaatggcac
    11641 gagacacgct agtcttacca ccaccagaac caccagtcac accaataata atgggttttt
    11701 taagcattgt aaactccaaa tctaaaagtc tttcggtcta ttttaccaaa tttgccacta
    11761 taatgctata atgaagagaa aacaaaataa aaggatagat atatgataac caaccttccc
    11821 actcaatggc aggaaaagct ggcaaagctt ggctttacta atctcacccc aatccaagag
    11881 caggtctttc agcccattgt tgatggcaaa agcctattag gcattagccc caccggaaca
    11941 ggcaaaactc tggcctattt atggccaagc cttctcaggc taagccctaa aaaagcccag
    12001 cagttgctga ttttagcacc taatactgag ctagctggac agctttttga ggttaccaag
    12061 gaatgggcag agcccttagg attaactgcg cagctcttta tttccggaag cagccaaaaa
    12121 cgccagatcg aacgcctcaa aaaaggccca gaaatcatta tcggaacacc gggacgcatt
    12181 tttgaattag taaggcttaa aaaaatcaaa atgatggcca tcaataccat cattttagat
    12241 gaatacgacg acctactgag tgactcccaa taccagtttg tccaaaaact ctcccattac
    12301 gcgcctcgtg accatcaaat gatctacatg agtgctacta acaagataga gcaagccagt
    12361 ctagcggatc ataccttggt cattgatctg tctaagcaag cattgccttg cattgagcac
    12421 tgctacatgc tggttgacaa aaggcatcgg accgatatcc tacgtaagct agcaaatatt
    12481 cctgactttc gtggtctggt cttttttaac agcctgtcag acctaggtgc tactgaagaa
    12541 cgcctgcaat atagtggagc ttctgttgct tctctagcca gtgatgtgaa tgtcaagcag
    12601 cgaaaggcca ttttagaagc ctttaaagag cagagcattt cactgctgct tgcgacggac
    12661 atagtcgctc gtgggattga tattgaccag ctagaatacg tcattaacgc tgaggttccc
    12721 cgtaataaag agcaatatac tcatagagct gggcgaaccg gtcgtatggg acgatcaggg
    12781 attgtcataa ctcttgtcag tcaccctgaa gacatcaagc gccttaaaaa atttaccaag
    12841 gtcactgaga tgtacttgaa gcatcagcaa ttataccaaa aagaaataag aggctagctc
    12901 aaaggatata aacctaaaaa gcttgcctcc aagtatgatg taaagcaact aatcactatt
    12961 tcttaccctt gctactaaaa aaacgaacgt aaagtccttc tgacatgaag tcaaaacctt
    13021 acgttcgttt tatattatac tgacaccact ggctttatta gtatagtaga tactggccat
    13081 gcttagccag actagatact ttcttgaagt gagcccgcca tttagtcatg ctctagagcc
    13141 ttacttgctt tttctgactg actagcggct accatatagc tcagataagg tcacacattt
    13201 gtatccttcc gcttttaggt attccataat acttggcaag gcatctacac tggtctggtg
    13261 aatatcgtgc attagaacaa cccctccagg ctgcaattgc tgcttgacat ttgccatgat
    13321 agcagcagta ttacgatttt cccaatctct ggtatcaact gtccaaagca tttccttaag
    13381 acccgatgcc cttctaacaa tatcattagt agctccataa ggaggacgaa gatagactgg
    13441 gcgttttcca caggcctttt cgatggcttg attggtcgta ttgatctgtg tttggatctg
    13501 atcaacggtt agggtcgtca aatcagggtg atcccaagaa tgattctcaa catcatgacc
    13561 agcagcacta accttcttaa ccaaagcctc atggccaaca accttagacc ccatcataaa
    13621 aaaggtcccc ttggcctgat atttggccaa aatatctaaa acctgcggtg tggtcacagg
    13681 gtctggacca tcatcaaagg tcagagcgac tagcttttgt ccctcttttt ctgcctcttt
    13741 tgccttcttt tcctccaaat actcttcata agcagtcttg tctgaaccct ctagaaaatc
    13801 tggattaatc acatcaaaca ggcttgcaag aggtattgac atatgaccaa ataaaataag
    13861 attacccgaa tcaatggcaa agccatcgct taatacctga tttttttcta tcatcgtatc
    13921 agtgctcagc ttgatctctt tgcctggata aagcttgcca acctcttcct cgatgcgatc
    13981 taagcgacca gcaactagct cctctagctt aaaggggcta taatcctctt tcacatggta
    14041 acgactaaca gccttttctg tagtcttttt tagaccaaat aactgaggct tgtagaccgt
    14101 cttgtagata accaattgat tgacctgctt gatatgtgaa gcctcaagct taggctttac
    14161 catgataaca gccttgtcag tctgcttgcc ttgatacaga gacataggca gatttgacac
    14221 ataaaaatcg tcagccttct caatcggaga caggtaatac caatcctgct ttcctttctt
    14281 gagatacttg acctttttga tctttggact atccttagaa gcagtctgtt cgagcttaat
    14341 gactctctga gtatcctgcc ctattttcca agatctaatg aaggtaaacg caacaccgac
    14401 caacaataaa cttaataaaa taatgagaat ataatttagc tttttcaatc tcgtcctcca
    14461 attaccctac aattttaaca caagatagtt ggaaaataaa taaaaaaagt taggtttcct
    14521 taactttttt cagtccaaaa taagggcaaa aaagtgtttt atggtgcagg atttgcctga
    14581 gttattttcc ctttatcaca gccatttgtc actggataag gggctagata ttatacctaa
    14641 agcttctctt tattgctatc attattctga cattcttagg catgctattt cccttgatag
    14701 gacttgattg ctgtttcttt agcttgtaag gatctcctaa aaatgagagt atttttaagc
    14761 ctataattta tatattcgaa aaattttgac aaaaatgagg aaaaatattg atttatttag
    14821 ctttagtgat aaaatgaggg tgaaaaatta aataaaggag gacattgata tgtctcagaa
    14881 gttgggaaaa caacttattc gctctgttgt tactgcctta gccgccatag catttggaat
    14941 atttcctgca agcgagacga ctaatcatat cacctatgca gaggttaact ccttaacccc
    15001 ttcggtagaa tggcctttag agcagtatcc taattactat agcatagaag gaaagtctaa
    15061 tatcaacacc aaggattttc ctaagctata caccactacc gaaaaggttt acaaaaaaag
    15121 tggtcgaagc actaagcgcg ttactgtttc tgatctgcaa tacgctgcac ttgatggcta
    15181 tggccgttca ggagctgcct atggtattat cacaaaggat atgatcgcga tgtcagccgg
    15241 ataccgcgaa aaatgggaaa gcaatcctga gccaagcggc tggtatacat atcatttcaa
    15301 agaaactggc aagctagcta ctgaggccga ctaccttcac agcaaaagca agatcaaacg
    15361 aacctcaaac aatagctatg aaagcatcgt ccttagcaac ggtaagattc gcaacggcta
    15421 tctttttgat cgtagtcatt taattgctga cagcttaggt ggtcgtcctt ttagaaataa
    15481 tctcatcaca ggtacacgta ctcaaaacgt tggcaacaac gaccgcaagg ggggtatgca
    15541 gtacattgaa aacaaagtcc taaactatat taaccacaac cctcaggttc acgtttatta
    15601 caaagccgta ccaatctact caggctctga attactccct agggccgttg tggtttcagc
    15661 gctctcctct gatggtaaaa ttgatgaaac cgtaagagtc tttaacactg tcaatggctt
    15721 taccatcaat taccaatata gcggcatcag ccatgataag ggcatggagg cttctagtga
    15781 gtcagaagct gaggatatta cagacgaaag cactccagta gctgaaccag ctgatgagga
    15841 ggctatggag acagaggctg ctgctaacga cacaatagtc tatgttacaa gtaatggcca
    15901 atcaaaggta tactggtata ataaggacca tctgccagag aaggtcaatc tcaataaggt
    15961 tgtagaaatg accgagcagg aagccctaaa tcgaggaaag caccattcct ccttagaaaa
    16021 aataaatcaa tagtctcata acgactaaca caagagctgg ttgaagcaac cagctttttt
    16081 tgtgtgatga aggattagac agctccttag ctaaaagata aagaggctga taaagcactc
    16141 aacctcttat cgcttttata aatgctctgg tactgcggct aatagctctg atagcttgct
    16201 tgcatcacta ccacctgcca tcgccatatc tggcttaccg ccaccacgac ccgacacgat
    16261 tggcgctaag gccttaatca gattgccagc gtgagctctt ttatccttac ttgcaacaag
    16321 aacattgacc ttctcaccaa tgcttgcagc cagcacaagg acatctgaat aatctctttg
    16381 cttccaatta tcagcaaagg tacgcaagac tcctgcatct gatacggata cctcactagc
    16441 aatgtaacgt agaccgtttg cttcctggac ctttttaaag acatcaccag cctgagctgc
    16501 tgctgctttt tcttttagct ctgccatttc tttttgcaaa tcgcggagct gctcgctgag
    16561 gctcacaacc ttacttggaa gctgttctat ttgcggcacc ttaagcgtat gtgcaatttc
    16621 ttttaggatg tcttcttgct tgcggaagct ttcaaaggcc tgctgacctg tcactgctat
    16681 gatacgacgt gttcctgagc cgatcccctc ttccttgata atcttgaaaa gaccaatttc
    16741 tgatgagttg gacaagtgag tccctccaca aagctcaaca gaataatcgc caatctgaac
    16801 aacacgaaca gttttgccat atttttcacc aaagagggcc atagctccca tagcctttgc
    16861 tgtttcaata tcagtttctg tggttgtaat agctaatgcc ttccagattt gctcattgac
    16921 ctcttcttca atacgacgca gctcctgggc tgtaacggct tcaaagtgtg taaagtcaaa
    16981 gcgtaaaaag gcttcttcat ttaaggaacc tgcctgagtg gcatgttctc caataacctt
    17041 gtgaagggca gcatgaagca gatgagtagc ggtatggttt ttctcaacag catagcggcg
    17101 cttgtgatca atagcaagag tataaacagt gtctaatgca aggcttgcaa gaacctcaac
    17161 agtgtgaaga ggctgaccat tcggtgcttt ttgcacatct atcacacgag caacaaggtc
    17221 acccttatca tttttgataa ccccatgatc ggcaacctga ccacccattt cagcataaaa
    17281 cggtgtctga tcaaacacaa gcaaggcctg tccttctgaa accatctcac tacgctcatt
    17341 atcaacgatg ataactgata agcgagaggc aacagtctct gtttcgtaca aaaattctga
    17401 tggctctgtg atgcctgcca gtgtctcatt ttgcatgccc attgagccac ccttaacagc
    17461 tgctgcacgg gcacgatcct gctgctcctt catagctgcc ttgaagcctt catgatcaat
    17521 cttatagcca gcatcttctg ctaattcttc ggtcaattca actggaaagc cataggtatc
    17581 atacagctta aagatatcct tgccatcaag cctgtcttgc cccttttcct ttagctgcgc
    17641 cagcaattga tccaaatgcc ctgatcctgc atcaatggta cgtgcaaagg tttcctcctc
    17701 acgcttgata attttttcaa taaagtcacg cttctcaaga atctctggat aataggactc
    17761 catgatatga cctacagtag ctactagctt ataaaggaag gtctcatgaa taccgagcct
    17821 acgaccatgc ataacagcac gacgaagcaa gcgacgaagc acatagccac gaccttcatt
    17881 accaggtagg gcaccatctc caatcgcaaa tgacaaggca cgaatgtggt ctgcaatgac
    17941 cttaaagctc atgttgtcac catcttggtc gtaagtatgg ccagatagct tttccacttc
    18001 cttgatgatc ggcataaata ggtcggtttc aaagtttgtt tttgcgccct gcataacagc
    18061 cacaagacgc tctaagccag cacccgtatc aatgtttttg tttggaagct ccttgtactc
    18121 tgagcgagga attgtagggt ctgcgttaaa ttgagacaaa acaatattcc aaatttcaat
    18181 ataacggtcg ttttcaatgt cctcttccag caatctaatc ccaatatgat caggatcata
    18241 agcctcacca cgatcaaaga aaatctctgt atcaggtcct gacgggcctg caccaatctc
    18301 ccaaaaattt tcctctaatg gaatcaaatg gcttggctca acgcccagag caatccaacg
    18361 attgtaagag tccttgtcat ctgggtagta ggtcatgtat aatttttcct ttggaaaatc
    18421 gaaccattcc ggacttgtta acaattcaaa gccccactca atcgcttcgt cgcgaaaata
    18481 atctccgata gaaaaattac caagcatttc aaacatagta tggtgacgag ctgtcttacc
    18541 aacattttca atatcgttag tgcggattga cttttgagcg ttggtaatac gaggattttc
    18601 aggaatgact gacccatcaa aatatttttt gagggtggcc acaccagagt taatccaaag
    18661 cagggttggg tcattgactg gcacaagatt ggccgaaggc tcaatagagt gaccttttga
    18721 tttccaaaaa tcaagccaca tttggcggat ttgggctgat gttaactgtt tcatgattaa
    18781 gataccaaga gcgattagag agactgggta tgattgtcct tagcataagt agcctgggga
    18841 gacgatctct actcgcattc agttcctttc gttgattttt tatgggatta ggctaaaagc
    18901 catcaaaaca aaacaagccc atatcacaga gggcgaaaac cgcggtacca cctctattca
    18961 atgagcttgt cattcttaat tacttatatc agataaaatc acattaagca gcatgcctat
    19021 cagattatcc gtaactcaca gcaaccgtca cttctctggg tcaaatcctt gataaacaat
    19081 tcttaactaa accagtataa agcttttttg agcattcgtc aatgaaaatc tatttttctg
    19141 acttagattt agaagattga ctatccttgc ttgagtctga agatgatttc tgatctgact
    19201 tgcttgtgtt cgccttgctt gcttttttat cagtattggc atactgtgcc aagatattag
    19261 caaatgcttg gtctttgatc ttaacatttg ccttgtctaa ggcctttgca atgaccttat
    19321 tttggaaatc aatgttttgt gtcttttcag ccaagacaat ttcttttaga cgtttcttat
    19381 atttcttcca atcagaagcc ttttcggctt ttttggttac cttaacaata tagaacttgt
    19441 tttgataagt agccggatct aagacagaaa ccacctctga aatatcaccc tcttttaatc
    19501 ctgaggcggc cttgatcaca tctgctggta acttagtgtc tcctgagtca aacttatagt
    19561 ctaccttctt gtctgctgct gttgtctttt ccttagcaat agcagcaaag tcagcaccct
    19621 cagccttaac ctcacctaaa acagcctttg ctgtttcttc attgtctaga gtagtgacct
    19681 gagtagtcat ttctggtgtg tatgactcat aggctttttt gtaatcagca tctgtcagct
    19741 cttttttagc tgcttcttta acagcatatt caaccagcat ggctgagcga atttgacgct
    19801 tgtaggtatc tgttgtcaag ccagactgcg caagggctgc agagaatgac gcaccgtatt
    19861 gctcagctga tttattgtaa gcttcttccg ttcttttctt agaaaccttt ttaccgtatt
    19921 ggtcctcaaa aacacgacta accacaaggt ttagcattgc tctttgagaa atctctgtat
    19981 tttttgtttc attgtaaaaa tcactaacac tgatagtgtc gcccttcatc gtaatgacac
    20041 ttgtattgtc atttgtagac tgacaggctg ctagggtcat tgctgatgct agggttacga
    20101 taccagcaag taatttagtt gattttttca tgtgattttg tgctcctttt tgtcattaac
    20161 cagtatatta tatcacaatt tcttaaacgt aacttaatct aacaaacgaa tatctgcttg
    20221 atttttacga atcatcagca agccatcact aagcggcagc aggctggctg tcaatccagg
    20281 attatcaaga gttgctgcaa ataagtcctg aaggccacga taaatcgtgc gctgtcctct
    20341 ccgaacctcc ttgatcggct tagcaatgtc acccccctga aacacatcat ctaaaacaac
    20401 cattccacct atttttaagt gctttaacac ctctggaaga aactgaatgt attttgattt
    20461 tgcagagtcc ataaaaacaa agtcaaactc gccagtaagt cctgctaaaa gatcagccgc
    20521 atctccttca agaagggtaa tttgcttgcg gctatcgtat tttgcaaaat tttccttggc
    20581 aaagccaatc atctcagcat tgcgatcaat cgttataatc tctgcctcag gagcattttc
    20641 tgccattagc aaggcagaaa agccaatagc tgtgccaatt tctaaaatcc ttttgggctg
    20701 caagctttgc aataaaagcc tgaaataagc aacaacctca tgctggataa tgggaatatt
    20761 ttcttgtctg gcaaaggcct caagctctgc taaaaagcct tcgttttgct ttagctgcgt
    20821 tcgcatgtag tgaacaatgt cttctttgac aatagagcgg cgcatattat gatttgcatt
    20881 tttactatat gatttaacca tgctatccat tatataaaaa aactctaggt aatgctaggg
    20941 ctttcactag cctattcacc tttgacgatc tgagtagtat ctatcaaagg agctcacaga
    21001 cagccttaag ctgcttgaca atgctatcac aagcagacaa gtcctgtaag ggataatcag
    21061 gattggcaaa gccgatacag gtcatctgag cagccttagc agcctgacta ccatgcttac
    21121 tatcctcaat gacaaggcag gtcttgggat caacgcttaa ccattcagca gccttaagaa
    21181 aaatatctgg cgctggcttt gagcgagcaa cctcttcacc actaactaac acctcaaagc
    21241 agtccaaaag acctagtgca gtgagatttc taataatatc tgccttaggc gatgaggaag
    21301 ctactgccaa gcgatagccc ttcgcatgca ggtgcttgat taattgagca gcacctgcta
    21361 tggccttgac accgtcacgc tcaagcattg cttgacgacg atgattcatc tcagcgatga
    21421 gggcttcaac agaatcctct agctgacact cctttttcat agttgtccac atatcgtcaa
    21481 aggtggttcc cataaactgg tactgatacg cttcattggt atctatgcct cggtccaata
    21541 gcatttgtgt cttggttgac aaaaagatat attctgagtc aacaatcaca ccgtccatat
    21601 caaaaataag gcttgttttc atcatctacc tcctcttatg ctatatctca gtcaggtcaa
    21661 gagcaagact attaattact agagctattt ttaccagaaa aaagctcaac aatatctgac
    21721 agctgactaa tatgatgatt atcatcacta tctggcagca ataggttgat agagctaatc
    21781 ccagctgccc ttgctgcagc aaggtctaag ggcctatcac caatatagta ggtctgcgac
    21841 ttatccatct gataatgatg aatgagaaaa agaagcgctt cagggtccgg cttacgctta
    21901 aagccacaat ctgctgtaat cacctctgta aagtaatcag caatccccag acgctgcaaa
    21961 acagcctgag tggttcgtcc tttatgagtc acaataaaag gcttaacccc ctgctgagag
    22021 gttaaggcta atgtttcctt ggctgtaggc attagtgcta ttaggtgatc acgcgcttcc
    22081 tgctctcggg taaagaaggc cagcaattct gaaaaatcca gctgatgtgc ctctgctaac
    22141 ctcttcaaaa gctgtccgat ggattcttga ataatcgtat ccataaccca agcctcatca
    22201 aagggcagct gataggtctg atacaataaa cctagcgcct gacgaatagc ctcagaggat
    22261 tggactagag ttccatcaaa gtcccaaatg agattaactg tcacaatcct tacctcttaa
    22321 atcaatccaa taacgagcaa tagcctgccc tgctaagctt gtagtagggt aatcatctgc
    22381 cacctgaaca atatcctcta aaataccacc agccttttca atggtttttc gactggctat
    22441 attatcttta ttagctgtta ttaagacacg cttgatccca cgctcttgat attgctgtaa
    22501 tgcaaaggcc agcaagtctg tcataattcc acgcccgcga taatctgtcc ttgtcacata
    22561 gccaatatgt ccgccaattg ttgctaagtc tcctttttcc aactgccagc gacagcctat
    22621 tctagccact agctgaccat ctaaaaaata gtaataatta gtgctagtgg accagtcagg
    22681 atgatcagtt tggacctcaa accgtctaga ttgctcaaca aaggctgcaa agtcctctac
    22741 ttttttggtc tcaacaaagg tattacctga agctttttca gctaacagta tatcctgaaa
    22801 gcgcttaaag gctgcttgat cagctaaagc aattgttcta atctctttca tgcctggctc
    22861 ctttttatta tgctaaaaat caactgggca tttctcaagc attcatcatg ccaacgaaaa
    22921 agagctgccc ctagaactgt tgatgtaata ctacgtctag aggctgccca caggccttta
    22981 agctaggctg atagacactg actgctgcta tttaccaata gctcaaaacc taagaggaga
    23041 tggcaactat tagagatgtg cccctcttgc cactaagtcc tctagctctg tcaaacgctc
    23101 ttcaaagacc ctaaaggctg cttctaggta atcaccctta gccatatcaa caccagcctt
    23161 ggcaatcacc tcaagcggat aatctgaatt tccagacttc agataggtca agtagtgatc
    23221 aatatcctct tgagtaccat gcacgatctt atcagccaag tagctggctg cagcaaagcc
    23281 tgttgcatat tgatagacat agtagttgta atagaaatgc ggaatgcgag cccactcata
    23341 ctggataaaa tggttgtcct ctttttttaa gccataatat ttttcgttta aatcagcata
    23401 gagattattg aggtattcac ttgttaacac ctcgccattt tgatccgcct gatgaatagc
    23461 gtgctcaaac tcagcaaact gtgtttgacg aaaaaccgtt ccacgaaaac catctaggta
    23521 atgattcaaa atagcaaagc gctccttatc atcctgcacc tcatgtaaca aggcctcagt
    23581 catgatattt tcattagtgg ttgaagcaat ctcagctaag aaaatgctgt aatctccata
    23641 cacgtaaggc tgtgtttcac gcgtaaaggt tgagtgcagg ctatggcctg tctcatgcac
    23701 tagcgtatag aggttatcaa gcgtgtcctg ccaatttaag agcataaagg cattggtatc
    23761 ataggaacca ccagagtaag ctcctgagcg tttgccctta ttgacatgca catcaatcca
    23821 acgctctgta aaggcacgat gcacacgctc tgaataatcc tggccaaaaa cagccaaaac
    23881 cttctctgct ttttccaagg cctcatcata gccgatagca agatctgtct cagataaagg
    23941 agtataaaca tcatacatct ttagatcatc taaaccaagc acctcttgac gtagcttcaa
    24001 ataacgatga agcagcggca aatgcttatt aacgttttct agtagggtat cgtaaacagc
    24061 ctctgggata aagttggctg acatcgctgc ctgacgggct gaagcatatt tgtgaacacg
    24121 tgccttataa ttttgcacct ttacattggt ttgcagggtt ttagcatagg tgtgctggaa
    24181 ttgctcataa gtactataca tggcttcata ggcagcccta cgcaccttgc ggtctttcga
    24241 ttccatcaag ctaatgaaat taccatgtgt tagctcaacc tcttctccct tatcatttgt
    24301 cacaatagga aaagcaatgt cggcattatc taggatacta aaggtctcct cagcaccatt
    24361 aaagatttct tgtgcccctg ctaatagctc ctcctcagcc tgactaagga catgctcacg
    24421 cgtcttgaac aatttatcaa agaaatggtc atagactgtt agctccggtg tctcagctaa
    24481 gaaggcttgg taggcttcct gacttaaggc cataaattct ggctcataga atgaaaaggc
    24541 ttcactaaat ttagcataaa taccagaggc cttagcttga tattcttgat acttggcaac
    24601 tgtcgtatcc tgatcatttt tcatgctagc ataaacataa accttttcaa cacgacgagc
    24661 cagctccaaa tgcagctctg tgatatctaa gagactgctg cttgaatcca acaaatgccc
    24721 agcctgctgc cttgcagcct caattgctgc cagcagacta tctgcctctg tctcccaagc
    24781 tgcgtctgtt gcaaaaatag tgcttaaatc ccaagtgtac ttttcctcta gatgactacg
    24841 attatctgtc atacggacct cctaagtttc tattactaat cattttaaca taatatgctg
    24901 gtgaaaaaag cttttgcacc tctttatttg ctgcttttgc gtaatatttt tcaaagcaat
    24961 cgtaatagtg gctcaaatcc tcatgaatct ggcaaaagcc agctgagcaa gcaatcggct
    25021 taacctgtgg ataataagcc tctaggggcc tatcaagcag gttatcccca gctagataag
    25081 cctcttcttg ctttttcaac catttgctat cttttgctag taaggctttt tgaatccttc
    25141 tcagcaagtg cttatccatc tggagctgat aggctgacag gccttttctt tggtaaggca
    25201 gccgcaaaaa ggccaacaaa tcatcatcta aggaacaggt ctttactaga tagctgacct
    25261 taccaaataa atcctcatga atcata
//
LOCUS       DARYLJ010000035        24188 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYLJ010000035 DARYLJ010000000
VERSION     DARYLJ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24188
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(93..869)
                     /locus_tag="TU746_001340"
                     /pseudo
     CDS             complement(93..869)
                     /locus_tag="TU746_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            complement(965..2512)
                     /locus_tag="TU746_001341"
     CDS             complement(965..2512)
                     /locus_tag="TU746_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL0891685.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            complement(2487..2726)
                     /locus_tag="TU746_001342"
     CDS             complement(2487..2726)
                     /locus_tag="TU746_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0891686.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            complement(2739..4862)
                     /locus_tag="TU746_001343"
     CDS             complement(2739..4862)
                     /locus_tag="TU746_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0891687.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            complement(4866..7295)
                     /locus_tag="TU746_001344"
     CDS             complement(4866..7295)
                     /locus_tag="TU746_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0891688.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(7207..7596)
                     /locus_tag="TU746_001345"
     CDS             complement(7207..7596)
                     /locus_tag="TU746_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL0891689.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            complement(7600..7863)
                     /locus_tag="TU746_001346"
     CDS             complement(7600..7863)
                     /locus_tag="TU746_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0891690.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            complement(7883..8749)
                     /locus_tag="TU746_001347"
                     /pseudo
     CDS             complement(7883..8749)
                     /locus_tag="TU746_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8769..8984)
                     /locus_tag="TU746_001348"
     CDS             complement(8769..8984)
                     /locus_tag="TU746_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL0891691.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            complement(8988..9299)
                     /locus_tag="TU746_001349"
     CDS             complement(8988..9299)
                     /locus_tag="TU746_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0891692.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(9463..11244)
                     /locus_tag="TU746_001350"
                     /pseudo
     CDS             complement(9463..11244)
                     /locus_tag="TU746_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565754.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(11241..11726)
                     /locus_tag="TU746_001351"
     CDS             complement(11241..11726)
                     /locus_tag="TU746_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL0891693.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            complement(11723..12497)
                     /locus_tag="TU746_001352"
                     /pseudo
     CDS             complement(11723..12497)
                     /locus_tag="TU746_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(12494..13273)
                     /locus_tag="TU746_001353"
     CDS             complement(12494..13273)
                     /locus_tag="TU746_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL0891694.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            complement(13360..13641)
                     /locus_tag="TU746_001354"
     CDS             complement(13360..13641)
                     /locus_tag="TU746_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891695.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TU746_001355"
     CDS             complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TU746_001355"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL0891696.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            complement(15370..16800)
                     /locus_tag="TU746_001356"
     CDS             complement(15370..16800)
                     /locus_tag="TU746_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL0891697.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(16999..17493)
                     /locus_tag="TU746_001357"
     CDS             complement(16999..17493)
                     /locus_tag="TU746_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL0891698.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TU746_001358"
     CDS             complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TU746_001358"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL0891699.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(18902..19840)
                     /locus_tag="TU746_001359"
     CDS             complement(18902..19840)
                     /locus_tag="TU746_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL0891700.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(19842..20702)
                     /locus_tag="TU746_001360"
     CDS             complement(19842..20702)
                     /locus_tag="TU746_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL0891701.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(20719..22002)
                     /locus_tag="TU746_001361"
     CDS             complement(20719..22002)
                     /locus_tag="TU746_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL0891702.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(21995..22549)
                     /locus_tag="TU746_001362"
     CDS             complement(21995..22549)
                     /locus_tag="TU746_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0891703.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(22843..24132)
                     /locus_tag="TU746_001363"
     CDS             complement(22843..24132)
                     /locus_tag="TU746_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL0891704.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         6488 a         5525 c         3925 g         8250 t
ORIGIN      
        1 gcattaaagc aaagctaaaa ggacttagcc ctgtgcaata cagaactaaa tcctttcaat
       61 aattattcgt ccaacttttt gggggcagta catttagtaa tcttttcttt ttgaatgaca
      121 tcagttattt caatcttatt gcccactaaa gttaagagct gctctgctgc tatttcatca
      181 tcaattctat ctgttgaaag tgtaaagcta tttgtagaaa gctctaccgt ataatatttt
      241 tctttcttaa agtttgctat ctcatcatct ctttttacga tcatagcaag agtcggtgtt
      301 tgtactctgc caacactgta attttgctta tacagacaag aatagagcct gctgatattc
      361 attccgacaa gccagtcagc gatagctctt gcctgtgccg actcaaagag attatcgtaa
      421 tcttttccgt cttttagatg atcaaagcca tctttaatgg cagtatcttc catagatgaa
      481 atccaaaggt gtttcatctt ctttttacaa ttcacttgat tatatacaag tctaaaaatg
      541 ctctcccctt ctctacctgc atcgcacgca ttgataaccg tatcaatttc tttgtcgttc
      601 atcaactttt taaggatgtt aaattgtttc ttggttgact ttgccacttc atacttatag
      661 tccttgggga taatcggtaa atcaaccata ttccacttgg catacttttc atcataaaca
      721 tccggatttg ccatttgaat taagtgtcca acacaccaag atactttgta tccatttccc
      781 tcataatatc cgtctttctt tttatttgct ccaagtactt ttgcaatact taatgctaca
      841 cttggttttt ctgcaatgac taacttcatt tctgtactgc ctcctgtttt caatataaaa
      901 gggcgaaaga ttttattctc ccgccctgca tttgcaccaa atactgtatt tttttggtgc
      961 agcattactg ctcatcttcc gcttctactt catctacatc atttgtttct tcctcgcttt
     1021 cagcttcaga aaagaaatca tcatcttctt cctctaatgc ttcaagctcc ttatcttctt
     1081 tcttttttac aaccttaaag tagtatcctg ctcccaatgc tccgcctaca acaagaagca
     1141 gaataatata tgttcctaaa ttactctttt cttctttttt ctcaggcttt acttcttcct
     1201 taacaggttc ttcttttaca atctcctgct ttggagcttc ttttttctct accatgttaa
     1261 gcaaatcatc ttcggatact tctgtaagaa gcatgacatt ctcactatcc tcatcgtggt
     1321 tgatgatgag atgaaaggtc ttaccgtttt tagtttgaaa ggtaataaac tgtcttgcat
     1381 cagcggaata ttgatccgtt tctttattat cgctgctatc cccatgatga atcggataat
     1441 ctttatttcc attatcttta ttttctgtaa cagttcctct tgcctttgac ggagatgaag
     1501 ctactccctt attggtattt acattactac ttgccccctc cattgacgaa tcttgactgc
     1561 tgttattagc aggtgctttt gctgtcaatt tattagaata gcgaacttcc ttttctttct
     1621 cctttacttc tgttttgctt gtatcctttg tagcattccc tgaactcacc gtatcagatg
     1681 agcctttacc ggaactactt acagaagtct gtggtgtttg gggagaaatg cttgagcttg
     1741 tcttaattcc ggaaatagga ctaatcggtg taacagaatt tattgcttca gaagatttct
     1801 ttgtttcagt tgcctttttc tcaagctctt tcaccttatc agtcagctta tctatttcct
     1861 ttttcatatc ttctgataag tccttatttc ctttatcttt cttcattttc tctttcaggc
     1921 tgtcaatttc atcttcaagg tctttgattt tttctttctg cttatccttg tctttaagct
     1981 caccatttaa cttatcaaat ttttcttgaa gctctttagc ctctttttcc atcttagaaa
     2041 tatcgtcttt agaaagctct gtctgtgtgc ctttatcctc cgtttttgta gcttctgttt
     2101 gcgtgctttc gtcctgcttt ggtttttctt cttccgtttg cgtttcctta tccttaacct
     2161 cagtctttgc taccttacgg ataatttcat catttccatc tccctttact tcataaaaca
     2221 ggaattcatc aataaatttc atatcatcag ggagcattgg aagatcgcca ctatcaagaa
     2281 gctgtccttt ctctgcctta atcttttctt ccttaaatac cttttcatct tcaaagatat
     2341 actttacatt tacttcaact tccgtttgga cagcttcgtt ttttgtagga gcgtcagagc
     2401 ttttctcctt ggcgtaaaca accgtccaaa gtcctaaaat gcagctaata cttacaatta
     2461 ctgcaagtgc tgctgtccaa aacttattat tctttttcaa actggttttc atttgtcctc
     2521 tcctttttca gttctgcttt ttctctgttt acctttgtca ttaaatcaga aattgtgatg
     2581 ttgttctttc tgcaaatcat gatgatttct tcattttcaa gttcttcttc acgaataaat
     2641 aaaggctcca attcttcatc aatcagagcc tttttatcct ttaacttttt tattctgttt
     2701 tttactgctg tcagttcttt tttcatattg ttccctcctt atctgtttac atttggtgga
     2761 aaaccaaagc ctaccggatg gtgtttacaa aaagtcgcaa tccaatcatc taaagtagtt
     2821 actcttatat aaccgatatt atcaataacc ttgccgtctc cgatatagat tccgacatga
     2881 ccataggtaa gtcctgctgt gcttccgcta ctgctgcttt ctaccgctac aagcattcct
     2941 accttgagct ttgacctatc ggatgtaaag gtatagtttc gatacatatc attagcattt
     3001 cctccgatat atccaagtcc cgcattttgg taaacttgcg atacccacat ggcacaccag
     3061 cctgcacccg gagatggagt gatatatgca gcattaacaa tcttcttttg tacttccgaa
     3121 gatgcctcat actctttccc accacctaca ccgccattag cactgataag gtcagaattt
     3181 ctaaaggctt ctcccatatt tccttgagca aggaataagg cttcatagtg ctttaaatta
     3241 tcgggatagt ctttaaagac ccttcggata atgctgtcca tctctttttt atgaagcgtt
     3301 acaatgagct tcttatattc ataaggctct tcatggcttt cggtatattc attgccatct
     3361 tcatcggtat aggtttctgt aactgtcctg tatctgattt caatttcttc cctgtattca
     3421 aggtcataca tggactcaaa caattctttt aatatggttt ctacttccga tacactcttt
     3481 acctctccgc accttgatgt aatgtaggat aaaagctcat ggacattatg accgatatac
     3541 tctgtgttgt ttaagatata ctcatcatat ccgggataat tctcttctac atgatccact
     3601 tcactttgaa gctcactctc catagcagaa aacttctgat tgatttcact tagaacattt
     3661 ggctttgata aatagcttgt tgtaagaaca gagtttgtag agttcataaa gcctgtcatg
     3721 cctgttcctg caaagttaat cacaaaattt cctaagatga tgatacctac gaagataagc
     3781 attagtcctt tggcttttcg gataatcata tcctttgagc ttttcagtgt tccgataagt
     3841 ccctctttaa tccgatctct gagtcttgac ttattctcac gagaaatcgc tgcctttacc
     3901 tgatttttct tttgaaatct tttataggca cttgctcttt tatactcatc tgtctttttc
     3961 agttcctctt tggcatcacg aaactctaac ttggatttac gctttctgat tttatagtcc
     4021 ttatttgtaa gctcatatcc ttttttagct cttttcttat ctgagtatct ctttatacca
     4081 tgaatgagtt ttgaacttgc atcggctgtt ttttctcccg cttctacgcc tttattttca
     4141 tcacttccat gagaaaggta atctcttacg gtttcacttc ctttggcaag tcctgacagg
     4201 gcagatactt ttaccatatc tttcttcagc tttttctttt ggtcttttga aagactgcta
     4261 tgttcttttt cgcccgcaac atctttccct gcctttttat cttcaggctt attctctttt
     4321 ggtacatcgt ccttttttct tgtatagagg ctttcggaat agtttttcct tttatactta
     4381 ttcttttgag ccttatgatt tttagaggga ttttctaatg atttttcttt ttgaggtaga
     4441 ttatcctcta catcataggt tgattcaaag tagtcgctgt ccctaaaatc attatcgtat
     4501 ctgtctatga ttccatcatt atcaaggtct tgtcctaaag aatcatagat tttcccgttc
     4561 tttacctcag tatcatagtc agcctttcct gcttcattta cacttccctt atcagaagcc
     4621 ctatactttg catttctttt agaagtcccc tctatctgct cattttcaga tcttaccttg
     4681 cttatcttct catgaacctt gtcctgaaat ctatctttgt catggacaat ttttcctctg
     4741 taatcatcgt tatgctttag cttactttct tcaggtatag agcttgtttc agctttaagc
     4801 atctcccttt caaggcttgc cttatgcctt tctctaaaat cttttttcag cttcccatcc
     4861 ataagctacc tcacttcttc aggcttggta gtcatcttct gataaagaat tgtatctttc
     4921 ggaaacttat caaggaaagg cacaatggta tttccaaaga aaagtagtcc ctcgccctca
     4981 ttggagttcg taacatatct aagctgcgga agtgagattt taagtttcct tgcaagtatt
     5041 tccctatctc ccgaagcctg atttaacatt aagacaaagt ccgtattatc aaagatattt
     5101 tcaatttcct tactcataag taggtctttg acattttgcg tgataccagt cgggattcct
     5161 ccccattttc taaaacgctt ccaaatctct accgaatatg aagctgtctg ctcatctttt
     5221 aacagcaagt gaaactcatc tatatagtac cttgtagcct tgtttcctct gttttgcgat
     5281 accttattcc acacctgatc ctgtataaca agcataccta ttttctttaa ttgacttcca
     5341 agctccttaa tatcaaaaca aagtagcttc ttatttaagt ccacatttga cctgtgatta
     5401 aagacattaa gagaacctga aacataaatt tccatctctg ttgccagctt tttccctacc
     5461 ttttcttcct gcccttttaa catatcgtat aggtcttgaa gtataggcat attgtcataa
     5521 gtcggatttt caaagtacct ttcgtaaatc ttaggtaagc atctatctat aacggacttt
     5581 tcttccgctg taagtccact accaccaact acaagctcaa gcatagacat aatgaagttt
     5641 gccttgtctt taagaggtgc gtccccatca ccgtagttca tatttatatc aagtggattc
     5701 aggtaatctt ttgacttact gctgacctta atgacttctc cattaaactg tcttacaagg
     5761 tttccatact ctccctccgg atcacagata atcacatcat cgtccgttac taaaatcgca
     5821 tttgccatct ctcttttggc actaaaggac ttaccactac ccggagttcc taagattaga
     5881 ccgtttgggt tctttaattt ctttcgatcc gccataatca ggttatggct taaagcgttt
     5941 agtccatagt ataggctatt acttgaattg ataaaaagct cctctgttgt aaaaggcata
     6001 aagactgctg ttgatgatga ggttagccct ctatctattt caatcttgtt taccccaaga
     6061 ggcagcacgc tcactaagcc ttgttcctgc gtatggtcaa gtcttttcaa tttacagtta
     6121 tgcttgtttg caatggagct tatctgagct atggtgttat cgagcttttg cactgtcctt
     6181 gcaaaattca taaagacaat acttacaaca aacatacgct catctcttgt ctgtaaatct
     6241 tttaaaagac tttttacatc ttctccgtaa gtaattaaat cacttggaag aatgtccatg
     6301 tcatagcctg accttacagc tttcttgttt tcctcaattc gcatcttatc aatatcggtg
     6361 ttttttcgtt ttaccatctt gatggcttct gactggtcaa tcgccttaat atgaaaagat
     6421 atattgatgt tatcatcaat atccaaaaac tccgataaca tacggtctga aagctcactt
     6481 gcaaggattt gaaaatgact tgttgctccg ataaacttcc caaacttgaa atacctgctt
     6541 ggcataaagt taaattcatc aggcacgata tatgttttgg tactttcctt tttcttcagg
     6601 tctttgtagg aaaactcaaa ggtcttattc ggatttaata tatcgtgaag aatctttagc
     6661 ctttcctcta ctgtaagact ttcagctctt acccccatgc ttttgagatt agataatata
     6721 tctatatcca atctttcaag ttttgatgta gcctgttcta aattgtctgc ctctactgta
     6781 aaggttacat actttgattt tttcagtccg ttatttcctt ttacaatctg actttttagc
     6841 atctctctaa actcaagtcg tatatcgtca aatccgtccc ctttatccgg tatctgaatt
     6901 gccgatttca tttcttcgtt tcgtccaagc tgattgatgt aggaaaactc aatcgctatg
     6961 cttggatcaa aggaatttag aaagtttgca aactgattaa aaatcaaatc cctatcttca
     7021 tctaaagcaa gctgatagtt aatgtcctga aaggctatgc ttttactgaa gtgcttttca
     7081 tcgagctggc atatcccgct ttttaagagt ctaagatagg gaatggtatc ttctaccgta
     7141 tagcgttttt gctcttttct aaagataaga tcaagtagtc cgctcttttc tttgttagac
     7201 tttcccttac tttgctttaa gtcctttctc tcctttttta atgccttttt gttttcttct
     7261 aactttagtt gctgaatttt tcttttcttg ttcaaggtaa acctcctttc tcactctctt
     7321 tgccggctga taaaacttat gaaggtagat atgcttaaaa tatttctcaa aggtcagtcc
     7381 gtccttttca aaaagtgtga taaaaaagat tggaagtgtg gacacgataa ggaatatgaa
     7441 agctatatcg tttggtacta cctttctcat aaataaatag acaggtattc caacaagtcc
     7501 tgcaatggta aatcctatga gctgtctttt tgtaaggtta aaggctacct ttgtcttgac
     7561 cttctttaag tccttgggta ttggtacata cgccatagct tacctcccat cttctttacc
     7621 ctttgaaaac tcctcaaagt gttcatatac agagccgatt tcatcctgaa taattgcaag
     7681 ctgttcatct gtattcttgt tatatctttg ctgcattaag caaaaatcat tatggcagcg
     7741 accgatgtcc tgtgttcttt cttctaattc ggcagctttg ttatgaagcc tgattctatc
     7801 aattaccgcc ataatgcctg cgaccattac tactgctgta aatactgttt ttcttttatt
     7861 catactatct ttcctttctt ttttagtgtg catttaatac gcttttggcc agtgttccgc
     7921 tctttagcat cattaacccc agcaaaaccg cataaccaag tatcgtcatg gtacttgtgt
     7981 gtatatctgt tatttcaatc gtcttaacta atactgcgta aattccaaga caaaccatta
     8041 aaaagagtcc ttgtagtcca agtgcaaata atcctttgat gtaatttgtg ccaatttgcc
     8101 cccattcttt gtttcccatc gtggcaaatg gaatggctga aaccgatgaa taaacataaa
     8161 tctcaaacat ccttccgtaa accacaagca taatcactat ggaaattgcc tgtatggcaa
     8221 ctttaatgag cgaggtttca aagagaatca tgataagctc tccaagtccc ttttctttta
     8281 gggtatccat catcgccact atctgatctc cggaaacggt ggcagaggtg tttatcaccc
     8341 ctgccgcctt atttaccata tgctgtgcta catcaaagac cgccattgaa aattcaaaag
     8401 cgtgagatac caaccataca gcaattcaca tcttgatgat gtacttgaaa aattcaaatg
     8461 tatccgtatt atcatgtagg ttatttttct gtataaccat attgataagc tcgatacaaa
     8521 ggactgctgt gataattagt cccgctatgg gaataatgac cgaatcgtta atgcttttaa
     8581 taaaggtaaa tacatctcca ttccacccca taggagtttt tcctacatct gttgcaactg
     8641 caccaacctt gtcgttgatg tcaagaaaca tggactctaa gtttgcttgg ataccgccca
     8701 gtagaagctc cttaaagaat tcttctattt tgtcgaatat cccaaacatc taagctctcc
     8761 ttttcttctt atctgagtac atttgcaaga agtggaatca gcttaagtcc gataaggaca
     8821 atacctcctc ccgccatcaa ttgcttgatc ccttgacttt tggctcccgg attatcgtta
     8881 ccataacctt ccatcaggtt aatgacaccc catgctccaa gtcctgctcc tactgccata
     8941 accaaaatct ttaatacatt tactgcctgt gcgaaaaatt ccataattta ttcctcctca
     9001 ttttcttctt tcttttcaat cttgttgtat gacttcacta caaaattttt gtaagtcttt
     9061 ccctcttttt cacgcttctt aaagtagccg aatacatgaa tcaaatcgcc cttttcaaag
     9121 tcctttgctt tatccgcttt ttctccatag gctgcacaat tgatgtactc cttgccttta
     9181 ccgtacttct ttacaagcgt aaaatttaca acttctactt ctttaccctc tttttcaaaa
     9241 cttgagaaag taggttctgc cactaagttg gcgttgatgt taatcatttc ttgcttcatt
     9301 aaaaatttct ccttttcatt tcaataaaaa aagcgaccgg aagtattact tttccaatcg
     9361 ctatactcat actatttagt tttttactca gtgggacttc tgatccttat catcttgcct
     9421 ccttactttt gcataaaaaa gcagcaaatc tattttgtag acttactgca ttcttgtaat
     9481 aactgtttcc ctattcagtt ttgcttttcc tttccgtttc atgtagcttt ctatatcaaa
     9541 taaatttttc ttatcatagt cctcaagcag cttatagttc ttgtgctttg taatatcgta
     9601 cttatctgaa agaaaaggtc tgacacctct aagctgaaag atacattttc caccatccat
     9661 gaccgtaatc tcatcctgac tcatcagctc tttgcctgtt ttttgatagt taagtccaaa
     9721 gctcttttga tttgaccttg tttccgatgt gttgtaaagg tcgatagttt ctttaccaag
     9781 cgtttcggac agctctttta gtgttttttt cctttccacc taagaataag gtactatcac
     9841 agttacccac aatggtatca gcattatcct tatatattgc ctttagctga gattgtgcct
     9901 gtaagataat actcgctgaa atttctctac ttctaattgt ggctatgagc ttctcaaact
     9961 ttggaattaa gccgatattt gcaaactcat caagtaagca tcttacatga acaggaagtc
    10021 tgccaccata tacatcatcc gccttatcgc aaagtagatt aaataactgt gaatacataa
    10081 tagacactac aaagttaaag gtatcatctg tatcagagat aataacaaag agtgctgtct
    10141 ttctatctcc caatgtatca agctcaagtt cgtcttcact catcaaatct ctaagttcct
    10201 gaatatcaaa tggagcaagc cttgcaccac aagatataag aatagatttt gctgtctttc
    10261 ccgcagccaa tttatatttt ttatattgct tgaccgcaaa gtgcgtaggc tcctttttct
    10321 caagtgcttc aaagagtctg tctattggat tcatataggt ttcatcatct tctcttactt
    10381 ctgaagcgtc tatcatatca aggagcgttg caaagttctt ttcttctctt ggagcttcat
    10441 agaagatata tccgataagt gctgtgtagt agagtttttc cgctttgacc caaaaatctt
    10501 cacccgcttt ttctccctca ccttttgtat ttgcaatgat tgtctgcact aatttgagta
    10561 tatctttctc agaatggata taggcaaagg gattgtattt catgctcttt ttgaagttta
    10621 tggtatttag aatttttatc tcatatccat tgtcttcaag catcttgcca cattcaatga
    10681 ctatcgttcc tttcggatcg gttacgcaat agctactgtg catctgcata aggttcggtt
    10741 ttacataaaa tcttgtctta ccacttcctg atccaccgat tacaagtaca ttcttgttac
    10801 gagcatactt tggattagcc ggtctaccat tcatagttag gcgttctgtc tgggtaagca
    10861 agatattgtt ttgaaacttt tcatccatgt atggctcaat atctttctta tttccccatc
    10921 ttgctgagcc atactctttc ccctgtctaa actttttagc attttacctt tggtatagac
    10981 aataaattta attaaagcag ccattcctat gcccattaaa atatccgccg gatgaatact
    11041 tggaagaaaa ctcatcgtgt tgatctccaa tatcccttga aagattttat ctatgacatc
    11101 accaccggta tagcttctca catgatgggc aaagatgttt cctaaataga aaaatgcaag
    11161 atagggaatg ttttgcttta caaactttgt cttatcctgc accttaaata agcctttgat
    11221 gtcctttaat attttatcta tcataggctc tgctcctttt gtttattctt gattttatct
    11281 ttggaaacag agttcttagc catttcctta aacttctcaa tattcttgtg aatagattct
    11341 ttcctttccg ttttcttttc agactgtgct aatgcgtgct taaaggcttt atccatcact
    11401 ttcatatctt tggcttgaaa gaatacagag tattttcctg tttccttatc cttcatcact
    11461 gaaaacttaa caccataccg attaagttct tttttcagtt ccttaagctc cgcttcttca
    11521 acaggaattt cttcaagctg tccctttttt accatatctt ttagctttac ttcatttccg
    11581 ttagcattaa ccagcttttc aagtcctcca agtttttctg cttctttcat caatttcttt
    11641 aataagttca gaattaactt tcctgttact ttagcagctc ttacttccat attcagcgtt
    11701 tttcttgcta tttcttcatt gatcaagttc tctcacctcc attcagtaac ctatctttat
    11761 ttcgattcaa tttatctctt tgaataatct ttctaaaatc ctctttggat tgtgtcgtag
    11821 gaaaggttag tggtgaagat agtcggtttc tgctttaagt acctgttgtt gacaatgtta
    11881 tatacctgct ctttggcata gcttgtatct ctttctattc ccaagtcatc caagataaga
    11941 acggaagtat ttacaaggga ttcaatatat gcgttcttat caaaatcaaa tcctcccttt
    12001 tgcagctcat tgataagctg tgcaaaattt cttattttaa cgcctatttg atactgttca
    12061 ataaggctat ttgcaatgga gcaggcaaga taggtttttc cacttcctac tgagccgtaa
    12121 aatagcagtc cgatattttc ttttttcatc tgctcatagt cttttacaaa attctttgca
    12181 atgataagac tttgattttc ttctccctga taattttcaa aggtgtatga ccactgaata
    12241 atagagttaa agcagttctt ttttaatcgt tctatttcca tctgcttttc tctttctttt
    12301 tttcttgcct ctctatctct atcgcatttg caagaaatct taaatatcat cttgttatca
    12361 aagaactcca tcacttttct gtcttttctt tcatgacaaa ctttacaaaa ggcgtgtccg
    12421 tccttgatat attctttttc aggatcgtaa gaatactcta catcctctat cattactttt
    12481 tctaattctt ttatcatagg tgttctcctt tatcatattc ttcccatgtc gggatatttg
    12541 atgttttcac ttctttgccc cttccctgat ctttataaaa ccatgaaagg attgttgcct
    12601 tatggtcttt ataggtcttt ccggtgcttt taatatatgc agataatctc tcaatataat
    12661 tatcaagctg tgagttcatt atgatttgta agtctgatat atcttcagca gctaaaaaca
    12721 cattttgaaa tgttccaagc ccgttttcac taaaattata ttctctctta ctatacttac
    12781 tcttattatt ctctatatag ttagagtcaa ggttcttaac ctcttgaagt tcattttctt
    12841 tacttctgag gttaaaatct tttacttctg aagtaaaatt ttttaacttc tgtaagtcat
    12901 cttcttttac ctgaaatatg ctcataaaat ctttgacata aatgatattc ggctttccaa
    12961 gtccaagccg tacccgttca atcagtccaa ttcctttttt actatctaat tcatctaatg
    13021 tttttatggc agtcggcttt gagatatttc ttcttttcat aatttcttcg actgtgaaat
    13081 agataaatac cctgccttcc ttatcaatcc agttattctt aaaggacatt cctgtccgtt
    13141 taagaagcat tgaataaagg ataattgctt cagcggataa tcctttaaat tcttctccat
    13201 caaccaatat ctccggtact tttaagaaat taaatctttc cgcttctctg ttataaaaat
    13261 agtcaaagtc catcgcttca cctccctcct taaaaatttg caaagaaaaa gacgatagtt
    13321 tttctctatc gcctttggta accattttta tgaaattttt tagattgatt ttattgcttc
    13381 attgattcct ttaaagaatg ctataactgc tgctccaacc atcggtattc cataaggact
    13441 taacaaaaat cctaatacta atgcctcaat gccaagtgat atatcttttt gcataaatga
    13501 tcctattgca gcaactatac acatcagcat taagaaatac agaatagttg ttcctatgcc
    13561 aagtataaat gtcagaaagg cagtaaggac actaagtagc aagctgaatg gaaacaatat
    13621 tatttttatt atccacctca tataatacct ctcctttctc ttaaatcatt ttaaagtgcc
    13681 ttaacgcatc cataatagct ttttctttct caggtgtaca ctgcggaata acttgcttat
    13741 ctttttttga tttattgtaa ttctctctaa gttctattcc acattttctt tttatctgtg
    13801 ctatatatag tgttgaaact ttaaaaccaa atttttctaa tatatactct ttaattttag
    13861 cataggtagc cttgctttct gcacttgtca aatcaagttc atcaagctct atttcaacac
    13921 ttatatactt atcgacatta agtttggaca ataatgctac cgtctcgaca tgatgtgtca
    13981 ttggaaacaa gtctactggc tggactttct ggagtttata gccgagttcc tcgtagcgct
    14041 tgatgtcacg cgccatggtg gcggggttgc aggatatata ggttattttg tcaggctgca
    14101 tcgctgcact ggccttgata aagctctcag ttagtccctt tcgtgggggg tctacaatga
    14161 taactgttgg ctttatgccc tcctgacacc agtttgccat cgcattttca gcgctgtcag
    14221 cgacatagta ggcattggta ataccgttta gcgctgcatt tttctcggca tcacgcactg
    14281 ctgcttcgat cacttcgaca ccgtatactg ctttgacttc tttagcaaag gatagcccga
    14341 tggttccaat gcctgaatag gcatcaatca ccacatcgtc agcggtcaat tcagaaaaat
    14401 caatagctgt ttgatagagc ttttcagcca ttgttgtatt gacctgatag aaggactgag
    14461 cagaaataca gtattgattg cccaagatcg tatctgtgat tgtctctttt ccataaagcc
    14521 ttgtaaacgc cttaccaaag ataacattag taggcttgtc attgatattt tgcaggatag
    14581 aagtaatcgc tggaaattct gcgacaaggc tatcaatcat ctggttgata cgaaagattt
    14641 taggtcgtgt tgtcactaaa accagcatga tttctcctga ataatgccca cgacgaacca
    14701 caagatgacg aatcaggcct gactgctcct tttcgtcata gggcttgatg tcaaaacggc
    14761 gcaaaaggtc gcgtgtaaag gcaatcaagc gatcaatttc cttatcttga atgtaaaaat
    14821 cagaaatcgg cactagctca tgagaatgct tacggaaaaa accagtctct agctgaccat
    14881 tgacacgacg aacaggaacc tgggctttat ttcgataagc ataaggatat tccataccaa
    14941 ttgtttcttt gacctcaaca ttgctaatcc ctgcaatctt atagagacta tcctgaacct
    15001 gcttttgctt aaagagcagc tgctgcggat aaagcaagtg ccccaaatca gcaatacctg
    15061 tacgcagata ggtcacatcc agcttttttt gacgcatcgg tgaggttgtt agataggtct
    15121 ctaccttgcc aaagccactg tttttattga cctttaggac acgcatctga atgatctcac
    15181 ctggaagagc attttcaaca aagaaaacaa agccttcatg cttagcgatt cctaagccat
    15241 catggcttaa atcagaaatt tccacctgaa caatatcgtt tttacttaac atttactttc
    15301 cttttctttt actacactaa tcactcaaaa aagaagagca accatcgtta cccttcatta
    15361 tagcatatct tagcgtaatc ccagcttaga taatcgattt tgatacttag caaaatcaat
    15421 aaagagagcc tgaccaccat acatgtcata ttcatcaatc caatccccat tttcaggaat
    15481 cgtcacatgc tccacaccgt ttttgccatt agtcaagacg gacactccat ttttaaggac
    15541 aaatgggaag gagacattgg ttgaggttag ggcataaatc ttaccaatag ctgctgagcc
    15601 cgtaaagagc ttggttggat ccttgatttg agacatgata gcagccatca cctgctgctg
    15661 acgtacggtc cgaccaaaat caccctcatc gtcctttcgg aagcgagcat agttgagcag
    15721 ggtacgacca tccatttttt gctcaccaac cgttatggtt tggttgggaa ccactccgtc
    15781 tttcattcgt aaatcatctg gtacatcaac agcagcgact gcttcgccat ttacagtagc
    15841 aaatttggca tcaatggtaa caccatctgg aaacagtgtg tcaatagcct cagcaaaggt
    15901 ttcaaagtca accatgacat aatatttaat gtcaatatca aaattatgct tgagtgtctg
    15961 acgcacaaat tctgctcctt gatgattttc ctgctctcct aaattaaagg aggcgttcaa
    16021 ttttaaatca taggaatcct gattattata gctatagcca ggaatattaa ccaaggtatc
    16081 cctcatgaag gagaccattt tgattttatt ctccttattg ccaacattaa ccaccatgat
    16141 tgtatctgtt cgagcatctg ttgagccttg cgtaatcctc tggtctgagc ctagaattaa
    16201 aatattagtg ccatcgctag tatcctgacc atgaaagacc tgcgaaactg ctggcttata
    16261 attggccttg ttagtagaca cgtccatcat tcccttgaaa aacatgaaag ctatccctgc
    16321 aacaagcagc agcaacaaga aaaagagtat tctgaaaaaa cgtctcagac gtcccttctt
    16381 ttttttcctt ctaccctttt taggcatagc ctcaggcgca agctcctcat agatcgcctg
    16441 atctgggtca tcatagaagt cctgctgagg ggctagtatt ggcttttgct gatgcctttt
    16501 gctacgtctt tctgatcttg gataaagagg caggccatta ggcccagcct gctgctcatc
    16561 actcatatca taagcatcag cattatcctg tgaagcttga gcataatcgt cacgcccacc
    16621 cctagtataa tgagtcaagg agcgctgaga acgagaaggc atagcccttg actccatctt
    16681 tgactttaaa aaggtaaatt ctctgcgttc agtctcagtc aaataattta aatttcttaa
    16741 taaataaaaa tatcgtaatt cttcgtggtg gcttagacca cccttttggt atctcgtcat
    16801 gctcttccaa ctcttagtat tctaatacaa tttcttctat tctttgtcta atgattctat
    16861 tataacctat attaacgaga ttgtcctcta aaatcgttag aattcaactt tatttcaacc
    16921 tatatattag cttttcatac ctaatcatta agaaaagctg ggctgcgaat aggaggccaa
    16981 aagtctaatc ctcagcagtt acgacatatt ggcaatgatt gctgcaacct cctttggtgt
    17041 tctatgctca acattaatca ctttgtctgc caatccctca tacaaggcca tgcgctgctg
    17101 aaaaatagca tagagttctg cttcagaatg atttaaaaac agtggtcttt ggcatagcct
    17161 atctttttta agccgatcat acaaagcctc aaaggaggct gttaagagga tattattttt
    17221 gtgatttttt ctgattaatt ctcggtttgc cttactaagg acaacacctc caccagttga
    17281 tacgatagtc tcattatcaa gtgccagcac ttcctgtaag gtatctgact caagctttct
    17341 aaaggctgct tcaccacgat aggaaaaaaa tgctgatatg ctcatgccta ttttagcctc
    17401 aataagccta tccatatcca aaaaatgctc atctaattgg gctgcaactg tcgtcttgcc
    17461 aactcccata aatcctaata gcagcttagt catgccataa cctctctaaa tccttaaaaa
    17521 agtcaggata agaagtcagg atagcttctg ctcgctctag ggtgacctgt ccttcttcaa
    17581 ccagtagggc tgcaatagct gtcatcatgc caattctatg atctccacag gtactgacag
    17641 ctgcaccatg taatggtgtt ttgcctctag tcaccatacc gtcctctgtc gcctgaatat
    17701 cagcacccat ctgtcctaat acatcagtaa cagcctgaat gcggtcagtt tccttgaccc
    17761 gtaattcttg agcgtccctg atataagtcg ttccctgtgc ctgagttgcc agcaaagcaa
    17821 taacaggcaa ttcgtcaatc aagcgaggaa tcaagtcacc agaaatctca atgcccttta
    17881 gggtggaata agacactttt agggtagcag cctgcctgtc cttatcaaca gcctgatagg
    17941 agatacgacc acccattttt tcaatgacct ctaaaagacc tgtccgcgta ggattaatcc
    18001 ctacattttc gagcacaaga tctgaccccg gaacaatcag accagcagct aaccaaaagg
    18061 ctgcgctaga gagatcgcca ggaatctgta aggtctgtcc ctgcaaacgc tgcggtcctt
    18121 tgatactgat ttgctttcca gctactgaga gctttcctcc aaattgttca atcatctctt
    18181 cggtatgatt tcttgtcaat tccttttcaa ggataacagt ctctccctgt gtctgcaaag
    18241 cagctaataa aatagcagac ttgacctgag cagacgctac aggcagctga taatggatcg
    18301 gccgcaactc ctgacagccc tttacaatta gtggtggaag ctctttttct ccttgaccag
    18361 atagctctgc tcccattaga gacaatggta tggtaatacg atccatagga cgccttgata
    18421 ggctatcatc tccaagcagc tgcaccgaaa aatcctgtgc tgctaatagc cctgcaagca
    18481 ggcgcataga agtacctgaa ttgcccatgt ctagaggctt ttgagctggc tttaggcctt
    18541 taaaacctct tccttcaatg attaaactat cagctgactc gtaaatggtg acacctaggt
    18601 ctcgaaaggc ttgaatggtg gctaaaacat cttgccccct taaaagacca tgaatcaccg
    18661 tttgcccctc tgctatagca ccaaaaatga ctgcacgatg gctaattgac ttgtcacctg
    18721 gtacccttag acgtccccta agcgccttag cttttgtttt taatttcatc attactccta
    18781 tttttagtac accagcatta gctcagcaaa gcaaataaaa gaaaatgaag taaggacaag
    18841 ggcccttacc ccatcaacta atcaccaagc accgtcttgt ttttcattct aagacaagcc
    18901 gctatttctt gggcggcgca ccatcattgc ctaatgtctt tttgatgaga gaaacaacat
    18961 tgccgctgcg cccctctaat ttgccgatgg atagctcttg ataggtagcg ttaaaaaccg
    19021 cccccataat caatatcctt gccaggaaaa taaaccatag catgatgata aaaatcatca
    19081 ccgaaccaaa ggttttaata tcgaccattc gctccacatt atgcaccaca taattaccaa
    19141 ccatattgct caaaaaaatc atgacaaagg tggtaaaaaa tgttcctggt aagatatacc
    19201 tgattttctt gattttgata tttggcaaca aaaaataaag caacatcaga ccaacaaata
    19261 taatcagtat cgtaatcggc tgaatcagga acaaaaagag cgtcgtgatg ttatcattta
    19321 agtgataatg cctatccagc acctgaatcg ctgccttaga aaaggttgaa aaaatcaagg
    19381 caaaggtcaa caaaaacagg atcagcaggc tcgtcagcaa gcctaccaaa tgaccgagca
    19441 aaaagtcacg atgctcagaa gcatcataag ccttattaaa ggccttttgc agagaggtta
    19501 ggcttcgcga cattgtccaa agccccgtca aggtcgctac tcccagcaca ctgcctgatg
    19561 gcttagaaaa aatattaacc acaatggagg aggcagagcg ataaatatcc ttaggcagct
    19621 gctccttcat taagcgtaat aaatctgaaa tatcaatatt taaataagga aaaatattag
    19681 ccgcaatgac aatgagtgga aaggctgtca aaataaggta ataagcaact gcaatcgctg
    19741 acaaatccat ctctgcactc tgaaaatggc gcataaaggc ttggattggc tcatattgcc
    19801 attttgatat gaccttgtcc aagaatttct ttattgacat tctaataagt tctttcttcg
    19861 ccctgactag ttaaaatcac tggaccatcc tttgtaatca caaattgatg ctcatactgg
    19921 caggacaagc caccatcaag tgttttatgg gcccagcctg ttttcatatc tgtattaatt
    19981 tcccatgtgc cagtattgat catcggctct acggtgagca ccatgccctc cttcagacgt
    20041 agtcctcttc ctgctgtacc atagttaggc accatcggct cttcgtgcat ggttggtcca
    20101 acaccatgac caacaaggtc tcgaaccaca ccgtagccat gactttcagc atattgctgg
    20161 actgctgcac caatgtcacc aatgcggttc cccacaactg cctgctcgat cccacgatac
    20221 atggcttcct tggtcacgtc catcagcctt ttgacctcat cagacggtgt acctacagca
    20281 taagcccagc aggaatcagc caaaccacct gtataagatt ctgtccactt cttcatttct
    20341 gccacattat caaaatccaa ggccgctaca tcaacgacag ccttatcaag tggctcactt
    20401 agcaccatat ctaccttaag caaatcccct tcctgtagaa tataatggcg cggaaaagca
    20461 tgtgcaacct catcatttag cccgcagcag gtagcgtaag gataatccat taattggcca
    20521 tcaacaccga tctgtaaagg aagcacattg tcctccttgc agcgcctgcg cacatattct
    20581 tcgacctccc acatgtcaac cccaggctta atgatctgtc tgaggccaat gtgaatccca
    20641 gcaagaaagt ctcctgctct atccatagct tctatttcac gcgcagattt taatgttatc
    20701 attgtttttg tttctcctct aattaagctt agttgtaata atggctttag caatcacctg
    20761 atcatcaacc atgacctcca tatcaagtgt actgcttctt ctattttcag ttataatttt
    20821 agggtatatc ctcaattgat catcaatttg gacagcatgt agaaagtata tcatcatttg
    20881 ctcgataatg atattttttt ggtgtttttt cgttagcact ctgacactga tttcctttaa
    20941 gaattcagca accactccat ttgacagatt gccagcacta tcaatcatgg taggctcaat
    21001 catgacctga taataatcca aggtctcctc aaggcttgat agcatttgct ggctataggt
    21061 gtaaagattt cccggctggt gattcggcag gttttccata gcctgtcgtc tggtaataat
    21121 ccccagcaga aaatgatgat catcaactac tgggagcatg ttcaaatcct caaagatcat
    21181 tttttgacta atattagcca ggctagcatt gggctttgca gtgataggat ttggagacat
    21241 cacctgctca agtctagtct cagcaggctg atccaccaca tcacgcatac tgaccacacc
    21301 aaccacctga tcaagcgcat ctacaattgg aaaccttact tgacctgtct ttttaatcag
    21361 tgcattaaat tcctcgacag tgtctgtctc ataaaggcag ccgtattctt caactggaat
    21421 cagaacctga gcaactgttt ttaaatcagt cttaatgcga atattagaca aggcatggtt
    21481 aatcatcgtt gccactgtaa aggtatcgta atgtgtcacc ataaccggaa taccttggct
    21541 atcagctgtt tcaataacct gcttagacac cggaaagcca cccgtcacta agatagcatt
    21601 gtgattttta agggctaaca gttggatatt ttcacgatcg ccaacaatca aaagccctcc
    21661 tttgatcaaa taacggtgaa tattttgctg ggtcatcgct ccaatagaaa acttgctaaa
    21721 ctcatgtccc aaaccagcat gaccggctaa aacctcagaa tcactgatcc ttgcaatttc
    21781 ggcataggtc aaacggtcaa tacgaacccg tccttttttc tcaatgcgga cagtaccact
    21841 acgcggcttg gtctcaacaa tcccccgatt ttcagcctcc ttgatcgctc tataggcagt
    21901 accatcacta acctttaaat gatttgaaat acttcggacg ctcacacgct ttccaatagc
    21961 aagtctttct aaataatcta aaatgtcttg atgcttactc ataatgatac tcacctatcg
    22021 ttagttgata ttctaaataa tctcgtatgt gatgactatg ccgatcactg cccttaaatt
    22081 gctttgttaa tcgaaagccg gctttttcag caaccctctg gctggccttg ttttccagat
    22141 gtgtcacaat gatcagctgc ctcaagccaa actcctgaaa agctaaaaag gtaagcgtct
    22201 ttaagacctc ggtcattaag ccctgtcccc aaaagggctg cgctaaaaaa tagccaatct
    22261 cagcacttgc ctgctgctta tcatattttt ctagtctaat agagccaagc atgctatggc
    22321 tggtcttatc ctctattaac cagactccca agggctcttt cataaaagca ttgaccatta
    22381 agaaatcact ctcagccttg gtcatgctct ctggaaacac aaactggtaa tggctgttat
    22441 gactgatcat atcataaaac ggctgatgat ctgcatattg aaagggcctc aagagcagtc
    22501 gttgcgtctc aacaaaagca aaccttgcta gctgtgtcca aatatccata gcctcccctt
    22561 caacatgcct gtaatactat tattatagca gatatcacct aaacattcta taactgtcat
    22621 gagttttgcc atgatgatca taataacctg acaagccata tcatagctca atcagactct
    22681 aagctgttaa actattacta acagtcaaaa ccaaaaaaga gaagaccgtc tgatcttctc
    22741 ttgctatctt atctgctaat gcttaaatgg gctacatcat agaaaagtcc tatgagtaag
    22801 ctcatccttc taaggctaaa catgcttcca taaatacact gcttagtcct gctgacgctt
    22861 tgaagtcact gctaaagcac ctgcactcgc cataatggca agagccgctg ctgtaaagaa
    22921 tggattagcc ttctcaccag tcgttggaag agtcttagcc ttttgcttat ctttttgctt
    22981 agctggtgct gtcttagttg ctggtgtaag cggtgtcaac ggaagagaag ctgatggctt
    23041 ttctggatca gctggactct cctctaaagc ctcagtgact gtaaatgtct ttgtagcagc
    23101 gtcataagcc cattcaccag taacgccatt gtcattggca tattgcctga aggtctgctc
    23161 ggctgtggct gcgtctactg ccttggtagc tgtttcacct gagaaggtaa cccccttaat
    23221 aacaagccta taggtggtca aagctggtgt taattctgcc gcctcaatag tctcagctac
    23281 aggctgttca gtgactgtaa atgtctttgt ggcagcatca taagcccaaa cgccgtctac
    23341 accattttta ttagcatagt ctctgaaggt ctgctcagct acagctgcgt ctactgcctt
    23401 agtagctgtt tcacctgaaa aagttgctcc cttgatgaca agcttatagc tagtcaaggc
    23461 tggtgttagt tctgctgcgt caatgacctc agaactcggt agagctgata aaatctctgc
    23521 cttaagcgca ttgacacctt caacagtttt ggctttgttg attaaggtca catagtaatc
    23581 actaatgcca tactgcttta gttcattgat agcagcttct ttagcctcca acaaggctgc
    23641 tcctgtaatg tccgcaatag ctgtatgagc atcattaatg gctgcattca cttgatcaac
    23701 tgaagcagca tctgccacct tagctgctgc agcaactaga gctagctgaa ccttttgatc
    23761 gcttttgtgc tgatcactta aggcattgat tgttctgtaa gcctcacgtc ttgcttcatc
    23821 aagctgaaca ccagcaacag ctgcctttgc tttgtcaaga gctgctttag cctgatcaac
    23881 agtatctgca gcaagtgcct caactccagc attagcaaga acagcctgaa gctcttgatt
    23941 gtcagcgtag tcatcactca gctgattgat ttccctaaca gcttctctaa tgaaggctgt
    24001 tgtaggctct aacactgttg ctgcgtctaa agcacccact gaagtcgttc caaccagaaa
    24061 ggctgccgac actgaagcta aaccaacagc tgattgacgt aaaaagtagg ataccttttt
    24121 gtttttttcc atttttcctc cctcgctttt tgtaaaaaaa actttgacac taaaaactat
    24181 taatgtca
//
LOCUS       DARYLJ010000036        22717 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYLJ010000036 DARYLJ010000000
VERSION     DARYLJ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22717
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            524..2008
                     /locus_tag="TU746_001364"
     CDS             524..2008
                     /locus_tag="TU746_001364"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL0891705.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            2048..3349
                     /locus_tag="TU746_001365"
     CDS             2048..3349
                     /locus_tag="TU746_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL0891706.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            3729..4037
                     /gene="rpsJ"
                     /locus_tag="TU746_001366"
     CDS             3729..4037
                     /gene="rpsJ"
                     /locus_tag="TU746_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL0891707.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPFPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            4335..4961
                     /gene="rplC"
                     /locus_tag="TU746_001367"
     CDS             4335..4961
                     /gene="rplC"
                     /locus_tag="TU746_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL0891708.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            4986..5609
                     /gene="rplD"
                     /locus_tag="TU746_001368"
     CDS             4986..5609
                     /gene="rplD"
                     /locus_tag="TU746_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL0891709.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            5609..5905
                     /locus_tag="TU746_001369"
     CDS             5609..5905
                     /locus_tag="TU746_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL0891710.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            5923..6756
                     /gene="rplB"
                     /locus_tag="TU746_001370"
     CDS             5923..6756
                     /gene="rplB"
                     /locus_tag="TU746_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL0891711.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            6868..7146
                     /gene="rpsS"
                     /locus_tag="TU746_001371"
     CDS             6868..7146
                     /gene="rpsS"
                     /locus_tag="TU746_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL0891712.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7162..7506
                     /gene="rplV"
                     /locus_tag="TU746_001372"
     CDS             7162..7506
                     /gene="rplV"
                     /locus_tag="TU746_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL0891713.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            7519..8172
                     /gene="rpsC"
                     /locus_tag="TU746_001373"
     CDS             7519..8172
                     /gene="rpsC"
                     /locus_tag="TU746_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL0891714.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8176..8589
                     /gene="rplP"
                     /locus_tag="TU746_001374"
     CDS             8176..8589
                     /gene="rplP"
                     /locus_tag="TU746_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL0891715.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            8599..8805
                     /locus_tag="TU746_001375"
     CDS             8599..8805
                     /locus_tag="TU746_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL0891716.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            8830..9093
                     /gene="rpsQ"
                     /locus_tag="TU746_001376"
     CDS             8830..9093
                     /gene="rpsQ"
                     /locus_tag="TU746_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL0891717.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9118..9486
                     /gene="rplN"
                     /locus_tag="TU746_001377"
     CDS             9118..9486
                     /gene="rplN"
                     /locus_tag="TU746_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL0891718.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            9570..9875
                     /gene="rplX"
                     /locus_tag="TU746_001378"
     CDS             9570..9875
                     /gene="rplX"
                     /locus_tag="TU746_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL0891719.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            9899..10441
                     /gene="rplE"
                     /locus_tag="TU746_001379"
     CDS             9899..10441
                     /gene="rplE"
                     /locus_tag="TU746_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL0891720.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            10457..10642
                     /locus_tag="TU746_001380"
     CDS             10457..10642
                     /locus_tag="TU746_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL0891721.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            10975..11373
                     /gene="rpsH"
                     /locus_tag="TU746_001381"
     CDS             10975..11373
                     /gene="rpsH"
                     /locus_tag="TU746_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL0891722.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            11695..12231
                     /gene="rplF"
                     /locus_tag="TU746_001382"
     CDS             11695..12231
                     /gene="rplF"
                     /locus_tag="TU746_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL0891723.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            12334..12690
                     /gene="rplR"
                     /locus_tag="TU746_001383"
     CDS             12334..12690
                     /gene="rplR"
                     /locus_tag="TU746_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL0891724.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            12709..13203
                     /gene="rpsE"
                     /locus_tag="TU746_001384"
     CDS             12709..13203
                     /gene="rpsE"
                     /locus_tag="TU746_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL0891725.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13218..13400
                     /gene="rpmD"
                     /locus_tag="TU746_001385"
     CDS             13218..13400
                     /gene="rpmD"
                     /locus_tag="TU746_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL0891726.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            13602..14042
                     /gene="rplO"
                     /locus_tag="TU746_001386"
     CDS             13602..14042
                     /gene="rplO"
                     /locus_tag="TU746_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL0891727.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            14059..15363
                     /gene="secY"
                     /locus_tag="TU746_001387"
     CDS             14059..15363
                     /gene="secY"
                     /locus_tag="TU746_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL0891728.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            15515..16156
                     /locus_tag="TU746_001388"
     CDS             15515..16156
                     /locus_tag="TU746_001388"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL0891729.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16274..16492
                     /gene="infA"
                     /locus_tag="TU746_001389"
     CDS             16274..16492
                     /gene="infA"
                     /locus_tag="TU746_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL0891730.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            16518..16634
                     /gene="rpmJ"
                     /locus_tag="TU746_001390"
     CDS             16518..16634
                     /gene="rpmJ"
                     /locus_tag="TU746_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL0891731.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            16652..17017
                     /gene="rpsM"
                     /locus_tag="TU746_001391"
     CDS             16652..17017
                     /gene="rpsM"
                     /locus_tag="TU746_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL0891732.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            17035..17418
                     /gene="rpsK"
                     /locus_tag="TU746_001392"
     CDS             17035..17418
                     /gene="rpsK"
                     /locus_tag="TU746_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL0891733.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            17465..18403
                     /locus_tag="TU746_001393"
     CDS             17465..18403
                     /locus_tag="TU746_001393"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL0891734.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            18418..18804
                     /gene="rplQ"
                     /locus_tag="TU746_001394"
     CDS             18418..18804
                     /gene="rplQ"
                     /locus_tag="TU746_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL0891735.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(19022..19253)
                     /locus_tag="TU746_001395"
                     /pseudo
     CDS             complement(19022..19253)
                     /locus_tag="TU746_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20109..21359
                     /locus_tag="TU746_001396"
     CDS             20109..21359
                     /locus_tag="TU746_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891736.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            21349..22224
                     /locus_tag="TU746_001397"
                     /pseudo
     CDS             21349..22224
                     /locus_tag="TU746_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22245..22538
                     /locus_tag="TU746_001398"
     CDS             22245..22538
                     /locus_tag="TU746_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0891737.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT         7000 a         4073 c         5039 g         6605 t
ORIGIN      
        1 aatttttgta gattgcatga agtataatgc ctataagttt ttagtactca attttatgat
       61 ttaatattta aattaagcaa tagtcaagtc acctttcact aagaaaaatc acttgattat
      121 tgcttagttt tttctaatgg aggattttta gtttagaagc tttgagttta gacctcaaaa
      181 cttagatatg gaattcgaaa ggcagtcact gctgtcaaca ttactttggg aaagttccta
      241 taagagactt ttcattagac tgaagtagct tcaatagctc taaaactacc tagactcaag
      301 taacaacaag tccttagaat tgattttcta agggcttttt tgctgcctca aggtaaagac
      361 atgttcagca acaaattgac tggctagacc agtcctttat ttatgctgat ggcttgagac
      421 tgctgggtta ttagcacaga aaatggctgt ctccaaatcc tagaaggctt atgattggaa
      481 tatgatataa tagtcaaaag aaatgatgag gtgatgtgaa gcaatgccaa tgatgtacca
      541 atcaacaaga aatgcagcta ataaggtaac agctagtcaa gcgattttaa gtggcctagc
      601 agatgatggt ggcttgttta ctcctacaag catgccagtg ctggatctag attttgagga
      661 gctaaagacc aagtcctatc aagaggttgc caagcttatt ttatcagcct tttttgatga
      721 ctatactgaa gcagaattag atgcttgtat ctcttctgcc tatgatgata agtttgatac
      781 agcagtgata gcacctctag ctacgttaaa ggattatcat aatttggagc tatttcatgg
      841 ctcaaccatc gcatttaagg acatggctct atctattttg ccttatctct tgacaactgc
      901 tgctaaaaag caaggtgtgg agcgaaaaat tgcgatttta accgctacct caggtgatac
      961 tggtaaggca gcaatggcag gctttgttga tgttccggga acggatatta ttgtctttta
     1021 tcctaagtca ggcgttagca ggattcagga gctgcagatg atcacacagg ccggtcacaa
     1081 tacccatgtt gtggcgattg aaggcaattt tgatgatgct caaacagagg tcaagcgcct
     1141 gtttaatgac cctgatttgc gtgagcggct agcagctcaa cagatacagc tgtcttcggc
     1201 caattcgatg aatattggtc gtttgattcc tcaggttgtc tattatattt atgcttatgc
     1261 ccagttggta aggcatcagc gacttgaagc tggagagacg attaacatag tagtgccgac
     1321 aggaaatttt ggcaatctac tggttgccta ctacgccaaa gaaattggac ttcctgttgc
     1381 caaattcatc tgtgcttcca atgaaaacaa tgtcttgaca gatttctttg ctagtggtag
     1441 gtatgataaa aagcgtccct tcaaggtgac tactagtcca tcaatggata ttttggtgtc
     1501 ttcaaattta gagcgcttgg ttttttattt actaggcaat gatgcccaaa agacagcagt
     1561 attaatgaag agcttggcag aaacaggtca gtatcagcta gctgatgcag atcagtctat
     1621 ccttgattta tttgcggcag gctttgcaac agagcaagag actgctaaag agatcaaaac
     1681 gatatttgag tctgatcatt atgtgcttga cccacataca gctgtagctt cagctgttta
     1741 tcgtgcttat cgggagcaat caggtgactc tagaccgact attgttgcgt caactgctag
     1801 tccttataag tttccgcggg tagttgtgga agctattagt ggtcagcagg ttgccagtga
     1861 ttttgaggcg cttgagcagt tggctgatat atcaggtgta gtcgtgccac aagcggtcaa
     1921 tggcttacag gaggcgccca ttcgtcatag ccttttagtg acagtagcag atatgcagca
     1981 ggcagtagag gcttatcttg gagtatagga ggcataaagg agctcccttt caattgatat
     2041 gaatataatg actcacaata gaaaaaagat actgtccttg gcccttccat caatggcaga
     2101 aaatatattg caaatgctga tgggaatgat agacaattat ttggctgctc aaattggact
     2161 tacggctgtt tcaggcattg cgattgctaa taatattctg acgatttatc aggccctttt
     2221 tatcgcatta ggtgctgcag tctccagtct cattgctaga agcgtaggag agcaaaacca
     2281 ttctaaagaa atcgactaca tggcaaatgc tatcttagta acgggggctc tatcagttct
     2341 tctaggcttg atgtccgtag tgggacataa aagcatatta gcctttctgg gagcagctag
     2401 tctggtagct agacttggtg ggcagtattt agccattgtc ggtggaatga ttcttagtct
     2461 tggtcttttc acgagcttag gtgcgattat tcgtgctaag ggccagccta gcattcccat
     2521 gaaggtcagc cttttaacta atttgctaaa cgctgtattt tcagcccttt ctctttacat
     2581 atggggattt ggagtgatag ggattgcttg gtcaactgtt gcatcacgtc tcattggagt
     2641 tgttattcta tgtcactttc ttcctattaa agaaattatt aaacgttttg ctaatccctt
     2701 agataaagag atctttagcc tctctcttcc agcggctggt gagcggctca tgatgcgagc
     2761 tggtgatgtg ctgattgtta ctattattgt tagatttgga acagaggcct tggcaggcaa
     2821 tgcgattgga gaaaccttaa ctcaatttaa ttatatgccg ggacttgcta tgtcaactgc
     2881 gacagtcatt ttagttgcca atcagttggg cagtggcaaa ggggctacaa tagcgaaaac
     2941 tgtaaaagaa acctttttgt tagccaccct gatgatgctt gttatgggct tgatcactta
     3001 tttgctaggc cctaatctac tgcccttatt tacagcagat gccaaggctc agcaggctgg
     3061 tatggttgtc ttagtctttt ctcttttggg ggtaccagca acagccggga ccttggttta
     3121 tacagcagcc tggcagggta tcggacaagc taagcttccc ttttatgcaa caacgattgg
     3181 tatgtggctg gttcggattt ctttgggcta ctttattgga gtaaccttaa attatggagt
     3241 aataggtgtt tggcttgcga ctattttgga caatgctacc agatggctca ttcttgcagt
     3301 ggcttttaag aagcagcaaa ggcagctttt ttcggactgt catagctaaa ctttgtattt
     3361 aggtctcaag acttctgagt ggtgactttc cttttgggag tcagccactg tcatcagaat
     3421 gtaaagtacg cctgaggctc tgtttgctaa tagcttctct tatctgcgga agatcaaaga
     3481 ggattgctgg aacagctgag gtttgtcttc aatctggctt gccctttctt agggcaagtt
     3541 tttttgaaaa aatcccctga aaggcttgca atgccttatt aattctgcta ttatattatg
     3601 gtgctgtaaa aatacagctt tagctgtgat acgagaggtt gcgacacgct cggttgcatt
     3661 gccacgtgac aggtgtcggt tttctcgagg agctagccta ttatcgtaaa tagacgagag
     3721 gagaaaagat ggcaaacaaa aaaatccgta tccgcttgaa agcgtacgaa caccgtacac
     3781 ttgatacagc ggcagaaaaa atcgttgaaa ctgcaactcg tacaggtgca acagtagctg
     3841 gaccagttcc atttccaact gaacgtagtc tttacaccat tattcgtgcg actcacaagt
     3901 ataaagattc tcgcgaacaa tttgaaatgc gtacacacaa acgtcttatt gatattgtga
     3961 acccaacgca aaagactgtt gatgcactta tgaaattgga ccttccaagt ggtgtcaacg
     4021 tagaaatcaa gctttaattg tttgaaacat gagtgaggaa cgagttcata tctaattgaa
     4081 cacaggctaa actctgtgtg aaaaagagac acagccgttc taattttaat tagattacgg
     4141 atgtggctac ctgtaggtgt aaatcttcct agaaacagaa gtttcttcgt cagatttcct
     4201 attttcactg tgagtttgac gccttaagta tcttgctttg agcataaaaa acgctcgtaa
     4261 aaaacttttt tgagcataaa aaacgctcac taaaaacttt ttgaaatatt attaagaaaa
     4321 ggaattattt tctcatgaca aaaggaatct taggggaaaa agtgggaatg actcaaatct
     4381 tcactgaatc cggtgaattt atccctgtta ctgtcatcga agcaactcca aacgttgtgc
     4441 ttcaagttaa gactgttgaa acagacggtt acgaagcaat tcaagttggt tttgatgata
     4501 aacgtgaagt attgagcaac aaacctgcca aaggccatgt agcaaaagct aacacagctc
     4561 ctaagcgctt cattcgtgaa ttcaaaaaca ttgaaggctt agaagtaggt gcagaaatca
     4621 ctgtggatat cttcgcagct ggggatgttg ttgatgtaac tggtacttca aaaggtaaag
     4681 gcttccaagg tgttatcaaa cgccatggtc aatcacgtgg tccgatggcc catggttctc
     4741 gttaccatcg tcgtccaggt tctatgggac ctgtttcacc aaaccgcgtt ttcaaaaaca
     4801 aacatttggc aggacgcatg ggtggcaatc gtgtaactat tcaaaatctt gaaattgtac
     4861 aagttatccc agaaaagaac gttattctta ttaaaggtaa cgtaccaggt gctaagaaat
     4921 ctcttatcac catcaaatca gcagttaaag ctgctaaata ataagaaagg agaaaacagt
     4981 taaaaatggc aaacgtaaaa ctatttgacc aaactggtaa agaagttagc acagttgaat
     5041 taaatgatga tatctttggt atcgaaccaa acgaatcagt tgtttttgat gttgtaatca
     5101 gccaacgtgc tagccttcgc caaggtactc atgcggttaa aaaccgttca gcagtatcag
     5161 gtggtggacg taaaccttgg cgtcaaaaag gaactggacg tgctcgtcaa ggttctatcc
     5221 gctcaccaca atggcgtggt ggtggtgttg tctttggacc aactccacgt tcatatggat
     5281 acaaacttcc acaaaaagtt cgtcgccttg ctttgaaatc agtttactca gcaaaagttg
     5341 ctgaagataa atttgtagct gtagaaagcc tttcatttgc agcaccaaaa acagctgaat
     5401 ttgcaaaggt gctttcagct cttagcattg atacaaaagt acttgttctt gttgaagaag
     5461 gaaatgaatt tgcagcactt tctgcacgta accttccaaa cgtagctgtg gcaacagcag
     5521 cgactgcaag tgttcttgat atcgtaaacg cagacaaact tcttgtaacg aaagaagcaa
     5581 tctctacaat tgaggaggtt cttgcataat gaatttgtac gacgtaatca aaaaaccagt
     5641 tattactgaa aaatcaatgt atgcccttga agaaggtaaa tacacatttg aagttgacac
     5701 acgtgcgcac aaactgttaa tcaagcaagc tgttgaagct gcatttgacg gagttaaggt
     5761 tgcaagcgtc aatactgtta acgttaaacc aaaggctaag cgtgttggtc gttacacagg
     5821 ttttacttca aaaactaaaa aggctatcat cactcttaca gctgattcta aagcaatcga
     5881 gttgttcgca gttgaagctg aataatctaa ggaggaaata acgtgggtat taaagtttat
     5941 aaaccaacga caaatggccg tcgtaacatg acttctttgg atttcgctga aatcacaaca
     6001 agcacacctg agaaatcatt gcttgtttct cttaaaaaca aagctggtcg taacaacaat
     6061 ggtcgcatta cagttcgtca ccaaggtggt ggacacaaac gccattaccg tttgattgac
     6121 ttcaagcgta acaaagatgg tgttgaagca gttgttaaaa caatcgaata cgatccaaac
     6181 cgtactgcaa acattgcact tgtacattac actgacggag ttaaggctta catcatcgct
     6241 cctaagggtc ttgaagtagg tcaacgtatt gtttctggac cagatgcaga tattaaggtt
     6301 ggtaatgcac ttccattagt aaacattcct gttggtacag ttgttcacaa cattgagctt
     6361 aagcctggta agggtggaga gcttgtacgt gctgctggag cttctgctca agtacttggt
     6421 caagaaggca aatacgttct tgttcgtctt caatcaggtg aagttcgtat gattcttgga
     6481 acatgtcgtg caactgttgg tacagttggt aacgagcaac aatcacttgt taacattggt
     6541 aaagcaggac gtagccgttg gaaaggtatc cgcccaacag ttcgtggttc tgtaatgaac
     6601 cctaacgatc acccacatgg tggtggtgaa ggtaaagcac cagttggacg taaagcgcca
     6661 tctactcctt ggggtaaacc agcgcttggt cttaaaacac gtaacaaaaa agctaaatct
     6721 aacaagcttc ttgttcgtcg tcgtaacgaa aaataagcgg caaatctagc ataagcttat
     6781 tcaatcattc cgccagctcg gtagagtttg agcttgctct catgctcaag ccgctgtggt
     6841 acattattta aaggagaaaa ctacaaaatg ggacgtagtc ttaaaaaagg acctttcgtc
     6901 gatgagcatt tgatgaaaaa agttgaagct caagctaatg acgaaaagaa aaaagtaatc
     6961 aaaacttggt cacgtcgttc aacgattttc ccaagtttca tcggatatac aatcgcagtt
     7021 tatgatggcc gcaagcatgt acctgtgtac attcaagaag acatggtagg tcacaagctt
     7081 ggtgaatttg caccaactcg tacctacaag ggtcacgcag ctgacgacaa gaaaacacgt
     7141 cgttaatagg aggaggacac aatggcagaa attacttcag ctaaagcaat ggctcgtaca
     7201 gtgcgtgttt cacctcgtaa aacacgttta gtacttgatc ttatccgcgg taagaaagtt
     7261 gctgatgcaa tcgcaatctt aaaattcact ccaaacaaag cagctcgtgt tattgagaaa
     7321 actcttaact cagcaattgc taacgcagaa aataactttg gtttggaaaa agctaacttg
     7381 gtagtatctg aaacatttgc aaacgaagga ccaacaatga aacgtttccg tccacgtgca
     7441 aagggctcag cgtcaccaat caacaagcga acaactcacg ttacagtagt tgtatcagaa
     7501 aaataaggag gtaaaatcgt gggtcaaaaa gtacatccaa ttggtatgcg tgtcggaatc
     7561 attcgtgact gggatgcaaa atggtatgct gaaaaagaat acgcggatta ccttcatgaa
     7621 gatcttgcaa tccgtaaatt cattaacaaa gaattggcag aggcttcagt ttcaacaatt
     7681 gaaattgagc gtgctgtaaa taaagttatt gtttcacttc acactgcaaa gcctggtatg
     7741 gttatcggta aaggtggagc aaatgttgac gctcttcgcg ctcagcttaa caaattaact
     7801 ggaaaacaag tacacatcaa catcatcgaa atcaaacagc ctgatcttga tgcccacctt
     7861 gttggtgaaa acattgctcg tcagcttgag caacgtgttg ctttccgtcg tgctcaaaaa
     7921 caagctattc aacgtacaat gcgtgctgga gctaagggaa tcaaaactca agtttcaggt
     7981 cgcttgaacg gtgcagatat cgcgcgtagc gaaggctact cagaaggaac tgttcctctt
     8041 cacacacttc gtgcagatat tgactatgct tgggaagaag cagatactac atacggtaaa
     8101 cttggtgtta aagtttggat ttatcgtggt gaagttcttc cagctcgcaa aaacactaaa
     8161 ggaggcaaat aacagatgtt agtacctaaa cgtgttaaac accgtcgtga gtttcgtgga
     8221 aaaatgcgcg gtgaagcaaa aggtggaaaa gaagtatcat tcggtgaata tggtcttcaa
     8281 gctactacta gctcatggat cactaaccgc caaatcgaag ctgctcgtat cgctatgact
     8341 cgttacatga agcgtggtgg taaagtttgg attaaaatct tccctcacaa atcttataca
     8401 gctaaagcta tcggggttcg tatgggttct ggtaagggtg cacctgaagg ttgggtagca
     8461 ccagttaagc gtggcaaggt tatgtttgag gttgctggtg tttctgaaga aatcgctcgt
     8521 gaagcacttc gtcttgctag ccacaagcta ccagttaaat gtaaattcgt aaaacgtgaa
     8581 gcagaataag gagaagacat gaaacttgaa gaaatcaaaa agtttgttgc tgagcttcgt
     8641 ggcttgtctc aagaagagct tgctaagaaa gaaaacgaac tcaaaaaaga acttttcgac
     8701 cttcgttttc aagctgcagc aggtcaacta gatcaaactg ctcgtttgaa cgaagttaaa
     8761 aaacaaattg cacgtgtaaa gactgtgcaa tctgaaatga aataatagat tgggaaagga
     8821 gtattctaaa taatggaacg taatcaacgt aaaacccttg ttggacgtgt tgtatctgac
     8881 aagatggaca aaacaatcac tgttatagtt gaaacaaagc gtaaccaccc agtctatggt
     8941 aaacgtatca actattctaa aaaatacaaa gcacatgacg aaaagaacct tgctaaagaa
     9001 ggcgatatcg ttcgtatcat ggaaactcgt ccactttcag ctacaaaacg cttccgtctt
     9061 gtagaaatcg tggaagaagc tgttattatc taatcaaact aaaaggagac aattgaaatg
     9121 attcaacaag aaactcgctt gaaagttgct gataatagcg gtgctcgtga gatcttgact
     9181 atcaaggttc ttggtggttc agggcgtaag tttgctaaca tcggtgacgt catcgttgca
     9241 tctgtaaaac aagctactcc tggtggagca gttaaaaagg gtgatgttgt taaggctgtt
     9301 attgttcgta caaagagtgg tgctcgtcgt ccagacggtt catacatcaa atttgatgac
     9361 aatgcggctg tcattattcg tgatgacaag actcctcgtg ggactcgtat ctttgggcct
     9421 gttgcacgtg aattgcgtga gggtggctac atgaagatcg tatcacttgc accagaagta
     9481 ctttaatttt aatcattaaa caaactaagt cccctaggct agcctagggt gcccataggg
     9541 gcgtaagaaa ataataggag aaacccataa tgtttgtaaa aaaaggcgac aaggttcgcg
     9601 ttattgctgg taaggacaaa ggtgttgaag ctgttgttct taaagcactt ccaaaagtaa
     9661 acaaagttat tgttgaaggc gtagccatca tcaaaaagca tcaaaaacca aacagcgaaa
     9721 atcctcaagg tgctatcgtt gaaaaagaag caccaatcca tgcatcaaac gttcaagttc
     9781 ttgataaaaa tggtgttgct ggacgcgttg gttacaagtt tgtagacggc aaaaaagttc
     9841 gttacaacaa aaaatcaggc gaagtgcttg attaatcacg aaggaaagga gaagcataat
     9901 ggcaaatcgt ttaaaagaaa aatatactaa cgaagtaatt cctgcgttga cagagaagtt
     9961 taattacaca tcagttatgg ctgtgccaaa ggttgagaaa atcgttctta acatgggtgt
    10021 gggtgacgct gtatcaaacg ctaaaaacct tgaaaaagct gctgcagaat tggcgcttat
    10081 ctcaggtcaa aaaccactta ttactaaagc taagaaatca atcgctggct tccgtcttcg
    10141 tgaaggtgtt gctatcggtg cgaaggtgac acttcgtggc gaacgcatgt acgaattcct
    10201 agacaagcta gttagcgttt cacttcctcg tgttcgtgac ttccatggtg ttccaacaaa
    10261 atcatttgat ggtcgtggta actacactct tggtgtgaaa gaacagctta tcttcccaga
    10321 aatcaacttt gatgatgttg ataaagtgcg tggtcttgat attgttatcg taacaactgc
    10381 taacactgac gaagaatcac gtgaattgct taaaggtctt ggaatgcctt ttgcaaaata
    10441 atagggggta actaaattgg ctaaaaaatc tatgattgct aaaaacaaac gtcctgcgaa
    10501 gtattctaca caagcttaca ctcgttgtga aaaatgtgga cgtccacatt ctgtttaccg
    10561 caagtttaag ctttgccgcg tttgcttccg cgagttggct tacaaaggcc aaatcccagg
    10621 tgttgttaaa gcgtcttggt aaaatgatga tgtgagagcg ttaagctacc taagcaaaaa
    10681 taggaaaatt gacgaagagt ctaaatactc taggaaattt tgcacctaaa ggtagtagct
    10741 tgaactcagt tcaaatgaac aaataatact atcagatatt atgtctgatt cgatgcaaag
    10801 gcaaagtgtc aatttgaaca cgggcgaaag ccggtgtcaa aaagataaac attccttgga
    10861 ggttttccct cctgcggaag tttcctattt tgactttggc ttttagcgcc ctttgtatca
    10921 tcgattaact agcaagtgca gcttgcaaac tactagtaag aggagaataa taaaatggtt
    10981 atgactgacc caattgcaga ctttttgaca cgtattcgta atgctaatca agtaaagcat
    11041 gaagtgttag aagtacctgc atcaaatatt aaaaaaggga ttgcagaaat ccttaagcgt
    11101 gaaggcttta tcaaaaacgt tgaagttatt gaagatggca aacaaggaat tattcgcgta
    11161 tttcttaagt acggtcaaaa tggtgaacgt gtcatcacta acttaaaacg tgtttcaaaa
    11221 ccaggtcttc gtatttattc taagcgtgag gatgttccaa aggttcttaa tggactagga
    11281 attgcaatta tttcaacttc agaaggtctt ttgactgata aagaagctcg tcaaaagaac
    11341 gttggtggag aagttatcgc atacgtttgg taatttaaga gacaaaagcc gtaacgaaca
    11401 atctaaaatt agaaaattat tgtggcttgc ttgcaaacaa aatagtttgt ctattttaga
    11461 tggcagttcg tcggctgtgc tcaaatgatg aacactatca acatagcaaa cgtaaaagaa
    11521 ctaattgaac atgggctaaa gtctgtgtga aaaagataaa tttttctaga aaccttggtt
    11581 tcatagtaat gtttcctatt ttcactttgc cttttacgcc ctaagtatct tagttcaccc
    11641 cgtgaaaact cgtcgcgtaa gcggcctgat aatttaacag gagaaaaaat taatatgtca
    11701 cgtattggta ataaggttat tattatccct gcaggcgttg aaatcattaa caacgacaat
    11761 gttgttactg taaaggggcc taaaggagag ctcactcgtg agtttaacaa aaatattgaa
    11821 atcaaagtcg aaggaaacga aatgactctt gtacgtcctg acgactcaaa agaaatgaaa
    11881 acaattcatg gtacaactcg tgcaaacttg aataacatgg ttgttggagt ttcagaaggt
    11941 ttcaaaaaag agcttgaaat gaagggtgtc ggatatcgtg cacagcttca aggctctaag
    12001 cttgttcttt cagtaggtaa atctcaccaa gatgaggtgg aagctccaga agggattaca
    12061 tttactgtag ctaatccaac atcaatttca gttgagggta tcaacaaaga agttgttggt
    12121 caaactgccg cttacattcg tagcctacgt tcaccagagc cttacaaagg taaaggtatt
    12181 cgttacgttg gtgagtatgt acgccttaaa gaaggtaaaa caggtaaata atgttcttag
    12241 tggaatatgg cataggcttg cttatgtcat gctctacaag ctcaattgat aatttgtcgg
    12301 aaagacaaac ttaaatatta agaggtgaaa attgtgattt cgaaaccaga taaaaacaaa
    12361 atccgccaaa aacgccatcg tcgcgttcgc ggtaaactct ctggaactgc tgatcgccca
    12421 cgtttgaacg tattccgttc taatacaggc atctacgctc aagttattga tgacgtagcg
    12481 ggtgtaacgc tcgcaagtgc atcaactctt gataaagaag tttctaaagg aacaaaaact
    12541 gaacaagctg ttgtagtcgg caaacttgtt gctgaacgtg cggtggctaa aggtatttct
    12601 gaagtggtgt ttgaccgcgg tggatatctc tatcatggac gtgttaaagc tttggctgat
    12661 gcagctcgtg aaaacggatt gaaattctaa tagggaggac acaaaataat ggcatttaaa
    12721 gataatgcag ttgaacttga agaacgcgtt gttgctatta accgcgttac aaaagttgtt
    12781 aaaggtggac gtcgtcttcg ttttgcagct cttgtagttg ttggtgatgg aaacggacat
    12841 gttggattcg gtactggtaa agctcaggaa gtaccagaag ctattcgcaa ggcagttgaa
    12901 gctgctaaaa agagcatgat tgaagtgcca atggttggca caacaattcc tcacgaggtt
    12961 tacactaact ttggtggagc taaagtattg ttgaagccag ctgtagaagg ttctggagtt
    13021 gctgctggtg gtgcggtacg tgccgtcatc gaattagcag gtattgctga tattacttca
    13081 aaatctcttg gttcaaacac tccaatcaac atcgttcgtg caactgttga aggattaaaa
    13141 cagcttaaac gtgcagaaga agttgccgca cttcgtggca tctcagtttc tgacttagct
    13201 taagaaaggg gatcatcatg gctcaaatta aaattacttt gactaagtct ccaatcggac
    13261 gtaagccaga acaacgtaaa acggttgttg cccttggact tggtaaatta aactcttcag
    13321 ttatcaagga agataatgct gctattcgtg gtatggtgac agcaatttct cacttggtga
    13381 cagttgaaga tgtcaaataa agagttagct agaaatctct gatttcttgc attagcatgc
    13441 agaaccggct tttgtgagtt attcctttga atgacaagca gtggtcggtt ggtgcatata
    13501 gcatcaggct atgacatagc ttgatcatgt ataggcgagt ttctatggag agtcctttcc
    13561 cttcatagag gcgctagcat tttacaaaaa aaggagaaaa aatgaaactt catgaattga
    13621 agcctgccaa aggctctcgt aaagtccgca atcgtgttgg acgcggtact tcatcaggca
    13681 atggtaaaac atctggacgc ggtcaaaaag gtcaaaaggc tcgtagtggt ggtggcgtac
    13741 gtctaggctt tgaaggtgga caaacaccct tgttccgtcg tattccaaag cgtggattta
    13801 caaatatcaa cactaaagag tatgctcttg ttaaccttga tcaattaaac gcttttgaag
    13861 atggcacaga agtaactcca gttgttctta aggaagctgg aatcgttcgt gctgaaaagt
    13921 caggcgttaa aattcttggt aacggcgaat tgactaaaaa attgactgtt aaagcagcga
    13981 aattttcaaa atctgctgaa gcagccatta ctgctaaggg tggttcaata gaagtcatct
    14041 aatgagggga tactcattat gttcttaaaa atactcaaag acgcattgaa gataaagaat
    14101 gttagaaata aaatattttt tacaatcttt attatcctta tattccgtat tggaacacat
    14161 atcactgttc ctggtgtaaa tgcaaaaagc ttagagcagc tgagtgagct tcccttccta
    14221 aatatgttga acttggtcag cggtaatgca atgagaaact tttcagtttt ctcaatgggt
    14281 gttagtccct atattacagc ctcaatcgtt gttcagctat tgcagatgga tattttgccg
    14341 aagtttgttg agtggggaaa acaaggtgag gttggccgtc gtaagctaaa ccaagcgacg
    14401 cgctatattt cccttgtctt agcctttgct caatctatcg gtattacagc gggttttaac
    14461 accttatcaa gtgtggccct agtcaaaaca ccagatgtaa gaacctattt actgattgga
    14521 gctttactga caacaggtag tgtgattgtg acctggcttg gtgaacagat taccgataaa
    14581 ggctttggta atggggtgtc tatgattatc tttgcaggta tcatttcctc tattccaaat
    14641 gctattgcaa ccattcgtga ggattatttt gtcaatgtga agtcaggtga cctacagtca
    14701 tcttatatcg ttgttggtat tctcattctt gcagtgcttg ctatcgtctt tttcacaacg
    14761 tatgttcagc aggcggaata taaaattcca atccaatata caaagcttgt tcagggtgcg
    14821 cctacaagct cataccttcc cttaaaagta aatccagctg gtgttattcc cgttatcttt
    14881 gccagctcga ttacaacaat tccaagtacg attatcccgt tctttcaaaa tggcagagat
    14941 attccatggt tgacaacttt gcaaggaatt tttaactatc aatctccaac aggaatgatt
    15001 gtttatgcct tgttaattat cctgttttca ttcttctata cctttgttca agtaaatcct
    15061 gagaaaacag ctgaaaatct acagaagaat tcgtcctata ttccaagtgt tagacctgga
    15121 cgagaaacag aagaatttat gtcatccttg ctaaagaaat tggcaactgt gggtgctatc
    15181 ttcctagcat ttatatctct tgttccaatt gcggcacaac aagctcttaa cctatcttct
    15241 agtattgcat taggtggaac tagcttgctg attttgattt cgacaggtat cgaaggtatg
    15301 aagcagcttg aaggttacct tctcaagaga aaatatgtcg gatttatgaa tattacagaa
    15361 tagaatatgg gttgacactg tcaaccttct attttgtttt taaatgacaa taagatttac
    15421 agagccttgg ttcctatctt cttattgcca tttgaaaaca aaaacaagga aaactaaatt
    15481 tcctattatc tttatgtcaa aagaggagaa aaagatgaat cttttaatca tgggcttacc
    15541 tggtgccggt aagggtacac aggctgcaaa gattgttgaa acctttgagc ttattcatat
    15601 ttcaacagga gatatgttcc gcgctgcaat ggctaatcag actgaaatgg gagttcttgc
    15661 gaaatcttat atcgataagg gtgatttggt gccagatgag gtaaccaatg gtatcgttaa
    15721 agaacgctta gcacaagctg atattaaaga aaagggattt cttttagatg gctatcctcg
    15781 taccattgag caggcacatg ccttagatga aaccttaaaa gcattgggac ttacgttaga
    15841 tggtgtgatc aacattgagg ttgaccctgc gtcactcatt gacaggctta gcggtcgtat
    15901 catcaacaaa aaaacagggg aaaccttcca taagatcttt aacccaccag tgggagacta
    15961 taaggaagag gacttttatc aacgtgaaga tgataagcct gaaacagtta agcgtcgctt
    16021 agatgttaat attgcacaag gtgagcctat tatcaagcat tatcgtcaag caggcattgt
    16081 tcgtgacatt gacggaaaca aggacatttc tgaggtcttt gctgacataa aaaaggtcat
    16141 cgaaaacctg aaataaattc cagaaaatcg cttgcgaaag tgattttatc gtgatatact
    16201 agactagtct gacttataat tgttacctct gtgctcagag gacatcaaat cgaaatttag
    16261 ggggtacttt tgcgtggcaa aagaagacgt gattgaaatt gaaggtaaag ttgtcgaaac
    16321 tatgccaaat gcaatgttta ctgttgaatt ggaaaatgga catcagattt tagcaaccgt
    16381 atcaggaaag atccgcaaaa attacattcg tattttagtg ggtgatcgtg ttactgtaga
    16441 gatgagtcct tacgacttga cacgtggacg tatcacatac cgctttaaat agtcgaaata
    16501 attggaggga ttaaaacatg aaggtaagac catcggttaa accaatttgc gaatactgca
    16561 aggttattcg tcgtaacggt cgtgttatgg taatttgtcc gacaaatcca aaacacaagc
    16621 aacgtcaagg ataagataga aaggagaaaa aatggctcgt attgctggag ttgatattcc
    16681 aaatgataag cgtgtagtaa tttcacttac ctatgtgtat ggaattggtc ttgcaacatc
    16741 taaaaaaatc ttagcagcag caggtgtctc tgaggacatt cgtgttaaag atttgacatc
    16801 agatcaagaa gacgctatcc gtcgcgaagt ggatacaatt aaagttgaag gtgatcttcg
    16861 tcgtgaagta aacctaaata tcaagcgttt gatggaaatc ggttcatatc gtggaattcg
    16921 tcaccgtcgt ggacttcctg tacgtggaca aaacacaaaa aacaatgctc gtactcgtaa
    16981 aggtaaagct gttgcgattg caggtaagaa aaaataaaat aggaggtaaa aaaattggct
    17041 aaaccaacac gtaagcgtcg tgtgaaaaag aacatcgaat ctggtgttgc acatattcac
    17101 gctacattta ataacactat tgttatgatt acagatgtgc acggtaatgc tttagcatgg
    17161 tcatcagccg gtgctcttgg ttttaagggt tctcgtaagt caactccttt tgctgctcaa
    17221 atggctgcag aggctgctgc gaaatctgca caagaacatg gtttaaaaac tgttgaagtt
    17281 actgtaaaag gtcctggttc aggtcgtgaa tcagctattc gtgccctagc tgctgccggt
    17341 cttgaagtaa ctgccattcg tgatgtgact cctgtaccgc ataatggtgc tcgtcctcca
    17401 aaacgtcgtc gtgtataatc acagtaacaa atagtacaca agtttcgttt cgaggggtga
    17461 aagaatgatt gagtttgaaa aaccaataat aacaaaaatt gatgaaaata aagattacgg
    17521 tagatttgta atcgaaccac ttgaacgtgg atatggtaca actctaggta attcacttcg
    17581 tcgtgtactc ttgtcttcac ttccaggtgc agctgttaca tcaatcagaa ttgatggagt
    17641 actacacgaa tttgatacaa tcccaggtgt acgtgaagat gtcatgcaaa ttatccttaa
    17701 tgttaaggga cttgctgtga aatcatacgt cgaagacgaa aagattatcg agcttgatgt
    17761 agaaggtcca gcagaggtaa cagctggaga tattctcaca gatagcgata tcgaacttgt
    17821 taaccctgat cattatcttt ttactattgc tgatggttat acattgaagg cttcaatgac
    17881 tgtcgctaaa aaacgcggct atgtaccagc agagggtaat aaaaaagatg atgcacctgt
    17941 ggggacgttg gcagtagatt caatctatac gccagtaaaa aaggttaatt atcaagttga
    18001 gcctgctcgt gtaggtagta atgacggctt tgataaattg actattgaaa tcatgacaaa
    18061 cggaacaatt attcccgaag atgccttagg tttatctgct cgagttttaa tcgaacactt
    18121 gaatttattt actgatttaa cagatgttgc aaaggcaact gaagtgatga aggaagctga
    18181 aaaagtgaac gatgaaaagg tacttgatcg cactattgag gaacttgatt tgtccgtacg
    18241 ctcatataac tgcttgaaac gtgccggtat taatactgtc ttcgatttaa cagaaaaatc
    18301 tgagcctgaa atgatgaagg tccgtaacct tggacgtaag agtcttgagg aagtaaaggt
    18361 caagcttgct gacttaggtt tgggactaaa aaacgataaa taacatagga ggataaaatg
    18421 gcttaccgta aactaggacg cactagctca caacgtaaag caatgcttcg tgacttaacg
    18481 acagatcttt tgattaacga atcaattgta acgacagaag cacgtgcaaa ggaaatccgt
    18541 aaaacagttg aaaaaatgat tactcttggt aaacgtggtg atcttcatgc tcgtcgccaa
    18601 gcagctgcat acgttcgtaa cgaaatcgca tcagaaaact atgatgaagc tactgataaa
    18661 tacacatcaa caacagctct tcaaaaactt ttctctgaaa ttgcgcctcg ttatgcagaa
    18721 cgcaacggtg gatacactcg tatccttaaa acagaaccac gccgcggaga tgctgctcca
    18781 atggcgatta ttgaattagt ttaattttta tcaattttgt tgagtgttat gatgatggag
    18841 cagttccttt aagctgttct tagtctagct ctggtctacc gctaggacct ttcctagcgg
    18901 taacactcac catgttgaga ataagtaacg cttgtttacg aaaggtctct aagctgtagg
    18961 tgcccttcgt aagcaggcgt tttgttgtga ctccatgtta actgtagtag atgactaata
    19021 tctaatatct agagaggatc agcttggtgc tctcttttct gatattaaaa gcattgggaa
    19081 tcttggtttt gaagttctta aagctcctaa agccaaagtc tttcgcttga tgtctttggt
    19141 catcttgtta gtggtctccg gcttagcatt ggaataaggt agttcaaagc attggtgatg
    19201 taagatctat acttcctgaa ggtcttgaaa accgttttga aggtgtgatt gacctgtagc
    19261 gggagtagat tagatcaatg gcgtttggct gctttgaaaa tttaggtgac aattgttttt
    19321 gtatctttgt ttaaaaatgg tataatatta aaacattaaa caaaatgtac ataaaaaagc
    19381 catataaaag aatgatatta agataatgtg atcaatagtt ttagaaaatg aatgtgtaag
    19441 gttaaggtat gcccccttga tataatgcta gttttacgaa gaggcattct gtacagacat
    19501 aatgcactct tacaaatgat acggtaattg ctcaacaagg cgcaacagcc ttggcaaatg
    19561 taatatttgc cttagctagc agcgaattag ttacgcttga tacatagaca agggtttctg
    19621 gcatacagca gcagatggtg tgcctgtctc agagagtggc tgcttggctt atcctattca
    19681 tgttttaaaa cttacaggag gtgttatgtg gcctttggtc gatggatatt tagctaggtg
    19741 aacagctatt agctgtaaat atgaggtagg agctttagtt tgcatgatgt taaatgaatt
    19801 gaaacagact taggaaagct tggcttagca actatcacgc aagttcttaa caacgataaa
    19861 gatcgtatgg gaaaatatga tcaagcatca acggacatga gatgtgtttt atgaagaaac
    19921 cattatactt ttataagact tatttagttg tttttctttg cggacttgtt tgaggagtag
    19981 tctacatagg caataggctc aggcttacag cacttaggag acattagagc atgagaagca
    20041 ctaactggct agtgatagaa aagtaatagc acagtgtttt tataactaac aagaggagta
    20101 gacattctat gagtattgac atgtatttga gcttatctga agagcaggca cagagtgtag
    20161 aggctgtctt agctaggcga caaacagcct atcaatcctt acaggagacc ttgatccaat
    20221 tgatttctaa cagtcctgat ttatcagggc ggacctatga ttctgctaag gcttatagta
    20281 gtcaagtgct aattcctttg ttaaaggggt gtatgctttt agatgaggcg attataacag
    20341 cctgtaagag gctacctagt gagtaccgta gtcaggtaga ccaaattgat ttgaaggaga
    20401 gtgatctggt tgagcgtatt gcccagttcg atcatgtgat tggtcggtac atggatttga
    20461 ttagtattga atacagtaga gaggagccta gctattctta tatctctcat ttaagatcag
    20521 ctgagcagct ccatcgggcc gttaagcggc gtcttgagga gatattgcga aggctaaggc
    20581 attttgatac caactcagtt cacctttttt cgactattca gactttggca gcagcggtac
    20641 aaataggcat gcgtcaagct aggacctcgt ggcatgcagg aagtcaggta tttgtgattt
    20701 cagaggatat ggcatgggcc gatacgatta attctaagtg gtcaaaaagt aaagggttaa
    20761 gctatcttag tgattatgtt tacgacccag atgtgctctc taagagagca gctattaatc
    20821 actcttggat taaaacaggc tatactatgt ctaaaaattt tggcaaagct gtttcaaaag
    20881 attatacaaa agcaagcttt ttgagctatg gtaaggcagc caaggcgact ggctggactt
    20941 ctatggcagt agatactgga ataactagtg taagggaata caataagaaa aatagtagag
    21001 cctatggcag tgagggcaag gcgcttattc atgctagtgt ggctcaaatc aagagcatgg
    21061 gacctataga aggggcgata attggcagta aagctggacc ttggggagca ttaatggggt
    21121 ttgttacagg aggcattaat gttacttggg gagtagtgca tccagagtct aaggacaaca
    21181 tgtttttatg gatacaagat aaaatggatg atgtttacga ttcgattgtt cagacagatc
    21241 ttggcaaagg gacgcaccat gctaaagaaa gtgtcaaagg tcatatcggt cgagctattg
    21301 taaggacatg ggactttgtc agtcaatcat ttggtaaagg agtgggctat gacatttaaa
    21361 gatcagcttt ttagtgggac gtttgagcaa tcaaaaaaga ttgtgtctaa aagtatattg
    21421 acagaagaag gtgcgcagat tggagtattc tcatctatga gtctatggaa gagaataaca
    21481 ggcttgatga tgttgccatt atttgctatt tcatatggag taggagttgt gttacctgaa
    21541 cactttcaat aatcaacaga aggagttcaa gctatttcat tggctgcaat agagattatt
    21601 gccagattag gacagttcag tcgatacttt atcatttgtt ttatttgtat gtctgttgga
    21661 ttaattatta gtaatatcct tccaaagcct aactaggctt atcaattatt atatggcaat
    21721 gctactctta ttatacttag tattacaact attatctcag ccttcccttt aactgctggc
    21781 cttacaattg cagcttttgg ctggatcggt tttttgcttc agctattgct ttgcctttat
    21841 ttgtggaagg tttgtgtcat agataagtgt caacagctac gcacagcaat ttatcaagaa
    21901 agcaccatag cacctgattg gggcagtaag ctagtaagct ttattaagtc ttatggtggt
    21961 atcttattag gcctctctgt tctcaaccgc tggactctca atctaggaga gctagtcaag
    22021 gaaagccctg gtttgttgag ttttctgtac ggctggattt ttctattgtt catgtttttg
    22081 atgctatttg cactgggtca agcgttaaaa aataccatca tagcctatta tttttttaga
    22141 tatcaaaaag aataccgcaa gcattttaat ataagcgatg agcagtggta cggtaaatgg
    22201 cgtttaaaaa tattattaaa ataaacgata taaggagtaa tcatatgcaa aaagaattat
    22261 taccgttagg aagtgttgtc tatctagagg gagcaacaag caagctaatg attgtcggac
    22321 gtggtcctat atttgaatct aatggccaaa atgtctacag tgattatgtt ggagtaatgt
    22381 atccagaagg gatcaatcca gaagacgcga tttttttcaa ccatgaagat attgcaaaaa
    22441 cagtctttga aggcttcaag gacgaagaag aacaacgctt tttagaagtg tattctgatt
    22501 gggagagtac tttagaaatt tccaaaataa agctatagat gaactgtagc agatatattt
    22561 gtcagtagat tgtcatgatt atattgaaag attatgactt tctctggctt aaatacctct
    22621 aaagttccaa agtttagaaa aggctttaaa atgagtgtta taatagcatt tatgctcatt
    22681 aaataaaggt agcatttcaa tagaatcggt aaaaaaa
//
LOCUS       DARYLJ010000037        20462 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYLJ010000037 DARYLJ010000000
VERSION     DARYLJ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20462
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(85..1350)
                     /locus_tag="TU746_001399"
     CDS             complement(85..1350)
                     /locus_tag="TU746_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL0891738.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TU746_001400"
     CDS             complement(1364..2221)
                     /locus_tag="TU746_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891739.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TU746_001401"
     CDS             2564..3856
                     /locus_tag="TU746_001401"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL0891740.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TU746_001402"
     CDS             complement(3971..4744)
                     /locus_tag="TU746_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL0891741.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TU746_001403"
     CDS             4869..5615
                     /locus_tag="TU746_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0891742.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TU746_001404"
     CDS             5630..6610
                     /locus_tag="TU746_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL0891743.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TU746_001405"
     CDS             6849..7169
                     /locus_tag="TU746_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0891744.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TU746_001406"
     CDS             7194..7502
                     /locus_tag="TU746_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0891745.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TU746_001407"
     CDS             7513..8817
                     /locus_tag="TU746_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0891746.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TU746_001408"
     CDS             9098..11515
                     /locus_tag="TU746_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL0891747.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TU746_001409"
     CDS             11530..12198
                     /locus_tag="TU746_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL0891748.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TU746_001410"
     CDS             12323..13414
                     /locus_tag="TU746_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL0891749.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TU746_001411"
     CDS             13921..14973
                     /locus_tag="TU746_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL0891750.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TU746_001412"
     CDS             15002..15580
                     /locus_tag="TU746_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0891751.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15778..16686
                     /locus_tag="TU746_001413"
     CDS             15778..16686
                     /locus_tag="TU746_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0891752.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16922..18268)
                     /locus_tag="TU746_001414"
     CDS             complement(16922..18268)
                     /locus_tag="TU746_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0891753.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(19308..19412)
                     /locus_tag="TU746_001415"
     CDS             complement(19308..19412)
                     /locus_tag="TU746_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0891754.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
     gene            complement(19792..20307)
                     /locus_tag="TU746_001416"
     CDS             complement(19792..20307)
                     /locus_tag="TU746_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEL0891755.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFNCFYRAFKRYLK
                     YRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNNLNNYKAVIKQYPHKTIVLKNQKQL
                     NHYMNSIQHDS"
BASE COUNT         5793 a         4111 c         4564 g         5994 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag taaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggcaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aacaaaacct cggagacaaa ctagccagca gctatttctc atgagtaatc aacatgttaa
    15721 aatcttcttt ggagatatta gacaaccata attattatat catcaaagga gagaaagatg
    15781 acaaacaaaa caaagcgtac aggattggta cgcaagtacg gtgcctgctc agcagctatc
    15841 gccttagcag ctcttgcaag cctgggagca ggtaaagcag taaaggcaga ccagccagca
    15901 gcactaaaat atccagaacc tagagactat tttcttcata ctcgtgaagg tgatgttatt
    15961 tatgatgagg atataaaaag atattttgag gatttagaag cctatttaac agctagactt
    16021 ggtgggattg ataaaaaagt agaagaagct gcccaaaagc caggtattcc aggtcctact
    16081 ggccctcaag gtcctaaggg agacaaagga gatccaggtg cccctggtga gcgcggtcca
    16141 gctggaccaa agggcgatac gggcgaagcc ggaccaagag gtgagcaagg cccagccgga
    16201 caagctggag aacgtggacc aaaaggagat ccaggtgctc caggtcctaa aggtgaaaag
    16261 ggtgatactg gtgcagttgg tcctaaaggt gaaaaaggtg ataccggagc aaccggacca
    16321 aagggagaca agggcgaacg cggtgaaaaa ggcgagcaag gccaacgtgg cgaaaaaggc
    16381 gagcaaggcc aacgcggtga aaaaggcgag caaaaaccaa agggtgatca aggaaaagat
    16441 acaaaaccat cagctccaaa agcacctgaa aaggctcctg caccaaaagc tccaaaggct
    16501 tcagagcagt catctaatcc taaagcacca gctcctaagt cagcaccaag caaatcagcg
    16561 gcaccaacag gtcaaaaagc agccctacca gcaacagggg aaatcaacca cccattcttc
    16621 acccttgcag ctcttagtgt catcgctagc gtaggcgtcc taactctaaa aggaaaaaaa
    16681 gactaagcta gttattgtat ctttcctgta tgacactagc taacagctaa tcacaaacac
    16741 cagagagagg tcttttctga cctctctttt atatacactg agcacatgct tacctcaaaa
    16801 agacagtagt ctaagtttga ctactgtctc aaaaatcatt tttatctaaa gctttgatca
    16861 gcttgacaaa tggtagagaa ggacttgatt tctaaggcct ttgacctcag tttgactttt
    16921 gttaattttc cttacgtttt atagctgcta caccagctgt agccataact gcaagtgcag
    16981 ctgcggtgaa gaatgggttc acagcctcac ctgttgctgg caattgatta gtcgttttct
    17041 tcatctcagc tttagctgct gctgctttag aagctgtgtg agctggcgct gctactttac
    17101 ctgcttgatc agctttttca ggactgagtg gtttagcctc tggcttagtt tctggtttgg
    17161 tttctggaac tttaggtgcg tcttcttgtg gttttgaatg tggacttgat tttttaatat
    17221 ctttagcatc tagggcaacg cttctttcct cacctgttgt agcttgagaa agctttttgc
    17281 cgttgacaaa aatctcatag aaagtgccat ctagaagccc tttagaaaat acagctttgc
    17341 catcagctcc tgttgttact ttctctatca cacgacctac tctatgcttt agagtgactt
    17401 cttgtcctga taaaggttca gcatcttcat tacgaacgat aacaaccaaa ggtgttttac
    17461 tgtattctgg ctcaactgtt ccttttccgt caacagtaaa gctagctgaa tgcttgtcgc
    17521 catcaacacc tgttcgtaca gtatagcctt gaggaacgcc attcacaaaa attgataaac
    17581 ttcttcctaa aggaagcttg tcaaaaacag cttgtccttt ttcatctgtt gtcacagtcg
    17641 caagtgtttt tctgccactt gttatatcta ccacttggac gtcttttcca gataatactt
    17701 taccctcagg gtctataact gttgcggtaa aagcaaagct accttcaata acatcatcat
    17761 gatggtggtg tgcatgatca ctgtgatgac tactctgccc atcgtcaaaa ggcttagaaa
    17821 catcaatctt atccaataaa ataacatgat gatgatcgtc atgtggatac atcaaggcct
    17881 taccctctga agtatccaat aattgaatct tgtctaatgg caagcctgta tttttggcga
    17941 tataagcttt ttttacggca ataatatctt cagctgattg attagtgtct agcggtaatt
    18001 tatcagctgc tgctacagga tttgcggttt ctgatgcttt tgtaattggt ttatcagcca
    18061 tcacctcagt gctgtcagat aactgttgat tagctgtatc tgcagtatct ttatcctcac
    18121 ctaacctcgg ttggactaca gtgtgattat ccactgctgg tgattcatca gcaaatgcta
    18181 ctgacgagtt agttgacatc gctaaaccag cagccattaa agcagctggg ataagtaaag
    18241 agtatcgggt aacttgattc tttttcatta ataactcctt ataactatta ttcattttaa
    18301 ttaattaacc agttaactat atcaatctat caaaaaaaat atagtatgtc aacctcttaa
    18361 agtgatttaa tcagaacaaa cgtatgaaga aaatcatttg gtgaaaaaga agcttatttt
    18421 agctgaaata gatccattat aaaagaggtg tcgtgaagta actcaatatt cacctatttt
    18481 tgtcgcaagt attctaatag gaatagaaaa agggcagttg cttgcaacaa ctacccaatg
    18541 taaaaccgtt aaagacggtg acagaaaata actgttaact gaactacctc aaaagttaaa
    18601 ccaaagatct aaccgttgga tgttggtttg tagagcggtt atttttttat tgttatgttt
    18661 acaacgacta agctcatcag tgtaagggaa agggacttcc atattaagaa gtatatatac
    18721 atcctagatg agacgtgtaa tgaatgggtt gaacaaatag ttgcttaatt ttgggataag
    18781 ggttataata aaaatagaaa aagggcagtt gcttgcaaca actacccaat gcagaaccgt
    18841 ttgagacggt ggctggtttt atagttaaaa gataaccgtt aactcgccaa agttaaggac
    18901 ggttattttt tattgtcatc tttgaagatt tgatagcaca agctgataag cgcaatagta
    18961 aagctactaa agcctaaaag gatttatacc acttcaaaag ctgtcaatgc tttgactcat
    19021 cctttctgtt agattttgat gaactgccca taggcctcac ctacctttca gaaataagag
    19081 ccaccgtctt aacctttctg ctttatcatt atagcatatt gttattaagg ttgactattc
    19141 agactcgtct aaagaagtgt aatagttgct taattttggg ataagggtta taatgaaaat
    19201 agaaaaaggt agttgctcga cacaactacc catgcagaac cgtttaagac ggtggcatgt
    19261 tttatgttat taaaaaataa ccgttaactc gccaaagtta aagacggtta ttttttattg
    19321 tcatctttga agatttgata gcacaagctg ataagcgcaa tagtaaagct actaaagcct
    19381 aaaaggattt gtaccacttc aaaagctgtc aatgctttgg ctcctccttt ctgttagatt
    19441 gtgatgaact gcccataggc ctcacctacc tttcagaaat aagagccacc gtcttaactt
    19501 ttctgccttt ttattatagc ataccctatc tctgattgac tagcttaaga aggaggggat
    19561 gtgatttgga tacaaatttt tgttaacttt tttaaagtct ccaaatgatt taaaaaaatg
    19621 atattaatgc tctaagtaag aatattaata atatggtttt accacttatt gtatgaggta
    19681 tcatttctaa agagttattt ttcagacaga aggcttgtta aagcaaacag aagcaatact
    19741 aaaggcatta gatgataatc aaggcctttt tcatgtctta aaatgagtat actagctgtc
    19801 gtgttggata gaattcatat aatgatttaa ctgcttttga ttttttaaaa cgattgtttt
    19861 atgaggatat tgtttaataa ctgctttata gttatttaaa ttattttttg agcgtccgtc
    19921 taacagaatc catttcataa attcaacatc aaatttttca ttacagtttt cagccatatc
    19981 aggacgtgtt tgtcccctat attttaaata tcgcttaaaa gctcggtaaa aacaattaaa
    20041 tctattaaag ttaaaatata taatgtgatc agcctctctc atacgctctt cataaagaca
    20101 gcttgaataa ttaccttcaa taatccaatg tttttgtgac ataaatgttg atatatcaga
    20161 gaccatttga ctaactgttc gctcttgcca gtttgatgca aaatgaattt tgtctaaatg
    20221 aagtacagca caattgtagt gttgacctaa aacatttgct aaagtcgact ttccagaacc
    20281 actatagcca attattacaa ttttcaatct ttgtctcctt tgtcaatgct gtactttgac
    20341 ttatattata gcataaagaa tatattttgg ggacaaatcc tctttagaca agcaaaaaag
    20401 cctttcccga ctttatcact tgttttagtc cacaccttac tcaacccctt ggtagagtaa
    20461 gg
//
LOCUS       DARYLJ010000038        19724 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYLJ010000038 DARYLJ010000000
VERSION     DARYLJ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19724
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(229..699)
                     /locus_tag="TU746_001417"
                     /pseudo
     CDS             complement(229..699)
                     /locus_tag="TU746_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            914..1135
                     /locus_tag="TU746_001418"
     CDS             914..1135
                     /locus_tag="TU746_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL0891756.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1165..1458
                     /locus_tag="TU746_001419"
     CDS             1165..1458
                     /locus_tag="TU746_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0891757.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            2595..4427
                     /gene="lepA"
                     /locus_tag="TU746_001420"
     CDS             2595..4427
                     /gene="lepA"
                     /locus_tag="TU746_001420"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL0891758.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            4969..5406
                     /gene="msrB"
                     /locus_tag="TU746_001421"
     CDS             4969..5406
                     /gene="msrB"
                     /locus_tag="TU746_001421"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL0891759.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            5694..6713
                     /locus_tag="TU746_001422"
     CDS             5694..6713
                     /locus_tag="TU746_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL0891760.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            7057..7482
                     /locus_tag="TU746_001423"
     CDS             7057..7482
                     /locus_tag="TU746_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL0891761.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            7497..7988
                     /locus_tag="TU746_001424"
     CDS             7497..7988
                     /locus_tag="TU746_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0891762.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            8006..8815
                     /locus_tag="TU746_001425"
     CDS             8006..8815
                     /locus_tag="TU746_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0891763.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            8812..9639
                     /locus_tag="TU746_001426"
     CDS             8812..9639
                     /locus_tag="TU746_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0891764.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGVVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            9829..11463
                     /locus_tag="TU746_001427"
     CDS             9829..11463
                     /locus_tag="TU746_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0891765.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            11467..12252
                     /locus_tag="TU746_001428"
     CDS             11467..12252
                     /locus_tag="TU746_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0891766.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            12276..13286
                     /locus_tag="TU746_001429"
     CDS             12276..13286
                     /locus_tag="TU746_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0891767.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            13539..15323
                     /gene="uvrC"
                     /locus_tag="TU746_001430"
     CDS             13539..15323
                     /gene="uvrC"
                     /locus_tag="TU746_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL0891768.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            15451..16053
                     /locus_tag="TU746_001431"
     CDS             15451..16053
                     /locus_tag="TU746_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL0891769.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            16134..17543
                     /gene="pepV"
                     /locus_tag="TU746_001432"
     CDS             16134..17543
                     /gene="pepV"
                     /locus_tag="TU746_001432"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL0891770.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHIPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(17810..19186)
                     /gene="mnmE"
                     /locus_tag="TU746_001433"
     CDS             complement(17810..19186)
                     /gene="mnmE"
                     /locus_tag="TU746_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL0891771.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVSIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            19458..19679
                     /locus_tag="TU746_001434"
                     /pseudo
     CDS             19458..19679
                     /locus_tag="TU746_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
BASE COUNT         5619 a         3637 c         4490 g         5978 t
ORIGIN      
        1 ggttgagtaa ggtgtggact aaaacaagtg ataaagtcgg gaatgacttt tgtaggcata
       61 atttcacctc gtgacgatac cgttacttct ttttgaccaa gaaaagaaaa tgaaagtaaa
      121 aatatgacga ataatgttaa tggtataata agaattatcg caaaattatg atagcgtcgc
      181 tgataaaatt cagcacttct aaacagattt ggattcatga atatctcctt acttactaaa
      241 taaatgatga tagaagcctt gatgcgtcat taattcgtta tgcgaaccta tctcgattat
      301 ttttccttta tcaagtacaa caatttggct agtacgttca gcagtactaa gacgatgggc
      361 aacgaaaata atcgttttct cggtcattga cattaggtta tcaatcactt ttttctccgt
      421 taagacatct agtccgcttg tcgcctcatc gagaattaga ataggagact tggttaataa
      481 tgctctagct aatgcaattc tctgtttttg tccaccagaa aatcctgccc catcagatag
      541 ttctgtctga tagcccatag gcatttgttc aatatcttct ctaatttctg ccatatcaca
      601 ggcattgata atatcctctt gagtaatcgc ttggtttgca ccgagagtaa gattttctaa
      661 aattgatcca ctaaaaatat aagcttgttg aggcagatat tggttatcga aacgtcctaa
      721 atggtaatct gacaaatcta tcaaattatc tcaaacggtt gaatttaagt cttaagcggt
      781 aaatttttcc catttaggac gtttcgatga ctgtttagga aatggagaac aaattttaac
      841 cgaaagtgtt atactaagtc tgtcaagctt gcaaccggac aaaataaaaa cacatataaa
      901 ggaggtattc gtcatggata caaaatttac agcgttgact gaagagcaat tgaaatcagt
      961 tgagggtgga aaaaatggag ttgtaaaatt acctggaggg accggtgtat attgttggaa
     1021 tacaggaaaa aatagtgcaa aatgtggtat ggactggagt gtggcaggac catatgttgg
     1081 taagataatt gtcaatggtt gggttaacca tggaccttgg gcaagtcgtc cataatttta
     1141 atttatatag agaggtgtga aatcatgaat gaaagagatt tagtacagct gatagaacag
     1201 actctaaaag atgaagaggt gcaaaataat gtcacttata ggaatctttt ggaagaaagt
     1261 ctccagcaat tatcactcaa aaagcctgtg tatttagtta gtaccaggtt agcaggacat
     1321 atttcaacct atctaatgac aaatcattat gaggcaccaa aagcgattat agttcttgct
     1381 caatctatcg catcaacccc agctaaacat agaggtttaa tttctatacc attctggtta
     1441 agtaatatat ttcgttaaaa aatattttca gatcaggatt tagaaggagt tgtagattgg
     1501 caatgcactc ataaaataag acacattttt tggagttttt tgcttgaact cctaactttt
     1561 acattagtct ataaacagtc aaaggaagtt ctttcaatct ctcaaattgc aaaacaattt
     1621 tggctatatt ttaaaagtac aattttgatt ccaattttag ttacaatcat tcttataaag
     1681 gagattttgt caagtacatt acaaataatg atttattttt accttaatgt tgttgtcatg
     1741 tgctacgcta ttggaatgat cttatcgtta ggttatgtga tttcacccaa gcactctata
     1801 ttcaataaaa ttaaaaatat aaaattaaat aatagagtat cccaagagat tgccgaatcc
     1861 caatttacca gtcttttaga gcgaagagcg acttgaagaa actgataaat ttatttggtt
     1921 ttctgctaaa aatcctgcca aaaaatcttt ggcaggattt ttattttact aagagatatt
     1981 taggagtggc tttgtcattt aatgcagatt atgatatagc aggagacata ttgttgaagc
     2041 tgtctatgtc acttttggtg gcaggtaggt cttattggaa ttggtgactt atgacattta
     2101 tcggtggctg taagcgtttg actttttcac gtttcatagt ggtccgctct ggaatgagtg
     2161 ggtatttttt cagaatatga tcaaagatag atgacatgtt ttacagcagg ctatagctgg
     2221 tatgatttgt ttaaaaaatc aaggccaatg ataagtgctg ggtgacataa gtcttatggc
     2281 tttacttctt gttagcttgt gtcagcaggt gctgagtcaa tcgttgtagg aattatcgta
     2341 aacctaacag tagctgctgt tctatttgtt tattttctgg tttctattca aatttctaaa
     2401 atgctagggt aacaaatatg aaacaagcaa gtggcgtact gcgaacagct tgataactta
     2461 ttgcctgctt aaagagggtg ctgttatgct tggttttatt aggcttatgg catgggatta
     2521 aaaggttgct gtagcgccat tgtcattatt ttggtacaat aataggtaaa agactaaatg
     2581 tataggaaaa tagaatgaac agtcaagaat taaaaaaacg tcaggagaac attcgtaatt
     2641 tctctattat tgcccacatt gatcatggta agtcgactct tgctgaccgg attttggaaa
     2701 agacagaaac ggtttcaagt cgtgaaatgc aggcacagct ccttgattca atggacttgg
     2761 agcgggagcg tgggattacc atcaagctaa atgcgattga gctgaattat aaggctaaga
     2821 atggtcaaga ttatattttt cacttgattg atacaccagg gcatgtggac tttacctatg
     2881 aggtgtcccg gtcactagct gcctgtgagg gtgctgtttt agtggtggat gctgctcagg
     2941 ggattgaggc acagacccta gcaaatgtct atctggcgct tgataatgat ttggaaattc
     3001 ttccagtgat caacaagatc gatttgccag cagctgatcc tgagcgggtt cgtcaggaaa
     3061 ttgaggacgt gattggtcta gatgcttcgg aggctgtact tgcctctgca aagtctggga
     3121 ttggtattga agatatttta gagcaaattg ttgaaaaggt tcccgcaccg tctggtgatg
     3181 ttgatcaacc gctgcaggcc ttgatttttg attcggttta tgatgcttat cgtggggtta
     3241 tcctgcaggt gcgtgttgtc aatggtatgg tcaagccagg tgatacgatc caaatgatgt
     3301 caaatggaaa aacctttgat gtgactgagg tggggatttt tacccctaag gctattggta
     3361 gggattttct tgctactggt gatgttggct atattgcggc ctcaatcaag acagttgctg
     3421 atacgcgtgt cggtgatacg gtcactctgg ctacaaatcc tgcagcagag cccttgcatg
     3481 gctacaagca gatgaatcca atggtgtttg cagggattta cccgattgag tctaacaaat
     3541 acaatgatct tcgtgaggcc ttagaaaagc ttcagcttaa tgacgctagc ttacagtttg
     3601 agcctgaaac ctcgcaagca ttgggctttg gttttcgttg tggctttctt gggctgttgc
     3661 acatggatgt cattcaagag cgtttggagc gtgaattcaa cattgatttg atcatgacag
     3721 ctccgtctgt tgtctatcat gttaatataa ctgatggtga catgcttgag gtctctaacc
     3781 cgtcagaatt tcctgatcca actaaggtag atagtattga ggagccttat gtcaaagccc
     3841 agatcatggt gccgcaggag tttgttggtg ctgttatgga gttggcccag cgtaagcgtg
     3901 gagattttgt gacgatggat tatattgatg acaatcgtgt caatgtgatt taccatattc
     3961 ccttagctga aattgtgttt gacttctttg ataagctgaa atcatcaacg cgaggctatg
     4021 ctagctttga ctatgaaatt gctgaatacc gtcgctcgca gctggtgaaa atggatattt
     4081 tgttgaatgg tgataaggtt gacgctctta gctttattgt tcatagagca tttgcctatg
     4141 agcgcggtaa gctgattgtt gagaaattaa agaaaattat tcctcgtcag caatttgagg
     4201 tgccgattca agcggctatt ggtcaaaaga ttgtggctcg ctctgatatc aaggccttac
     4261 gcaaaaacgt tcttgctaaa tgctatggtg gcgatgtttc ccgtaagcgt aagttgcttg
     4321 aaaagcaaaa ggctggtaag aagcgtatga aggctattgg ctctgttgag gtgccgcagg
     4381 aggccttctt gagcgtccta tcaatggacg atgagagtaa gaaatagtga catgttaagt
     4441 aaggagctgg atcatgcgat ctggctctta tgcttgatgt ctcgataggc tagaaaatag
     4501 ggcttgtgtc atgataggct tgtatgtttg agatggtttg gaacataatg actctatcat
     4561 atctgtagtg gattgacaaa gagccgtaaa ccattgatat ttggatagtt aatttcgagt
     4621 tattctgtag tactctctta aggtctttca tatgagcttt tctaatgttg gtttggttgc
     4681 ttttcatgat aagtcatatg ggattttttt ggtatactga aaaaagccta tagcctctac
     4741 agtggcgtct ccctctacag agatgataga gccagagtga ttgttacgat ctggagatgt
     4801 ggcgctaggc attaatgcag gaggacttaa ccagattgct gttaggcttg aaatcttaag
     4861 ctatattgat tgtcagcttg atttagagaa gtctaagttt atggctcaca aatgctcggt
     4921 ctttttgtta caatagagtt aatcagttat ttttataagg agacagctat ggaatctaag
     4981 gaagagcttc gccagcgtat tggagatttg gcttttgagg tgactcagca tgcagcgacc
     5041 gaaagagcct ttacaggtca gtatgatgat ttttttgaga aggggattta tgttgatgtg
     5101 gtgagcggag aggtgctctt ttcctctttg gataaattca attctggctg cggctggcct
     5161 gcattttcta agccgattca gcatcgtatg gtaaccaatc accatgattc atcacatggc
     5221 atgcggcgtg ttgaggttaa aagccgcgag gctggctccc atttggggca tgtttttaat
     5281 gatggcccta aggaggcagg aggcttacgc tattgcatta actccgccgc gctgaaattt
     5341 atcccctatg atcaaatgga gcaagagggc tacgccgaat ggttagggat ttttgataag
     5401 agctaggaat tgctagcggc caatgaaaag gtagagctct tagccaatgc tagtggctaa
     5461 atcaaagaaa taaaaaggtg gctaaagtac atagaaaaaa gaggtaagca gattggcagg
     5521 tggtcaatct gctttttgtg aggagacttt cagcctgctt tgcgctaaaa agtatgaaac
     5581 caataaacca cctactatgc gggtgtgtgt cggtggttag cttaagtttt ttcagttcgg
     5641 ttttacaagc ttctctaaaa ggactataat agctaatgga aaaggagatt catatgctaa
     5701 catctttaga aaaattaccg ggcgttttac tgtgcttgct gttagcactg cctgcctggt
     5761 atttgggaag cttatttcct attattggag cgccagtttt tgctatttta ttgggaatgc
     5821 tattggcgct tgtctatcag aagcgtgact acactaaatc tggaatcgca ttgacgtcca
     5881 aatatatttt gcagctggct gtggttttct tgggctttgg cttaaacgtg acacaggttt
     5941 tagtggttgg cttgcaatcc ctgccgatta ttgtagtaac gattgtgact gccttgggca
     6001 taagctattt gttcaaaaga tggttaaggc taccagccaa gacagctatc ttagttggtg
     6061 tgggctcgtc tatttgtggt ggctctgcta ttgcagccac agctcctgtc attgatgcgc
     6121 aggacgatga cattgccaag gccatttcgg ttattttttt gtttaatatc ttggcggcct
     6181 tgctatttcc agctttgggt cagatgcttg gcttatcaaa tcatggcttt gctatttttg
     6241 ctggaacagc agtcaatgat acctcatctg taacagctac agcgacagcc tgggacgcta
     6301 ttcaccagtc taatacgcta gatggggcaa ccattgtcaa attaaccaga acgctggcta
     6361 ttattcccat aacacttggc ttatctattt accaaaccaa gagcaggcag gcacatacga
     6421 cagagggttc ctttagcctc agaaaggctt ttccgacctt tattgtcttt ttcttgctag
     6481 cttccttgat aaccaccttt gctgctagct taggtctgcc aatggcaatc tttcatcagc
     6541 ttaagctact ctcaaaattc tttatcgtta tggccatggc agcgatcgga cttaatacca
     6601 atctagtgac cttagtcaaa actggtggta aggccatttt gctgggtggg atttgctggc
     6661 tagcgatcac atcagttagc ttagcaatgc aggcagcttt ggggagctgg taactgatga
     6721 gaatagctgg tgatacgctg ctttatagga aaagcaaagc ccttgctgct cctaaaaaag
     6781 cttgttagag cagctcactt agctgttaag tgtggcttgg tggggtgtaa gtaggctcta
     6841 tcagttagaa aagccatcag aacaaacgct atcattaagc tgaagccggg gaaactcggc
     6901 ttttacgtta tgcagaattg tctacatatt gaataggatt atccatttta aaaacgtttt
     6961 catttgatag aatacaatta tagcttggtt attagggtaa acgagattga acttcttatc
     7021 tggtttagct taagtaaaaa agcagttgga ggaagcatga aacgtaaatt tttaattggt
     7081 agtcatggga gaatggccag tggattgaaa agctctattg acattttggc tggtagaggt
     7141 caggaattac aagtcattga cgcttatatt gatgatagtg attatactga gcaggtattg
     7201 acctttatcg aagatgtagc agctgacgag caggcactga tttttacaga tttattaggt
     7261 ggcagtgtta atcaaaaaat agtaactgcc ctaatggaca gtggcaagga aaatatcttt
     7321 ttgatttcaa atagtaatct tgcagccttg ctatcgttga tgtttttaaa gccagaagaa
     7381 gagctgacaa aagacgagat tgtagcaacg attaacgatt ctcaggtgca gctggtggat
     7441 ctagctccag cgacagccgc agaagatgac ttttttaatt gaggaggaaa aatgaaatga
     7501 ttacacaaat tcgtgttgac gacagattga ttcatggaca ggttgctgtt gtttggacca
     7561 aggagcttaa tgcccctttg cttgtggtgg ctaacgatga ggctgctaaa aatgagatta
     7621 cacaaatgac tctaaaaatg gcagttccta atggcatgaa attattgatt cgctctgttg
     7681 aggactctat caaggttttc aatgatccac gcgcagtgga taagcgtatt tttgtcattg
     7741 tcagctcgat taaggatgct tgccagattg caaagcaggt gaaggactta gaggctgtta
     7801 acgttgcaaa tgtagggcgc tttgacaagt cagacccagc aactaaggtc aaattggctt
     7861 caagcctatt gttaaatccg gctgaattag aagcagcaaa agagctggtt agcctgccta
     7921 acctagatgt tttcaatcag gtactgccat ctaatagcaa ggttagcctg agccagctca
     7981 tcaaataaag aaaggtgtaa tgactatgtt agtaccagca acaatggcag ccttagctgt
     8041 attgatttgt ttcgggggaa attatttaac tggccaaagc atgatggaaa gaccgcttgt
     8101 ggttggtttg gtgacaggat tgctcttagg agatatgaag gtcggtatct tgatgggagc
     8161 gtcactagag gcacttttcc taggaaatgt taacattggt ggtgtcattg cagcagagcc
     8221 tgtaacagca acagctatgg caacgacctt taccatcatt tcacatattg atcaaaaagc
     8281 agctatgacg ctagctgttc cgattggcat gctagcagcc tttgtggtca tgtttttgaa
     8341 aaatgttttt atgaatatct ttgcgccaat ggttgataag gcagcagcgg caaaccatca
     8401 gggcaagctt gtcatgctgc actatggcac atggattgtc tattatttga ttattgcctc
     8461 tatttccttt atcggtatcc tagttggaag cggacctgtt aacgcctttg ttgagcatat
     8521 tccacaaaat ctgatgaatg ggctaagtgc agctggtggt cttcttccag cagtcggatt
     8581 tgccatgctg atgaagctct tatggacaaa taagctagca gttttcttcc tattaggctt
     8641 tgtgttgaca gcttatttga agctaccagc agtagctgtg gctgcacttg gtgcagttat
     8701 ctgtgtgatc agctcgcagc gtgatttaga gttagatgct attactaagg gagctatcag
     8761 taaccaaagc agctttgact ctaaagaatc agaagaggag gacttctttg catgagatct
     8821 caagacaatt taactaaaga agaaagaaaa atgctacgct ctgttttctg gcgttcatgg
     8881 accatgaatg ctagtcgtac aggagctacg caataccacg ctgttggggt tatctatacc
     8941 ttgttgcctg ttatcaatct cttttataag acagataagg ataaggcaga cgctcttgtt
     9001 cgtcacacca cttggtttaa tgcgaccatg catattaata actttatcat gggcttggtt
     9061 gcctcaatgg aaaagaaaaa cagtgaggat ccaacctttg acgctagtgc tattacagcg
     9121 gtcaaggctt ccttgatggg acctatttct ggtgttggag attccttttt ctggggtatt
     9181 ttgagggtca ttgcagctgg tattgggatt tcacttgcta gcacaggctc agcgatggga
     9241 gcagtagtct ttttacttct ctataatatt cctgctttta tcattcatta ttatagcctt
     9301 tatggtggct attctgttgg tgctggcttt attaaaaagc tttatgagtc tggtggtatt
     9361 aagattgtga ccaagacctc aagcatgctt gggtcaatga tggttggctc catgacagct
     9421 tcaaatgtga agtttaagac cattttaaca gttgctgcaa agggagccaa ggaagcagcc
     9481 tctatccaaa attatttgga tcagctcttt attggagttg tccctctttt agtaaccatg
     9541 accgcctttt ggcttttgcg taagaaggtg aacattaact ggattatgtt tggcattatg
     9601 ctattgggta ttgttcttgg tcttttaggt atttgctaat aatctcctag catcaaggat
     9661 aggtaaggca gggacttctt gctttgctta tccttttttg tagtgagggc tgctgaaata
     9721 gccacctgct tgcttaaatg gcttatggat ttgttagata gattaagatt ttcttagctt
     9781 tgagaaatga tttggtataa tagaaggaaa taagggaaaa ggctgcctat ggaagaaaga
     9841 tttaaaaagc gattgcagga tgatatttca catcattttt cacaccaatc attgattttg
     9901 tccattttac tgattggact ctttctcatt ttttcattgg cacctcagca aattgggctg
     9961 tatcaagatt tgaaggctgt tgaacatagc tatcaccagc tgattcggca aaataaggcg
    10021 cttttaacgg agctcaatca gcatattctg accaaatttg tgaatcatca gctgagctct
    10081 tctgacctta gcaaacaata ttatcaccta agaaaccgct cacaaagcca atcagagctg
    10141 ctggtttttg atgctaacag tcacatgctg tttgctagta atcagcatct gggaaatttt
    10201 tttcgcaatg ctgtctatat gacagaagtc ttaaaaaaag caaggcaaag gagtagcttc
    10261 ttgaggatca gtatggataa tgaggagggg cattatttac tgctgataaa gcctattaag
    10321 atagatcatc aggttaaggg ctattcgctt cttgtgatga atggtaagga ttttcttcag
    10381 ctatcacatc agattgcttc agattttgtg attgcagatc agtttgacaa tagctttgcc
    10441 tttaccaatc ggacctttat gacctcaagt ctgaataagc ttgacagtca ttttcttaag
    10501 ggctatttta tctttcacga gcatcgtgcc tttatcctaa gaaaggtcgc tcttagtcct
    10561 tctatcactc tttacagcta ccgccctttg attccagttt ctattgcact cttgttttca
    10621 ttgatgtcct ctgtcatgat ttatgctatt ttgtattgga agtctaaggc tctggcgacg
    10681 cagattgctt ctagcaattc agcagcgatc aatcagatga ttcttgatat gcaggccatc
    10741 tcaaggcagg aaaaaaatgc cattgacctg caaagtcaag atgaatttca atacctgtcg
    10801 gttcagatca atcagatgat tagccgattg caggcacttc atcagaagac cctagcctta
    10861 gaaaagcaaa atgtgagttt tgaaaaacgc atgctggaag cccaatttaa ccctcatttt
    10921 ctctataata cacttgaaac aattttgatt acaagtcatt atgacagtga cctcacagaa
    10981 aaaattgtcc ttcagctaac caggctgctt cgctatagct tagacgaatc acaggaggct
    11041 gtgtgtctgg gagaggattt ggctgtctta gaatcctatc tgttgattag ccagattagg
    11101 tttgaagagc tgcgctacac gatagctgtt gaaccagccc tagagaccct aagggttccc
    11161 aaattatttt tattgccatt gattgaaaat gcgatcaaat atggtctgcg ctatcgccat
    11221 gaccttgtga ttgagatcag cgtgagacag cttgctgatg gaatttactt tactgtagca
    11281 gataacggtc ctggaattag tcaaaaaagg caggccgata ttaaagagct cttgcattca
    11341 gaggattcac atcatggctt ggtcaattct tatcgtcgac tcaagcatca atttataaaa
    11401 gttgaattga tcttttgtca aagagatgag cgctttttac taacctatat ggttaaggag
    11461 taacagatgt ataagctact aattgttgaa gatgagcata ttattcgcaa atggcttcgt
    11521 tatgcgattg attatcatgc gctcaatatc cttgttatcg gagaagctaa ggacggtcag
    11581 cagggggcta agctgattgc agaggctaag ccagatattg ttttgacaga cattaacatg
    11641 ccgattatga ctgcctttga gatgtttgag gccacaaaag agcagtccta tgctaaaatc
    11701 attttgtctg gctatgctga tttcgctaat gcaaagtctg ctatccatta tggtgtgctt
    11761 gagtttttga ccaagccctt ggaaaggcag gccttacatg attgcttgct aactattatc
    11821 caaaagctgc aacagcagtc tcaagagcag gagctaagcc agcagcagga ttacctcaaa
    11881 ctgccacagc ctaatgacca attgcctgat gttgtccaag aaatgctcag ctggatccat
    11941 gagcattacc aggataaaat catgattggt cagttggctc acgatctggg ctatagcgaa
    12001 agtcacctct atcatttagc taaaaaatac ctgaaaatga cttttagtga ctatatcaac
    12061 caataccgcc tgaatcgagc aattcaattg ctgattgctg agccggatgt gatggtttat
    12121 cagcttgcag aggctgttgg catttatgac taccgctatt ttgatcgtgt gttcaaaaaa
    12181 tatttaggac aaacggtcaa ggatttcaga gaaacggtat tacaccagag atcagatagg
    12241 agttcattgt gacaagaaaa aagctgctat tagcaatggc aatagtgata ctaggtgtga
    12301 ttggctctgg cttgtatgct atctggaggc atcaagcagg accagctccc agcaaaccaa
    12361 gagaattggt tgttttgaca cccaacagtc aaaatatcct aacaggtacg atcccagcct
    12421 ttgaagaaaa atacggcatt aaaatccgtc tgattcaagg aggcacaggc cagctcattg
    12481 atcgcttgca aaaggacaag gaccagctcc atgcagacat cttttttggg gggaattaca
    12541 cacaatttga gagtcataag gagctatttg agccttacct ttcaaagcat attggctttg
    12601 tattgcctga ttacctgctg caaagcgagg tcgcaacccc ctatacgctt aatggaagtg
    12661 ttctcattgt gaataatgaa ttggcaaagg acatggttat taccagctat gaggatttgc
    12721 taaagccaga gctaaaggga aagattgctt ttgcagaccc caacacctcc tctagtgcct
    12781 tttctcagct gaccaatatt ctcttagcca aggggggcta cactaacccc aaggcttgga
    12841 gctatatcaa gcagttgatt catagcatga attcaatcaa atctgctagc tcatcagatg
    12901 tttatcagtc agtagcagaa ggaaagatga ccgtcggtct tacctatgag gacccctgtg
    12961 ttaacctttt aaagagtggt gccaacgttt ctattgtgta tccaaaggag ggaacggttt
    13021 ttttaccctc agcagttgcc attgttaagc aatctaaggc caaggctgat gccaaattgt
    13081 ttattaatta tatgttgtct ttagatgtgc agcgggcctt tggtcaatca accagtaata
    13141 ggccaattcg aaaggacgct aaggccagtc aagacatgaa gcctttagat gacattatca
    13201 cgctaaagga agactatgat tatatcacaa gacataaaaa ggatatttta gaacgataca
    13261 atcaattgag aaagaccact gactaaatgg ctttgttata tgaaacagtt catgctgtgc
    13321 tgcacctgaa tcgttagctg ctttgtctag ctttttgagg tcaatctctg cttgggctgt
    13381 tttttatgtt accataaccc actgcatttg tttagaaagt caagcgagat cttaatagcc
    13441 agttataata ggtctttgag agggagtctg agcttgcttg aggtggcaag aagatctgtt
    13501 ttgacgtcaa atggctgaat ttttggtaaa atgatagcat gaatgaactg ataaaacaca
    13561 agctagagct tttgccagat agtcctggct gttatttgca taaggataag gctggcacta
    13621 ttatttatgt tggcaaggcc aaaaatctga gaaatcgcgt acgctcttat tttcgaggaa
    13681 gccatgatac caagacagag ctgttagttt ctgaaatagc tgattttgag tttattgtca
    13741 caggatcaaa tacagaagca ctcttattgg aaatcaattt gattcaagag aacatgccca
    13801 agtacaatat caagctaaag gacgacaagt cttatccctt tatcaagatc actaacgagc
    13861 catttccaag actattaatc acacgtcaga ttaaaaaaaa tgacggcctg tattttggtc
    13921 cctacccaga tgcttacact gccactgagg ttaaaaagct gctagaccgt atttttccct
    13981 ttaaaaaatg caaaaaccct gttaacaagg tctgctttta ctatcattta gggcaatgtc
    14041 aggctcacac gatttgccat acagacaagg cttattggga cagcttggtt gctgatgtca
    14101 agcagttttt aaacggtaag gacgacaaga tcattgatga tttgcgctcc aagatgcttg
    14161 aagcttcgca caatcaagaa tttgaacggg cagctgaata tcgtgatttg atttcaggta
    14221 ttgccaccat gcgaaccaag caaagggtga tgagtaagga cttgcaggat agggatattt
    14281 ttggctattt tgttgataag ggctggatgt gtgtgcaggt cttttttgtc cgtcagggta
    14341 agctcattca gcgagatgtg aatatgtttc cttattacaa cgaagctgaa gaggattttt
    14401 tgacctatgt cgggcaattt tatagcgacc aacggcattt gatccctaag gaggtcttta
    14461 ttccagagac gattgatgag accttggttg cagccattgt tccagcaagg attgtcaagc
    14521 cgcagcgagg ggaaaaaaag cagctggtcg ccttagcaac taagaatgct cgggttagcc
    14581 ttcagcaaaa atttgatttg ctggaaaagg atttaagaaa aacaagtggt gctattgagc
    14641 atcttggtca gctgttaggc attgaaaagc ctgttcgtat tgaggccttt gacaattcaa
    14701 acattcaggg cacaagtccg gtagctgcga tggtggtttt tgtcgatggg aagcccagca
    14761 agaaggacta tcgcaaattt aaaatcaaaa cagtgattgg tccagatgat tatgcgagca
    14821 tgagagaggt gatttatcgt cgttatagcc gcgtgaagca tgaagggcta caggcacctg
    14881 atttgattat tgttgatggt gggcagggtc aggtcaaggc tgctcgtgat gtgattgagc
    14941 accagctagg ccttagcatt ccagtagctg gtctgcaaaa aaatgacaag caccagaccc
    15001 atgaattgct ttttggtaac cccttggcag tggttgagct gccgagaaat tcagaagagt
    15061 tttttctgct gcatcgtata caagatgagg ttcatcgctt tgccattacc tttcacaggc
    15121 aggtcaggag taaaaatgcc ttttcatcaa agctagatca cattgcaggc ttagggccaa
    15181 aacgcaaaca gctactactc aagcgattta aaagcatgac tgctcttgaa caggctagtc
    15241 ttgaagaaat tcagcagcta gggattccaa aaacagtcgc tgaggcactg tttgatcacc
    15301 ttacctcaaa aagtgaggtc tgaattggcc ttgtcaggag ctcaagcagt ctgaattttc
    15361 ttgacaaaag tgaaaaaata gctgaaacca gtttcaaaaa atgatagaat gatactacaa
    15421 cataaaagaa ttagatagga agcatttgca gtgaaatttc tcgaattaaa caaaaaacgc
    15481 catgctatta aacggtttaa cgataagccc gttgattata atgacttgcg aacagctatt
    15541 gaggttgcca ctctggcacc aagtgctaac aatattcagc cttggaaatt tgtcattgtt
    15601 gaggaaaaaa aggcagagct ggcaaaggat ctgccgttgg ctaataagac tcaggtagag
    15661 caggctcagt atgttattgc cctgttttct gataccgacc tcattcagcg ctctcgtaag
    15721 attgcccgca ttggggtcaa gtccttgcct gataacttga ttggttatta catggagacc
    15781 ctgccgccac gttttgctac ctttactgag acccaaaaag gcgaatatct ggccattaat
    15841 gctggcttgg tggcgatgaa tttggtcctt gccttaacgg atcagaaaat ggcctcaaat
    15901 attattttag gctttaataa aaagctaact aatgagattt tagatattga tccacgcttt
    15961 cgtcctgaat tattgataac tgtggggtat agcgatgaca agccagagcc tagctatcgc
    16021 ctaccagtag acgaaatcat tgaaagacgc taagatacac aactactcgt ccagctagcc
    16081 tataagtttt tggatttagg aggatagcga ggcaacacat aaaggagaaa aagatgacaa
    16141 caattgattt taaagcagag gttgataagc gcaaggaagc tatgctagag gatctatcaa
    16201 acctattaag cattaattcc gagcgagacg atgctaaggc agatgccaag cacccatttg
    16261 gtcctggtcc ggttaaggcc ttggagttct ttcttgccat ggcagagcgt gatggttacc
    16321 aaacgcgtaa tattgataac tatgctggtg attttgaatt tggtcaggga gatgaggttt
    16381 tagggatttt tgcccattta gacgtggtac ctgctggtag tggctgggag acagaccctt
    16441 ataagccggt gattaaggat aatcgtatct atgcgcgtgg ttcatctgat gataaggggc
    16501 caaccatggc ttgctattat gccctgaaaa tcatcaagga attaggcttg ccagtttcta
    16561 aaagggttcg cttcattgtt gggactgatg aggagtcagg ctggggtgat atggactatt
    16621 attttgctca caatggcttg aagaaccctg attttggttt ttcaccagat gctgaatttc
    16681 ccattatcaa tggtgagaaa ggaaacatta cagaatacct tcattttgtt ggtcaaaatg
    16741 ctggagcttt tgtccttcat cgcttccaag gcggtttacg tgaaaatatg gttcctgaat
    16801 cagcgacagc tctgatcagc tcaccgcatg agcttaatgt tatcgaagct tctttggagc
    16861 aattcttatc tgagcacgca gtgacaggat ctgtcaaaga ggctgatggg ctattggaag
    16921 tgaccattat tgggaaatct gctcatggct ctacaccaga ggctggtgtt aacggtgcaa
    16981 ccctgctggc taaattctta aatcaattta gctttgatgg cgcagccaag gcttatttgc
    17041 atattgcagg tgaggtgctt catgaggatt tcacagcaga aaagcttggc ttggcttata
    17101 cagatgacaa aatgggtgcc cttagcatga atgcaggtgt ctttagcttt gctaaggatt
    17161 cagatgacaa taccattgcc ttgaatttcc gttatccaaa gggaaccaat gcagcagtgc
    17221 taaaggcagg gcttgagcaa ttaccaggct tgactaaggt taccttatct gagcatgaac
    17281 acatccctca ctatgtgcca atggacgatg agctggtctc aaccctccta tccgtctatg
    17341 aaaagcaaac aggactcaag ggctacgagc aggttatcgg tggtggcacc tttggacgct
    17401 tgcttgagcg tggtgttgcc tttggtgcga tgttcccagg tgatgaaaac acaatgcatc
    17461 aggccaatga atacatgcca ttagacaata tttaccgatc agctgccatt tacgccgaag
    17521 ctatttatga attgatcaaa taagagattg aacaagctct ctgtctaaga tgagccttgc
    17581 taatattaac gaataaaagc cttatgaagt tagtcgttta atgagacttc ataaggcttt
    17641 ttgtttggcg tcaagccatt atttacaaag agaaatgcca cagtggatca tcttttgaaa
    17701 agtccttgta aaaacagacg taaaactagt tttagaggag acattgatag gcagtcatgc
    17761 ttatcaagag atcttgtcta gcagttatgg caaaaagatc agtgaactat tattttccaa
    17821 ggcagaactg actgaacaat tgagtaatta attcatcagg tgcggcatcg cctgtgattt
    17881 ctcctaggat ttcccaagct ctggtcaaat caatctgtaa gagatcaacc ggcattccta
    17941 aagcaagtcc ttcattgaca gcctctaagc tttgtactgc ctgctcaatc aaggaaatat
    18001 gacgagcatt ggataggtaa gtcgcatctt gctctattag cccagtatga tcaaagaaaa
    18061 tctgattgat ccggtcttcg atcaggtcaa tgttttggtt ttgcaaaact gatattggga
    18121 tcgcctcttc tggaagctgg tctttttcaa tgacctgctc cagatcggtt ttattgagga
    18181 gaataatgcg attgctatcc tgactaaggg ctagcagagc cttgtcctgt tcggtcagct
    18241 tttccgaagc attgagaact aaaaggacca gatcagcctc ctgtagggct tttttagacc
    18301 gctcaacacc aatttgctct actaaatcat ctgtttctct aattccagca gtatcaacta
    18361 gctttagagg aattcccttg atattgacat attcttcaat gacatcacga gttgttcctg
    18421 caatatcagt gacaatggcc ttatcctcac gtaacaaggt attgagcaga ctagactttc
    18481 ctacattcgg tcggccgata atagctgttg acaagccctc acgtaggatc ttcccgcgct
    18541 tggcagtacg taggagctgc tctaaaagtg tttgaaattc tcgcgttttg tcacgcaaaa
    18601 gagcagtggt catttcttcg acatcatcat attcggggta gtcgatacta acctcaacct
    18661 gggctaaggt atttaggatt tcttgacgtg tgtcgctgat gagctgtgat agggagccgt
    18721 ctagctgctt gatagcaata gacatggcct tatcagtctt tgcacgaatc agatccatga
    18781 ctgcctcagc ctgtgttaaa tcaatacggc catttaaaaa agcacgcttt gtaaattcgc
    18841 cgggctctgc cattcgagct ccctgtttaa tgaggagctg taaaatgtca tttgtcaccg
    18901 caataccgcc atgggtattg atttcaatca cgtcctctct ggtaaaggtt tttggcgcca
    18961 gcatgactga taccatgacc tcatcaatca cttcacctgt gcttggcttg ataatatgac
    19021 catagttaag ggtatgtgag gcgactgttg ttagatcttt tcctttaaag atcgatttag
    19081 caatgtccag agccttggta ccagacaagc gaacaatgcc aatagctcct tcacctaacg
    19141 gagttgaaat ggctgcaatt gtatcaaatt ctttagttat actcatgcct tctattgtag
    19201 aacaagtcag catagaaagc aaggtattgc attagctgct cgttgtcgtc attcttgtct
    19261 agtggcaaag cctcaaaagc agttgtaaac agctaaagct atgattaaaa agccttgtat
    19321 ggtaagtaca ggataaagcc aaaaagctga tgagttttag ataaacatac aggctcgaaa
    19381 agccctatta aaccgacagc aacaatcctc acacagtata gttgacttaa ctacctgatg
    19441 tcatttctgg ctgtttttat aatgacaatg gcaatatcgg ttattttgac tatgctgggt
    19501 gcttgtatcc tagtggactg actgacaatc agggcttctt tttcaaccac gaaaacatta
    19561 aaaaagtctg gtttggaggc tatattgacg atagtgaaag agaagctcaa gactttttta
    19621 aaaaagaggc aggctatatt aaatatccta aacttagtat agataatagc actagatagc
    19681 attaatttaa gtatataacg ttatgattat ggttggatta gttc
//
LOCUS       DARYLJ010000039        19649 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYLJ010000039 DARYLJ010000000
VERSION     DARYLJ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19649
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            18..98
                     /locus_tag="TU746_001435"
     tRNA            18..98
                     /locus_tag="TU746_001435"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="TU746_001436"
     tRNA            105..175
                     /locus_tag="TU746_001436"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="TU746_001437"
     tRNA            187..259
                     /locus_tag="TU746_001437"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="TU746_001438"
     tRNA            268..339
                     /locus_tag="TU746_001438"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            358..441
                     /locus_tag="TU746_001439"
     tRNA            358..441
                     /locus_tag="TU746_001439"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Leu,seq:caa)
     gene            complement(785..1915)
                     /locus_tag="TU746_001440"
     CDS             complement(785..1915)
                     /locus_tag="TU746_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0891772.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            2480..3646
                     /locus_tag="TU746_001441"
     CDS             2480..3646
                     /locus_tag="TU746_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0891773.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQ
                     GQRGEKGEQGQRGEKGEQSQRGEKGEQGKDTKPSAPKAPEQSPAPQVPKTSEQQSASP
                     KVPAPKSAPSKSAAPAAQKGILPATGETNHPFFTLAALGVIASAGLLTLKRKNN"
     gene            4140..4664
                     /locus_tag="TU746_001442"
     CDS             4140..4664
                     /locus_tag="TU746_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL0891774.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            4879..5730
                     /locus_tag="TU746_001443"
     CDS             4879..5730
                     /locus_tag="TU746_001443"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL0891775.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            5800..6243
                     /locus_tag="TU746_001444"
     CDS             5800..6243
                     /locus_tag="TU746_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL0891776.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            6246..6965
                     /locus_tag="TU746_001445"
     CDS             6246..6965
                     /locus_tag="TU746_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL0891777.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKSRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            6958..7767
                     /locus_tag="TU746_001446"
     CDS             6958..7767
                     /locus_tag="TU746_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL0891778.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(7802..9058)
                     /locus_tag="TU746_001447"
     CDS             complement(7802..9058)
                     /locus_tag="TU746_001447"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL0891779.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            9163..11463
                     /locus_tag="TU746_001448"
     CDS             9163..11463
                     /locus_tag="TU746_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0891780.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            11725..15291
                     /gene="rpoB"
                     /locus_tag="TU746_001449"
     CDS             11725..15291
                     /gene="rpoB"
                     /locus_tag="TU746_001449"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL0891781.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            15382..19017
                     /gene="rpoC"
                     /locus_tag="TU746_001450"
     CDS             15382..19017
                     /gene="rpoC"
                     /locus_tag="TU746_001450"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL0891782.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(19109..19319)
                     /locus_tag="TU746_001451"
                     /pseudo
     CDS             complement(19109..19319)
                     /locus_tag="TU746_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5502 a         3750 c         4765 g         5632 t
ORIGIN      
        1 gtaatttaat atgttttgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctgaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttcag
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttagttttat acttaaagcc
      361 ggcgtggcgg aattggcaga cgcgctggac tcaaaatcca gtgtccgcaa ggacgtgccg
      421 gttcgacccc ggccgccggt atagtttaaa aatattgaaa aaacaaggtt tgtaaacctt
      481 gtttttttgt tttatgactt gatgtcagag gatcagattg gtcctctcta gatgttaaag
      541 gtaatgagaa tcttggcttc aaagctccta aatccaaagc attgcgcttg atgtctttga
      601 tcacctgtta gtggcgtgca gcttagcgtt tgaatttgga ataaggttgc tccaaggcat
      661 gtgtgatgtg agctttggat actaggactt ttagccaatt ctttgtgggt gagctttttc
      721 tttacgtttg gttttgatta atgtcgcaat atcagttatc atgtgttctc tggttaatga
      781 cgctttagca aatatcgtat tgtcttagca tcttgtttga gaaataaagc agactaatta
      841 agataagcga acccaaggca agtgttggga tggttacggt ataaaaagca ctgaaaactt
      901 caccaagatg ctcatcagga atctcagttc gtaaaatagg tttttgggta acatgcgtta
      961 ttccgagaaa tagacaggaa agaaaccaaa gaagcaacaa accaaaacgg ttggggacta
     1021 atgctgtaag gccaataccg gtgcccaaaa gggtagttgc tagccaaaaa gcttttccta
     1081 cacttaactt ttgcaagaca aggttagcaa caaaggttgt tcctaccagg gttccgatag
     1141 cacttacaga tactaagagg ccataaaaag ctgaattccc tacctctctt gctattaata
     1201 actgatagac atttaagctg gcaaaaagga aattagcgat agcacctccc aatgtgatgg
     1261 ctaacaccac tttattgtgc cagataaagc gcaagccact taaaaagtct gttcgttcat
     1321 ttgtttgttc aattatttct ttaaatgcta ttcttctaaa aaataggatt gaacctaaga
     1381 aggtaacgat attaatgaaa agcaaaggaa tgtagctgat cacagaaagc aaaaagccac
     1441 tgatggcagt aaaaacataa tctgttccat tataagccac tgacatatac atttctgctt
     1501 tagctagatc tttagtagga atgagtttag gtacaagagc atcttgaaca gtataggtat
     1561 tcaacccaac catagaagcc agaaaaacac aactaaaaat aatggttaag ctaagacttg
     1621 cgtgtatctc tcttaaggac attcctaaaa taatacctaa gacagccaat aattgggccc
     1681 actccagaat cactagcagg ttcttcttag ggtacgaatc aatctttttt ccaaagataa
     1741 aggagaaggt gtttggaata aaaatgagaa agttcaataa tccaacatac caagtactat
     1801 tagtggtttc tagtacatac caggacagca ctagggtata aatcgagtca ccgcaattgc
     1861 taatcagtcg ccccagaaat aaccggcaaa aatcattata tttccttaat atcatattgt
     1921 atcctttgat aaagagttta aacatctttt atattatagt atcagatgat aaaaaatcac
     1981 tgaatgatag ctgtgtttga tgtttgcaac attttaaaat atctttgcaa aaatcatacc
     2041 tagacacata caatcccaca taagttttaa aagcattcaa ttgcctttta agatctttat
     2101 gagtcatgtt tgtaaagata tcctcttgca acagatctct taatctctaa ttgtatccaa
     2161 taagaagcag ctttgtcaat acggaagccg aatagtcttt ttgcctttcc ttgtcagctg
     2221 ggcaatcatg agggctttgt gctttgatct tttgcatcta taaaagggtg aatctattga
     2281 tgaggtgtta tcggtagtgg ggcctactga tgtcaataac tgacgtcaga taattacctc
     2341 tttaattaga aaaaaaaaaa aacgaaacta cggagagaac ctaataactg gctatttctt
     2401 gatataagcc agcgtgttaa aatcttcttt gggagaaaat ttagaaaaaa ataatatttc
     2461 tatcactaag gagagaaaga tgacaactaa agaaaaacaa acaaaactaa tgcgcaggta
     2521 tggcattttc tcggtagtcg ttgccctaac agctctagca ggtctaggag cagctaatga
     2581 agttaaggca actgctaaaa aatctttaaa tgagttacct aatccagtag aaattattca
     2641 atataattca acaagaacta ctgatagaga agctagaaag tatcttaatc aattatatga
     2701 gtttttgaaa ccttatttag gaagtttaga agaagaagct caaaaaggag ggccacaagg
     2761 acctgtggga cctgctggtc ctagaggtga acgcggagaa ccaggaccta aaggagaccg
     2821 aggtcctgag ggccaaagag gtgagcaagg cccagcgggg cctattggac cccaagggcc
     2881 tcgtggtgac aagggtgaaa ctggagaaat tggacctagg ggagaacaag gtccgaccgg
     2941 tcctactggt aagccaggag agcgtggccc taagggtgac agaggcgaac gcggcgaaaa
     3001 aggcgagcaa ggccagcgtg gcgaaaaggg cgagcaaggc caacgtggcg aaaaaggtga
     3061 acaaggccaa cgcggtgaaa agggcgagca aggccaacgt ggcgaaaaag gtgaacaagg
     3121 ccaacgtggc gaaaaaggtg aacaaggcca acgcggtgaa aagggcgagc aaggccagcg
     3181 tggcgaaaaa ggcgagcaag gccaacgtgg cgaaaagggc gagcaaggcc aacgtggcga
     3241 aaaaggtgaa caaggccaac gcggtgaaaa gggcgagcaa ggccaacgtg gcgaaaaagg
     3301 cgagcaaggc caacgtggcg aaaaaggtga acaaggccaa cgcggtgaaa aaggtgaaca
     3361 aagccaacgc ggtgaaaagg gcgagcaagg aaaggatacc aaaccatcag ctccaaaggc
     3421 cccggagcaa tctcctgctc cacaggtacc aaagacttca gagcagcagt cagctagtcc
     3481 taaggtacca gcgcctaagt cagcaccaag caaatcagcg gctccagcag ctcaaaaggg
     3541 tatattacca gctacaggag agacaaatca cccattcttc acccttgcag ctctcggcgt
     3601 cattgccagc gcaggcctgc taactctaaa aagaaaaaac aactaaatta gcttttgcaa
     3661 ctttctccta ctaaatgata gcctttagct tgaaggcgat tgattagttt aaaagctgat
     3721 atgagcacta gagaggccct aatggggtct ctttttgctt gcagcagtag atgttttgtc
     3781 ttcctctttc atggggtgat gtagttggtg tgcttttggg ttgagccttt aaggtttttt
     3841 gtaactaata tgatgaggca agtcagctgt gtgtatcacc atatcgttaa ctgagtaaga
     3901 cgcttgggga tcttaactac cagtttgtta gcgtggtgag ctttttgata cgtctcggga
     3961 aaacagatct ttttgtccat tttctatgcg aggcatttta aggtagggaa ttgtagaaaa
     4021 aagaattaag ctaggttggt aattgttgtt ttgtctggac ctggttgttt tggatatgct
     4081 tattgtgata tgattaatat actggatctg gtaatagctg tatcaggagg tgtgtttgta
     4141 tggttgagta ttgggacatt tatacgatga atcgtcttaa gactggtaga ctcatggagc
     4201 gtggagctgc ttttgtagag ggtgcttatc atttagtggt tcacgcctgt gtctttaatg
     4261 acaagggaga aatgctgatt cagcagcggc aaaaggataa agagggttgg cccagctatt
     4321 gggatataac ggtaggcggc agcgctcttg caggtgagac gtcacaagag gcagtgatga
     4381 gagaactgaa ggaggagcta ggacttactc ttgatttagc tggtgtaagg cctcattttt
     4441 caattacctt tgataatggc tttgacgata cttttttgat tttgcaggct gttgatgtaa
     4501 ggaagctagt tcttcagaca gaggaggtac aggctgttcg atgggctagt cgtgatgaga
     4561 ttttagccat gattgatgct ggtattttta ttccctactt taagagcaag attgatatgt
     4621 gctttgagtt agtggggcaa tatggagcga tcaagtggtc atagagactg ctgctgtctt
     4681 agctttgctt gctatgctag tagttgtcgt tttttggctg ctgatctggt gaagcctcac
     4741 gctagtaggg acaaatggtt ggctgttttg atacaaacac gctgtctatg catcattaga
     4801 tactaactgt atttatttga atttttcatg aagattgtgt atatttgata ctataatgac
     4861 atcaaataaa ggagtattat gactgcaatc attgagagag ctcctgcaaa aataaatcta
     4921 ggcttagata ttcaaggcaa gcgaccagat ggctatcatg acctatctat ggttctagtt
     4981 agtgtagatc tttgtgatta tattacagtg gatcatttag aggaggatag gattttattg
     5041 acctctaatt gccctagatt gcctattaat gagcacaatg acgtttacaa ggcggcttat
     5101 ttgctgaaag agcgatttca aatctcaaca ggtgtctcta ttttcttgga taagagggta
     5161 cctgtttgtg ctggtatggg aggtggctca agtgatgcgg ctgcagcaat cagagcattg
     5221 aatcagctgt ggcagctaaa gcttagtccc cgtcagatga ttgacattgg catgcagatt
     5281 ggtagcgatg tgccttattg tctttttgca ggctgcgccc aagtgactgg caaaggcgag
     5341 gtggttaagc caatcaatgg ccgcttgtcc tcttgggtgg ttctagtgaa gccagaattt
     5401 ggcatttcta ctagaacgat tttttgggat attgattgtg agacgatatc tcgagtgccg
     5461 attgaggatc tggtttcagc cattgaggca ggtgattatc agcgcttgct tgcaacgatg
     5521 ggaaattcct tagaggatat ttccattgct aaacggccgt ttattcaaaa ggttaaggat
     5581 aaaatgctgc agtcaggagc agacattgcc ctgatgacag gaagtggtcc aacggtattt
     5641 gccctatgtc aaacagaaaa gcaggccaat cgtgtggtga atagcctgaa aggcttttgt
     5701 aaggaagtct acaaggttag aacgctgtag atcagccttg aagttgcgtc ttttggggcg
     5761 tcatgttata attaactggt taatgaggag agggaaatca tgacaatttt agaaaaaaag
     5821 cttgataatt tggttaatcg tattttgtta aaggctgaaa atcagcatga gctgctcttt
     5881 ggggcttgtc agagtgatgt caaattaaca aatactcagg agcatatttt gatgcttttg
     5941 tcacaggaaa agctaaccaa tacagatttg gcaaaaaggc taaatatcag tcaagcagca
     6001 gtaactaaag cgattaaagg cttgatcaag caagaaatgc tagcaggaac aaaggatacc
     6061 gttgatgctc gagtaaccta ttttgaactg actgatctag caaggccaat cgctaaggag
     6121 catacacatc atcacgataa aacactagct gtttatcatc gtttgttggc acatttttct
     6181 gcggaggagc aggtgattgt tgaaaaattt atcactgctt ttgcggagga gttagaaggg
     6241 taataatgag atacatatcg gtggaaaatc tctcgttcca gtatgacagt gagcctgttt
     6301 tagagggaat cagctatcat ttggatagtg gagaatttgt cacattgact ggtgaaaatg
     6361 gtgctgccaa gtcaaccctg atcaaggcga ccttggggat tttaaagtca agggctgggc
     6421 aggtgactat agctaaacag aacattcatg ggaaaaagct gagaattgct tacttgccac
     6481 agcaggttgc cagctttaat gcaggctttc cgtcgactgt ttatgaattt gttaaatcag
     6541 gcagatatcc tagaagtggt tggtttacca gactaagtaa gcacgatgag gagcatgttc
     6601 ggacaagctt ggagtctgtt ggcatgtggg atagtcggca taagagaata gggagtctat
     6661 caggtggtca aaagcagcgt gtggttattg cgcgtatgtt tgcttctgac cccgatattt
     6721 ttgtgcttga tgagccgacc acaggaatgg atagtggaac aacagatact ttttatgagt
     6781 tgatgcacca cagcgctcat agacatggta aggctgtttt gatgattaca catgacccag
     6841 aggaggtcaa ggcttatgct gatcgcaata ttcatttgat tagaaatcaa cggcttcctt
     6901 ggcgttgctt caacattcat gatgctgagg ctgatgagag caaaggaggg tcattccatg
     6961 cttgagattt tatcttatga ttttatgcag cgtgctgtta tggctgttgt ggcgatcagt
     7021 atctttgctc cgattttggg tatctttttg attttgcgtc gtcaaagctt gttgagtgat
     7081 acgcttagcc acgtttctct ggctggtgtg gcctttggtg ttgttcttgg tgtttcgcca
     7141 accttcacaa cgattattgt ggtggtgcta gctgccatct tgctagaata tcttagggtg
     7201 gtttataagc actatatgga gatttcgaca gctatcctaa tgtccttggg gctggctatt
     7261 tccttgatta tcatgagtaa gtcaactagc tcttctagta tgagcttgga gcaatacctt
     7321 tttggctcta tcattactat tagtacggag caggttgctg ccttatttgt cattgctttg
     7381 attattttag ccttgacgat attatttatt cgtccaatgt atatcttgac cttcgatgag
     7441 gacacagcct acgtcgatgg cttgccggtg cgtgtcatgt ctgtcttgtt taatattgtg
     7501 acaggtgttg ctattgctct aacgatccca gcggcagggg cccttttggt atcaacgatt
     7561 atggttttgc cagcaagtat tgctatgcgg cttgggaaaa actttaaatc agttattttt
     7621 cttgggatta tgattggctt tacaggcatg ctgtctggta ttttcttgtc ctatttttgg
     7681 gaaacgccgg caagtgcgac cattacgatg atttttattg cgatcttcct tgtggttaac
     7741 ctgctgtcct ttatacgtca aaaataatca tccaaagcaa gattttccta gctgtctgtg
     7801 attagtaggt tagtacagcg tattttttct tgccgcggcg aatgacggtc aactgattgt
     7861 caatgcgatc tgctgtagat aagctgtaat ccagatcctg aagtcgttct ccattgaggt
     7921 agatcgcgcc attttgtaaa tcctcacgcg cctgacgttt tgatggtgaa atgcctgctg
     7981 tgactaacat atccacgata tttaggctgt cttctgcttg aacctgatag ttagggacat
     8041 tgcttaagcc ttgcttaagc tcagctgctg aaaggttttt gatagctcct gcaaaaagct
     8101 gttcggtaat attgagggct tgctggtagg ctgcctctcc atgaaccagt gtcaccacct
     8161 cacgcgcaag tgtcttttga gcaaggcgct catggcgtgc tgcgttgaac tgctcctcaa
     8221 tagcagcaat ctcatcaagt gataagaagg tgaagatctt caggaagcgt accgcatcat
     8281 cgtccataac atttaaccag aactggtaca tctcgtaagg agatgttttt ttagcgtcaa
     8341 gccaaatcgc attaccctct gacttgccga attttttacc tgttgcatct gtaatcaatg
     8401 gcactgtcat cacatgtcca gtcttgtcag cttttttgcg gagcaattcg gtacctgctg
     8461 tcatattacc ccactggtca gagccgccga tttgcagtgt cacattgtgc ttagcattta
     8521 gctcgtaaaa atcgtagcct tgcatgacct gatatgcaaa ttcggtgtag gaaattccgg
     8581 tttcgatacg ttttttcact gaatccttgc tcatcatgta attgatagtg aagtgcttgc
     8641 cgacatcacg aaggaagtca ataaagctaa tctgtgagaa ccagtcatag ttgttgacaa
     8701 gctcagcctt gttttcaccg ttgtcaaagt caagaaagca agagagttgt tctttaatct
     8761 tttggctcca atcaagaacg gtttccttgg tttgtaggat acgctcagcg tctttaaagg
     8821 acggatcacc aatcagccca gttgccccac cgacaagagc gtagggcttg tgtcctgcta
     8881 gctgcaagcg acgtgatgtc aaaatggcaa cgagatgacc aagatgcagg ctatcagctg
     8941 ttggatcata gccagtgtaa taggatactt gcccttctgt taatgctttg acaagggctt
     9001 cttcatcggt cgtctgaaag accaagccac gagctttgag ttcttcaaaa atattcatag
     9061 gctttctcca ttttctttat gatttccgaa tcattatatc aaaaatgact gtggctgtgc
     9121 aagcttaatc aaagtttggt ataatgaaga ttgaggtacg ttatggtgaa atggaaaaag
     9181 aatcaaacaa gcaaaaatca tcagcgatta gaattagttg attttggaac ggtctttttg
     9241 cgcacattaa aattcatgtc gagctttttt tatgtagctg tctttttatt tggcatgctg
     9301 ggtgctggta tggcctttgg ctatttagcc agtcaaattg actcggtaaa aattccaagt
     9361 aaggaaagtc ttgtcaagca ggttgaatca ttgaccatga tgtcacagat tacctattca
     9421 gataatagct tgatttcagg cattgatacg gatctgctta ggacaccggt tgctaatgat
     9481 gcgatttcag acaatatcaa aaaggctatt gtctcaactg aggacgacaa ctttcagcgc
     9541 cataatggca ttgtgccaaa ggcgattttt cgtgcgactc tggcctctgt tttgggcttt
     9601 ggggagtcaa gtggtggctc tacgctgaca cagcagttga ttaagcagca agtcttgggc
     9661 gatgatccga cctttaggcg aaaatcaaag gaaattatct atgcactggc cttagagcgt
     9721 tacatgtcaa aggacgatat tttatcacat tatttaaacg tgtcgccttt tggtcgtaat
     9781 aataagggac aaaacattgc aggtgtggag gaggctgcgc gtggcatttt tggagtctct
     9841 gccaaggatt tgacggttcc gcaggcggcc tttttggcag ggcttccgca aagcccgatt
     9901 gtttattcgc cgtatttgcc gacagggcag ttaaaatcag ccgatgatat ggcctatggg
     9961 attaagcgcc agcaaaatgt cctctacaat atgtatcgaa caggtgtgct gacagaaaaa
    10021 gaatatcgtg attataaggc atatcctatt agcaatgatt ttatcaaacc tgaaacagtc
    10081 actgccaata ctcatgatta cctctactat tctgtcttgg cagaggcaca aaaggccatg
    10141 tatagctatc tgattaagcg agataaggtg cctgctaaag atttaaaaaa tgatgagact
    10201 aaggctgcct atgaggagcg agccttaact gagctgcagc atggcggcta cactgtcaaa
    10261 acaacaatca ataagccaat ccatcaggtg atgcaaaaag cggcagctca gtttggtggc
    10321 ttgttagatg atggcactgg gacagtgcag atgggcaatg tcctaacgga caatgctaca
    10381 ggtgctgttt tgggctttat tggtgggaga gactatgctc aaaatcaaaa caatcatgcc
    10441 tttaatactg ttcgctctcc aggctctagc attaagccga ttattgctta tggacctgcc
    10501 attgatcagg gattaatggg aagtgctagt gtcctatcca actatccgac gacctattcc
    10561 agcggtcaaa aaatcatgca cgtcgatagt gaaggaacag caatgatgcc cctgcaggag
    10621 gcgcttaata cctcatggaa tattccagcc ttttggactc aaaagctgct gcgtgataag
    10681 ggcgttgatg ttgaaaacta tatgagtaaa atgggatatc ggattgctga ttattccatt
    10741 gaaagtctgc cacttggtgg tgggattgag acctcggtag cccagcagac caatgcttat
    10801 cagatgattg ctaataatgg tctttatcaa aagcaatata tggtggctag tatcacagct
    10861 agtgatggat ccgttgttta tcagcatgag gccaagccgg ttcgtatttt ctcagctccg
    10921 acagcaacga ttttacagga gctcttgaga gggccgattt catctggggc aacaaccact
    10981 tttaaaagcc gattagcagg gatcaaccca agccttgcag gtgctgactg gataggtaaa
    11041 acaggaacaa ccgaaaatta taccgatgtc tggctggtct tagctactcc aagggttact
    11101 ttgggtggtt gggcaggcca tgatgacaat acctcgcttg caccactgac gggatacaat
    11161 aataattcaa attatatggc ttatttggtt aatgccatca gtcaggctga tcccaatctt
    11221 tttggccttg gtcagcggtt ttcactggat cctggtgtta tcaaggcttc tgtcttgaag
    11281 gccactggtc taaagccggg tacagtgacg atcaatggcc aaaccatctc catcggtgga
    11341 gagctaacaa ccagcctttg ggctcaaaag ggacccggag caactaccta taggtttgcc
    11401 attggtggaa cagacgcaga ctatcaaaaa gcctggggag gttttagtgg tagaagaaat
    11461 tagttgtatt ttccagacaa atagtgtata atatctataa ctatttgtcg tctaatctag
    11521 ctgaaatatt gtccagctag aaagaacagc agttaaatca cactgataag gtccgattta
    11581 gctgctcttt ttgtgcctat ttttagataa aaatcaattt tgtaacaaaa atttaaagat
    11641 tctaaaaata ccacttaaga caaatattga tgttgcaatt gtttgcttga tagcaaagct
    11701 taaaaagaaa aaggagctaa aaacttggca ggacatgacg ttcaatacgg gaaacatcgt
    11761 acccgtcgta gtttttcaag aatcaaagag gttcttgatt taccaaattt gattgaaatt
    11821 caaactgatt cattccaaga tttcttagat tcaggcttga aggaagtatt tgaagatgtg
    11881 cttccaatct caaactttac agacacgatg gagcttgagt ttgttggtta cgaatttaag
    11941 gagcctaaat atacccttga agaggctcgt atccatgatg caagctattc tgcaccaatc
    12001 tttgtgacct tccgcctgat taataaggaa actggcgaaa tcaaaacaca agaggtcttt
    12061 tttggtgatt ttccgattat gactgaaatg ggaaccttta tcatcaacgg tggagagcgt
    12121 attattgttt ctcagctggt tcggtctcct ggtgtttatt tcaatgacaa ggttgataaa
    12181 aatggtaagg ttggttatgg ctcaacagtt atccctaatc gtggtgcttg gctagagcta
    12241 gaaactgact caaaggatat tgcttatact cgtattgacc gtacgcgtaa aatcccattt
    12301 acaacgctag tgcgtgcact tggtttttct ggtgatgacg aaattattga tatttttggt
    12361 gatagtgagc ttgttcgcaa taccattgaa aaggatattc ataaaaacca aagcgattca
    12421 cgtacagatg aggctcttaa ggaaatttat gaacgcttaa gaccaggtga gccaaagaca
    12481 gctgatagct cacgcagcct tttgacagct cgtttctttg atgctcgccg ttatgacttg
    12541 gcagcagttg gccgttataa gattaataaa aagctgaaca tcaagacacg tcttttgaat
    12601 caaattattg ctgaaaatct aatagatagt gagactggag agattctggt tgaggctgga
    12661 acagagatga ctcgtagtgt gattgagtca atcgaagagc agcttgatgg ggatttgaac
    12721 aagtttgtct acacaccaaa cgattatgcg gtggtgacag agcctgtgat cctacaaaaa
    12781 ttcaaggtgg tttcaccagt tgatcctgat cgtgtggtga cgatcgttgg taatgctaac
    12841 ccagatgata aggttcgtgc ccttactccg gctgatattt tggctgagat gtcttatttc
    12901 cttaaccttg ctgaaggtct tggaaaggtc gatgacattg accacttagg taatcgtcgt
    12961 atccgtgcag ttggtgaatt gcttgctaac caattccgta ttggtcttgc tcgtatggag
    13021 cgcaatgtcc gcgagcgtat gtctgtacag gataacgatg tgttgactcc acaacagatt
    13081 attaacattc gtcctgtaac ggcggctgtc aaagaattct ttggttcttc acagctatca
    13141 cagttcatgg atcagcacaa cccattgtct gagttgtcgc acaaacgtcg tttgtctgcc
    13201 ttaggacctg gtggtttgac acgtgatcgt gctggctatg aggtgcgtga cgtgcactac
    13261 actcactatg gtcgtatgtg tccgattgaa acacctgaag ggccaaatat cggtttgatt
    13321 aataacctgt cttcatttgg acatctgaac aaatacggct ttattcaaac cccttaccgt
    13381 aaggttgatc gtgtgattgg ccgagtgact aatgagattg tttggctaac tgctgatgaa
    13441 gaggatgagt ttacagtggc tcaggctaat tctaagctca atccagacgg tacctttgct
    13501 gaagagattg tcatgggacg tcaccaaggt aataaccaag agtttcctgc tagtcaggtt
    13561 gactttgttg acgtgtctcc taagcaggta gtcgctgttg cgacagcatg tattcctttc
    13621 cttgaaaacg atgactccaa ccgcgcccta atgggagcta acatgcagcg tcaggctgtg
    13681 ccattgattg atccaaaggc tccttatgtt ggtacgggta tggaatatca agcagctcat
    13741 gattcaggtg ctgcggtaat tgcccagcat aatggtaagg ttgtcttttc agatgctgaa
    13801 agagtagagg tgcgtcgtga ggacggttca cttgatgttt accacatcac aaaattccgc
    13861 cgttcaaact ctggtactgc ctacaaccaa cgaacccttg ttaaaatagg tgatattgtt
    13921 gaaaagggtg actttatcgc tgatggccct tctatggaaa aaggtgagat ggctcttggt
    13981 caaaatccaa tcgttgctta catgacctgg gaagggtaca actttgagga cgcggttatc
    14041 atgagtgagc gtcttgtgaa ggaggacgtt tatacctctg ttcacttgga ggagtttgaa
    14101 tcagaaacac gcgacacaaa gcttggacct gaggaaatca cacgtgaagt gccaaacgtt
    14161 ggtgaagaag ccctcaagga ccttgatgaa atgggtatta tccgtatcgg tgcagaggtc
    14221 aaggaaggcg atattcttgt tggtaaggta actcctaagg gtgaaaaaga cctttctgct
    14281 gaagaacgtc tcctgcatgc tatctttggt gataaatcac gtgaggttcg tgatacctcg
    14341 ttacgtgttc ctcatggtgg tgacgggatt gtacgtgatg tgaagatctt tacacgcgca
    14401 aatggtgatg agcttcaatc aggtgttaat atgctggtgc gtgtttacat tgctcaaaag
    14461 cgtaaaatca aggtcggaga taaaatggcc gggcgtcatg gtaacaaggg tgtcgtctca
    14521 cgtattgtac cggttgagga tatgccatat ctgccagacg gaacccctgt tgacatcatg
    14581 ctgaaccctc ttggggtgcc gtctcgtatg aacattggac aggttatgga gcttcaccta
    14641 ggtatggctg ctcgtaattt gggtatccat atcgcaacac cggtctttga cggagctacg
    14701 tctgaggacc tttgggaaac tgttcgtgaa gcaggtatgg atagcgatgc taagactgtt
    14761 ctttatgatg gccgtactgg tgagccgttt gataatcgtg tgtcagttgg tgtcatgtat
    14821 atgattaagc ttcaccacat ggttgatgat aagcttcacg cgcgttctgt aggaccatac
    14881 tcactggtta cccaacagcc gcttggaggt aaagctcagt ttggtggcca acgttttggt
    14941 gagatggagg tatgggctct tgaggcttat ggtgcttcaa acgttcttca ggaaatcttg
    15001 acctataagt cagacgatgt gaatggtcgc ttgaaagctt atgaggcgat taccaaaggt
    15061 aagccaattc caaagcctgg tgtaccagaa tctttccgcg ttcttgtgaa agaattgcaa
    15121 tcacttggtc ttgatatgcg tgtccttgat gaagacgata atgaagttga gcttcgtgat
    15181 cttgatgaag gcgaagacga tgacgtgatg cacgttgacg atcttgaaaa agcgcgtgaa
    15241 aagcaggctc aggaaactca agatattgct gaatcaactg aagacaacta aatcataaac
    15301 atttgtaaca gaaataatga ctagactagg gctatttgcc ctagctgcta gtaagtcatc
    15361 aaaggcagaa aggtaaaact agtggttgac gtaaatcgtt ttaaaagtat gcaaatcaca
    15421 ttagcttcac caagtaaggt ccgttcatgg tcctatggtg aagttaaaaa acctgaaaca
    15481 atcaactacc gtacattaaa accagaacgt gagggtcttt ttgacgaagt catttttgga
    15541 ccaaccaagg attgggagtg tgcgtgtggc aaatataaac gtattcgcta taagggcatt
    15601 gtctgtgacc gttgtggggt cgaggtaacg cgtgcaaagg ttcgtcgtga acgcatggga
    15661 cacattgagc tgaaggcacc tgtctcacat atctggtatt ttaagggaat cccatctcgt
    15721 atgggcttga ctcttgatat gagtcctcgt gctcttgagg aggtaatcta ttttgcggct
    15781 tatgtggtta ttgatccaaa ggacacaccg cttgagccaa aatcactatt gacagagcgt
    15841 gaatatcgtg aaaaaatcca agaatatgga catggctcat tcattgctaa aatgggggca
    15901 gaggctattc aagacctcct aaagcgtgtt gatttggtca cagaaattgc tgagctaaag
    15961 gaagaattaa aaacagcaac aggccaaaag cgtatcaagg ctgttcgtcg gttagatgtg
    16021 cttgatgcct ttcataaatc aggcaataag ccagaatgga tgatcctgaa catcttgccg
    16081 gtcattccac cagatcttcg tcctatggtg caattggacg gtggccgctt tgcagcctca
    16141 gacttgaatg acctttaccg tcgtgtcatt aaccgtaata atcgtttagc acgtttgttg
    16201 gagcttaatg cgcctggtat cattgtgcaa aatgaaaagc gtatgctgca agaggcggtt
    16261 gatgctttga ttgataatgg tcgtcgtggt cgtcctatta caggacctgg tagtcgtccg
    16321 cttaaatcct tgagccacat gcttaaagga aaacaagggc gttttcgtca aaacctgctt
    16381 gggaagcgtg ttgacttctc aggtcgttca gttattgctg tgggtccaac gctaaaaatg
    16441 taccaatgtg gtgtaccacg tgagatggct attgagcttt tcaagccatt tgtgatacgt
    16501 gagattgttg cccgcgaatt tgccggcaac gtcaaagcag ctaagcgtat ggttgagcgt
    16561 ggcgatgagc gtatctggga tattctagaa gaggttatca aggagcatcc agtcctgctt
    16621 aaccgcgcac ctacccttca cagattaggg attcaggcct ttgagccggt gcttattgat
    16681 ggtaaggctc ttcgtcttca cccgcttgtg tgtgaggcct acaatgccga ctttgacgga
    16741 gaccaaatgg ctattcacgt gccgctttca gaggaagcac aggcagaggc tcgtttgttg
    16801 atgcttgctg ctgagcatat tcttaaccct aaggacggta agccagttgt aacaccttct
    16861 caggatatgg tgctaggaaa ctactaccta acaatggaag atgctggtcg tgaaggcgaa
    16921 ggtatggtct ttaaggacaa ggacgaagcg gtaatggctt accgtaatgg ctatgttcac
    16981 cttcatagtc gtgttggtat tgctgttgac agtatgccaa gcaagctttg gaaggatagt
    17041 caaagacaca aaatcatggt gacaacggtc ggtaagatct tgtttaatga catcatgcca
    17101 gaggaccttc cttacctcca agagccaaat aatgctaact tgacagaggg cactccagat
    17161 aaatatttct tgaagccagg tcagaatatt caggaggtta ttgatagctt accgatcaat
    17221 gtgcccttca agaagaaaaa tcttggtaac atcattgcgg aaaccttcaa gcgtttccgt
    17281 acaacagaaa catcggcctt tcttgaccgc ttgaaggacc ttggctacta tcattcaacc
    17341 cttgcgggct tgacggttgg gatcgctgat attccggtta ttgacaacaa ggctgagatc
    17401 atcgaggctg ctcaccatcg tgttgaggaa attaataagg ccttccgtcg aggcttgatg
    17461 actgatgatg atcgctatgt tgcagtcaca acaacatggc gcgaggcaaa agaagccctt
    17521 gagaagcgtc tgattgaaac acaggatcct aagaacccaa tcgttatgat gatggactca
    17581 ggagcgcgtg gtaacatctc taacttctcg cagcttgccg gtatgcgtgg cttgatggct
    17641 gctcctaatg gccgtattat ggagcttcct atcctgtcta acttccgcga aggcttgtct
    17701 gttttggaaa tgttcttctc aactcatggt gctcgtaagg gtatgactga tacggctctt
    17761 aagacagctg actcaggcta tctgacacgt cgtttagttg atgttgcgca agatgtcatc
    17821 attcgtgagg acgattgtgg tacagaccga ggccttctta ttcgagctat cacagatggc
    17881 aaggaagtca ctgaaacact tgaggagcgc ttgcagggtc gatacactcg taaatcagtc
    17941 aagcaccctg aaactggtga ggtattgatt ggtgctgacc aattaatcac tgaggacatg
    18001 gctcgcaaga ttgttgatgc tggtgttgaa gaggttacca ttcgctcagt atttacctgt
    18061 gctactcgtc atggagtgtg tcgtcactgt tacggtatca acctagcgac aggtgatgcg
    18121 gttgaggttg gtgaggctgt tggtactatc gctgcccaat ctattggtga gcctggtact
    18181 cagctgacca tgcgtacctt ccacacagga ggggttgcct ctaataccga tatcacacag
    18241 ggtcttcctc gtatccaaga aatctttgaa gcgcgcaacc ctaaagggga agcagttatc
    18301 acagaggtta aggggactgt tattgagatt gaagaggacg catcaactcg tactaagaag
    18361 gtctacgttc aaggtaaaac aggcatgggt gaatatgttg tgccatttac agcgcgtatg
    18421 aaggttgagg ttggtgatga ggtcaatcgt ggagctgccc ttacagaagg gtcaatccag
    18481 cctaagcacc tccttgaggt tcgtgatacc ttgtcagttg agacctactt gcttgctgag
    18541 gttcaaaagg tttaccgcag ccaaggggta gaaatcggag acaagcacgt tgaggttatg
    18601 gttcgtcaaa tgcttcgcaa ggtacgtgtc atggatccag gtgatacaga tcttctgcca
    18661 ggaaccttaa tggatattgc agactttaca gatgccaata aggagattgt tatctctgga
    18721 ggtattcctg cgacctctcg tccagtgctt atgggaatca caaaagcctc acttgagact
    18781 aactcattcc tatcagcagc ttccttccag gaaaccactc gcgtgctgac agacgctgct
    18841 atccgaggca aaaaagacca tctattgggg cttaaggaaa atgttatcat tggtaagatc
    18901 attccagcag gtactggtat ggttcgttac cgtaacattg aaccgcaagc tatcaatgag
    18961 gttgaggtta tcgaagaagc tgaagctaca gaagagccag caattattaa ggaataagaa
    19021 ataaaaggag ctagccttag ctccttttat catgctaaaa tcattagatt aattgggctc
    19081 catgtcaact atagtaggtg actgataact aagcacgaga ggagacgaag gtcgtcttct
    19141 cttttgtcat gttcaaagca agcatagata agtttcttga aattgtcaac gtttctgaat
    19201 ccaaatgcat tgcgcttgat gtctttgatc agtttgctag tcgcttcaaa cttggcgtta
    19261 gaataaggta gttcaatggc attagtgata tagtctttat attgtatgta gatagacaaa
    19321 actattttaa aaatgttaat caaaaataac ttaatagtgg aaaaatcgat aaattatttt
    19381 attataaaaa aagcttccaa aatttaattt tatcatttgt ttttttaaaa tatagtctta
    19441 tttttaagga aaatatatgt tattctgtac atgtaggttt cttaggtggt tcattttacc
    19501 agaaaggagt ttatttttag tagtaaaatt aactattacc ggtaaagatt gtttgtttta
    19561 attttagaga ttaaaaagga gtagattatg agactaaaaa aacttattta ttctagtatc
    19621 gctgcgcttg caattttaac ttacggtac
//
LOCUS       DARYLJ010000040        19484 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYLJ010000040 DARYLJ010000000
VERSION     DARYLJ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19484
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(220..1320)
                     /locus_tag="TU746_001452"
     CDS             complement(220..1320)
                     /locus_tag="TU746_001452"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL0891783.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1317..1673)
                     /locus_tag="TU746_001453"
     CDS             complement(1317..1673)
                     /locus_tag="TU746_001453"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL0891784.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TU746_001454"
     CDS             complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TU746_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL0891785.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TU746_001455"
     CDS             complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TU746_001455"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL0891786.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5753..6637)
                     /locus_tag="TU746_001456"
     CDS             complement(5753..6637)
                     /locus_tag="TU746_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0891787.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6994..10050)
                     /locus_tag="TU746_001457"
     CDS             complement(6994..10050)
                     /locus_tag="TU746_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL0891788.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEEHWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYDSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGLYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10279..12162)
                     /locus_tag="TU746_001458"
     CDS             complement(10279..12162)
                     /locus_tag="TU746_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL0891789.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12439..13878
                     /locus_tag="TU746_001459"
     CDS             12439..13878
                     /locus_tag="TU746_001459"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL0891790.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13883..14848
                     /locus_tag="TU746_001460"
     CDS             13883..14848
                     /locus_tag="TU746_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0891791.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
     gene            complement(15225..15730)
                     /locus_tag="TU746_001461"
                     /pseudo
     CDS             complement(15225..15730)
                     /locus_tag="TU746_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15727..17133)
                     /locus_tag="TU746_001462"
                     /pseudo
     CDS             complement(15727..17133)
                     /locus_tag="TU746_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17124..17483)
                     /locus_tag="TU746_001463"
                     /pseudo
     CDS             complement(17124..17483)
                     /locus_tag="TU746_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17495..17761)
                     /locus_tag="TU746_001464"
     CDS             complement(17495..17761)
                     /locus_tag="TU746_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0891792.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
     gene            complement(17960..18412)
                     /gene="nusB"
                     /locus_tag="TU746_001465"
     CDS             complement(17960..18412)
                     /gene="nusB"
                     /locus_tag="TU746_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL0891793.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
     gene            complement(18405..18794)
                     /locus_tag="TU746_001466"
     CDS             complement(18405..18794)
                     /locus_tag="TU746_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0891794.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            complement(18837..19394)
                     /gene="efp"
                     /locus_tag="TU746_001467"
     CDS             complement(18837..19394)
                     /gene="efp"
                     /locus_tag="TU746_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL0891795.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
BASE COUNT         5489 a         4798 c         3669 g         5528 t
ORIGIN      
        1 tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg ataaaggtaa
       61 gggccttttc ttattctttt tcttaacccg cagaaaaaca agacctgtct tgatctgctc
      121 tatctatgct gttagcctga ggtctcaaga cctttacagg actaatcatt tgaaagacag
      181 ccttgaggcc agtcaatagt tgagcctagg ctcaatttcc taatattctc taggaatacg
      241 atcactcagc aagcaaagca cctcataatt aatcgtacct ctataatcgg caacatcggt
      301 tgctgtgatt acttgtttac cctgctgtcc aatcaaggtc accttagtgc cgataggata
      361 ggctttaggc aaacgaatgg tcaattggtc catcgacaca cgaccaataa tgtcacaaaa
      421 ttccccttct accaatacct taaagccctg catatttcga gtccaaccgt cagcatagcc
      481 gataggtaag gtcccgacat actctggttc tgctgctaca tagctagctc catagccaac
      541 gctatcccct gcctgaattt gcttcacatg aaccaaacgt gattctaagg acaaggcttc
      601 ctttaaggga caaggtagac tcaagctatt gccgcttgga ttgagtccat agataacaat
      661 accaaggcga atggcattaa aaattgtttc actatgccaa aggcttgttg cagagttgct
      721 tgcatgcact aatgcaggcc tcttatctag ctgctccacc aactgcttga aaaaggtcag
      781 ctgcttatcg aacatggcat ggtcagagtc atctgcggtt gcaaaatgcg tgaaaatccc
      841 gtcaagctgc actcccatat cggataagat tgagatgagc tgattggcct cagcaagcga
      901 cctgacacca atgcgcccca ttcccgagtc aaccttgaca tgcacatgaa gctgactgaa
      961 atcaaccgat tcctttttgg caagctctag ccactctaag ctggccactg ttatcgtcag
     1021 ctgatgctta atggctagct gcaattcact tgctaaaatc acccctaaaa taaggatttc
     1081 cttatcaatg cctgcctgac gtaattccaa ggcttcatca aggtttgata cgcaatagcc
     1141 atcaacctga tcctcaactg ccttggacac tgcaactgcc ccatgaccat aagcattggc
     1201 cttgacaaca gcatatgtcc ttaccttttt aggaatatgc tgatgaatat ggtcaatatt
     1261 tgctcgaata gcttctaagt caactctagc tactgttggt cgatgtaagc ttgaaatcat
     1321 gctaaatcct ccaaaataac acttgcttga acatagcccc cactatgtga aatactgata
     1381 aaggccttac cctgaaaggg agattttgta atgacgggac gccctttgct gtcattgata
     1441 atttcaatat cctgaaaggt tagctggcca atccctgtcc ccattgcctt tgaaaaggcc
     1501 tccttaccag cccagcggcc ggccagatag gtcatttttc ggtgatggga aaattgctca
     1561 aacagcgcta gctccttgtc cgtcaaaacc tttctagcaa atctagcatt tctcaaataa
     1621 accttttcaa tagctgaaat atcctgtaaa tctatcccat gtccaacaat catttgcctt
     1681 tattttacca gccttcactt taatttaggg aaacaaatcc taaacaagga gaagccgaga
     1741 acaaatctca gctcctcaca ggttttcaac atggccatca cgctatcctt aaaaagcctt
     1801 acgaccatga cagtttttaa acttcttacc agagtgacaa ggacaagcat cattgcgctc
     1861 gactcttgaa aaatcagctg atgaatcaaa atcagcaccg atagcctgcg actgaatgtt
     1921 ttgtgctgca gttgttgttg catactgaat tgcacgctcg cgctcctgct catgaatctg
     1981 tgccttcatc atggtacgtg taacatcaaa ttcgatagca ccaatcatat cctgaaacat
     2041 cttgaagcct tcactttgat attcaacaac tggattattt tgcgcataac cacgcaaacc
     2101 aaccgcatta cgaagctggt ctaaggcatc aatatgctct gtccatttgt tgtcaacaat
     2161 catcaaaatc agcaccttct ggaattctaa gatagcgtcc tgatcgcgca attttgataa
     2221 ctgcttatcg taaatctcaa gggcacgctg atagagcttg tctttgatct gatcgtcctt
     2281 gaggccacgc aattccttag caccgatggt ttcctctggg acaattgatg ttctcgcaaa
     2341 agtcacgatg gcgtcaatag cgtccttacg attggtacgt gagtgggcat caactgctcg
     2401 atcaatcgta cgcttgatca ttgccttaat ttcaggacct aggtcacgat ttgctgtgat
     2461 aacatcacga cggttagcgt aaataatctc acgctgctca cgcatcacat catcatactg
     2521 caagacctgc ttacgtgtgt catagttatt accctcaaca cgtttttgag ctgactccac
     2581 ctggcgtgac agcattctgg acttgataac aatatcctcg tcatcattgt tcatacgatc
     2641 caagaaagcc ttaatacggt ctgtaccaaa gcgcctcatc agctcgtcct ctaaggagag
     2701 gtagaattgt gactcccctg gatctccctg acgacctgaa cgcccacgaa gctgattatc
     2761 aatacggcgg ctctcatgac gctctgtccc gataacacaa agcccaccga gctctcggac
     2821 accctcaccg agcttaatgt ctgtcccacg accagccata ttggtcgcaa tcgttaccgc
     2881 accacgctga ccagcattca taataatctg tgcttcttta aagtggttct tagcatttaa
     2941 gacctcatgc ggaatgcctg cttctactag ctttttagaa atcaggtcac tggtctcaac
     3001 agcaactgta ccaactagaa cgggctgccc cttttcatag cgagccttaa catctgcaac
     3061 cactgccttg aattttgaat tcaacgttgc ataaagaagg tctgtgtgat caatacgagc
     3121 aataggacgg ttggttggaa tcggaataat acgcatgttg taaacttcgc ggaattcctc
     3181 ttcctccgtt tttgctgtac cagtcatacc cgccaatttc ttatacatac ggaacatgtt
     3241 ttggtaggta atagaggcac ttgtttttga ttcctcttga atacgaacgc cctcttttgc
     3301 ctcaatagct tggtgtaagc catccgaaaa gcgtcgtccc tccattgtac gacctgtaaa
     3361 ctggtctaca atcaaaatct cgccttcctc gctaaccaca taatcaatat ccaaaagcat
     3421 gatataatta gcacgaaggg cattatccac gaagtgggtc aaggcaacat tttcaatatc
     3481 gtataggttg ctgaggttga aatagctttc tgccttatca atacctgagt cgcttaggcc
     3541 aatcgtcttg gtcggaacat caatgatgta atccactgaa tccaaggtct tgacaaacat
     3601 gtctgcacga atatagagct gattcgtttc tgagctcaca gcaccagata caatcagagg
     3661 tgttcttgcc tcgtcaatca aaacagagtc aacctcatcg accaaggcaa agttcagtgg
     3721 tcgctgaacc atgtcctctt gacgaaccac catattatca cgcaggtagt caaagcctac
     3781 ctcagagttg gttgagtagg taatatcaca tagataagcc tcacgctttt cagctggtga
     3841 tttggctgct aggttgatac cgactgaaag ccctagccag ctatacacct ctcccatctc
     3901 tgtcgcgtca cgagttgaca agtattcatt aacagtgata acgtgtaccc cttcgccagc
     3961 aagggcatta aggtaaacag gcatggtcgc tgtaagggtc ttaccttcac cggtacgcat
     4021 ctcagggaca tctccattgt gcaagacaac cccccccatg atctgaacac gataagggta
     4081 aagtcccagc acacgtctag ccgcctcgcg gacaaccgca aatgcttctg gtaataactg
     4141 ctcaagggtt tccccatttt gataacgttg tttaaattcg ggcgtttttg cttgtaggtc
     4201 tttatctgac aaggactcca tatagtcagc ataggactct acttttttcg caattttttc
     4261 taattttcgt aattcgcctt tatcattttc aatgactttg cgtagaatat tgctcattct
     4321 ctttcctttc gatcgactaa tcattttatt ctaacataaa taggcaggca gttcaagaaa
     4381 tgatcataag atatccatga cagacgcatg aagaaaatca tttattgaaa aagttgtgaa
     4441 aatagcaaaa tagccatttt agggtatttg acagagtgtt tcctgaattg ttatattctc
     4501 cctctataaa cttttcttga aaaatttctt ttctgcaact atcgctatgg ctttcctatt
     4561 tttcagaata agttttcgca ttcagaaata tcttggaaat tttttcttca tgcgtctgtc
     4621 gtgataagat atcagaaaaa gaaaggccgc ttgtccaaac agtctttctt ggtgttttcg
     4681 tgtattctgt acttaattag gatgactgac aatcatttcc agctgaccat caaagctcca
     4741 tgacgtcaca tcatttggca ggataaaatg catacccttt tgaagctcgt aaacagcttg
     4801 atcaatcgta aggcttccct gaccagctag cacactgaca agcaggtaag gggctgattg
     4861 cttcatgctg actgcttgat caatctccca tttgtaaact gtaaagaagg gattagatac
     4921 taagcaggta gagaccaagt gctcaagttc tagtgtggct ggcgtgctgt tctcaggctt
     4981 gccaatagtt aggacatcga tagatttctc aatatggagc tcacgaagct gaccttcagc
     5041 gtctcgacga tcaaaatcat aaacgcgata ggtcgtgtct gaggattgct gcgtctctaa
     5101 gatcaaaatt cccttaccaa tggcatgcat cgtgccgctt ggaacataga agaaatcacc
     5161 agccttaacc ggaactcgcg tcaacaactc ttcccagttc cccgcctcaa tcatcgcacg
     5221 aagctcttgt ttagagcttg catgatgacc ataaacaatc tcagcgcctt cttcagctga
     5281 aataatatac cagcattccg tctttcctag ctctccctca tgggccagcc cataagcatc
     5341 atctgggtgt acctgaacgc ttagccagtc attagcatct aaaatcttcg tcaacagcgg
     5401 aaagaccttt tcctttggat ttccaaatag ctctggtctt tctgcataaa gctgatctag
     5461 cctttggcct tggtagctac cactgctaac tgtggaaaca ccattagggt gagctgagat
     5521 tgcccaatac tccccagtgg tttcggttgg aagctcatac ccaaacacct ctcttagctt
     5581 tgttccgccc cagatcttat catgcatgca tgatgttaaa aataatggtt ctgacatagt
     5641 aatcctcatt ctcttttcac taacctatgg tgacattctt tgccccaatt ctaccaattt
     5701 caggcacatt ttgcaaatga ctctaggact tttatcaaat aggctcaagt atctagctct
     5761 tttcagcaat cagctttgct aaagcaaaat tcccaagagt ggccgagcca ttacctgcaa
     5821 ctgctggtgt gaccaaatat tctctaacat cagctactgg taaataacca ttaatcagtc
     5881 tggtaaaggc ctcctgaaca cgcaccagca tgtgctcctg tgccatcaca cctccaccaa
     5941 acacaataac ctgaggacga taaagcagcg ttgcctgtac agcagcctga gctatataga
     6001 aggcttgaat atcccaaaca gcggccttct gatcaagaag ctccccctta atccctgccc
     6061 ttgcttcaag gcttggccct gctgccatgc cctctaagca cccccgatga aatggacaaa
     6121 cacccaaaaa tgcattcgcc acatcgtcaa ggtgctgcat aacataggta tgtcccgcct
     6181 ctgtatgacc taacccaccg ataaactcac ctttttgaat agctccagca ccaatacctg
     6241 ttccaatcgt ataataaaca agactgtcaa catcaggtcg agagatagcc tccccatagg
     6301 cagaactatt aacatcagtc gtcacataaa aaggaatcgc aaaggctgct gtcagctgcc
     6361 ctaatagatc tacatttgcc caacctggct tgggtgttgt ggtaatgtag ccataggtag
     6421 ctgacttagg atcaatatca atcggtccaa aggagccaat agcaatacta gccaagtcgg
     6481 cctcaaattg cttaaaataa gcaatcgtac gctcaatagt ctcttttgga cttgtcgttg
     6541 gaaattgcac cttatccaca acagcaaaat ccctatcacc aacagcacag acaaactttg
     6601 tcccgcctgc ttcaatactt ccaagtaatg ttttcatctt ttctccttaa taatagtgat
     6661 aagccctgtg ctggttattc tcacaaggct caaaatccca ccagctaatc agcagctacc
     6721 ttagtagcta aacatcatcg cttgcttcct tgcctcctag aaaagaccaa aaatctggga
     6781 taggactatc tcagattttt gatatgcctt taagagataa ggcaattgat tttaggaggg
     6841 aaaccttggc agcaggagct gccaccaaga agcagcacaa acaattgctt ttaatggtgt
     6901 gttcatcgcc ttatctctaa agcttaatgt gttagcgtaa tgatcagtaa cctcaagcta
     6961 acggccaaga acgacagcct gctcaaggat aagctagtct gtctttggat tttctggctc
     7021 agtattttct tttatgtcag tagccacagg ctgctcaact ttagctgctt tagctacttt
     7081 ttcctgatca gttctatcag ctaaaagctt atcaacataa gccttcagat cagcagtact
     7141 agcgttaata gcatcggcat taaacatctt actatctaaa gcagccttta aggcagctat
     7201 tttgacttcg agctccttaa gctgctcttg agagaacttg tctttttgct gagatagctc
     7261 ctctgcagta gctagcattg ccatcacaag atccgcagcc ggtaattgat aaccaatgat
     7321 ttgaagctca ggaagtgatg gccaattgta aagtcctccc ttagtatcaa ctgttattct
     7381 ccaatatttg gcaccaatgt tgtttaacgg ctggctaaac tcttggtcct ctcctgaata
     7441 atctgaaact gttacccatt ttgatgattt ttccaagcta tcctttacct ttgagccagc
     7501 ttcaagatgg ccaacaaagg cttcaagctt ggcctcctta atacagtcag ctttactaat
     7561 tttgctgtca ttaaagaaac gccaatactt gactaagcca ggctctttaa gttcaaaaat
     7621 gatagaagct ttattgctag ttgacagaat tgttgtatca ttattgagca aaccatcaaa
     7681 cacttttttt gcatttgttg gatctgcatc accaccaatc acagttgctc cctctgctag
     7741 gttaaccatc atggtttttt ccgcaccaac gacaacctta gcctcatgca caggcttagt
     7801 gctattagta gggctaaaga attcaacctt gtaggtctcc tccttgctag tggataagtc
     7861 cttgtgatca gtgacaccta aggttgagtc agtcaccttg atcttatagt ccttgtaggt
     7921 cactgcaaag gctttgtaat catagcttga atcaacaaaa cggtgacctg ctatttcctg
     7981 ctcctgataa gccttatagt cagcttcgct attgattagc gtgccctgat tggtaactgt
     8041 tccaaataaa agcttagcct gcaaatcaat tgtatcattt gctactggta actgaaggct
     8101 cttagtgcca taagtatcag gataaagacc agtaggcttt tgatgatcaa atacaaacgt
     8161 cttttcgcta acaccgccat gcttagtcac tgttgccagc atggtatcaa gaatctgacg
     8221 attttccgta ccagctgcta agtccagctt attactagag agatccacct tttcaagaga
     8281 ggttaggcta gctgcgtcaa ttccagccaa gctatcacga tcaaagccag caagatttaa
     8341 ttccttcaag ccagttagac cagaaatggt cagagccacc tgtggaatcg ccttagtctc
     8401 ttccttctta gcgctgtcgt aggcttcaag aacattggcc agcgtatcct tggtcggctt
     8461 agcatttgca ggtaggacta agctatccag ctttgtgatt tgtgatagac cgattagctc
     8521 tagcttagct agttttttaa gcttattcag gccttctaaa ctcttgatat ccggattgtc
     8581 taagcgcagg gttccattga accgctctaa atcccctctt ctgcttccaa cctgtgcaat
     8641 aactgcttct cgcaaagcct tgtctggaaa atctttctga tcaatcagct cataggattt
     8701 gtcattttcc ataaccttct tcaaggcctt agaaacctta taatctgatt tgacaatacc
     8761 atctgttata tcctttatag ccttgttagt tcttttctca tcatctgaga cttttttagg
     8821 ttgatgcgct acaccatcgc gatcaatcgc ataagagaaa atccctccct tgacaccacc
     8881 tgtcttaggc tgccattttg cataacgctc agcacgagta ccagctatct ctgaatttaa
     8941 cggattatga tcatctttcc tctcattaat atcataccag aggttaccac tgcccgcatt
     9001 ttcctcatag aaagaaaaac caaccatgta ctgctcagga cgaatgtatt tgctatacga
     9061 ttcccaatgt tcctccattg tcttttcagg ttttctagcg actggatccc aatctccctt
     9121 ctcaccttga gtgccataaa cctgcacaag cagcaaatca atatattggg caccgcgctc
     9181 aatcaatggg ttcttgtcag ccatgtaggt gctatccata atgaacaaac gtgacttgtc
     9241 agcgcccttt ggcccaataa gcttgccaat ttcttcaaaa acagcaatag agcgctgaat
     9301 attttcgtta ctctcttttc catttacttt tggaatgcta tcccgctcaa tatcaacatc
     9361 taaaccatca agattatatt tataaacgta ttcatctaca atagcctttg ccaaggcctt
     9421 atttccctct ggagtatttg ggtatttttg cgtatcttca gcaataccac tatgatcacc
     9481 gcctgcaagg aaccgccatg gaatggtacg aatcacacgt gttccctgct tgttcagcgt
     9541 tggcacatgc ttggtcgcca attcttgcca gaaaaagcta taatccttgg tccaatcatg
     9601 gaaaacaaag gctaagtcaa cctccttagg caattctccc atagaattaa ccttatcctt
     9661 ttcagccgga tctgatgttt tatcatgcca agtcctaaaa tagccaccat aaagaggccc
     9721 ctttaaaggc ttcatggcta ttttttcagg aaccttcatt tctgcaagaa cctttgcctg
     9781 cttatctgcc tgctgtgcct tggataaaat atcctttagc ttttcaggta cttctcctgc
     9841 ctttgataac ccctccttaa attctttttt actgttttcc gacaggtaat gtaggtcatc
     9901 aatagcagag actgatggac tagtttgcac aaccttatcc tctgccttga cccttatgag
     9961 tgaatcatgt tgggcagcta atatagccac cattaacgct gcagcacaaa cacatttcag
    10021 tgttttcttg actaacacct gtttttccat tgggacactc ctttattttg ataccaaaga
    10081 atggcaaatc tttgctgaac caaaaatgta agcgcattct ctgcgttcgt ctaaagtata
    10141 gtagacctca tgatcaaaag caatgcacaa agtataggta aaataaaaga aacttaaggt
    10201 cttttaattt ctgtaatttt atggtgaata ttttaatctt acatgtaaaa agagatgaaa
    10261 tcatcaactc ttttcaaatt attttacaag gatcactgga ctgccaacag tcaccttacc
    10321 ttgtgccaaa atctgaacag catgaacatc tgcgctattg gtgacaagca gcatggttgt
    10381 agtatcaagg cccgcctgct gaatccttgc aatatcaaag cttccaagag catcaccagc
    10441 cttgaccatc tgaccaacct taacaaaggt ttcaaagccc tcacctgcca ttgaaacggt
    10501 atcaatacca atatgcagta ggatttctgc tcccttatct gatttgatga cgtaagcatg
    10561 acctgtctca agggcagcct ctaccctgcc atctaccggt gagcagagaa tgcgcccttc
    10621 aggcttgatg gcaacgcctt ggcccatgct tcctgacgaa aagacaggat cagcaaccga
    10681 tgacaaatca atcaactccc ctgcaactgg actaagcagc tcctcagcag cagaggcttt
    10741 ttgcgcaggc tctgatttta cttgggtagc cggtgcttct tggtcactct tgtccttgaa
    10801 tccccaaata taggcaatca caaaagctag accaagccca accaacagtg tcacaaggta
    10861 ctgtagtagc tgaccattaa gatacagcag tgcaccaggc aaaaccgtaa tcccaaagcc
    10921 ggtaccagca atgccaagaa tccctgcaac ccagccacca gctgcgcccc cgataagtcc
    10981 tgagacaaat acctttgggt agcggagatt aaccccaaag atagccggct cagtaatccc
    11041 taaaagagct gacagagctg atggaaaggc taaacccttt aattttgcag acttggtttt
    11101 aacagcaacc gctagagttg ctcctgcttg ggcggccgta gcagctgtca aataagcgtt
    11161 aaagggatcc tttcctgtat tggcaactag ctgcgcctcc aagaaattga aaatatgatg
    11221 gatacctgtc acaacaatca gctgctgaac acccccaata acaaggccgg caatcccaaa
    11281 aggcagacct aaaactgctt gtgtccctgc aagaacaagg ttttccaagg agtgaaagat
    11341 aggcccaatc acaaagagcc ccaaggcact cataatagca aaggtcaaaa acggcgttgc
    11401 caacaaatca agcgcatcag gcacccgctt atgcagccac ttttccagct tggcaccaac
    11461 cagaccaaca aagaaggctg gcaataccgt accttgataa ccaacaactg gaacaaaacc
    11521 aaagaaagtt aagggcttaa catcacctcc tgaggctacc acccaagcat ttggcaactc
    11581 attagagacg agcatcaagc caaggacaat cccaatgata gggttgccac caaataccct
    11641 aaaggctgac caagcaacca aggccggcag gtagacaaag gccgtatctg ttaaaatccg
    11701 agtgtacatg aggaaattgt cgccatagtc atgaatacca aagaactcca taacagccgg
    11761 ctgcgtcaag agaccccgta cacccataaa cagccctatc gccacaatag caggaatgat
    11821 cggaacaaag acatcaccaa aggtacgaat agcccgctga aaggcatttc cagacttgac
    11881 cacttgctcc ttttgctcac ctgccaaagc agctggaagc cctagagcta caacctcatc
    11941 ataaatgcta ttaaccgtac ctgtcccaaa aatcagctga tattggcctg agttgaaaaa
    12001 agcaccctta accttatcaa tagcctctgc tttttcctta ttgatcttac cctcgtcatg
    12061 aaccataacc cgcagccgcg tcgcacaatg agccacactt ctgacatttt cacgaccgcc
    12121 taaggcctcg ataacctctt ttgcaatctg atgattatcc ataccgatag catctccttt
    12181 tttgtctgtt atagtctatc gaaatagctt ttcttgagcc tatccaatat tggcggacct
    12241 accctactgt ccgactcaag atggtctttc aatttactat tgtgaatccg cttcacttct
    12301 tgctatcatt ttaacacgaa tattttttat gtcaagcgtt tgacatatat tttgtttaaa
    12361 ataattaaaa aagttgattt ttagagagaa aacgtttatc atatgaataa aaatgaccaa
    12421 tacctaagga gacctgacat ggatttacca agatctattc gctaccgacc atatcaagaa
    12481 tggagcaagg aagcctatca agcaatccaa caaaaggtgg cccagtcttt atggcgcagc
    12541 catttccata tagaagctcg tacaggtctc ctcaatgacc caaatggctt ttcttatttt
    12601 gctggcagct ttcagctttt ctatcaaaat tggccctttg gagcagctca tggtctaaag
    12661 caatgggtac acaccacatc aactgacttg gtgcatttta cagaaaccaa aactcggttg
    12721 ctgccggatc atcaaaacga tagtcatggc gcttattccg gctctgctta tcctattggt
    12781 gacaaactct ttttatgcta tacaggaaat gtccgcagca aggattgggt acgccaccca
    12841 ctacaaatag gtgcctggat ggaccaatca ggccacatca caaaatgtga gcaggtgctc
    12901 attgacaagc cagatgatgt cacagagcat tttcgtgacc cccagctctt tacctaccaa
    12961 gatcagcttt atgccatcat tggtgcacag aatttgcaac aacaaggtat cattaagctc
    13021 tacaaggcta acaacaatga tgtcaccagc tggcaatttg ttgctgactt ggattttgat
    13081 gactcaggca ccgcatacat gattgaatgc cctaatttgg ttttcattga agataagcct
    13141 gtgcttatct tctgccctca ggggcttgcc aaatcagagc ttgattacca aaacatttat
    13201 cccaatacct ataaggtatt tcagaccttt gatcctaaaa gacgcaagct ccttggggga
    13261 ggtccaatcc aaaaccttga ttttggattt gaagcttatg cgacacaggc ctttaatagc
    13321 cctgatggta gggtactggc agtttcttgg attggcctgc cggacatcga ctacccaacc
    13381 gataaatatg cctaccaggg agcgcttagt ctagtcaagg aattacgact caaaaatgga
    13441 aggctacacc aagcaccagt ccctgctctc agtaagctac gagacaaagc ccagcccttt
    13501 cagaacaaaa aaaacagctc aaactgctat gagctggctt tgaccattga agcacagcaa
    13561 gcaacagagc ttttgctctt tgccgataca cagcacaagg ggctgaaact gaccgttgac
    13621 acctgcaaag gacagctaac aattgatcgc agcaaggcag gcgcccagta tgcccaggaa
    13681 tttggagcaa agcggtcttg ccaaattcct gtcaatcgtg ctacacttaa tatctacgta
    13741 gacaagtcta ttctagagat ttttgtcaac caaggcgaag cagtcctcac gagtcgtgtc
    13801 tttccaaatg aggggcagtc tggcattgag ctgctaaagg gccaggtgag tggctactat
    13861 tatgaaatga ggtactagac aagtggtcgc aaaattaaca gatgttgcag cattagctgg
    13921 tgttagccca acaacagtct cacgtgtgat taacaaaaaa ggctatctgt cccagaaaac
    13981 cattgataag gtgaacaaag ccatgcgaga gcttggctac aagccaaata acctcgcacg
    14041 aagcctgcag ggcaaatccc ctcagctcat tgggctgatc tttcctaaca ttagtaatat
    14101 tttttacgcg gaattgattg agcatttaga aatcgagctc tttaagcaag gttataaagc
    14161 catcatttgc aacagtgaaa acaacccgat caaagaacga gattatttag aaatgctagc
    14221 tgccaatcag gttgacggca ttatctcatc aagccataac ctaggtattg atgattatga
    14281 gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc gctcctcata tccccatcat
    14341 atcctctgat aattttgaag gagggaaatt ggccgcaaaa accctgcaaa agcatggctg
    14401 ccaaaaaatg atcatgatta caggaaatga tcattctgac tccccaacag gtcttagaca
    14461 gctaggcttt aattaccagc tcaaaaaagg cgctgatatt ataaaactgc caaatgatct
    14521 ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg gcgacaagaa ggcctgacgg
    14581 catttttgct tctgatgatt tgacagctat cctcatcatg aaggttgctg gccagcttgg
    14641 catagcaatt ccagataacc tgaagcttat cggctatgac ggtacggctt ttattgagca
    14701 ttatttccca cagctcacca ccatcaagca gccgatcaag gagattgcca gcttaaccgt
    14761 agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc aaggactatg tcttaccgat
    14821 caccctgctt cccggaggca gtctctaaga gcaatagctc ttcttctgtg attagcggct
    14881 ttcccctagc ttctccctta cttggggcac taaagtaaaa accaaagcac gaggtgggaa
    14941 accctagacc accaggatac acccagatag gtccccaaaa gaaagcttga taagcctgac
    15001 cacctaacaa aacctgcaca caaggaaagc ttcctcaagc tgtcctttgt acccttttcc
    15061 taacaatgcc accaaaaaca catgtaacag caagtgacag actcccccta tagcaaacag
    15121 tgacccaaca aaccatcact agaagctata aggggagctt ttctatgcct aacaaaaatc
    15181 taaaatcaat aacagaaaaa cctaaagcag ttcatgcgca catactacct atctgctact
    15241 attgctctaa aagcaaccgg ctgatcggac aggttggtaa tggtgatact atagtcatga
    15301 tcttctgtca cactatattt tctcttcccc ttcaagggaa cgatgaggcc atctccatca
    15361 atagtagctc ccttgtgtcc agcttctaca ataactacac cattatcctt agtggaatcg
    15421 tatttttcaa taacctgttc tgttatagaa taccgatatc ctatcttact aagatagctg
    15481 tctgtccgtc tataaatata ttcagaccat atatcacgac cttctagctt cagtagcact
    15541 ttttcgtcgc tttctaggta taggtcagag gaatattcta tttgttcata ctttggtctc
    15601 accgcaagct ctatactctc atttggcctt agatattctt ttccttgaaa aaatagtaaa
    15661 gctcatagcg tttggagaag atgaaaacac ctaccagcaa catcattaat aacaggattt
    15721 ttcgcttcat tttgacttct tccttttcat ataaccatct atacctgctt ggatcatttg
    15781 agtatcaccc tcattgtctc catagtgacc tgatgataag ttctttaacc actttggtat
    15841 atccttatca gaaaagacct gggcaatctc agccgccgtt tttaaataag tccctgaagc
    15901 atctaaaaag cctgtaccaa cataaccata gaggtagttg ccagcatagt cgcctggcaa
    15961 ttctgattcc cactgtcttg accagacaga atagttatgg ccatgatagg tccttgactt
    16021 caaatccaag ggctgacccg tattgacaag gtcataaaat tgtttgttgt caagtattgc
    16081 agcacttaat tgacttccag ctacctgtga aaggtaggga gcattgacat tcactgatag
    16141 gatatcatct cccatcttgt tgacaatcaa acgaaaatta atacccgacg attgtaattt
    16201 tttccctagg tcttcctcaa tttcctttgc atatttatta tttttaaggt ctcactctcc
    16261 atcataattg cttctcgcct tccaatagtc atcaaaggct gttttattga gaaaatagag
    16321 gtaatcctca taggcagcta caagtcgctc tgatttttgt agtggccttt cagagctgct
    16381 tttgatggtt ttaatggtct gagtcagtat gttgtgataa tggttttgag tgtactttga
    16441 ggcattgaca gggctaatct tttgattctt caggctagtc acccagctca tatctaggcc
    16501 agcagtcgag tagctgccgt cgctgctcat gaagacctga ctgagctgtg ttgcgccctg
    16561 aatggctaac cgcaaaataa ctaagctgtc cctaaagcag tctgaggttt gagttagaaa
    16621 ccattcaagg ctttccaatt tggtcgtaac atctcgaatc cctatttcca gctggttttt
    16681 ggcatggtat agtgtagagg tatcagacca aagggtgcca tagtctccgg ttaaaagact
    16741 actgacctgc ttcataaacg attcgttttc atcaatctgt gcttggatca cttgcacttg
    16801 ccgttctctt agcctcttca gctcggttaa gtgatcacga tccagggttc cgtatctggc
    16861 aatctgagca tctgcccttt gataggtggt caactccact tggatagcat caatcgctgc
    16921 ttgtagcttt ttgatagagg gaatgatgat cgctgtaaaa agtcccctac ctgctgtata
    16981 ggctgctccc tgtagctctc ccgaatccag actagcaatg agatggtcgc aaccacttga
    17041 taacctgtcc gttatttcat tggctatttg gatattgttt gtcatggctt gaatcaaggc
    17101 ctttgactct gctgcactgt aggtcactcc catcgtaaac ggctcctttc accgataagc
    17161 tcttctttgt ccctctctag tctacgacga acccccatcg tatagattga cacgtgatcc
    17221 agatgctcat caacatagcg atccatttgt ctgatcaagt ggtcattggc ctcttgctct
    17281 gcgtactttc cagcttagtc ctcaggcata tggttcaata gggactcaag ggcaaaagag
    17341 aggtgctgac agtctgcttg aatctccgag actgcttgtt catgccgtcg tttcatcgac
    17401 aaaagatcct cctctagcca ctccagctca ttgatctgtc gggttagggc aagaaatttt
    17461 tcttcagatt cttctttgat catgacttat tcccctatct tgttgcttcc tctaggtctc
    17521 ttttctctaa tttggccgca agctgaggaa atttattagc ctgaataagg actgcctgac
    17581 taaagtcgct gacagcctgc agcagttgat tagagacctg acgtcccttt tccatacctg
    17641 caataccctt ggtcacacta aatgcaacgg actgttggtg aaccctactg gtgtctacac
    17701 ctaccaattc actaatagca gcagaagcag ccacagggct tgatgtaatg gtatcactca
    17761 tacaatttct cctttataac ccttatgtct tttattatat cacaggataa tagccattgt
    17821 gcttatagct cttacctaaa taatagcaac tgatgaatct ttttgggaat tcattgacat
    17881 agccaaccag atgagacgtt tttgagcatt caaaaagccc tatagggctt tagtaactta
    17941 agaagctttc accagcttgt tattctgtca ctgcagctga ctcatcagaa acaaactgac
    18001 tgagtaagcc attaataaac ttagctgagg tatcatcaga atatttttta gcaatttcaa
    18061 tgatttcatt taaggctaca cgatcaggtg tctcctcaaa cagggtcatc tcaaagagcc
    18121 caagacgcaa catcgtcttg tctaccactg tcaagcgctc aatggaccag ctcgttttaa
    18181 ggtttttctt gataacctca tcaagctcag ccttatgatc cataacgcca ttgacaagat
    18241 ttaacagaaa aacaggaagc tcagaaggct gcttgtcatc agctgcttcc ttgtcatagt
    18301 cataggcaaa ctgtgaggca ggcagaaaat ctccgcccat ctccatagca aataaagctt
    18361 gaaaagcacg ctcacgcaaa tctcttctcg aatgttgaaa atgcttagtc atccaaaaaa
    18421 tcctcatcaa acaatgattt catttctggc tttggtgtct tttcaggaac aatcccctca
    18481 acatggatat taacataaga aatggtaacc tcagccatgt cataaacagc tgacttaaca
    18541 gccctttgaa tagccattga caccgcagga acctttacac catattgcag gtaaacatag
    18601 atgtctgcat tgactgttcc attttcttcc gtctgaagat agacgccctt accaagacta
    18661 gctttattaa aggtatctgc catgttttta ttgtgaagcg agtgaacacc ctcgacctgc
    18721 atcgtagcaa ttcccgtaat aacctcaaga actcgtggcg aaataacaat ttcaccgata
    18781 ttttcagttg tcatagcatt tcctttcttt ctcttagact aattccggaa agcgaattaa
    18841 gcgcgagaaa cgtaagtccc ctcagcagta ttgatgatta gcttttgtcc tacctcaata
    18901 aagtctggaa cgtttaccac gagtcctgtt tcaagggttg caggcttacc agagcctgta
    18961 acagttgctc ccttgattga tggctgggtc tctgtaacag tcaactcaac agtagtcggt
    19021 acctgaactc cgatcacctc tgttccataa aactggattt tcacatcaga gttttcaagg
    19081 atatataata gctcttgctc aacattggct actggaatct catactggtc ataggtttca
    19141 gtattcataa agtaagcagt ctcgtccatc ttgtaaaggt attgagccgg cactgtttcg
    19201 ataatagcct gttcaaactt ttcgtctgga cgataggttg tgtcgaatgt agagccagta
    19261 cgaacatcac gcaatttcat acgcatgata gtgtttccct tacctggctt atgatggctt
    19321 gcttcaagta cgcgaattag ctttccttct gcttcaaacg tcatacctgc tctaagcttg
    19381 cttgcttcaa tcatttgtta ttacctctta ctaaaatagt tatcgtctta ttttaccaca
    19441 aaagagctgt aggctcaaat gttttatgac cattatcagc cctt
//
LOCUS       DARYLJ010000041        19343 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYLJ010000041 DARYLJ010000000
VERSION     DARYLJ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19343
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..1230
                     /locus_tag="TU746_001468"
     CDS             <1..1230
                     /locus_tag="TU746_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL0891796.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLD
                     KKQSNSFNIFRKAGFGL"
     gene            1242..2744
                     /locus_tag="TU746_001469"
     CDS             1242..2744
                     /locus_tag="TU746_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0891797.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2725..4302
                     /locus_tag="TU746_001470"
     CDS             2725..4302
                     /locus_tag="TU746_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL0891798.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4304..4510
                     /locus_tag="TU746_001471"
     CDS             4304..4510
                     /locus_tag="TU746_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891799.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4507..4926
                     /locus_tag="TU746_001472"
     CDS             4507..4926
                     /locus_tag="TU746_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0891800.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5123..5392
                     /locus_tag="TU746_001473"
     CDS             5123..5392
                     /locus_tag="TU746_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891801.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5428..5595
                     /locus_tag="TU746_001474"
     CDS             5428..5595
                     /locus_tag="TU746_001474"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891802.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5777..6400
                     /locus_tag="TU746_001475"
     CDS             5777..6400
                     /locus_tag="TU746_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL0891803.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6411..6791
                     /locus_tag="TU746_001476"
     CDS             6411..6791
                     /locus_tag="TU746_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL0891804.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6794..7843
                     /locus_tag="TU746_001477"
     CDS             6794..7843
                     /locus_tag="TU746_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL0891805.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7854..8120
                     /locus_tag="TU746_001478"
     CDS             7854..8120
                     /locus_tag="TU746_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891806.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8130..8483
                     /locus_tag="TU746_001479"
     CDS             8130..8483
                     /locus_tag="TU746_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0891807.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8480..8788
                     /locus_tag="TU746_001480"
     CDS             8480..8788
                     /locus_tag="TU746_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891808.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8769..9134
                     /locus_tag="TU746_001481"
     CDS             8769..9134
                     /locus_tag="TU746_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0891809.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9131..9520
                     /locus_tag="TU746_001482"
     CDS             9131..9520
                     /locus_tag="TU746_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL0891810.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9530..10121
                     /locus_tag="TU746_001483"
                     /pseudo
     CDS             9530..10121
                     /locus_tag="TU746_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10183..10542
                     /locus_tag="TU746_001484"
     CDS             10183..10542
                     /locus_tag="TU746_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL0891811.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10584..10913
                     /locus_tag="TU746_001485"
     CDS             10584..10913
                     /locus_tag="TU746_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891812.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10930..14184
                     /locus_tag="TU746_001486"
     CDS             10930..14184
                     /locus_tag="TU746_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL0891813.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14216..14995
                     /locus_tag="TU746_001487"
     CDS             14216..14995
                     /locus_tag="TU746_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL0891814.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14992..17049
                     /locus_tag="TU746_001488"
     CDS             14992..17049
                     /locus_tag="TU746_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0891815.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17049..17756
                     /locus_tag="TU746_001489"
     CDS             17049..17756
                     /locus_tag="TU746_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0891816.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17758..18372
                     /locus_tag="TU746_001490"
     CDS             17758..18372
                     /locus_tag="TU746_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891817.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            18383..>19343
                     /locus_tag="TU746_001491"
     CDS             18383..>19343
                     /locus_tag="TU746_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0891818.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQS"
BASE COUNT         6551 a         3379 c         4333 g         5080 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaaagataaa
     1081 aaaacaaatg agtatattaa cgacccagtc gatagttata accactgcat tgacgcgatt
     1141 aggtatgcga catctaatca tttcttgaca ctggacaaaa aacaatccaa tagctttaat
     1201 attttccgca aagcaggttt cggactctag aaaggagaac aatgttatac acagaaacgt
     1261 ttaaagacag cacaggtaat gctaaattac ttgagtttag attccatcgt gagtctcgta
     1321 tgaggtatca gacaagcgat ttaagcggcc tttttgacga agggtataaa ctattgcttg
     1381 actatatcaa acaccacgaa agcaagcaaa aaccacgcat acaggagctt ttagactatg
     1441 ctgagggtaa taatcataca gtctgcgaat caggccgcag acgagaggct gatatggcag
     1501 acagtcgtgc tatacacaac tacggtaagt atatctcgac ctttaagcag ggctatttag
     1561 ttggaaatcc tatccgcgtg gaatatgagg acaatgatga tgctaaaaaa caattgttca
     1621 aggagctggc ggataaaaat aacttccacc aacttaaccg tagacttgtc aaggatttat
     1681 ccaaggtagg ccgcgcctat gaacttatct atcgcagcat ggacgataag acagaggttg
     1741 tgcgattaga tccacgagaa acctttatta tctatcaagc tgatgttggg caagctagcc
     1801 ttgtgggtgt gaggtactat aacaagagtc agctggatag aacaaagaaa acagttgagg
     1861 tctacacaga taacgagatc atttactttg attatgatgg gcaactgaca gaggttgata
     1921 ggcggccaca catttttaaa tctgtaccta tcacagagta tctcaatacg gacgatggcc
     1981 ttggtgatta tgagacggag ttgtctttaa ttgacttgta tgatgcagct caatcagaca
     2041 cagcaaacta tatgcaagat ttgtcagatg caatcttggc tattattggt cgagtatcgt
     2101 tcccgagtta tgtagacacc aaggaaaaag ccattgaata tctgcgtgct atgcgcaaag
     2161 ctaggttgct aaatttagag ccaccagtgg ataccgaagg tagagaaggt tctgtagatg
     2221 ctaagtatct ctataagcaa tatgatgtca acggcacaga agcttataaa gatagggttg
     2281 tgcaagatat ccacagattt accaacacac cagatatgtc agatagcaaa tttgcaggca
     2341 cgcaatctgg agaggcactc aagtggaaag tctttgggct tgaccaagag cgtgtagact
     2401 tgcaagcact gtttgagcaa tctctaaaac gtagatataa gcttatcgca agagttagtg
     2461 agctgttaaa agaaattgac ggatttgaca ttagcaaact taaaattact tttaccccta
     2521 acttaccaaa atcgctacat gaaaaaattg aagcttttaa agcacttgga ggggagttgt
     2581 cgcaaaaaac aacaatgtct attacagata ttgtggaaaa tcctgataaa gagattgctt
     2641 ccatcaacga tgaggctaaa aatcgtagtt tattggcgca aaagatggag tcagaaggta
     2701 gaatgacgga tagggagtta gctcgtgact acaatcatga ataagagtaa atattggcgt
     2761 gatcgtgtta aaaaagaaat ggacgcaaaa gaggcagatg atatctccct tgaacagtcc
     2821 atgaaacaat tacacaatta tcattttaga aatatcgaaa aagaaattga gtcattttat
     2881 caacgttacg ctgataaaga gaaaatagac atcgcagaag cccgtaagag agtttctgag
     2941 cttgacattt ctgcttacca gaagaaagct aaggaacttg ttgtaaaggc tgagaagcta
     3001 cgaaaagagg gtaagacagt aacgagagat gactttaccc accaagaaaa tgcagacatg
     3061 gccatctaca atttagcgat gaaaactaac gctttagaat tgttgcgctt gaatatcgac
     3121 ttggagatgc aggagctcgc aaatggcgaa cataagctaa ccaagacatt tcttgacgaa
     3181 ggataccgca aagaggttga gttccaagcg ggattgttag gactgtcggt tgctagccaa
     3241 gcaagcgtga aagggttggc tgacgcagtt attaacgcta atttcaaagg cgcaaaatgg
     3301 tcggatagca tttgggacag acaagataaa ttacgcagca ttatatccca gagcgtacag
     3361 agtgctatct taaaaggtaa aaatggttta actattgcaa gggatattag acgagagttt
     3421 gatgtgtcag tgtcttatgc aaagcgaata gcaatcactg agcatgcaag ggtgcagatg
     3481 gaagttagta gattatccat ggcggagaat ggctttgcta tgtttgacat tatcccagag
     3541 cctaaagcat gtgatgtttg taaagacatt gctaaacaag gtccatatca catggataag
     3601 tggcgaacag gggaaaacac gccgcccatc catccttatt gcaggtgtgc agttgttgga
     3661 gtggaagaag aaaatagtag taatcatgaa tcacttgata agcttattaa aacagagtat
     3721 aatcaaagta tgaaagagtc atcgacttat gctcgtaacg ttttgtcggc agtgtcattg
     3781 atagagcctc gaattacatc gcaaattaag catattgtca agcaatccaa cggtaattta
     3841 caaggacttg attttagatt aaaaagtcta gattctttgg ccagaaagat ctctactgat
     3901 agcttgttgg acgatatttc accggaagaa gccgcaaaca acataaatga tgcattacgc
     3961 tatacagctg tatttaaacc ggataatttt tttgatgatt atcatagcat gaaaaatgca
     4021 ttggtcagag atggttttaa aatcgaaaag gtgaaaaata cttggctaga tgatggtcca
     4081 tataacggtg ttaatactgt tgtatcaaaa gacaatgtca agtttgaaat tcaatatcat
     4141 acccaagaaa gctttgattt aaaaaacggg aaactgcatg aattatatga ggagagaaga
     4201 cttcctaata taacacgaaa acggaaggct gaactagaca aaatgatgtt tgagcttagt
     4261 aaatctttaa ctaaacctaa ccaaatagaa agggtgaatt gatatgatta caaaatattt
     4321 ttttataaaa accgaacacc ccaaaattgt tagatattct aatgggttaa cagaagttta
     4381 taacagcgca aaaggctggg aagaacaaga agcttggtac gatcgtctat tctttagcga
     4441 tttcagtgat tttgaagagg ttacagaaaa agaagctaaa atgtttattg cgggattgac
     4501 agcggcatga gtattgtgga gctagctttc agagtggcta aaaaagccca ccttggacag
     4561 gttgataagg ccggtgtcga ctatattaag caccctataa ctgttgcaag ttttgtaaaa
     4621 actgatgaag aaaaggcaac ggcttatctt catgatgtta tcgaagatac aagtttgact
     4681 ttacttgact tggaagagta tgattttcct cgaagtgtta tagaggcagt tgatatactg
     4741 acaaagaaaa aaggacagga ttatcaatcc tatctaaacc ttgttaaaac aaataaactt
     4801 gcaagaactg taaaattagc tgatttaaaa cacaattctg atttatctcg tctctctgaa
     4861 gtaactaaca aagatttaaa acgctataaa aaatatcaag aagctatcaa atatttaaac
     4921 aattaaacaa caacagacgg gcaaccgtct ttttttgtac cccaaaaaca ggaggaaatg
     4981 atgttgaaaa tagtgaaatt tttgaaatat gtttggattt ataagtgtaa acctgtcagt
     5041 ccaagtcttt atgcatcgag tcggattgag tacttcaaac ctcttggtta ttactgggaa
     5101 aaagcaacga taggagaaag caatgaataa acgaatcaaa aagaaacgta aactagaaac
     5161 agtagtagtg atgctggttg cggaaaatgc cttgcaggct gaagcgctca taaatcaaaa
     5221 caaagaaatc atggagctaa aatcaatcgt tgagcgaaac gctctggcaa caaacgaaga
     5281 gttagcgact gttaaagaca ccgttttaga caaccaatca gttatcaagg caattggtga
     5341 cacggttgac tacatcaagc aaaattacaa acgtaagtgg gggaagaaat gaagtatctc
     5401 aagaaaaagt aatagtaagg agttattttg aaagtcaaag agatagcaca ggtgtttaat
     5461 gaatattcgg atttttttgt ggtacaaaac ggtaaatatc tacctggtga cagaactagt
     5521 ttttttctag attgcgaatt ggaaatcaaa gaaatatcta tcggaattcc tgattgctta
     5581 attattgaag tataaaaaat tcaaagtcgt agcaatacgg ctttttattg tgccctgagc
     5641 atggcctaaa aaggctcaaa ttaatcacta gcgtggcttg tggataaata cacctaatag
     5701 agactagaaa acatgaggcg cccgttttcg tggctctgca gtgtgtttaa aagcaagact
     5761 agcgtgggag gaaaaaatga ataaaaaact attagaaaaa ctttttaaat gtgctccaga
     5821 tactggcaca ggttcaggag gagcttctga tgcagatagc caacaatccg aaacagatgg
     5881 agaaccatct agtgaagaca gctttaaagc tccacagtcg caatcagagt tagatagcta
     5941 tacgaataaa gcaatccaaa aggcattgga aaatcaacgc aaagatgaag ctaaacgaat
     6001 agaagaagct gtaaaagctg ctttagataa agaaaaagac tactccaagc tatctgaaga
     6061 agaacgtcag cagcgtgaat ttgaagatag taagaaagcc tttgaagctg aaaaagccaa
     6121 gtttgaacac gataaacttg tagtccaagt cgaaaaggat cttatcgcaa agggattgcc
     6181 ttctgagttt gctgaattgc ttgctacaaa agatgcagaa aatgcgctag agcaagtcaa
     6241 aacattcgaa gcagcattta aaaaagcagt agctgatgaa gttaaaaaga ccgtacgaca
     6301 acttactcca tcaactgggg caggtgcaat atcaacacaa acaaactatg gggcgaactt
     6361 ggcgagtaag atcgcacaac aaagcaccac attattttag gaggaaaaaa atgaataaac
     6421 gtaaagtaac aacatcaaaa gagattctcc acaatctcga atacgaagct attacagtca
     6481 ctttagattc aagcacagtt ggcaaaaaag ttattccagc cggtacagtt ttggccggtg
     6541 tatcggattc tgtttttaaa gatcgcaaac aaaaagtaaa aactgtggca aatcacgagg
     6601 tcagcggaga gagcaatatt tgtggaattt tgttaaccga tgttgatttg acagatggtg
     6661 ataaagcagg tgcttgtgtt tatcgcggta ctgtcaacgc agataaactt gctgattcat
     6721 caattgcaga aaattttacg gaattggcga caaaactacc acatgttgtc tttattaagg
     6781 gaggtaagta agcatggcat tgatccacga aattatcaca tcggaaaaca tcaaaggttt
     6841 ttataatgct aaaaatgaga acattgataa aacgttaggg gaaaaagcat tcccaccaaa
     6901 acagcaatta gggcttaagc tatcctttat caagggtgcg gcaggaaaac ctgtgacact
     6961 taaagcggcc gcttttgata ctaaagtacc tctacgtgac cgcatggcag ttgagctgct
     7021 tgacgaagaa atgccttact ttaaagaggc tatgcttgtt aaagaggcag accgtcaaga
     7081 gcttaacatt atatctcaaa caaaaaatag tgatcttatt gacacagttt tagcggcaat
     7141 ttataacgat aaggtaacgc ttatcgcagg cgctaaagca cgtttagaag caatgcgtat
     7201 ggaagtgctg tctaaaggta aaatccacgt cgcatcaaac ggtgtcatga aagactttga
     7261 ttatggacta gactcttcgc aaacaactaa gccaagtgtt aaatggtctg aggcagagac
     7321 cgcgacacca cttaaagaca ttgaaggtgc aattgaaaaa atggcagaac gtggctttgt
     7381 gccagaagca attatcatga actctaagac atttagtttg attaaaaacg ctaaatcaac
     7441 tcttaaaatc atcaaaccaa tggcaccaga tggggcagct gttaccaaag gtgatttgac
     7501 gacttatatt gctgatgaac taggactcaa aattttgttt aaagatggta tgttcattgg
     7561 tgacgatggc aaatctcgta agtatttccc agatggcttt gcaactttgg tacctaacgg
     7621 caaccttggc tacactgtgt ttggcactac tccagagcaa tcagatctca tgggtgggca
     7681 cgcaacagat gcagatgtgt cgttggttga gactggtatt gcaatcacaa ctactaagac
     7741 aactgatcca gtaaatgttc aaaccaaggt atctatgatt gctttgccgt cattcgaacg
     7801 attggaagaa gtgcaaatta tcgactccat tgaccaagta taaggagggg gttatggctg
     7861 aagttattaa aacttttagg gataaagaaa ccactaacac ttactacgta ggagacgatt
     7921 acaacggaga ccgcattgat gagttgacag ctaaaggata cctatctggt gataaggttt
     7981 ctgctgccgc tatagagatt gaccttgaca aattaaaggt tgacgaaatt agagcaaaac
     8041 ttgatgagtt aggcgtcgct catgacccta aactaaaaaa gccagaatta ttagaacttt
     8101 tgaaacagtc agctagctag gaggtgttta tgcaaaagat aaacacagat agcattatag
     8161 ctaacgtaaa actcgattta ggtattgatg acaccttgca agacagtttg ctcaatatgt
     8221 tgctaaaacg tgttacagac cattttaaag cggaatacgg cgttgatgat atagacaacg
     8281 ccttttcgtt tgttttggaa gactgtctaa ttgctaggtt taatcgcaga gggtcagaga
     8341 gggctaagtc ggaagaggta gagggtcata aaacaaccta ctatgacttt ttaaatgagt
     8401 ttgagcctta cgacaaaatg attaagtcca accttaattt gattaaggat aattctcgta
     8461 aagggggatt gtacttttta tgagatatgc agataggatt acgtttgtta aggcgacaga
     8521 tgaacaatat gaccctgatt taggtgagta cacatatacc gaagtcatga tcaagacatt
     8581 gccttgtttt gtcatggact taggtatggc taaatctgtg cagattttcg gagactatca
     8641 aaaaacacga aaagttgttt atttgcgcca accttatacc gatttgttag atcactgtct
     8701 ctacaaaggc aaaaagtaca aggtacaggt ggataagcaa tttaatactg ttttttatct
     8761 ggagggagat gattctattt gtagctgata tatctttaaa agtagttgga acgacagggc
     8821 taaagaataa acttgaactt attgccaaaa aagaggctgt caagaagatt gttagagata
     8881 atggaaaaca actacacagg aaaatggtcc aaaaggcagt atttaccaaa ggtcattcca
     8941 ctggtgctac cagaatatcc atcacaatgc agattggtga tgatggtttt agtgttacag
     9001 taaaacctgg cacgcattat gcaggttatt tagaaaaagg cactcgcttt atgagtaagc
     9061 aaccttttgt gttgccagct ctaaaagagc aaaaagtaaa attcagaaaa gatttggagg
     9121 cgcttgtcaa atgattaaaa ctagagatca atctattttt gacgagatgt ttaagcgtat
     9181 tcagtcttta ggttttaaag tttatgatta caaaccgatg actgaggttc cttatccgtt
     9241 tgtggaaatg gaatctactg atgcagaata tattccaaat aaagatgaca ttaaaggctc
     9301 tgttgacctc gtactgtctg tttggggatt gcaaaaaaaa cgaaagcagg tgtctgatat
     9361 ggcatctgct attttttcac aagctatgtc agtggctagt tctgacagct tttactggtc
     9421 gttaaatatt cgtcaatcat ctatccaagt gttagatgac acaacaacag tgacacctct
     9481 caagagagcg attgtcacat taagatttaa tttaagatag gaggtcgcaa tgccaggacc
     9541 aagtagatta ggatccaaag atgaagacca ctccacacaa gaaaggaagg aaaaaatggc
     9601 agcgcaagat caagtacaat tagaagcaaa acaagggatt catgcaatcc tattattccg
     9661 tttgttaaaa gaagcatcat cagaaaaagc agctaaactc gcttttcaaa cggaacacga
     9721 agttggtaaa agtcgtgatg tcgacggtca aaagactaaa gatggtatta tccagtctgt
     9781 cggagcttta gaatacgact ttaaagcaac atctatttta gccaaaggtg acaagttagc
     9841 agcaaaacta gaagaagcca tggaaaaagg tgagcttgtt gaaatttggg atattgattc
     9901 cgaaaaagca agtgaagaag cttgatagca aaggtaaata tccagctacc tattaccaag
     9961 gttacatttc aagtttcggc gctaagaaaa atgcagaaga aaatattgaa attgaaatgg
    10021 aatttgccat taatggcgtt ggtcaaaaag gatttgcaac attgaccgaa gaacaaaaag
    10081 cagctgtaca gtacaaattt aaagatacaa cagcaggtta atcaacaagg ccagttaatt
    10141 actggtcttt tatttttaaa tttttaaagg gggaaaagaa taatgcaatt ggaaattaaa
    10201 ggtaaaactc ataacatcaa atttggcaca cgatttgttg ctgaaatgga taagaatcac
    10261 attgcagaac gtgaagggat gaagtttggc gctggtttgc aatcaactgt tccgtttttg
    10321 tttgagcgta acgttgtgac acttgctgag attatctata cagggacaat cacagagtca
    10381 ccacgaccaa gcttaaatga tatttacgac tacatcgatg aggctgaaga tattgagaag
    10441 cttttcgatg atgttttaga tgagttgcgc caatctaacg cgtcaaagtt gtttatcacc
    10501 aaactggaca aaaacatagc ggagatggca accgaagctt aaagagttca accaaaaatt
    10561 attcttcaca agaaagcttt gagatgattg tccttaattg tgttagatat cttggcatga
    10621 ctgacattaa tgagattggt cggttgactt tgtatgaata tgatttattg atgataggta
    10681 aagcgctagc ctctgtagac gaggcatata aagctcacaa gcaagcttgg ataaatcacc
    10741 aggtctcagc tacgaggctg gtcggtggtg gtaaaaacaa aagagaagtt cctgtttata
    10801 aaacattcaa ggaatttttt gattatgaaa cagaaatcaa gaagataacc aatgaaattg
    10861 atgaaagcta tgacaagaaa gcaatggatt tacttttaaa agccaacctt taaatagaaa
    10921 ggaagttaaa tgggagaatc ttattcagtt gaagcggtgt tgacagcggt tgataaaacc
    10981 tttggtaaga ctttaaaatc agcagttcaa tcaattgaag gactagaaaa gcgttcaaaa
    11041 ggcttctcgg cggtgtctca aaaggctggg tctatgttta aaagcatgct tggagctaac
    11101 ttagcaggtc aagctattac agcgctagga cgtacagttt catctggact tatttcgatg
    11161 atcggcgaaa tgaatagctc agcaaaagcg tggaaaactt tcgatgccaa tttagcagat
    11221 atcggatttg gcaaacagca aattcttgaa gctaaaacag ctatgcaaga ttacgctact
    11281 aaaacaatct actcagcatc agatatggcc agcacatatg cacagttagc tgctgttggg
    11341 gtaaaggata ctgggaaact cgtaaaagct tttggtggtt tggctgcatc tgctgaaaat
    11401 ccaaaacaag ctatgaagtc aatcagtcag cagatgacac aagctgtggg aagacctaca
    11461 gtagcgtggc aagatttcag aataatgctc gagcaagctc cagctggtat ggctaaagtg
    11521 gccaaagcta tgggcaaaaa ccttaatgaa cttgtagccg acattcaggc tggtagagta
    11581 aaaactaaag acttcctaga agcagtaaaa caagctggta acgacaaaag cttccagaag
    11641 atggcgactg aattcaaaac tgtggaccaa gccattgatg gcatgcgtga aggtttatcc
    11701 aataaattgc aaccagcttt tgaaaaagtg aaccaatttg gaattagagc gattgaagca
    11761 atcgggaaac aactcgataa aatcaatttt tccaaatttg ctgcaggcct tggtaaattt
    11821 ctcgagggcg tgaacattga tagtattatt tcaagaatat caacatcaat ttcatctatc
    11881 gtttctaaaa taaaaggatt ctgggacgga tttaatcaaa ctggagcaat cagcgctttt
    11941 tccggtgctt tacaaagtgt ttggggagcg ttaaaaaata ctgctaaagc catgagtgga
    12001 ggaagctgga agaccttcgg gtcaatcatt ggcgaaattg ttaaacatgt ttctaatttc
    12061 gcaagagtga ttggagatgt cgttggcaag atggatccga gtagactaaa aagctggata
    12121 gctactcttg cagctgttgg tggtggattg aaaatctttg agaaattaac aggtcaaagt
    12181 gttattggat cttttttaga caaaatcggc tcaaaattca aaatatttgg aaataaagcc
    12241 aaagaaggga cagaacaagc ctttaacgga gtcaaaagaa gtggtggcat tatcagtaaa
    12301 atctttaacg gtttgggtaa tatcgttaag tctgccggta cagcgatagc gactgctgca
    12361 aaaggtatcg caactggttt ttctatcgcg tttaaggggc ttgggtctgc catttctatg
    12421 gtaccgccag ctacatggct agctttagga gcagctattt tagcggtagg agcggctttt
    12481 gccttggcag gaactcaagc tgatggcatt agtcaaattt ttaaaactgt tggcgatgtc
    12541 gttgtacaag ttttacaaca ggtcactaac agtctagcta ctctaattcc tattattgta
    12601 agcgctattg gctccatatt accaattgta gcaggggcta tttctcaagt cgtcgcagca
    12661 gttgctggcg gattatctca gattattaca gctgttgcta atggtgtatc aactattatt
    12721 ggggctttca caggtctact tggtggtgtt tctagcgtca ttacctcaat tagtggtgtt
    12781 atccaatcgc tggcaggtgt aattacctca gtatttaatg gcatagcaac cattatttcg
    12841 tctgtagggt ctgcaattaa agatgtatta acgggtctcg gcagtgcttt taaaggattc
    12901 ggcaacggtg taaaatcagc cttagaaggc gttgggacag taatcaaatc atttggtagt
    12961 gcagtcagaa atgtccttga tggtgttgcg catattttcg attctatggg taatgcagct
    13021 cttaatgctg gtcgtggcgt caaagaaatg gctaaaggca tcaagatgct tgtagattta
    13081 tcgcttgctg atttagtcgc aacgcttgga gcagtcgcga caggtcttgg gaatatggct
    13141 ggctctgccg gtcagatgac tacgttaagt tctgccatga gcgaagtagc caatggtatg
    13201 gcgcgtctag gaacaagcgc tacgatagca attactggat taacagtttt tgctactact
    13261 ataacaacta ttcagaccgc aattgcaact ctaccaacaa tcctaactgc agccgctagt
    13321 ggttttaggg agatcgggga ttcggcaact gcagcagttg gtcgaatcca gacttttgca
    13381 gctggtacaa ctgttgttgc atcagcgttt gctagtatgc aatctatgat tcgatctgcc
    13441 atggctgcaa tagtaagcag cattataaca tcatttaacc aagctgcctc tcaaatacaa
    13501 tcaattttat ctcgggtgct atctcaagct aggacatttg gatctcaact agagcaacaa
    13561 atgaggcaat cgggacagcg ttcaggacaa aatcttgctc aggggttgtc ttctcaacaa
    13621 ggtgctgtta ttaatgctgt ttctagcatg gttaatgccg cggtatcaag agcaaatgca
    13681 ggtgctagtc ctatgcgtca agctggagcg tacatcggac aagggcttgc gcaaggtatg
    13741 tattcagcgc taggagctgt aacagcagca gcaaacgctc ttgtagcaca agctgagagg
    13801 gcagcaagag ctaaggcgat gattcactcg ccatctaggt tatttgcaaa acgagttggt
    13861 caatatatcc ctcaaggggt agccatgggg atatataaaa acgctgatgt cgttgatgat
    13921 tctgtaggtg agctatttga tagtatcaat agctttgatt ttaatattgc ggatagattg
    13981 acaagtattg gcgctagatt ccaaggtgtt gtcaaatcag aaagttcgca atcgttgtcg
    14041 cagcaacaag agtttgtaca tacagctcaa ccagcgtatg taaactttag tttaggcgga
    14101 aacgaatacg aagcatttgt aagtgacatc actaatcgac aagcaaaaat tgaaaaaatc
    14161 agactaaaga gaagcagctg gtagttgttt ctcttagttt tatgaaagga gtaaaatgta
    14221 cgaatttaac gatactatca gagggactcc gaaagttact ttcaatttaa aaacaacaat
    14281 tggcgaaaag gtattagaag aagagctcaa taatgattta ggtaccttta ggacattgac
    14341 cgtttctggt cgtgatatgg tggacttaga acaccagaca acaagtgttt tagggcgaga
    14401 tggcgagtat ttccacaatg ccacagttga agtcagaaaa ctagaaataa aagctaaaat
    14461 tactggaaaa gataaccggt caatgcgttt gcaatatgaa aaattaaaca gattaattgt
    14521 tagtcataat caagtttttt tatcattttc agacgagccg gacagaaatt atctaggcat
    14581 ctttaaatct aaagatatac cagaagaagt ttctaacgaa caaatcattg gcttggtttt
    14641 catctgttat gatccattta aaatgtcaga tataaaaacc aaaaaaggta atactgttca
    14701 aaatgatggc ctatttaata caaaacctat cataactctc aacctctcat catcaacaaa
    14761 agaaattagg ctgctacacg tcgaaagtca aaagtatatc agattaactg gtacttatac
    14821 tactgacgaa atcaagattg atatgacaac aggtaagatt acccagaacg gccgtaatat
    14881 tcttagtgat ttagacatgg ttaacagtcg ctattttgat ctattacctg gtaaaaacac
    14941 tttgcagtgt gataatgcaa cgattacagc tgatttcagg gaggtttatc tatgatttat
    15001 ctctttgata agctggagca attagttgct actgttggta ctgatgactt gctctcatgg
    15061 cattttaagg tcaaaaataa tgattgggat caagctagtt ttgaggtacc tgttgattat
    15121 gacattgagc cttttgttta ctttggtttt tttaactatg atccaagcca aaaagaggac
    15181 gtttttaaac tctttaaagt cattgattac aacctagaag atagcaagta ttataaaggc
    15241 ttagataagg ctgagagtga ccttgatact attgctatta tcaaagacaa gcgctttaga
    15301 caatcgtccg cagatgcttg tattgatgga gctttagagg gcactggtta tcaagttggt
    15361 aaagttgagg gcatttccga gatcaggacc cttagctatt attacatcag cccacgagct
    15421 gccatgatca agatgataga agcttttaac tgcgaattta atgtcagata cacctttgtt
    15481 aataacaaaa ttactagtcg ctatatcgac cttaaaaagc gatttggcaa gccaacagga
    15541 aagcagtttg agcatgggaa taacttatta aaagtcgtct atgaggaatc aacagatgac
    15601 atcgtgactt gtctgattgg ccgaggcaag ggcgaggaaa tccaatatga tgaaccagag
    15661 gcaaaggaag ttgaaggaca cttaccagag gcagaaaagc gtcaaggtta tggccgaaga
    15721 attgaattta gcgatgttgt ctggtcagtc gaaaaaggcg actcgataga caaaccagct
    15781 ggtcaaaact ttgtggcgct agatagtgcc agagaagaat acggattgtc tcaaaatggc
    15841 gagctaaaac accgatgggg ggtctttgtc aacgaggaaa ttgaggacaa ggcggaactc
    15901 ttaaaagcca catgggatca attgcagcgc ttatcaatac ccatcagaat ttacaaggcg
    15961 gaaatcttag atattggccc cgaaacgtgg aaaggtgact cagtagccat tatctacgat
    16021 gaggtaaaaa tagcttttga aactcgtgtt gatgagattg atattgataa gctaaacttt
    16081 aacaggtcgg tagtaactct cggtgattat agcgttgtcc aaaaccgcga agcaaggtca
    16141 cgcaaggaag ctgtccaaaa catgatcaat gatagcatag aaaacatcac cggccttggc
    16201 atgaacttac aagaattttt tcaaggtatt gaggaaaaaa ttgccactgg caaaaaagag
    16261 atggaagaca attggcgtaa ggttaacctt gaatttgata actttaaaaa attaatcgaa
    16321 caagagggac gtaactttag agagcgttta gaagctgaaa caaaggaact agatgaacgc
    16381 aaccaaaaag aactcgatga atttcgcgaa accctcaaaa atctgtcgct gcccgaggaa
    16441 gccattaaaa aaataaccga ggccatcaaa gttgatgata tcccatcgct aaaacaaagt
    16501 tttgacgagc tcaaaaacga agtcagcaag aacagcgaaa aatctcgctt aaatgctgaa
    16561 atcatcggca cgaacggtaa gacccgctat aacaaaaatc tcttggttgg tgaacctaat
    16621 cgcaccaaga cctatgatca ggattttgtg gagatagaag caaatgacgg tggttttaga
    16681 cgcggtgaga catacacgat tagctttagt cagacatgtg agttgctaaa aaaagtggct
    16741 atcacgctga cgcagccgca taacaaaggt ctcaagctgg tgctgacacc aaccaaggct
    16801 aagatggagg cgcagacttt tgacctaacc aaggacatag aggttatcag cgtctatcct
    16861 ttgagctaca gagctgtttt aacaggtgac tggtataaat ctaagcagat ggattttaat
    16921 gcggcagaag tgcaggattt agctctggag atgtcttata gagacgttgt cgatagcaat
    16981 aatgctagtt tgattttgga ttggtcctca aatccagatg ttatttttga tggaaatgga
    17041 ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg acaaaaaacg
    17101 agtgggagtc tagtgacatc attttgccac aaggccagct tgtctatgag tctgacacag
    17161 gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat caaggtggac
    17221 cacctggggc acaaggtccc caagggccag ctggcgaaac cggtccacaa ggcccaccag
    17281 gccctactgg tcaacgtggg gaaacaggcc cacagggtcc acctgggcca caagggccgc
    17341 caggagcgga cggtaaaatg acgtttgagc agctcacacc agagcaaaaa cagcagctta
    17401 aaggtgctgg catacaaagc atatcattgg attatgaggg ctatttgaca atacagctag
    17461 ataatggcca atcgtttaga tcagatatta gcttaaaagg tcctcaagga gagccgggga
    17521 tcaatggtat ggacggtcca agaggcgcaa cgggtcccca aggaccagct ggtgatccgg
    17581 cgagcatacc tgacgatgtt gtcagacgtg gtgagttagc tgcatatttg cttaaatcag
    17641 agtataaagc caaaggcgca ggctctgggc taagctacaa agttgtcact caatcagagt
    17701 atgatgatct gtatgattac agcgacaatg agttgatact cgtgacggag ggttgacatg
    17761 gcatataagc tttacactaa agctgatgtt ggtgacaaca tgttgcttgt tgttggccat
    17821 ttgcctgaca atacaaagcg attaaaaatc cagcgtgaga cgttagatgt attgagtatt
    17881 acccactata gctcttatga tatggtacaa ctcaagtcga cagtcaaaag atcccacagc
    17941 aaaaatacag ttgttactct tgtagctgca gctgctagca agcccaaagc taagccaaag
    18001 cacgttttaa actttgctaa ggctaataag gtctatctag gcagcactcg tgtaatagcg
    18061 gtttatctgg gtgatcgact gctctggtcc gacaaagaca gcagcgggaa caaaactgtc
    18121 tctgttgtgg ggagtcttga tatcagacaa tcacaaaaaa tgctgtattt gtacttaata
    18181 gcgtcagaca ttgcagatgt caaaagcaag cgcattaaat cgatagcgat aaatggcgtt
    18241 aacctgtcaa gcgctgcaca aatcaatttt gaggatagcg actattattg tctagtgaca
    18301 atcgagcgag ttgctaacat caaagagatc aaaaatatag cgcaaaaaaa caaaatcacg
    18361 ctagagtttt aggaggtaac aattgagcag agacccaaca attgtaatag acgagacaaa
    18421 cctcgttatt ggcacagatg gccgcatgca ttacacgttt actgctagtc aagacaacca
    18481 aaaggtcagg ctaaaaagca actgtttagg cacagcgcat tttaaccagc tgatgattga
    18541 gcgaggagac caagcgacgg actacgttgc gcccgttgtt gttgagggta caggacaggc
    18601 aacaggcgtc tttaaaagtc tcgaggagat gcttagtggc ctaaagtcaa ttaaactgga
    18661 gctaacagat accaaaaact caaatctgtg gtcaaaaatc aaattgacga caaatgggct
    18721 tttgcgtgag tatcatcatg atcatatctc gaccgagatt gtcgagacag cagctggtat
    18781 tgccaaacgg attgtcgatg atactggcca aaagctggca ctaatcaatg agactatcaa
    18841 aggtgttaag cgtgagtatc aagacgcaga tagacagcta tccgcgagct atcaagcaag
    18901 tatcgatggc ctcaaagccc agctggccaa cgacaaaatt ggcctacaag ctgagattaa
    18961 gctgtccgcc caaggcttgt cgcaaaaata cgacgatgag ctgcgcaagc tatctgccaa
    19021 gattacaacg acatctagtg gtactacgga agcctacgaa aacaaactcg agggcttacg
    19081 ggctgagttt actcgtagca accaaggcat gcggacagag cttgagtcgc aaatcagcgg
    19141 cctaaaagca gtacagcaat caactgcaaa acaaatctca caagagatca aggatagggc
    19201 aggggctgtt agtcgtgtgc aacaggatct agatagttac caaagacgct tgcaagacgc
    19261 agaggataat tacagtagct taacccagac cgttaaaggc ctgcagtcaa ctgttagcga
    19321 tcccaaaggc aaaatccagt cac
//
LOCUS       DARYLJ010000042        18690 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYLJ010000042 DARYLJ010000000
VERSION     DARYLJ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18690
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(9..83)
                     /locus_tag="TU746_001492"
                     /pseudo
     CDS             complement(9..83)
                     /locus_tag="TU746_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(77..733)
                     /locus_tag="TU746_001493"
                     /pseudo
     CDS             complement(77..733)
                     /locus_tag="TU746_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
     gene            complement(829..1794)
                     /locus_tag="TU746_001494"
     CDS             complement(829..1794)
                     /locus_tag="TU746_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL0891819.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            complement(1787..2563)
                     /locus_tag="TU746_001495"
     CDS             complement(1787..2563)
                     /locus_tag="TU746_001495"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL0891820.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            complement(2715..3878)
                     /locus_tag="TU746_001496"
                     /pseudo
     CDS             complement(2715..3878)
                     /locus_tag="TU746_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(3880..5601)
                     /locus_tag="TU746_001497"
     CDS             complement(3880..5601)
                     /locus_tag="TU746_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891821.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            6050..8056
                     /locus_tag="TU746_001498"
     CDS             6050..8056
                     /locus_tag="TU746_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL0891822.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            complement(8247..8657)
                     /locus_tag="TU746_001499"
     CDS             complement(8247..8657)
                     /locus_tag="TU746_001499"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0891823.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(8789..10138)
                     /gene="gdhA"
                     /locus_tag="TU746_001500"
     CDS             complement(8789..10138)
                     /gene="gdhA"
                     /locus_tag="TU746_001500"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL0891824.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            complement(10279..12055)
                     /locus_tag="TU746_001501"
                     /pseudo
     CDS             complement(10279..12055)
                     /locus_tag="TU746_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(12055..13800)
                     /locus_tag="TU746_001502"
     CDS             complement(12055..13800)
                     /locus_tag="TU746_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891825.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            complement(13905..15772)
                     /locus_tag="TU746_001503"
                     /pseudo
     CDS             complement(13905..15772)
                     /locus_tag="TU746_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(15765..16976)
                     /locus_tag="TU746_001504"
     CDS             complement(15765..16976)
                     /locus_tag="TU746_001504"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL0891826.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            complement(17076..17924)
                     /locus_tag="TU746_001505"
     CDS             complement(17076..17924)
                     /locus_tag="TU746_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0891827.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            complement(17924..18304)
                     /locus_tag="TU746_001506"
     CDS             complement(17924..18304)
                     /locus_tag="TU746_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL0891828.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            complement(18509..>18690)
                     /locus_tag="TU746_001507"
     CDS             complement(18509..>18690)
                     /locus_tag="TU746_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEL0891829.1"
                     /translation="ESFFGILKSEMFYGFEKSYHSLDELEQAITEYIFYYNNKRIKTK
                     LKGLSPVQYRTKSFQ"
BASE COUNT         5448 a         4343 c         3321 g         5578 t
ORIGIN      
        1 acgacatatt agtgaaagga tttagttctg tattgcacag ggctaagtcc ttttagcttt
       61 gctttaatgc gtttgttgtt gtggcttctg caagcatatt aagaactatt tcaagagtgg
      121 tcatattatc ccttagattt tcctttttca aacccttcag atttttataa cctcttgttg
      181 tcattccgga ccatgctttg gtgatttcat cagtaagaat tgcgtattct ttgccttttt
      241 gtatcccatg gtcatcccaa gcatcagtca gttcttttct tacctgaatg gcttgaagtc
      301 tttgatttat ccactcacgt gtatatccct tctttagata agtttctaag gctctgtcaa
      361 tcgtaagttc aggatcgata atttcatcaa ttcgttcttt tccaacctca gcaagccata
      421 acttaaaagg ttctgcttta ggggatggga tggactggat aatacggaat attccttgca
      481 tatctgctac atcagttaaa cgcatttttc catctgttgc tttcattttc aactgcttac
      541 aaattgtaag cagttcattt ccttcttctt ttaatctctt ttttagtaca gcccaatagg
      601 tactagcacc tcttacgttt tcttgttctg tcaaaactcc aactacatcg actactgaaa
      661 aataccactc ttctttttct tcgtcccaaa tggagcgtat ctctttattt tcatacaatt
      721 ttatttcgtc cattctgaca cctgcctctt ttatatctta tcctgttaaa caggtctttt
      781 ccctttttaa taccttatat tataccttaa atttataatt ttgtcttttc actgaccaat
      841 atattcctta aagtaaattt ccaatgcttt ttctataatt tcttctacat cttctttcct
      901 ttcatcatga aaaaactttt tatagacact ctgagatagt ttgatattct gatacttttt
      961 taccttcgtt tttttcaagt tcagcaagta tgttataacc atctcttgat tcagatcttc
     1021 ttgtctgttc atcagatgga gtgctttggc atcgcttggt tttaaactta gttccaattc
     1081 ttcgcacttc tgatacagat attcctgtat ttctttggaa agataggata aatctactgc
     1141 catcgtcaaa cctattttat cttcatccac atcttttttc caagacttag ataattcatt
     1201 taatcttagg taccttgcaa tagatgcccc tgaaagatta tattcttttc caagtgtttt
     1261 tctgctgtct attttatctt cctctttact ttccttttct ataattccct gatctaaatt
     1321 gtttatctcc ttttgcaaat catttctctt gccctgactt gctatttttt catatctcat
     1381 tttaagaaca agggcttttt ccgtcggcag taaatcggag aaagaacgct gtataaggtt
     1441 tgtttcaatt acataggtat aggcttcttt atccgttaga ttttctttaa caatacaagg
     1501 aatacttttt atttttgtaa ttcttgctgc atttactcta ttgtgtccgg aaagtatttc
     1561 atagttgtta tcttttttca agacgataat tggattaaga actccgtttt ccttaatgct
     1621 ctctaccata tcgtctaatc tcttacctgt atataaagta aacggatgat tatgataatt
     1681 ttcaagcaaa tcaagttcta tattctgtat atttccttgt tccaaggcat ttccatcatc
     1741 aagcaaaaaa tctacggcat cggtgatttc tctctttaga agttttttac tcatagcaga
     1801 tctcctttgc cagattgtca taggcaatgt ctacactact gccttttgca tattttttta
     1861 tgctttgccc gctatagatg gcttccccaa ctttaactgt tttcggaatt ttggtttgaa
     1921 agaccttgat tttcttttgg aacatttctt ctacttgctc catcagtgtt ttggacagat
     1981 tggttctatt ctcacacatg gttagtaaaa tcccctgcac tttcagtttc ggattcactc
     2041 tcttttttat tttttgaaca gtttttaaaa gttcattgat tccaacaact gcgaacagct
     2101 gtgtatccgc tactataagg acactgtctg aggcacaaag agcatttata gtcaaaacac
     2161 taagtgatgg tgatgtatct atgagaatat agtcataatt ctcttttacc ctcctaataa
     2221 tttccgataa tatacgttca cttcctgttt ctgctctcat ttgtgtttca acggcggata
     2281 agaaaatgct tgaggggata atatctatct catcataaga tttggtatag ccctctacca
     2341 aatagctttc ttcttcctcc agttctacca ttaacaaatg ccctatggtt tttatatttt
     2401 ctgtatttcc catatcaaaa catcttgtaa gattagcttg tggatcaagg tcaatgacta
     2461 atactttttt ccccagttct tttagtgaat aggcaaggtt tagagttgta gttgtttttc
     2521 caactccgcc ttttcgattg gctatggtta tcacttctgc cataaagtcc ctccttcttc
     2581 tctatacaga gatttcattt tatgctatac ttttatataa ttttagatat aaaaaaagat
     2641 gatagcctca atccatcatc aagtttaaaa gttttgcgga agcctttaac cattgatttt
     2701 acttggattt attgtactat catcattata gcattgtccc cagagccagt atgccctact
     2761 agggcaaccg tctccccttt atcagcatga atggtaatat cagataaaac tgtcttgcca
     2821 ttttcgtaag caaaatacac cttggtaaaa tccacagtac catctgttag ctcaattgct
     2881 cgtgctttat ccggctctgt ctgcgcctca agcagcttca ttaggcgcgt tcctgtcgct
     2941 gttgagcgct gaatattagg tagctgccta accagcatac ttaataaatc aaacaagcgc
     3001 agcaaataat tgacgtaaat aaagagctta ccaactgtga tgcctgatct cccctgcaag
     3061 aactggtaac caataacagc caaaatagcg gcaatcatgc catactttac caattccgtc
     3121 agggtccatg aagcaactga ctctgcaaaa ataatcctat catcagctgt tttcatctgg
     3181 tggatctgct cttcaaattc ctctaagatc gtatcctctt gatgataaag ctgaataata
     3241 gaaacaccat tcatggtttc gttgacttgt gtgttgacag cgctcctagc ctgataaaaa
     3301 tccttcattg gctggtcagt caagctttta tacagccatt gcatgccata aaagagtggc
     3361 ataataagca gcaacagcaa gcctgacttc acatcaaggt aaatcatcac cacataaata
     3421 aaaataattt gtgaaagact gacaataatt tgagacaaaa ggttatcata aaattgattc
     3481 ttcagggttt cagtatcatt aacaatccta gttgcaatct ttcctgcagg ctgatgatca
     3541 aaataagcta tcggcagcct ctgcatgaca tcaaaggctc gattacgaag attagcaacg
     3601 atcctattag aggaataaac cagcattcga taagagatat aacgcaaaac tgctgttatc
     3661 acaattaaca gcaaatacag caggagcaag cgctgaaagc cttcaatcgg tacctctttt
     3721 cctctagcta tcggagtcaa gtaatgatca atcgtttgtt gcaacaataa gggagccatc
     3781 tgacctccag ctgttgccac tagcaaaaag cctattgcca gggaaaaagc caaggtcaca
     3841 gctttaattt cttttattaa ttttataaat agggtcatct taaacctcct gagcctgctg
     3901 acgctggtac tgttcataat accagccctt ctgagctaaa agttgttggg gctgaccttc
     3961 ctctactatc tgcccctgat ccagaacaat aacccaatcg gcatgctgaa tcgcagacaa
     4021 gcgatggcta acaataagtg ttgtctttcc ctttctttcg tcttgaatgt gtcgaataat
     4081 atcagtctct gttctagcat caactgccga cagggaatca tctaaaatca gcaaatctgg
     4141 ctgggacaaa aaggctctgg caatcgaaat acgctgcttt tgacctcctg aaatagacag
     4201 accacgctct ccaatctcag tatccaagcc ctttgccatt ccttgaacat cacgcgtaaa
     4261 ggccgcagtt tcaatcgcct ccaagatttc ctcagttgta gctgcctttt tccccatcgc
     4321 aatgttttga gcaaccgttt ttgaaaacag gatatgctcc tgtggcacat agccaatttg
     4381 acgctcaagt gattgacgct tataatccaa gacactacga tgattaatca tcagctgccc
     4441 ctgcccaaga gggtattgtc tcaaaaactg cctgacaagg gttgttttac cagagcctgt
     4501 tttaccaaca atccctaagg tttgtccctt tttcagggtt aaattgatct tttctaagct
     4561 aggcctagaa ctattggcat aggtaaagct atagtctata aaagcaatct gatcaaagct
     4621 ctctaactca agctggccat caggctccat atcatcactt gtttcgatga gttcattaat
     4681 cttaccaaaa gaggtctttc ctgtctgata aaccaaaata aagtctgaca gcatgccaaa
     4741 gggctccacc aaagacacca gataaagctg cagcgcaatg acttgaccaa gtgttacctc
     4801 tgagcttgct atgagctgta ggcctaccat taaaatgatt actgtactaa tggcaatcat
     4861 gacgctgtaa agaggaaagt acaaggcacg atacttggcc acctgattcc atttatctgc
     4921 caaattctga gtcttttgag caaaatgaag tgccaaataa tcttttttac tgtaagcacg
     4981 catcactcta atgccctcaa cggtttctag tacctcatca ctaaggcttg aaatcgcctc
     5041 acgcgcctct tcaaccaaat gctcttgctt tttcgtcaca ccatagatca tcaccatcat
     5101 aagcaaaatc ggtactattc ctatcaaggt cattttccaa gaaatcaaaa acatggtcgg
     5161 aataataaaa gcaatcatac caccagcata taggataatc atcaagccat agccgataag
     5221 gtccataagt gcttcgacat ctgttgaaaa acgcgtgatc atgtcacctg agcgaaattt
     5281 ctcataaaaa ggcgttctca taaaaacaag ctttcgaaag gcacgctgct gaatatcaaa
     5341 cttaaaatga actgcctcct gaaataaatg aagatgccac aaataagcaa ccccataaga
     5401 cactactgcc gtagccaaaa gaatgataac atgcctcacc aatgcccctg agcttagctg
     5461 atgccttgac atcaaatcaa ccaagtcttg aataaccctt gttggtatca caagtgaggc
     5521 atcatatatc actaaagtca ttgcaataag gatataaatc catttctttt gcttaatatg
     5581 ttgaacaatt aaggtcagca tcatatcctc catttctgaa ctaacctatt tcaagctgtc
     5641 ttaaaatagg atttttgcac acaaaaagcc cgcaataaga tatccttcct accgcgggct
     5701 ctactatttc tatttagtga aactaaaaga aactaactgt tttggttaga aaggagacta
     5761 tcgtaataat ggttaaatag ttgaatgaaa cggatcatta ttaatttctc ctttctttta
     5821 atctgcctaa catcttatca tagaatactg ggcttgtaaa gccttttttg gatagttctt
     5881 ctattttttt acaaaaaacg cttccaatgt ttgcatttta aacgttttca gtgattagca
     5941 aacgctatcg ttgaattttt gttagctttt ttattaattt ttgttgaatt ctcatttaaa
     6001 taatagtaca cttaacttgt gacaatactt taaactttta ggagcgttta tgaaaaagca
     6061 ttttgtttta aaaagtagtg ttcttggtgt ctttgccgga gtttctatgc tagtaaccgg
     6121 cgtgcaggcc gatcaggtag acgtgcaatt tcttggtgtc aatgactttc atggtgcctt
     6181 agacacaacc ggctctgcct acatgccaga aggaaaggta tctaacgctg gtaccgcagc
     6241 acaattagct gcttatctgg acgatgcaga ggctgacttt aagcaaacaa gcccagatgg
     6301 gacaagcatt cgtgttcaac caggagatat ggtcggagct agtcctgcta attctggact
     6361 attacaggac gagccaacgg ttaaggtatt caaccagatg ggctttgaat acggaaccct
     6421 tgggaatcac gaattcgatg agggcttagc tgaattcaac cgtatcatga caggcactgc
     6481 acctgctgaa gactcagcta tcaacgacat tactaagcaa tacgagcatg aagcttcaaa
     6541 tcaaaccctt gtcattgcaa atgtcgttga caaggagacc aacacgattc cttttggctg
     6601 gaagccttat gctgtcaaag aagtcccagt taatgataag tcagtcaagg tgggctttat
     6661 cggtgttgtg acaacagaaa ttccaaacct tgtcctaaaa caaaattatg aacaatatga
     6721 ttacctagac tctgcagaaa ccatcgttaa atatgctaaa gagctccaag agcagcaggt
     6781 caatgcgatt gttgtcctag ctcatatccc agcaacaagt gataacgggg tagttcatga
     6841 tgagatggca gcagttatgg aaaaggttaa ccagctttat cctgagcata gtgtggatat
     6901 tgtctttgct ggtcacaacc accaatacac caacggtacc attggcacaa cacgtgtcgt
     6961 tcaggctgtt tcacagggga aagcctatgc agatgttcgt ggaacactag acactgacct
     7021 caatgatttt gtagccactc ctgaagcaaa ggtcattgcc gttgctcctg gcataaaaac
     7081 aggcaatgcc gacattcaag ccattgttga tcaagccaat gacattgtca aaaccgttac
     7141 cgagctaaag atcggtacag cagctacctc ttcaacgatt tctaaaacag aaaacgaaga
     7201 caaggaatct cctgttggca atttgataac aactgcccaa ttaaccattg gtagaaaaac
     7261 cttccctcat gttgattttg ccatgacaaa taatggcggt attcgcgctg acttggtggt
     7321 caaagaggat caaaccatta cctggggagc tgcacaggct gttcaaccat ttggcaatat
     7381 tcttcaggtc gttcaaatga ctggccaaca aatctatgat gtcttgaacc aacaatacga
     7441 tgaagaccaa aaatacttcc ttcaaatgtc tggactcaaa tacacttata cagctaatga
     7501 ggctaacgat ccttcaacac cgtttaaggt agtaaaggct tataaagata atggtgaaga
     7561 aattgatcca gcagctcaat acaccctaat catcaacgac ttcctatatg gcggtggtga
     7621 tggcttctcc gtctttaagg acgctaagct actaggagcc attaatcctg atactgaggt
     7681 ctttatcgaa tacatcaagg accttgaagc agctggaaag actgtaagtg ctggtattaa
     7741 cggtgtgaaa acctatgtca ctgccagtct tgaaggctct actcaaagtg atcataccgg
     7801 caagcacgag atcatcaacc gcgtctttaa gaatcgtgag ggcaaggtgc ttgctactga
     7861 gcttgtctct gacctattta cgcctgctca aaatgctaat cctgccacaa gcatcaagcc
     7921 tctagcagct aaaaagcaag ctaatgctgc cttaccagca acaggaacaa gccagcattc
     7981 tgctgctgcc atgacaatcc taggactact aaccttaact ggtactagcc ttttcaagaa
     8041 aaaggaaggc caataaaatc gtcctagcca taacagcaat aaccgactgt atcttaagca
     8101 tacagccggt tttctgattt atgtgacgtt tatttgtttc gcacctgttg agcaagacaa
     8161 ataaaccacc catctatgga ctgccctcat tcgttagatt ttctgtctaa cttttggggt
     8221 gcagttcact aacgggtggt catgatttaa atcaatatgc cctccagatg atccagctca
     8281 tgctggcaga tttgtgcagg caggcctgtc aatctcaggg atttcttgtg ccaatgtgca
     8341 tcaaggtaat caaccttgat ctcctgataa cgctttgtct tacgttggcc gattagtgat
     8401 aggcaggatt cctctgcctc aaacgcttca cgcttagcaa ttaatacagg attaaacatc
     8461 accaaatcca caaagcccat gctaataata ataaccctct tgttttcccc tatcatatta
     8521 gcagccagcc ccaggcagct atcacgataa taagctaagg tatcctgcag gtcttgacca
     8581 atccaaaggt cctttttcgt tgctggctgt gctttttgct gcaagaaaaa ggtgtccttc
     8641 acgatttttt tgatcatcag cttctccttg attcattgct ctaatcggca tgcattgtct
     8701 agatgaccga tcgtatatct taacgtcatt gagctaagat taatgtgcta accctactga
     8761 tatattcagc atataccagc cacagctctt aaacgattcc ctgtgctgac atggcctgag
     8821 caactttgag aaagcctgca atattagctc ccaccactag gttgccttct tgaccacatt
     8881 ccttggcggc agcggctgct ttttgataaa tagccttcat gatgtcatac aatcgatgat
     8941 ccacctcttc aaaggtccat gcggtacgtc cgctattttg tgccatttcc agcgcagaaa
     9001 ctgctacacc gccagcattt gctgctttag caggtccaaa aagaacccca gcctgctgaa
     9061 attgctcaat agcctctaag gttgagggca tgttagcccc ttcgacaaca gctttaaccc
     9121 catgctcaat caaggcttta gcatctgcct cttgtagctc attttgagtc gcacatggaa
     9181 aggcaaggtc tgccttaata gtccagatgg atccctcacc agccggtgta aacacagcag
     9241 ccgggtgact ctctagatag gtcttgatac gctcacgctt cacttccttg atttgcttta
     9301 gggtctcaag atcaatgccc ttatcatcat aaacgtaacc agaggaatcc gacactgcta
     9361 ataccttaac acctaaggcc tgcaattttt ccgttgcgta aatggcaaca tttcctgatc
     9421 cagatacaat agctgtttta ccagccaagt cctgcccctt agccgccagc atttgctgag
     9481 caaaataaac cacaccatag cctgtggcct ctgtgcgagc caaagagcca ccataagcta
     9541 agccttttcc tgtcaacaca ccattcttaa agccattaag acgcttatat tgcccaaata
     9601 aatagccaat ttcgcgagcc cctacaccaa tatcaccagc aggaacatca aggtcaggtc
     9661 caatatgcct ttgcagctct gtcataaagc tttgtgtgaa gcgcatgatt tctaggtctg
     9721 atttgccttt aggatcaaaa tttgatcctc cttttcctcc tccaataggc tgaccagtca
     9781 gagcattttt gaaaatctgc tcaaagccaa gaaatttaac tatagactgg ttaacagaag
     9841 ggtgaaagcg aagccctccc ttatatggac cgatagctga tgaaaattgc acgcggtagc
     9901 cacgattaac ttggaccctg ccctggtcat caacccaagg caccctaaag gaaatcacac
     9961 gctcaggctc aaccaagcgc tctaatagat tttcctcaat ataattaggg tatttttcaa
    10021 aaacaggaat caaggaatca aatacctcct tgaccgcctg aagaaattca gtctcatgcg
    10081 gattatccct tttgacctta tcaaaaacac tggctacata gtcttttgct gataccatta
    10141 tatatcctct cgcttcttca ttctatttta agtatagtca atattataaa ttttctgaat
    10201 tttgatgtca agcttttact atgatctaaa gcaaattaaa agagccttgg aacgattcat
    10261 tccaagaccc taagcttttt aagactgact ggtcttaaat tggctatgat aaagctcata
    10321 atagaagccc ttagcagcta ataggctgtc atgattcccc tgctcgataa tctgaccatc
    10381 ttttagaact aaaatcttat ccgcctcttg aatggttgat aagcggtgag caataacaaa
    10441 gctagtcctg ccaaccatta atcgcttcat cgccttttga atcaaaagct ctaaacgtgt
    10501 atcaacagac gaggtggcct catctaggat tagcagcttt ggatctgcta agagagctcg
    10561 agcaatggtc agcagctgct tttgccccag ggaaatattg ctagattcct gattcatcac
    10621 catatgatag ccacctggca atgtcctaat gaaatgatca acattggcag ccttagcagc
    10681 ctcaattatt tgttcatcag tcgcctctaa atgaccaaag cgcaagtttt cctgaatgct
    10741 gccctcaaag agccaagcgt cctgcagcac cataccaaac tgacgcctat aggcttgacg
    10801 tgacaactga cgaatgtcct gaccatcaac tgtgatagag ccctcattca catcataaaa
    10861 ccgcattaat aaattaatca gggtggtctt gccggctcct gtcggaccaa cgatagctac
    10921 catctcacca ggcttaacct ctaaattgaa atttctaatc agaggattgt ctgctgtata
    10981 gctaaaatca acctgattaa aggacacctg acctgttaaa tcatgttcta aatgctcttg
    11041 ggcaatagtc aattcatctg cctcatcaag cactgcaaag atacgttcta aggatgactt
    11101 ggcactttgc agtggaccag ccagctgtgt tatggtctga ataggctgac tgatttgcca
    11161 aatgtactga acaaaggctt gcatgtttgt tcccgattgt caggcggcct gctatcacct
    11221 gtaagccagc gattaaggca acaatcatgt aaacagaatc tgaaataaaa tgcagaactg
    11281 gcatcatgat cccagaaata aagctggcct taaagcctac ttcttgtaat cgctcagtga
    11341 tctggtgaaa ttcctccttt gaggcttctt cacgaccata cagttttaaa atattaaagc
    11401 cggtcaaatt ttcctgcaca aagccattca tttctcccaa aatattagcc tgcgctttaa
    11461 aataaggctg tgattttttt aaaacaaatc gagaagcagc atatatcaac gggatagcga
    11521 taatcacaac agaggctagg ggggcattaa tatacaagac catgccaacc accaaaataa
    11581 gggtaaaaaa ggcgttaaca atctgtaaaa aggactgctg taaggcatta gagactgtct
    11641 caacatcaga ggtaaaccgg cctagcatat cgccgaactg atgcttatca aaataagaca
    11701 cagggatacg attaattttt tgactgaggt ctcgacgaag atcacaaatg cttgattgca
    11761 cagcccttgt cataaaatag tttgaaccat aagagcctaa ctcgtaaaca agggccctaa
    11821 tgatatagag agctaaaaga aaggcgatat aggttttatt aatgcctgca ccagagactc
    11881 cctttgctat gtctaatagg tttgcagata gctctgttat caccaagcca agaacaaagg
    11941 gctctaagac actcatcaca gcactgacta tttttaaaat aatggcagtt attagtgaga
    12001 gcctataggc actaaggtag gtccaaattc ttctaaacac atgcttttca gtcattaatc
    12061 cccctcctct tttgtcatgt cttccttgtt tagctgagaa ttggcaattt cacgatagat
    12121 ggcattgctt gtaagcaatt cctcatgtgt acctcggcca acaatttctc cctgatccaa
    12181 gacaatgatt tgatcagcat ccataatcgt gcccaccctt tgagccacaa ttaagaccgt
    12241 tgcatcttgt gtcacctctt tcagccgtct gcgtaattca gcatctgtct tgtaatctag
    12301 ggcagaaaag gaatcgtcaa agatatagat gtctggctgc ttgaccactg ctctggcaat
    12361 agacaggcgc tgcttttgcc ctcctgatag attactgccg gcctcagcta gatgggtttg
    12421 atagcccttt tcacgactgg taataaagtc cttcgcttgg gaaacctctg ttgcctgctc
    12481 aagctcactg tggctggcat ctgacttacc atattttagg ttttcctcaa tggttcctgt
    12541 aaatagcagg gctttttgag gaataaagcc gattttagaa cgcagcgctt ttaattgata
    12601 atccctgaca tcaatgccat caaccaagat tctccctaag gtcacgtcat aaaatcgtgg
    12661 gatcagatta accaaagatg attttcctga acctgtcgag ccgataaaag caatggtctc
    12721 tccaggccta gtcttaaatg agatgttatg taaaactgga ctttccgttt cacccggata
    12781 ggcaaaggtc acgttatcaa attctagata accacgtgtt gtgaacgctg ttataccatc
    12841 ttcattttta gaaatcgaaa tcggcatatc cagcacttcc ttgatacgct tgcttgacac
    12901 tgctgtttta gggtacatgg taaagaggtt ggcaaacatt aaaaatgaaa aaagagcatg
    12961 aaagctatat tcgataaagg ccaccaaatc accaatctta aactgccccc ttgccaaggg
    13021 atccaaggca aaccagacga tccccacaat catagcaatg ataatttgca caaataaggg
    13081 ctctgttaag cctgtcaagg taaatagtcg ctttgagatt ccagaatagt gatcattgcg
    13141 cttattgaag cgctcttctt gaaagtcttc tcttgcaaag gctcgaataa ctctcagacc
    13201 tgtcaggttt tcacgcacca attggttaat acgatcaagg ctctcctgct gcttttctga
    13261 taagggtctt gtctttatcg caacataaag caccacaata actaaaaaag gcatggcaac
    13321 agccacaatc caagccaatg atggactggt taaaaagatc atcaccactg aaaagatcat
    13381 catcaaagga gttacgacac ccagcctcaa ggacatttca gcaaattgca tcaaaacaaa
    13441 ggcatcattt gttatccgag taaccaggga ggctatgcca attttttcat attccgaatg
    13501 cgaataatcc tgcaagcagc tatacatgtc attacgtaaa tccttgatca tgttggtggt
    13561 tagcttaccc gaagcatagg ataaaatcac ccgtccaatg acacctaaaa gtacgataat
    13621 aaacatcatc agagcccaaa aataaagagc cctttgatcc tgctgcataa cgccttgatc
    13681 aatcatacga gccaatattg ttggtagccc cagattgacc agaacaaata acaagccacc
    13741 cacaatatcg aaacaaatcc atttaggtct tgtttttaaa taggaccaaa ttaaagccat
    13801 tcatttcctc ccaaataata gtgatatgaa aagaagcgca agctagcact tctttttgtc
    13861 tataactagt ttaacacaaa aatatgaaat tgacacataa ttaattattc ttctaattcg
    13921 cttaggtaat caaagcgctc ataggcttca agcagctcaa gattccgctg atccagctcc
    13981 ttttgatatt gtgccaattg gtcgtaatca cttgccgctc tgagcatttg ctcctcaata
    14041 gtagctattt gttgctcgat agcagctagc ttttcttcaa tagctgccca ttcctttttc
    14101 tcaagatagg acattctctt tttagaggtg acctgatggt cagtgccagc tttttgctca
    14161 ctgacagcag gctctatgac ctctgcttca aaagcctttt catctaaata gtcgctatag
    14221 ttaccatagt attctctgat agctccatgc tcaaaagcca atacttttgt tgcaacctta
    14281 tccaagaaat accgatcatg actcactgta atgaccggac cagcaaattg agctaaaaaa
    14341 tgctccaaca ctgtcaaggt tgcaatatcc aaatcattgg tcggctcatc cagcagcagg
    14401 acgttgggct tttcgatcaa gagctttagc aaatacagtc ttttttctcc ccgcctgata
    14461 gcttagcgat taaggagcca tgactagaac gcggaaaaag aaattgctcc aaaagctcac
    14521 tgatgctagt ggtgccaaca ctggtcttga cctcatctgc cacctcctgc aaatagctaa
    14581 tcacgcgctt gctgccgtcc atatccttga tttgctgtga aaaataacca atacggatcg
    14641 tctcgccaat ctctagctga ccagctgttg gttttaagtc accagtcatc aagctaagca
    14701 gggtggtctt tccagcaccg ttagctccaa caatgccgat acggtcctta ttttgaatga
    14761 tcaggttaaa atgctcaata atggcctgat caccataagc aaaggaaacc tccttgaaat
    14821 taatgacctt cttgccaata cgactggctt caaaggccat atctaattga tctataggcc
    14881 tttcctgatg aaggtccttt tttaactgtt caaagcggtt aattctggcc tgctgcttgg
    14941 tcgcacgcgc ctgtggctgt gtcctcatcc aagccagctc ctgtttatag agctgctttt
    15001 tcttatgcaa atgagctgct tcgcgctcgt cttgctcagc cttcagacgc acataatcct
    15061 ggtaattgcc ctgatattca gtcacatgag ccttatccaa ttcaaagata cgtgtggcta
    15121 tactatccaa aaaatagcga tcatgtgtaa taaatagaac agtcctttta gaggtcctta
    15181 agtaatgact taaccaagcg atggtatcaa tatccaaatg attggtcggc tcatctagca
    15241 gcaacaaatc actggctcca agcaagacct gagccagctg tacccgacgt ctcataccac
    15301 cggacaggtc acccactctc tgatccagat tgacaatacc aagctttgat aagaccgtct
    15361 taacctcact ttcgatcgac caaacatcta atcgatccat ctcagtcatc acctctgcta
    15421 gcttttcctg attgctatct gaatagtcag ccatcaacag ctcatattgg cgaatcagct
    15481 gcatttcctt taattctagg gacagaacag tatctaaaac agactgatca tcatcaaagt
    15541 ccggctcctg tgttaaataa gatatacgat agtcatttgc ctttgaaaaa ggtgagcggt
    15601 caccatcaaa gcccactttt tcagaaataa catcaagcaa ggttgttttt cctgtcccat
    15661 tgacaccaat aatgccaatg cgatcaccag catgaataat aaaggaaata tcctgaaaaa
    15721 cggtcttatc tccaacagac ttcgtcagat gttcaacgat aaaatcactc atttagtagt
    15781 tcccttctaa caaaagcctc aatgtgttct ctttgattga cgagacgccc ctctacaatg
    15841 gcctgctcaa tctgatttaa aagcattccc agctgtggtc ctggcttcat tccaagctca
    15901 cgaatcagat aagagccatt gaccacaata tcatgcttat catggatcgt cagctcctga
    15961 tacaagctct caacacgctt ggcctcactg accaagccct gtgcctgtcg taaatcgtca
    16021 acgagtaaag ccaagtcctt gccaaacgag taaatatccc atttttctag ctgtctttct
    16081 tggcgaatct gataaagaga ggccatcatc gtaaccctac gctgaaaatc attagaggtt
    16141 ttccaagcct ttaaaaaggc tttaggctga tcaagctcca gcataaccag caaataggcc
    16201 caagcctgat gattgtcctg aaacacataa tccgctgcta aggttttcag gtacttttgc
    16261 agggcttctt ccttgcccac taagcctggc aaatagttaa aggcctgaca tgccaccata
    16321 gctaagatac ctttacgcca ttttggggcc attaaaagct tatcaagctc aataaaagag
    16381 cgctcaatag aaatcttctc cagcaaggga gcatggcttt tcattgcttc aaaggtctca
    16441 gcctcaatat caaaatctaa gctggcagca aaccgaaagc ctcgcataat ccgcagggca
    16501 tcctcctcaa agcgctcctg aggccttcca acagctctta gaagcttatg ctttaggtcc
    16561 tctaagccat taaagatatc aataacctgt ccgtcctcat ctaaggcaag agcattgaca
    16621 gtaaaatccc ttcgttttaa atcctcttcc aaggaccgaa caaaggatac ctgactaggg
    16681 cgcctataat ccacataaac gtcctcagtt cgaaacgttg tgatctcata ttcactgcca
    16741 ttttctaaaa caagcactgt gccatgctca atcccaacat caattgttct taagaaaata
    16801 gcctttgtct cctctggata gcagctagca gctatatcaa catcatgaat aggcctgttt
    16861 aataagctat ccctcacact tccaccaaca aaataggcct caaagccagc ctgcttgatt
    16921 tttttcacta ttggtaaagc cttctgaaat tcagaaggca ttgtcattaa tgttatcatg
    16981 ttttaatcta ccacctaaaa gctcctagag ccttgtcata tgcttcccgt taaaggctgt
    17041 catatcaagc tcagattggt catgggcaag cctctttaga caagaggcgt tatgccaaag
    17101 gcaacagctc cttctccaag atgggctgca atcactgcac caaaatgaac ctcctcaaca
    17161 gggcaggtat agccattatc caacaagagc tgctttaaga tatcagcctt atcctgcgct
    17221 ctagcatgga taattgatac ctcgtactga ccactagctg tcaattcctt taagatatca
    17281 accaagcgct tcatggcctt tttttccgtt ctaacctttt catagacgac aatctttcct
    17341 tcactatcaa agcgaagaat tggcttgatg ctgagcaaat ttcccagcaa agcagaaccg
    17401 tttgataagc gtcctccctt gaccaaatga ttcaaatcat caaccatgat aaaggctgtg
    17461 gttccagcga tttgctcttc tagcttatcc ataatctctg caaagctcaa gccttgctga
    17521 gaccactcta aagcatttct aaccatgctg cctaatggtg ctgaggtgat tttactatct
    17581 ggaaaagcaa tggtcaactc agggtgctcc tcgatgagaa attgaatatt ttgccaaaat
    17641 cctgaaatac cactagccaa gaacaagcca atcacatgag tatagtgctc agttgacaga
    17701 cgccctagta aatcatctaa ttcagagagg ctgggctgac tggtttttgg cagctcttga
    17761 gattctctca tgctttggta aaaggcttca atggtcaggt tttgtccttc gacatagctt
    17821 tgaccatcta tgattacagg tatgtctaat acaaaaatat cggcatgctc cgctaactgc
    17881 tctggaaggt gagctgtatt atcagttatt attgctaact tcattaactt ttaaactcca
    17941 aattaatacc aggacgatcc aaggcaattt ctgtcacttc gtaggtcaag cgcttcacca
    18001 tgtctaataa tggagcagcc aaggattcga cctcctcttg tgtaaattca ctaggcttat
    18061 ccaccaagcg tcctaaaata cgaaccatct gtgaaatcac accactaatc acaaactctt
    18121 ccttgacaat gacaaattgt aaaacagaaa caatagccgt ctctttattt tccacatctt
    18181 tattaatcaa ctgaaaggtt acttcaaagt ttgtttccgg tgttccattt tctttttccc
    18241 attctaaatt tctggcgtca taatggtact gattgacaaa ttctttttca cgtactaatt
    18301 gcatgatttc gttctcctta atggcgatat gacccattat agcatagatt tgacgaatat
    18361 taaagtagac ttaaaccagt attttggata atttttttcc agaccttgtc acttcaataa
    18421 atataaacct gccttctatc aaccaatcaa tctcctacaa caaaaaaaca ccccaaggtg
    18481 tactgccccc aaaaagttga acgaataatt attgaaagga tttagttctg tattgaacag
    18541 ggctaagtcc ttttagttta gttttgattc gtttattgtt gtagtaaaag atgtattcag
    18601 tgattgcttg ttcgagctca tccagtgagt ggtaggattt ctcaaagcca tagaacatct
    18661 ctgactttaa aatgccaaag aaggattcca
//
LOCUS       DARYLJ010000043        18175 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYLJ010000043 DARYLJ010000000
VERSION     DARYLJ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18175
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            62..298
                     /locus_tag="TU746_001508"
     CDS             62..298
                     /locus_tag="TU746_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL0891830.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            362..1633
                     /gene="murA"
                     /locus_tag="TU746_001509"
     CDS             362..1633
                     /gene="murA"
                     /locus_tag="TU746_001509"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL0891831.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1637..1825
                     /locus_tag="TU746_001510"
     CDS             1637..1825
                     /locus_tag="TU746_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL0891832.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1857..2735
                     /locus_tag="TU746_001511"
     CDS             1857..2735
                     /locus_tag="TU746_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0891833.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2749..2907
                     /locus_tag="TU746_001512"
     CDS             2749..2907
                     /locus_tag="TU746_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891834.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3647..4690
                     /gene="pheS"
                     /locus_tag="TU746_001513"
     CDS             3647..4690
                     /gene="pheS"
                     /locus_tag="TU746_001513"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL0891835.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4880..7285
                     /locus_tag="TU746_001514"
     CDS             4880..7285
                     /locus_tag="TU746_001514"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL0891836.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVETVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7520..8596
                     /locus_tag="TU746_001515"
     CDS             7520..8596
                     /locus_tag="TU746_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891837.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8606..9310
                     /locus_tag="TU746_001516"
     CDS             8606..9310
                     /locus_tag="TU746_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891838.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
     gene            9649..10773
                     /locus_tag="TU746_001517"
     CDS             9649..10773
                     /locus_tag="TU746_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL0891839.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(10935..11528)
                     /locus_tag="TU746_001518"
                     /pseudo
     CDS             complement(10935..11528)
                     /locus_tag="TU746_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622734.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            11597..13570
                     /locus_tag="TU746_001519"
     CDS             11597..13570
                     /locus_tag="TU746_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL0891840.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
     gene            13594..15036
                     /locus_tag="TU746_001520"
     CDS             13594..15036
                     /locus_tag="TU746_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL0891841.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            15117..15926
                     /locus_tag="TU746_001521"
     CDS             15117..15926
                     /locus_tag="TU746_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL0891842.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            16238..17395
                     /locus_tag="TU746_001522"
     CDS             16238..17395
                     /locus_tag="TU746_001522"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678097.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL0891843.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVV
                     EVWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHE
                     FRKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINR
                     FLSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL
                     LDAYINGYGYIHKFAKNTPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSE
                     ALYTGKAIGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERV
                     GLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            17481..>18175
                     /locus_tag="TU746_001523"
     CDS             17481..>18175
                     /locus_tag="TU746_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0891844.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
BASE COUNT         5633 a         3659 c         4096 g         4787 t
ORIGIN      
        1 taattattcg tccaactttt tgggggcagt acatttgtta gacttttgat ataataaagc
       61 tatggaagta attagaactc ttttaatgtt tttcagccat ttattattta ttggcattag
      121 ttatcagcta ctcattagcc tagttgattg gtcaaaattc attcattacc gaccagagaa
      181 tatgggaagg cttcgcttgc ttgtcctttt tttggcaatt gcctcaggct atttagttag
      241 tcgctttatg ctggaattaa ttcaaatcag tcagtatctg ctgtatgatt tccactagag
      301 taggcagtca ggaagtatga tataatatta gtacgatgac cagtaggaaa tggagaagct
      361 tgtggataaa ataatcatag aaggtgggag cacacgttta gagggagagg taacgatcga
      421 aggcgctaaa aatgccgttc ttcctttact agcagctact atcctcccct caactggaaa
      481 gactgtcttg agaaatgtgc cgattctctc agatgttttt acgatgaact atgttgtgcg
      541 tggcctaaat attgacgtcg actttgatga ggctgccaac cagattacag ttgatgcctc
      601 aggggacatt ttagatgttg ccccgtacga gtatgtcagc caaatgcgcg cctcaattgt
      661 ggttttaggc ccgattttag ctcgtaatgg ccatgccaag gtatcgatgc ctggaggctg
      721 tacgattggc agtaggccga tcgatttgca tttaaagggc ctagaggcta tgggcgctga
      781 gatcacccag cagggtggtg acatcactgc aaaggctgag cgcctaaagg gggcaatgat
      841 ctatatggat ttcccatcag tgggggctac gcaaaatttg atgatggcag cgacccttgc
      901 tgatggtgtg acagtcattg agaatgctgc tcgcgagcct gagattgttg acctagccca
      961 gctgctcaac aaaatggggg ctaaggttcg tggggcaggt accgaaaccc tgaccataac
     1021 gggtgtcacc agtctatgtg gggttgagca tgatgttgtt caggatcgta tcgaagcagg
     1081 tacctttatg attgctgcag caatgacctc cggtaatgtg ctgattagag atgctgtatg
     1141 ggagcataat cggcccttga tttctaagct catggaaatg ggagtgtctg ttgtcgaaga
     1201 ggatgcaggc attagggtgc aggctgatgt gactaaacta aggcctgtca ctgttaaaac
     1261 tcttcctcac ccaggctttc caacagatat gcaggctcag tttacagccc ttatggccat
     1321 tgttaaggga gaatctacga tggtggaaac agtctttgaa aatcgtttcc agcacctaga
     1381 agaaatgcga cgcatgggct tacaatctga ggtattgcgt gatacagcta tgattcatgg
     1441 tggtcacgaa ttacagggag cgcctgtgat gtcaacagac ctgcgagcta gtgcagccct
     1501 catcttaacg ggaatggttg ccaaaggcag gaccactgtg aataaattga accatttaga
     1561 tcgtggctat tatcagtttc atgaaaagct tgccaagcta ggtgccaaca ttcagcgaat
     1621 tagtgaggag tagtcaatga ctaatggttg gagatatgtc ataaatcagc taatgctaat
     1681 catagctatt ggactgctcg gactcttttg tctggcgctg ggactaatga ttggctatag
     1741 ccttatcggt gatggccaaa atcctttagc gattttatcg ccagataagt gggctgagct
     1801 gattcataaa tttacgggaa agtaggcatg gcctgctttt tatgataaga ggaaagatga
     1861 tcaaaaagaa gaaagacatc aggctgctta atgccttttt agcgctcttg cttgttcttg
     1921 gaacaggtta tttggcagga catgatgacc tagcagctga taacccgatc aagcaggtct
     1981 accaaaggat tcttggctct gacacgcagc aagccgggct accaaaggca agccgagact
     2041 gggacactcc ctccaaggcc ttggcagatt cggtcatgac agccaccatc aaacagcaat
     2101 taggtgatgt gattacttgg aatggcactg gtgcctatat cattaaccat aataaaacga
     2161 cgctaaatgc aaaggtagct agtctcccct atgccaataa taaaacaaag atggtacaag
     2221 ggcaaagcgt tcctaccgta gccaatgccc tgctaaccaa gtcaacccga caatatcaga
     2281 agcgcaatga cactggaaat ggctatagct catggaagcc tgctggctgg catcaggttc
     2341 aggggttaaa gggaaggtat agtcacgcag tggatagagg gcatcttcta ggctatgcgc
     2401 ttgttggcgg gctaaaaggc tttgatgcct caatggctaa tcctagtaat atcgctactc
     2461 aaaccgcatg ggctaaccaa gcagctaacg agagatcaac cggacaaaac tattatgaaa
     2521 caaaaattcg caaagcccta gatagcaata agcgtgtccg ctatcgtgta actttgcttt
     2581 atgagggaaa taatctctta gcaagcggca gtcatcttga ggcaaagtca tcagatggta
     2641 gcttagaatt taacgtcttt atccctaatg tacaggctgg attacagatt gattatcaaa
     2701 caggtcagat cactgtagct tcttcccagc cttagtgagg cacatcacat ggcaaaagct
     2761 gatcacgtag ctagccatca tggcagagaa gcattagtcc ttgtagtccc tcaaagaaag
     2821 gtgctaacaa tatttggtct tgtggcttta gtagaaaaac agataggtcc tttagtcgaa
     2881 gcaccaagca tgccagctcc tgattaggac aaatgtcaag gctaagcggt ggtaagttaa
     2941 agtctcacaa aagacaagac tggacttttg gctatagtcc tttatgactg atgccagctg
     3001 ataatggctc aagatgattg aggtttctag caatgcttgt ggctagccta tcgtcttagt
     3061 tagcgctgat tgatgagatg ttgaacagtt cttgactaaa agcatcccta cccttacgcc
     3121 tacgtcctgg ttagtgaaga aataagcatt gtcataaagg catttttttg atacaataaa
     3181 agtaattgaa tagcagtcta tgagactagt actaataggg aagttaatag ggaatggggg
     3241 tcgtgactgg aagccttctt aatgaaacga ttaggaattc actcaatcaa ggacgaggta
     3301 attaaggtct gacttgctca gatgaaaacg gatggtaccg cgtgtcaacg ctccgcttta
     3361 gataggagcc ttgatacgcc ttttttgatg acgtgctgtt actattagct atttaatcac
     3421 aagcaagcac tagccagcca aaagtaagtg atcactataa gcatagaaag ataggagctg
     3481 tagcttatct agaaaagcaa gggtgatcag tcgtccgccc aaaagtcttt cttagctttt
     3541 gtgatgtgac tagctgacct agctgctcac agcttagcct aaaaggccta ttagcacaag
     3601 gactgccagc attaatgcaa tcattttcca aacagaaggg aatatcatgg atttacaagc
     3661 acaattagaa gaactgaaaa ccaagacaca agaagcgctc aagcagctaa atggtgacca
     3721 cagcaaggaa ttacaggagc tgcgggttgc tgtccttggg aaaaaaggaa cgcttaccga
     3781 actgctcaag ggactaaagg atctctcaaa tgacctgcgt cctgttgttg gcaaacaggt
     3841 caatgagctt cgtgactttt tgacccaagc ctttgaagag caggctaagg tggttgaggc
     3901 agcaaagatt caggccaagc tagattctga aagcattgat gtgactttgc caggccgtca
     3961 gatgaagcag ggctatcgac atgtgctcac tcaaatcagt gaagaaattg aggacatttt
     4021 cttgggcatg ggctttcaaa ttgttgatgg ctttgaggtt gaaaaggatt attataattt
     4081 tgaacgcatg aaccttccaa aggatcatcc ggctcgtgat atgcaagaca ccttctatat
     4141 cacagaggat attttgctgc gcacccacac cagtcctgta caggcacgaa cactggacca
     4201 gcatgatttt tcaaaggggc ctctcaagat gatttcacct ggacgtgttt tccgtcgtga
     4261 caccgatgat gccactcatt ctcatcaatt tcaccaaatt gaaggcttag tcgttggtaa
     4321 gtctatttct atgggagact tgaaggggac tcttgagatg atcattaaaa agatgtttgg
     4381 taaggagcgt aagattcgcc tgcgcccatc ctatttccct tttactgagc catctgttga
     4441 ggttgatgtc tcatgcttca aatgtggtgg taaaggctgc aatgtctgca aaaaaacagg
     4501 ctggattgaa attcttggag ctggtatggt gcacccaagc gttttagaaa tgtcaggtgt
     4561 gaatgcgcag gagtattcag gctttgcctt tgggcttggt caagagcgca tcgccatgct
     4621 gcgctatggt atcaacgata ttcgaggctt ctaccaagga gatagtcgct tttctaagca
     4681 gtttaagtaa tagtgatcat atggtcaaaa accaaatcat cagtttgaaa aaagaactga
     4741 cgctcaatct ggagctgttc tttggattag aatcagaaag gaaaaagacg ggtaaagagc
     4801 aaagaagtga ttggctagct tatctcaagc aggtgctagg cagatctctc atcagcgctc
     4861 actactctat tgaaggctta tgttagtatc ttataaatgg ttgaaaaaat tagttgacat
     4921 tgatgtctca ccggccgagc tagctgaaaa aatgtcaaca acaggtatcg aagtagaagg
     4981 catcaccagc ccctctgaag gtttatcaaa gctagttgtt gggcatattg tctcatgtga
     5041 cgctgttcca gaaacgcacc tgcacctttg tcaggtcaac acaggagatg atgagcttcg
     5101 tcaaattgtc tgcggtgcac ctaatgtcaa agcagggatt aatgtgattg ttgcgctgcc
     5161 tggagctcgt attgcagaca attacaagat taaaaagggt aaaatacgcg gtatggagtc
     5221 tcttggcatg atctgctcac ttcaggagct tggcttacca gatgcgatta ttccaaaaga
     5281 tttttcagaa ggtatccaga tcctaccgga aacagcagca gcaggtgata gcattttccc
     5341 ttaccttgat ttagatgaca atatcattga gctttccatc acacctaatc gtgctgatgc
     5401 cttatcaatg cgtggtgttg cccatgaggt ggcagctatc tatggcaagt cagtgtcatt
     5461 tccagaaaag ccccttatcg aatccgctaa agcagcagct gatagtctag aggttgctat
     5521 tgactctgac aaggtgctga cctatgctag tcgtattgtt gaaactgtca ccgtcaagcc
     5581 aagtccgcaa tggctgcaaa atcttctgat gaacgctggc attcgtccaa tcaacaatgt
     5641 tgttgatgtg accaattatg tcttgctgta ttttggtcag ccaatgcatg cctttgatta
     5701 tgataccttt gctgatcata agcttttagc gcgtgatgcg cgtgagggag aaaggcttgt
     5761 cacccttgat ggagaagagc gtgtgctaac cacagatgac attgttatta ccgtagcaga
     5821 ccagccagtg gctctagctg gtattatggg aggcaaatca acagaaatca ccgcctcctc
     5881 aaagacagtg gtgcttgaag cagcagtctt taatggcaaa tcaatccgta aaacaagcag
     5941 tcggctaagt cttcgttcag aaagctcatc acgctttgaa aaagggatta accatgacac
     6001 gcttgtagag gccttagatt ttgcggcagc catgctagaa gagctagccg gtgggactgt
     6061 tttagcaggg cgcttgcagg caggctcact gcctaccaat ccggtagagg tttcaaccag
     6121 ccttgattac gtcaatgtcc gcttgggaac agccttgagc tttactgata ttgaggggat
     6181 ttttgcaagg cttggctttg gtattagcgg aactgctgaa cactttaccg tttcagtgcc
     6241 acgacgccgg tgggatataa caattccggc tgacctagtc gaagaaattg cccgtatcta
     6301 tggctatgat cgattgccaa ccacattacc agaagctgct ggcacagccg cagaattaac
     6361 caaaacacag gcccttcgtc gtcagctgcg tggtcttgca gagggactgg gtttaacaga
     6421 aatcatttcc tatgctctaa caacacctga aaaggccctt gaatttgcaa tgaagccaag
     6481 ccagttaaca gagctgatgt ggccaatgtc agtcgagcgc tctgtccttc gtcaaagcat
     6541 ggtatcaggt atgcttgaca cccttgccta caatgtggca cgtcaacagc ataaccttgc
     6601 cgtttatgag attggtaagg tctttgagca agagggcaat cccaaggaga cattaccaac
     6661 agagcttaat cactttgcct ttgctatcac aggcttagta gcagacaagg attttcagac
     6721 acaagcgcaa gcggttgatt tttaccatac taagggaatc ctagagtgtc tctttgataa
     6781 gctaggactg tctgtggatt atatcccaac aaaggagatg gcgagcatgc acccaggacg
     6841 taccgcacgt attcagctag gagatcaagt gattggcttt gttggtcagg tgcacccaca
     6901 ggctgctaag gcttatcata tcccagagac ctatgttgca gagcttgacc tgactgctat
     6961 agaggcagct ctaccagctc atcatgcctt tgtggaaatc accaaatacc cagctatggt
     7021 aagggatatt gccttattgg ttgatgcctc aaccagtcat caagccattc tttcagcgat
     7081 cacgtctgcc aaggtaaagc gtctaacaga gattaagctc tttgacattt acgcaggagc
     7141 aattattgcg gccggtaaaa aatcaatggc ctatagcctg accttccaaa atccaacaga
     7201 caatctgact gatgaggagg ttgccggcta catggagaaa atcaccaagg ccttggtaga
     7261 aaaggttggt gcagaggtga gataaggacg cttctaatga ctagctacct aaaaaaagct
     7321 catttcaaag gcttagctgc aattgttctg ttgcggctga gctttttttg atgcttagac
     7381 tgtccttatc ctatgctagt tgcagcaagg gtttagagat gattttattt aaattatcag
     7441 tcaaaaatat tttttctaat caaattccta gctttatctg atctcctctg ctatactgtg
     7501 caataagtaa ggagattata tgtttttagc cctaaatgaa ataaaacaag ctaagctcag
     7561 atatggcttg attatgggac tgctctgttt agtagcctat ttgatgttct ttttatccgg
     7621 tttagccttt ggattaatgc aggaaaatcg ctcggcagtt gacagctggc aggcagatac
     7681 agttcttttg tcaaaggacg ctgacgccaa tctcagccta tcctctttaa agaccagtca
     7741 gcttaaggag atcaaggctg atgaggtcac tcccctagcc cagctgaata cagttgcttg
     7801 gtcaacccaa gctccaacag aagaagacaa agaaaaaatc agcttttttg gcattgagag
     7861 agagtccttt ctcaagccta caatcacaaa aggaaggcta tttaagtcag acaaagaggt
     7921 ggtgattgat caaagccttg ctgagaaagg aggctttaag cttggagatc agctgcgggt
     7981 atcggcctct aaccagacct ataccatcgt tggctatacc aagaatgcta gctttaacgt
     8041 gtcacctgtt gcttacctca acctgacagc ctttcagggc ttactgtatg gtcaagaagc
     8101 aggcgcacaa gacccaaatg ttaatgcctt tattatcaaa ggcaagctag ctgactatcc
     8161 caaggaagag cttcagcagc taacgattgg cgacttcatc aacaagctgc cgggctatag
     8221 tgcacagctc ttgacctttg gctttatgat tgggttttta gtgttaatct cagccattat
     8281 cattggtatt tttatgtatg tgctgaccat tcaaaaggca ccaatctttg gtatcatgaa
     8341 ggcacaaggc attgctaatc gtaccattgc aaatgctgtg ctatcacaaa cctttgtcct
     8401 aagccttttg ggcagcagcc ttggcctact aggcacctgg ctaagctcgc ttgtcttacc
     8461 agcaacagtt ccctttcaga gcaattggta cctatatgcg cttattttag ttgctatggt
     8521 agtctttgca gtattaggca ccctcttttc agtctttacg attgttagaa ttgaccctct
     8581 agaggccatt ggttaggaga agaatatgac agtattagca tttaagcagg tcacaaagtc
     8641 ctttaaggac ggtgatcaga ccattgaagc cctgaaaaag acggattttg cgattaaagc
     8701 aggcgagttt gtcgccctta taggtccatc aggctcaggc aaatcaacct ttctgaccat
     8761 tgcaggtggt ctacaaacac caagctcagg acaattttta gtcaatggca aggattacac
     8821 caacctatct gaaaaggaac gatcaaaact acgctttaag gacattggct ttatcctgca
     8881 ggcttctaat ttgattccat ttttaaccgt caaacagcag ctagaattag ttgacaagtt
     8941 gaccaagcac aagcaggaag caaagcgtca gcagctcttt gaggacttgg gaatcgctaa
     9001 gctggctaat aagctgcccc aagatttatc cggtggcgag cgtcagcgtg ttgccattgc
     9061 cagagcccta taccatgatc ctgtgatcat tttagcagat gagccgactg ccagtctgga
     9121 tactgaaaag gcctttgagg tcgttgaact tctagctaaa gaaagcaagg aaaaaaacaa
     9181 ggcaattatc atggtaaccc atgataaccg tatgattgac tattgcgata aggtctatcg
     9241 catgcaggac ggccaattga gtcaagacaa tcatcatata gctagcaatg ccgcaatgac
     9301 tcaaaactaa tcgaatagga aaagctctgc tctagcgata tagcagggct ttttagctgc
     9361 tctaaattat ctcaaaagtt ccttttactg atatttaata ttttctgtat ttttaattta
     9421 tagaaaaata aagaaacatg ctgagagttg atcaaaacac ttactatact tacgatgaca
     9481 agtaacttgc taaagtaatg gttgacatat aattgtaaaa aaacagaaat aaaaaaaaaa
     9541 cggtttaata ttgacctaat tggcaataac gtttacaata aaggtataat tatctgccgt
     9601 tgataattag gagacatcat gtctagataa aaacaaaagg ggaataaaat ggcaaaaaaa
     9661 gaaatgaagt tttaccttcg taaatcagcc tttgggctag cttcagtatc agcagccctc
     9721 ttggttggtg cggcagctgt atcagcagat tctgttgagt cagctgggcc tgtagcagtt
     9781 gctgttacag atagtttaga tagtgaagcc gcagctacaa aggcagaagc tgatctagtt
     9841 gctgcaaaag cagacctagc agcagcagaa gtagcaatca cagctgcaaa agctgaattt
     9901 gacaccgctc aagcagacct agctaccgct gaagctacta tcgcagagct tgagcaaaaa
     9961 attcctgagt tagagaaaaa aattcaagaa gctcaggaaa aactaaacta tgaaaatcga
    10021 ccatcaccta aacgtgtggg cagtgatgat gaagatgaca cagtagctag aaagcttatg
    10081 tcagaaaagg aagctcttaa ggctgagctt caaaagacta aagaagcgct agatacagct
    10141 aaaagagctt atgctggcat cgaagaaaga aaacaagtag cagcaactaa gctagatgca
    10201 gctaacaagg cttttgctgg agttgaagaa aagcatgctc aagcaatggc tgcatttgga
    10261 gcagcattcg cagcatacaa ggaagctgtt aaggctgaat tgaaggcagc aggtgctagc
    10321 gacttctaca ccaagaagat tgactctgcc gacacagttg acggtgttaa gacactcaga
    10381 gaaatgatct tagactcaat tgctaagcca gaggttgaac cagaggctaa gcctgaacct
    10441 aagccagaac caaaacctga gccaaaacct gagccaaaac cagaacctaa gccagaacca
    10501 aaacctgagc ctaagccaga gccaaaacca gaacctaagc ctgagcctaa gccagaacca
    10561 aaaccagaac ctaagccaaa acctcaacct aaaccagctc cagctccaaa acctgaagct
    10621 aagaaggaag agaagaaagc agcgcctaag caagacacca acaaattgcc atcaacaggt
    10681 gaagctacaa atccattctt caccgcggca gctcttgcag ttatggcagg tgcaggcgtg
    10741 gctgcagtgt caacaagacg caaagaaaac taagccttat accccagtgg taaagcttga
    10801 gcgagaacaa tttgttctcg cttttttagt gtcttaaaag cacctacagc aatcataggt
    10861 gcttaacaag atatgtctaa cgattgctat cagctgtaga gaataaaaag gagagactaa
    10921 gccttgctca caagctactt agaccgaagg agctttagga tttctatgat ttgctgaggg
    10981 gagtccttac agccgcagct gatccactta atgatgatga cctcaataga ggcaatgtat
    11041 agctcaaaaa catatttttg ggtaacttca ggataatctt gtgattctgc acaattcatg
    11101 aggttggaat aggaaataat atccctaata taatgattaa aaattttata aatattagga
    11161 taataaagga ttaagctttg catgacctcc tgattgtcag agaggtagtt taggattttt
    11221 aaggtaatag ttgtatcaag tgatggggat tggtaaatga tagaggtgat atcatctagg
    11281 taaacgccga tcatttccct atctaagtcc ttcttagagt tgaaataatg ttaaaaggtt
    11341 gttcgactga tattagaagc cttgctaata tctgatacag taatactgtc cttatccttg
    11401 tattgtagta gtcggcagta gcttttaatt atttttttac aagtttgttt atttttatcc
    11461 attgtatcat taactcctta aaattgaaca ttaatgttaa ttttgtacat aatatttttt
    11521 gctaacatta tacaatgatg aacgtgattt gtaaaattaa attttgcaaa tcaataatgt
    11581 aaaaggagga ttttgtttga aacaactgac aaagatcgtt agtgtggtct tgttgctggt
    11641 ctttaccctt agtgctagcc tgcacaaggt tcgggcaact aatcttagtg acaacatcac
    11701 atcattgacg gttgcttctt catcactccg agatggagag agaacgacgg taaaggttgc
    11761 gtttgatgac aaaaaacaga aaatcaaggc aggggatacg atagaggtca cctggcctac
    11821 aagtggtaat gtctacattc agggctttaa taaaaccata ccgcttaata ttagaggggt
    11881 agatgttggt accttggagg tcacgctaga caaggctgtt ttcacattca atcaaaatat
    11941 tgaaacaatg catgatgtct ctggttgggg agagtttgat attactgtta gaaatgtgac
    12001 acaaaccacc gctgaaacat caggaacgac cacagtaaag gtaggcaatc gcactgctac
    12061 tatcactgtt actaagcctg aggcaggcac tggtaccagc tcattttatt ataagactgg
    12121 tgatatgcag cccaatgata ctgagcgtgt gagatggttc ctgctgatta acaacaacaa
    12181 ggaatgggtg gccaatactg ttacagtcga agacgatatt caaggtggtc aaaccttgga
    12241 tatgagcagc tttgacatca ccgtatctgg ttatcgtaac gagcgcttcg ttggggaaaa
    12301 cgctctgaca gagtttcata caacatttcc aaattctgtc attacggcaa cagataatca
    12361 cattagtgtg cggttagatc aatatgatgc ctcacaaaac actgtcaaca ttgcttataa
    12421 gacaaagata acggactttg accaaaaaga atttgccaac aacagtaaaa tctggtacca
    12481 gattttatac aaggatcagg tatcgggtca agagtcaaac caccaagtag ccaatatcaa
    12541 tgctaacggc ggggttgatg gcagtcgcta taccagcttt actgtcaaga aaatttggaa
    12601 tgacaaggaa aatcaagacg gtaagcgtcc aaagactatt actgttcagc tttacgccaa
    12661 tgatcagaaa gttaatgata agaccattga attgagtgat actaatagct ggcaagcaag
    12721 ttttggtaag ctggataagt atgacagtca gaaccaaaaa attacctaca gtgtcaagga
    12781 agtgatggtt cctgttggct accaatcgca ggttgagggg gatagtggag taggatttac
    12841 cattaccaac acctatacac cagaggtcat tagcattacc ggtcaaaaaa cttgggacga
    12901 cagggaaaac caagacggta aacgtcctaa ggagattacg gttcgtttat tggcaaatga
    12961 cgctgcaact gacaaggtag caactgcttc agagcaaacc ggctggaagt atacatttac
    13021 caatctaccg aaatacaaag atggtaaaca gatcacctac acgatccaag aggaccctgt
    13081 ggcagattac accacaacca ttcagggatt tgatattacc aatcatcatg aggtagcctt
    13141 gaccagccta aaggtcatca aggtttggaa tgataaggac gattattacc ataaacgtcc
    13201 caaggagatt accattttgc taaaggcaga tggcaaggtg attcgtgaac atcagatgac
    13261 accggatcag caaggaaaat gggaatacac ctttgaccag ctgccggtct atcaggcagg
    13321 caagaaaatc agctacagca ttgaggaaaa acaggttgct ggctatcaag cccctgtcta
    13381 tgaggttgat gaaggcttga agcaggtcac tgtaaccaac acccttaacc caagctacaa
    13441 gctgcctgac accggaggac aaggagtgaa atggtacctg ttaatcggtg gcggttttat
    13501 catcgtcgca atccttgtac tgatcagcct ttatcaaaaa cacaagcgcc ataacatgtc
    13561 aaaaccataa catgtaatag aggagagaga gctatgaaaa caatcaaatt aatcttgacg
    13621 agcttgcttg tcaccttcct aacaatgctg tcaggaaagg catttgctga tacagcaagc
    13681 tataccatca ctgttgaggg agctacagca ggtcacacct atgaggctta tcagattttc
    13741 aagggtgact tgtttgacag taccctatca aacatcacat ggggaggtgg tgttacacct
    13801 tttgaatttg atggttcaaa agacgctgct aagattgcag agggattgaa ggaagcaaat
    13861 gcagctgcct ttgccaagga agcaggtaag cacttgacag caaccattgc aggaacagga
    13921 acacatgcaa tcaccgttaa cgaggctggc tactacctca tcaaggacaa aaatgattct
    13981 caaacaggca agcatgacgc ctacacctca tttgtcctga aggttgttaa aaacaccagc
    14041 ttcaaaccaa aatctgctat cccaacagtc cttaaaaagg tcaaggaccg taatgacaag
    14101 acaggtcttg agacaggctg gcaagattca gctgactatg acaaaaatga caaggtgcca
    14161 ttccagctaa ccgcaaccct accgtcaaat tacgatgcct ttcaagaata ctaccttgaa
    14221 tttgtagata ccttatcaaa agggctaagc tacaacaaag acgccaaggt ctatgtggtt
    14281 aatggagata ctcgtcaaga tattactaat tcatttacag ttagtgaaga tggttcatct
    14341 tttaaaatca ataacctaaa ggctgttcag ggagtaacaa taacagctac cagtaagatc
    14401 gttgtcgaat acactgctac cctcaatgac caagcggcca tcggcaaaaa aggaaatcca
    14461 aacgaagttg ctttgaaata ctcaaacgat ccaaacgctc ttggaaaagg agaggagtct
    14521 ccaaaagggg agacaccaaa agacaaggtt atcgttttca cctataaaac tatcatcaat
    14581 aaggttgatc aagatcaaaa agccctaaaa ggtgcaggct ttacccttta taagctggtc
    14641 aaaggtgata atggcgagga aaaatatcaa atagtccaag aaattaaagc aggggataca
    14701 actagctttg agtttgttgg acttgacgct ggtgattaca agctcagcga aacaacaaca
    14761 cctggcggtt acaacactat tgcagatgtc atgttcagca ttgtagcgca gcatgaaacc
    14821 gagtcagacg atcctcagtt gactagccta accgttgaca aagcaactgg cttcactgct
    14881 gatacagaag ctggtaccgt atccgcaact attgttaata aaaaagggtc tatcctccct
    14941 tcgacaggaa gtatcggaac aaccatgctc tatgtgtttg gagtaatgct aatgacaata
    15001 tcaacgctgt ttatctttcg tcagaaacag caataagatc gtgtgagtag gtaaaaagaa
    15061 gtggatagac gtcttaccaa gacctattca cctctttttt tgatagaggc tatagaatga
    15121 agaaaagtgt cattttttgg agtgtgattt tggtggcagg ctgtctgatt gtcctttacc
    15181 ccacccttag taactattgg aatgcacagc accaatcaca gctcatcgct gactatgtct
    15241 caagcacgca agctttgaga cataaggata gtcagctcat gctagaagca gccaatcagt
    15301 acaatcagca gctaaaagct aaccatgatc ctgatttaac cttgaccgat agtgaggcag
    15361 aagcctatca gcagcagctg gatctgacaa atacaggtat catggcctac atagatattc
    15421 caaaggtgca tgagcggctg ccgatttatc atggcaccga tgaggagatc ctacaggtgg
    15481 ctatcggtca tcttgcaggc acctctttgc ctgtaggtgg caagggaaca catgctgtca
    15541 tctcaggaca tcgagggtta ccctctgcca agctatttac caatattgat aagctgagga
    15601 ttaacgatac ctttaccatc accagtctta ataggactat gacctatcag gtggataaga
    15661 ttgctaccgt tttgcctgat gatgtcagcc tcttaaggat agaggagggg aaggatctgg
    15721 taaccttggt cacctgtacc ccctacggtg tcaacacgca tcggctcttg gtcagagggc
    15781 atcgtatcaa aacagcgaca ccaaccgctg caagaggatc tcaaaagcct agtaggctaa
    15841 tcctctggct cttgctaatc agtgcattag ggctatctct cgtactaata ggcacttggc
    15901 gctggcgtag gaggtctaaa gcatgagcag gctttccaga agcaactaag tcaaatcatc
    15961 aacccttgat aggttactga ggacctatca ggggattttt tagtgctaaa ttgcgactat
    16021 gattaaaaac acagaaatcg tttttttttc ttagtgaccg aaaacgcttt aaaagagcga
    16081 gcatttggag ccttcaaaag tgacatctga gcataacatg ataaaattga cttataaaac
    16141 ctaataaaat gataaaagga ggagagttaa cgacaaaata ttagatattt atttaatttg
    16201 ttgtttttga aaacgtttta taataagaaa ggatagcatg atgaaaaaac aatcattcac
    16261 acactcacgt aaacctaaat tcggtatgag aaaattatct attggccttg cctcatgtat
    16321 gctaggaatg atgttcctaa caacaggaca tgtttctggt gaggtagttg aagtttggcc
    16381 taatgggcaa aatcctaatg gtaaaataga aattctaagt caaactgagc actctgagca
    16441 tttacagaaa ttacgcgata ttgaagattt ccaagctcaa aagcaagctg atcatgttcg
    16501 ttacactaaa tggttagatg gggtaactgt tgatgagcat gaattcagaa aaatcaagga
    16561 atatgacaca gaatattatg taacacctct tttaagtggt aaaggttact atgatatcaa
    16621 taaagatttc aatcaagata gtgataaatg tgctgccgct gtagcggcta atatgttcca
    16681 ttattggttt gatagaaata gagacagtat taatcgtttc ttaagtcaaa gtccaggtga
    16741 aaatggtgtt attaaacttg aaaatgaaaa aacaatagaa gtatcaaaat ttttagaaac
    16801 ttaccgtagt gatggtgatt atcttgataa aagtccgttt tttgacctta tcagtaacag
    16861 ctttaaaggt cctgtttggg caaataagct attggatgct tacattaacg gctatggtta
    16921 tatccataaa tttgctaaaa atactccaca ttctaaaaat aataatagta aatttaattt
    16981 ctttaaaaaa gtatttgatg gtaatctctt gacagatatt caccaaattt ttgattataa
    17041 cactttttca gataaattaa gtgaggctct ctatactggt aaagccattg gattggccta
    17101 cggacctgga gacttgcgtc gttcactagg tcatattatt tctgtctggg gagctgatct
    17161 tgacgatcag aatcgcgtgg tagctattta tgtaactgat tctgatgata aaaagttaac
    17221 tataggaaat gagagagttg gtttgaagcg atataaagta tctagcgatg atcaaggtcg
    17281 tgctcgtctg acgactcgtg ataaagataa cacaggtggt gaaattcgat ctattgaaac
    17341 attagatatg ggtacacaag agtgggcaga ttacttcaac aagacagaaa aataacaata
    17401 acccctacac atatatgatt actccagata aagcacacag caatagactc agccagtaag
    17461 gaaaggacga taacaaaacg atgctaacaa accaaacggg gtacaggcat agacttagta
    17521 agcagaagct acctatcagc atggtttcct gcttgctagg aatgggggtg ctaacctctc
    17581 caacattaat ctcagctgat gatagttctc ctactatcat cattaaatcg ggtgcaggta
    17641 tgacaattga tcctcaatta ccgaaaactc tcctttctaa acccgaagag aaaccagagg
    17701 aaacacctaa acttccagat gagcgacatt atggtgatga tgtcagaccg gaagaaacac
    17761 caaagcttcc agacgagaga cattatggtg acgatataaa accggaagag atgccaaagc
    17821 tcccagatga gcgacattat ggtgatgaca tcaggaagcc gaaaccggag gatactccaa
    17881 agccacctaa tgaaagcggt caaggtaatg acttaaaaga agatttggag cttaaaaagc
    17941 aacgtcgaga gcttacagag cagcttcgtg ctttaaaaac tattgaggaa gttttagagt
    18001 tcctgagaaa accaattcct ggatttgtaa cagatgaaga ttggaatttc ttagtatcat
    18061 ttgtagaaaa aggcccagaa aataaaactt ttgaagtaga taaattaaaa ttactagaaa
    18121 tcttctcaac ctcacaaggt catagagttt ggttaggtta ccttattctg gaaga
//
LOCUS       DARYLJ010000044        15905 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYLJ010000044 DARYLJ010000000
VERSION     DARYLJ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15905
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(93..563)
                     /locus_tag="TU746_001524"
     CDS             complement(93..563)
                     /locus_tag="TU746_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL0891845.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            784..1634
                     /locus_tag="TU746_001525"
                     /pseudo
     CDS             784..1634
                     /locus_tag="TU746_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1970..2260
                     /locus_tag="TU746_001526"
     CDS             1970..2260
                     /locus_tag="TU746_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL0891846.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            2274..3413
                     /locus_tag="TU746_001527"
     CDS             2274..3413
                     /locus_tag="TU746_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891847.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            3410..3892
                     /locus_tag="TU746_001528"
     CDS             3410..3892
                     /locus_tag="TU746_001528"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL0891848.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            3889..4476
                     /locus_tag="TU746_001529"
     CDS             3889..4476
                     /locus_tag="TU746_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0891849.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            4473..4955
                     /locus_tag="TU746_001530"
     CDS             4473..4955
                     /locus_tag="TU746_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891850.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4980..5495
                     /locus_tag="TU746_001531"
     CDS             4980..5495
                     /locus_tag="TU746_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891851.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            6129..7763
                     /locus_tag="TU746_001532"
     CDS             6129..7763
                     /locus_tag="TU746_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891852.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7904..8797)
                     /locus_tag="TU746_001533"
     CDS             complement(7904..8797)
                     /locus_tag="TU746_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0891853.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8781..8972)
                     /locus_tag="TU746_001534"
     CDS             complement(8781..8972)
                     /locus_tag="TU746_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891854.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9207..10961
                     /locus_tag="TU746_001535"
     CDS             9207..10961
                     /locus_tag="TU746_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL0891855.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            11102..11482
                     /locus_tag="TU746_001536"
     CDS             11102..11482
                     /locus_tag="TU746_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL0891856.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            11520..13853
                     /locus_tag="TU746_001537"
     CDS             11520..13853
                     /locus_tag="TU746_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0891857.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13902..14054
                     /gene="rpmG"
                     /locus_tag="TU746_001538"
     CDS             13902..14054
                     /gene="rpmG"
                     /locus_tag="TU746_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0891858.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            14066..14242
                     /gene="secE"
                     /locus_tag="TU746_001539"
     CDS             14066..14242
                     /gene="secE"
                     /locus_tag="TU746_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL0891859.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14633..15178
                     /gene="nusG"
                     /locus_tag="TU746_001540"
     CDS             14633..15178
                     /gene="nusG"
                     /locus_tag="TU746_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL0891860.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
BASE COUNT         4572 a         2904 c         3515 g         4914 t
ORIGIN      
        1 atcaaggctt ttgcaggaga tttatgaaaa agaaaaattt aggatagtgt aagtataagc
       61 tagtttcctt aagaaaagct taactgaagc aattaatcgt agagatgggt gattgttttg
      121 acgacttttt tctccttgtc agaccaataa tgaaggcgtt caaaagatcc ttgtcgccag
      181 tagagtggta gcctttgtcg aatatcctct tgcatgtcta gcttatctag atcagcaata
      241 gcatgccatt gtggtaggcc ctctcgtgat ttagttagca gcttgccttc aaaatcttcg
      301 caaagaaagt cataataaac atagcgctca ggcttatcag gattggtaaa gcctgagatt
      361 ccctttaatt gcagatttaa ggcggttaag ccggtctcct cctttagctc acgcactgcc
      421 gcttcaaaaa aggattctga ggtgttaacc ttgccacccg gttggatcca gccaggaaaa
      481 tcgtcatgct ggcggttgag aagtaggatc ttgtcgccct ccttgacaca gatattaacc
      541 caatttttga tgacttcaag cattagttac ctcgttttta gttttatttt atcaaaaaaa
      601 gatcagtatg aatagctgag agatttattg atatggtcat aatggcttca gatagtttta
      661 ctgctgcttt agccatctgc ataaataata taaaaatacc atttcacatc attatttaat
      721 agatttatta tcatattaat ggtataatta tgtgaaatta gaactatgtg tagagagagt
      781 ataatgaata gtacagattt gatgagactg ggagagcttt ataaggagct tcgtattgct
      841 cgtggactta ggctaaagga cgttgctaga gacaatttat cagtttcaca gctatctaag
      901 tttgaaaatg gccagagcat gctggcagct gacaaactac tattagctat ttcaggaatc
      961 catatgacat tcgctgaatt tggtcatgct gtaaatgggt ataaagtcag cgattttttt
     1021 cagttaggca ccaaggttgc cgagctacaa acagcatcag atatagatgg attgaaggag
     1081 cttctgagcc aatataaggg tgatgacatt ttttctgttt ataatagatt aaatgaatta
     1141 atcattaaaa gtgctatcta ctcacttgat ccaaatgtta aaattgaaga atcagacaag
     1201 caattgttga cagaatacct ttatagtatt gaagagtgga cggagtatga gctatacatt
     1261 tttggcggtt gtttggctat tttatctgat gaggatatga tttttttggg aaaagcattt
     1321 atcgaacgag ataagatttt cctttctctt ccacaacata gaaaggcagc tcacatcact
     1381 ctcttaaata ttatcatgac aaggcagctt tttatgttga tttttttatt aaaaagctgg
     1441 aggagttgat tatctatcaa gatatgttca ctatagtgag cttaaatttt tttaagaaaa
     1501 tatataccta cttaaatgaa gaaagtaagc ataagagcga cattgaagat tatattaatc
     1561 ttgttaaaca gcttggcaac cctcagtttg cccaaattct acatcggacg ctatcagtga
     1621 ttctagatag ttaatactaa aaaagtagcc caatcgtttg gtggctacag tggccaaggc
     1681 caccaaatag acaaaagggc taataagaaa ataaaagctt ttcgcataat atctcacctc
     1741 cttgataagg atattataca aaggggaagc ttcaatctca aacattcgca aatatgaaaa
     1801 tattaacaaa agcatcatca tatttgcgaa tatcgagaat atgataattg tcgtgatata
     1861 attactgtgt taatgattta gctaggcatt aataaatcta aatatagact acaggcaggt
     1921 cgctcgttat actagtttga gggccaatgg tctgggtagg aggaagcgta tggcgacatt
     1981 agagcgacat cataaaatgt tattattgtc aatggcatta ggggcagcga gctggttagc
     2041 actcggattg attagcttgc caaatcttgc aggtgcttta ggaataagta ctgctaatgc
     2101 caatactaca gttaatttgt tgagtgctta tagtacagtt tctagcgttg ttgcaatcgt
     2161 tggtgctgtt acgggtgtag ggtctattgg agctggaatt gcagctaccg ttttatacct
     2221 tatcaaacaa aaaggaaagg ctgctgctgc tctctggtag ttaattgtct gatatgaagc
     2281 atgttttcaa atatcataaa ggcgacattt tagggtatct caatattgtt gggtttaccc
     2341 ttttgtttta tggctcagtg ataggtatga taatgttcag ggattatttg acctatgatg
     2401 gagctggttc tctaatatcg acctttattc tggtatcagg aacctatcat tctgtgaaat
     2461 caacatttcc atatgaaggg aagcgtcatc caacttttat attaacaccc tattatctat
     2521 ttaagcatct attgctttca gttacaaagg tttatgcttt ccagatccga gtggttacta
     2581 taggaatcat ctgtttagca atagcctttc cggagcagct tgtttggata gccttgtctg
     2641 tgctagcagt atttatatat tggctatcgc ttccgctagt agccattttt cgagtagctg
     2701 gacgactcct gaatcttctc atgatttatg gtatgtatct taatcaggag ctgctggtca
     2761 ttgcttgtct ttgtttaaat gtggttattc ttgtgcttag tgttacgatt aatgtacatt
     2821 atccctacca atggctggcg gtgagagcta ggaaggaaga aaaaacaatt accttgttaa
     2881 agcttgttat caatacgata acagatcatt tagctttaat ggttctgttt agtattttct
     2941 gtatagctgt gacctatttc acgcaaaggc tgctgctaag ttttgattat tctagcttta
     3001 gcataccagt ttttttctta tctgcttcta cctatatcgc gttactagag gttatggtcg
     3061 gtaaaaatat taaggagctt gagttagacc ggggcttggc tgttttacag tttctgaata
     3121 gggatatcag tgtttacaaa gcttatcgca acagccaatt cttgctttct gctcacatct
     3181 tagctgttat tcatacagga tgtgccatag gcttactacc atttttacta aatggtcaag
     3241 ctgctctttt tctgtctaac ctagtgatga tccccttcat ctactttata tcattttgct
     3301 atttcgtgaa atcactaaaa atagttgctg gtgatttgtc agtgtttagg tgggttattc
     3361 tggttttgta ttttatacta gtggtcattg caatggtagg tagtcgttta tgataatgag
     3421 gaaattttta agatattata tcagttttat tattttctca atagcaattg ggattttaat
     3481 cggtttgctg atcaccagtg atactgtcat attatctaag ccagagcggg gctgggattt
     3541 tactctggag gttttgaaga ataatagcaa taattttttg tcctatattt tcctcttctt
     3601 tttgtcccca gccttgcaat tgattgattt ggtatcagtt gttatacaaa ttactctagg
     3661 aatgaggaag tctggatttc taataactgc cttgggtttg tttccgcatg gtttgctgga
     3721 gatccctaat tttctctttt atcaaggctt gagtcaatat atgctatgga ctgttttgac
     3781 tgaaaaaagc atgacgtcct tcttagaaag agaaagaaga tatgtaaggt actatcttat
     3841 atcgtattat gttttgttaa ttgctggtat tatggaaggg ttactcggat gaaaatagta
     3901 aatgaaagca agtcattttc aaacagaaaa atcttaaatc acatatcctt tgactttagt
     3961 aaagggctgt ataaggttga agggaataat ggtagtggta aaaccacttt tttgcgcttg
     4021 ttagcaggct tagaacggtt tgatagcggc catcgcttac agcataaggg agatattcta
     4081 tatcttgata ctaatgctat cggtgtagtt cccttaacta ttgaagacaa tctgacatta
     4141 ttatggaaaa cctttaatgc ctctcctgat gaggagacct tgtctgtgat taatcagttc
     4201 tttggagaac ggttactaga tcattatctg acggcttctg taggaacaaa ggctaaggtg
     4261 ggcttatcct tgctttttgt aaaggattgg gattatattt tcatagacga agccctatca
     4321 acgcttgatg ggtttagtct tgatatggtt gcaggaagat tattagcatt aaaagaaaag
     4381 gctactgttt tttacgtttc tcataatcta tcacaccagc agctattgtc agaatcacag
     4441 gtgatttatc ttaatggaaa aggagaaatc tattgaaagg taatcctttt aatcgtaatc
     4501 tttcttggtt aatagcctat gtgctattac tttcttgtta tgtattcata ttagtagatg
     4561 gtggtttttt aaaaaacagc gttcaagaat tggaagtcct gctcggccaa acatcactag
     4621 ctataaagct gtttttgatg gtgatatcaa tagcttttag catcatatct ttactggttg
     4681 agtatttttt aagcaaattt ttagtgctgc tttttattga agctggcatc gtttctttaa
     4741 atgatgttct tactgctaaa tcagtgactt tagtgatcca tttatctgct ttgctattga
     4801 agctatctcc ctctccactt tttcagtttg tagtgaatgc tttagggatt gtgatcatgt
     4861 atggattgag tatcaagaga caaggaaata ggacaactgc tcttttgttt tgtttaccct
     4921 ttacactgga tattctagca acattgttgc tttagtgatt ttgagttgga ggaaaagtaa
     4981 tgaaaaaaat cttatattta tcagtacttt taggaacgtc aattctagca acattgatta
     5041 aaatttataa cacttttttt gcaaagctaa aggcttcatc aggtcattca actgggaata
     5101 tagagattga tgccctttta tctgagtcta gactagtgtt ggaaaggcag catgccttca
     5161 caacaaatgg aatcaacaag ctattcgtta tgatgatgag tctaatgctg ttattagcct
     5221 tatactatct gataaaaaag gatttgaagg ccgtctatag ttatttgctt tacctggtgt
     5281 taaccttggt tcatgcaatt tatagcttct tttcgttaag tcccttggca aagctttatt
     5341 ctgatgatat gctgggggct acaatccaga cgggagagaa agctaaattg attttttcag
     5401 tggttctttt tcttctttat ctgcttattg ttgtggccaa taatagagta aaatctagtg
     5461 tagaacccgc ttcatctatt gggatagatg tgtaatacct ttcatattat gacctttaaa
     5521 gccttttagc ttctctaatt ttcagagtaa ctaggaggct gtttgtgacg ctctgagcgt
     5581 tttttcgttt ctatcaaagt ttagctgcgt taatgctatc tatttccgta gctgagatac
     5641 aagatattat aatatgtgtt gtcataccat aaaaacacct tacaggatat tttatgatca
     5701 atcctccttg aattaagctt tctttaagca agggtgtgta tactagccgt aatcctaaat
     5761 aattggttac ctaatgataa ctaatttttt cataacctcc ttcctaaaaa cgatgtcagg
     5821 gcagtcagga ttgattgctg ttatggcatc gtttttgttg tactttgata ggggatctag
     5881 ctgtatgtta aatagcctat caggattgag tggcgaagat gatcaggagt ctcttggctc
     5941 taggttatgc tgctgtttca tgagaaacag ctcttgatga tcaatttagg tagtattagt
     6001 ggtggtcatc ttagcctttt aggctttgag ctgctttatg tttgctcatt tttaatatgt
     6061 tagtgtttac acaaataatt ctcatttttt gatataatag aaaaggtaag gaagggtagg
     6121 agataaggat gacaagattt tttcaaaaaa aacaggccaa aagcttagcc attggttttg
     6181 tgagcttgtt tgctgtgctc attgggtatg gagcttttca ctattctaag gccagtcgta
     6241 tcaatgccta tctacaagca aggtcatcag gctctgggca ggtgcttgaa aatatcaagg
     6301 aatacctcgt gtgggcagat accaatgagc agctgaccaa tgatcaagca agatacacca
     6361 gctttaagag atacagtaag gcagagctag taagcaagcg tcagcagctg caaacagcaa
     6421 ctgcagctga tgatatgtat gtcaaatcgg ttggtcgcaa atttttgatt ttccctgatt
     6481 atcgcatagc agtgaagcct gtagccttga caatcaagac caatgtgcca aatgttgata
     6541 tcttgttgaa ccataaaaag attgctgtat cacagtcaga ggattttagc acaactattg
     6601 aaagactgcc ggctgctgat tataaggcga gtattaatgg ctattataag gatcgtaaga
     6661 ttaaagtcag caaggcctat gatggcaaga accatacact agatttgagg gttaccttta
     6721 agacatttac ggtaaccagc aatgtcagag atggcgagct ttatattgat ggcgagcgcg
     6781 tggaaacttt gaaggctggg cagcttcagc tggaagaata ccctgtgaca gaaatcgcaa
     6841 aggcctatat taaaaagacc tttcctgatg gcgagctaac ctccagcaag cattcccttg
     6901 ctcctgttgc tgagggctcc cagctagaga ttaacattga tcacctcttg actgaggaac
     6961 aggcgggaca ggtgttggtg gcagcctttg atcaattgct cacctatctc aatcaagggc
     7021 aggatccagc aggtctttca actgtttttg agcaaggggc taataatgct ttttacaaag
     7081 gcttgaagga ttccatcaaa gcaaaatttc aaactgatac cagaaaggct tctcggttaa
     7141 gcattccgtc tattttgtta agtaagctaa ctcaaattgg taagcagtct tatctagtgg
     7201 actttacagc tgtttatgat tttgtttacg ataaggaaac tgatcctgaa aaaggcacct
     7261 cagggaatgt tcgtcaagac ttgactggta agctgaccct gaaaaaatct ggggatagct
     7321 accttgttag tcagtctggt cctaaaaata ttacagttgc cagcgaaaaa aatcaggtca
     7381 agccgtctat tttcccagag gggctagtgg gaacctggat aggacatcgt tcggacatga
     7441 cctttacgat gatattggct aaggacggca gcatcacaac aaccattgga aacaaaaatg
     7501 ggaatggctc acagaccact aagtctgcta aaattaccaa ggtagaggaa aaaggagatg
     7561 gcttgttcct ctacactgta gctccagatg ctgatatagc agctcttgtt ccaggaggtg
     7621 gattgggtgg tgtcaatgtc aaatacgctt ttggtgtcaa atggagtgga gatgtcgcta
     7681 cgatagtggt ttggcagaca gcaaataatg cggcatttga ttacagtaag ccaatgcttg
     7741 gccctgacat gaaaaagcaa taagtacttt accctacaag ttggtctagc atttattgct
     7801 aggaggaatc agcataaaga aaaagcctct cttttaatct tttgtggtta agaagagagg
     7861 ctttttagta tagggctgac tgtatgagga gcaaccgatg taatcaattt agctgctgta
     7921 gtccttcttt aaagctttta gacggggcag tgaccctaat catctcttga gccaaggggt
     7981 gtctaagggt tagctgatga gcgtgcagca tgagacgctc cgctttttgc ctgctataga
     8041 ggggatcacc aattagaggg tgtttatgat gagcgagatg tactctgatt tgatgtgttc
     8101 gtcctgtctc taggcgacag ttgactaggc aggtctgatc aaaggcttgt aataaggcta
     8161 gatgggtgat tgcctcttgc ccatgcttac tatcaaccac acgcttgcgc ctatcgtggc
     8221 ggtgacgtcc gattggatcg cgataggtta ctgtttgctg ctctagctga ccttcgatta
     8281 gggcccaata atctcgctta atgtctcgat gctccaatag gcgatttaag atcggaagga
     8341 taaagggatt tttagcaaag agaatcgctc cactagtctc catgtctaag cgatgaacca
     8401 catagcaggt cttgccagta taggcagaga catggttgag caaggcgagc tcagtgggct
     8461 cattgccatg tgttttcatg ccctcgggct tgttgacaat gatgaggtgt tcgtcctgat
     8521 acaggcaatc cactaggcca ggcttaccca ttaagatgcc tttatcaggg tagtcttctt
     8581 ggtcaaattg tagcttgatg tgatcaccct gcttgacagg gctctgccag ttaatcagct
     8641 catcattgac ccaaacatgc tttttgatgc gcaagaaatg tctgatttta cggggaatca
     8701 atagcctatc ttctaataac tccttgacag ttgtcgcttg ataggggtta atgaaggaga
     8761 tctgaaagcc catctcaggc ttatttgctg ttgtcattga gccagtcatg gtatttttca
     8821 atcaaattga tggccatttg ggttgcaaga gttacagaga aagcctcggt tccctcgcgc
     8881 tcgtcactgg caacctctaa gcgtgtctca tcatagacag ccttgaggct ctctgctgac
     8941 agggtttctt taaaagcttg aaatttgttc atgatcatgt cctacctttc taaatgtttg
     9001 tgacaatgct attatagcat atttttcatc aaagctaatc atttgctcga tgatttgtgc
     9061 tgcgctaaca gcgtgattct tttgagaaaa aataagatta gctattgtga aattgtctgt
     9121 cttttattat actaagaata gtctgataaa tatattattt aaggacacga taacattggg
     9181 attatgaatc atttaggaga atactattga acaagccatt gataaaatcc tgtttgcttg
     9241 ctctattgac cttggccggc ttgaccagta tggcagcaca ggctgatgtc aacacttaca
     9301 accaaggtag gacatataac gatacaccct attattctgc ttatcatcac tactatgacc
     9361 acacgaggga tactgctgac aatggtattg ataattgggg tcgtctgaca cgctatcact
     9421 attacagaga gacctattat cagcttgagg ccgagcgtca gcagcttgtt aggacttact
     9481 tggagttgaa ggcttcatat gatgatcagg tggctcttag cagtcaacga ctacagcagt
     9541 accagtctgg ctggtctgat ctccaatcac gctttgagca gctcaggaaa accaatcctg
     9601 ttgtaggcgg tgattatcgg attgttgagc tagagggcaa ttttcaaagc tatcagacct
     9661 tgctgcagca gctttctatg gctgattttg tcagccagta caaagatagg ctggatacct
     9721 tgactagact tgatacagag cgagctaggc tcattgacac ctggtgggaa agtgatagca
     9781 attactcaga tctcaatacc aatctaacac tagtcaatgg ctatatcaag gagctgaatc
     9841 aggctttaca ggagcttctt aaggaccatc aaggtaaaat gacatcagat ctgcagacct
     9901 tgggtgaccg acaggccgag cttgctagac ggctgacaga tatagaaagc aggcctaaga
     9961 gacaggctac cagtcaacct cgtggttcac agacacattg gcgatcagcc cctagagctg
    10021 atgttgcctt gtggaatgaa ttgcgaaacg aaggagatta tgcttctgct acgacagaca
    10081 atgctttgcc attgcagcct tatcgagcgg acttaacagc tgttcatgat ctagaagcct
    10141 tgcaagcaca atctgataga gcacaccgct tgcgggcaaa ggaaattgtc tttacactgc
    10201 agcgttctaa cattagtcgt cagggcgata tagatttgtc aggagccatt acagcattta
    10261 tcaaagaaaa gcttctcgtc actccaaatg cgcgtggggt atcatctggc tttaggtggc
    10321 aaatgcaaac ctatgacaat gagcgcttaa ccatcactct aatgcctcaa tattatatga
    10381 ctgatgatca gtacaaggag tattacgacc atctcaaggc ttggacagct cagcatatcc
    10441 agtctaccga tacagaggtt gagaaaattg ataagattca agactatatc atgacaaact
    10501 accactatgc gaccggcaag gttggaggag tgacccgtac tggcatttct gtgcagacgc
    10561 catatgcctt tatcaaggac aaggaggctg tttgtcaggc ctatgcacag atgtttaagg
    10621 acatgggacg actagctgga cttgatgttc attatattca aggctatgga gacccagttg
    10681 gcggcttatc aagtctacat gcttggaata tcgtcaaggt tgatggtcaa tattatcata
    10741 ttgacctgac ttggaatgat actattgaca gcaccaatca caatcatacc tacaccctgc
    10801 gaggcaatga ttttatgagc aaaacacatt tgtggaatgc tgcctatgcg atctcagata
    10861 gtgactatgc tgcttatcct aggaggagct tcctgagata tgggacctat gcgactaact
    10921 attcaagaaa tacattttat ccaggataca gttatgctta ataatagcta ataccatcaa
    10981 aagccctaga aagcttgctt gattctttca gggctttttg atatgtcatg gtttttggta
    11041 taggattttg aaagaaattg ttataatagg ataaaatgct tatgtaacag gagaaaataa
    11101 aatgaagagt attagacgct atgatgtcaa tgaagagtgg gcacatactg gcttagtaga
    11161 ggcaggcgat ttttattttt taaattattg tgtaggaaat gtcggtcaag atattgaggc
    11221 tcaaattaac ggtgcctttg atgaaatgga gcgtcgtttg gggctggtag ggctgacgct
    11281 agaggtcgtt gttcaaatgg attgcttgtt tagagacatt tggaatgtgc cagttatgga
    11341 aaaaatcatc aaggagcgat ttaatggcaa atacccggct cgtaaatttc ttcaaacagc
    11401 ctttgctcat cagggtggtc cggacggctt gctatttcag gtagatgggg ttgcttattc
    11461 aaagcatatc tccgtatcct aaacaatatg acttggaggc ttagtagtat cataaggcta
    11521 tgacattttt agaattatta caaaagaaat tttttccaaa aaaataccaa gaaaaacagg
    11581 ccttaaagga aagggcagcc cagcatatgg ctgacaaaga ggctactact caggctactg
    11641 ccactgcttt ggccgatcag gaggcacagg cagggcagac tgagaggcaa tcagtccttc
    11701 aacgcagcaa gtcctatggg gtcaaaagga aaaatcggcc gatctggctt caaaggctgg
    11761 aggcgatttt gccatcgcag caaggtccta ttcgccgctt tcttcgtcgt taccatgttg
    11821 gtaaaatcct gctgattttg atgggtacct ttgtcttgct gctggggtct tacctttttt
    11881 acctttcaaa gacagctaag gtttctgact tgcaggacgc tcttaaggcg acgacagtca
    11941 tctatgaccg caagggagaa tatgcaggca gtctttctgg tcaaaagggg acctatgtgg
    12001 agcttgacgc tatttcagat gatttggaaa aggcggttat tgccacagag gaccgtacct
    12061 tttataccaa caatggtatt aatttcaagc gctttttatt ggctattgtg accgcaggac
    12121 gctttggtgg aggctcgacc attactcagc agttggctaa aaatgcttat ttgtcccagg
    12181 agcagagcat taaaagaaag gcgcgtgagt ttttcttagc acttgaattg accaagaaat
    12241 acagtaaaaa tgacattttg accatgtatc tcaataattc ctattttgga aatggtattt
    12301 ggggtgttga ggacgccagt caaaaatatt ttggtacctc agcagctaat ctaaccttgg
    12361 acgaggcagc aacccttgcc ggtatgctca agggacctga aatttacaat ccctattact
    12421 caatcgaaaa ggcaaccaac cgtagagata ctgttttgtc agccatggtt gacgctggaa
    12481 aaatcagcaa gcagcaggca caagaggccc aagctattgg tatggggaac cgtttagcag
    12541 acacctatgt cggcaagaca gatgattatc agtacccatc ttattttgat gctgttatca
    12601 atgaggctat ctcgcgctat ggcatctcag aaaaggatat tgtcaatgat ggctacaaga
    12661 tttacacaga gttggaccaa aattaccaag caggcatgca gaccaccttt aatgaggata
    12721 gcctatttcc tgtgtctgag tttgacggca gctcagctga ggcggctagt gtggctctag
    12781 atcctaaaac cggagctgtc agggggcttg ttggtcgtgt caatagcaca gaaaaccagc
    12841 cctttagaag ctttaactat gctactcaag ccaagcgtag ccctgcttca acgatcaagc
    12901 ccctagttgt ttatactcct gctgttgcag caggctggtc actggagcac gaactgccaa
    12961 acagcgttca ggattttggc ggttatcagc cgcataatta tggcaattac gaatcagaaa
    13021 caattcctat gtatcaggct ttggctaatt cctacaatat tcctgctgtt tcaattctgg
    13081 atcagttggg ggtggataag gcctttagct atggtgaaaa atttggtttg aagatgagtg
    13141 aaaccaaaaa ggagcttgga gtggcgcttg gtagtggtgt caccaccaat ccgcttgaga
    13201 tggcacaggc ctatgcagtc tttgccaatg gtggtgtcaa gcatattgcc cacctgatta
    13261 ccagaattga aaatgctaag ggcaaggtta tcaagacctt tacagacaaa accaagcggg
    13321 ttatcagtca atcagtggct gataagatga ctagcatgat gcttggaacc ttttctaatg
    13381 gtacagctgt taatgccaat gtctatggct atactctggc tggtaaaaca gggaccacag
    13441 aaactgactt taacccggac ctttccggtg atcagtgggt cattggctac acgccagacg
    13501 ttgttatcag tcaatgggtt ggcttcaatc aaaccgatga gcatcattat ttatcagatt
    13561 caagtgcggg cactgcctca gcaattttta gcacccaagc ctcttatata ttgccatata
    13621 ccaaaggaag ccaattcaag gtcgataacg cttacgctca aaacggtatt tcagcggttt
    13681 atgggattaa tgagaccaat acgcaagcag gtattgattc tcaatccatc attgatagtc
    13741 ttagaaagtc agccgaggaa gcttcaaagt ctatttcaga ggcagttgat caatctggtc
    13801 tcagagaaaa ggcgcaaagt atctggaaga gtattgttga ctactttaga tagcttgcga
    13861 aaatatctaa atcgtgttag aataatcact acggaggcgt tatggcacag aaaaaagcaa
    13921 gcctagcgtg tgtagaatgt ggcagccgca attattctat cgggattagt agcacgccta
    13981 gaccaacacg actagaagtc aataagtttt gcaaatattg taaagcatac accttacaca
    14041 aagaaacacg ttagaggaga gcctgatggg attcattagt gggattttta agcttttaag
    14101 ggatacaact tggccggatc gtaagcagcg ctggaaggac tttatttctg tccttgagta
    14161 tacagcattc tttacggtaa tcatctttat ctttgaccag ttgctatcaa aaggcatttt
    14221 atcattgatt aatttattct aagtcattgc aatgatgaga cctgttatga ttaaaattgc
    14281 ttggaaaagc ctaggctgaa acaatcgttt cggccttttt gagtgcgatg ggcaggttgt
    14341 actctgatag atgcaagacc aatagaccac ctactatgcg ggtgcgtaaa ggggttgata
    14401 gctaccgata gttaagggct atagcaagta gaaaggcttg cagctcagct gatccgctgt
    14461 tatgactaaa ggcattgacc agaaaggttc gttggcagcc aacaaagtgc tcttaccctg
    14521 ctatgagggg ctattaatgc gttgacagcc aatccttctt ctattataat gaaagtgtga
    14581 taacagcaat gcaaaggcca gcagaggctt ttttataatg aaaggaagta acatgttaga
    14641 ttcttttgat aagggctggt ttgtccttca aacttactca ggctatgaaa ataaagtaaa
    14701 agaaaacctt ttgcagcgtg ctcaaaccta taacatgcta gacaatattc tccgcgttga
    14761 gattcctacc caaacggtaa atgttgaaaa aaatggtcag gtcaaagagg ttgaggaaaa
    14821 ccgcttccca ggatatgttt tggttgagat ggttatgact gatgacgctt ggtttgttgt
    14881 tcgtaacaca ccaaatgtga caggctttgt cggatcgcat gggaaccgct caaaaccaac
    14941 ccctctactt gaagaggaga ttcgtgctat cctgttgtca atgggacaaa ctgttgatgt
    15001 ctttgatacc aacattaaag agggcgatat ggttcaaatc attgatggcg cctttatcgg
    15061 gcaagagggt cgtgtcgtag aaattgaaaa caacaaggtc aagctcatgc ttaatatgtt
    15121 tggctcagaa accttagcag aggtcgagct ttaccaaatc gcagagctat cgtcctgata
    15181 ggctcctaaa gctattattc ataccataaa aaataaaagg ctggcatcgg ctctctaaaa
    15241 taccgatgtt aggccttttt tgttggtctt ctacaaccaa gactcaaatt aaccaaaccc
    15301 taaaaagagt catttttcct tcgcttttta agtctctaac tgatcgccct agcttatttt
    15361 taatctagta atcgcaacag gtcaagagtt aaatgatatc gcgccgttat tgattggtat
    15421 agacaaaaat acgctcaaaa aaagaaaaaa ggataggtaa tatagtcctg gtttgcttga
    15481 tagatggtgg ttggcaacca accattcgag tactttcctt aactataaac tcctaatcaa
    15541 ttctagcgtt taaaaaataa gattattctt ggagggaagc aaagagcttc tctccttttt
    15601 gagttgtagc attcttgatc ctgatcttat aagcagagtc ctgtttgccg ggctgttgag
    15661 atgaataagg gcatttctat agtgattata tagtgttgca gatgtgtgta tggtttaagg
    15721 tctaaatacc cttcaagctt agttcttggg tagtcagttc ggattggctg gctgattttt
    15781 aagcctttaa tggcttagtg gtaagacaaa ccagattaca tttgctaaaa agtccctaag
    15841 gctacaatca ttttttgtga ctaatataaa aactagacct tttgggattt gtaataattt
    15901 agatt
//
LOCUS       DARYLJ010000045        15640 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYLJ010000045 DARYLJ010000000
VERSION     DARYLJ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15640
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..1034)
                     /locus_tag="TU746_001541"
     CDS             complement(<1..1034)
                     /locus_tag="TU746_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891861.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
     gene            complement(1040..1894)
                     /locus_tag="TU746_001542"
     CDS             complement(1040..1894)
                     /locus_tag="TU746_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891862.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            complement(1961..2161)
                     /locus_tag="TU746_001543"
     CDS             complement(1961..2161)
                     /locus_tag="TU746_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0891863.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            complement(2534..3271)
                     /locus_tag="TU746_001544"
     CDS             complement(2534..3271)
                     /locus_tag="TU746_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0891864.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            complement(4022..4327)
                     /locus_tag="TU746_001545"
     CDS             complement(4022..4327)
                     /locus_tag="TU746_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL0891865.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            complement(4329..4667)
                     /locus_tag="TU746_001546"
     CDS             complement(4329..4667)
                     /locus_tag="TU746_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL0891866.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSLGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            complement(4695..5450)
                     /locus_tag="TU746_001547"
     CDS             complement(4695..5450)
                     /locus_tag="TU746_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL0891867.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            5711..6166
                     /locus_tag="TU746_001548"
     CDS             5711..6166
                     /locus_tag="TU746_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL0891868.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            6150..6800
                     /locus_tag="TU746_001549"
     CDS             6150..6800
                     /locus_tag="TU746_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL0891869.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            6910..7814
                     /locus_tag="TU746_001550"
                     /pseudo
     CDS             6910..7814
                     /locus_tag="TU746_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(8167..8442)
                     /locus_tag="TU746_001551"
     CDS             complement(8167..8442)
                     /locus_tag="TU746_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891870.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(8865..10415)
                     /locus_tag="TU746_001552"
     CDS             complement(8865..10415)
                     /locus_tag="TU746_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0891871.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(11086..11646)
                     /locus_tag="TU746_001553"
     CDS             complement(11086..11646)
                     /locus_tag="TU746_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0891872.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(11624..12493)
                     /locus_tag="TU746_001554"
     CDS             complement(11624..12493)
                     /locus_tag="TU746_001554"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL0891873.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            12585..13856
                     /locus_tag="TU746_001555"
     CDS             12585..13856
                     /locus_tag="TU746_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL0891874.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(13892..14230)
                     /locus_tag="TU746_001556"
     CDS             complement(13892..14230)
                     /locus_tag="TU746_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891875.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(14330..15418)
                     /locus_tag="TU746_001557"
     CDS             complement(14330..15418)
                     /locus_tag="TU746_001557"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL0891876.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         4832 a         3442 c         2720 g         4646 t
ORIGIN      
        1 taggccaatt ttaataataa ttcttgtgta ccaaaggttt gtacggatac aaatgttaac
       61 agtttgttca tcaaaccttc tggaaaaatt cccattagaa agaccggtgc atatacaata
      121 agagcagata taccaaaagt ggttagagga gacttagtta gagatgaaac tagtgcatga
      181 atgcctgtca taaatatcag gccaatatac tgaaacacca ataaatagac aaacgcaatg
      241 cctaaggtca tcttttccgg gaaagccata atgtttatca ctggatcaat ccaatacaaa
      301 ttgagttgta agctagtgtc ccagccgcta aaaccaaaat aggtcgcaaa gacagcaaag
      361 accagaccac tagcaattgc aaataccaaa gtactgacag ctatgctaac tgctaattta
      421 gcaagagtca atttaccacg tccaaaaaca gtcgtcaata agatagagtt catcttttta
      481 gatgattccc ctgaaaataa aggagccgtt atataaagac aaagcataac aacaagaaga
      541 taagtactat tggttacatc aaacaactga ttccaaggag caaaattacc taacttcaac
      601 tctttcaaag gcagagcgga ccccaactct tcacgtgatt tgagatgaac attgtcaaat
      661 gtcagagact tatcagtgct attaatagcg ataagcttat cagtagactt aggcactaaa
      721 tgagagatag cataatgtga taccacacta tatacaccct tcttttttag gtctgattga
      781 tttttagcat aatcattgag gatacgacta atcagatcgt cagataaata acctgtatgc
      841 ttctcagcaa tttgttggtt aattgctaca gctgcacgtc catgaacctg atctgcagaa
      901 gagccactga tctgaccgtt aaaaaaatgc tggtaaaaaa gaccacctac agccaataag
      961 accactacaa tcgcaccaaa taccgactgt cgtcttaata attttttaaa ctcaaagggt
     1021 atgagagatg ccatagaatt cactcctttc taaaatgata aatgtagaga tcctctaatg
     1081 ttggtgacac aggatttgcc tgataacaag gactctcatc gctcacaaca cgtaagatac
     1141 gattattttt tacaattttt tcattgacaa cggcatagtc agtcaaaaat gctggtgcac
     1201 tctctgtagc aacaggaatc tcccatacct tgccgatcat tgtttgaact aactgatcaa
     1261 cacttccttt ttctataaac tgaccatgct ttagaaggat tacctccttt gcaaccgctt
     1321 ctacatcaga tacaatatgt gttgatagga taataatttt ttgctctgat aaatcactga
     1381 taatatttct aaattttaca cgttcctttg gatcaagtcc gactgttggt tcatctaaaa
     1441 ttaacagtaa aggatcgttg ataagtgcct gagcaatacc caatcgctgc ttcataccgc
     1501 cagaataaga agcaattttc ttttttctaa catcataaag acctaccagc tttaataacc
     1561 gatcagcttc tactaaagcc tttttacgtt taacattctt caaagcagcc atataaagaa
     1621 ggaattctaa accggaaaac tgctgataat aattaaactg ttgaggtaaa aagccaatat
     1681 tctggtaaaa gttttttggt tgttgttgat gatttaaact aatttctcca ctatcaggaa
     1741 ctgtaaactg actaatgatg tttaataaag tcgttttacc ggtcccattt gctcccaata
     1801 acccatacaa gcctggtgta aattgtgcag aaatacgact caacaccttt ttacttccat
     1861 aagatttaga aatattatct agtattaaca acattgtcat tcctcctaag taaaaaccca
     1921 gggaacagca ccacttcgct gctccccaga tgattaacca ttaagcatta tatactcgac
     1981 aaacggtacc aggataaaga atcatgtggt tatcagcatt ttcttgtgct gtatctctta
     2041 atagatgcca tgcacttgta taaccatcag tgcatctcca cctataaccc caaccacctt
     2101 caacgcctgc aagcatatca gcagtcattg tactaaattg ttcaattgtt tttgtattca
     2161 tatcgaatac ctccttataa tgattttatc tagctacagt ctcgacaaac ttagtgtagc
     2221 gctttttaaa gcaacgacac tcaaaaatct tgaatggttc ttattttgtc gtgaatggtc
     2281 aatttttctt ctgaaattac cagttaagat catatggata cctttcacga gctatatctt
     2341 tttctctctt ttcttatgat ataattgatt tttgcatgta catcatatct ctgagcatca
     2401 ttagaaacca actgttaccc ctttttctta gttttgacta aatatattta taataaatat
     2461 cccttaaggt aaatggtatc aacgaggttg attaaaaaac aaatgatggc ttccacatgg
     2521 cattctttta ctgtcaatgc aaagccttaa tagacgcctc aagtgctttc atttttagtc
     2581 ttgaaaccat gcaagactgc ccattcttga aatagagtaa acgcttatca cgatcaagaa
     2641 acgaaacatt gtaaggattg ataacataag aacgatgaca ttggactagt ctggaatctt
     2701 gcttaagaac ctctgaaaga aagccataaa attctattcg ctcgttttga gaatgcaaaa
     2761 tcaacttgtg aggagtacta gaggtctcaa tgaacaatag gcttgaaaaa ggaacctgca
     2821 cctgagcctt agccgttgca aaaataaata agccctctga ggttacattt tcttgctctt
     2881 cataagcata tataatggct ctttcaatcc tatctgagaa atgtttcatt gacaattcct
     2941 tatcgataaa atctagagca gacacctgat aacgaaaaga aactggcata agctcagaat
     3001 gtgtggtgac aaaaacaatg agggcataag ggtcacgctt tctgatctca cgagcaacag
     3061 ctaagccctt tttctcatca tttcgaattt gaatatcgag aaagaaaagc tgatgcctgc
     3121 ctctctctgt aacatttgcc agaagctggt agggctttcc ataaacttca aaacgatcac
     3181 aagtccagtg atgcttatcc aatatctctt gaatcttcat ctcaagccta aactgttggc
     3241 ctagatcatc ttcgagaata aaaatattca tttagaacct ccttattgct ttagcttatc
     3301 gtttttttag gagactaaag cagctttttg aacaagtgat agctagaacg ctctccttca
     3361 tgaacagtat ctttttagca tcaccattaa aaccatgacc gttaagctta ttaactaaag
     3421 gttgtcaatg acttctaacc aacttgtcat tgcagcgttt tcaataggcc ttagcgaatc
     3481 acgcgcctca aacaattttt ttaccacaga taatatacta gcacgagccg caagtcatac
     3541 ctctttgaga gagagctctt aacgactatc acttttgttt gacaagtcat cagctatcaa
     3601 tccacacact gatctccttg cacagacatt ctaacacaaa gctagggagc agggagttaa
     3661 aatcttaaat ggtactgatt atgtcttaaa tggtaaataa ggaaaactaa caatggctag
     3721 tcaggttact gaggctatct gatgattagc tgcttgtagc tataccttct ccaagcaata
     3781 agtttctaga attattggta acaaatacat taggtatccg ggatattctg tcatttattt
     3841 tatcataaaa acaatctttt tatcatcaaa acaggtaatt gttattatta ttaatcactt
     3901 tgagtgattt gaagtaagct agatcttcag ctaaacctta tgacactaaa cacaaaaagc
     3961 cccctaaggc agctaaaaca ccagcctagg gggcaagatt caagagagtc actctatact
     4021 tttagaccat ttcaatttgc aggtatttac aatttgttgc agcctctaaa tgataaaact
     4081 gatgagcaga gatactgatc aatccgcctg ctttcatgtc atgagcctga tccgtaagac
     4141 taaccagcaa ccttccttct aagacaagca ggagcttacc ttcagggctt gattcgttac
     4201 taatcgtctc tccctgatac atggcatata aaacaacaga ttgcttaaag cctaggcttt
     4261 gatgaagcga acgactagct atttggtcat catgatacct tactaattct aataaatcag
     4321 ccaacatgct aagcctccgg ctttacaaca actaaaagca tctggaaggc ttccttagca
     4381 aataagctat gaggaatatt agcaggcatg atgatcgtct cgccagcagc tacctcataa
     4441 caggcttctc caatagtaat gtcaactact ccacttaaca cgttaaccat tgcatctccc
     4501 agtgatgaat gacgaccgat ttcttgtcct ttatctaatg aaaacagggt tatgcccaaa
     4561 tcttttcttt gaactagtgt tcgacttaat atttgatcct cttcaattgg cacttctgcc
     4621 tttaaatcaa tgactgtgct tgttggaatt ttacgaatca atgacatgtc acttctcctt
     4681 taccattatt ctagttattt ttgacttaca gcggcaatat aacacagctt tcttccagtt
     4741 ttgttgaaga aatgacgcat ctttaaaaac tgctttcgat tttctttttt catgccgcgc
     4801 agcataatac gaatcgcagc gacaacccct tcatctttaa tcatgccaag cggggacatg
     4861 agcgtcatat taccatagga gtaattgact gctgtgaagc cactctttac cagcaattgt
     4921 ctccaggcat ctaactgcaa tggcgatacg ttcacattaa tcgtatctct tagttgctct
     4981 ataatagcct ttgtttcatc agcttcatag gaaacatcat gcgttagtag gcgaccaccc
     5041 ggctttaaaa cacgccaata ttccttaagt gctttttcct ttgcagcatc attcaacatg
     5101 gttagcatag cttcgttaat aacgatatca aagctattat ctgcaaaagg cagcttcaag
     5161 gcattagctt gggtaaggtg aatatagtct tgcatttgtg ctgcctcaat agcctttctt
     5221 gcctccgcca gtaccttggt atccaaatct actgctgtaa tatgacactg ataagtctgc
     5281 gccagctcaa tggaggtcgt gcaacggttg caggccactt ccaagacctt gcaatcactc
     5341 gaaaactctc cttgctgaac cagccaattc gtcgcctcaa caccgccagg ccgtagtcgt
     5401 ttctttccca gtcgagctaa aaactggtga ccaacttctt tttgagacat cacatgccct
     5461 cctatttgct ctgctatata tcatcactta gaataaacta actgttaaca aattgatcaa
     5521 taaatgatta ctacaactat atcacactta aagcatatcc tcaatgaagc ttaagcattt
     5581 ctgatgattg tttttatgat aaatcataga attggctcat atttcttgtg ctatacgacc
     5641 ttttgacttg ctattatttt ttaaataata tataatctag ttatcaaaac tagataaaga
     5701 ggttttagta atggaatatg ataagctgcc cagctggaag gatttacctg atttggagtt
     5761 atacttagat caagtgttac tctatgtcaa tcaggtcaca caattgagtc aagccacaga
     5821 ccataagcta ctgactgctt caatgatcaa taactatgtc aaacatggct atattgataa
     5881 acctattaag aaaaaatatc aaaaaaagca ggttgcccgc ttaattgcta ttagcatttt
     5941 gaaaaatgta tttcctattc aagatattag tcaggtcttg acgagcctac aagcagcctc
     6001 cagctcagag gtcttgtacg atacctttgt caactattgg aataatggcc ttacccaatc
     6061 aacgcctgaa attattagct atgcttgtca aaccgtcaag gactatcagc acacaatgaa
     6121 gctttcaaga gaaatggagg ataccaagca tgaaccaaac ctttaaacaa agtctcccac
     6181 tatcagttaa tgaagaggtc gcaaatagtg tgacacacgc tattggagca gctgctatgc
     6241 tgatactgct acccatcact gctatttact cttaccagac ttatgatctc aaggctgccg
     6301 ttggagcatc tatttttatc atcagcttat ttctcatgtt tttatcatca acgatttacc
     6361 attccatgtc ctatggaaca actcacaaat acattttacg tatcattgat catagcatga
     6421 tttatattgc tattgctggt agctatacac ctgttgcctt atccttggtt gagggcttgt
     6481 tgggctatgt gattatcata ctccagtggg gaatcacact ttttgggatt ttgtataaaa
     6541 tttttgctaa aacgattaat gaaaagttca gtcttgcgct ttacattatt atgggctggt
     6601 tggtcgtttt tatcctgccg gtgattatcc aaaaggccag tctgccattt ggaatcttga
     6661 tgctactagg tggcttatcc tatactgtcg gcgcaggctt ttatgctaaa aagaagccct
     6721 attatcacat gatctggcac ctttttatcc ttttagcctc tgctttacag gttattgcca
     6781 ttattttcta tatgctgtaa aaagtagctg ttgctacttt ttaaacgcga gcgcttgctt
     6841 acccccagac acctggcttg attcatgcta taataaaggg cagtaaatag ttgaagggat
     6901 caaagcaata tgaaaacggt acatattttt tacaatccta attcaggaaa accagaaaat
     6961 gacctggctg aaaaggtcaa gcattatctg attcaaaatg gtttttctga agacaaggtt
     7021 cagattatta cccccaaaaa tgctgatcaa gcctttcaat tagccaaaaa atcctcacag
     7081 gatcatattg atctagtcat tcctctaggc ggagatggga cacttaataa aattattgga
     7141 ggtgtttatg aaggtggtgc tcattctgtt attggactcg taccgtcggg cactgtcaat
     7201 aactttgcaa aggccttaaa cattccactc cagctaactg aggcacttga gacgatttta
     7261 tctggcacga ttaaaaaagt agatatttgc aaggtaaaca agggctatat gatttctagc
     7321 ctaaccttgg gtctgcttgc tgatattgcg gctaatgtga ctacagaaga aaaacgaaaa
     7381 tttggccctt ggccttttta aaggatagta ttaagatact aaaacgaaac cgcacatatg
     7441 caattagctt aattagccat catcatgttc ttcacttgaa aaccaaattc ttattgatta
     7501 ccacaaccaa tactatagca ggtcttccat cgttttcacc aggtgcacaa gctgacgatg
     7561 gcttgtgtca agtttacacg atgagccagc tatcatttct gaaatgcttg cgccatatta
     7621 gagactttag acggggggat ttttccaagg taaaggagat tagccatttt caagctgatt
     7681 ctctaaagct attgccacaa tatcagcgtc aatcagccat tcctagaact cgcattgatg
     7741 gcgataaggc tgatgatctc cctgttgaat tgaaggttat tccaaaagcg atttccatta
     7801 ttgttagcca gtaaaaaagt gccctagggc actttttgat atagattcat ctccaagctg
     7861 agttttagaa aactaagcta tagctataac gttagctgtg gcttcttctt gctggcttgc
     7921 agtactcttt tcttgtctta acagctagct ctttcataat atcggcttta acaaagaagc
     7981 tatctgacta gtccgatctt ctattctcag gacaaacagc gagaaagggg attttctttg
     8041 aatcctagag aaccttagct atctctgtgt ctcattgtaa gtgcagctct attgactgat
     8101 gccagctata gcaataagcc cagtcgcata ttataaagga ttatcaggcg atttagcttg
     8161 acactcttat atctttattg cttcttctaa ggttccttta atagctttag ctgctgaatg
     8221 accacaggca ttagcagcaa ccttagaggc ttctacctta tcagaggctg tctcaataag
     8281 ttgtccaccc ttttcttgga tataatggtt caactcctca atagtttcag agccttcctt
     8341 taagagctct ttctttttgg ctgaggataa gcttaaatat gtcacagcaa ttgctgctga
     8401 accaagaagt aatcctaagc cgattccata gctttttttc atcatcaacc ctactttcta
     8461 tgaccttcct taatcatctt tttagctaat tttacagctg gtactactaa aagcaccaat
     8521 tgtaaaagat ccatatactt gatttttcgt cgttttttca ccatgtgcta tttccttttt
     8581 cttgtttgca ccatacaatc gtcttttatt gcgcagtgcc agagactgcc tgattaggca
     8641 gcgtaagcta agaactatca gcgtgtcaga ctagtctaga tacagctaag cactagcttg
     8701 attacgataa tacttaccgc taggccataa gctcagctat catcaaatct aaagtgacaa
     8761 cgctttttat ttattatatt gtcattttac taaaatacac aattatcgtc aatgcttttg
     8821 ctttaggcag caaaaatgcc caagataaag accttggaca tctgctacaa tgacgttaat
     8881 tgattgaaat cccaaatatc agttacccag ccctcataaa actccggctc atggcaaacc
     8941 atcaaaatag agcctttata gacttgcaag gcgcgtttta actcctcctt agcatctaca
     9001 tctaaatgat tggttggctc atctaggatt aaaacattgt gctcacgatt cattaagaga
     9061 caaaaacgaa ccttggcttg ctcaccaccc gagagcccct gaatctggct ttcaatatgc
     9121 ttagaggtta gaccgcaacg agctaaggct gcccgaacct ctgcttgatt taaagcagga
     9181 aaagcgtccc atactgcttc tagtggcgtt tgacgcttaa cacctgcagt ttcttgctca
     9241 aaataaccaa gctccacgaa atctcctgtt tccacctctc ctgacagtgg ctgaataatg
     9301 ccaagcaggc tctttaggag ggttgactta ccaataccat tagcaccgat aattgcaact
     9361 ttttgatgac gctcaaatgt taagttcaag ggatcttttg ttaggggtct gtcatagccg
     9421 atgacaagct cccttgtttg gaaaataaag cggcttggtg ttcttgcttc cttaaactca
     9481 aagcttggct ttggtttttc tgcctgaagc tcaatgattt ccattttatc aagcttcttt
     9541 tgacgggaca tagccatatt gcgagtagct actctggcct tattacgatt gacaaaatcc
     9601 tgtagctctg caatctcttt ttgctgacgc tcataggctg cctctagctg agcttttttc
     9661 atctcataga cttccttaaa ctgatcgtaa tttccagaat acctaaccaa attccgatta
     9721 tcaacatgat aaacaatatt aatgacatca tttaaaaaag gaatatcatg tgaaatgagc
     9781 acaaaggcat tgtcataatg ctgtaaatag cgctttaacc actcaatatg ctcagcatca
     9841 agataattgg tcggctcgtc cagcagcaaa atatctggct tctccagtaa cagcttggcc
     9901 agcagaatct tggttctttg ccctccagat aaggaggtca cttctgtttc catcccaaaa
     9961 tccataactc ctaaggcacg cgcaacctca tcaatcttag catctagggt ataaaagtcc
    10021 ctgctttcaa gacggtcctg tagctctccg acctcctcca ttaaggcgtc gacatcagct
    10081 gtctcctctg ccatagacat gtaaatggca ttgatacgct cctctgtttt gaatagctca
    10141 tcaaaggctg tcctaagaac atcacgcaca gtttgaccag gttctaaaac ggtatgctga
    10201 tccaaatagc ctgctgtaac atactttgac cattcaatct taccagcatc aggctgcaag
    10261 tgaccagtaa caatactcat aaaggtggac ttgccttctc catttgctcc tactaatcca
    10321 atatgctcgc cctttaaaag acgaaaggaa acatcttcaa aaatggcacg atcaccaaat
    10381 ccatgactta actgcttaac ttctaatatg ctcatgatta ctttccttta ttgtcatcaa
    10441 aaaagccgtt aaaacggctt acactctctc aattatggca aaaatgcagc cttttgtcaa
    10501 tgaaggctga aaaagcctac gtcatacgca tgaaagattt ttagcaagaa cagaaggttt
    10561 tttgcatttt aatgttcagc tatttcaaat atgtcttatt attttataaa ttttactata
    10621 gggaaagcct tgaaagtgcc tgctttaatt tatactatca ttcggaaaga actgtttcgc
    10681 tcgtttgttg tggaaagccg ctcacaacaa agacatagag agtctatgac aacaagagct
    10741 acactttagc aagtcttgac cgacatgctt tattgcccag tctaattcat taaaaagcga
    10801 acaggtctag ctttcggaat ttcagaaaac taggcctgtt catttgttct attttgaggc
    10861 agccttttgt ttcggcctcg tctgtttcaa ggttttcaga tcgaacttaa ggacaaaaaa
    10921 cactctcctg tatcagctaa ccttatcatt cattataaag gaaaatgatt tctaatacaa
    10981 ggaaataccg ttatttcatt aaaaataact aaaaatagtt tgtcaaatca ttagttatta
    11041 ataggcttag ataacaaaaa tgatgatact gctagcaagg ttagctcaac caagcctatt
    11101 actcgcttct tgctttttta ctgcctgcct taattgctta aaaacagggt ataagagagg
    11161 cacagcaata acggtcacaa gggcagtacc aagactgcca ccaattttgc caagtgctgc
    11221 ccacaaagca acagacaggg gtaactgggc gccaaaataa gcaatcaagc tatatttcac
    11281 aagattcatg actaattttg ctgctgctgc taataagcca attgctacaa taatcatcgg
    11341 tttatcaact gatttcagaa gtttctcata aatcacatga agcaggtaac aaaccactaa
    11401 ggcttcaagc actgttatcc agaccacagc cgcatagcca ttaatcatat caaacagtcc
    11461 tagaccaatg gctgccacca aagctgccct tctagcacca tacaataaaa cagccaccac
    11521 cactaaggca ttccctaggt gaataaattg ggctccaact ggaatacgca gcagctcaac
    11581 cgatataaaa ataagagcag caaataggct aagctcgatc tgatcagtca atcgttttga
    11641 tgtcatcttt ttcctccaat aatcctctaa acgcggctcc caagctgccc aattctactt
    11701 cgtaggcaat tccaagtgaa agctctcgat ttagcgcaac agtagccgct aatgacttgt
    11761 ctaagaagct aataaccata tccaacaact catcaatagc aagcctgtga aaatacccag
    11821 cgctaacaat agcagagaca agatcacctg tcccatagaa atgataaggg taccgttttc
    11881 caaaatgata gctaaccgtc tctgttgcct tttgataata agcaaagccg atgtgctgat
    11941 catcaaagga tataccagta aggacaatct ctctaggtcc tagtgtagct agcttagaca
    12001 atagcctctc caaatcctct ctgctatagg tctccccaaa ataaggaaca tcagctaaca
    12061 aacaagcttc cgtcacattt ggcaatatca gctgtgcagc ttgagcgagc aatctcattg
    12121 ccgataagtg ctgcgaggtt aactgcgcat acatgcttcc cttgtcagcc ataataggat
    12181 ctagcacaaa gggaagctgt tgctttttga tgtaatcaag aataatcaaa gcatcatcag
    12241 gacggtacaa ataaccggaa aaaaagccat caaaggcaag acccgcttga gaccaagtcg
    12301 tcaaaaatgg ctttagtccc tctgacgtgc tctgaatata aggcgtctta gcaattgcag
    12361 tgtggcttga taacaaacag gttggaagaa tggcctgttc aatctggcaa gccgccataa
    12421 tgggaatact agcagacaga gcaaccttgc caactccgac aatatcattt gcaacaataa
    12481 cacgttttaa caaccaataa gctccttcat ttcttttttt actattgtaa gaaaatcctt
    12541 gatgagatac aataaggata gatttcatct gtatggggac acttatgaca agtaaatatc
    12601 aacaaatcat tgcagaccta gagttggcca tgcaatcaaa ccaattcaaa aagggagaga
    12661 aactcccttc tattagacaa ttaagtcaac agtatcactg cagcaaggat acagtgcaaa
    12721 gagcactttt agccttacaa tacaagcgcc tcatttatgc tattccaaaa agtggctatt
    12781 atgtgcttgg taaaattgag gaaaagcagc attcctttga gctaagcctt gaggattata
    12841 atcagttggc ctatgaggac tttcggctct gtctaaatga agccctagac ggtaaagatt
    12901 ctgatttatt taactactat cataaggctg agggacttga ggagctgcga gaggctttgc
    12961 tgccttattt ggctgataat gggatttacg ctaacaaaaa tcagctgcta attacctcgg
    13021 gtacacaaca ggccctttac attttagctc aaatgagatt tcccaatggc cgccatcaca
    13081 ttctccttga gacaccgacc tatcaccgaa tggagcagct agcgacttcc ttaggcttac
    13141 cctatcaaac cattgaacgt gatgtcaacg gtatcaatct tcatcagctt gaaagcatct
    13201 ttaaaaccgg acaaatcgct tttttctata ctatttctcg attttcaaac cctcttggcc
    13261 tctcctacag caaaaaagaa aaggaaagca ttgttcggct ggcagagcaa taccaggttt
    13321 acatcgtaga ggacgattat ctaggggact ttgcatcgca tagtgagctt ccgctacact
    13381 actacgacac tcaacaccgg gtcatttatc tgaaatcatt ttcaatgagc gtctttcctg
    13441 ccctgcgcat tggagccttg cttttacctg atgatctcaa ggaaggcttt ttgttacaaa
    13501 agtcaatgat tgaccttgat accaacctga tcatgcaaaa ggcactagca ttatatttag
    13561 caaatggtat gtttcaaaaa aacctaaagc aaatgaggca atttttcaac aatagagcgc
    13621 ataacttact agattttcta caaaaacacc ttcctaacct agcttatcag ctcactcctc
    13681 aagcactgat tattcaatta gataaagcat tcaatcgcaa aaagcttctt aaaccacacc
    13741 acacccaaat catctcaaca agaaaagcaa ggtatatgct tctaacaatc agtcctgata
    13801 tgccatctaa gctgctcgac ttgttttcag tgacacatga aaagacccaa gaatagctca
    13861 ttgggtctca gtgtcacaaa aatgtcaata gctatttgat ttgctcgaat cgtaaatgaa
    13921 cactaatgct atcgccgtaa ccgtttctct ccaaatctct ttggagccgg taagcaatat
    13981 aatgctctgc aatagtcatg tagcctgcgt caatcagacg attttcaaca agtgattgaa
    14041 tcatattaat cgtcggacgc tccgcctgca cctcttctag atcaataaca acctttttag
    14101 ttacctgagc tagatgctgt ctccagctgt catcaatcac ataaactgtt cttgctgcct
    14161 tgatcaaagc ctgataaatc ttatccggat caaagtctgc cagctgaccg tcacgcttaa
    14221 taatttgcat aagagcgcct cttttcattt agtttcattg cttacattca ttatgcaaat
    14281 gttttcatca tttgtcaagc tattaggctc ctatgcctct tagggattat cagtcaaaag
    14341 aaacactagg atcaaataaa ttgtcctgtg ctggtcggac aagcccacgc tcgtgcaagg
    14401 tctctgcaat ctgaacagaa ttccaggctg cgcccttgag cagattgtca gataccaccc
    14461 acatgtgaat gcccttttca acatctaaat ccttacgaag ccttcctaca aaggtctcac
    14521 gactgccaac agcattaacg gcctgtgggt atcgttgcac tccggtatcg tcctctaaaa
    14581 cagcacccgg aaattgtgca atcgcctcct taacagcttc gatagtagct actgccttgg
    14641 tttcaatgta gatagattct gaatgggctg ataaaacggg tatacgaaca caggtcgcag
    14701 acaccttaat cgtatcgtcc tccatgattt ttttcgtttc atttgtcatt ttcatctctt
    14761 cataggtgta gtcattttca gtgaaacgat caatctgtgg taaagcatta aaagcaattg
    14821 gataatgtct cttgtcacca gctgacggta aaacacttgc ctccacctcc ttaggagaca
    14881 agccctggtt aataacctgg tcatactgag ctagggtctc acgaatcgct gattgaccag
    14941 cacctgaaac agcctgatag gtggaaacaa taatacgctc aagaccccac ctttgacgaa
    15001 taggctccag cgctatcatc atttgaatcg tagagcaatt agggcaagca acaaggcctt
    15061 gatgtgtatc aagagcgtga gcatttacct caggaacaac aagtggaaca gctgggtgct
    15121 gacgaaaata agaggtattg tcaaccacaa cagcacctgc cgcaacagca taaggggcat
    15181 attttgcaga aacattgcct cctgctgaaa aaagggctag atcaatgcct tggaaggctg
    15241 cttttgttag ctcctcaaca acaaaatcct ctcccttaaa tgagaggatt tttcctgctg
    15301 aacgtgcaga cgctaataat ttaatagctg aaataggcag acttgactcc tccagcatct
    15361 taatcatttg ctgaccgaca gcgcctgtcg ctccaaccac tgctactgta taccccatag
    15421 atcgacctca ctttaactga tgatattgca aaaaatgata ttggacctat tatagcctat
    15481 ttcatcacaa aagaaaagca agctagaagc cagaacaaac gcatgaagaa aatcatttat
    15541 tgaaaaagtt gtgaaaatag caaaatatcc attttagagt attttgacag agtgtttcct
    15601 gaatttttat atttttcctc tataaacttt tcttgaaaaa
//
LOCUS       DARYLJ010000046        15190 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYLJ010000046 DARYLJ010000000
VERSION     DARYLJ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15190
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(262..465)
                     /locus_tag="TU746_001558"
     CDS             complement(262..465)
                     /locus_tag="TU746_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL0891877.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(482..736)
                     /locus_tag="TU746_001559"
     CDS             complement(482..736)
                     /locus_tag="TU746_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0891878.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(1478..1774)
                     /locus_tag="TU746_001560"
     CDS             complement(1478..1774)
                     /locus_tag="TU746_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0891879.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(1781..2029)
                     /locus_tag="TU746_001561"
     CDS             complement(1781..2029)
                     /locus_tag="TU746_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL0891880.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            2289..4445
                     /locus_tag="TU746_001562"
     CDS             2289..4445
                     /locus_tag="TU746_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL0891881.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            4456..5814
                     /locus_tag="TU746_001563"
     CDS             4456..5814
                     /locus_tag="TU746_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL0891882.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            5914..6045
                     /locus_tag="TU746_001564"
     CDS             5914..6045
                     /locus_tag="TU746_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0891883.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(6167..7501)
                     /locus_tag="TU746_001565"
     CDS             complement(6167..7501)
                     /locus_tag="TU746_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0891884.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(7501..8250)
                     /locus_tag="TU746_001566"
     CDS             complement(7501..8250)
                     /locus_tag="TU746_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0891885.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            complement(8877..9080)
                     /locus_tag="TU746_001567"
     CDS             complement(8877..9080)
                     /locus_tag="TU746_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL0891886.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(9097..9354)
                     /locus_tag="TU746_001568"
     CDS             complement(9097..9354)
                     /locus_tag="TU746_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0891887.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TU746_001569"
     CDS             complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TU746_001569"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL0891888.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(11039..12007)
                     /locus_tag="TU746_001570"
     CDS             complement(11039..12007)
                     /locus_tag="TU746_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0891889.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            12071..12847
                     /gene="recX"
                     /locus_tag="TU746_001571"
     CDS             12071..12847
                     /gene="recX"
                     /locus_tag="TU746_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL0891890.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            13080..13613
                     /locus_tag="TU746_001572"
     CDS             13080..13613
                     /locus_tag="TU746_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL0891891.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            13863..14174
                     /locus_tag="TU746_001573"
     CDS             13863..14174
                     /locus_tag="TU746_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL0891892.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
BASE COUNT         5007 a         3376 c         2397 g         4410 t
ORIGIN      
        1 atatgacagg ctacaggagt atcattcttt aaatgttaac aattgctaaa atttcgatat
       61 taggtctatc aatatcataa tataaaggat aaaaagaaac attaagttgt catgagctaa
      121 aaataacaaa aaaaagctat ttatcgttga tatatcaaca atgtcattat ttttatctaa
      181 acctctcaca gatctataga taaaataaat ttgaaaggtg aaaataacta tagtaaatat
      241 atatttcaga ttcatatcat attatgatga agccttatag gctaaataac cacaaacagc
      301 tgcacttcca actcctccga taacagctcc ccaaggtcca atcctacttc ccaactttat
      361 acctccaaca gcacaggtca aaccacctac tactgctgca ccggcagggt tccctccaca
      421 aatgtcgtta agttcttctt ctttgatttg ataataatga gtcataaaaa acctctcttg
      481 attaaaatcc acctgttgct cctgttactc ctgcccacaa tgatacgcca aatttggctc
      541 caatgtaacc acatgctccc ataaatggag caccggcacc acttgcagca caaatagctg
      601 tccctaaccc ccagccacta acagcagcgg taccaccttc ccaaacatta gcttgccaat
      661 tattctttcc accttcaatg tgagcaagct tgtcagcgtc tataatatta aattgtttca
      721 ttaatgtcgt attcatcgtg aatacctcct atatttattt tttgtctgct gcaactgaca
      781 aacccagtat agcagataaa caatcgcttt cagtatttaa gtcttaaaat gtcgtcgaaa
      841 cgtcttgaat ggtaatacga aaaccgttaa caccaattca gtgaaaattc ctaataccca
      901 taacaaatat gagaaagctg tcttaattgc ttcaaaagct gagtttcctc ctttgacggc
      961 tgaaggctct atgctgtaat gacaaatagc ccaatcttaa atgactattt tatttttcca
     1021 gatagcaata catcatcaac agctgatgaa aataatacat ttgtggcctc agcttactaa
     1081 cttaagcctc tagaaataag gaaaagcaac tgatttgata gctaatagcg cagataatat
     1141 ttcttttcca agctcaataa gactcaaaaa taagttcttt gtaagaaaaa ataaatcact
     1201 aaccaaatga gataagctta ttgcccttgc aattatctca agctacttct tgtccgaaac
     1261 caccctagat agttaactac cacaaaacaa taggtatcag ctttaaactg atacccattg
     1321 ttatatcctg cgattagcca atcaactcaa tcgttactta ctttaccttc agctagccat
     1381 ctcacaaaat agcattgaca accttttcat gtcatttggc ctattgtgac tcaacaaaac
     1441 aataacgcca atacaacgat aaggtatgag cgttttatta tcgcctaata actcccaatg
     1501 atattaggcc tctacctagc tgtttatcac attctttgta agtagagatt tctttataga
     1561 atttagccat ttctacactc attgtttcaa ctcttatctg cttaacagct aattgacgca
     1621 gagattcaga tagcatcatc acttctctgt caaagttact tgactcccct actctatctt
     1681 taaatcttac cagaatgact cgctcttctg atgttaaggt tggatctaaa attaaattat
     1741 aaaccttatt tagtatctct tcttgcgtca acatacccaa ctaccctcta taccctggat
     1801 ggaaataacc acctcctaaa gaggatatcc aaccattaac aataacatct ttagttgctt
     1861 caaaattact tttagtaaca atatagcccc attcgccatt gctatatcgg caggcatacc
     1921 cattagaacc agacattaca aacttacaaa ttcctttgcc gccaccctca atgtgagcaa
     1981 gcttgtcagc gtctataata ttaaattgtt tcattaatgt catattcatc gtgaatatct
     2041 cctatattta ttttttacct gttgcaagca acaaacccag tatagcagat aaataactgc
     2101 tttcagtatt taagtcttaa aatgtcgtcg aaacgtcttg aatggtaatg tcgcaactga
     2161 ttaaaaaaga gtgttaatat cattattccc atttaagacg tttcaacgac tattcaagac
     2221 tagctcagtt tttttctgag cttttgtggc acaatagagt cgttacaaca gagaaaggaa
     2281 gccaaccaat gacactcttt tataaaagaa cctttgtatc acaaatagat gccagagatt
     2341 gtggcgtagc tgctctagcc tcaatcgcaa ggtattatgg ttcagattat tcattagctc
     2401 atttgagaga attagcaaaa accaataagg aagggacaac agccctcggt attgtcatgg
     2461 ctgctaagga aatgggattt gaaaccagac ccattcaagc ggatatgacc ctctttgaca
     2521 tggcagacgt gccctatcca ttgatcgtcc atgtcaataa agaaggaaag ctacagcact
     2581 actatgtggt ctacaaatct aaaaaagact atcttatcat tggtgatccc gatccaatgg
     2641 tcaaggtcac aaaaatgtcc aaggaacgct ttgcttcaga atggacaggt gtcaccatat
     2701 gtcttgctcc taagccaaat tataaaccac ataaagacca aaaaaatgga ctattaggct
     2761 tctttccgct tatttttaaa cagcgaaccc ttatatttta tatcgtgtta gcttctgtct
     2821 tggtaacggt cattaatatt gctggttcat actatctcca ggggatttta gacgagtata
     2881 ttccaaatca gctgaaatct accttaggga ttgtatcaat tggtctcatc attacctata
     2941 tactccagca gctaatgagc ttttctagag attatctttt aactgtcctt agccaacgtc
     3001 ttacgattga tgtgattctg tcctatatcc gccatatttt cgaattgccg atgtcctttt
     3061 ttgcaacacg tcgaacaggt gaggtaacct cgcgctttac agatgctaac tctattattg
     3121 atgcactcgc ttcaaccatt ttatccctct ttctagacct ctctatatta gctattgtcg
     3181 gaagtgttct tttggtgcaa aatagcaggc tttttctgct atctctgatt tctatcccag
     3241 tatataccat tatcatatgt gcctttataa agccgtttga acaaatgaat catgatgtga
     3301 tgcaaagcaa tgccatgcta agctctgcta ttatcgaaga tatcaacggg atcgaaacca
     3361 taaaatcact aaccagtgaa gaaaaccgtt accaaaaaat tgacagcgac tttgtggatt
     3421 accttgataa gtcttttaag cttagtaaat ataccatctt acaagccaca cttaagcaag
     3481 gagcgcagct aattctgaat atcatcattc tttggtttgg ggctcaactg gtcattaatg
     3541 gtaaaatttc aatcgggcaa ttaattacct ttaacacact tcttgcctat tttacaaccc
     3601 ctttagaaaa tatcattaat cttcaaacca agctccaagc agctaaggtt gccaataatc
     3661 gtctcaatga ggtctatctt gtagagtccg aatttaaagc ctcgcaagcc ttatacgatt
     3721 tatcgctctt acagggtgac attcagtttg aagctgtttc ctacaggtat ggctttggca
     3781 aggatacatt atcagatatt acattaacca ttaagcaggg agcaaaagta acccttgttg
     3841 gtgtcagcgg ctcaggaaaa acaaccctag ccaagatgct cgtcaatttc tttgaacctt
     3901 ataaaggacg tataaccatc aaccaaaacg atctcaagac cattgataaa aagaatcttc
     3961 gacaatacat caactacctt ccacaacaag cctatgtgtt taatggatct atcttagaaa
     4021 atctaacctt gggagccaag caaggcatca gccaggaaga cattcttaac gcctgtgaga
     4081 ttgctgacat tcgtcacgac atcgagcaaa tgccaatggg ataccaaacc gagctctctg
     4141 atggggctgg cttatctggc ggacaaaaac agagaattgc acttgctaga gcattactaa
     4201 cccaagctcc tatactagtt cttgatgaag caaccagcgg acttgacata ctgacagaaa
     4261 agaaaatcat tgaccgtctc atgaacatga cagacaaaac gattattttc gttgcccacc
     4321 ggcttagtat cgcagagcgc actgatcaga ttgttgttct taatcaaggg caaatcattg
     4381 aaacaggcag ccaccaggaa ttaatgaaac aaggtggatt ttattaccac ctatttagtg
     4441 aataaggaga caatcatgaa tcccaatatg tttaaaagtg cggaattcta ccaaagacgc
     4501 tatcatcatt tgacaacatt cttaacaatt cccttagccc tcttgttgac ttttcttatc
     4561 cttttttctt gctttgttta taaagaaata acggtaacgt cctacggaga aatcactccc
     4621 actcaagtca ttgcaacagt ccaatctatt agcaataatc ctataattgc gaaccatctc
     4681 accaataacc agccaatcaa acaaggagac tctattattc aatatgctaa agacctagaa
     4741 gagtctcaaa agcaggtact tgagaaacaa ttagctacct acgaaaagca aaaaagcagc
     4801 cttaatactc tattgttaag cttaaaacaa ggccagaacc tttttcagaa cgatgatcaa
     4861 tttggttacg tcaatacctt taatcatttc atgagccaag cccaagatat tgaccttggt
     4921 ttctcaaaaa taaaggcaga gaccagccag caggcccagc tgattcagga ctctattgtt
     4981 gctatcaatc agcaaataaa tagtctttct caacaaatat cagactatga agagcttcga
     5041 tctgcgatca ttaaccaatc cgatagtcta tcctccaata acccacatca agccaccctt
     5101 gatgcctatc tctctcaatc tcaagcaaac caagagactg ccaccaatca gcttctattt
     5161 caaatagacc aaaatctttt aaacctaaaa acctctatag atagcctcta taggcaacgt
     5221 gctaatctac atcaatctac cagctatgat aatagcctca acacaaagct agaaatactc
     5281 cgaacacagt ttttgataac agcctctcag cagttaacag atgtcaatca tcatattact
     5341 gagctcaagg cgcaattgga gcaagccact cttcaggtaa acaatctggt gatcaaagcc
     5401 tcaaaaagtg gcattgttca gctcaatagt gcttttgaag gcaaaattag tatcccaatc
     5461 ggtcacgata ttgcctacat ttatcctagc ctcaaacaaa caaaacaagc cttgctcact
     5521 tactatgtca gctctgaatc tgtttctctc cttaagaaga accaggttgt caggctagct
     5581 ctagatagac atggaaatca accgatagtc attacgggaa ccattaaaac cattgatgag
     5641 ctagcgacca aaaccaagca gggaaatctt tttaaggtta cagccaaact aacactttct
     5701 gaaaaagaaa gcactactat tcaatatggt cagcagggac gagtgataag tgttattgcc
     5761 aaaaaaacat tctttgactt ttataaggac aagctcttta aagtgacaga ataaccattt
     5821 agcgcttttc aacgaccatt taggacatag agtacaacaa agagtcaaga taagctataa
     5881 taacatagac agtatttaaa aggagctttc aatatggata aaccaactag acaaccaaag
     5941 tttcaggaac taacgccttc tcagttaact cagattactg gaggaggctg gcttgaaggt
     6001 cttcaaaaag ttttcaatgt ctctaagcca aaactactaa aatagtaaca ttctccattt
     6061 tcaaaacacc actacctaaa ggtactgaga cactatcgga atgatgtgat cctaaacatc
     6121 aaatctgata ggtgcaagac agttttcctt tactagtggt gtttttttat aacctaagct
     6181 caagtgtttg accaaataca tgattttgac ttatagtctt aatcatcaca ttgggataac
     6241 gattgataat ttccatagca ttataaagtc ccacacctct attatccccc ttggtgctta
     6301 ctccgaaatc atatagaaag gatagatcaa tcttctcttc cttagttgta ttttcaatca
     6361 taaatagttg cttattgtcc aaagtaaagt aagaaatcgt tatcttagac gaagaagctt
     6421 caacagcagc ctctatagca ttatcacata aaatagacac aatagtaaga aaatcaatca
     6481 gctccatgcc ttgcggactg atatcctctg gaacctctaa agatactgaa atcccacttt
     6541 ctaaagcctg actaaatttt gcagctaaaa gacttttcaa ggctgtgtca gtgacatgga
     6601 taagacgccc aacatcatat ttttgcttgc gaaatcgttt atttgaatcc ttaaagaccg
     6661 attgataaac tgacctaaca atagacatgc tatcattatc tataccaaac tttaacgtgg
     6721 caatcagatt gctatagtca tgacgaaatc ctcgaacctc tctgtaaagc tcctctatct
     6781 gacgactata gctctcaata tttgccagct gcagctctct ttgaaaggtc agtctttctt
     6841 gcagtgtatc tcttagcgac cggtccagtc tcgacacagt tcccataaat ataatccaat
     6901 agccaagcat catgcattga cgataggcat aagtatcaac agctagctca tactctaaat
     6961 aagcaagcaa ttggatcaaa aaataatagc taaccataga ccagttggtc acacctaaaa
     7021 ttcttttatc cctatcagat aaaagattaa ttcttaatgc tctgaaatca tatcgtagcc
     7081 accgcaaaaa gagaaaaacc atcaaagtag atactatatc tgtaaaaatt ccccaaaatc
     7141 catcatttgt taaatgataa tcaagtttaa aaagaggtaa gataaaaaaa ccaagcagtc
     7201 ggtaccaaag gctccacagg gtaataggaa atagcccata aaatatcaat aatgtttttg
     7261 ataagggtcg cagcaatagc catgatatca ctaccatata aattggaaga ctccaataat
     7321 tgagaagtga aatgtcggca acatgattag ctatagtgaa aaaaacagca aatcctattc
     7381 ttaaaaaagt actgaaagca acttcaagcc aggttaattg acgtccactg attttggaaa
     7441 agagcactaa cgataagcct atacttgtcg tcatttctaa gaaaaataaa ataagcttca
     7501 ttaattatct cctctatgta ggttctcaat tgttgttaaa acactgttca ttttactacg
     7561 agcaattaag cagctagagc catttcgaaa ataaaccact cgctcaatct tatctaccct
     7621 aacgacattc ctatgattaa tcaaaaaaga acgatgacat tgcaaaaaac gagactcttg
     7681 cttcaaaata tccgtcaaag tccccgtaaa ttgcattctc tccttttttg tatacaaatt
     7741 gacacgatgc gctcgtgacg atgtctcaat atacaggata tcattaaaag gcacctgtac
     7801 ctgagcataa cgagatgtaa aataaaaagc actttccgct atcgtttcac tattttgccg
     7861 cacagcatat aataaagcag tctctacccg ttgaacaaac tcagtttgag gcagctcttt
     7921 atcgatatag tccaaagcag atacctgata ctgaaaagcc aagggcataa attccgagtg
     7981 agtcgttaca aaaacaatca tcgcatctgg atttatctga cgaatttgcc tagcaacctc
     8041 aagccctttt ttgttctcat tttttatctc aatatctaaa aagaatagct gctgaccaca
     8101 gttcttcttg atagcactta atagctgatg aggccttcca aaacagtcaa gtccttgaaa
     8161 taatagctgg tgcttaacct caagctcttt aatgagcttt tctaaatatc tctgctgaat
     8221 catatcatct tctaaaataa ctactctcac ctaaactcag tcccctatcc aatctgcaga
     8281 agcattagca ctactaccgt ttcaacaaaa taataagcac aataacaaaa ataaatccat
     8341 taaaaacaac tgcatcaaaa ctcataaaaa taatattttg tacttatttt agcataaaat
     8401 accatttttg aatacactaa tctctaataa actaatgcta tctagtctta gctagcaata
     8461 acctagtgct tctaacaaca ataatcagct caacaatttt tagcagctac ctttttaaaa
     8521 aaactgggat aaaaagattt ctcaggtaag aaaaatagag attcaccaaa cagtgaatct
     8581 ctattttttg aactgaaact ccttttgtcc caaactcata agatgtattg actttatgag
     8641 atgaacaatt tgttacactt gatttgatca tcggggttta gaaaaaatag tgaaaagaat
     8701 cctcataatt cgtgaaaaat ataatttctc acccaaaaat ccaattcaag attgtattta
     8761 taagaagtag catgattaaa gttatagaaa ttcttatcaa cgcttcttct tttttaacaa
     8821 caccaaatat caatagtata atcggaacta aaactaatac tactaataat attgttttat
     8881 aatccattga taatggcctg tcctgcacca acaatgcatc ctattcctgc acccaataca
     8941 tacaatggac cagagaaagc acctgtaacg attgctccac ctgcacaatg ccctgcaaca
     9001 gagccccaat taattttacc gccatttaca cttgccaaat caagctcata taacatctga
     9061 aaatcttcgt actgcttcat ggtatatact cctttcttag ttaaatctat tacctatcat
     9121 tccacccatg catgcaaaac ctcccccaat tgcaccaaca tgtgcaccaa caaatgcacc
     9181 tggaagtacg ccaatccctc ctgctggggc accccacaaa gccccacttc cagctcctat
     9241 taacatatat cctcccatgt ctttaagaca gtccttacca gaatatccac cttcaacagt
     9301 tgcaagagcc tctatattca taacatcaaa ttgattaatc gtttctgtat tcattttgaa
     9361 tacctccata acatattttt tctttatgtc gcgatcacga tttaagtata gcattctagt
     9421 atcatatttt ttctaaaagt cttaaacggt cgttttttca tcgtaaacgg tcattttcaa
     9481 tcgttttcaa ccgttcaaga caaaattaac taccattcag gattttcatt ggataaatag
     9541 ctattttttg gctctttgcc aacccactaa agctattaat aaaaaaataa gacagtagtc
     9601 acatttaggc tactgtctct tttatctaaa gccttgatcg gtaagaaaag agccagtctt
     9661 ttccaactaa tcgattattg ttgtggtttt tgtcgctttt gtagcttcac tacagcctcg
     9721 gtccttgctg tgtgtggaaa catgtcaaca gattgaatat atatcacatc atagacctga
     9781 accaagggta ccagatcacg agccaaggtt gaggtattac aggagacata aaccatttta
     9841 gctggctgat agtgtaaaat cgtttgtaat agcttgtcat ctagtcctgt tcgaggtgga
     9901 tctacaatca aggcatcagc tcggtagcct tcagcgtacc agcttgggat cagttcctct
     9961 gccttgccag tctcataata agcattgtca aagcccaatg cctgcgcatt tttcctagca
    10021 tcagcaattg cctctggaat aatatccata ccacgaacag atcttacttt gtttgcaact
    10081 gccagaccaa ttgagccaac accgcaataa gcatcaataa tatgctcctc agctgtgggc
    10141 tcaagcgcct gaaccacttg actatataaa acctctgtct gtgtgggatt aagctgataa
    10201 aaggctcttg gcgacagggc aaagctatgg ctcaaaacct cctcttgaat ggtctcctga
    10261 ccccagagaa tctcagtttt ggcgccataa atatcactcg tttttgaagt attgatgttt
    10321 aaagcaacag tcctgatttg tggaaatgca gcagtcagct cagcaataag acctgccagc
    10381 ctcacctctt tactgcttac aaaaatcaac tgaacctgat cactggcctg tgccctacga
    10441 accataactg tacgaattcc agctactctg cgttcattat agataggaat cctataccga
    10501 tcaagcagct gagtcacatg attaacaatc gcctgtgtta gctgatcctg aaccagacaa
    10561 tcatcaatgg caaccaagca atggctccct tctgaaaata agcctgcctt gacggagcca
    10621 ccaaacgaac gcgtctgaaa ctgtaatttt gctcggtaat gctgcggctc tgccattcct
    10681 aaggtatgac gaatctcaaa ctcttcatac cccttaggct taaacttttt taaggcctgc
    10741 cgaatgatgt catccttaaa gtagagctgc ttaggatagg ccagatgcat gatttgacag
    10801 cctccacagg tctcataaat ggaacaggcc ggcttcaccc ggtttttaga agccttatta
    10861 atcaccaaga gccttgcctc agcaaaattg cgcttaacag cagtcacttg acaaaaaacc
    10921 tcttctccct tcaaggctcc gggaacaaag accaaggtct ttttataaaa accaattccc
    10981 tcaccattaa tccccattcg cttaatctta agcggtattt tttgctttat tttgacattc
    11041 attcctgact aaatattact cctaatcgct taagccttgc tatcatctgc ttgccaacac
    11101 ctggaatatc aagaagctct tgagttgtcc aggccgaaaa atcctccaga gtatgaatcc
    11161 catactgatt aaacaaattg accttactta aaggaagatc aagctcctct agaaatgtta
    11221 gctcgccttc agccccttca aaaaattcct gaacataatg ctgcaggtaa tattgtgcag
    11281 tcatcaatag cggtaggata ttaaaaaagg caaggtaaat acttgataag ctgtttggct
    11341 cgtagctctc cagggcacca gcagctaaaa tatcatctat cggaaaggct ttctgtctga
    11401 caattgccac aaagtctggc accgtctcag caaggttagc caaaatatca tcagctagct
    11461 cttctctttc agctaatagc gctccaacca tcaaaggaac ctccatcaac agatctcctc
    11521 tatgataatc cttactgtca taaaaagcct ctgccatcgt aaaatcagac tttaacacat
    11581 aaagagctaa gatttcatac cttgtcccta agtgatcccc ttcatcgtat tgatgaattt
    11641 ctaagaggtg atgtaaagct ttttcataaa gaccattttg cttatacagc atcgccagct
    11701 caaatttttg agacaagtaa ggtctctctt caagattcac ccatcccata ggcttagaag
    11761 caagccaggc ctgatgctga cagtcttcat caaaggccaa atacttgatt aagtcatagg
    11821 ctctatctcc tgcaaagtgc tccaagtccg acaacaactg gttatccatg ctgtttaaaa
    11881 gagcctctaa gtcatcactg aaaaactctg tctcatgtcc aaagagcata tcatcttctg
    11941 catcagcttg gcgatagtgc tgtaagctaa caaccttatc tctatctttt ttatcttttt
    12001 ctgtcataat gccctttcaa tctattgacc atttatactc ttattttacc atttttgtta
    12061 taatgagggt atgaaaatca gtcaaattga aaagaaaaag catttatacc tcattaagct
    12121 agacaatggt gatagcctaa cggtcacaga agatacgatt gtcacattta tgctaagtaa
    12181 gcacatggtc atagacagcc aacaatggga ggacatcaaa agcttcgcac aattctcata
    12241 tggtaaaagc aaggccttag gttttattgc cttccaacaa aggagccaaa agcaagtcca
    12301 agattacctg ctaaagcatc agattagtcc tgatctcatt ccaagcatta ttgatagcct
    12361 aaaacaaggc aaatggattg atgatcagca atacgttgac acctatatac gccaaaatag
    12421 ccttactgga gacaagggac cattacttct caagcaaaag ctaatgctca agggaatagc
    12481 ctcacaactc attgagcctg tcctagcaca gactgatttt tcctctatag cacaaaaggc
    12541 tgctgaaaaa atctaccaga aatatcaaca caaattgcca agtaaggcct tgaccgataa
    12601 aatcatacaa ggacttctta acaagggctt ttcctatgac cttgccaaag gcattgtcag
    12661 tcaactaagc cttgagcagg atagtcagca catcgaagac ctgcttgatc aggaattcga
    12721 caagctatta cgaaaataca gtcgtcgcta tgatggctat cagttgaagc aaaagcttta
    12781 ccaagccctt taccgcaagg gctatgacag tgatgatatt accactaagc taaatgacta
    12841 tttctaattc taccaaggct gctgcaccga tttgacgcaa aagcttttag tcagcaacaa
    12901 agtagtccta ttatgatcct gtagctttga taatggttta gctagctcct caactgaaca
    12961 tcagatttct aaaaacttct ttaagcattt gtcagatcat attgtccaaa acagtgattt
    13021 attttctcaa ttatggtaaa ctatagagga taagtttaat tgtagaaagt tggtaaggca
    13081 tgaaattacc taaagaaggc gactttatta caattcaaag ttataagcat gatggtagat
    13141 tgcaccgaac ctggcgcgat actatggtac taaaaacaac tgaaaatgct ctgattggag
    13201 ttaatgatca cacacttgtt actgaaagcg acggcaggcg atgggtgaca cgagagcctg
    13261 cgattgttta ttttcataaa aaatactggt tcaatattat agcaatgatt cgagataatg
    13321 gtgtttccta ttattgcaac cttgcaagtc catacctgat ggacgcagaa gcgctcaagt
    13381 atattgacta tgatcttgat gtcaaagtct ttgcagatgg tgaaaagaga ttgcttgatg
    13441 tagacgaata tgaaatgcac aagcaagaaa tgcattattc acctaatctg gattttattt
    13501 taaaagagaa tgtcaagcta ttagtcgact ggatcaataa agaaaaagga ccattttcaa
    13561 aagcctatgt cagtatttgg tacaaacgtt atcttgaact gaagaatcgt tagtcgttgt
    13621 ctagcactcc accgagggtg ctttatttaa tcgctagtat agtatcacag ctgtaaactg
    13681 gactggcact tgcaatctat cagcatttgt tgtcaaattc atatcattaa ccactatagc
    13741 ttggcacaag cacagacagc ctataacacc aagtagcaat cagtatttat catcagctgc
    13801 ctagctagat caggcattca aatgacctca ttataacacc ataacaatag aaaggattga
    13861 caatggcatt tcaagcaaca aaaggacgat acgcaagctt tggcgttgca gtcagccttc
    13921 cacctgagct gattgatacc ttctgggaaa tcattgacca ttacctaaaa ggggtgtttc
    13981 ccctcaatac tgttctcacc ttcaggctaa ttaaaaataa aaaaaacctt tcttatgagt
    14041 acattgatca acaagctggg cttcggattg tttttgacta taacacacca tttaacgcct
    14101 tttaccccaa aacgctctat atcgtaaacc agcaaggaat tgaaacgatt ttattgcctc
    14161 acgagatgta ttgataagac ctcggacatc agctataaag tccttaccat tcagttgtag
    14221 ctcatcacat ctgctacaag caccaacatg agataatctt gtgtctttat cctagctctg
    14281 aatgctgtat agatattcag tcagccagat acatagcaat aaactaagct catgccggta
    14341 gaaatagtcc taacatgagc ttgacagttt tttcattctg taaatcattg ctaagcaaac
    14401 acatcaccta agccctattt cctattctgg gaaatggaaa tcttgataga acatcccaat
    14461 agtcccatca tattgagcta tatctatagg gtctgacatt ttgatatgtt atcatctcat
    14521 tttacgacaa tcactatagg ctttatgaca attggcatca ttgtcataac gattaaattc
    14581 tatatgacca aatggctagt aggaagctaa ttgctttgtg ttagcctcac ataggatctt
    14641 cacatacccc gtaatcttaa aagtagtttt aactgcacaa aacttataga acctaaaaat
    14701 caacaaacac actttaaagt acaaaaactt tgccctccct caaaaagctc tataatctct
    14761 gtagtcggta agcccactgt ggaaattata gtttttttaa ttgtacaaaa acaagcccat
    14821 atgacttatc atgaaatgca atcaaaccat cattagaaag actcatagga acaccttaag
    14881 cattactcag catttaaaaa acaatatcca accgttgact gttctaaaag ctcaccccca
    14941 catcgttatc aatcctaagc ttgattattc agttctctta tgccctcact acaaaggaaa
    15001 catgagcaaa caagacttcc aaaaagcctc taaaatccct atcttcgatt gccaaagctt
    15061 tccaacactg cttcaactca aaaaacactg ctttcagtgg aaagccagtt ctaaagtgag
    15121 ccttgctcaa actccttttg gttttaacat cacaaaaaag agcaccaatc tggtcctctt
    15181 tagacgttag
//
LOCUS       DARYLJ010000047        14068 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYLJ010000047 DARYLJ010000000
VERSION     DARYLJ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14068
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            129..689
                     /gene="ahpC"
                     /locus_tag="TU746_001574"
     CDS             129..689
                     /gene="ahpC"
                     /locus_tag="TU746_001574"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL0891893.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            710..2242
                     /gene="ahpF"
                     /locus_tag="TU746_001575"
     CDS             710..2242
                     /gene="ahpF"
                     /locus_tag="TU746_001575"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL0891894.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            2703..3473
                     /gene="rpsB"
                     /locus_tag="TU746_001576"
     CDS             2703..3473
                     /gene="rpsB"
                     /locus_tag="TU746_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL0891895.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            3641..4681
                     /locus_tag="TU746_001577"
     CDS             3641..4681
                     /locus_tag="TU746_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL0891896.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(4881..6776)
                     /locus_tag="TU746_001578"
     CDS             complement(4881..6776)
                     /locus_tag="TU746_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL0891897.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(7328..8260)
                     /locus_tag="TU746_001579"
     CDS             complement(7328..8260)
                     /locus_tag="TU746_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL0891898.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            complement(8257..9114)
                     /locus_tag="TU746_001580"
     CDS             complement(8257..9114)
                     /locus_tag="TU746_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL0891899.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            complement(9117..10460)
                     /locus_tag="TU746_001581"
     CDS             complement(9117..10460)
                     /locus_tag="TU746_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL0891900.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            complement(10473..10760)
                     /locus_tag="TU746_001582"
     CDS             complement(10473..10760)
                     /locus_tag="TU746_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0891901.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            complement(10762..12804)
                     /locus_tag="TU746_001583"
     CDS             complement(10762..12804)
                     /locus_tag="TU746_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL0891902.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            13327..13917
                     /locus_tag="TU746_001584"
     CDS             13327..13917
                     /locus_tag="TU746_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891903.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
BASE COUNT         4352 a         3178 c         2768 g         3770 t
ORIGIN      
        1 ctaaattcac atatgaaatt gttagaaaag aacatcaaaa accttgataa atctagggtt
       61 tacaagtgga cagataagat ttcttagctt ataatacagg tatcaaatgt aaaaaaggag
      121 gacatgacat gtctttagta ggaaaggaaa ttgctgaatt ttcagcccaa gcttttcaca
      181 atggaaaatt tatcactgta actaatgagg atcttaaagg gaaatgggca gttgtttgct
      241 tctacccagc agacttttct tttgtttgcc caacagagct aggtgacctt caagagcaat
      301 atgaaatact aaaatcttta ggtgttgagg tttattctgt atctactgat acacactttg
      361 ttcataaggc atggcacgat gattcagatg ttgtcggaac aatcacttac ccaatgattg
      421 gtgacccatc acatgctatt tcacaagcct ttgatgttct tggtgaggat ggacttgctc
      481 aacgcggtac tttcattatt gatccagatg gtgttatcca aatgatggaa atcaatgctg
      541 atggtatcgg acgtgatgca agcagcttga ttgataagat tcgtgctgct cagtacgttc
      601 gtaagcaccc aggtgaagta tgcccagcca aatggaaaga aggggctgaa acactaacac
      661 ctagccttga ccttgtcggc aaaatttaag caggcaaagg agaaaagcta tggcattaag
      721 tcctgatatt aaagagcagc ttgctcaata ccttaatctt ttggaatctg acttagtcct
      781 acaagcttat cttggtagtg acgatagctc acaaaaggtc aaggacttca ttgaagaaat
      841 tgctgccatg tcagaccgta tcactgttga ggagactacc ctaacacgtc aaccaagctt
      901 taagattacc caaaaaggtc aagacagcgg agtgatcttt gctggactgc ctctaggtca
      961 cgagtttgcc tcctttatcc ttgctctatt acaggtttca ggacgtgcac caaagattga
     1021 gcaggatatt attgaccgca tcagggctat tgaccgtcct ttaagctttg aaacctatgt
     1081 cagcttaacg tgtcataatt gcccagatgt ggtccaagcc ttgaacatta tggctgttct
     1141 taataagaac atttcacata ctatggttga gggtggtatg ttccaagagg aagtcaaggc
     1201 aaagggcatc atgtctgtgc caactgtctt tttgaatgga gaagaattca cctctggtcg
     1261 cgccactatt gagcagctgc ttgagcaaat cgcaggacct ctatctaagg aggcctttgc
     1321 tgataaagga gtctatgacg tccttgtcat tggtggagga cctgcaggaa atagtgctgc
     1381 catctatgct gctcgtaaag gcttaaatac aggtcttttg gctgagacct ttggtggtca
     1441 agtcatggaa actgtaggta tcgaaaacat gataggaacc ctgtatacag agggaccaaa
     1501 gcttatggcc caggttgagg agcatactaa atcctatgat gttgacatca tcaaagccca
     1561 gctggctact tcgattgaga aaaaagacct tgttgaggtt actcttgcta atggcgctgt
     1621 cttgaaggct aaaacagcta ttctagcgct tggtgcaaaa tggcgcagta tcaatgttcc
     1681 tggcgaaaat gagtttaaaa ataaaggagt aacctactgc ccacactgtg acggtcctct
     1741 ctttgaagat aaaaacgttg ctgttatcgg tggtggtaac tctggacttg aggctgcact
     1801 tgatttagct ggcttagcta agcatgtcta tgttcttgag ttcttacctg agcttaaggc
     1861 cgacaaggtg ctacaggatc gcgctgctaa aacagacaat atgactattc taaaaaatgt
     1921 tgctacaaag gatattgttg gggacgatca tgtcacaggg cttaactata tcgagcgtga
     1981 cagcaatcaa gaaaagcatc ttgaccttga aggagtcttt gtacagattg gcttggtgcc
     2041 aaatacagct tggctcaaag acagcggtat cagcttaacc gatcgtggcg agattattgt
     2101 tgataaatat ggttcaacca atattccagg tatctttgcc gcaggcgact gtacagattc
     2161 agcctacaaa caaattatta tttctatggg gtcaggtgct actgctgcta ttggagcatt
     2221 tgattacctg attcgtcagt aagttagcaa aaaaccaagg taactgttta ccctggtttt
     2281 tgctttttag aggcctaata aacagcaagg ctgatagatc aagcatttgg ggtacgccaa
     2341 atgcttgaag aaacttatgt tctctgatat cttttcatga ttcatgtgtt ctttttcaga
     2401 aagattgata gtaaaactaa gctgcgcttg aaaaatggat cgtgtcaaaa cgtcaacata
     2461 tcaaaaatgc attgaaaaca tgcatatggt tagaaaataa tggcatgcat tttcctcatg
     2521 cgtacgacgt gggttttagt gtatttaggc ttgctatgac tagctttttt tggtatactg
     2581 ttgtagttgt gcagacaaca aatactcatc ttagatcgat tgtgattctg ttgccatcag
     2641 gtggagttgc aagccgacgt ctaagagagg aaaaaaacat ttctataaag gagaaactac
     2701 tcatggcagt aatttcaatg aaacaacttc ttgaggctgg tgttcacttt ggtcaccaaa
     2761 ctcgtcgctg gaaccctaag atggctaaat acatcttcac agagcgtaac ggtatccacg
     2821 ttatcgactt gcaacaaact gtaaaattag ctgatcaagc ttacgagttt gttcgtgatg
     2881 cagcagctaa tgacgctgtt atcttgtttg ttggtactaa aaagcaagct gctgaagcag
     2941 ttgctgacga agctactcgt gcaggtcaat acttcatcaa ccaccgctgg ttgggtggaa
     3001 ctcttacaaa ctggggaact atccaaaagc gtatcgctcg tttgaaagaa atcaaacgca
     3061 tggaagaaga aggaaccttt gaggttcttc ctaagaaaga ggttgcactt cttaacaagc
     3121 aacgcgcacg tcttgaaaaa ttcttaggtg gtattgagga tatgcctcgt atcccagatg
     3181 tgatgtacgt tgttgaccca cacaaagaac aaatcgctgt taaagaagct aagaagcttg
     3241 gtattccagt tgtggcaatg gttgatacaa atgctgaccc agatgacatt gatgtgatca
     3301 ttccagctaa cgacgacgct atccgcgctg tcaaattaat cactgctaaa ttggctgatg
     3361 ctgttatcga aggccgtcaa ggtgaagacg cagaggttgc atttgaagct gatactcaag
     3421 cagagtcaat cgaagaaatc gttgaggttg ttgaaggttc aaacgaagct taagtcaggc
     3481 ttattgaact aggatagctt cttgctattc ataacatggt ctaacggggc aaagcattcc
     3541 gctctatctc gttatttttt aagtaagaaa acccagcagg tcaaaggctc tgctaaagcg
     3601 agctttaaga ggaccgattc taattttgga ggaaataaaa atggcagaaa ttacagctaa
     3661 gcttgtaaaa gaattgcgtg aaaaatctgg tgccggcgtt atggacgcta aaaaagcact
     3721 tgttgaaaca gatggcgaca tggaaaaggc tattgagctt cttcgtgaaa agggtatggc
     3781 aaaggccgct aaaaaagctg accgcgttgc tgctgaaggc ttgacaggtg tttatgttaa
     3841 tggtaacgtt gctgctgttg ttgaggtcaa tgctgaaact gacttcgttg ccaaaaacgc
     3901 tcaattcgtt gaattggtaa acgcaactgc aaaggctatc gcagaaggta agccagctaa
     3961 taacgacgaa gcacttgctc ttatcatgcc ttctggtgaa acacttgctg atgcttatgt
     4021 caatgcaaca gctacaatcg gtgaaaaaat ctcattccgt cgctttgccc tagttgaaaa
     4081 aactgatgac caacactttg gcgcttacca acacaatggc ggccgtattg gcgttatcac
     4141 tgttgttgaa ggcggagacg aagcacttgc caagcaagta tcaatgcacg tcgcagctat
     4201 gaagccaact gttttatcat acactgagct tgacccacaa tttatcaagg acgagttggc
     4261 acaattgaac cacgctattg agcttgacaa tgaatcacgt gcaatggtta acaagccagc
     4321 acttccattc ttgaaatatg gttcaaaggc tcaattatca gctgacgtga ttgcgcaagc
     4381 tgaagaagac atcaaggctg agcttgctgc tgaaggtaag cctgaaaaga tctgggacaa
     4441 aattatccca ggtaagatgg atcgcttcat gcttgataac actaaggttg accaagccta
     4501 tactcttctt gctcaggttt acatcatgga cgacagcaaa acggttgaag cataccttga
     4561 ctcagtcaat gctaaagcga ttagctttgc tcgctttgaa gtcggtgaag gtattgagaa
     4621 aaaagctaac gactttgaat cagaggttgc tgctacaatg gcagctgcgc ttaacaacta
     4681 gtctaatcat aagtcataag attgaggaca gcttttaaga gctatcttca atcttttttt
     4741 acgcctaaaa aaagagcttt tcgagcctat ccaacacaaa aagactaaga gaagcatgcc
     4801 ttcctccaca agctagacta tacgttctaa cgataggagg gccgtacaaa gcctcttagt
     4861 ctttttttaa tgagcaatga ttaccaaata atcacacgat cctctggagc acgccacatt
     4921 ggatcacctt ctttaatgtt aaattcttgg tggaattcat caaagtttgt caaggtcaca
     4981 ttagtacgcc attgaccagg tgcgtggacg tcaatacttg ccatcatttg catgaattcc
     5041 tcacgcgcct tcatacgcca gatggtggca aagttgataa agaaatctct ggcagaaaaa
     5101 tctggctctg actgagctgc ctctaaggca caggcaacac cacctaggtc agcaacattt
     5161 tcagacactg ttaatttacc attgacttta gcaccatagg agtcaaggcc atcaaattgc
     5221 tctacaattt tatcggtacg ctccttgaag gcggcataat cctcgtctgt ccaccaattc
     5281 tttaggctac catgctcatc aaaggaagca ccgttggtat caaaggcatg cgaaatttca
     5341 tgagcaataa cagcaccgat accaccataa ttagctgatg agctttgact caacgaataa
     5401 aacggcgcct gcagaatagc tgctgggaac acaatttggt tttgctgtgg gtcataataa
     5461 gcattaacca tgttggcagg catgtgccat tcactacgat ccacaggctt attccacttg
     5521 ctccatgaat gagcaattga aattttggct aaattctgag cattttcaac aagtgatagc
     5581 ttatcatcga tgaccttttt agcataggtt tctggtaatt tttccggata gccaatgtgt
     5641 ggggtgataa catttagctt tgtaatggct ttctcacgtg ttgctggtgc aagccaatcc
     5701 gcagtttcaa gacgagattt ataaacctca atcatcttag ctaccttgtg ttcaacatca
     5761 gccttagcct ctggtgaaaa tttttcacca gcataccaaa gcccaagagc ttgattaaat
     5821 ggtccttgtg ctaagtaata ggctgctttt ttcttgtcca tagcctgtgg agttcctgac
     5881 aaggcacgac tgtaaactcc tgatagcaca cgaatctcgt cagtcaaata agcatgataa
     5941 gcacctgctg ctgtaagcac tagccaggct tttagcagct cccaattctt ctcagaataa
     6001 tagtcagctg caaattctgt ccagaaccgc tcctctggca caacaacctt gtctggtact
     6061 tcacctaaaa tcacagtaaa tatattatct aaaggcaatt ctggcactag cttggtaaac
     6121 tcggcccagt cataagggtg gtaaagcttg gcatactctg aatattcctc acgagaaagg
     6181 acataatctg ccagctgttt atcaagcgtg ataaccttat ccagcaagtc cttaacctct
     6241 tcatgtgaaa agccaaattt aggcaatagc tcctcttgca tgccacgcca gatagcaagc
     6301 agctctttgc ctttgtcatt gtctttggca tagtaagtgg tatctggcag gataagacct
     6361 ggtgcctctg cccaaaggac atttaactga gcattcataa agtctggtgc tacactaaat
     6421 ggaaactgat ttggttttcc atttagctca taatcagcca ccttgctagc aaactcggca
     6481 aaagatccta aggccttgta ttcttcaatt aagtccaagg ctggcgctac gcccacctga
     6541 tcacgcttgt cataatctgc aaccaagcgg tgaaacttga caaagttttc taatatagcg
     6601 tcattgggaa catgctcacc agccaaccaa gcatctgttg tggtcagcat taagtcctca
     6661 atctcatctg ctaggtctga aaagccccct gtacgaggct tatcgtctgg gataacagct
     6721 gtttctgccc attgaccatt gacggcttga taaaaatctt cttgatatgt tgtcatgaat
     6781 tgctcctttt ttaaattaaa ccattatgtt aggactagct tttactcctc ataatgtaat
     6841 ctcttacatt ttaccaaaaa atcgttcaaa atactcgttt tatattaact ttctgttcaa
     6901 aaataagctc attcttcgta tcgcatggca tagatagtaa acgcttagct gctttggtcc
     6961 ttttatcagt aagattaatc ataaaaactg aacaatcact aagaaatcaa acgattcttc
     7021 tccagcttca tgaaaacagc cctcacaata tgccaaaaac tcagcagtaa tagcaaaagg
     7081 ccctatcagt cctgacaaaa gaattgcacc ccaaaggtga agataaaacc taaagcttaa
     7141 gaactttttc tatgacatta aaattagaag gtgaaatcaa gagttatcaa tcattatttc
     7201 acgcctacag agtgaaaggg actgaaagcg cataactaaa aggactgaac cctgtttcat
     7261 acaaagctca atcctaatct ataaggtcca gctttttggg tgtggtacac ctgataggct
     7321 tttttagcta atctgccgct aaaatcctca aaacctgctg ctcaatagct gctggcgtca
     7381 gctggtattc ctctaataga taatccatct gtccgacctg accgaaacgt tcgtccaccc
     7441 ccatacggta aactggagta ttactttcct gagccagtag ctcacagata gcactcccaa
     7501 gcccaccgat acgattatga ttttcaacgg ttagaacagg actgcctgta agtagaccct
     7561 ttagctcatc ggccagtggc tttaccctga aaacatcaat cacaccgata gagtagccct
     7621 gctctgccat tttatcggct acctctaagc accttttgac catgatccct gagcaagcca
     7681 gcacaaggtc ttttccttga cgcaataggc aatagccatt agaaaagtcc tcatgccctt
     7741 gataaatagc ctctggcttt ttacgaatgg ttcgaatgta ttttaggcca tcgagtgata
     7801 gggtttcctt taaaacagct ttaaattgaa cgtcatcact gacctcataa acaatagccc
     7861 ttggaatcag gcgcagcagt cccagatcct caaagggcat atgggtgccg ccattcattt
     7921 ccgcactaac tccggcatca gagccaataa ccgttgcgcc tagctgggca taggctaatg
     7981 aaagaaacag ctgatcaaac acacgacgtg aggcaaaggg accaaaggtg tgtaggtaag
     8041 gcttatagcc tttaatcgcc aggcctgctg ccagaccgac catttctgct tccataatgc
     8101 ctacattaat atagcgcttg ccaaacacct gatccaaatg gttggtggcc attgagcttg
     8161 ataaatctgc ctctaagacg actacctcag ggtgctcttg gttggctgca atgaggaaat
     8221 ctcggtaaac atgacgcatt tcttgacttg ctcgagtcat cttgtcacct ccaaactagc
     8281 tcgtagcttt ctgacagcgg cagcaagcat ctccttttcg gctgctgttg gtcttagatg
     8341 gtggttagct gccattgact ctagctggct aacaccctga cccttgacgg tatctaagac
     8401 gatacacttg ggcttatgac ttgatgacgc ctgcaaagcc ctgatggctt caaaaatagc
     8461 ctgaacatcc ctaccatcta cacgtaagct ttcaaagcca aatgccgtaa acttttcaac
     8521 aaaatcacct ggacgacaga ttgcctcggt tgttccatct aattgcttct tattgtcatc
     8581 aacaaagaca atgaaatgac ttagctgctg gtgtgccgca agctggatag cctcccagca
     8641 ttggccctcg tttaattccc catcaccaac gattgcatag gtataatgtg gtgactgctc
     8701 aagcgcttga gcataggcaa tgcccgttgc tacgctaatt ccctgaccaa gagagcctgt
     8761 cgtcatgtca ataccaggcg ttaacagacg atctgggtgc gagggcagac ttgttccatt
     8821 ggtattaaga gactgtaaaa aggccttatc aaaaaacccc tttaagtaga gagtgctata
     8881 gagggcagga cccgcatgtc cctttgataa caccagataa tctctatctg actggacaaa
     8941 gagctctggt gtcatgggca tgatttctcc ataaagcaca gccagcaatt ctacaataga
     9001 caagctaccg ccataatgac caaagccaag atgattaaga gtctccaagg tatttagacg
     9061 aatctctgct gcgaatcgct tcacatctgt tagaggctca tcactcaaaa ccatgcttat
     9121 tcctccttag ctactgattt tccaacaaca gaaagcccaa caagtccagc taatatcaca
     9181 aaaataccaa tcacaatagc tgtcacacca cctatgctgt taagtgttcc tagtaaaata
     9241 cctgataagc caaaatcggc atctgagaag gttgagccct caaagcccaa gccgcctaaa
     9301 acaggcatca agaaaatcgg aagatagcta ataagaacac cctgtaaaaa ggctcccaca
     9361 gttgcaccgc gcacacctcc agaagcattc ccaataacac cagctgtggc accacagaag
     9421 aaatgaggca caacgccagg taaaatcact gtcgttccac ttacgatcat cacagccatg
     9481 ctcacaaggc caccaacaaa gctagaaaca aagccaatca gcactgcatt gggggcataa
     9541 ggataggcaa tcgggcaatc caaggccggc ttagaatgtg gcactaattt ttcagaaatg
     9601 cccttgaagg ctggaacaat ttcacccaga atcaaacgaa caccagctaa aatcacaaag
     9661 acgcctgcag caaactgtcc tgccaactgc aaggcaaaga ccaagccatg tgtgccagag
     9721 gataattcct tactaatcca agtaggacca gcaaaaatag ctacaatcaa ataaatgatt
     9781 gccattgata aggtaatgct tactgtacta tcacgcaaaa aagcaaggct ctttggaaaa
     9841 tcaatgtcct ctgttgactt ggttttgtct ccaacaagac ctcctacaaa accgcttaac
     9901 caataaccaa gagagctaaa atgccccaaa gcgaccttat cgttaccagt cagctggatc
     9961 atataccgtt gcacaagagc cggtgaaaca ctcatgataa tccctaaggc cagcccacca
    10021 aacacaatca aggacactga cgtcaagcct gcaacagaca taatcacagc aatcatacag
    10081 gccatgtaaa gtgtgtgatg ccctgtcaag aagatatact taaatcgggt aaagcgagca
    10141 atcaaaatat taaagatcat tcctgtaaac ataatcagag ctgtcgctga cccataggtc
    10201 gtcaaagcaa ctgcaacaat agcctcatta tttggcacaa caccagacag atgaaaggca
    10261 tgctcaaaca tcgttccaaa agggttgagt gagccttgca cgatacctgc accacctgaa
    10321 accactaaaa acccaacaaa ggtcttaatg cctcccttaa caatgtcagg agcaggcttt
    10381 ttttgaagta agagaccaac aatagcaatc aaggcaacca aaatagctgg tgtgctaaca
    10441 atatcaagta aaaatgtcat cttatcctcc ttctaaacaa gccccttttc ctggcaaata
    10501 gcctttacca gactagtcaa ttcgtccata tcaatgatac tatttaaaat cctcacatct
    10561 cccagatgct ctgccgagtc tgccaaatca cgcccaacaa tccacacatc tgccgctgtg
    10621 ggatccgcgc caccaagatc ataatgctcc acctcaacac cggttactcc caagtccttt
    10681 aatacggatt cgatattcat ctgaaccata aagctagacc ctaagcctga accacaggct
    10741 gtaccaattc ttaatgccat tttatgcctc ctctgcaata atagttttaa tatcctcaaa
    10801 tgatttagac gcaagtaaag ccttgacctg ctcattgtct cttaaaatgg tcgtcagccg
    10861 agacagggcc tttagatgtg tttcattatc aatagcagca atacaaatta acaaacgaat
    10921 ctcctgctta ggatcatcta acaaataaat cgggtgctct aaaacaagca tcgacatacc
    10981 tacctgattc acaccatcct ctggcctcgc atgtgggata gcaatcccct tacctagatt
    11041 aataaaagta ccaaactcct caaccttagc aatcatagcc tccgggtagc tcgcttgaat
    11101 ctgcccactc tctaacaagg gctgagccgc caaataaata gcctctctcc accccaattg
    11161 ctctgaggtt gattgatagg ttttcttggt aattaagtct tgtaacactg gtcgaatatc
    11221 ctttcttttc acaccttgtc ttaaatattg ctgcaaagca aagcgcagct tttctttttg
    11281 atgaatgacc gcatatgagc tgataagatg gagcagctct tcaacctcta gccgatagcc
    11341 aatatctgga aaatcacgat taaccaagct gaccagctga aaagcctgct catcagtcat
    11401 tatcataggg actaaataaa agggcttatc agtctctaat cgtatcgttg aaaaaaccaa
    11461 atcatagccg ctcttatcta attgcccaag ctgatcaagc cttgaaagcc cccgaaaagc
    11521 aatatcagga aataaaagct ttaaatgctc cttgatcatt aaagaagaac taacaccatt
    11581 aggacagaca atcacagcct gataggcttg acgatgaaaa tctcttccct gctgctttaa
    11641 atagcctcca aaatgaagaa caaaataagc aatttcacta tctggtatag gactacccag
    11701 ctccttggct aaaggctcca gagactgctt taccaagtca aaaagctcag aataactatc
    11761 cttaatccgc aaggtataat cattatcact tggcaaacca tagcgcaaac ggtaataggc
    11821 tggaatcaaa tgccttttca aattctcctt gagctgatct gcctgactaa agcttagtaa
    11881 agcaaccccc tgcatttgat caacaatcgc aacggttagt gattcaaaga aatcatcacc
    11941 aacagtaccc tcaccctcaa agcagcccgc taacagcaat tgaaaatagg cctcatcagc
    12001 ttcaaatagc tgatacttaa gagacaattg ctgcattatt tctgccacca aaagggccgt
    12061 tagctgatcc agctgctcag aaaccactac ctgtctttgc ttgaccctat caacccgtct
    12121 ttggtaacga cataaaataa agatgacagc gtacaaacag acctgcagac gatcaaggat
    12181 cggagacatc tgaaaggtct gataaaaatg gctcacacgt ttttcaagcg cttcaaacga
    12241 cacctgatag tgccaagaag ccaaaatata gtccaaggcc cacaagccaa taggagattt
    12301 aagcaaagta gcaatcatta ctaaagccaa ccggtgctta ttaatctcat caccaactaa
    12361 gatatagccg cttgctctgg tatactttaa ttccaagtca acatctgcca gcttctgccg
    12421 caaggcctta atatctgtca aggctgtgtt cttgctgacc tttaaaaagt cctgataatg
    12481 actatttgaa acaaaatccc tgcggcaaaa ggtatacaga tagataagat tgatccgctc
    12541 tgcctgagaa agataaacct gctcagcatt aatcaacgta aacaaatgat ctgactcagc
    12601 cttaagctgc tgactgatcc gatagccaga ccttgttgca tctagctctg agagctcatg
    12661 ctgagccaaa aactcattca gctcatcaat acggtcctta atctctctaa tggtgaattt
    12721 tgtcttaaca ctcagctcgt aaagtgataa gtcttgataa gtcatcaacg tcatcaaaat
    12781 gacaactgct ttgctatcaa ccatttgatt tcctttctaa attcattcta tcgaaaacgg
    12841 ttacaataaa ctagtcccca ttgggcacaa tttcttatcc aacatcatca acagcccttg
    12901 ggctcaagat gccaatctaa acaggctacc agctcctcct aactatcaat aaagagcaaa
    12961 caagcccatc tctgccgcta agcaattgtc cccatgattt cctaagtcca agccaaagct
    13021 aaagctcttt ggagtaataa ccgtcaaaaa tgttccaaat aatcaaaaaa actgattgac
    13081 ctcatcagca tgtgataact ctagatataa gcctaaaaca agattacaga cttaatagtt
    13141 aactggtaat cttttattat accacgaaaa cggttaccaa aaaagacttg tgttttatta
    13201 ttttaataat ataatgaaac tataagatat cttattaaat gacaaataac taccatcttg
    13261 gttagaaagg agtaaagcta attaaccctt agtagatcac catcgttttc agaaaggaaa
    13321 ttcaaaatga aaaaagtaaa acaattgatc atcgcaatga tagcgtcctt attactcatt
    13381 gctaacactg taccttccat tgtatatgct agtgaagtga ctaaaattca acaggaagaa
    13441 aaagtaattg aagaaaaatt atcacaacct ctagaaattt caaaaagtga gttagataca
    13501 ttaatccaag agaaaaaagc tctttatcca aatttaacag aacaagaaat gcgtgaaatt
    13561 gcgtataaag ccatgagtcc atacactttt agagctagtg tatgggacgg gcaaggagta
    13621 accttagatg aattcgcttg ggcttttgat gttattgtag gcgggttaat tagtggatat
    13681 gcaaccatcg gaaagtacgt tgccaaacat ggagtagctg ccgctcgagc tgtacttagc
    13741 cgagctgcaa aagctgcagc tcaacgactt ggtgtactaa ccggatttat ttccggttta
    13801 cttagagctg cattctcagt aataaacatt tactataatg tcggatatgc cctagcacaa
    13861 tatgtcgatg ctcgagatta tcacccaaat aacggtcgta taaatgcgtg ggcttaagaa
    13921 ctatatttgt tattttatta ttgtaatgtc agtttataca gcaatagcat attgtttcaa
    13981 tcgcttatcc ttatcattta ctccaaaact agttttctat tcggccataa ccacctatac
    14041 tttttacata acaaaaaata aagactga
//
LOCUS       DARYLJ010000048        14028 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYLJ010000048 DARYLJ010000000
VERSION     DARYLJ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14028
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..165
                     /locus_tag="TU746_001585"
     CDS             <1..165
                     /locus_tag="TU746_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891904.1"
                     /translation="VTYDSLVGQTRRHFDDKVAQARGLATKFKTVKEQLEEGIERTIA
                     TDQKLGGDFS"
     gene            162..554
                     /locus_tag="TU746_001586"
     CDS             162..554
                     /locus_tag="TU746_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891905.1"
                     /translation="MTALEKIRAAIRQKEEELEELQEHYHQERLQMAAAHDELRGNYN
                     QLQELYASTYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            573..857
                     /locus_tag="TU746_001587"
     CDS             573..857
                     /locus_tag="TU746_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891906.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGCLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     gene            complement(1056..1304)
                     /locus_tag="TU746_001588"
     CDS             complement(1056..1304)
                     /locus_tag="TU746_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL0891907.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(1358..2278)
                     /locus_tag="TU746_001589"
     CDS             complement(1358..2278)
                     /locus_tag="TU746_001589"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL0891908.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            2512..3141
                     /locus_tag="TU746_001590"
     CDS             2512..3141
                     /locus_tag="TU746_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0891909.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            3240..4517
                     /locus_tag="TU746_001591"
     CDS             3240..4517
                     /locus_tag="TU746_001591"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL0891910.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            4531..5193
                     /gene="deoC"
                     /locus_tag="TU746_001592"
     CDS             4531..5193
                     /gene="deoC"
                     /locus_tag="TU746_001592"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL0891911.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            5180..5569
                     /locus_tag="TU746_001593"
     CDS             5180..5569
                     /locus_tag="TU746_001593"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL0891912.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            5660..6712
                     /locus_tag="TU746_001594"
     CDS             5660..6712
                     /locus_tag="TU746_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL0891913.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6839..8371
                     /locus_tag="TU746_001595"
     CDS             6839..8371
                     /locus_tag="TU746_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0891914.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            8364..9428
                     /locus_tag="TU746_001596"
     CDS             8364..9428
                     /locus_tag="TU746_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891915.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            9430..10386
                     /locus_tag="TU746_001597"
     CDS             9430..10386
                     /locus_tag="TU746_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0891916.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(10424..11680)
                     /locus_tag="TU746_001598"
     CDS             complement(10424..11680)
                     /locus_tag="TU746_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL0891917.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(12200..13915)
                     /locus_tag="TU746_001599"
     CDS             complement(12200..13915)
                     /locus_tag="TU746_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL0891918.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         4038 a         2515 c         3280 g         4195 t
ORIGIN      
        1 gtgacctatg acagccttgt cggtcagacc aggaggcact ttgatgacaa ggtcgctcag
       61 gccagaggac tggccactaa gttcaagacc gtaaaggagc agctagagga ggggatcgaa
      121 aggacaatcg ctactgacca aaagctagga ggcgactttt catgacagca ttagagaaga
      181 tcagagctgc tatccgtcaa aaggaagagg agctagagga gctgcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctgc
      301 aagagctcta tgcctctacc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gcctgataac agaccaatat accgttctaa cgaggctgat tgatgactat cagcaccgaa
      421 cagagcagtg ctatcacgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggctatag agaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga agatgattgc tatagagatg atcttaaccg
      601 gacaagagcc gatcaggact ttaaagaaag agctggatag gagattagtt cagtccatat
      661 gtgccccctt gaccttaggt tgccttcatg cccttcaaag gcgctatgac agtgaggtat
      721 ctcggattgc cacagacacc gcagatcata ttcagaccat tgtcaatcag ctagatagca
      781 gcattagagg gcaaggcagg acagcactag agcaagcgat caagacgcag aacaggggct
      841 atagcagcct gatgtgagac aggaaggact tactgtccta ccagctacag tcactacact
      901 gctagagctt gcggtgtgag cagcagtaag aggcaaaggc gttaccccag agggattgat
      961 ggatcaccat cactagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt ttcattggtt atgtattagc taagctttgc agcaagacgt
     1081 gctttatcgc ggcttgcttt atttttatga atcaaacctt ttgattgggc tttatcaatg
     1141 cttgaagaag cagcgcggaa aagctcttca gatgggttag cttcaaatgc cttgatagca
     1201 gtacgcatag ctgatttttg tgctgaattt ttttcgtttg ctttaacgtt aagctcagcg
     1261 cgtttaatag ctgatttaat atttgccaat gttttcacct ccaaattaat ctaactacac
     1321 cattatatag aaaatatagg tgtttggcaa gcacttatca ctttttgaga taaatttcat
     1381 caattttatg gtctgcagct ttatgaagaa tgagctcagc tcgattgcgt gtaggctcaa
     1441 taaacttttc cagattttct aggttaattg ttttccagac tttttttgca aaggcaatgg
     1501 cttcattttg tggcaatgag gtatatctag tgtaatagtt agccggatca tgcttagcca
     1561 gctctaaaag gcttaagaac cgttccaaat accattgctc aatatgatgg ctatctgcgt
     1621 caatataaat tgaaaaatca aaataatcac tcatatacaa tcgattattc tgttgatttt
     1681 gaaaaacatt aatcccttcg atgatgagga agtcaggatt ggtaaaggtt tgctgctgat
     1741 caggaacgat atcataaatc tcatgcgagt aaacaggggc tgatgcggtt tgtcctccct
     1801 tgacagtatc cagaaagttt aacaatagct ccatattata ggattctggg aagccctttc
     1861 gattcagcat attgtttttg atcagtgtgc tattagggta caaaaaacca tctgttgtga
     1921 ccaactcaac agtgctggtc ttgtgtgtgc gcgccaaaag aagctgcaat aacctgctag
     1981 ttgtggactt accgacggca actgagccag aaatcccaat aataaagggt ctttgctgaa
     2041 tatctttttt tagaaagagg cttttagaaa aagacaggtt ttcttgagcg attttataga
     2101 cttgaatgag atgaatcaag ggaaggtaaa cctcaacaac gtcgttgata tcaatattat
     2161 cattcaaact ggtgatgcta gtaagctcct cttgagtcaa taagggcttg cttttttgat
     2221 gtaattgctt ccaggatttt ctggaaattt tttcaaaagt aataaattcg tttgacatag
     2281 ttactcctac taattggcag tgcttacatt ataacatgtc aataaaaaaa ttgaaaaatg
     2341 tttcgtctga aattcttaaa aaaacactga aaaaccctat aaaaatcgaa caattttagc
     2401 ctaacaattg gctaatataa agttaatcgg tcaatgttcg gaatatatgg ttcgataaac
     2461 gaaaaaccaa gaaaaacaaa cgtcttgtaa accatttcaa agtgtgatag aatgaaaaag
     2521 catcgaaaaa agataggaaa acacatgaca aaaatgtatt atgatgaaaa tccagatagt
     2581 gctcatgata tccatcaatt gacggtcaat ttgttaggac agtcctttac ttttttgaca
     2641 gattctggtg ttttctcaaa aagaatggtt gattttggaa gtcaggtcct gctcaacaca
     2701 ttagattttc aagaaggtga tcgtctgctt gacttgggct gcggctatgg gccgctagga
     2761 cttagcttgg caaaggctca aggtgttgag gcgactctag tagatattaa tcatcgcgct
     2821 gttggcttag ctaagcagaa tgctgagagt aatcaggttg aggcgaccat ttttcaatca
     2881 aacctctatg acggtgtgac agggacattt gagcacatca ttagtaaccc acctattagg
     2941 gcagggaaaa aagtggttca tgagattatt gaaaagagta ttgatttttt aactaaaggc
     3001 ggtgatttga cagtcgttat ccaaaagaag cagggagcac caagtgctaa agacaaaatg
     3061 gaggccgttt ttgggaatgt gactattctc aaaagagaaa agggttacta cattttaaga
     3121 agtattaagg aaaggaattg agctcaagtg taaaaagtgg tattaaaaag catagcggta
     3181 ttttagtaag agttgccttc taatatcact attttctcag agcttttggt atcttgttga
     3241 tgagagcagt tgatttaatc caaaaaaagc gtgatggtaa agagctatct accgaagaga
     3301 tccagtggct gattaatggt tatgccaatg gtactgtgcc agattatcaa atgtcggctt
     3361 ttgcaatggc gatctatttc aagggaatgt ctacacgaga aactcgcgat ttgaccatga
     3421 gtatggttga gacaggtgag cagattgatt tgtcagctat agctggtatc aagacggaca
     3481 agcactcaac aggtggtgtt ggtgataagg tgacactcat cttagctcct ctagttgcta
     3541 gctttggcgt tcctgtagcg aaaatgagtg gacgcggctt aggccacacc ggtggaacgc
     3601 ttgataagct agaatctatc aagggctttc agattggtcg gacccaagag gaatttatca
     3661 agcaggtaca agagatcgga ctttcagtta ttggacaatc agataagctt gtgaaggcag
     3721 ataagctgct ttatgctctt cgtgatgtga cggcaaccgt tgatattgtt cctttgattg
     3781 caagctctgt tatgagtaag aaaattgctg ctggcgctga tagtattttg ctagatgtta
     3841 ccgttggtga cggtgccttt atgaagacta ttgaagatgc tgagaagctg tctagactga
     3901 tggttgacct tggtaaggag gttgggcgtc agacagtggc tgtcattaca gatatgagtc
     3961 agcctcttgg tcgtgctatc ggtaatcgct tagaggtgct agaggcaatt gatatcatga
     4021 aaggcaaggg acgcaaggat attactcact ttatttgtga gctagctcag attatgctgg
     4081 agcttgctgg tgctcaacac tctcttgagg atattcacca tcatttggtt ggcggagcag
     4141 ccttaaaaaa attagaagag atggttgttt atcaaggagg tgatcttgag gacctttatc
     4201 gtccatcaca ggcggctgtt caaacagagg tttttgcgtc agaagatggt tacatcacag
     4261 cattgcctgc tcttgagttt ggattgtttg caatgaggct gggtgctggt agagcagtca
     4321 aaacagatag tctggattat gaaacaggga ttgtctttga caagaaggtt ggtgacgctg
     4381 tcgctaaggg agagcgcatt gcagttgtct tttcacagga agccctagac gaaaaaatgc
     4441 ttacagaatt tgaaaaaaat gttaaaatag gggcggaaca cctagaggct aacgaaatta
     4501 tcaaaatcat ttcctaagga ggagtataac atgaatatta acaagtatat tgaccacaca
     4561 ctactaaaag ctgacagcgt tcaatcgcag cttgaccaat taattgagga ggctaaagcc
     4621 tatgactttg ctagcgtttg cgtcaaccct tgctgggtag cctatgctgc aaaggcttta
     4681 aagggaacag atgttaaggt ttgtacagtt gttggttttc ctttaggtgc aactacctca
     4741 gcaacaaagg cctttgaaac aaaggacgct attgaaaatg gtgctgatga gattgatatg
     4801 gttatcaata ttggtctgtt aaagcagggt gactaccaag ctgttgaaga tgatatgcgt
     4861 gcagtggtag aggctagcgg agacaaatta gtcaaggtga ttatcgaggc ttgcctcttg
     4921 actgatgatg aaaaggttaa ggcttgtcag ttggcggtaa atgcaggtgt tgactttgtg
     4981 aagacctcta ctggtttttc aactggcggt gcaaccgttt ctgatgtcaa gctaatgcgt
     5041 caaacagttg gtccagacat tggcgtaaag gcagctggtg gtgctcgttc tctagaggac
     5101 gctttagctt ttgtcgaagc aggagctaca cgtattggaa cttctgcagg ggtaactatt
     5161 atgaaaggtg aagttgccaa tggaggctac tgatttagtt tcgttagcca ttgaagctag
     5221 taaaagggct tatgtgcctt actcacattt cccgatcgga gctgctttaa agacaaagga
     5281 cggaacaatc tatactggca ataatatcga gaatgccagc tttggcttga ccaattgtgg
     5341 ggagcgaaca gctattttta aggctgtttc tgagggacat cagcagcttt tagaaattgc
     5401 catttatgga gagactgatg agccaatctc tccttgtgga gcctgtcgtc aggtcatggc
     5461 agaatttttt gaagccactg ctccagtaac gctaattgct aaggacggtc gtaccatgcg
     5521 cacaactgtt ggcgagttac ttccttattc gtttacagat ttatcgtaat ctggcttaat
     5581 tttgttatct agccattagg ctttatattt actttcggca attggtttgc tagaaatatt
     5641 tttaggaggg ttcatattca tgaacaagaa atttattggt gttggtttag cttctgtagc
     5701 tttattaggt ttagttggtt gtggtaatcg taacgcttca aagggatctg gtgatgctaa
     5761 aacagatttg aaggtagcag tggttactga cactggtggt gttgatgata agtcatttaa
     5821 ccaatcagct tgggaaggct tgcaggcttg gggtaaggac aatggactaa caaagggttc
     5881 aggctttgat tacttccaat ctacaaacga gtctgaatat gcaactaaca ttgatacagc
     5941 agtttctagt ggttatgagg ttgtttatgg tatcggattt gccttgaagg atgcaatcag
     6001 taaggctgct gatgacaaca acaaagtaca atttgttatc attgatgatg ttatcgaagg
     6061 caaagacaat gttgctagcg taacatttgc tgataacgaa gctgcttacc ttgcaggtat
     6121 tgcggcagct atgactacaa aaacaaaaac agttggtttt gtaggtggta tggaaggaac
     6181 agttgttaca cgctttgaaa aaggctttga ggcaggcgtt aagtctgttg atgactcaat
     6241 caagatcaag gtggactacg ctggatcatt tggagatgcc gctaagggta agacaattgc
     6301 agcagcgcaa tacgcagcag gtgctgatgt tatctatcag gtagctggtg gaacaggtgc
     6361 gggtgtcttc aacgaagcaa gaacaattaa cgaaaaacgt gacgaagctg ataaggtttg
     6421 ggtaattggt gttgaccgcg accaaaacga agaaggtaaa tatacatcta aggatggcaa
     6481 atcatctaac tttgtacttg catctactat aaaaggtgtt ggtaaggctg ttcaattgat
     6541 caataagcag gcagcagata agaaattccc tgcaggtaaa acaactgttt atggtctgaa
     6601 ggacggtggt gttgagattg ccacaacaaa tctttctaaa gacgttatca aagccatcga
     6661 agaagcgaaa gaaaaaatta aatctggtga cgtaaaagtt cctgaaaagt agttactgga
     6721 aaagagcgac cttcgtcggt cgcccttttt agagtggaac accttttgct tcagtaaagg
     6781 ttgtgacaaa tggctggctt tactgaaaca aaagattaaa ttgaaaggaa ataatcctat
     6841 ggcacagcat gtcattgaaa tgaaagagat tacaaaaaaa tttggtgatt ttgttgcgaa
     6901 tgaccatatt aatttgaatg tcagaaaagg cgaaattcat gcattgttag gagagaatgg
     6961 tgcaggtaaa tcaacgttaa tgaatatgtt agctgggctt ttagagccaa ctagtggaaa
     7021 cattgtcatt aacggtcagc ctgttgttat tgactctcct tccaaatctg ctagattggg
     7081 tattggaatg gtacaccagc actttatgct agtagaagct tttacagttg ctgagaatat
     7141 cattttagga aatgaagttg tcaaaaacgg ttgtcttgat ttaaaaaagg ccagcaagga
     7201 cattaaagag ctttctgaga aatatggttt agctgttgat cctactgcca agattgctga
     7261 tatttctgta ggggcacagc agcgtgttga aatcttaaag accttatatc gtggtgcaga
     7321 tattcttatt tttgatgagc caacagctgt tttaacgcct gctgaaatac aagagctcat
     7381 ggaaatcatg cgtaaccttg ttaaggaagg caaatccatt attttgatta ctcataagct
     7441 ggacgaaatt agagcagttg ctgatagagt cactgttatt cgacgtggga aaagtattca
     7501 aacagtagat gtagcaggtg caacctctca ggacttggct gaaatgatgg ttgggcgttc
     7561 agtttccttt acaacagcta aaaaggcagc agagccaaaa ggggtggtgc tgtcgatcaa
     7621 gaatttagag gtcgatgaaa atcgtggaat cccagcagta aaggggcttt ctcttgacgt
     7681 tagagctggt gaaattgtgg ggattgcagg gattgatggt aatggtcagt cagggctgat
     7741 tcaggccatt acaggcttga gaaagactag atctggtagc attacaatca aaggtcagga
     7801 ggttgttcat ttaagctccc gtaaaatcac agagctatca gtggggcatg tgcctgagga
     7861 ccgtcataga gatggcttag tgctggacct ttccttggct gaaaatactg cccttcagac
     7921 ctattataaa gagccactaa gtaagaacgg tattttaaat tacaatacaa tcaatgatta
     7981 tgctcgtaga ctgatgaagg aatttgacgt tcgtggtgcc aatgaattgg ttccagctcg
     8041 tggattttct ggcggtaacc aacaaaaggc tatcattgca cgtgaggttg accgtaaccc
     8101 tgatttattg attgtcagtc agccaactcg cggcttggac gttggtgcta ttgagtacat
     8161 tcataagcgt ttgattgaag agcgtgacaa aggcaaggcc atcctcgttg ttagctttga
     8221 gcttgacgaa atcttgaatt tatctgaccg tattgcagtt attcatgacg gtaaaattca
     8281 aggcattgtg ttgcctcaag ataccaataa gcaagaattg ggaattttga tggctggtgg
     8341 ttccattgat aaggaggaga gtcatgtcta aaaatgcaca aaagattgct gtgccaatga
     8401 tttctatctt gttaggattc ttacttggcg ctattgtcat gtttatcttt ggctatgatc
     8461 caatttgggg ctatgagggc ctatttcagg tagcctttgg tagtatcaaa aatattggtg
     8521 aaatcttcag agcgatggga ccactaatcc tgattgcact tggttttacc gttgctagcc
     8581 gtgccggctt ctttaatgtc gggctgtcag gtcaagcttt ggctggttgg attgctgcgg
     8641 gctggtttgc tcttgtcaat cctaatatgc ctcgtccgct tttaattctg atgactgtct
     8701 tgattggtat ggttgccggc ggaattgctg gcgctattcc aggtattttg cgagcttatc
     8761 ttggtacaag tgaagttatt gttaccatta tgatgaatta tattattctg tatgtcggta
     8821 acgctatcat tcaaagaggc taccctgaaa gtgttaagca aagtattgat tcaaccatac
     8881 aggtcagtga taatgccagc tatcaaagtc aatggctgtc agatttaacc aataattctc
     8941 gtattaatat cggtatcttt tttgcgctta ttgcaattgc agttatttgg ttcttactaa
     9001 acaaaacaac cctcggattt gaaattcgtt cagtaggtct taatccacat gcttcagaat
     9061 atgcaggtat gtccttaaag cgtacgatta tcctatcaat gatcatttca ggtgctttag
     9121 caggcttggg aggagttgtt gaaggcttgg gaacctttga gaatgttttt gtacagggaa
     9181 gctctctagc aattggtttt gacggtatgg ctgttagctt gcttgctgcc aattcaccga
     9241 ttggtatctt cttctcatca ttcctatttg gggtgttgag cataggtgct cctggtatga
     9301 atatcgcagg aattccacca gaattggtaa aagtagtgac tgcctcaatt atcttctttg
     9361 taggtgctca ctaccttatc gaacgctata ttatcaggcc taaaaaacta gtaaagggag
     9421 gtaaataaga tgagtttagt tactattttt gctttattgg tttcatcaat gcttatctat
     9481 gctacacctc ttatttttac aagtattggt ggtaccttct cagaacgagc tggtgttgtc
     9541 aatgtcggcc ttgaaggcat tatggtcatg ggggggggtt caggcattgt ctttaatctt
     9601 gaatttgctc atatctttgg taaagctact ccctggcttg cagttttggt gggaggagtt
     9661 gttggattga tcttttcatt gatccatgcg cttgcaacga ttaactttag ggcagatcac
     9721 attgtcagtg gtacagtgct aaatctgctg gcaccatcgc ttgccatttt cttagttaag
     9781 gtgatgtacg gtaaggggca aactgataat atccagcaat cattcggtaa gtttgatttt
     9841 ccgattctct caaaaattcc agttcttgga gatatattct ttagaaatac tagcttagtt
     9901 gggtatttag ctgttgcctt ttctttccta gcttggtttg tgctttacaa aacaagattt
     9961 gggttgcgtt tgcgctctgt aggtgaacac cctcaagcag ctgatacact tggtattaac
    10021 gtttacctca tgaaatatta tggggttatg atctctggtt ttcttggggg tattggtgga
    10081 gctgtctatg cacaatccat ctctgttaac ttcgcagtga caaccatttt aggacctgga
    10141 tttattgccc ttgccgctat gatttttggt aagtggaatc cggtaggtgc tatgctatct
    10201 agcttgttct ttggattatc acaaagctta gcagttattg gggcacaatt accagtattg
    10261 gaaaaaatcc caacggttta ccttcaaatt gcgccatacc tattgaccat catcattttg
    10321 gctgctttct ttggacaagc agtggctcca aaggcagacg gtgttaatta catcaaatca
    10381 aaataaaaaa agctcaatgt caactgtagt gggtgactga tagctaagca cgagagaaga
    10441 cgaatgtcgt cttctctttt gtgatattca aagcgaggta gatacgtttt ttaaagttgt
    10501 caaagttccg aaatccgaaa gcattgcgct tgatatcttt gataagtttg ttagtggctt
    10561 ctaacttagc gttagaataa ggcagttgaa tggcattggt gatgtaatct tggtagcgac
    10621 taaaggtatt tagagctgtt ttaaaagtct gattaagatg tggtagtgtg tcatgaatta
    10681 aaccaaagaa atgcttggca ttcttttctt gcaggtgaaa aaggagcagc tggtacaggt
    10741 cataataaga gtttaactca ggcactagtg agaagatctt attgagacat tctctaggag
    10801 ttaaggtttg tctgaaggtg cgggaataga aaggcttaag agaccgtttt ctgctatcct
    10861 tttgaataag cttccagtag tacttaagag ctctatattt aagagacttc ttgtcaaatg
    10921 gtttcatgat gtcactacgt atttgcttga gagctctatt gatgtgctgg acaatgtgaa
    10981 aacgatcgag aacgatttta gccttaggaa atagaatttt aatgagagga atataacttc
    11041 cagacatatc gacagtgacg actttcacct tgtttctagc ctctttagag tacttaaaga
    11101 aatgatttcg gatggttgtt tgacgtctat tatcaagaat ggtaatgatt ttcttagtgt
    11161 taaaatcctg agcaatgaag gctaatttac ctttctgata agagaactca tcccaagaga
    11221 gaacttctgg caaattggcg taatcctctc ggaaatgata ctgcttaagc ttgcgataga
    11281 cggtagaagt ggagatagcg agcttagaag cgatatgggt gagagccttt ctgttgagta
    11341 aaagctgagc gattttctgt ctcactatct cagaaatttg gcaatttttc ttaaccaggg
    11401 tagtttcaga tacagtgact tttcgacagg atttgcattg aaaccttctt tttttcaaac
    11461 gaatgagact aggaaagcct ccaatttcga taaagggaat tttagagggc ttctggaagt
    11521 cgtatttgat ttgttttccc gcacacagtt tacatttagg agggttatag tctagtgtag
    11581 cgatgacttc aatatgagta tcatgctgga tagctttagt caaggtgata tgtttgtctt
    11641 tgattccaat gagttgtgtg gtattattga ggtgttccat aagatacctt ctaaatgata
    11701 gtttagtcgc ttttcatgat aagtcttatg ggactttttt gatactcaaa aagccctata
    11761 atctccacag tagccttacc cactacagaa attatagagc catcttagaa cactggactt
    11821 gttcgctttt taatgaatta aatttagtag atcctttaaa ggcatgctat caagcttttt
    11881 atccttgact tttgtttagc aagtgaagtg ttcacaaaag ctagctaaaa cactgagctg
    11941 acaatgtaga gaatggctcg ttttgacaag gttagagtgc tttttgctgt atggttttta
    12001 atccacgcac ctgaaaaaga aaggacagga cctgtgcgag cttacttgtg gttagtaggt
    12061 ttcaattcat gctcccaaaa aggaagcaac gcaactctga gaaaggtctt agaccacttt
    12121 cccagtttgc ctcacagcta atggtgtaaa acaaatagac caccctgtaa caggtggtca
    12181 tggttagata tcagctcatt taagagacaa aggcgttgat ttcagattca atattggcaa
    12241 ttttttcttc ggcaagcgca agggtgtcac caacagttgc gatataaaat ttaatttttg
    12301 gctctgttcc tgatggtctt acagcaaacc atgaatcatc agctagggta tattttaaga
    12361 cattgcttgg aggagtggtt agctgggttt gaccagcttt atgagttgcc gtctgactga
    12421 ggaaatcctc tgttaacaca atatcagtgt gattaaactg cgcaggggca tgcttgcgga
    12481 atttatccat aatctgtttg atttcagctg cgccatcaac accagacagt gtaacagaaa
    12541 tggttttttc tgcaaagtag ccgtattctt tgtaaatgtc atcaatacca tcagcaaggg
    12601 ttagtccacg agagcggtag taggcagcaa tctcagccac caatagcacc gcttgaatag
    12661 cgtccttatc acgtacaaat ggtttaatga gataaccaaa gctctcctca aagccaaaca
    12721 tataggtgta attgtgcttt tcttcaaatt cttgaatttt ttcagcaatg aacttgaagc
    12781 ctgttaagac attaaacatg gttgccccgt agctctctgc aattttagtc actaattcag
    12841 tagagacaat ggatttggca agagcggcat tgttaggtag ggttccagcc tgctgatgtg
    12901 cttctaaaat atacttagca attaaagcac caatttggtt gcctgatagg ttgcgatagc
    12961 tgccatctgc ctgccgaatt tcaaccccaa gacggtcagc atctggatca gtagcaacaa
    13021 gaacatcagc atcaacctga cgtccaagct cctcagcaag agtaaatgcc tcttgacttt
    13081 caggattagg agatttgacg gtagaaaaat ctggatctgg cttagcctgc acctcaacca
    13141 cctgaacgga cttaaagcct gcttgtgcca aggcacgacg tgctagcatt tcacctgttc
    13201 catgaagagg tgtatagaca attttcatgt cacgaccata gtcattgatg aggtcttggt
    13261 tgatattgac ctttttgacc tcttctaaat aagcaaggtc aacagcttca ccaataacct
    13321 cgatgagccc attagctttg gctttctcta aatcagcaag cctaatggca aaggggttat
    13381 caatcgcacg aatgtaatct gttagagcgt cggcgtcagc tggaggcatt tgaccgccgt
    13441 cagacccata aaccttatag ccgttgaatg gtgcagggtt gtgactggca gtaaccatga
    13501 taccggcaaa agcacccaaa tgtcgcacag caaaggaaag ctcaggtgtt ggccgaaggc
    13561 tttcaaaaac gtatgattta atgccatgag ctgctagtac ctgtgcagat tcaaaggcaa
    13621 attctggaga aaaatgacga gaatcatagg cgatagcgac accggccttc ttagcagctt
    13681 ctccctttga ctcaactaat gctgccaagc cctcagttgc ttggcgaaca acaaaaatat
    13741 tgatacgatt cgttccagcg ccaatatagc cacgcatacc agctgttcca aattcaagat
    13801 tggtgtagaa ggcatcttcc tttgtttttt cgtccatgct aagtaattca tctcttaaat
    13861 aggctggtag atctggaata tcaagccatt tttgatagtt ttctgtgtaa gtcatagtat
    13921 tctcctttat atttttaacc gctttcatta tatcatgttg aaaaggaaaa atcacttatt
    13981 ttctgtaata gcttccaatc attttttcac ataaggatca atttcctt
//
LOCUS       DARYLJ010000049        13246 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYLJ010000049 DARYLJ010000000
VERSION     DARYLJ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13246
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            304..1848
                     /locus_tag="TU746_001600"
     CDS             304..1848
                     /locus_tag="TU746_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0891919.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            1932..2960
                     /locus_tag="TU746_001601"
     CDS             1932..2960
                     /locus_tag="TU746_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL0891920.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            2981..4771
                     /gene="uidA"
                     /locus_tag="TU746_001602"
     CDS             2981..4771
                     /gene="uidA"
                     /locus_tag="TU746_001602"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL0891921.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            4813..5484
                     /locus_tag="TU746_001603"
     CDS             4813..5484
                     /locus_tag="TU746_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL0891922.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            5667..6284
                     /gene="eda"
                     /locus_tag="TU746_001604"
     CDS             5667..6284
                     /gene="eda"
                     /locus_tag="TU746_001604"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL0891923.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            6312..7709
                     /gene="uxaC"
                     /locus_tag="TU746_001605"
     CDS             6312..7709
                     /gene="uxaC"
                     /locus_tag="TU746_001605"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL0891924.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            7971..9065
                     /locus_tag="TU746_001606"
     CDS             7971..9065
                     /locus_tag="TU746_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL0891925.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            9081..9920
                     /locus_tag="TU746_001607"
     CDS             9081..9920
                     /locus_tag="TU746_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL0891926.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            10184..10987
                     /locus_tag="TU746_001608"
     CDS             10184..10987
                     /locus_tag="TU746_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0891927.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            11102..12892
                     /locus_tag="TU746_001609"
     CDS             11102..12892
                     /locus_tag="TU746_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL0891928.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
BASE COUNT         3625 a         2449 c         3242 g         3930 t
ORIGIN      
        1 gttggtgggg tgacgatact gacctcaaag gggttggata agtattggta aaaggcttga
       61 gctctgtctt gtgcagggct cagttttttt gatgtcaatg agtaattgtc tgatgattat
      121 ttttaaagac accagaaatt atcagatgaa tttaatgatt aaaatcctaa ataagcttta
      181 ttttttaaaa ttaggcgaaa aaagtttaaa ttgtgttgac aaatcatcag atgaatagta
      241 agataagcat gtagaaataa aacgcttaca caataagcga atgataaaag ggggatttct
      301 ctgatggaga aaacaattga ccaaagggtt gaagaggtta cctataaccg cgctaaggtt
      361 tggcagcttg ttttatttgc tttaaacaat gcttcaacca atatctacct attcacattt
      421 atgtttgtga cctacttttc aacaggtgtt ctaggcttgg cagctatttt tgtcagccag
      481 atcatgggtt atattcgtat ttttgatggc tttattgatc ctgcgattgg tatcttgatt
      541 gataaaacag aaactaagtt tggtaagtat cgtccgatcc taatcatcgg aaatattatc
      601 acagccctat cacttattct gctgcttggt ctaagtggag ttagtgagaa cattcgtttt
      661 ccacttttta ttctggtttt gattatccat aagatcggct actctatgca gcaaaccatc
      721 actaaggctg gtcagacagc ccttactaat gatccgaagc agcgtccaat ctttaacatt
      781 gttgatgcca ttatgacaac cttgctgatg actggtggac agtttgttgt gtcaagcttc
      841 ttggttccaa aatttggtaa cttcacacca gccttcttcc acgtgttgat ttatggcacg
      901 attgttatct cagctatttt gggtctattg gcagtgcttg gtatttggag caaggacaga
      961 aaggaattct ttggtcttgg tgaaaatacg caaaagacag ctctgaagga ctatttgaag
     1021 gttatcaagg gcaaccagcc gctacaggtc ctatcaattg ccgcagcctt ggttaagttt
     1081 gctgttcaat tctttggtga ttcggttgtc atggttatct tgtttggtgt tttatttggt
     1141 aactatgctt tgtctggtca attctcattg ctgtttattg ttccggggat tttgattaat
     1201 attgcttttt caggtattgc tcgtaagaga ggtttgcgtt tctcatatat cagagctctt
     1261 cagattggct tggttggctt gttagccttt ggtattgtgc tctttatggg taataaaggg
     1321 gatctcagcc taagtcatat taacctttac actattttgt ttactgtgac actgattatt
     1381 gctcgctatg cctcacaagc gcctgctagc ttggtgctaa caatgggagc tgatatttca
     1441 gactacgaaa catcagaatc aggccgttat gtctcaggaa tgattggtac aatcttctcc
     1501 ttgactgact cgattgcatc atcatttgcg ccaatggtta ttggtgcagt gctggctggt
     1561 attggttttt caaagactta cccaacgatt gagacaccgc ttaccccaag tctaaagatg
     1621 gccttgattg cgctgcatgt cggtattcca tttgtagcct tactagtggc tttgattttg
     1681 atgtcattct acaagcttga caaagaggaa atggtgcgta ttcaagagaa gattcaagtg
     1741 atgaaagcaa gctctgataa ggaacgcgtg caggctatcg ctaaaaatgt accactgtca
     1801 gacatggact atgttgatgt gacaaaatat cctgttgata aggattaggt gctgggtcag
     1861 ctatttcttt gaggagtggc tgactttttt ataaaataat agagtagctt gatagtataa
     1921 ggaggaatgt tgtgaaaaaa gttgtatcct tgggtgaaat cctcttgcga ttgtcacccc
     1981 ctcaatacca gacgttaaag caggcaacaa gcctagattg tcaatttgga ggttctgagc
     2041 ttaatgtcat ctcaagcctt gctcagctag ggcatcaggt ctctcttatt tcagctattc
     2101 cagacaatga tctgggacaa atgacaaaaa cctttctctt ttcgcgtcaa attaatcagg
     2161 agcatattat cgaaaagggt cagcgtttag ggctttatta ttatcaaaag ggcttttctt
     2221 tgcgagcaag tcgggttacc tatgaccgct gtcattcagc cttttgggag tcaaagcgtg
     2281 ctgactatga tttggagcat gtttttgatg aggctgattg gtttcatgtg tctgggataa
     2341 cgcctgctct aacgagtgat ctttatgagc tgacctatta tttgatgaca aaggctaggg
     2401 cagagggatt gactatttcc tttgatttga attttagggc tagtctatgg tcctcctttc
     2461 aggaggctag agatctcttg tcgcctcttg ttcagctggc tgatgtttgt attggcattg
     2521 agccgctgac gcttaaggga agcggcgcgc ttgatttaaa ggatcaatta ggcttgaata
     2581 gaccctatga tgatgaagcc ttgttgaagg aggtgctggc taggttagct gatacctatg
     2641 gggtaaaatg ctttgccttt acccagagag agatggacta taccaatgaa tacctgttaa
     2701 aggcctacct gtatcaaaat ggcagccttt ataaaaccca aaaatctggt attcaggttc
     2761 tggaccgagt agggacgggc gatgctttta cggcagggct gattcatggc ttattaagtt
     2821 ataaagacga gcaggctact ttagatgttg caatggctag ctttaagttt aagcatacca
     2881 ttgagggtga tagtaatatc atgacacaag atgacattga tcatttactg gccaaggaat
     2941 cgcatgagat tcaacgataa tgtgataaag gagaaatcgt atgttatacc caatactgac
     3001 aaaaacaaga aagatttatg atttaggggg gctctggcaa tttaagctag gagaccataa
     3061 cccgcaggag ctcctagcct ctgatgagct gatggttgtg ccgacctcct ttaatgatgt
     3121 ggttgtggat aaggacaagc gcaattacat cggtgatttt tggtacgagc gctttgttga
     3181 tgtgccagat cttgctgctg atgaggagct ggtacttcgc tttggctctg tcacgcacaa
     3241 tgcaacagtc tatgttaatg ggcaagcttt agggcaacac aagggaggct tcactccatt
     3301 tgaggtgttg gtgcctgaga cccattatca ggataatcaa attaaggtat ctgtttgtgc
     3361 caataatatt ttagattata ccagccttcc agtgggcaat tatagtgaag aaactcaaga
     3421 ggatggcagt atcaaaaaaa ttgtcaagga gaattttgac ttcttcaact atgctggtat
     3481 tcaccgtcca gtgaagctta tggtgcggcc aaaatgccat atctcagata tcacgatcac
     3541 gagtgacttg tctgaggata tgacatcagc cttagtcgag gtatctgttg aaacctcagc
     3601 agctgttgat gaggttaagg tgacgatctt tgatgaagag cacaagctcg ttgcgcaggc
     3661 tattgatggc aaggcaagac ttgataaggt tcgtttatgg gaagttttag atgcttatct
     3721 atacactgcc cacgttgaga tcatcgtaga tggcaatgtt gtagatagtt atgatgagcc
     3781 atttggtatc agaagtattg cagttgaaaa aggacaattt ttactaaatg gcaagcctgt
     3841 ttatttcaag ggctttggta agcatgagga tacctttatc aacggtcgtg gattgaatga
     3901 agcagctaat ttaatggata tgaatctgct caaggagctt ggtgccaatt catttcgtac
     3961 ctcacactac ccttactctg aggagatgat gcgtctggca gatcgtatgg gaatcttggt
     4021 tattgatgag gttccggcag tagggctctt ccaaaacttt acagcctcct tggatctttc
     4081 gccaaaggac aatggcactt ggtctgtcat gaaaactaag gaagcgcatg agcaagcaat
     4141 tcgtgagctc gtcaagcgtg acaaaaatca cccttctgtt gtcatgtggg tcgtggccaa
     4201 tgagcctgcc agccatgaag agggagcaca cgaatacttt gagccgctga ttgctcttta
     4261 taaggcacta gatccgcagc agcgtccagt aacattggtt aatctgctat tagcaacacc
     4321 tgatcgagat aaggtgatgg atctggttga tgtgatctcc ttaaaccgtt attatgcttg
     4381 gtatgttgat catggagact tgatcaaagg agaggttggg ctgcgtcagg agctattaga
     4441 atggcagaag aagtttccta acaagcctat cctgatgaca gagtacggtg cagatacgct
     4501 tcctggtctt cattcgatgt gggatattcc atatacagag gaatttcagt gccgcttcta
     4561 tgagatgagt caccgcgttt ttgatgagat tcctaatcta gttggagagc aggtatggaa
     4621 ttttgctgat tttgaaacta atctgatgat cttccgtatt caaggcaatc ataaggggct
     4681 tttttctaga aatcgccagc ctaagcatgt tgttggtttg tttaaagagc gctggaatac
     4741 cattccccac tacaattata aaaagaaata gtgtacaata gtagctagca ataagtagga
     4801 agaagggatt gtatggctag gcctttagtc gaaaaaacag cagagcgctt gttaaagcta
     4861 attttagaac gtgggtatga ggttggagca aagctcccca atgaatatga gttagcacag
     4921 gacttagagg ttggaagaag cactattaga gaagctgtta gaagcttagc aactagaaat
     4981 gttttagagg ttagacaagg atcaggtact tatattagct cgaaaaaagg tgtttctgag
     5041 gatcctttag gcttttcctt agtcaaggac acagccaagc tgaccgctga tttgtttgaa
     5101 ttgcggctat tgcttgagcc taggattgcc gctttgacag cacagcatgc aacgccaaag
     5161 gaggttgaag ccttagagaa gcttgttgtt gatattgaag aggccgtagc tgctggtgat
     5221 cctaagcatt tgcagctgga tgtgaatttc cattccttga tggcaaaata cagtggcaat
     5281 attgctatgg atagcttgct accggtgatc aatcagtcga ttcatctgat caatgccaat
     5341 tacacaaatc gtcagatgaa agaagattct ctacaagccc acagagatat tctgaatgcg
     5401 attaaagcgg gagatccgat cgcggcacat gacgctatgc tcctgcacat catgacagtt
     5461 aagcgaacgg cttttctatc ataagcttaa gcttgcttgc cggaaacagt ctattgagtt
     5521 ttgagtgatt tgcttcttgg ctcgaataag agggcttggt tttagagata ctagaaccaa
     5581 gtcctttttt tgctttttcc ttgacaaatc atctgatgat ttatataata aaactaagac
     5641 aacggtttca tgaaaaggag gagcctatgc taaaccgatt aaaagagaat tatttttttg
     5701 ctattattcg tggaaaaaca gtagaagacg ctattgccat tgctaagcat gctattttag
     5761 gcggtattcg taatatcgag attacctatt ctactccaaa tgcttcagag gttattagaa
     5821 tattgtcagc tgagtttgag catgatgatg ctgtgattat tggagctggg acagtgatga
     5881 cgcctgatct ggcaagagaa gctattgcag caggtgctag ctttttagtt agtcctcatt
     5941 tttctagaga aatagcagag gttgccaatc aggcatcaaa tctttatttc ccaggctgtg
     6001 caacagctac tgaaattgtc acagcaatga atgcctcttg tccgattatt aaggtctttc
     6061 ctggaggtgt tgtaggacca ggctttatta aggatattca tggtcctatt cctgaggttg
     6121 atttgatgcc atcaggtggt gtgtcgattg acaatgtcaa ggagtggaaa aatgcaggtg
     6181 ctgttgctgt tgggattggt tcagccttag ctagccgagt tgaggctgag ggctatgata
     6241 gtgtaacccg tattgcagcg tcatttgtat cagcccttga ttaagggaat tggtcataag
     6301 aggaggacga gatggctttt aatgacgaca attttatgct aaaaaatgag gcagcaaagc
     6361 gcctctatca acaaatcaag gatcagccta tttttgatta ccattgtcac ttagatccaa
     6421 aggaaatttt tgaggacaag gtttatgaca atattgttga cctttggctt ggtggtgatc
     6481 attacaagtg gcgcttgatg cgcgctaatg gcatttcgga agaagaaatc acaggctcag
     6541 cctctaagct ggataaattc aaggcctttg cccgtacact tcagcgctcc tatggcaatc
     6601 ctgtttacca ctggtcagtg atggagttga aaaatgtctt tggtgtctgt gagctactga
     6661 ctgaggataa tgcagaggaa atctatcatc gtatcaatgc ttacttggtt gagcaccaga
     6721 ttagtcctag aaagttgatt gcagatagcc gagtgcggtt tattggtacg acagatcacc
     6781 cgcttgatga cctagcttgg cataagaggt tagctgctga tgataccttt gagacggttg
     6841 tcgcgccaac ctttagacca gatgaggctt ttattgagca tcagcgcttt gcagattttg
     6901 tggctcgtct tgctcaagct accggaagaa ctattacaga ttttaagagc tttatagcgg
     6961 ctatggaaga gcgtattgcc tattttgcag aaaatggttg taaggccagt gacatcagct
     7021 ttacagagat tgtctttgaa gcagcagagc cagagcaatt agaccgtctc atgacaaggg
     7081 ttttagaggg ctatcagccg cagccgttag aggtcaagca atggcagaca gcggtgtttg
     7141 cagagctttg caggctttat aagcactatg gctttgttac tcaggtgcat tttggtgctc
     7201 ttcgcaataa tcattcagct atattcaaca agctgggggc agatgtgggt gttgactcac
     7261 tgggagacca aacaggacta gcaatcaata tgaatcgcct gctggatcat ctggtgcaaa
     7321 gagacagcct gccaaagatg atttggtata acctaaatcc gagctataat atcgcggttg
     7381 ctaatacact agctaatttc caagccaatg aaaacggtat tgcgggctat ctgcaattcg
     7441 gtgcaggctg gtggtttgct gataccaagc ttggtatgat tagccagatg aatgccttgg
     7501 ctgagcaagg tttgttagct aattttgtcg gcatgctaac ggattcacgt tcatttttat
     7561 cctatcagcg tcatgattat ttcagacgta ttttgtcgac ctaccttggt gagtggattg
     7621 aagaaggtga ggtaccagag gattatcagg cacttggtaa aatggctcag gacattgcct
     7681 acaataatgc tatccagtat tttaactagg ctgccttggt cgttaactag aagaagcata
     7741 gaaatatgat gttgctctat gattaaggtc ctagtcttaa aagaggctag gacaatatcg
     7801 gcctgctagc tgctgtcggc gtcttgttga ttgactagat tacaaaggct agaccaagta
     7861 gcaggcccag gccctttagt tgcaagggta ttagccccaa aaacaataat aaataacaat
     7921 tgtgtgaatc gaaaggaaaa ggagtttacg agaactcgag gtatgatact atgaaaatgt
     7981 cgtttcgctg gtatggaaag catgatccag taagtttaga ggaaatcaag gccattcctg
     8041 gtatgcaggg aattgtaaca gctgtgtatg atgtaccagt tggtcaggct tggccactag
     8101 aaaatatcct tgaattgaag aggatagttg aggctgcagg ccttgagatt tcagtcatcg
     8161 aatcaattcc tgttcacgag gacatcaagc aaggaaagcc caatcgtgat gagctgattg
     8221 aaaattataa gacctctatc atcaatgttg gtaaggcagg tattcctgtg gtttgctata
     8281 attttatgcc agtgtttgat tggactcgct cagatcttaa ttacccattg cctgatggat
     8341 caacctcact tgctttttta aaggcagact tggcagatgt ggatcctgtg gcagatgatt
     8401 tgaacctacc gggttgggat ttttcttact caaaagaaga gatgaaggct attattgagc
     8461 attatcgtca tcatatttcc gaagaagacc tgtgggctaa tttagattat tttattaagg
     8521 ctattatgcc aacagcagag gcagctggcg ttaagatggc tatccaccct gatgatcctc
     8581 cttatggtat ttttggctta ccacgtatca taacaggtca aaaggctgta gagcgcttct
     8641 tagaccttta tgattcccct aataatggga ttaccatgtg tgtgggctcc tatgcttctg
     8701 atcctcaaaa tgatgtgatc gctatgacgg agtacgcgct taagcgccag cgtattaact
     8761 ttatgcatac gcgtaatgtc actgctggtg attggggctt ccaagaaacc gctcacttgt
     8821 cacaggctgg tgacattgat atgaatgcta ttatcaaatt attggttgat tatgactggc
     8881 aaggaccact tcgtccagat catggtcgtc gtatctgggg agatcaaacc aaaacccctg
     8941 gctatgggct gtatgaccgg gcacttggtg cgacctattt taatgggctt tatgaggcta
     9001 atatgcgtgc agctggaaag ataccagatt ttggcattac tgtaaaaaca gttggagata
     9061 aatagaaaaa ggggcatgag atgagtcgag ttattgaatt taaggacaag gttgttgtga
     9121 tcacaggagc tggcggtgtc ctttgtggca gtatggcaaa ggcatttgca aaagcagggg
     9181 ctaaggtggc actgttagac cttaaccaag aggcggcaca ggcctttgtt gatgatattg
     9241 aggcagaggg tggtattgca aaggcctatc aggcaaatgt attgtctaaa gaaaacctag
     9301 aggccgttcg tcaggcagtt ttagcagatt ttggtccagc agatatttta gtgaatggcg
     9361 ctggcggaaa cagccctaag gcaacaaccg ataatgagtt tcacgacaca agcctgccag
     9421 aggatacaaa aaccttcttt gaccttgatg aagcaggtat cagctttgtc tttaatttaa
     9481 actatttagg caccttgttg ccgacgcaag tctttgctca ggatatggtt ggtcgtaagg
     9541 gggcaaatat tattaacatt tcttcaatga atgcctttac gccattaaca aagatcccag
     9601 cctattctgg ggctaaggca gccatttcca actttaccca gtggttggct gttcattttt
     9661 ctaaggttgg cattcgttgt aatgccattg ctcctggatt tttggtaacc aatcaaaacc
     9721 gtagcctcct tttcacagag gacggacagc caacggctcg tgctgaaaaa atccttaaga
     9781 atacaccaat gggacgcttt ggtgaggcag aagaattaat tggaggcctc tttttcttgg
     9841 ctgatgagca gtctgcttcc tttgtgaacg gcgttgttct gccaattgat ggcggatttg
     9901 cagcttattc aggcgtctaa gctaaaaaat aaaccacttg agaactcaaa ctgcaatgcc
     9961 tcaagtggtt tttctatcgt gacagcttgc tttgtagcca agctgccatt aataaaggta
    10021 tgatgatttg tggcttctat tgttccttat cactctagcc ttttttagca atcaacaagt
    10081 aatgatagct tttaaaaatg aaacgctgct tgattaggat ttatgattga cagcgttttc
    10141 ttactgtgtt agaattaatt catcagatga tttggaggtt ggaatgacag ctaaaactga
    10201 acaatttgtc ttttgtgtgg actcagatgg ctgcgcaatg gacaccatga cttataagca
    10261 tcagctcttt tttggtccgc ttgcggcgga ttattttgcg gtagcagacc aagcgtcttt
    10321 cttaaaagag tgggatcgca ttaatcttta ttcgcgtaca cgcggtgtta accgctttgt
    10381 tgggcttgtt atggggctag aatacgcagg agttacaggg attgacgctt taaagcaatg
    10441 ggtacaacac actgcctcat tatccaatca gtctctggag gcggagcttc ttaagcgtcc
    10501 tagtgatgac ctgcaaaagg ccttggactg gtcaaatgag gtaaaccgtc agattgaggc
    10561 ctacaaagga gaggcattgg catttctagg agctttagct gctcttaagg ccttgcacca
    10621 gcttggccag gtttttgttg tcagctcagc taataaagag gccgttcaaa aggaatggca
    10681 ggatcaaggc ctgatgacac atgttgatgg cttgtattgt caggatcgtg gcaaaaaaga
    10741 ggctgtcata gcacagctca ttgatgaagg atatgtgaga gagcgcatga tgatgatagg
    10801 agattcacca ggtgatctag cagctgctga gcaaaaccag atcacttttt ttccaatcct
    10861 cgttggtaag gaggctagct cgtggcagga tctgtcacat gctgctgaag cttttacaac
    10921 tggtgacttg acagagcttg atgtcaagag ccttacagaa gccttctggc gtaatcttga
    10981 taggtaggca ggtagctgac cagtggagct gagcctgtta gggcttggta gcaggttgct
    11041 gtagcgccat tcattaaaac agaaaagcaa gcagagaagg ctttagttga aaggaagtac
    11101 aatgacacat ttagtagatt taagaaaaaa accatatagc ctagacgaag aagctatttg
    11161 ctgggtggag gataccattg cagcaatgac cttggaggag aagataggtc agctatttgt
    11221 taatatgggg gctagtcgat cagaggatta tttaactcag gtgcttgagg attatcatat
    11281 tgcagctgtt cgctacaata aaggcatggc ttcagaaatt tgggatcaaa attatatttt
    11341 acaaaccaaa tccaagattc caatgctcat tgctgccaat acagaggctg gtggtgatgg
    11401 tgctgtcaat gatggcacta aggttggtga tgaaatcaag gtagctgcga caaacgatcc
    11461 taaatacgct tatgaaatgg gacggattgc aggactggaa gcgtcagctg ttggctgtaa
    11521 tgcctccttt gcgccaattg ttgatttgac gcgtaattgg cgtaatccaa tcattgctaa
    11581 tcgcaactgg ggggtaaatg ttgatcaaat cattgagctt tccaaagagt atatgaaggg
    11641 gattatggaa tatggtatca tgccctttgc caagcacttc cctggtgatg gtattgatga
    11701 gcgtgaccat catttgtcct ttgcctcaaa cccaatgacc aaggaggagt ggctatctag
    11761 ctttggacgt atttatggcg agcttgcaga ggctggctta cctggtatta tggcaggaca
    11821 tattcacctg ccaaatgttg aaaaggccat gcaccctgag cgtgagctag atgatatgct
    11881 tccagcctca cttaataaaa ccctcttaga tgagctgctg cgtggtgagc ttggctataa
    11941 tggtgctatt gtgactgacg cttcgcatat ggttgcgatg acagcctcaa tgccacgtcg
    12001 cttattgtta ccaacagcga ttgaggcagg ctgcgatctc tttttattct ttaatgaccc
    12061 agatgaagac ctacaatgga tgaaagaggg ctatgaggca ggaattttaa gtgacgaacg
    12121 ccttcatgac gcccttcgtc gtacgcttgg cttgaaagca aagcttggac ttcatcgctt
    12181 tgaaggacac cgagaagata ttatgctgcc taaggacaag gcgatggtct tgattaacac
    12241 accagaggct caagcaattg cagatgaggt tgccgacaag gccattaccc ttgtgaaaaa
    12301 caagcaggca gggattttcc cggtaactcc agagcgctac aagcgtgtgc tgattgttaa
    12361 cgtggagggc tataagggtg gctttggtgc tatgattgca ggacagaaga aacgggcctc
    12421 agacattgtc aaggaattgc tagaggcgcg tgggcatgag gtaactgtct gggaatcaac
    12481 cgaagagcga atcatgcagc taccagagga agagcgtgca gcggctattg ctaatgttta
    12541 tgcacaaaag cagccgattt caaacattac agagcattat gatttaattc ttaatttggt
    12601 ggacgtcaat tctggaggta cagttcagcg tattatctgg ccagctgcta agggaacacc
    12661 ggatcagcca ttctacgtcc atgaggtccc aacaatcgtt gtttcagttc agcatgcctt
    12721 tgcccttgct gatatgccac aggttggtac ttatattaat gcctacgatg gcaaggacaa
    12781 cactatgaag gctttggttg caaaattagc tggtgaatct gaattcactg gagtgtctcc
    12841 tgttgatgcc ttttgtggct tgattgatac ccagctatgg catagcttct gaggttgcta
    12901 caggataagt agaggcttta cgtgttctgc ggtgattgct ctgaatgatt taaaaagatt
    12961 tcaggataaa acctgttaat cagccccttg tagctgcaga aatagcccca taatccctgt
    13021 ggtggggagt tttatccgat atggagatga tagagcctgt taatcctaaa gaaaagctag
    13081 agggtcattc tagcttttct ttttgtgcct aatgctcaac cttgcttcag atgatagaca
    13141 agctataagc ttgttgataa gtgaaacaat tgaacagata atgtttttta gagatgatat
    13201 attaagaata attttaaatt atgaaaaaat ataatatatt aatgat
//
LOCUS       DARYLJ010000050        13062 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYLJ010000050 DARYLJ010000000
VERSION     DARYLJ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13062
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..96
                     /locus_tag="TU746_001610"
     CDS             <1..96
                     /locus_tag="TU746_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL0891929.1"
                     /translation="ITDYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
     gene            complement(154..1203)
                     /gene="citC"
                     /locus_tag="TU746_001611"
     CDS             complement(154..1203)
                     /gene="citC"
                     /locus_tag="TU746_001611"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL0891930.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1470..2533
                     /locus_tag="TU746_001612"
                     /pseudo
     CDS             1470..2533
                     /locus_tag="TU746_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2619..3503)
                     /gene="citG"
                     /locus_tag="TU746_001613"
     CDS             complement(2619..3503)
                     /gene="citG"
                     /locus_tag="TU746_001613"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL0891931.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3496..4191)
                     /locus_tag="TU746_001614"
     CDS             complement(3496..4191)
                     /locus_tag="TU746_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0891932.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4344..5747)
                     /locus_tag="TU746_001615"
     CDS             complement(4344..5747)
                     /locus_tag="TU746_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL0891933.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            6129..6473
                     /locus_tag="TU746_001616"
     CDS             6129..6473
                     /locus_tag="TU746_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891934.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6491..6886
                     /locus_tag="TU746_001617"
     CDS             6491..6886
                     /locus_tag="TU746_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL0891935.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6936..8057
                     /locus_tag="TU746_001618"
     CDS             6936..8057
                     /locus_tag="TU746_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL0891936.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8239..8547
                     /gene="citD"
                     /locus_tag="TU746_001619"
     CDS             8239..8547
                     /gene="citD"
                     /locus_tag="TU746_001619"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL0891937.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8535..9422
                     /gene="citE"
                     /locus_tag="TU746_001620"
     CDS             8535..9422
                     /gene="citE"
                     /locus_tag="TU746_001620"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL0891938.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHATRAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9424..10956
                     /gene="citF"
                     /locus_tag="TU746_001621"
     CDS             9424..10956
                     /gene="citF"
                     /locus_tag="TU746_001621"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL0891939.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10949..11509
                     /gene="citX"
                     /locus_tag="TU746_001622"
     CDS             10949..11509
                     /gene="citX"
                     /locus_tag="TU746_001622"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL0891940.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11540..12931
                     /locus_tag="TU746_001623"
     CDS             11540..12931
                     /locus_tag="TU746_001623"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL0891941.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3835 a         2609 c         2877 g         3741 t
ORIGIN      
        1 attacagatt acatttttta ctacaacaac aaacgcatta aagcaaagct aaaaggactt
       61 agccctgtgc aatacagaac taaatccttt cactaatatg tcgtgtccaa cttttggggg
      121 tcagtacaca gttagagagg gggtagttgt tggttaataa tgcttaaggt ctgttgctgc
      181 tttgatctta gttatcgtgg gctgagcagc ctcgctccta aaaaagtcaa gtgaggtctt
      241 aggaaggagt agctctaaga gagcataatc atcgtccttg atggcctgtc tggcaagaga
      301 ggcgctgatg attttgcctt ctgcaaaggt ttttctaggg ataacctgca catcaatgct
      361 atagcaaggc agctgcttga gcatgacagt gttgtaatgc tgtgtgacca tgctagtagg
      421 ctcttcgcca acataacgac tcttgatttg gagtttttct gcaatgtgac ggaaaatgac
      481 aatatccaat ttagcttgac tatcaataac tgctagctca tctttttgaa aataagcagg
      541 aaaggttgcc tgactaatca tgtaaggtcc actatcgtgg tatatgatat ttgctaggtg
      601 tgcagttcct ttgatgatta attcctttcg gatatggtag gggatcaggc tactgtcttg
      661 actgaccata aagagatgaa cgagctcgtt gtcagcgcag gccttttcaa tcagatgcag
      721 atgaccaagg gtaaatggat tagcatttaa aacgattgct gcggtctttt gaggactgat
      781 ctggggcttt tctagctgtg acaggtagtg ctcaaagccc ctttttttat tttctaaaaa
      841 acaaagagta tcatcaacca ttgcaatgac atgaaagcca agacttagca atagaggggc
      901 agctgctatt ttagtgtaga taaacagatg atgatgccca cgtgagtagg cctcctcaat
      961 cagatgtgag acaatgtgat taagtaagcc ttctccttgg taggcttgat caacagctaa
     1021 gcagcgcagg ctattgccgt acaaagagcc agtagcaata ggctcgcctt gctcgtcaat
     1081 aatagcacag gtataatcta aatgagggtc tcttctaatg tgctgtcttt gtaacaaacg
     1141 atcaattttt gctttttgct gcttgtcaaa gggaaaaata tgctgtatca agtgctgcgt
     1201 catatgctca cctcttatta cgaaattatc ctcttgcctt tattatagca cgctataggg
     1261 cttattctta agcatcttag ctggtttatg aaaagaatgc acaaaaaaga catcaatgac
     1321 ctattgtctc tgatgtcatt atgatatgat taggactttt agataaatga ttaaggtatg
     1381 gaggatttaa gcctgcaaaa ggtggcaata ataattctga cttatgctat aatagagcta
     1441 ttgatattaa gggggataaa ggggctggta tgctttcgat tctaatgact ttatttgttg
     1501 ggacgctggg agggcttgtt gctaagcggc tgagtattcc tgcccctttt atgattggca
     1561 gtatggtagc tgttgcccta gcttctatcc tgacaaagca ggtagaggct attaacccca
     1621 tgaagatttt tgctcagatt attagtggtg cctatattgg ccaaagcgtc agcaaatctg
     1681 acctgcttaa tctgcccaag ctagccaagt ctattattag tctcatgtcc ttgttcacgc
     1741 tgaatatgtt tcttcttggt ggggtatttg tttactgctt tgatcttgat cctgtaacag
     1801 ccttgttgag ctgtttacct ggtggcatta tggacgtttc tcttatggca gttgatatgg
     1861 gagcaaaggc tgatatagtt gcgacattac agtcggctcg actggtcggt atgctcttgt
     1921 ttcttcctgt ttgggtgacg ttttgggtca atcgctttga cccaaaagca aaagctacta
     1981 aaaaaaaaag atagtcaaaa gcgctagctc ccaagataca agaccttcta ggaaagagca
     2041 gctatggaat aatgtccagg ttttaagcat tgctaccatt ggaggtttga tcggtttagg
     2101 gctaaagata cctgtaggcg ctctgattgt ttctttgctt ttttcaacag cactgaaggt
     2161 gcttcggcaa acaagtcaaa tgccaagtac acttcgttat atagcgcagg tttttgctgg
     2221 ctctattatt ggaacaagct ttactcagga tagtttgctt caaatgggac gtctgattgt
     2281 tcctattctt ttacttttga gtagctatct gatcatcaat ctcttttttg gctatatcat
     2341 gtataaaaaa ggtatcttgg atttgcaatc ggcactcttt gcctcatcgc ctgctggtgc
     2401 gacagacatt tcactattgg ctggtgagct tggcggagat atgcctaaaa tcgctggtat
     2461 tcaaatcagt cgaaccctct atactgttgt catcatgccc ttgttggtta aatggctcat
     2521 tagtatatgg taaacagaaa agcccctcag agcataaacc agagatacct agtcattacc
     2581 aaataacata tcaaggatct tgttcaggct tggagctgct ataattgatt ttctaaaaaa
     2641 gcaaagtaga ggcttagcac tagcagatca gcagtccctc caggactgag atgcttttgg
     2701 atcagcttgt cgttgtaggc tgacaaggca gcctttaagt cagcagtgct caaagagctg
     2761 ttgtgcaata gcagcatgtc ctgtttgact tgccgccaag ctttgatgcc tcctcggtga
     2821 atcaggttgc catcttccac aatagacatg aggtaaacca gcagttgcag ttgagcggtc
     2881 tcctgatcag tgctgcgaag gctcttgcgc aaaaaaggca gcgccttgtg agcaattgta
     2941 ggatagccct cgctggcttc tcctctaggg ccctttatac cgtaatctag aaagagcttc
     3001 tcaccatagg tgagctcttt ttttaggtct aagctaccaa aatcagtctc aaggagatga
     3061 gctgttagag gcttgacaag ctgacaaata gccagactat cctcctcagt aaaggctgtt
     3121 acatggtcca agagctgtgg ttgatcggca agatacattc ccgttgcccc aagcagaagt
     3181 gctaaggaaa aattgactcc cttatgggta ttgactccct tagttgcgct gaacatggct
     3241 tgctcagcct caatgcctga ggcacgcaag cgctcaaaga tcagaccagg atcttcctta
     3301 gcatggtaaa aaccaatgtc taaataaatc ttaaaaaagg gggctaaggc cagagcgcta
     3361 tcaacaaagg ttaagaagct catgtcatca tgagccccgt tatcaagctg atccacaagc
     3421 ccaggcttag gagataagga cacttcgtaa agtaaagcct ttagagcaag cctgctaata
     3481 tcatcaaata ccttcttagt catcctgacg cctgctcatt tcctgtagga taaattctag
     3541 tgagctgttg aggtgctcat gcgtaataag ggtgatttgc tcgtggtcac gatttttcat
     3601 gccacgataa atcatccaat gctcagataa agcgcgtttt cgtctttcta gggaagagat
     3661 cgaaattttt ctaaagtaaa caaggtaggt ctgcaattca gtgacaattt cttttaatct
     3721 gaccatctga ctatagctgt aaatcagatt attaaagctg ttgaaattat ctagaattct
     3781 gttgagatcg tcatcttcta taaaggtttc acaatcagcc aacaaatcat gcatgacctg
     3841 aaaatcttcc tctgtcatca aatacatagc ggtgcttgtt gccagtgttt caagcgcttt
     3901 tctgatttca aagatttcac aagcatcttg aatactaaca cccttgacaa taatgccttt
     3961 tttaggaata tgctctacca aatgctcctc tgataacaat cctagagcgt acctgattgg
     4021 tgttctgcta atatttaggg caatggaaaa ttctttttcg ttgatacgac tgccagcagg
     4081 aatttgtctt aaaataatag ttttctttag ggcgttataa aaagctattt tcaaagggat
     4141 attgcgggat aggtcaagat tattctttac tgcttcgata ataggattca tataatctcc
     4201 ttaatgttca tatcatgata ttattatact gaaaatcatt actaatgaaa ataataatta
     4261 gcctcctaaa aggcgaaagc catgctcgtg aaagaacatg gctttcatta gcccacacta
     4321 cagtcctaat aatagctcgt gacctattgt ggaatgtaaa gcggcatttg tcccattgca
     4381 ataatggtta caacaaagat aataaagata ataatcgcgt atttagcagc ttctttttgc
     4441 cattctccca tatcaagccc agtaagacga agaagcaggt aaataaaggc caccaatgga
     4501 ctgagcaaat ggaaggcttg tcccatcaga gaagcaagag ccatcgccat gttgctaaag
     4561 ccatattcag ctccagcctc cgctaagact ggcaaaatac catagtagaa gccatcattt
     4621 gagataaaga aagtaccagg agctgaaatc agggcaataa caagtcccca gaagccagcc
     4681 aattgctttg gaataatcgt tgcaaagctt tgagcaagag cactagccat accagagcct
     4741 tggaaaagtc ccatgaagat accagcagca aaaaccagaa taacaacctg aacagcatca
     4801 ccggcattat caccaatacg ctttgtttgg tcctttagga caggatagtt aacaataagg
     4861 gcaatacagg ttcccactgc aaataaaaga agtggtgcca tagcaatagc cttatagaaa
     4921 gagccagcaa ccagccaagt gattaagccg atggttaaga tagcattaaa ggcaaagttt
     4981 ttaggacgac ggatagaaag cgtatctgga tctgtaatgt ctgttagctt acgcatttcc
     5041 tcttcggtca aatcaacaac accaagtctt gcacgctcct tgcgtcccat gcttggcgca
     5101 acccaacaaa tgacataaag aagagacaaa accataccag gtgcaaggta tccaaggatt
     5161 tcaggtccca cactaagcac agacatggca cgcgcagttg gaccacccca aggaagcagg
     5221 ttcatgatag tgttttgcag gataatcaag acaccaagat tcatgatgcg catgtttaat
     5281 ttcttataga ttggtaaaaa agcagagcag caaatcaagg ttgttgttgt accatcacca
     5341 ttaagtgaaa cagctgctgc aacaattgca gttgccatca agaccttcat cgggtctccc
     5401 ttagcaaagc gaatcatttt ttcagtaatc gggtcaaaca agccagcatc tagcataatg
     5461 gaaaagaaca ggatcgcaaa aagcagcata atacctgtct tagcagtgtt attaataccg
     5521 tacatgatca taggaccaat agctgtcaga tttttagcaa gcccatcctc accaacaaag
     5581 gcaacaaatt tggcgtctga tgtaaaatca gcagagcctg ttaatataac agcaattgtc
     5641 attatcaacg gaatcatgac cagagctgta aaaggggtca tttttttctt catgacgaca
     5701 tacatgaaga taataatcat agcataagct agaactgtta ataacatatt gttatctcct
     5761 ttttgatttt atgacttcag tataaatgaa agcgttcgca aaagaaatac ctccatgtac
     5821 ggaaaaacac aaaaaaaaca ttttgaaagc agatcctgaa aaaataaatg gttacattaa
     5881 tgtttttcaa cagcagttag ttgctcttat cttcagtaat cgcagtgtgt ttcagcattt
     5941 tttaaaatca gtcatattta ttttagttaa ctgtttttat aaaaatggtt aactaaaata
     6001 agaaaatcct tgaaaatgtg aaagcgctct tagaaagaac acaaaaaagc cattccaaaa
     6061 ggatgaggtg gtatataata agcatagaag cttcccattt gtgggcaaac taagaaagga
     6121 ggtagcttat gcagtttttt caaaacatgt ttagacgctc taaaaaagag gcagccacaa
     6181 gccatcaaga cagagaaaat aagcctgaat ttccgttaga tgactgggag ccagtgccta
     6241 gctacattgc tgcagataaa aaggattatc agacagttag tctgattgcc agtgccattg
     6301 cagctggcga gcaagctagc agtcagttta aggtaaaacg aatcctacag cgcaatcctg
     6361 aggccttaac cgtatcctta atagcatcaa gcattgcagc tggtgtttat ccagagagtc
     6421 aatttctggt taggtccatt tatagtaaga aagtaaacgt tagccacaaa tagtaaaagg
     6481 agaaaagatt atgttgcgta agtttaaaat taccattgac ggaaaagagt acctagttga
     6541 aatggaagaa atcggtgctc cctcccaagc cccagtagta cctcctgttc aaccagcagt
     6601 agctccagcc cctgtagccg aaaaaaaggc agcagaagct ccgcaagctc cagcagcacc
     6661 tgtatcagca ggggcagatg caatgccctc acctatgcct ggtattatct taaaggtttt
     6721 agttaatgtt ggtgatgtcg tacatgaaaa tcagcctcta ttgattttag aggctatgaa
     6781 aatggaaaat gagattgtcg cctcaacagc tggtacagtc acagggattc atgttactgc
     6841 aggtcaggtg gtcaaccctg gtgaaggctt aatcaccatt agctaatcct aagtcgtgtc
     6901 ttgatttaaa atgttgtaga aaaggaagta catttgtgga aacattaatt gcaggagtaa
     6961 cctccatcac tattcctcaa atcattatga tgcttatcgg tgctgtctta atgtatctag
     7021 gaataaaaaa agaatacgaa ccaaccttac tagttcccat gggactgggt actattttag
     7081 tcaactttcc cggcacagga gtcttaacac aggttgttaa tggtgttgag caagaagggg
     7141 tctttgatgc cttattcaat tttggaatcg gtacagagct gtttccatta cttattttta
     7201 tcggtattgg tgccatgatt gactttggtc ctttacttca aaatcctttc atgctattat
     7261 tcggtgcggc agctcaattt gggattttct ttgttgtcgt tgtagccgta ttagctggct
     7321 ttgatattaa ggaagcagct tcaattggta tcattggtgc tgctgacggt ccaacatcaa
     7381 tttttgtagc aaaccaattg gcaaaggatt tgctagggcc tatcacagtg gcagcttatt
     7441 cttacatggc tttggttccg atcattcagc cctttgcgat caagctagtt actaccaaaa
     7501 aagagcgtcg tattcgtatg acctataagg ctgagaatgt gtcacaatta acgaagatcc
     7561 tctttcctat tgtgatcaca cttgtagccg gctttattgc tccaatttcg ttaccattgg
     7621 ttggtttttt gatgtttggg aacctgcttc gtgaatgtgg tgtcttggac cgattgtcac
     7681 agaccgctca aaacgaattg gtcaatatca tcagtatttt actaggacta accatctcta
     7741 tcaaaatgca ggccgagctt ttcttgaatg tgcaaaccct gcttattatc atttttggtc
     7801 tgttggcctt tatcatggat tcgattggtg gtgtgatgtt tgccaaattc ttgaatttat
     7861 tccgtaagga aaaaatcaac ccaatgatcg gagctgctgg aatttcagcc tttccaatgt
     7921 caagtcgtgt gattcaaaaa atggccactg atgaggatcc gcagaatttc atcttgatgt
     7981 atgctgtggg tgctaatgta tctggtcaaa tcgcctcagt tattgcaggt ggcttgctgc
     8041 ttgcttactt tagctaagaa aggacgtgct tatgacaatc aatatagacc atttgatcca
     8101 atcctttgag ctaatggcac ttggaatggc aggagtattt gttgtattag gaattctcta
     8161 tattgtagca gaggctctga ttaagctatt tccagtagaa aaataataga atatgatcta
     8221 aacaaggagg tcaatcaaat ggagatcaaa caaattgctg ttgctggttc gcttgaatct
     8281 agcgacatga tgataacaat atcacctaat gatggtcagg gaatcgtttt ggaattggat
     8341 tcaagcgttg aaaaacaatt tggcaatcat atcagagcat taatcaagac aacacttgcc
     8401 aggctgggcg ttgagtcagc aacgatcgaa gctgttgata agggagcctt ggattgtacc
     8461 attcaggcaa gaacaattgc agcagtccat cgtgctgctg gagttgagca ttacaactgg
     8521 aaggagatcg actcatggaa cgcttaagaa gaacgatgat gtttgttccg ggcgctaatg
     8581 cggctatgct aagagatgca cccttgtttg gagcggactc tatcatgttt gatttagagg
     8641 attcagtttc cttaaaagaa aaagacacct ctcgcgccct tgttcatttt gccctaaaaa
     8701 cctttgatta ttcaaatgtt gagacagttg tgcgcgttaa tagcctagac tcttgtggtg
     8761 ctctggatat tgaggcagtt gtgttagcag gtgttgatgt tattcgcctg ccaaagacag
     8821 aaactgccca ggatattatt gatgttgagg cagtcattga gcgtgttgag cgtgacaatg
     8881 ggattgctgt tggtcgtaca cgcatgatgg cagctatcga gtctgcagaa ggggtcttaa
     8941 aagctcgtga gattgcaaag gcctcaaatc gtctcattgg tattgccctc ggcgcagagg
     9001 attatgtgac taatatgaaa acacgtcgct acccagatgg acaagaatta ttctttgccc
     9061 gcagcatgat tcttcacgca acacgtgctg ctgggattgc agcaattgat accgtttatt
     9121 cagatgtcaa caatacagaa ggcttccaag ctgaggtgcg tcatatcaag caattaggct
     9181 ttgatggtaa atctgtcatc aaccctcgtc agattccatt ggtaaatgag atttatacac
     9241 caaccgaaaa agagattagt cacgccaagc aagtgatctg ggccattcgt gaggctgaaa
     9301 gtaagggatc aggtgtcatt tcattaaatg gaaaaatggt agataagcca atcgtagagc
     9361 gtgcacagcg tgttatcgct ttggcaacag ctgctggggt attaacagag gaggacattt
     9421 agcatggtta aaaataaact tggtcgtgat attcctcagg agtatgctga tcactatgga
     9481 gtatttgaag gagagctagc acgtatcact agctacaatg aatcaagccg ccgcattaag
     9541 cctgtaaagc caggtgacag taaattgctt ggctctattc gtgaagctat tgaaaagaca
     9601 ggcctaaaag atggcatgac catttcattt caccatcatt ttcgtgaggg ggacttcgtc
     9661 atgaatatgg ttcttgatga gatagccagc atgggaatca aagatttagc tattgctcca
     9721 agctctattg ccaatgtgca tgagccatta attgagcaca ttaaaaacgg agtggttaca
     9781 agcattacct catcaggttt acgtgataag gttggggcag ctatttcatc agggattatg
     9841 gaaaagcctg ttgtgattcg ttctcatgga ggacgtgctc gtgcgattgc tagtggtgat
     9901 attcatattg acgttgcctt tttaggagca ccaagctcag atgaatatgg taatgtcaac
     9961 ggtacgattg gtaaggctac ctgcggctca cttggctatg ctatgatcga tgccaagtac
    10021 gcagatcagg tggtggtgct gacagatcac ctagttgatt atcctaacac cccaattagc
    10081 attccgcaaa ctgatgttga ttatgtcgtg acagttgatg ctattggtga tccacaagga
    10141 atcgctaagg gagcaacgcg gttcaccaaa aatcctaagg agctcctaat tgccgaatat
    10201 gccgctaagg ttatcacaca gtcgccttac tttaaaaatg gcttttcctt ccaaacaggt
    10261 acaggaggag cttccttagc agtgactagg ttcatgcgtg aggccatgct tcaagaaaat
    10321 atcaaggcaa gctttgccct tggaggcatt acaaacgcta tggtagaatt gctcgaagaa
    10381 ggattagttg agaaaatcct agatgtacag gattttgatt acccttcagc agtttcgctt
    10441 ggtaaaaatg ctcagcatta cgaaattgat gctaacatgt atgcctcacc actaagcaag
    10501 ggatcggtta tcaatcaatt agacacctgt attttatcag cgcttgaggt tgacactaat
    10561 ttcaatgtta atgtcatgac aggttctgac ggtgttattc gtggggcttc cggagggcat
    10621 tgtgacacag cctttgctgc caaaatgagt ctggtgattt caccccttat ccgcggacgc
    10681 attccaacct ttgtagatga ggtaaataca gtaattacac ctggaacaag cgttgatgtg
    10741 gttgtcacag aaataggtat tgctatcaat ccaaaccgtc cagatttgat agagcatttc
    10801 aaggacttga aggttcctca atttagtatc gaagaattaa aagaaaaggc ttactcgatt
    10861 gttggaacac ctgatcgtat ccaatacggt gataaggttg tagctcttat tgagtatcgt
    10921 gatggcagcc tgattgacgt tgtctacaat gtctaaggaa ttgattttca aggggaaagc
    10981 tgttacccta gctgatatgc taagggcacg cgaggacaga agccttcgtc aaggaaagct
    11041 tttaacagaa ttctcaaacg aaagcctgct ttctgtgacc atgaatattc caggccccat
    11101 taaaacgtca cctgctttac ttgaggtatt tgatagtgtt atcaaggcaa tcctagaaaa
    11161 gctgtctggc aatcagatca gctatcagct tcgtttgctg ccaaaaacgg gttatgaata
    11221 ttaccttgtg acagccttag atagtcaggc attaaagctc aaaatgattg agcttgagac
    11281 tgatttaccg attggcaggc taatggattt ggacgtttta gtgctgacaa atcagctgcc
    11341 aacccctatc agtcgaacag ccttaggctt tcctcctcgc agctgctatc tttgctcaaa
    11401 agaggctaag gcttgtagta gaaatcgcag tcactcggta gcagacatgc agacagccct
    11461 tgtacactta ctccaatcat tttttgacgg aggcaatcag ctcagttaga ctcaacggta
    11521 ttcttataag gagaatgata tgacaaaaat ccgtataaca gaaacagttt tgcgtgatgg
    11581 tcagcaaagt caaattgcta cccgcatgac tacaaaggaa atgattccga ttttagaaac
    11641 actagataat gctggctatc atgccctaga aatgtgggga ggagctacct ttgattcttg
    11701 cctacgtttc ttaaatgaag acccttggga gcgtctaaga accattcgta aagtagtcaa
    11761 gaaaactaaa ttacaaatgc tcctgcgtgg gcaaaatctt ttgggctatc gtaattatgc
    11821 tgacgatgtc gtccgcagct ttatccaaaa atcaattgaa aacggtattg atattgtgcg
    11881 catttttgat gccctaaatg atccacgtaa tctagagaca gctgtttcag caacaaaaga
    11941 attcggtggc catgcacagg ttgctatttc ttacacaaca agtccagttc atactatcga
    12001 ttattttgta gccttagcaa aagcctatca ggctattggt gcagattcga tttgtatcaa
    12061 ggatatggct ggtgtgttaa ccccggagac cggttatcaa ttagtgaagc gtatcaagga
    12121 aagcattgct ctaccacttg aggttcacac gcatgctacc agtggtattt ctgaaatgac
    12181 ctatctcaag gtcgtagagg ctggtgcaga tattattgat actgccatat cctcatttgc
    12241 cggcgggaca agccagccag caacagaatc gatggttatt gctttagagg acttggggat
    12301 tgataccgga gtagacatga caaggctgac aaaaattgcc gagtatttta atactatccg
    12361 agatcactac agggcagagg gcattttaaa tcccaaggtt aaagacactg agcctaagac
    12421 cttgctttat caggttcctg gcggcatgct gtccaatttg ctaagtcagc ttaaggaaca
    12481 gggactctct gacaaatatg aagaggttct ggctgaggtt ccaaaggtta gagctgattt
    12541 aggctacccc ccactggtga ctccgctatc gcaaatggtt ggcacacagg ccttaatgaa
    12601 tgttatttca ggtgaacgct acaaggttgt cccaaacgaa atcaaagact atgtcagagg
    12661 actttatggc caacctcctg cgccactagg tgaaggtatt aaagagaaaa tcattggtga
    12721 tgaagctgtt atcacttgtc gtccagcaga tttgattgag ccacaattgc ccttgcttcg
    12781 tcaagaaatt gcaggctatg cctgctgtga ggaggatgtg ctgagctatg cctctttccc
    12841 tcagcaggca aaggatttcc taggacgcag agaggatccc ttttatgata tcccagttca
    12901 gtacgtcacc gttgatatag caatggatta atcaaaagaa taaaaagcaa gataactaat
    12961 aaaatcaatc tcctaattat tagtcaaagc tacctaccaa taaactcctt aatcagaacc
    13021 acccgtctaa tgaggtgccc ccaaaaggtt agtccaaaac tt
//
LOCUS       DARYLJ010000051        12359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYLJ010000051 DARYLJ010000000
VERSION     DARYLJ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TU746_001624"
     CDS             complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TU746_001624"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL0891942.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2578..3231)
                     /locus_tag="TU746_001625"
     CDS             complement(2578..3231)
                     /locus_tag="TU746_001625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891943.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3271..3900)
                     /locus_tag="TU746_001626"
     CDS             complement(3271..3900)
                     /locus_tag="TU746_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL0891944.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3902..4903)
                     /locus_tag="TU746_001627"
     CDS             complement(3902..4903)
                     /locus_tag="TU746_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL0891945.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4936..5577)
                     /locus_tag="TU746_001628"
     CDS             complement(4936..5577)
                     /locus_tag="TU746_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL0891946.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5612..6406)
                     /locus_tag="TU746_001629"
     CDS             complement(5612..6406)
                     /locus_tag="TU746_001629"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL0891947.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6715..7149
                     /locus_tag="TU746_001630"
     CDS             6715..7149
                     /locus_tag="TU746_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0891948.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEADEADLDEGGI"
     gene            7149..8348
                     /locus_tag="TU746_001631"
     CDS             7149..8348
                     /locus_tag="TU746_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL0891949.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8394..8882
                     /locus_tag="TU746_001632"
     CDS             8394..8882
                     /locus_tag="TU746_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL0891950.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8897..9676
                     /locus_tag="TU746_001633"
     CDS             8897..9676
                     /locus_tag="TU746_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0891951.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9663..10484
                     /locus_tag="TU746_001634"
     CDS             9663..10484
                     /locus_tag="TU746_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0891952.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10884..11885
                     /locus_tag="TU746_001635"
     CDS             10884..11885
                     /locus_tag="TU746_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0891953.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
BASE COUNT         3478 a         2845 c         2448 g         3588 t
ORIGIN      
        1 agctcagggg ggattttaac ttattactaa tgtgcttgaa tggctatgat aaggccttaa
       61 aagatagctg cttaaagtca tttcccacct tttgatagag gtataagcct gatttttcaa
      121 gactcaattg accattaacc acctccttag cctgattgta tttgaccacc gccaacaggc
      181 cttgtttctt atcatggatc agctgaagct tactgtcatt tcgaagcacc tcaatacgtg
      241 cttcgctgca caccttgtca aagtctgctt tgctgatatt tggaagtagg gtgtaggcat
      301 agctatcact agcctgagaa tgagtttgac tgattgtgat aaagctttgg gagatgaggt
      361 ctttattgtt actatttgta ttaatctcag accaacagcc tgactgcacc tttcgcgata
      421 gcgctaatgc ggttggcttg gcaaaaaggt aaccaatatt agcttgaccg tctttagaaa
      481 gtagtaaaag actggtcaca tcatctcgat acaggatctc ctctgttagc gctgtctcct
      541 gcccattgat aaaaagagtg tagctgttgt ctgggttttc tttgcgttga tcaatggtag
      601 tagtcactgc ctgatgtgtc tgactagtga tggcggtgcc aagaaaaaca atttggtcat
      661 ctaagatcgt ccaagacttc ttggcactca ctgtcctatc ccaattttga aaatccataa
      721 cagctaaagc tgttttgtct cccgccttga tcgctccaac aaaggacgat ggcagggtag
      781 acatgcctgc tttttctttg gccttttctt tataatcatt ggttagcttt tttaaatagg
      841 ctactgtcac gtcctctcgc ctgacctctg cttccgttgt tccagccatc tttaaaggat
      901 taacagtcgg ccaaaagtgg tctgagtaat gacccaaatc actgttataa aggtaaaaca
      961 tgccatctcc tgtataccaa ccacgtgtat tttcatcgtt catggcttca aaattcagag
     1021 ttttgttgga atgcatggat aaagcaaagg caaaatcctt ttccgcattg tagtaggcca
     1081 atttatccat ctggttaaaa agagataggt agctcttaac tggactggct tggattgtgg
     1141 tatcctccaa gagctctttg aatagcttca tgtcatagta gcttgatagg ctctctaaaa
     1201 tagtctcctg attatggaag gccaaaacag ccttgatctt acccttgatc ctgattttag
     1261 cttgctctgg caatgcctca gccagtctta gcattcctct tagtgcttct aaggctgcct
     1321 gccttgagga ggcattttca cgactgatgg agcgcccacg actcatatcc atgagctccc
     1381 catgaaccat caagggcaag aaggcttgct caatccaatg agtcatgacc tctagctttt
     1441 gctggtctag gctagtagct aatagctgaa gtaatggtac cagctgagac aagccatcaa
     1501 taaggacatt gccataggct ccagtgtagg cgacattggt atggtcaata taagagccat
     1561 cttcataaaa gccctcaccc cttgatccct ttggctgaaa agcaaataag gtatctaggg
     1621 ctgctatact gtcttgaagc gctttcttat catgctttaa cagagcttca ataatcttca
     1681 ctcgtcccat atcaacaagg ttacccccaa tggccttaaa aggattcaca agggttaagc
     1741 gaaattgtct aggattagga acaaagtgag aaattccttt agtatagcgc ttgatctcct
     1801 cttgagtgac ataagggtaa atgaaggcta gggtattgac aatagctctt ggggtaccaa
     1861 tttcaaaatc ccaccaatta gccttgcctt caatatcctt ttgcggatga tagtaattaa
     1921 gtgtcagcca ggctaattta tccttgatca gtcttatcag ctccttatcc tgataatacc
     1981 tagaggctag gctactcacc tgcttggcca tttcctctaa acgcctacag gtagctgtca
     2041 tatgagacga ttgatgaaga tccgccaaat cactccaaag gtatgtgctt ttctgatcct
     2101 tggtcagatc agctagattc ttggtcacgc tgtcgtccag tttttggttt aatgccacca
     2161 tggctggact tgatcggtca aagttttctg ctcccaaaat cacctcacac cactttgtga
     2221 tcaaggaggt tgtttgaggg gcttctgctg ctaaaatctc aactggtacc gttgctactc
     2281 tttgcccctc ttgatccaac acctctaaaa gcgttttccc ctgcgccaaa ggaattaaaa
     2341 gaccattttc cacgcgcaca atgttgctgg actccgctgc aatctgataa tgatagtcag
     2401 ccatttccat gaggtagtgc ttatttaaag gcaggacgat ttgctcctct aagtaatgtg
     2461 aagcaatctt gatgtcatca cttggcttat caccagcctc tctcaaagaa aggttatcaa
     2521 agaccacctg tccatgaccg gcctcataaa agagctctag cttgatttga ttaaccttta
     2581 gcttagggat ataaagcttt tcttggtgtt ttttctcagt tcctgttgcc atcgaagcca
     2641 caagcgttgc tcttttgcag caccagaacc ttgctttatt tcttcaatga tacgcgcaaa
     2701 agcctgacct gttttatcct ttgtctcaat gtcaaaggtc agcaaatact gcttgtctgg
     2761 attgatggca acggtttggt gcacacagcc tctaaatctc tgattgccat cgctagtcat
     2821 tgtcagcttg ttatcagaga cagcaatttt aggacagccc tgactcttac tagcgtcctt
     2881 ataatccttc caatcatttg cagactcctt gctccaaagg cttgtacttt gatgctcttg
     2941 agcaggactg gtctgatcaa attgaggatt tttaagcagg ttatcacctg tgagaatgag
     3001 ctgctcccca agactggatt ccgtagctac tgacgacgcg tcttgagtgt ctggggagct
     3061 ttcttgagaa gcctcctcag tttttagtgg tgctttcttt accctctgaa gctccttgga
     3121 aatggctttt gctgctgttt tttcttctgc taagactgtt ggtgcccgaa ataaacaagc
     3181 tagtatgata ctagagcaaa cagaagatga tagttttttt ctttgcttca tctgatacct
     3241 ccttgctttt ttaatgtttt atgaccgact ttaacagcta ctcatgtaat ctgcagccct
     3301 tgctgtgatt gcctgaaatt gaccctgagc tgccaattga ttaaattctc ctccaactcc
     3361 cagcacctga gcacctgcgg caaaccagtc tgacacattt gtgacagtta cgccacctgt
     3421 taccatgaca tcaacctgcg gcaaaggaga tttgattgcc ttaataaagg acatgccaac
     3481 tgtggcacct ggaaagacct tgaccatctc tgcacctgat tccaaggcag tcacgacctc
     3541 ctcaatagtc atacagcccg gaatataagc aatagcatat cgatgacata ggcggcttgt
     3601 ctgcctgcta aagctaggag acacaataaa ttgagcaccc gctaaaatag ctagccttgc
     3661 tgtgacatca tcaagaaccg tcccagcccc gatcaggatc tctggatcat tgccaactgc
     3721 ttcacgcagg cctgcaataa cctgactggc aaagggatta gtataggcca cctcaatggt
     3781 tttgatccca ccttcaatac ctgctaggct gcaagccatt gcttcttttt tagaagctcc
     3841 ccgaacgact aaggctaatt tattggcttt tagccttaac atgatttctg attttctcat
     3901 attaccttct tacctctcgg tttcccttca tcaccctatc aacctgacta acaggaacaa
     3961 agagctgatc atcagcaact gtacacttaa gactagctgt cgcagcagca aaatcaagcg
     4021 cagcagcaat agcctgtcct ctcatcaatt gatataagca gcctgcaaca aaggcatcac
     4081 cactgccaac tcgttgcaaa acaggcgttg atagctcaat ggagcgatgt aactgcccat
     4141 cataggcata ggctaggtaa tgattgattc cttggtcatc gatgtgacgt tccgtgtgaa
     4201 aaatggcttt taagtgatat gcctcatata aggcagccaa gcgctccttg acagcacctt
     4261 gacctgcctt agctctatca aacatggcat gatcagcttg attacacatt aagggctcca
     4321 taccaaagat caggtctgca tactgtgcaa aatgagagaa caatgtcttt gcctccctga
     4381 ctgaaatcat cgagctgcga aaattcaaat caaaggaaac acagacctgc cgcttcattg
     4441 cctcaatagc cagctgctca acaaggtcct gactgacttt tcctaaagcc aaggtaatgc
     4501 cactaaaatg aaaatgagta acttcctcaa atagtttacc ataatccaga tcttttgggc
     4561 ccaataaact aaagctagag gcagagcgat cataagcgac ctgactagga cggcagccaa
     4621 agccattttc caaataataa ataccaaccc gatcaccaca ccattgcaca tgctctgtgg
     4681 caacaccgct ttgcttcaaa aaggcctcaa cgcttcgtcc aacctgatta tcaggaaggg
     4741 cagtcagcag gctactctct gctctaaagc cactaagcgt tcttgcaata ttaacctctg
     4801 agccaccata atacagctgt gcttgacagg catgtcctaa cgtctgaaaa tgactgggac
     4861 tgatgcgaat cagcggctct cccaccaata ataccttggt cataggggta tcctttctat
     4921 agctgcagat aagacttatt gctgaaggac ttctcttagg tagtcgacaa ggtctgatgg
     4981 ctcggcatta gcaaagaaat aatgctggaa gtgctctcca gaaatggttt ccttcaagaa
     5041 atcttgatca atctccttta acacctccaa caaagaacga taagtcacag ccttcaattc
     5101 gctcaaaatt ctagcgttac gttgctctgg gatggcccgc tctttgggat agccgccccc
     5161 catcggctca gcaaataagc gctcaaacat cagggtcagg ttaagctctg ccccccaacc
     5221 aaagcccttt gcaaatggaa tagacaaggc attgccacca ttaatctgag caaaaaggta
     5281 ggcttctgtt ggctcactag caaagccaca ggtcacacct ggaaagctat ttaaggccag
     5341 catagcaccc acaccagtcc cacagcccgt tacaacaaaa tcagctgcct tacttgtcaa
     5401 taaaatagaa gctagtagcc cgttttgcac ataggtcagc tgactttcgc cctccttgcc
     5461 atacatacca tagttaaaga cctcatagcc atgcttatta gtaacagaga ctaaggtctc
     5521 gtaaataata ctgtttttag ctgcttgact gttttcatta attaatgcaa ttttcatctt
     5581 ctgtaatctc ctttgatgct tttttgtttc tttacggttg tttgccaatg taagctaaaa
     5641 tgcctccatc aacataaagg atatgcccat tgacaaagtt actcgcctca ctagccaaaa
     5701 atatagctgg accagccaga tctgctggtg ttccccaacg cgctgccgga gtcttagcaa
     5761 taataaactg atcaaagggg tgacggctgc catcagcctg acgctctctt aaaggtgctg
     5821 tctgaggcgt tgcaatatag ccaggcccaa tgccattgca ctggatattg gcttctccaa
     5881 attctgaagc gatgtttttg gttaacatct taagaccacc cttagctgcc gcataagcac
     5941 taaccgtttc acgaccaagc tcactcatca tcgaacagat attgatgatt ttcccatgcc
     6001 cttttttaat cattgatggc agaactgcct ttgaaacaat aaatggcgca ttcaggtcta
     6061 tatctaccac ctgacgaaaa tccttagccg tcatctcaag catcggtgtc cgtttaatga
     6121 tacctgcatt attcacaaga atatcaataa taccaacctc tttttcaatc tgagccacca
     6181 tctcttgaat ccctacttca tcagtgacat cacaaacata gccatgagct ttaatgccaa
     6241 actctcgata agctgctaat ccttgatcca ctaaatcctg cttgatgtca ttaaagacga
     6301 tctttgctcc agccatggca taggccttag caatctcaaa gccaatccca tacgaggctc
     6361 ccgttatcaa ggcaattttg ccctctaaag aaaagaaatg ttccattgtt ttacctctca
     6421 atctcaatat ttaagtaaac ctgtttatca aaactatagc aagactaatc cattttgtca
     6481 atcattttag taaaaacaca aaaaagagct aaagtttttc ttattgtcat tatcgaggaa
     6541 ggcttcttag ctatattttt cttgctctta ctcgctttac ttcctataag gatcccaaaa
     6601 attaggccat attgatcgct tattttgata aaataacaaa aaagtgttga caaacatttt
     6661 tgaaagcgct ataatttttc tgagtaaacc ggtaaactaa aaaggagctt attcatgatt
     6721 tctattattg ttattggtca tgggcatttt gccagtggta ttgtctcgtc tttagagtta
     6781 attgcaggca agcaagaggg cataactgct attgatttta ctgctgagat gaccgctgct
     6841 gatgtgcatg agcgcctatc agtagtctta cagtcaaaga ctcaggcact tatgctttgt
     6901 gacttattag gcggcacccc atttaaggta gcagctacct tgatggagga gctttctgag
     6961 agcacacttg atgtcctgtc tggactcaat ctagccatgc taatagaagc agtctttgct
     7021 aggcaagagc agcttgatct agaacaaatt gtcgctaagc tattaaccac agccaaggaa
     7081 gggatcagta attggaaatc cctctctggt gaggctgatg aagcagacct tgatgaagga
     7141 gggatttaat gactagacag atcaaagagg ttacccttga gcctctcata caagcagagg
     7201 tctatagcca gcagccatat ctaacaaaag ctgatattga ggcagctatt ttattagccc
     7261 ttaagcaaat ccgattaaac atggattatt ttggtactga tttccctagg ccagccacta
     7321 aggacaattg ctacccaatt atggataata ccgagtggac caatggcttt tggaccggct
     7381 gcctatggct ggcctacgaa tacactggta atgacactat caagtcacta gcacaggcaa
     7441 atgacctgtc cttcttagaa cgcgtcacca aagacattga gcttgaccat catgatttag
     7501 gatttcttta ttcaccctct tgcatggctg agtggaagct tttaaaaaca cctgaagcca
     7561 gacaggcagc cttaaaggca gcagataaat tgattgagcg ctatcaggaa aaaggcggct
     7621 ttattcaagc ctggggacaa ctcgggaaag cagaagatta ccgcttaatt attgattgtc
     7681 ttttaaatat ccagctactc ttttttgcca gtcaagaaac aggagatgac aggtatcgtc
     7741 aaatggctat caatcacttt tatgcctcag ccaacaatgt gattcgtgat gacgcctctg
     7801 cttatcatac cttctacttt gaccctgaaa caggtgatcc aatcaaagga gttacacgcc
     7861 aaggctacag tgatgactcc gcctgggcca gaggacaagc ttggggaatc tatggaattc
     7921 ccttgaccta tcgcttcttg aaggatccac agctaattgc cttatttaaa ggaatgacgc
     7981 actatttcct caatcgcttg cccaaggatc aggtatccta ttgggatttg atctttgaag
     8041 atggcagtgg tcagtctaag gacagctccg caactgctat tgctgtttgt ggtattcacg
     8101 agatgttaaa acatttacca gagaatgatc ctgacaagaa agcttatcaa gctgccatgc
     8161 actgtatgct cagatcatta attgatagct atgccaacaa ggacatcaag cctggtgctc
     8221 cacttttacg tcatggcgtt tactcttggc actctggcaa gggcgttgat gagggaaata
     8281 tctggggaga ttactactat ttagaagccc tgctgcgctt ttacaaggac tggacccctt
     8341 attggtaggc tgatagcatt tagcctacaa agactattgt taaaggagat attatgacac
     8401 caccaaacat tatcatgacc agagttgatg agcgtttgat tcatggtcaa ggccagctat
     8461 ggatcaaatt tttaaattgc aacactgtca ttgtggctaa tgatgccgtt gctgaagaca
     8521 aaatccaaca gtctctgatg aaacctgtcg ttccatcaag cattgccatg cgcttttttt
     8581 ccattcaaaa ggtgattgac gtgattcaca aagcaagccc tgctcagaca atctttattg
     8641 ttgttaagga tttagaagac atcaagcgct tggttgaagg aggggtgccc attaaagagg
     8701 tcaatcttgg aaacattcat aaaacagacg ataaaatcgc cattacccaa ttcatttcgc
     8761 taggcgacaa ggacaaggct attattcgga cattgactca cgatcatcat attgtcttta
     8821 acactaaaac aactccagct ggcaatggtg cctctgaggt taatatttta gattatattt
     8881 aagaaaggaa attgatatgg atatcaattt gttacaagca cttttaatcg gtctttggac
     8941 agccttttgt ttcagcggaa tgttacttgg tatctacacc aatcgctgta tcattctgtc
     9001 ttttggtgtc ggcattatct tgggggactt gccaacagca cttagcatgg gagctatatc
     9061 tgaattagct tatatgggat ttggtgtcgg tgctggtggt actgtgccac ccaacccaat
     9121 cggacctggt atctttggta ccttgatggc tattaccagt gctggtaaag ttactccgga
     9181 agctgcctta gctctttcga caccaattgc cgttgctatt caatttcttc aaacctttac
     9241 ctatacagct tttgctggtg ctcctgaaac agctaaaaaa cagcttcaaa aagggaatat
     9301 taaaggcttt acatttgccg ccaatggtac catctgggct tttgctgtga ttggcttagg
     9361 acttggttta ttaggcgcct tgtcaatgga tactttactt catttggttg attatatccc
     9421 acctgtcctc ctaaatggat taaccgttgc tggtaaaatg cttcctgcta tcggttttgc
     9481 tatgattcta tctgttatgg ctaaaaaaga gctgattcct tttgtcttaa ttggttatgt
     9541 ctgtgcagct tacctgcaaa ttccaaccat cggtattgcc atcataggca ttatcttcgc
     9601 cctaaatgaa tactacaaca aaccaaagca tgcaacaaca gctgaacaag gaggtcaaca
     9661 agatgactgg atctaataag ctcacaaagc gtgattatct gaaaactgct cttagagcct
     9721 ttttcctgca aaatggcttt aactatagca attatcaagg aataggctat gccaatgtcg
     9781 tttacccagc cctaaaaaag cattttggca atgacaaaac aggcctttac aaagcactag
     9841 agaacaattg tgcattttac aatacaaacc ctcatttcct accttttatc accagcctac
     9901 acctggtcat gctagaaaat aatcggcctg aagaagaaac ccgcaatatc aagatggcac
     9961 tcatgggacc tctagcaggc atcggggata cccttacgca attttgttta gcaccactct
    10021 tttcgaccat tgctgcttcc ttagcaagtg acggcctgat tttggggcca attctctttt
    10081 tcctagccat gaatattatt ctaacagcta ttaaaattgg ctctggactc tatggctaca
    10141 aggtggggac aagctttatt gataaattaa gcgaacaaat ggcaattgta tctcgcatgg
    10201 caaatattgt cggagttaca gtgattgctg gtctagctgc tacttctgtt aagatatctg
    10261 ttcccatcac atttgcagca ggcaaggtcg acgctgcaaa tgcagcccaa aaatttgtga
    10321 ccattcaggg aatgctggat aagattgcac cagctcttct gccagccctc ttcactctct
    10381 tgatgtatta cctcattaaa acgaaaaaat ggacaaccta taaattagtt attctaacag
    10441 ttattattgg tattgttggc agctggttag gggtgttagc ctagcagtct tagagattct
    10501 gttaatcagt attggagggt ctccattagc gatgagcagg tctcttttct attgggcaaa
    10561 gctaagcatt gacaccatca actctcgtag cctcagtcag gtcttttgcc ctgtagagcc
    10621 tttaagcaca agcctttact gctagctgtg atgaaggcgt cctccttcta ctggcttctg
    10681 gcacaattaa tcctttatat ctctacaagc acatgattta gcggctgatt gcgcgccaat
    10741 cttacagaag gtcgcaactt aagaaagagt aggatcattt ttgacctctt caaaggtcat
    10801 attcttggac tgaaatatta aaacaattac cattccatat gttataataa aactactaat
    10861 gatgacaaaa aggggtctat gcaatgcagc gcaaagtaac catcaatgat attgctgact
    10921 tagctaaaac ttcaaaaaca actgtttctt tctacctcaa cggtcgattt gataaaatgt
    10981 ctcaggagac aaaaagccgg atcaaggagg ctattgaagc caccaactac aagcctagca
    11041 ttgcagctcg cagtctcaat gccaaggcta ccaaattgat cggtgtggtt atcggtgaca
    11101 tcaccaatag cttttccaac cagattgtca aaggtattga aagcaaggcg caagaatttg
    11161 gttatcagat tatcatcggc aacagcaact atgatccttc acgtgaggac gaattgattg
    11221 aaaaaatgct taacctaggt gtagatggtt ttatcattca accaacctct aactttagaa
    11281 agtattcacg catcatcgaa gtgaaaaaaa agcgcatggt tttctttgac agtcagctct
    11341 atgagcatcg tacaaactgg gtcaagacca acaattatga cgctgtttat gacaccattc
    11401 agcaatgcat caccaaaggc tatcaaagct ttatcatggt tactggcaat cctaatttgc
    11461 tgagcacacg catcgagcgt gcctctggtt ttattgatgt tttagaggct aaccagctcc
    11521 agtatcgtca aatgatcatc gatgaaaacc aaaccagctc tcaagaaatt gctcagtttc
    11581 tacaaggcgc atttgataag gaacgtcaca atctggtatt tgtcccaaac tgctgggctc
    11641 tgcctaaggt ttttactgcc atgaaggcac taaaggtatc attgcccgaa actggtctag
    11701 ttggctttga taacatcgaa tggactcgct tgtcatcacc aagtattacc actattatcc
    11761 agcctgctta cgaagaaggg gagcaagcaa ccagcatttt gattgatgat atcgaagggc
    11821 atagcaagga agccaagcaa caaatttttg attgtcaggt taattggcaa gaatcaacct
    11881 tctaacagga ttttttcgcc ttctagacct taaaaaatca gccattctaa taacgatgac
    11941 aaagtaacac gaggcttaac gcttgtttgc tagcatcaga aaaaacacat aaatcagcct
    12001 gaactacccg gttgatgaaa caataaacca ttaagcaacg gtcttattcc tcataccaag
    12061 aggagcaagg ccgttttgac gtttttgaca atggtcgtta ttgtaaacgt aacggtagtg
    12121 tattactgac aggctcttca aaaaagctgt cgtccttagg tcatacgagg ccttctttta
    12181 caagcgactg ctacttcttc actactagtg tgatctttta gccaatttct gagaacatca
    12241 tcagtaaaat ctcgcacctg ccaataatgg caagcaagct tttttgacca gcaagttaat
    12301 catgtatcac ttgtgacttc aactcttaac tgtttgtcct ttcaagtcta ctataagag
//
LOCUS       DARYLJ010000052        12208 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYLJ010000052 DARYLJ010000000
VERSION     DARYLJ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12208
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            205..942
                     /locus_tag="TU746_001636"
     CDS             205..942
                     /locus_tag="TU746_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL0891954.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            981..1481
                     /locus_tag="TU746_001637"
     CDS             981..1481
                     /locus_tag="TU746_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0891955.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            1500..2189
                     /locus_tag="TU746_001638"
     CDS             1500..2189
                     /locus_tag="TU746_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL0891956.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            2583..2825
                     /locus_tag="TU746_001639"
     CDS             2583..2825
                     /locus_tag="TU746_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL0891957.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            3005..3799
                     /gene="racE"
                     /locus_tag="TU746_001640"
     CDS             3005..3799
                     /gene="racE"
                     /locus_tag="TU746_001640"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL0891958.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            3796..4785
                     /locus_tag="TU746_001641"
     CDS             3796..4785
                     /locus_tag="TU746_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL0891959.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            4761..5282
                     /locus_tag="TU746_001642"
     CDS             4761..5282
                     /locus_tag="TU746_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL0891960.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            5279..5740
                     /locus_tag="TU746_001643"
     CDS             5279..5740
                     /locus_tag="TU746_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL0891961.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            5737..6483
                     /gene="xerD"
                     /locus_tag="TU746_001644"
     CDS             5737..6483
                     /gene="xerD"
                     /locus_tag="TU746_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL0891962.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            6483..7190
                     /locus_tag="TU746_001645"
     CDS             6483..7190
                     /locus_tag="TU746_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL0891963.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            7187..7726
                     /locus_tag="TU746_001646"
     CDS             7187..7726
                     /locus_tag="TU746_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL0891964.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            7963..8685
                     /locus_tag="TU746_001647"
     CDS             7963..8685
                     /locus_tag="TU746_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0891965.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            8682..8960
                     /gene="yidD"
                     /locus_tag="TU746_001648"
     CDS             8682..8960
                     /gene="yidD"
                     /locus_tag="TU746_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL0891966.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            9119..9667
                     /locus_tag="TU746_001649"
     CDS             9119..9667
                     /locus_tag="TU746_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL0891967.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
     gene            10046..10477
                     /locus_tag="TU746_001650"
     CDS             10046..10477
                     /locus_tag="TU746_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891968.1"
                     /translation="MVVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            10692..11105
                     /locus_tag="TU746_001651"
     CDS             10692..11105
                     /locus_tag="TU746_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891969.1"
                     /translation="MTVKKKVIILLGMVAILVMGGIFMFSYNQNQAKMLERQFNHEQK
                     RIVLYLLNHYSGINEIEFNDIENNSTTGSKNVLLTINNKIKMEVTFFNLNDDTDNYVI
                     SWNGKLSLIDKNPITHLSSIDKIKVKYWSNNDSNR"
     gene            11089..11343
                     /locus_tag="TU746_001652"
     CDS             11089..11343
                     /locus_tag="TU746_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891970.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            11359..11760
                     /locus_tag="TU746_001653"
     CDS             11359..11760
                     /locus_tag="TU746_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891971.1"
                     /translation="MMKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQE
                     RAAIYLSNTYENIHKIKIIGIDKNLKTGSMNIATIVNSKYYISVTFMGGEIYTGVEQA
                     SKDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            11763..>12208
                     /locus_tag="TU746_001654"
     CDS             11763..>12208
                     /locus_tag="TU746_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891972.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
BASE COUNT         3668 a         2198 c         2801 g         3541 t
ORIGIN      
        1 actgcaagtg ggctatctgc tgaggtaaac aataggtctt agtgcagcaa ggctatgttt
       61 atggttagct ctccttcttg tcttctaaaa aggaaagcta atgggcttac gacacctgat
      121 aaggggagaa agctcctttt aggctgatag ccttctgatg gtttttatgc aaaagagtga
      181 acaattttgt gatataataa gaccatgatt atcacatcaa aagcaaacca tttgattaag
      241 caggctaaga aattactgca aaaaaagcat cgcaagcact cttacttgat tgagggctgg
      301 cacctatttg aggaggctca gagatctggg caggaattga tacatatttt tgttctggag
      361 gaaatggcag agcgcttatc aggctttgat caggttgtca tcgtcagtcc agagattcta
      421 aaggagctga cgagctctcc caatccacag ggcattattg ctgaggttaa gctttgtcaa
      481 caggccttac cgactagcta tgctggaaaa tatttgattt tagaggacat tcaggatcca
      541 ggcaatctag ggacaatcat tagaacagcg gacgcagcaa agtttgatgg ggtgtttttg
      601 tctgagaagt ctgcggatgt ctacaatcaa aaaactctac gctccatgca gggcagtcat
      661 tttcacctgc cgatttggcg aacggatatt tatcaggtca gtcaggtgat gcagcagcaa
      721 aaaataccag tgctagcaac gaccttgtct caggattcga ttgattacaa ggacctctca
      781 gctaggagca gccttgccct tgttttagga aatgaaggtc agggcattag tcctgagatg
      841 gcagctttgg ctgatcagct gattcatatt agcatgcctg gacaagctga aagcttaaat
      901 gttgcagttg cagcaggaat cctcattttc agcctaattt aagctagtat ggtataataa
      961 tgatgtgagg tgattagtgt atgcattata cagaagatac agaatacatg gagcatgttg
     1021 gtcatttgat tgctcaccct cgctttcaaa ggcttggaga tattgttcag catcaccatt
     1081 ctactcgctt agagcactct gtcaatgttt cttattctag ctataggctg gcaaagaggc
     1141 ttggcttaga cgccaagagt accgcacgag gtggcttgct acacgatttc ttttattatg
     1201 attggcgagt aaccaagttt aacaagggac acgcttgggt gcaccctaga attgctgttc
     1261 gaaatgctaa aaaattaaca gcactcaaca aaaaagaaga ggatattatc ctaaagcata
     1321 tgtggggagc tactattgct tttcctcgct ataaggaaag ctatattgtt acctttgttg
     1381 ataaatattg ggcggtcaag gaggccatga cgccgctgcg tcaaaaatgg acgaaccgtc
     1441 gcttcctgcg tcgaaagacg cttcaaagtc acaatcatta agtaaaaaaa ggagttatga
     1501 tgaacgataa tgttatttac acacagtctg acgcaggctt gagccatttt tttgccaagg
     1561 tctatagcct ggttggtatg ggagttgggc tttctgcctt tgtttcttat ttgatgctgt
     1621 ttccatttag gcaaaattta gtctcgattg ttcttgatca tcctatggtc tattatgggg
     1681 cggctattgt tgagcttgta ctggtttttg ttgctagtgg tgctgcacgt cgcaatacac
     1741 cagcagcttt acccttattt cttgtctatt cagccttaaa tggctttacc ttgagcttca
     1801 ttattgcagc ttatgcgcaa acaacggtgc tacaggcctt tatctcatcg gcagctgttt
     1861 tctttgctat gtcactgctt ggtgttaagg ttaagcgtga tctgtcaggt attcgaaagg
     1921 ccatgtttgc agccttgatt gggattatcg tggctagtct ggtaaatctc tttatcggta
     1981 gtgacctgat gagctatgtg atcagcctta tttcagtgtt gatcttttct ggcttgattg
     2041 cttcagacaa tcagatgatc aagcaggtct accaagcctc taacggtcag gttggtgacg
     2101 gctgggctgt cgctatggct cttagcttat acctagactt tatcaacctc tttatcagtc
     2161 tacttcgtct cttgggaaga aatgactaat agctatttta agcgcagctg ctgattgtca
     2221 cttaatcgct attacgagaa atcagcgaag ctgcaggtgt taccttttgt tagaaaagag
     2281 tggctgctgc tagtaagaaa gtagctgcta ggagagcctg atgagcgtga ctgtcaagga
     2341 aggccagtta ctattgctac catctaggga aggtaccaaa aaaagtcaag aagcgggccc
     2401 aagggctcgt ttttgtttgc ttgatttgtg gtaaagtgct tcaaaccaag cctatatcta
     2461 gtctgatagc tcttatcagc tgacaacatc atatttacaa tgcctgttgg tgtagatttg
     2521 taaagcatgc tcttttttgg tataatgaga ggaacaaaaa atcgaggaga atatctatca
     2581 atatgtctac agctatctgg atattattaa tcattgttgc tcttacagcc ggtctttttg
     2641 gtgggatttt tattgcccgc aagcaaattg aaaaggaaat tggagagcac ccacgattaa
     2701 cgcctgaggc cattcgtgaa atgatgagtc aaatgggtca aaaaccaagt gaagcgaaaa
     2761 ttcaacaaac ttaccgcaac attgtcaagc aatcaaaagc cgcaatgact aagggtaaaa
     2821 aataggttac ggattagaaa tcgtggtttc taagcaatag ctaagagtga acagtctttg
     2881 atgttaaaag cttgtttaga gcttgcattg tcagttagag gtgtcaactg ttcaggggtt
     2941 aacaatagac tcagttggct cttaccagct gagtttttta tgcttcaatg aggaaataat
     3001 cgttatggac aatagaccaa ttggtttttt agattctggt gtaggaggct taactgttgt
     3061 tagtgagctg atgcgtcagc ttccccatga aaaaatcatt tatattggtg attcagcaag
     3121 agctccttat ggtcctagac ctgctgaaca aatcagagaa tatacctggg agttggttcg
     3181 ttttttatta acgaaacatg tcaagatgat tgtctttgct tgtaacactg caacagctgt
     3241 tgcttgggag gaggtcaagg aggctttgga tattcctgtt ttgggcgtta tcctgccggg
     3301 cgctagcgca gctatcaagg ctactagtgg aggaaaggtt ggtgttattg gcacatcaat
     3361 gactatttct tcaggcattt accaggaaaa gatccagttg ctggctccca ctgttcaggt
     3421 aactagccta gcctgtccta gatttgttcc tattgtggag tccaatgaga taagctcaag
     3481 tgtggccaag aaaattgtct atgaaacctt ggctccctta gttggaaaga tagataccct
     3541 tgttttgggc tgcacccatt atcctcttct taggacgatt atccaaaatg tgctgggacc
     3601 acaggttaaa ttgattgata gtggggcaga gtgtgtgcgt gatatttctg ttcttttaaa
     3661 ttattttgag attaatggca gtcgagatga tgaacatagg cgtcatcatt tttacactac
     3721 agccggctca gacagctttc aagcaattgc ctcagcctgg ctaaatcaaa cgatagatgt
     3781 ggagcatgtg accttatgag tgataacatt tatgaataca aggataaaga caattggttt
     3841 attggcaaga tgacaggcca taatttaatg gctggctggg gggttaacca tgagcttatt
     3901 gccaaaatag acgatatgtt aggtgcgatt gctggtgatg tggattggga aagtccggtc
     3961 ggttatgatg tgactgttat tcgttacgcc tccccttttg ccttgattag ctttgttgtt
     4021 ggcatgatca atcagaaagc caatcgagcc cttaaggttg ttcggcactc aggtgcgatt
     4081 ttagtgaccg aaaacgagcg attgcttgct gtgcatatgc cagatgatgg cgtccctgtg
     4141 gctgacttct ttggtcaaca ggcagatggc tttggggata cgattttgat tgcgactcga
     4201 aatgaaggca agaccaagga atttcgccgg ctttttggtg atatgggata tcgcgttgaa
     4261 aatctcaatg attacccaga gcttccagat gtggcagaaa ccggggtcac ctttgaggaa
     4321 aatgcccgcc taaaagcaga aaccatttca aggcttactg gaaagatggt tctggcagat
     4381 gattcagggc tcaaggtgga tattttaggt ggcttacctg gggtctggtc agctcgtttt
     4441 tcgggccctg atgctactga tgagactaat aatgctaagc tattgcatga gctggcaatg
     4501 gtatttgatc aaaaggatcg ctctgctcaa tttcatacga ccttggtggt tgctgcacct
     4561 ggtaaagaca gcttggttgt cgaggctgat tggcatggct atattgcaac caagccaaaa
     4621 ggcgagcatg gctttggcta tgatcccttg tttatcgttg gggagactgg acgtcatgca
     4681 gcagagctag ctgctgatga aaaaaacaag ctgtctcata ggggacaggc ggtcaagagg
     4741 ttaatggagg tatttccagc atggcaagca aaacaatcat tgtgatgagc gattcgcatg
     4801 gcgatcgtga ggttgtggca gctattaaag gccgttacct tggaaaggtt gatgccattt
     4861 tccataatgg cgattctgag ctagaaagct cagatcctat ttgggagggg attcatgttg
     4921 tggcaggcaa ctgtgaccat gatagcggct ataaggatag cctagtcacc tcctttgatg
     4981 gcttgactat tgctcaaaca catgggcatt tgtatcatat taactttact tgggataggc
     5041 tagattattt tgctcaggag actggagcgg atatttgttt gtatgggcac ttgcacagac
     5101 ctgctgcttg gcaattgggc aagactgtct ttatcaatcc tggctcggtc gctcagccgc
     5161 gtggtgaggt gaatgaaaag ctgtacgcgc gtgttgaatg gacagcagct tgcattaggg
     5221 tggattactt tacctgtcag cataagtctt acccatcact ttctaaggaa tttaaacgat
     5281 gatagcaaaa gaatttgaag cctttttaat cagtcatttg gatagctacc tgattccagc
     5341 agaggagcta gccattttta tcaacacgca taatgctgat catgtcatgc tcttattggt
     5401 tagcaatggt ttttcacgag ttcctgtcat taccaaggaa aagcaatatg tcggaacgat
     5461 cagcatttct gatataatga cctatcaagc caaaaggcag ctaacagact gggagatgac
     5521 gcaaactaat attggcgaca tggtcaatac aaagattgag accatcaata ttacctctag
     5581 cttgactgaa atcatgcata aattggttga ttttcccttt ttaccagttg ttaatgatga
     5641 caatcgattt atcggtatta ttacgcgtaa gtccattttg aaggcggtta atagcctttt
     5701 gcatgacttc actgatgaat acacaatcac aaaaaaatga tagcatttat tgaacccttt
     5761 ctagcaagca aatctcttgc taataacagc cagcaatcct atcgctatga tttaaggcag
     5821 ttttgccagc aggtcggaca gcgtattaat cctgaaaccc tagccctcta tcagcaaagc
     5881 ttgtctggcc ttacggtagc agctaaaaag cgcaagcttt caacggtcaa tcagtttttg
     5941 tactatttgt accagcagaa ggctttgaca gactatttta aaatggacga taggatagaa
     6001 gcctcttttt ctttgaagcc ccagctgaca aggcttgaca ccagcgcttt ttatgctgaa
     6061 acagccttcc taaaagggca gctcattgcg ctgctgattc tggagctggg cttgacgcca
     6121 agtgagatag cagggcttcg tcttgctgat tttgacctgg gtcttcaggt gctaaggttg
     6181 caatctcaca gaggcattcg tgtgatgacc ttatcaaagg ccttgctgcc atttttggaa
     6241 aaggcaacag aagctcagca gctctacctc tttgatcatg acgccaagcc cttttcaagg
     6301 caatggtttt ttaaccagct cagagatttt ttagagagca ttggctgtgc ggagctttca
     6361 gcccagagtc tgagagagca attcatttta aatgaaaaag cagccggtaa atccatcatt
     6421 gaggtggctc agctgctggg gctaaaaagc ccgatcacct tagaaaaata ttataagatg
     6481 taatggatat aaaagtaaaa gattttgaag gtcctcttga tttactcttg cacctagtgt
     6541 caaagtatga ggttgatgtt taccaggtgc ctattgtgga ggtcattgaa caatacttgg
     6601 cctatattga gaccctgcag gcgatgcgct tggagcttgc tggagagtac atgctgatgg
     6661 ctagtcagct gatgctcatc aaaagcagac gactgctgcc aaagctggta gacaaggagc
     6721 ctgatgagga ggatcttgag caagagcttt tgggtaagat tgaagaatat agtcgtttca
     6781 aggctctgag tcaggagttg gccagccagc atgacaagag ggctctgctt ttttccaagc
     6841 caaagcagga gcttatcttt gagcaggccg tcctacaaaa ggataaaaca gtcatggatt
     6901 tgtttttagc tttttcacag ttaatggctg caaagcaaga ggcctttaaa tataaccata
     6961 cggttattga gcgagatgat tatcgtattg aggatatgat ggagcttatt gaagctaggc
     7021 ttgagctaga gcaggagctt actttgacgg atttattgaa gcattgtgat catctcaatg
     7081 aggccattac cttgttttta gcaagcctag aattaatcaa acggcagctt gttggtattg
     7141 agcagacatc acattttggc cagattgttt tgcgaaagga gatccaatga cctatttatc
     7201 tcagctggag gccttgctgt ttgtcgcagg agaagaagga ctaagcctac gtcagttggc
     7261 cagcctatta gagttaacac cgacagcctt acagcagcag ctcgacaagc tttctcagaa
     7321 atacaaagag gataaggaat ctggcctgtg cttgattgag tcctctagga cctataagtt
     7381 agtcaccaaa gagtgtctgg ctcccttgct taaagactat gctaaggctc caatcaacca
     7441 aaccttgtca cgagcaagcc tggaggtttt gtcaattgtt gcctataagc agccgattac
     7501 tcggattgaa attgacgaga ttcgtggtgt caattcaagt ggtgccctta gtaaattagt
     7561 ggcctttggt ttggttcaag aggctggcaa aaaggaagtg attggtcgac caaatcttta
     7621 tgcaacaaca gattactttc ttgattatat gggtatcaat catttagaag agctggttga
     7681 tatttcttct attgctgttg aagagcaaga gacaaccctg ttttaaaggc aaagaggagc
     7741 ttgtctcatt tgcagatagg ccttatgccc tctactagaa gagataacag tcctaacaag
     7801 gtatagtgcc tgaaaatcct attgtcgtta tggacagcgg tctttttagg catgctatta
     7861 ataagagtag acctgtttaa gctagtgagc ttttacccat aggagagtga ctggtctgtt
     7921 ggagctatca tcagatttcc taataagaaa gagagaagga taatgagaat taacaaatac
     7981 atcgcccatg caggccttgc tagccgtcgt aaggctgaag agctgatcaa gcgagggctg
     8041 gtgaccctaa atggtcaggt gataacagat ttagcaacta ctgttaaatc aggcgacctt
     8101 gttgaggtag aggggattcc tatttacaat gaagagaagg tttattatct cctcaacaag
     8161 cctcgtggtg tcatctcaag cgtttcagat gataaggggc gtcagacagt gattgatttg
     8221 ctgccgcagg ttaaggagcg catttaccct gttggtcgct tggactggga tacctctggc
     8281 ttattaattt tgaccaatga tggtgatttt acagataaaa tgattcaccc ccgtaatgaa
     8341 atcgacaagg tttatctggc tcgtgtcaag ggagtggtaa ctaaagaaag cctgcgtccc
     8401 ttaacacgtg gtgtcgttat tgatggtaaa aaaacaaagc cggctcgtta ccgcattatt
     8461 cgtgttgagc ctgataaaaa tcgctctatt gttgaactaa ccattcatga gggccgtcat
     8521 catcaggtca agaaaatgtt tgaagtggtt ggacacttgg ttgataagct atcaaggaca
     8581 cagtttggca gccttgatgt cagaggccta aagcccggag aagccagaag gctgagcaaa
     8641 aaagaagtca gccagctaca tcatttagcg agcacacgaa aatgatcaaa gccctactca
     8701 ttgctcctgt cagagcctat cagaaatata tttctccctt atttcctcct tcctgtcgtt
     8761 atcagccgac ctgctcggcc tatatgatta cagctattga aaagcatggt gctaagggtg
     8821 ttttgatggg acttaccaga ctattaaggt gccacccttt tgccgctggc ggagaagacc
     8881 cggttccaga taccttttcc ttaaaaagac atttcataac gcatgaaaaa atacaggatt
     8941 ttgaccaaaa aactgattga caatagcagt taaagtgcta taatagcagt taagtattcg
     9001 ttggtttaaa tcaaacctgt tatgatttaa gttagcgagt caccgtcaac cacattgttt
     9061 gctgagcatg actccgggca gtgtggtttt tttgatgaaa agagtaagcg ggacaagcat
     9121 gaaacaagaa atcattaata gacaatatag ggaaaaagat agtcaaaacc atgtggtgct
     9181 ctttcagcca caaattccac aaaacacagg aaatattgct aggacctgtg ctgccaccaa
     9241 cacgccttta catatcatca ggcctatggg ctttccgatt gatgaccgta agatgaaaag
     9301 agcggggcta gattattggg ataagctaga cattagattt tatgatcatc tagatgaatt
     9361 tttagcacaa tgtgatggga gcttgcatgt gattagcaaa tttgctgata gggtatactc
     9421 agatgaagcc tacaatgatc gtcagtctca ttattttttg tttgggcgtg aggatactgg
     9481 tctgcctgag ccctttatgc gtcaatatgc tgatagggca ctcaggattc ctatgaatga
     9541 tgagcatgtc agaagtctca atgtctctaa tgctgtttgc atgatcgtct atgaggcact
     9601 tagacagcaa gcctttaagg gcttagagct tagccatacc tatgagcatg acaaactaaa
     9661 atcataataa gcatatcgca aaacatcagt tagattgaag aagtatccgt aggggagctt
     9721 cttcagtctt tttttattgt attctttgct tattaaccaa gcagttgaca cgaaaattcc
     9781 aatagatcgt ttaaagccaa taaaaccatt attaggcttg cattacaggc aggtatcaaa
     9841 gaaagatata gaaaaatata ccagaaaaaa atctcataaa agtgtcaaaa tagtaaaaaa
     9901 tcgccaaaaa tatgtcaata ttataccatt attatagtat aatatttata atcatattat
     9961 aatattaaaa tatctggtgt ctagctgttt ttgtaaaagc aaaaaacctg caccacctta
    10021 tgataaagca taaaggaata taagcatggt agtctaccta aagcaacaca aaaattactg
    10081 gaaattagtc agcatagcag ctttaatcat tattttagga ggaatactaa caatgaattg
    10141 gcttaatggg gatagggaca ataaaggcga gaataactac tatcaagtag agaaggattt
    10201 agcaatggaa attgttagtg agtttgaagg agtaaaagag attagctttc ttagtccagt
    10261 acaatccaaa gaaacagggt attggggaac aacagctact ataaataaaa ctaatgagat
    10321 atcttattct ttttcgatga ctttttcagg aaagcttgat gattattctt actattacga
    10381 taaatgtttt aaattagtga agcgtcacaa aaaattgaca ttaagtcaag tggatctaac
    10441 agatattgat attaaatatt ctaagggagg gaaataaatg ataactgaca aaaactataa
    10501 ctggctagct ggaaaagtat atgatgttga tgctaataaa gtaactattc ctgttagaaa
    10561 aaatacggat attcttaatc gttatgtcaa agtccttgaa gccgaagaca atcctgacaa
    10621 cggtatgcag tttacggtgt caaagagtaa taggaatgtt ctagctttaa attataaact
    10681 aaggagcttc tatgacagta aaaaagaaag tcatcatttt attaggaatg gtagcaattt
    10741 tagtaatggg aggtatattt atgtttagct ataatcagaa tcaagcgaaa atgttagaac
    10801 gacaatttaa ccatgaacaa aaacgaattg tcttgtattt gttaaatcat tatagcggaa
    10861 ttaatgagat agaatttaat gatattgaaa acaacagtac aacaggttct aagaatgtat
    10921 tgctgacaat aaataataaa attaaaatgg aagttacatt ttttaattta aatgatgata
    10981 cagataacta tgttattagt tggaatggga aattaagttt gatagacaaa aatcctataa
    11041 ctcatttaag ttcaatagat aaaataaaag taaaatattg gagtaacaat gatagtaaca
    11101 gataaaaatt ataatgatat agccgatggg gtttataagg ttgatgctgg caaagttatt
    11161 agaccttggc gaaacggtaa gacttttaaa actaacggga aagattaccg cgtcctcaaa
    11221 acagaagaca accccgacaa tggtatgcag gctattgctg tagctccgat taagggtagt
    11281 gaggtgggta agagtcatat catgattgtt tatgtaaaaa gcagctattg gctagcgtcc
    11341 tagcaataaa aggagttgat gatgaaaaag caacaaagca aacgacggaa actaattggc
    11401 atagtggctt taataacaat tttaggagga atactaacaa tgaattggtt taatgacgaa
    11461 aaactaaata gagagcgtag agaacaagag agggcagcta tttatttaag taatacatat
    11521 gaaaatatac ataaaataaa gatcatcggt atagataaaa atttaaaaac aggttctatg
    11581 aatatagcta caattgttaa tagtaagtac tatatatccg taacgtttat gggaggtgag
    11641 atttatacag gtgtagagca agcttcaaaa gacaatgagg aatttttaaa tcgtcgaaaa
    11701 aaagcagaga ataagacaac cttgagtaag gacattgaag ttatttataa ggagaaatag
    11761 tagtggttag tgataaagat tataataaac tctctgaaaa agtatatgat gttgatgcta
    11821 ataaagtaac tatttctgtt agaaaaaata cggatattct taatcgttat gtcaaaatcc
    11881 tcaaagccga agataccccc gacaatggta tgcaagctat ggctgttgta ccaataaaag
    11941 atggcaaaga ggatagaagt catatcgtca ttgcctatgc cgggacaaat agcagtgata
    12001 tacgcgatat tgacaccgat attcaatccg ttgtttttgg agatgatcaa tacctgtgta
    12061 cccatgagga gcctgattct tttaaagtgg tcaagagtca gctaagtact gctaaagcct
    12121 tttccgacta cattaggaca agctacccta acgctgccat ctcctacacc ggacactctc
    12181 tgggaggcta tctggcactc atcacagc
//
LOCUS       DARYLJ010000053        12203 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYLJ010000053 DARYLJ010000000
VERSION     DARYLJ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12203
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(81..1361)
                     /locus_tag="TU746_001655"
     CDS             complement(81..1361)
                     /locus_tag="TU746_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL0891973.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TU746_001656"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TU746_001656"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL0891974.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTSIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPVARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TU746_001657"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TU746_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL0891975.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TU746_001658"
     CDS             6342..6845
                     /locus_tag="TU746_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL0891976.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TU746_001659"
     CDS             7344..8537
                     /locus_tag="TU746_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0891977.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TU746_001660"
     CDS             complement(8736..9200)
                     /locus_tag="TU746_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891978.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TU746_001661"
     CDS             9468..10316
                     /locus_tag="TU746_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL0891979.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TU746_001662"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TU746_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL0891980.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TU746_001663"
     CDS             11592..12071
                     /locus_tag="TU746_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL0891981.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..>12203
                     /locus_tag="TU746_001664"
     CDS             12068..>12203
                     /locus_tag="TU746_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891982.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     G"
BASE COUNT         3668 a         2691 c         2355 g         3489 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcaa cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat gcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcg
//
LOCUS       DARYLJ010000054        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYLJ010000054 DARYLJ010000000
VERSION     DARYLJ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(152..433)
                     /locus_tag="TU746_001665"
     CDS             complement(152..433)
                     /locus_tag="TU746_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL0891983.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TU746_001666"
     CDS             complement(466..1233)
                     /locus_tag="TU746_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL0891984.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TU746_001667"
     CDS             1352..2092
                     /locus_tag="TU746_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL0891985.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TU746_001668"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TU746_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TU746_001669"
     CDS             3072..5315
                     /locus_tag="TU746_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL0891986.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TU746_001670"
     CDS             5428..6489
                     /locus_tag="TU746_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL0891987.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TU746_001671"
     CDS             6567..7172
                     /locus_tag="TU746_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL0891988.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TU746_001672"
     CDS             complement(7423..8637)
                     /locus_tag="TU746_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL0891989.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TU746_001673"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TU746_001673"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL0891990.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TU746_001674"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TU746_001674"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL0891991.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     DNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TU746_001675"
     CDS             10819..11535
                     /locus_tag="TU746_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0891992.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TU746_001676"
     CDS             11627..>12157
                     /locus_tag="TU746_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL0891993.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3304 a         2348 c         2831 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacgata atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYLJ010000055        12154 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYLJ010000055 DARYLJ010000000
VERSION     DARYLJ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12154
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(144..1283)
                     /locus_tag="TU746_001677"
     CDS             complement(144..1283)
                     /locus_tag="TU746_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL0891994.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMEKDTPRIRKEAQ
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSVRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMAYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
     gene            complement(1411..1677)
                     /locus_tag="TU746_001678"
     CDS             complement(1411..1677)
                     /locus_tag="TU746_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HEL0891995.1"
                     /translation="MGFLDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTE
                     LENVINKQAKKGYRLHTITTSNGGSKGFGGGDRIQATMVFEKIK"
     gene            complement(1689..2075)
                     /locus_tag="TU746_001679"
     CDS             complement(1689..2075)
                     /locus_tag="TU746_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL0891996.1"
                     /translation="MDLSLQEYVKGHGYELLFYDNRGTDKEAFVNHDCKVLGIGSYLD
                     DHEKKKAIYHEIGHKEHTNRQYELNRELCELEADRNMIHHLLKEELSYLDNVNEFNYA
                     RFMEKYKLKTITDEKMVIDEYYTLIG"
     gene            complement(2078..2428)
                     /locus_tag="TU746_001680"
     CDS             complement(2078..2428)
                     /locus_tag="TU746_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0891997.1"
                     /translation="MFPTFEKIKELCKQRGITLIQLEETLEYSRNTLYKLKTQKPNAE
                     RIAEIADYFNVSTDYLLGRTDNPAIANGTTSQKTIDFKEIAAQSMSYDGKPLTDDDID
                     LIAAVLEQRFKNRD"
     gene            2724..2969
                     /locus_tag="TU746_001681"
     CDS             2724..2969
                     /locus_tag="TU746_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891998.1"
                     /translation="MKKNIVDLQKRKEHFQWVADSLEGKENELYVERDWYDNPTLISK
                     EDAKKEVEQIRQELILLQNKSFIEYILQLLHQLFHRQ"
     gene            complement(2920..3708)
                     /locus_tag="TU746_001682"
     CDS             complement(2920..3708)
                     /locus_tag="TU746_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0891999.1"
                     /translation="MSRYSDYKYANTILKSIEERPEKYLIIHYSCESFYNLGGKSPRI
                     ASISVRQFNNAQTNNFSIHQYSEILDTPITDDTYETIEKELLTDFFTFVDRNTDKNWI
                     HWNMRDTVFGFHAIEQRFKVLGGTPIIIDDDKKIDLAYLFKKMYGGGYIDNPHIEKLL
                     ELNNLTPHRFLTGKQEADAFSSRQYHELSMSTSSKVNSFSTFLTLAINDDLKTNTPKW
                     KMRGTNLSGLLSTFQETISGKVIIGIINLIVGGIVGAIIAKYIQ"
     gene            3759..3950
                     /locus_tag="TU746_001683"
     CDS             3759..3950
                     /locus_tag="TU746_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0892000.1"
                     /translation="MPDIAVGREKVVTFLKSNNIKKSDLAAAYGLNRQEVTNILSGST
                     RGPKANQFILRVIADYSIE"
     gene            4031..4342
                     /locus_tag="TU746_001684"
     CDS             4031..4342
                     /locus_tag="TU746_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEL0892001.1"
                     /translation="MPKAELVYRPAKQSEKAEAGDYEHLCQIWEGLTVGTAKVWAAEM
                     RDHPDFKQFINNPTHRIVFIDYEGFRLFVKWKSRNRYKPKKETLAEMLENIKFEKRVG
                     A"
     gene            4344..4514
                     /locus_tag="TU746_001685"
     CDS             4344..4514
                     /locus_tag="TU746_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892002.1"
                     /translation="MNKLELFLLVTTVALAIVARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            4507..4710
                     /locus_tag="TU746_001686"
     CDS             4507..4710
                     /locus_tag="TU746_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892003.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            4707..5093
                     /locus_tag="TU746_001687"
     CDS             4707..5093
                     /locus_tag="TU746_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892004.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELLTLNDVERYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDKR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            5237..5440
                     /locus_tag="TU746_001688"
     CDS             5237..5440
                     /locus_tag="TU746_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892005.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            5528..5827
                     /locus_tag="TU746_001689"
     CDS             5528..5827
                     /locus_tag="TU746_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892006.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            5827..6984
                     /locus_tag="TU746_001690"
     CDS             5827..6984
                     /locus_tag="TU746_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL0892007.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGTLEKLIGKTTFADLLAEVIDKPQGKPVLVKNSDKRPALNSLEQAIKDFE"
     gene            6993..7556
                     /locus_tag="TU746_001691"
     CDS             6993..7556
                     /locus_tag="TU746_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL0892008.1"
                     /translation="MIMTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            7599..9521
                     /locus_tag="TU746_001692"
                     /pseudo
     CDS             7599..9521
                     /locus_tag="TU746_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
     gene            9526..11910
                     /locus_tag="TU746_001693"
     CDS             9526..11910
                     /locus_tag="TU746_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL0892009.1"
                     /translation="MKQEKLIVKSSPLQELHIATGNSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWRDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTEGS
                     TANGLVIYDEVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDITPTNKLPSSK
                     AMNAFVSDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPELHARSSHPVVYDPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYAIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELSYENKNVKSGGKQAKNWVGFKLKSEF"
BASE COUNT         3826 a         2119 c         2671 g         3538 t
ORIGIN      
        1 cttattatat ctaattcatt gcttgattga tctttatata aatcaataag tgattaaata
       61 aaacattaaa aaaccttgtc atatcaacgt ttgttgaaga tgtcaaggtt ttttcttgtg
      121 ttttggggca tttttggggc atattatagc cgatttaaga tgtcgacgac ttcatttttc
      181 atgcttttcg tgacgtgggt atagatttgt tgagtagttt tcgagtcagc atgtccaact
      241 ctatccatga tagtttttaa gggcactttg ttttctgcaa ggcgactcac cagggtatga
      301 cggaagatgt ggctggtgag ttctttttga atcggttttt ctagtctctt atttgccgct
      361 ctgatagagg tgttgagggc gttgtcttga ataggaacac catttctgga aatgaagatg
      421 tagcccatgt ccttgtaatt aggattagta tttttttcaa gagcattaat tttcagtata
      481 tcctgaataa tttctttttc acgtttggtt atcaatgttt cacgccaact ggaatttgtt
      541 ttaggggtgg ttttgatagc gtttctatag ccatttgagg tgtagtcaag agttccgtgg
      601 atttcaatga tatcattttt gatattgtct ggctgtatag ctagagcttc tccaatgcgg
      661 cagccattta agctcataaa ttctgccaga taagccattt taatcgatcc tttacgtcta
      721 tacatttcat ctaatagcct tttgagttca tctttttcta aaaacttctg ggcaacgtct
      781 tcaaagtctt tgatggtctt aacaggtttt gcgagttggg tactaataac tggattgatt
      841 gagacatact ctaaagcgat agcgtagtcg aaggtttgtt tgagcagctg ccgtgctcgt
      901 ttacgtttgt cataactacc tggtattttg tcgataatac tttgcaggta tttcgtggtt
      961 atcttggcaa tcatcacttc tggatcaatt aagtttcgca attctcttat tctaaaatca
     1021 agagagcgga cagaagttga tttgagtgat ttctgatgat gttcccacca ttcgttcatg
     1081 acatctagta ggtaggcatc ggttgtggta agacttgtta agattttaga tattttttcg
     1141 tcaagatatt tttgggcttc ttttcgtatt cgtggcgtgt ctttttccat aaggacagaa
     1201 gctctgcacc acttgccagt atacgggtgt ttgtaccgtt ctacaaaatt tacttttccg
     1261 cttttgtgtt tttctgacca cattgttttt tacctcattt tctgttaaaa taggtatagt
     1321 aaagagacct actgcgaagc aggtttttac tatactagat ttgcctcacg ctcgcaccga
     1381 ccaaaatttg agcgtagggc tttttttatt ttacttgatt ttctcaaata ccattgtagc
     1441 ttgtattcta tctccgccac caaatccttt actgccacca tttgatgtgg taatagtgtg
     1501 taggcgatat cctttttttg cttgcttatt aataacattt tcaagttcag ttaaatttcc
     1561 tgagcctgtt cctataagct tttcttttag tgtaacttgt agcacaacat attcataatt
     1621 ttcgccagaa gcagtcgaaa cagtactagc ttcttttaca ttgtccaaaa atcccatgat
     1681 aatctccttt aacctattaa agtataatat tcatcaatta ccattttttc atcggtaatt
     1741 gtttttaact tatatttttc catgaaacga gcatagttga attcatttac attgtctaaa
     1801 taagataact cttcttttag caagtgatga atcatatttc tgtctgcttc taattcacac
     1861 agttctctat ttagttcata ctgtctgttg gtatgctctt tatgaccgat ttcatgatat
     1921 attgctttct ttttttcatg atcatcaaga taagaaccaa taccaagaac tttgcagtca
     1981 tggttaacaa acgcttcttt atctgtgcca cggttatcat aaaataaaag ctcataaccg
     2041 tgacctttga catactcttg aagtgataag tccatagtta atctctattc ttgaatcttt
     2101 gttctaagac tgctgcaatg agatcaatat catcatcggt aagtggtttt ccatcataag
     2161 acattgactg agcagctatc tctttaaagt ctattgtttt ttgactagtg gtgccattag
     2221 caatagcagg attatcagtg cgaccaagca aataatctgt tgaaacattg aagtagtctg
     2281 ctatttcagc aattctttca gcgttgggtt tttgagtttt caacttatag agtgtatttc
     2341 ggctatattc taaagtttcc tctagttgaa taagtgtaat tccacgctgt ttgcacaatt
     2401 ctttgatttt ttcaaacgtc ggaaacattg atttatcaac ctttctaagg catgacaaaa
     2461 aatatttcaa ctttttgggt gaaaaatgtt gacaattcaa ccaaatgggt gtatcatatt
     2521 ttttgtaagc aagagataac taaaaaaaca actaagcaaa caactataaa acagttttgg
     2581 cgaacgagtt taagttgatt tgttaaggtt ctttaatatg ctttaattct aactttttag
     2641 gtgtgagttg tcaagtggtc atatactaaa aagttgaaaa tttagttatt tcttgtttac
     2701 aaattttaaa acaaggagga aaaatgaaaa aaaacatcgt tgatctacaa aagcgtaaag
     2761 agcattttca gtgggtcgct gatagcttag aggggaaaga aaacgaactt tacgtggaaa
     2821 gagattggta cgacaatccg actcttattt ccaaagagga tgcaaaaaaa gaagtagagc
     2881 aaatacgaca agaacttatt ctacttcaaa ataaatcatt tattgaatat attttgcaat
     2941 tattgcacca actattccac cgacaataag gttgattata ccgattatca cttttcctga
     3001 gattgtttct tgaaaagtgg aaagtaatcc agataggtta gttcctctca ttttccattt
     3061 aggggtgtta gtttttaaat catcgttgat agctaaagtg aggaatgttg aaaagctatt
     3121 gaccttgctt gatgttgaca tacttagttc atggtattgt ctcgaagaga aagcgtcagc
     3181 ttcttgttta cctgtcagaa aacgatgtgg ggttagattg ttcaattcaa gtaatttttc
     3241 aatatgcgga ttgtcaatat atcctccacc gtacatcttt ttaaacagat aggctaaatc
     3301 gatctttttg tcatcatcaa tgattattgg tgtgccgcct agaactttga atcgctgctc
     3361 aatagcatga aagccaaaga cagtatctct catattccag tgaatccaat ttttgtcggt
     3421 atttctgtca acaaatgtga agaaatctgt taacagctct ttttcgatag tttcataagt
     3481 atcatcagta attggggtat ctaatatctc ggagtactga tgaatggaaa agttgttggt
     3541 ttgggcatta ttgaattgac gaactgaaat ggaagctatt ctaggacttt taccacctag
     3601 attataaaaa ctttcgcagg agtaatggat aatcagatat ttttctggtc gttcttcaat
     3661 acttttaagg atagtattag cgtatttata atcagagtat cgagacattt ttacctcaag
     3721 tttttatttt tattatatca gaaaagaaag gagaaaatat gccagatatt gcagttggac
     3781 gagaaaaagt tgttaccttc ctaaaaagta acaatatcaa gaagagtgat ttagcagcag
     3841 cctatggtct caatcgtcaa gaggtcacta acattcttag tggctcaact agaggaccaa
     3901 aggctaacca gtttattctg cgagtgattg cagattacag cattgagtaa atgcaaaaaa
     3961 aaggaactga ttgcagtcag ccccttatca aaaattctac ttacattata tcacagattg
     4021 gaggtaagaa atgccaaaag ctgaattagt ttacagacca gctaagcaat ctgaaaaagc
     4081 agaagctggt gactatgaac acctttgcca aatctgggaa ggtttaacag tcggaacggc
     4141 caaggtttgg gcggcagaaa tgagagatca cccagatttt aaacaattta tcaataatcc
     4201 aacgcataga attgtattca ttgattacga aggtttccgt ttatttgtta aatggaaaag
     4261 tcgtaaccgc tataaaccca agaaggaaac cctggcagaa atgcttgaaa atattaaatt
     4321 cgaaaaaaga gtaggagcat aacatgaaca aattagaatt atttttatta gtaacaactg
     4381 ttgctttagc aattgttgcc aggatacaat atgaagtcat caaaaaacac aactcgccag
     4441 agaataagcg aaaaattttt agggaagtag ctttagaaaa cagcaagaaa tggagtgcag
     4501 aacgttatgt ctaaatggga attacaaaaa caactactgg aaaatgcgac agattttgag
     4561 agcacagttg aggctttact tgacttaaac gagtctggcg aaatatctga tctggaactc
     4621 ttactgaact taaaggataa attcagaagc tattccaaag aaaaaatacg tatccttaat
     4681 gaaattctca agctaggagg tgcagaatga tgacaacttt tgaaaagatt attaagaaaa
     4741 ttaatcggat tgagggggag ttagttaaac ctgaagctga aagacgagat agcttaccta
     4801 tcctatctgc tcagttgggt tctattaaac aagatttaaa attgatgctt tggattgagc
     4861 tactgacgtt aaatgacgta gagagatatg aagctcttta tcaaggaaat gattttaaat
     4921 tcagtgaaac tttcttagag cgtcaagcga cgagaaaagc cttttggaga cgattagcta
     4981 aagaaacttt caaagaagac caggataaga ggaactttgt taagttggct gagaaagaat
     5041 ttaaaggtgc aactttgtca tggcaagaat ttttgtgggg taaaaagaaa tgaatatatc
     5101 actaaaattt attgatgaaa ccctagctgg cttaaatgat attttacgtc agggggggct
     5161 cttgctccca aaaccaagcc ttagcagacg cagtttttat actaacagct ttaaaacaag
     5221 taattgagga gagaaaatga actatttaga atacgcacta gtttatcttg aacgtgagtt
     5281 agaaattatt gataacgaag ttatcgaagt tgagttgccg ggcggagatt gggagtttgt
     5341 gcctaatccc tactacgaga aaggtctaca tgatagccca cactatcgta gtcaggttgc
     5401 taaagacatt cttgatatta aaggactttt ggggaggtga ggctattgat tgcatcaaaa
     5461 aagacggctt aggaaaccgt caacaattat acacaattaa attataacac agaaagagag
     5521 aaacacaatg attgaagtaa cttttaaagc agagagcatg gcaggtgttt tcgatgctat
     5581 gcgtgaagct ctggatatgc cgaagacagt aaccaaggat gttgttgaag aaaaaccagc
     5641 tcctaaaaag aaagaagagt ctgtaacttt gacattagct gatattaaga aaatggctaa
     5701 agccaaggtt gaagaaggga agtcaaagga catcaaggaa gtcttgaaag agatgaacgt
     5761 cgcaaaagtt ggtgaacttg aagaatacca gtttgctgag tttgttgaga agttggaggc
     5821 cctctaatgc cagtagaaaa tcacgcacta ctgtctgctt ctagtgctca cagatggctt
     5881 tattgcccta tgctgccgag attagaagca gactatccta gccgcgatac cgtatacact
     5941 caagagggca caagcgccca tgagctttct gaaatcaaac tgatgtacaa gtctggtaaa
     6001 atcaccaagc gtaaatttaa cacgttaacc aaggctttta aggaaaactc agacttctac
     6061 aacgaagaga tggaagagat gacggaactt tacacagata ttgttatgga gcacctaaat
     6121 gcttatgaga acgccgaaat tgaacttgaa aaacgggttg attttagcga ctgggtgcct
     6181 ggcggttttg ggacttcgga tgttgtcatt ttagcggatg gggtcattga aattattgat
     6241 cttaagtatg gcaagggcat gcctgtgtct gctaaccaaa acccacagat ggggctgtac
     6301 gctctaggag cttatgcttc ctacgatatg gtttatgact ttgaccgtat caaaatgacc
     6361 attattcagc cacgtttaga ttcggttagt tctgttgaca tttacgtgga ggagttactc
     6421 tactgggcgg ataatgttgt cttgcctatg gccgctcaag cagacgcagg cattggtgac
     6481 tggaacctaa gtgaaaaagt attgcagtgg tctcctgtcg cagctaaatt ggtaccaaga
     6541 gcgcaagaaa attgggaatt aattgataaa tatgactatc aggagcctgt ctatttatct
     6601 gatgaagccg tcgcagagat tcttgacaaa gcctcagcta tcaagaagtg ggttgagtca
     6661 gttgaagcct atgccctgaa agaagcactc tcgggaaaag aagttccagg ctataagatt
     6721 gttgaaggta gaagtaatcg agtcatcact gataaagaca aagcaattga tattttacaa
     6781 gataacggct ttgacgatga gatttttaaa ccgaaagagc tgttagcaat gggaactctt
     6841 gaaaagttaa taggtaaaac cacttttgct gatttattag cagaagtaat tgataaacca
     6901 cagggcaaac ctgtccttgt taaaaatagc gacaagcgac ccgcattaaa tagcttagaa
     6961 caagcaatta aagattttga ataggagaaa ttataattat gacaccaaac acaactaaag
     7021 tagtaaccgg aaaagtacgc ctaagctatg tagctttact agagcctaaa gcctttgaag
     7081 gtcaagaggc taagtattca acagttatct taattccaaa aacagacaaa gtcacaatca
     7141 agaaaattaa agacgcgcag aaagctgctt atgaggctgc caaggacaat aaacttaaag
     7201 gggttaaatg ggagcgcgtt aagacaacgc ttcgtgacgg cgacgaagaa atggataccg
     7261 aagagcaccc agagtacgct ggacacgtgt tcatgtcagt gtcaagtaaa actaagccac
     7321 aaatcattga caagtataaa aaccccgttg actcagcgga tgaagtttac tctggcgtct
     7381 atgctcgcgt atcacttaat gcctatgctt acaacacagc gggaaataaa ggaatctctt
     7441 gcggattaaa caacgtccaa attgttgcta aaggagacta ccttggcggc cgttcgtcag
     7501 ctgatgcaga ttttgacgag tggaacgaag aagaggacga agacgacatt ttatagtaga
     7561 gggcctcttt agaggctcct catttttaaa ggagaggtat gagacattta aatattgata
     7621 ttgaaaccta tagttcgaat gacatcaaaa atggggttta caagtacgct gacgcagaag
     7681 attttgagat tttacttttc gcttactcta tagatggcgg agaagtagag tgccttgatt
     7741 tgacaaggca gtctctacct gaagacatca aagatatgtt atttgatgat aaagtccgaa
     7801 agcacgcctt taatgcccaa ttcgaaagag tttgtctcag tcgttacctc ggtctacctt
     7861 actatctaga tccttgccaa tggcaatgca ccatggtgct ggcccaagag ttggggctgc
     7921 cttcaagctt ggaaaagtgt gcgctgtatt taaaattagt gcaggaaaaa gatacctcgg
     7981 gtaaaaactt aatcagatac ttttccctgc cttgcaaacc aagtaaagct aacggtggga
     8041 gaactagaaa tttaccagaa cacgcccccg aaaagtggta aatgtttatt gactactgca
     8101 tccaagacgt tgttgttgag atggcaattg ccgaaaaact agagtcagtt cctgtgcacg
     8161 accgtgaatg ggactactac gcatgcgacc agagaatcaa cgacagaggc gtggcgcttg
     8221 ataaagagtt agttgcttcg gccttgtatt gcaaagatgt taagatggaa agtttgtctg
     8281 gtgaactaaa agctctaaca ggacttgata atcctaatag cagggcgcag ttgttaccgt
     8341 ggctaaaaga acacggttat tcggttaatg gtctgactaa agcggatgtt gagcaggagc
     8401 ttaagacggc cgaaggagaa cttaagagag ttttagaact taaactacaa accgctatgt
     8461 caagtctaaa aaaatatgaa gctatggaaa gagctatgtg ctcagacgga cgagttcatg
     8521 gactacttca gttttacgga gctagcagga caggaagatg ggcgggcaga gttgtccaag
     8581 tacagaactt agctaggaat tatataaagg atctagatga tgctagagag tatgttaaaa
     8641 agcgtgatat tgatgctgtg gagattttat acgatagtct taacgacact ttaaagcagc
     8701 tagtaagaac ggcactcgtg gccaaagact gctgtacctt ctacgtctct gacttctcag
     8761 cgattgaggc tagggtgatt gcgtggtttg ccggagagca gtggaggctt gacgtgtttt
     8821 cgacgcacgg aaaaatctat gaggcatccg ctagccagat gttcggaatt ccaattgagg
     8881 agattgataa ggaactacgc caaaaaggca aaatctcaga gttggcactt ggctatcaag
     8941 gaggtcctgg agcgctcaag cagatgggag ctctaaatat gggagtcaag gaagaggagc
     9001 tccaagggct agttgatgac tggcgcaggg ccaataagaa aatcgtccaa ttttggaaag
     9061 atgtgcagag agccgccatc aaagctatca aatcgagagc accaataaaa cttggaaaac
     9121 tacgatttag ataccgtaaa ggtttcctct ttataacatt gcctagcggt aggaacttag
     9181 cttatgcaag agccaaggtt gagccaggcg actatggaga caaaatcgtc tatgagggcc
     9241 aaggagataa ggcctacttc acagcgcaag agacttacgg cggtaagctt gtcgaaaata
     9301 tcgttcaggc gacggccagg gatattctag ctgaagcgct tctgaggatt gaagctgcag
     9361 gctatggtgt tgttttccac gttcatgatg aggctattat cgaaggctca ggcctgacaa
     9421 tcgaagaagt taatgatttg atggctcagg ctcctgaatg ggcggagggt cttcctttaa
     9481 atagcgaagg ctacgtaaca aagtattata tgaaggatta gatagatgaa gcaagaaaaa
     9541 ctaatagtaa agtcttctcc tctgcaagag cttcatatcg caacgggtaa ttcacgaaca
     9601 gctaagacgt ggaaaaatat tacgctaact tggcaggagc tggttgagag gttagagaaa
     9661 cctacagtca cccaagagac gtttgcggag taccagaaga tgtctcgagc agaaaaaggg
     9721 caagcaaaag acgtaggagg ttttgtcggc gggtggctaa agcagggtaa acggaaaaac
     9781 gaaaatgttc aaagtaggtc cttggttgcg cttgacgcag atagcccaag taaagatttc
     9841 ttagataggc tagacctgct tgcagactat gcatacgtac tctacagtac tcacagccac
     9901 tcaaaaaaag ctgctaagta ccgtcttatt atccctactg accgtttaat gatgcctgat
     9961 gaatatgagc cagtcgctag gtacttggct aatcaactag gcatgtcgaa ctttgatgac
    10021 acgacttatc aaagtgtgcg tttgatgttc tggccgagcc actcgagaga tgctgacttt
    10081 acgtttaaat ataacgatga ggcttttcta agtgttgatg aggtgcttga tacatacccg
    10141 gactggcgtg actcaagctt ctggccagaa agcccgacgc acgctgttaa aagacagcgt
    10201 gaagctaaaa aacaaggtga cccacttagt aaaaaagggc ttattggagc cttttgtcgt
    10261 aactatgaca ttagacaggc cattgcaacg ttcttgcccg aggtttatga agaaggaacg
    10321 actcctgata ggtacaccta cactgagggt tcaaccgcaa atggcttagt catctatgat
    10381 gaagtcttcg cttatagcca tcacgggaca gatcccgtgg gggatacgct tgtaaatgca
    10441 tacgaccttg ttcgtatcca taaattcgga gagcaagata gcgaggctaa agatattact
    10501 cctactaata agttgccatc aagtaaagcg atgaatgctt ttgtctctga cttacccgaa
    10561 attaaagact atttaatggc ggaggcttta ggcgattttg atgaagagtt accagtcgaa
    10621 gatgacagaa gctggcttga aattgatgag aggggcgaac ctgaggtcaa tagttatttg
    10681 ctagcaacgc agattattaa ggaggttccg atttattggg acggcttaga atttttacgc
    10741 tacgacgcta aaaaaggcat ctggttgcca aacgcagagg agtatttgaa gagttatatc
    10801 tcaactaaga aactcggtaa aattactaag attaggcaca ttagcgaaac cgtcgtagcg
    10861 attaaggcac aggctttctc aagcgaagtg tttactgaga gcgatcttaa caagatagtg
    10921 ctagcgaacg gagtctatga cttgagggat aacagtttta agactaagtt tgatccagaa
    10981 ttgcatgcaa ggtcaagcca tcccgttgtc tatgaccccg aggcggcctg tgaaaccttt
    11041 gagggttttc ttagggagac cgtcggagct gaaaatatag atttcatctt tgagtggttc
    11101 ggctataact tttatcgcga atatgctatc caaaaaatgc tattcatcta cggcagcggc
    11161 ggtactggta aatcaacact gattaatatt ttacgtgaaa tgataggtgc tgataattac
    11221 tcagccgtga cactgcagta cctgatgcaa gaacgctttg caaaaatcgg cttatatcga
    11281 aagactgcta acttcgatac cgatgctaaa cctcaatact tagcagatgg cgcaacactt
    11341 aaaatgttga cgggggagga tactattcac gcagaccgta agaataaaga gccgattaac
    11401 ttttacaatt atgctaagct gtcttttgcc atgaatgagc tcccacctat gcgagatttc
    11461 agcggaggac ttaaacgccg catgatgatc ctcgagatgg ataaggtttt aacgcaggaa
    11521 gttaaggcga aatacccgct agataagatt atgagcgagg tgccaggtat ctttaatagg
    11581 gcgatggagg ggcttagaaa ggccttaagt aagagagatt tcagtattag tgccagcatg
    11641 agatcaagtg tcgagaaatg ggaaaaaggc aacgatgtcg tggccatgtt ccttgaagac
    11701 gagtgtgaac ttggtgaaga cttcaaagtt cctgttaggg atgtctaccc agcctacaag
    11761 ttctattgtc aggattcagg ctacaaacct ttggcaaaaa atgcatttaa ccaccgacta
    11821 agagagttaa gttatgaaaa taaaaacgtt aaatctggag gaaagcaagc caaaaattgg
    11881 gtcggtttta agttaaaaag tgagttttag gggttacttt tttgggatta gagtttggta
    11941 accctagaaa aaagttacca agttaccggt ttttcaaact ttaaaaataa aaaatttaaa
    12001 aataattttt aaaaaatcaa aactgaattg gaaaaatcgg taacttagta actcgaccct
    12061 tagaaatggg ctcgaaaagt agccctggta gcttattggt agccctaaga aacctttcat
    12121 agcaatagct tagcccctat ggttaccaat ctac
//
LOCUS       DARYLJ010000056        11485 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYLJ010000056 DARYLJ010000000
VERSION     DARYLJ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11485
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            131..1381
                     /locus_tag="TU746_001694"
     CDS             131..1381
                     /locus_tag="TU746_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL0892010.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1490..2371
                     /gene="truB"
                     /locus_tag="TU746_001695"
     CDS             1490..2371
                     /gene="truB"
                     /locus_tag="TU746_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL0892011.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2385..3317
                     /locus_tag="TU746_001696"
     CDS             2385..3317
                     /locus_tag="TU746_001696"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL0892012.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3360..3764
                     /locus_tag="TU746_001697"
     CDS             3360..3764
                     /locus_tag="TU746_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL0892013.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3766..4044
                     /locus_tag="TU746_001698"
     CDS             3766..4044
                     /locus_tag="TU746_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL0892014.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            4034..4810
                     /locus_tag="TU746_001699"
     CDS             4034..4810
                     /locus_tag="TU746_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL0892015.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4827..6134
                     /locus_tag="TU746_001700"
     CDS             4827..6134
                     /locus_tag="TU746_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL0892016.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6272..7138
                     /locus_tag="TU746_001701"
     CDS             6272..7138
                     /locus_tag="TU746_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL0892017.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7149..8084
                     /gene="pstC"
                     /locus_tag="TU746_001702"
     CDS             7149..8084
                     /gene="pstC"
                     /locus_tag="TU746_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL0892018.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8074..8961
                     /gene="pstA"
                     /locus_tag="TU746_001703"
     CDS             8074..8961
                     /gene="pstA"
                     /locus_tag="TU746_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL0892019.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            8978..9781
                     /gene="pstB"
                     /locus_tag="TU746_001704"
     CDS             8978..9781
                     /gene="pstB"
                     /locus_tag="TU746_001704"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0892020.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9795..10553
                     /gene="pstB"
                     /locus_tag="TU746_001705"
     CDS             9795..10553
                     /gene="pstB"
                     /locus_tag="TU746_001705"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0892021.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10624..11277
                     /gene="phoU"
                     /locus_tag="TU746_001706"
     CDS             10624..11277
                     /gene="phoU"
                     /locus_tag="TU746_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL0892022.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
BASE COUNT         3385 a         2137 c         2633 g         3330 t
ORIGIN      
        1 tcccttggga cacaaggggt tagctggtct ttacttgttt ttaagtgata aagtcgggag
       61 tctggaaaaa tcattttcta ggcttttttt gctataatgg cagtgagata attgcaagaa
      121 tggagaaatc atgaaagaac taaaatgtcc tcattgccat accttattta cggtcaatga
      181 gtctgactat agtcagattt tagcacaggt acgaggtcaa gagtttgaca aggagttggc
      241 acagcgctta gaaagtgaga tgaagctgca agaagcaagg gccaataacc gcttccaaga
      301 ggtgcttact aaaaaggagc aggctattca aagcctgacc aaccgcttgg agcgtattga
      361 gcaggaacag gcctatttga ggcaacagga gctagcccaa aaggataaag agctcctaga
      421 gcttcacaat cagctagata agctagagct tgagcagcaa tcaaggctcc agtctgccct
      481 tacagttgtt gaaaaggaac gtgatcacct aaaaaatcag ctcgtgctgc aggaaaaaga
      541 aagcgaactt tctctagcct ctgtgcgcag tgattatgag gtgcagttaa aggctgtcaa
      601 tgagcaggtt gagttttaca agaattttaa agcgcagcag tcaactaaag ctattggaga
      661 gagcttagag ctgtatgccg aaaccgagtt taacaaggtt cgcagctatg cctttccaaa
      721 tgccagtttt accaaggaca atcaagtgtc tcatcgaggc tcaaagggtg attatattta
      781 ccgagagcta gacaataatg gtgttgaaat tctctcaatc atgtttgaaa tgaaaaatga
      841 ggttgacacg accaagacca agcataaaaa tagtgatttc tttaaggaat tagataagga
      901 tcgccgggaa aagaattgtg aatatgctgt tcttgttacc atgcttgaag cagacaatga
      961 ttattacaat gcaggaattg ttgatgtcag tcatgactat gacaaaatgt atgtggttcg
     1021 gcctcagctc tttattcatc tcatcggatt gctgcgtaac gctgctctta atagcttaaa
     1081 atataagcaa gaactggcgc ttgtcaggga gcagcacatt gatattacac attttgagga
     1141 ggacctagag cattttaagc atgcttttgc taaaaactac cagtctgcaa gcaataactt
     1201 taaaaaagcc gttgatgaaa ttgataagtc catcaagcgt atggaggagg tcaagcgctt
     1261 tctaacaact agcgaaaatc agctgcgttt agccaataac aagctagatg atgtctctgt
     1321 caaaaaacta accagaaata atccaaccat gcgcgataag tttcaagcaa tcaagcccta
     1381 ggattatctc agtcaggctt attgatagag gctttgttgc ttgtcaaaag ccttgtgaaa
     1441 tggttataat agataggcta atgatcaaaa caataaacga aagtaacaca tgataaacgg
     1501 aataatcaat ttaaaaaaag aagcaggcat gacatcacat gacgctgttt ttaagcttag
     1561 aaagctatta caagaaaaaa agattgggca tggagggacg cttgatcctg acgtggtcgg
     1621 tgttttgcct atagcagtgg ggaaggcaac gcgagttatt gaatacatga cagaagcagg
     1681 taaaacctat gagggagagg ttactcttgg ctattcaacg acaacagagg atgctagtgg
     1741 agagattgtt gaccaaacag tagtgccctt gagtttgact gaagcgatgg ttgatgaggc
     1801 aatgacacaa tttattggtc aaatgactca gattccaccg atgtattctg cggttaaggt
     1861 taatgggcgc aagctttatg attatgcacg agctggtgaa gcagtcgagc gccctaaaag
     1921 acaggtaacg attgaccagt ttgagcggac aagtcccttg acctttgcag gtggtctttg
     1981 ccgatttagc tttagggtga gctgtagcaa ggggacttat attaggacct tggcggttga
     2041 tctaggaaga atgcttggct atgcaagtca tatgtcttgg ctggttcgga cagcttcttc
     2101 gggtttaagt ttggatcagt cctatacctt gtcagagatt gctgagctgc tggataaaaa
     2161 ggacatgagc tttttattgc ctattgaata tggtgttagt gatttagcca gagtagtcgt
     2221 taatgactgg gagctgagag agctttcctt tggtagaaaa atcgctctat catgtgagga
     2281 aaatctgtta gcggcttttt atcaggacag cttgatcgct attttagaaa agcaagaagg
     2341 gctttacaag ccaagaaagg tttttattta gagaagattg atatatggat atacaacaca
     2401 ttaaaagcta tcaggagatt gatgaatcag ctgataccgt tttagtctta ggctactttg
     2461 atggtctgca ccgaggtcac aaggctctat ttgataaggc aaaggaaata tcacgtcagg
     2521 aaagcctaaa aatagtcacc ttgaccttcc atgagtcccc tcagctggcc tttacacgct
     2581 tttctcctga ttttttacga cacattacct atccagaaaa aaggtatgaa aaatttgctg
     2641 agtatggtgt tgataagctt tatttgcttg attttaccac gtcattttca aaactatcct
     2701 ctgatgattt cattgaccac tatattgggc gtttaagggt aaggcatatc gttgtaggct
     2761 ttgattatca ctttgggtgt gatcacgcag atagtcatta cttagctaaa cggataaaag
     2821 gaaccgttta tagcatttca gaggtcaaag aagaccagat caaaatctca tcaacacgta
     2881 tcagaagtct gattacagca ggagatgtcg ctaaggctaa tcagctgctt ggctatgagc
     2941 tttcaacaag aggaatggtt gtgcatggtg atgcgcgtgg gcgaaccatt ggttttccga
     3001 ctgccaatct tgcacctatt gataggacct atctgccagc tgatggtgtt tacgtgacag
     3061 atgtgctggt tagaggaaag cgctatcggt ctatgacgag tatcggcaag aacattacct
     3121 ttggtggtaa agagctgcga ttagaggcaa atatttttga ttttaatgag gacatttatg
     3181 gagaaactct tgaaattatt tggctagata ggattcgtga gatgaataaa tttagtgatg
     3241 ttagcacctt tatcagccaa ctaaagcagg ataaagaagc tgccataaat tggaaaaaag
     3301 atagccaagg ctattaaatt tttgtataat aaggtaagca caattaacag aggaaaagta
     3361 tgattacctt atttctatca ccaagctgta ctagctgccg taaggccaga gcctggctca
     3421 ccaagcatga cgttgacttt caagagcata atattattac cagcccactt agtcgtgagg
     3481 agctgttagc gatcctatcc tttactgaaa atggaacaga ggatattatt tcaacacgat
     3541 caaaggtttt tcaaaaattg gatattgata ttgatgagct gtctatcatg gatttgattg
     3601 atttgatcgc aaagaaccct agccttcttc gtaggccaat cattatggat agtaagcgca
     3661 tgcaaattgg ctttaatgaa gatgagatta gggcattttt gccaagggat tatcgtaagc
     3721 aagagctgcg ccaagcaacc ataaaggcag aaatcgaggg ataacatgtc agatcattat
     3781 cattacccac ttgatgtaag ctggagcact gaagagataa catcagtgct tcatttttta
     3841 aatcaggtag agttagccta tgaggctaag gtaggagcag aggagctact caaaagctat
     3901 gctgcctaca aggagattgt aagaagcaaa tcacaggaaa agcagattga ccgcgaattc
     3961 caacaagcca gtggctattc aacctatcaa gctgtcaaaa aagccagaga aattgagaaa
     4021 ggattctttt cccttggaag ataaatacgc atttgctaaa acgatcatca aagaggctgg
     4081 ccttctgatt aaggatagaa tgaaagatag cttagccatt gaaatcaaga cgcagcatga
     4141 tgatttagtg accaatgtag atcaagagac gcaggatttc ttaattgcta aaatcaaaca
     4201 ggcctatcct agtgaccata tgattgctga ggagggcggt atctgtcatg ctattacaga
     4261 tggcaaggtt tgggtgctgg atcctattga tggtacggtg aattttattg tacagaaagc
     4321 caattttgcg atcatgatgg cttattatga gaatggcgtc ggaaaattta gtctcattta
     4381 tgatgtcatg gcagatcagc ttttttcagg tggaggagat tttgctgtta ctttaaatga
     4441 tcaagtccta gcatcttatc aggataagcc gcttgatcgt agcttaattg gctgcaatgc
     4501 aggtatgctt tcaaggaacg attacaacct gcaccagttg attgatcaaa ccctaggagt
     4561 gagggtttat ggcggtgcag gcatttgcat gactaaggtg ttaaggcagc agctaatggc
     4621 ttatttctct tatattcaac cttgggatta tgcagcggca gccattatgg gcgaaagcct
     4681 tggctatgtc ctgttgacct tggagggaaa gcagccagac tttcagtcta gacagaaggt
     4741 gatgtttgtt cccaagtcta aactagccac cattcaatct ctgctgaaaa caaacgagaa
     4801 tacccaataa gattaaaatg aaaagcatgc aattaccaaa cgattttatt gaaaaatacc
     4861 aacagctgct aggttcagaa gcaaaagctt tttttgagag ctttgatcag cctgccatca
     4921 gtgcctacag gataaatccc ttaaagcacc aatcggtctg ccttgatcct cctattcctg
     4981 atacaccatg gggttactac ggcagggtat caggaaagtc tcctaaccac gtgtcaggtg
     5041 tggtgtattc ccaagagcct gctgctcaaa tggttgctca ggtggcctca cctgccaagg
     5101 gaactagagt gttggatttg gcagcagcgc caggtggcaa gtcaactcag ttacttgcct
     5161 atctagagaa tacaggactt ttagtgagta atgagatttc gaccaaacgc agcaaggcct
     5221 tagttgaaaa tatagagcgc tttggtgcta gaaatgttat tgtgacaaat gagtcagctg
     5281 acagactggc tgctgttttt ccagaatatt ttgacactat tgtctttgac gggccttgct
     5341 ctggtgaggg catgtttcgc aaggatccaa atgctgttag ctattggcac aaggattacc
     5401 cagcagcatg tgctagcctg caaagatcca ttttagcaga ggcgatacct atgctaaagc
     5461 caggtggtca gctgatttat tcgacctgca cctggtcgcc tgaagaaaat gaagaggttg
     5521 ttcgctggct actagaaagt tatgattttc ttgagctgga gcatatccct aagatcaatg
     5581 gtatggcaga ggggatcggt atgccacagg cagctagaat gtaccctcat cgctttaaag
     5641 gagagggaca gtttgttgct aagttaaagg atactagatc aacgatttcc tcttcaagct
     5701 acaaatctcc aaggtctaac ctcactcaag agcagctgag gctgtggcag gattttgaaa
     5761 aaaatcattt gaacataacc ttgtctggcc tattacaggt ctttggtgat cgtttgtact
     5821 tgttaccaga tggcttaccc tgtcttcgat cgcttaaaat agcaagaaat ggtctggaat
     5881 taggcacttt taagaaaaaa cgctttgagc cttcctatgc tctgggcttg gcattaagac
     5941 ctgaagaggt cagcttatct gttgagatta acgaagagga ctttgtcaca tacgcctcag
     6001 gaaataccat taccttacca gaatcttatg ctacagattg gtatcagctg gtcattaacg
     6061 gaaatggtct gggctttgct aaaatagttg gtcgcaccct taaaaatagc ttccctaagg
     6121 gcttacgttt ttaaggaatg gcataccatt aaatttttat aaatttaaat aaaacttctt
     6181 ccaaagcatt gttagatatg ttaatataaa gaatatgctg aagcttaatt cttcgctata
     6241 aacctttatt tttatgaata ggaatagaat aatgaaatcg aaaaagaaat tctttttgtt
     6301 aagtctttta gccttgtcgg ctttcttttt gtcagcctgc tcaagctgga ttgataaggg
     6361 agaatccata acagcggtag gctcaacagc attacagccc ttagtagaag ccgcagctga
     6421 tgagtttgga agcaataacc tcggaaaatc tgttaatgtt caaggaggcg gctctggcac
     6481 tggcttatca caggtgcagt caggtgctgt tcaggtaggc aatagtgatg tctttgcaga
     6541 agaaaaggac gggattgatg ctgctaagct tgttgatcac caggttgccg tagcaggact
     6601 tgctgtcatt gccaatccta aggtcaaggt atctaatctc acaagcaagc agctacaaaa
     6661 gattttctca ggtgaatata ccaactggaa gcaggttggt ggacaggatc ttgctatttc
     6721 agtgattaat cgagcggcaa gctcaggctc acgtgctacc tttgatagtg tcatcatgaa
     6781 gggtgttact gctaagcaaa gtcaagagca ggattctaac ggtatggtta aatcaattgt
     6841 gtctcagaca ccgggggcca tttcttactt atcctttgcc tatgtggatt cgtctgtaaa
     6901 atcattacga ttgaatggct ttaaggccaa tgccaaaaat gtagcaacca atgattggcc
     6961 catctggtcc tatgagcata tgtataccaa aggcaagcca gacggcttaa ccaaggaatt
     7021 tttggattat gtgctatcag atgaggtcca aaaaaccatt gtgacacata tgggttatat
     7081 tgctatcact gatatgaagg tcgtcaaatc ctatgatgga aaagttacag ataaataatg
     7141 ggggaattat gaaaaatcag gaattagcta agcaattagc ctcaccatca aaaaattcac
     7201 gacttgaagc atttggtcgt acgattacct ttttttgcct cgccttaatt gtttttatcg
     7261 ttgcaatgat tttacttttt gtggctcaaa agggcttgtc tacctttttt gtaaacaagg
     7321 ttaatctttt tgatttccta tttggtacag agtggcagcc tagcgttaaa aatgctgccg
     7381 gtgttcctta tcttggagct cttccgatga ttgctggatc gtttttagtc acgattttat
     7441 cagccttggt ggcaacacca tttgccattg gggcagcagt atttatgact gaaatttcac
     7501 ccaagtacgg ggcaaaacta ttacagccag cagttgaatt gcttgtaggt atcccgtcag
     7561 ttgtttatgg ctttattggc ttgcaggttg ttgttccttt tattcgttct atttttggtg
     7621 gaacaggctt tggtatccta tcaggggtct gtgtcttgtt tgtcatgatt ttaccgacgg
     7681 ttacctttat gacaacagat agtctgcgcg ctgttcctcg tcattatcgt gaggcttcta
     7741 tggctatggg ggctacacgt tggcaaacca tttggcgagt ggttttaaat gcggctcgtc
     7801 ctggtatttt tactgctgtt atttttggta tggctagagc ctttggtgag gccttagcca
     7861 ttcaaatggt tgtgggaaat tcagcagtca tgccggcttc actaaccact ccagcggcta
     7921 cattgacctc tgtattgact atgggaattg gtaatacagt tatgggaact gttcaaaata
     7981 atgtgctatg gtcattagcc cttgtcttat tgctgatgag tctagctttt aattcccttg
     8041 tcaaattaat tacgaaagag agaaagagaa attatgaacg ctaaaaaggt tgataaagta
     8101 gcaactggta gcttgtatac tattgctgga attattgtag ctattttagc ttccctaatt
     8161 ctgtttattc ttgtgcgtgg cctacctcac atcagctggt cgtttttaac agggaaatca
     8221 tcgtcctatg aagctggtgg aggtattggg attcagcttt ataattcatt tttcttgctg
     8281 gtagtaacct tgattatttc cattccccta tcaacaggtg ctggcattta tttggccgaa
     8341 tacgctaaaa aaggacctgt gacaaatgtg attagaacct gtattgaaat cctatcctca
     8401 ttgccatctg ttgtggttgg attgtttggc taccttattt ttgttgtaca gtttgaatat
     8461 ggcttttcta ttatatcagg tgcccttgct ttgacggtat ttaatcttcc gcaaatgaca
     8521 agaaacgttg aggatagctt gctgcatgtg catcatactc aaagagaggc agggctagcc
     8581 cttgggcttt cacgctggga aacggttttt catgtggtta ttccagaggc cttgccaagt
     8641 attgtgacag gtattgtttt ggcttcaggt cgtatctttg gtgaagcagc tgctcttatc
     8701 tatactgcgg gtcagtctgc cccagcgctt gattggtcaa attggaaccc tttgagcgtg
     8761 acaagcccta tttcaatttt ccgtcaatct gaaaccctag ctgttcatat ttggaaggtc
     8821 aatagtgaag ggacaatccc tgatgcaaca cttgtttctg ctggtagtgc agcggtgttg
     8881 ttgattttta tccttatttt caatctatca gctcgcttta ttggcaagcg tattcatgct
     8941 aagatgacag cagcaaaata agacattgga gagattcatg acagaatata attggaacga
     9001 acgtcatatc attacatttc cagaagaaac gattgcccta gctactaagg atctgcatgt
     9061 ttattatggt agcaaggagg caatcaaggg gattgatatg caattcgaaa aaaataaaat
     9121 tacagcccta attggaccct caggctgtgg caagtcaacc tatctgcgca gcctcaatcg
     9181 catgaatgac accattgata ttgctagagt aacaggtgaa attttgtatc aaggcattga
     9241 tgtcaatcga aaggacatga atgtgtatga aatccgtaag cacctaggaa tggtctttca
     9301 aaggccaaat ccatttgcca agtctattta taaaaacatc acctttgctc atgaaagagc
     9361 aggagtgaga gataaaaggg ttttagatga gattgtcgaa acctccctca agcaggctgc
     9421 actatgggat caggtcaagg acgatcttca taaatcagcc tttacccttt caggaggtca
     9481 gcagcagcgc ttgtgtattg ctagggctat ttcggttaag ccggatatct tgttgatgga
     9541 cgaaccagct tcagcccttg atcctattgc aaccatgcag ctagaagaaa ccatgtttga
     9601 gttgaagaag gattacacca ttattatcgt tactcataac atgcagcagg ccgctagagc
     9661 aagtgattac actgctttct tctatttggg tgacttaatt gaatacgata aaacgcgtaa
     9721 cattttccaa aacgctacct gtcagtccac aaatgattac gtctcagggc actttggtta
     9781 gaaagaagga tatgatggca gaacctattt tacaaatcag agatctttct gtttactata
     9841 ataaaaagaa aaccttaaag gacgtgtcct tagattttta cccaaatgaa atcacagcac
     9901 tcattggccc ttcagggtct gggaaatcaa cacttttgcg ttccatcaat cgcatgaatg
     9961 acctgaatcc agaggtaacc attacggggt caatcgttta taatggacat aacatttaca
    10021 gtccaagaac agacactgtt gatttgcgaa aagaaattgg tatggtcttt cagcagccca
    10081 atccctttcc aatgtctatc tatgaaaacg ttgtctatgg cttgcgccta aagggcatta
    10141 gagataaggc tgttttagat cacgctgttg aatcctctct caaaggagcc tccatctgga
    10201 gtgaggtcaa ggataggctt catgattcag ctgttggact atcaggaggt caacagcagc
    10261 gtgtctgcat agcaagggtt ctggcaacca gccctaaaat cattttgtta gatgagccaa
    10321 catcggcttt agatcccatt tcagccggca aaatcgaaga gaccctgttc tcactaaaaa
    10381 aggattatac gatggttatc gttacccgct ccatgcagca ggcctcgcgc ttgtcagacc
    10441 ggacaggctt cttcttagag ggagaccttc ttgagtttgg tcctactaag gcaatgttta
    10501 tgaaccctaa gaggaaggaa acagaagatt atatttcggg taaatttggc taagggatct
    10561 tgtttgtagt ctaggtatcc gctctgttta ggataataaa tgaatcaata gaaagaaaaa
    10621 atgatgttaa gaactaaatt tgaagaagaa ttagacaagc tacacaatca gttttactct
    10681 atgggaacag aagtcttgtc tcaaatcaat aaaaccgttc gtgcctttgt cagtcatgac
    10741 cgcgaattgg ccaaagaggt gattgaggaa gacgatacca tcaatggatt tgaaacaaaa
    10801 ttagaaaaaa agtctcttga aattatcgcc ttacagcagc ctgtttcaaa cgatttgcga
    10861 acagttatta ctgttttgaa ggcctcaagt gatattgagc gtatgggaga tcacgctgcc
    10921 tctatcgcta aagcaaccat tcgcatgaaa ggagaagagc gtatcccgat tgttgaggag
    10981 catatcaact tgatggggaa ggcagtcaag cagatggttg aagaggcgct aaatgcttat
    11041 attaatgcag atgatgccaa ggcctatgaa attgctgctt cagacgaaat cattgataat
    11101 tatttccgcg aaatccaatc tctagctgtc gaagaaattc gcaagacacc agatgccgtc
    11161 tttgctggca aggaatactt ccaggttctc atgtatttag agcgtatcgg tgactatgct
    11221 cgtaatattt gtgaatggat tgtctattta aaaactggaa aaattattga attataagaa
    11281 agtatggtat aatgggggct gggtgaactt ctcagttcct cgttttatta tagcgattaa
    11341 aaggttttag aggctggagc ttcagctgag ctgactatca gctgtcaagc ttctagacaa
    11401 aatgaaagat aacaataagc tagtcgtcta agggactaga cggcaggatt gattatatta
    11461 agaatgtgac cttgtcccat cacta
//
LOCUS       DARYLJ010000057        11425 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYLJ010000057 DARYLJ010000000
VERSION     DARYLJ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11425
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(72..2753)
                     /locus_tag="TU746_001707"
     CDS             complement(72..2753)
                     /locus_tag="TU746_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL0892023.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TU746_001708"
     CDS             complement(3101..3487)
                     /locus_tag="TU746_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL0892024.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TU746_001709"
     CDS             3568..4869
                     /locus_tag="TU746_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0892025.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSENHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TU746_001710"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TU746_001710"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL0892026.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TU746_001711"
     CDS             5903..7117
                     /locus_tag="TU746_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL0892027.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TU746_001712"
     CDS             7117..8352
                     /locus_tag="TU746_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL0892028.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TU746_001713"
     CDS             complement(8561..9319)
                     /locus_tag="TU746_001713"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL0892029.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TU746_001714"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TU746_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL0892030.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3433 a         2587 c         2262 g         3143 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgagaacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaatct ttcatgtgtc tatcgtggtc gatgatcgca gagttagctt gttaatattt
    11341 tctatctttt ttattatatt ttgttaattt tataatctat ttaactattt taaaaattta
    11401 cttatttaaa tcacaaaaca ctgtt
//
LOCUS       DARYLJ010000058        10996 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYLJ010000058 DARYLJ010000000
VERSION     DARYLJ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10996
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(32..1213)
                     /locus_tag="TU746_001715"
     CDS             complement(32..1213)
                     /locus_tag="TU746_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0892031.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TU746_001716"
     CDS             complement(1297..2532)
                     /locus_tag="TU746_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0892032.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TU746_001717"
     CDS             complement(2854..4092)
                     /locus_tag="TU746_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0892033.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TU746_001718"
     CDS             4400..6376
                     /locus_tag="TU746_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0892034.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TU746_001719"
     CDS             6440..7939
                     /locus_tag="TU746_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0892035.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TU746_001720"
     CDS             7939..8865
                     /locus_tag="TU746_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0892036.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TU746_001721"
     CDS             8874..9944
                     /locus_tag="TU746_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892037.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TU746_001722"
     CDS             9937..10860
                     /locus_tag="TU746_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892038.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3259 a         2145 c         2282 g         3310 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttggc
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagcat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctatttacaa
    10981 aaaacctgtc aaaacc
//
LOCUS       DARYLJ010000059        10945 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYLJ010000059 DARYLJ010000000
VERSION     DARYLJ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10945
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..255
                     /locus_tag="TU746_001723"
     CDS             <1..255
                     /locus_tag="TU746_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL0892039.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
     gene            339..518
                     /locus_tag="TU746_001724"
     CDS             339..518
                     /locus_tag="TU746_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL0892040.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            537..1964
                     /locus_tag="TU746_001725"
     CDS             537..1964
                     /locus_tag="TU746_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL0892041.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            2136..8966
                     /locus_tag="TU746_001726"
                     /pseudo
     CDS             2136..8966
                     /locus_tag="TU746_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            9476..>10945
                     /locus_tag="TU746_001727"
     CDS             9476..>10945
                     /locus_tag="TU746_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
                     /protein_id="HEL0892042.1"
                     /translation="MRTAKTILTVIHERGKQDKPLERVYKLLFNRELYLIAYAKLYPN
                     NGAMTKGVTEETIDGMSIQKIDMIIEQLRQETYYWRPARREYIPKKNGKHRPLGIPVW
                     SDKLLQEVIRMILEAYYEPQFSEHSHGFRPKRGCHTALQEIQTWKGTRWFIEGDISSY
                     FDTIDHDVLITMLSRQIQDGRFIRLIKNMLEAGYLDDWKFHKTISGTPQGGVISPLLA
                     NIYLHQFDKWVGEELIPQYTRGKKQKANSAYNRLSRRIKCYQDKGDYKKAHQLIVERR
                     NLPSVDTYDTSYRRLRYVRYADDFILGFTGSKAEAKAIKKQIGDFLNTKLSLELSQEK
                     TLITHATGESAKFLGYEIKAQRVNDYIDNKGRQSANGVIALFVPASVIESKCRQYMKN
                     GKAIHRNNLLHDDDFSIVQTYQQEYRGLVQYYILAQNLSWFSKVYWYMETSLLKTLAF
                     KHESSINKMLAKYKTTTTSTNGRTVPCLQVVVSREDKPPL"
BASE COUNT         3978 a         1598 c         2452 g         2917 t
ORIGIN      
        1 cagttcacaa gggcagggat tattgaaaac ttaatcttta agggatttgt agaaagagat
       61 aagaaaaacc ttatagccac acataaagga ataagccttg tagcgattgt agctgataac
      121 tttaagtcgg cagaaactac cgcaaaatgg gaaatggaat tatccgatat tgctcaaggg
      181 aaatcttcaa aggaagaatt tttagaagcg attgaaaatg agataaaaga agcggtttca
      241 acttatagta agtaagatga cactaatttc agagtagaaa aaatatctta aaagtgctat
      301 aatcttttgt aggaaaagta gggcgaaagg gattagtcat gaaagataca tttatagata
      361 ctgctaaagt tatgtcaaaa ggacaggtta ctattccaaa gaggattagg gaacttttga
      421 atttagaaaa tggagactat gttacttttg tagttaataa agatagagtt gaaattcaaa
      481 attccaatgt ttttatcgaa gaaaacatta agaaataaag gtggtgaaat aaacagatga
      541 cgatagatga aattaagaag ttaattcaag ccggagaaaa aatagatgtc gaatttaaag
      601 aatccaagaa cgctttaacc aaagatgtct ttgatacagt atgctctttc aacaatagaa
      661 atggcggaca tattttactt ggtgcaaatg ataaaagaga gatcgttggt gttagtgaag
      721 ataaagtaga taaagtgatt aaggaattta ctacggcaat caacaatccg caaaagatgt
      781 atccaccact ttatttgctg ccggaaactt ttgaaattga ggggaaacaa gttatttata
      841 taagagttcc tgaaggttat caggtatgca gacataacgg aagaatttgg gataggtctt
      901 atgaagggga catcaatatc acagatcatt cagagcttgt atataagcta tatgcaagaa
      961 aacaaggaag ctattttgtt aataaggtat atccgaatct tgatattgat tttcttgatg
     1021 cttctgtcat tgataaagct aagaaaatgg ctgttttccg aaataaaaat catgtttggg
     1081 aaaatatgag taatgaggag cttcttagaa gtgccaattt gatactgaca gatccggaaa
     1141 caaagcgtga aggaatcaca ttagctgcta ttttgttatt tggaaaagat aactctatta
     1201 tgtccgttct tccgcaacac aaaactgatg ctatattcag ggttgaaaat aaggatagat
     1261 atgatgatag agatgttgtc ataacaaatc tgattgacag ctatgacaga ctgatagaat
     1321 ttggacaaaa gcacttgaat gatttatttg tcttggacgg aattgtcaat gtcaatgcaa
     1381 gagacaggat actcagagaa atagtttcca atacgctggc tcatagagat tattcaagtg
     1441 gttttcctgc aaagatgatt attgacgatg agaggattac agttgaaaac agcaacttgg
     1501 ctcatgggat gggagcttta gatttacaga agtttgagcc atttcctaaa aatcctgcta
     1561 tatctaaagt ttttagagaa ataggtcttg cggatgaact tggttcagga atgcgaaata
     1621 cctacaaata cacacagctt tattcaggac aaaacccgct atttgaggag ggagatatat
     1681 tcagaacgat tattcctcta aagaagatag cgacacaaaa ggttggaggc gacaatgtcg
     1741 ctcacgatgt cgctcagggt gtcgctcacg atgtcgctca cgataagata gctctcgcag
     1801 agtttattaa agaaaaagtg agaagcaatg ataggattac aagaaaggct attgcagatg
     1861 aagctggagt tagcgtaaag actatcgaaa gagctataaa ggaaatagat aatctgaagt
     1921 atgtaggaag tggtaatagc ggacactggg aactgaatga ataaaattaa gttgcaaaac
     1981 aaagattttt ataaataaga gggtgctatg aataccataa aatgaggatt tgtagtagga
     2041 aatttaagtt gcagcaagtt gcaatacaca gaatcaaaag gtgattagag taaaatctaa
     2101 ccgccttttt tgtttggaaa aagaaggagg taaaaatgcg aataaatgat tttcataaca
     2161 ttttggagct tgtaaaacaa aatattttgc aaagtgaagc agaatacctg aagctcctaa
     2221 aggttgtcgg aaacaatcaa agatatgact ttagaagtca gttaagtatt tatgatagaa
     2281 attctgaagc gacagcctgt gccaagttcg actattggag ggaacgcttt aaccgtactg
     2341 ttatgagagg acaaaaaggt atccccattt tagaggacta cggcacatac aaaaaagtgg
     2401 catatatctt tgatataagt cagacggttt caagaaatag ggatgtcaat gaggtcaatc
     2461 tttggagatt tgataaagaa gctcataggg atgtcttaaa ggaaatgata aaaaacgagg
     2521 gctatgagga aagtgaaagc accttagaaa atatcttttc tttaagtaga ctctacggtg
     2581 atgaaaagat agacagcctt atgaatgagc ttagaatagc tgatgaggat agaatatctt
     2641 ttaccaagtt tgtgagggac tcagtgagtt atgcagtagc ttcaagattt aatgtagact
     2701 atcctatgga taatgagctt ctaaaggaaa actttgcaat gcttgatagc atttccctta
     2761 tgagtcttgg tgaaatcgta tcggatatta gtggaaagat tattgatgaa accattcaaa
     2821 aaagcaaaga gcttgagctt caaaaagaag ttttaagagg aaaagaagca ggatataata
     2881 ggattaaaga aaaaattgag aaaggagata atgatgtact tcgacgagat gatcaggaaa
     2941 gaaatgaaaa tgagcgagtt ctccgaaatg gagagtacgg acgagataat agagaaaatc
     3001 agggagaata cactaaacag cttggaggaa cagacggact tcataaggga gtatccgaat
     3061 ccgacctacg cagtaatgag gctggattac ctttcagaga gcgaggagca gagccacttc
     3121 gagatgttag tggatctata caaggagagg aagctaacag gacacctgat ggatattcag
     3181 aaacaggcga tagactttat gaggacagag aagccgaaat tgatggtagc ttggaagata
     3241 gaggacgaga acgatccgca gtatggggcg atgatttcag ctctgaagga aatgacaatc
     3301 aaggaagtat taaaaattta aaagataata ctgagataga gataagagaa gctgaaaagg
     3361 cttctttttc tttacccgaa aattcatatg gacagatgag acttaccatt ccattaactc
     3421 agagggatat agatactgtc cttattaacg gaggaaatca cgatggaagt agacttcctg
     3481 ttatcgctga gttttctaaa ggaaaaagta atgaagaatt aggagaatac ctaaaagata
     3541 tatttagagg cggtaatgga ttttacattg atgaaagaga agtatcttcc tggtattcgg
     3601 ataaaggcat tcatttagcc tacgggacat ctgcaagaga agatactacg caaattttaa
     3661 gctggagcga tgctgcaaag aggataaatg agcttcttga taatggtgag tttgctacaa
     3721 atgtagagat ttctgaggct cctgattatg aaagagataa gatttcagag tccttatggt
     3781 atctaatgca tgatttaagc gaagaaggac aaggatattt tgaactattg aaaacaagtg
     3841 gaagaggctt tccggaagaa acaaaaagat tgtctgaagc attaaaaaat cccgactacc
     3901 taaaggaaac gatcaaagaa tacagcaggt ttttagaagg atacaaagaa aacagaaatg
     3961 tattaaggtt tcactatcac aaggtagata gcctttgtca gaggttacag gaacttgagc
     4021 tgtcacgaaa ggaatatagt accaatctaa cagagcttcc gaaggtaaag tccttcatta
     4081 cagaagatga agtccttgaa agtctttcaa gaggaagtgg cgtcgataga ggaaaagagc
     4141 gaattacaaa gtttttcaaa gaaaatcata ccttgcagga aaaagctaat ttcctaaaag
     4201 acgaatatgg cataggtggt agaagtcatg cagtatcggg ggcaatggga agtgatgaat
     4261 ggcatgatgc aaaggggctt aaattacaga agaataattg taatgatgtt tttcttactt
     4321 ggtcaagtgt ggcaaagcgt atagaggagc tgctttctaa aaatctgtat gaagaaaaga
     4381 aaatagaaag taagtcagag gtagaagaat caaaagagct acaatattat tctaaagata
     4441 atcctgaaaa cttaatgact gatgaaatgc ttgaaagagt gcctgagctt tacgcacagg
     4501 aagatgtagc tttagcggat aaagaggttc atgcagcata tattattcct ttccgttcta
     4561 actggacttg gtatatgacg gaatatgata gggaaagcgg tgatgccttt ggacttgtgt
     4621 taggatttga acctgaatgg ggatatttca atcttgaaga attgaaagaa ttaaatgctc
     4681 aaaggcttat tttagaggat tttccaaaga cttttagaga gcttaaagat acagaacttg
     4741 caaagcagat ggatgaacag gaacttcaat cagtctttaa cggagaactt agctttgaag
     4801 ataaagaaga acttgaaata tctgaagaag tggaagaaag agtagctgca acacctgttc
     4861 aggaaacact atttgattat ctgaaggaga aggaagaagt agagcttaac gaagaaaaga
     4921 aaagtatttc agatgaattt gcagttaaag agggcgatac cgtctatttt aatcatgaag
     4981 aatatactgt aagggaaatt gctgaaaata aaatcacaga aagatatgac ttatggcttg
     5041 atccgggaag aagtggaaac catcaaatcc ctattgtagc ctttacagat aatgaagatt
     5101 tattaagaca agtaagccct gaaagacctg cgtttatcgt tggagatgaa attaaataca
     5161 aggataaaga ctataccatc acacgctttg acgatatggg aaataatcta aagacggtaa
     5221 cggttaagga taataccgaa tatcttggcg gtatgataac aggctcagat gtaattcctt
     5281 atcgtcttga aagcgatctt gagagggtat ttgaaaatct gacatataaa aagcctgaaa
     5341 ctattgctaa agaaagtgaa ataaagaaag cagaagctca taacttcaag attacggaag
     5401 aaacattacc tgacaagtta tctccaagtg aaaggctaaa taataacctt gaagccatct
     5461 ctatgctgag tcgcatcgaa agtggacaaa gagagtttga cagtacagct caggaagttt
     5521 tagcaaggta tgtaggctgg ggtggacttg ctgatgtatt cgatgaagaa aaaggcggac
     5581 agtggaaaga agcgaggagc tttctaaagg aaaacttatc tcaggcagaa tatgaagctg
     5641 caagagaatc taccctaacg agcttttaca caccgaaaac tgttattgac ggcgtatata
     5701 agacactttc cgatatggga tttaagagcg gaaatatcct tgagccatca atgggcatcg
     5761 gaaactttat aggaaatctt cctgatgaaa tgaacaagtc aaagttttat ggtgtagagc
     5821 ttgacagtat aagcggtagg attggaaaac ttttataccc tgaaagtgat atacagatta
     5881 aaggacttga agaaacttct ttttccaata acttttttga tgttgcaatc ggcaatgttc
     5941 cctttggaga atacaaagta aatgacaggg aatacaatcg taataacttc cttattcatg
     6001 actatttctt tgccaagtcc attgataagg ttagaaacgg cggggttatc gcctttatta
     6061 catcaagtgg aacaatggat aaaaaggatg aaagtgtaag acgctatctt gcagcaagag
     6121 cagagttttt aggagctatc agacttccta atgacacctt taagggtact gccggcacag
     6181 aagtaacctc agatattatc ttcttaaaga aaagagatag cgtattagag cgtgatgaag
     6241 attggataca ccttgcggaa gatgaaaacg gtcttgtata taacaaatac tttgttgatc
     6301 atcctgaaca ggtacttggc tcaatgcgtg aagtaagcgg aagatttgga aaaactctaa
     6361 cttgtgaacc gatatcttat ttaggcacag agctaaatat ggcttcatta aaggatcgta
     6421 tcgagattgc aggagaaaga atttcaaaag atgccaagta tgaagaaata gagcttttag
     6481 atgatgaaat cacttcaatc cctgcaacgg atgatgttaa gaacttttcc tataccatta
     6541 ttgatgatga agtctattac agagaaaact cactgtttat caaaaaggaa gtaaccgata
     6601 aaaacaaaga aaaaatcaag gattatcttg agctgaatgc tgccttaaaa aatgtgattt
     6661 acaagcagaa agaaggtttt agtgaggaag aaatcaaggc ttcacaggaa aaactaaatg
     6721 aagtctatga ccgtttttct aataagcatg gctttgtaaa taatttaagc aatacaagag
     6781 ctttaaaaga ggatagcaac ttcccgcttg tttcctccat tgaaatcctt gatgaagaaa
     6841 actttaaggc aaagggagat attttctcca aaagaactat tacaaaggct aaagtcatag
     6901 atcatgtgga tacttcttta gaagcccttg tcttatcggt atctgaaaaa ggatatgtgg
     6961 actttgacta tatggaaggt cttacaggaa aagacagacc gactttgatt gaggagcttc
     7021 gaggggaaat ctacttaaat attagggaag aacaaaactt ttatagacct ctatccttta
     7081 accccgaaga tggagatttg ccttttgcct gtgccaatgg cagtaattcc tacaaatacg
     7141 gctatgtaac aaaggatgaa tatttaagtg ggaatatcag ggacaagatt gccatagtag
     7201 atagctatct atcaaagctc agacagacgg aaagagagtt acctcatctt ggctatgcag
     7261 aagatggtaa agaaaaagag ctgattagct atgagatgaa tcgtttggaa taccaaaagg
     7321 ctgagcttac aaaagttcta ccaaaggagc ttgaagcaag tgagataagt gttcgtcttg
     7381 gtgcgacttg gataccgatt aaagatattg aaaaatttat ttttgaaacg ctgaaaactc
     7441 cgggatatgc aagatgggat attaaggtta agttttcaaa cctgacaagt gagtggaata
     7501 tagaaggtaa aagtagggat agaggaaatg acctcgctga aatgacttac ggtacatcaa
     7561 gggtaaatgc ctataagctg attgaagatg ccttaaacct gaaagaaaca aaggtatttg
     7621 accagattgt aaatccggac ggctctaaaa cttctgtact aaataaaaaa gaaaccatgc
     7681 ttgcagggca aaagcaggaa ctactaaaag aagaatttaa gaactggata tttaatgatc
     7741 aggagagaag aaaccgtctt gtaaaactgt ataatgagcg ttttaactct atccgaaaca
     7801 gagaatatga cggaagtaat ctttcctttg agggaatgaa tactaaaata gatttaagac
     7861 ctcatcagag aaatgccata gcaagaagtc tttatggagg caacaccctg cttgctcatg
     7921 tggtgggcag tggaaagacc tttgaaatgg tggcttccgc aatggaaagt aaaagacttg
     7981 gaatgtgtag taagtccttg tttgttgtac ccaatcactt aacaggacaa atcggtcgtg
     8041 agtttatgca gctatatccg tcggcaaata tcatggtggc agataagaaa gattttgagc
     8101 cgaagaaccg taagcgtttt atcggtcgaa ttgccacagg agaatacgat gccgttgtta
     8161 tcgggcatac gcagtttgaa aaaattccta tgtctaagga atatcaggag aagcatatcc
     8221 aagatcagat tgatgaaatc gtaaactatg tagaagaata caagcatgac agaaatcaga
     8281 actttacagt aaaacagctt gaaaagacaa agaaaaaact ggaaacaagg cttgagaaat
     8341 taaatgacga ttttaagaaa gatgatgtca ttacctttga ggaattagga gttgataagc
     8401 tctttgttga tgaagcacac aactacaaaa atctctatct ttatacaaaa atgcgtaatg
     8461 ttgcaggaat cggtcaaagt gaagccttta agtcctccga tatgtttatg aagtgtcgct
     8521 atatggatga aatgacaaac ggaaaaggca ttgtctttgc aacgggaacg cctgtatcaa
     8581 actccatgac tgagctttac actatgcagc gttatcttca gtatgagagc ttaaagaaaa
     8641 ataatctgga gcattttgat agctgggctt ctacttttgg ggaaacgcag tctgcttttg
     8701 agctttctcc ggagggaaca ggatacagag taaagacaag attttccaag ttctataact
     8761 tgcctgaact aatgtctatg tttaaggaag tcgctgacat tcaaacagcg gatatgttaa
     8821 atcttccaac acctgaggca cattatgaag taattaagac cttgccaagt gaggagcaaa
     8881 aggaaattct aaagagcctt tctgaaagag cagatgatgt gagaaatagg gtggtagagc
     8941 ctgacaaaga taatatgcta aaaattgtgc gctgttaagc gtaaaaatgt atctccctca
     9001 cagagggata ttattgaaag taaataatag gaacaactaa ctaacctagc ggggaaaccc
     9061 aaaggggaca atagcatgtt agtaaagcgg ataaggagtg agttacaacg ctttgatgtg
     9121 ccgcaagttc cgtaacctat ggttaaggct aaactgcttg aacctcaatt ctgactaggt
     9181 gcaaagcatc gcccatcgga aagtaactga gaccgatgtt actgtatatt cgttgttgtg
     9241 attttggacg aataactttc tacagtaaaa gagcatacga taagtatgaa taaaggaatg
     9301 agtgaggaac ctaagggtta ctagaacgta catttttaac gaatagcagg attgcctaag
     9361 aggggggacc cttatggtaa cggagtcacc gtagtagtcc gagcaaggga aatccttgta
     9421 catggcgaag ggtgacaggt aatttcgatt agttagaaag gattaggtgc gtgggatgcg
     9481 tacagccaaa actattttaa cggtcattca tgaacgtgga aaacaagata aaccactcga
     9541 aagggtttat aagttactat ttaatcgtga actctatctg atagcctatg caaagttata
     9601 cccgaataat ggagcaatga caaagggtgt tacagaggaa acgattgatg gaatgtctat
     9661 tcaaaaaata gatatgatta ttgaacaatt aagacaagaa acctattact ggagaccagc
     9721 taggagagag tacattccta aaaagaatgg aaaacaccgt cctttgggaa taccagtatg
     9781 gagtgataaa cttcttcagg aagtgattcg catgatatta gaagcctatt atgagccaca
     9841 atttagtgaa cattctcatg gttttagacc aaaaagaggg tgtcatacag ctttacaaga
     9901 aattcagact tggaaaggga cacgttggtt catagaagga gatatctcta gttattttga
     9961 cacgattgac cacgatgtat taatcactat gttgtctaga caaattcagg atggtcggtt
    10021 tattaggctt atcaaaaata tgcttgaggc aggatatctt gatgattgga agtttcacaa
    10081 gactattagt ggaacaccgc aaggtggagt tattagtcct ttattagcta atatctattt
    10141 acatcaattt gataagtggg tcggtgaaga gctgatacct caatatacaa gaggtaaaaa
    10201 gcagaaagca aactcagcct ataatcgttt gagtagaaga attaaatgct atcaggataa
    10261 aggagattat aaaaaagctc atcagttaat tgttgagaga agaaatctcc cttcagttga
    10321 tacttatgat accagctatc ggagattaag atatgttcgg tatgcggatg actttattct
    10381 aggctttaca ggttcaaaag ctgaggcaaa ggctataaag aagcaaattg gagacttttt
    10441 aaatactaag ttatctttgg aactttctca agaaaagact ttgattaccc atgcgactgg
    10501 agaatcagct aaatttctgg gatatgagat aaaagcacaa cgtgtcaatg attatattga
    10561 taacaaaggg agacagagtg ccaatggtgt tatcgcatta tttgtacctg catcagttat
    10621 tgaaagcaaa tgccgccaat acatgaaaaa tggtaaagct attcatcgta ataacttatt
    10681 gcatgatgat gactttagta tcgttcaaac ttaccaacaa gaatatagag ggctagttca
    10741 atattatata ttggcacaaa atttgtcatg gttctcaaaa gtctattggt atatggaaac
    10801 atcactcctt aaaacattag catttaaaca tgagtcatcc attaataaaa tgttagctaa
    10861 atataagact accacaacta gcacgaatgg ccgaacggtg ccgtgtttac aggtagttgt
    10921 gtctcgagaa gataaacctc ctcta
//
LOCUS       DARYLJ010000060        10617 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYLJ010000060 DARYLJ010000000
VERSION     DARYLJ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10617
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TU746_001728"
     CDS             complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TU746_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL0892043.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1772..2485)
                     /locus_tag="TU746_001729"
     CDS             complement(1772..2485)
                     /locus_tag="TU746_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL0892044.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQFAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2506..3153)
                     /locus_tag="TU746_001730"
     CDS             complement(2506..3153)
                     /locus_tag="TU746_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0892045.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TU746_001731"
     CDS             complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TU746_001731"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL0892046.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TU746_001732"
     CDS             complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TU746_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL0892047.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6592..7374)
                     /locus_tag="TU746_001733"
     CDS             complement(6592..7374)
                     /locus_tag="TU746_001733"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL0892048.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TU746_001734"
     CDS             complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TU746_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL0892049.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            complement(8802..9434)
                     /locus_tag="TU746_001735"
                     /pseudo
     CDS             complement(8802..9434)
                     /locus_tag="TU746_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9436..10203)
                     /locus_tag="TU746_001736"
     CDS             complement(9436..10203)
                     /locus_tag="TU746_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL0892050.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(10485..10617)
                     /locus_tag="TU746_001737"
                     /pseudo
     CDS             complement(10485..10617)
                     /locus_tag="TU746_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT         3132 a         2398 c         1945 g         3142 t
ORIGIN      
        1 gtcctctcca gatgttagct tgtcaactac ccactacagt tgacatggag cctgattata
       61 ccgttaaata agctgccaga tcagctaagg cacgtttagc gatagcttca tagcgttcct
      121 ttttatctct gatacgaggt ccgtcaagct ctttaataat accaaaattg acattcattg
      181 gttgaaaatg cttgctgtcc gcgtgtgtaa tataataagg caggctgcca attgctgttg
      241 tatttggaaa aacaagtggc tcttcttcct tgaatagccg agcagcatta atgccagcca
      301 caagtccaga agctgctgac tcgacatagc cctccacacc ggtcatctga cctgcaaaga
      361 aaagcctgtg attagcgcgt gattggaagc cttgtgtcag aagctttggt gaatccatat
      421 aggaattacg gtgcatcaca ccgtaacgca caaactcagc atgctcaagg cctggaatca
      481 tttggaaaac ccgcttttgc tctccccatt ttaaatgtgt ctgaaagccc acgatattat
      541 aaaggctgcc tgcagcatta tcctgacgca gctgcacaac agcatagggc gtcttgaaat
      601 caccgtcacg tggtcccttg taatcatctg gatattccaa gccaaccggc ttcattggac
      661 cataaagcat agtcttaatc ccacgctttg ccataacctc aattggcata cagccttcaa
      721 aatacttttc cttttcaaaa gcatttaaag gagcttcctc tgctgttgtc aaagcctcgt
      781 gaaaggccat aaactcttcc ttggtcattg gacagttcag ataagcagct tctcccttat
      841 catatcgcga ttttaaataa accctatcca tgttaatggt tgacttatcg acaattggag
      901 ctgctgcgtc gtaaaaataa aagccagcac caccatttaa ggcatgtatt ttttcagcaa
      961 ggctgtcact ggtcaagggg ccagttgcaa ttactgtaat agcatcgcta ggaatgtcaa
     1021 taacctcctc acgaatgatt tcaatcagag ggtgattttc aagctcagct gtaacagcct
     1081 tggcatagcc ttcgcgatct acagccattg ctcctccggc agggacacga tgggcttcgc
     1141 cagcacgcat aataatcgaa tccagacgac gcagctcttc ctttaaaagc cctactgcgt
     1201 tggttaagct gtcaccacga aaagagttgg agcaaaccaa ttctgcaaaa tgggtggttt
     1261 tgtgttgcgg tgttgccttg acaccacgca tctcatatag cttaacagga ataccacgct
     1321 tagcaatttg ataagctgcc tctgatccag ctagaccagc accaataaca ttaatataag
     1381 attgagacaa tagaccaata cctctttggg gacttatcca tcactgattg ccccgcaact
     1441 ctttctttca agtaattacc ctgcctatta taacagaaat aagagcaaag caaaagaagg
     1501 agctgaacag cctcagtctt ttatataaag gagataagcc cgtacctgca cgctctccac
     1561 aaagctagct gcttcaagca ttttagcttt cgcccaatac cagctatcca catatcttgt
     1621 tcactgcagt agttactgga aggcttttta aggcttattt ttcaaaatct agccaaaaat
     1681 atttcaccgg acctcatcat cttgctggta gcagctaaac aagccttttc cagtaaaaaa
     1741 aaagcaagcg aaagcctgcc cttgttcttg tttagaaaaa acacatccat gctgcgataa
     1801 agacacttaa gacactaaac agcgatccaa tcaaataata ttcagcaaag gctgggcttt
     1861 cagagatttt attgtagcga gcaatagact tagcggtaag caccagtccg attgaagcaa
     1921 attgtcccaa caccatacaa acgcccataa caatacgctc taaattacca atagccgcac
     1981 ccgcccctac aatggtatcc attggtttat cactagctgg ctggaattta ttgaagcaga
     2041 gcttaaagat aatattgaca ggcttggtga tcaaaaccat aaaaagcact aacaataact
     2101 gccgagcatg taaccaatca gggatctcag cctgattaac acgagcgact aaagccagaa
     2161 taatgaaaag atgcaagagc tggtccaaca caaagaccca cgaccgatca agcttaatga
     2221 tacgagccca ttttggctta aaataatcaa taaccgcatg gctactaaaa ataaggatcg
     2281 ctgttagcca aagcttaggt atacacatca ccactagaaa caatggagca gctaccccta
     2341 ataagtgcag ccccagataa gcaaactgct cctccttctt atcagcaata acctgactct
     2401 gaaggtgata atctgataaa aaatgacaaa tcactagcag cactaaaata ggatgctgat
     2461 aaaggtaatc agataagccc tgcataggtg gctcctttcc tctttttatt cttgtaggta
     2521 ggtcaaagct gcatggcgac ttctaagata aacctttaca ctgctgcttt ttaagcgctt
     2581 tgacaaggca cttgattgga ggtccaatgt atcgccaatg agctgttggt caaattgttc
     2641 ttcatagatc cctaagtcta aaagcgcatg aaacacctct aattgactag cacgccagct
     2701 agcttttatc gcctcaccag ctgctaaaag gctattgagc accagatcct tgtgctcctt
     2761 atcagtccgt atagctacct gggtattgcc ataatcattt ttttgatgaa tgtaatgaat
     2821 agcctctctg gcacgccaat aggctggacc gtcagcacca atactaatat cagggttaat
     2881 atcagtcaaa atagtcccct gtccaatacc aaacctaaca gggtagcctg tcatggcttg
     2941 attaattaaa tcaatgagtt gaaaaacagg cgcatcatta gtcaacaagc cttgaaattc
     3001 atcacccaga gtcacagata agttagagac gatataggaa gaaaaatcat ggttgagctg
     3061 atccagacag gcctttaagg actcttgcac caaagaacgc gactgaattt gcttagaatg
     3121 gaccaaatcc ccaataacag cgatatatag catgattttc cctcctttta tgacttccat
     3181 tataacagac aaaaaccaaa aagtccatta taatggaaaa tcatctatat ttccgttata
     3241 atggacctct gctaaaatag ttcaaaccta ctttacaatc tcttctttat agtcacagac
     3301 ttcattgcta cacacaacct gcttacctcc acgaattttt ttctcaacaa ggtaatcgcc
     3361 tgacttcgga caagaccgtc ctaccggcaa atcccacgag gtaaagtcac actcagggta
     3421 gcggtcgcag ccatagaaaa tacggttacg ctttgttttg cgctcaatga cttggccttg
     3481 ctgacaagct ggacaagaaa ctccaatttc ctttgtgatg gcctttgtat gatggcactc
     3541 aggaaagtta ctacaagcat aaaacttgcc aaatctaccc agcttaacaa ccatcgggtg
     3601 gccgcacagc tcacaatcaa aaccagccgg ctcgtccttg atttgaattt tttcgatctc
     3661 cgtttcagcc ttggttaact ccttaacaaa tggcttgtag aattggtcaa tcacattctg
     3721 ccaggcttct ttgccgatct ctatctgatc aagcttatct tccatatcag ctgtaaattt
     3781 gacatcaaca atatcaggga agaattccac aatcaattga ttaacaattt cgcctaattc
     3841 cgtcggctca aagcgtttag cagccagctt aacataataa cgacgctgaa tcacatcgag
     3901 tgttggagca taggttgatg gccttccaac accgttttct tccagtgttt taatcaggct
     3961 tgcttctgaa taacgagctg gcggttgagt aaagtgctgt tcaggtgtta aggtaacctt
     4021 tttaaccact tctccttctg tcatttcagg aagcatcttg cttttatcag aatcattgta
     4081 aacagccata taaccgtcaa atttcatctg actgccattg gcaacaaaaa ggacactatt
     4141 ttgctctagg ttaaccttaa cagtatcaaa cacagcagct gtcatctgac tagcgacaaa
     4201 gcggttccaa atcaaggtat agagctttag ctgatcctta tctaaaaatt tagcaatagc
     4261 ctctggcgta tggttcacat tagatggtcg aatagcctca tgagcgtctt gagcaccagt
     4321 agcattttta actcgattgc catgcttaga gtactgacta ccgaaacgtt caacaataaa
     4381 gcctgcggca tcattttgag caactgggct gatacgagta gagtccgtac gcatgtaagt
     4441 aattaaccct tgtgttccat taggaccaag actaatcccc tcataaagct gctgagcaac
     4501 catcattgtt ttacgagtcc gaaagttaat cttattggct gcgtcctgct gcaatgagga
     4561 ggttgtataa ggtaaaggag catgacgcct gcgttctttt ttctcaacct tactaaccat
     4621 aaaatcatcg ctacttaatc gagacaaaac aagcttaaca tcatcattgg tattgagctt
     4681 catctttttg ccattgaggc cgtaaaagct tgcttggaat ttttttgtcc cttttttaaa
     4741 gagaccatca attgaccaat attcttcagg aacaaaggcc ttaatctcat gctctctgtc
     4801 aatgattagc tttagagcaa ccgattgcac gcgccctgct gaaagcccct ttttaacctt
     4861 tttccagaga attggcgaaa tggaataacc aacaatacga tccagtacac gacgtgcctg
     4921 ctgtgagtca accaaatcca tatcaatttt tcttgggcct tcaaaagctt ctttgacggc
     4981 atcctttgtg atttcattga aaacgacacg attgttatca tcaggatcaa gtcccaaaat
     5041 atgtgataaa tgccatgaaa tggcctctcc ctcacgatcc gggtcacttg ctagataaac
     5101 ctttttagca ttctttgctt ctttttttaa ggcattaatc agcggaccct taccacgaat
     5161 attaatatac tgtggctcat aatgattgtc aaaatcaata gacattgatg attttttcaa
     5221 atcacgaata tgaccaaccg aggcaacgac cttatactga cgtcccaaat atttttcgat
     5281 ggttttagcc ttagcaggtg attcaacaat gactagattt tttttagcag ctgctgattt
     5341 tttctttgta gcagatcttt tcgtctcttg ttttgactta gttgctgttt ttgttaccaa
     5401 ttgacacact tcctataaca gttatggtta aagcttctag cataatatcc cattttttaa
     5461 gaactgtcaa caaaaaattt tctataaata ggaagaaaag ttaagaatag tggtattctg
     5521 aaagaatgtc tctgccatga gtgacacagc tggcaccatc tttgatcagc ttcaaacagc
     5581 ccgccgatgt cccattaaga atattgtcag gtacgacaaa aatatcacgt ccctcttcca
     5641 tagctagctg acaggtaatc aaagagccag agcgctgctt agcctcaaca acaaggacac
     5701 ctcgactaag acctgcgata atacggtttc tttcagggaa atgataagac aaggcggcct
     5761 ctccagcccc atattcactg agcacgagat gacgctgaga taaaaactcc tgtagctggt
     5821 gattttcctt tggatagtag cgatctaggc cagtcccgat aacagctatg gtttgcccac
     5881 ctgctttcaa gcaagcgaga tgagcactgg tatcaatacc tctagcaagc ccgctgacaa
     5941 tgacaaagtg attcttaagc tctttgatga ttttgtaaac agaccgcgtc ccaatttcac
     6001 tggattctct agagccaacg actgccagct taggcttttc taacaggctt aaatcacctt
     6061 gataaaagag taaaacagga ggattataga tttccctcag ggccaatggg tattgcttat
     6121 ctaggataga taagctcgga aactggttga attccttttt taacaaggcg acatttaatt
     6181 gcttgtaggt ctcaataaat aaaactggat ttttgcagca agaaaccact gccatatctc
     6241 taagggatag agacttgtta ttacgctgct ggtagtcaat caggttaaga atatttaaat
     6301 tagttagccc agcctttttt aatttataaa gttcaaaatt attcatcact gtacctctct
     6361 aatgatttat tcgtaaaaaa attaaaaaag ctctgactaa acaaagcttt ttgcaaactc
     6421 ttgaggagct gtacaggatt ccagcaaaaa aatcgaggcc tcctagcctt tgtatgagca
     6481 ttgtagggca gctcatcaca tagcattcca ttgaaaaata ccagaattgt agatccacct
     6541 agtggctatc gtttttgctt tcggcagcta ccttttctca aaatgagatt tttagcgtaa
     6601 gatcattgat tttatcggct caaagctttg ccgatgaatt ggtgtgacac catactggtg
     6661 caatccctgc aggtgctcct tggtcccata gccggcattt ttagcaaagc catagcctgg
     6721 aaaggcctta tcgtaatcaa gcatcaatcg atctctggta accttagcca caatagaggc
     6781 tgcagcgatt gacatagagc tcgcatcgcc ttttataata gcctgttgag gaatagaaac
     6841 ctctagtgtc atggcatcaa tgagcaggta atcaggctta ctcacagagc cctccagctg
     6901 attaatggca gctgtcattg ctaattttgt tgcttcatag atattaaccc ggtcaatggt
     6961 atggttgtca ataattccaa gaccgattcc caacgctttc ttttgaatgg cttggtaaat
     7021 tgcttcatgc ttagctttag gaattttttt agaatcattt agccccttaa tggtgcagcc
     7081 ctttggcagt ataacacagg ctgctacaac tggtccagcc agaggacctc gaccaacctc
     7141 atctatacca gcaatcgctt gaaagccttt ttggtaaagc gcctgttcat acgtcaacat
     7201 cgcctcaagc cgggcttcct cttttaagat agcctctaaa gccctttttc tgctagatac
     7261 agccttttga acgccaagcc gcttatccgc ctttagctct tcaaaaaatg gatcagaaag
     7321 actagaaaca gcttctagac gagctttaat gtctttaata gtcattgctg tcatcatcac
     7381 caacctgatc taaggtgtac tgaccaagtc ttccatcacg aatatccttg atgaataagc
     7441 tgtaaaaacg atcatagtct tccttaaagc caagctgacg tgtcaaggac atgatgattt
     7501 ctggagcgtc agcctctaga tcaatagcct taaaacgctt taataggcga ttaggataat
     7561 acttcttaaa ataattcaat ccaaaaatcg tgacctcgtc cattggcaac agctgatcct
     7621 taatagcccc tgtcagggct aattttaacc caaccaattc gtcttcaaac tttggccata
     7681 agatacccgg agtatccaat atctctagtt ctttattgga ttttagccat tgctgtccct
     7741 tggtcactcc tggcttattg cctactgtgg caattttttt tcccgccaag cgattcatca
     7801 gggttgattt gccagcattt ggaatgccaa taatcatggt tcgtagcgtt tctttttgaa
     7861 tgcctcgttc tcttaagcga cgtagtttat ctgccatcaa ttccttagca gcctcggtga
     7921 cccttttgac cgtagcctgt tccttagcat tgatagctaa tgtcttaatc ccttgcttct
     7981 cataatattg ttgccatttc ttagtatgcg tgttatctgc tagatcagcc ttattaagaa
     8041 gcattagctt gggcttatct ccaacaattt tggtcagcat aggattttga cttgataaag
     8101 gtagcctagc gtctactaaa atcgtcacaa aatcaacatg cttaatattt tcctgtacct
     8161 gtctccttgc cttggacatg tgtccaggaa accattgaat cgtagccatg tgtgtaaaat
     8221 cctttcgtat caagggtttt tagcccctcg tcttttaaaa atcatgcgag tcaccaaaaa
     8281 atcaccaaat attaagcatt atctccagac caagcgatat aattgcaact tgttttggtt
     8341 atttttaatg ccaacaatat caaatgattt ctaatggtat ctggcttata gctattctct
     8401 gctgaataga ttgcctcttc aattttaccc tgtaatctcg ctcagcctgt ctcctgacct
     8461 tgcttttaca tatgaaactg taatattttc cattttacca gttatatgat aaagaaaatc
     8521 aaaatagtcg tagtagaata aattacttta aactattata gcacgatttc ccttatttta
     8581 ctgctaaatt atcctttgta aaagaagata ttaatcgtta taaagaccaa aaaagagaag
     8641 accaaaatga tcccctctag tcttcttttc ggcatatttt accgttattt ggccaacttt
     8701 ccactaatgt gagtaaaatt gtattctaag caagctttac ctattaactt aggagaaaac
     8761 ataatctcta tagctaaaaa taccaaaaaa attatgaatc attatcgcaa actatccata
     8821 gtgatcattt catcagccat ttcccatatt gctggattat gagttgctac gatgattaat
     8881 ctgttagcgt cacgaagaga cagtacaatc tccataatca acttggacgt ggttggatct
     8941 attgaagccg ttggttcatc tgccaaaata aatggcggat tttttaagat gatctttgct
     9001 aaggcaactc gttgtgacta acccccagat agctcaaaaa tgcgtttatc taggttcaga
     9061 taggataaac ctacacgttc taaggcctgt ttctgtctca tcgtttgctc agatttattc
     9121 aatttttgac caatgagacc aagtttgagg ttttcttcaa tcgtttgatt ttcaatcaaa
     9181 ccaaaatttt ggaataggta acccaattca tgacggaaaa aatcactaga tttatagctg
     9241 gctaagtctt tgtctcggta aaaaatagtc ccatgataag gttctaattt ccccatcatg
     9301 ttcatcaagg ttgttttccc gctaccgctt gaaccaatca aagcatagac ttttccaacc
     9361 tcaaatgtca ttgaaagatt agaaaatagc tctcgttctc caaaagattt actcacttgt
     9421 ttaagttcaa tcatgttaac ctcctttcaa aacaagcatg gacatcttgt tttctttctg
     9481 catttgaaca tgtaattgta aaagagatag gccagtgaag agcaacaata ctaagaaagc
     9541 aatcactatc tctacttgaa ggaatacact cgcaacaaat ccgagtaaaa agacacccaa
     9601 ttgagccagg aggtaattcc gatggatttc taaaaatctt agtccagcaa tacgtttgat
     9661 gacaatggca cgtctaaatt cttcaaagta gagcctattc atggtgttaa acaacaagat
     9721 tgaggttgct atcccaagca cagctcccgc aagcattatc caacgttccc tctggatatt
     9781 attcaacaat gtgatgtagt tctggtatcc tgattgcatt tctgagaccc aattttcaat
     9841 gccctgtctc tggataagct cctgggcatc ggacaactga ttaaagagga cataattctg
     9901 taccgcgtca aaccaaaaca tgacggactg aggtccagtt gactggggtg ttacgacaat
     9961 gataatcgga tctttcagaa actgttgata ggaaataggt gtcgtattat acacaaaacg
    10021 gtcttggcct gattccaaat aagccaccgt cgcaatcatt tgctgtcgac catcttgact
    10081 agacatgcga ctagttaagt cgtcttcaaa aacagatttg taatgttctt cctctgaacg
    10141 gagatgctca ggcaagagca agacaaattc ccctactgcg aggtgattca gtttttgttc
    10201 aatagccgta tctacaggga tgttttgacg ctccaagtat tgcggtgtga caataaggac
    10261 attgccattt gggctgtaat cttgccattc tgtagaagtt gtcaagtttt tggaaaagtc
    10321 ttagcctttg ttatcaatac ttgagtagca cctatgtttt tcagattagc ttgctcttgt
    10381 aactgttctg agctattaaa tgctgtcatt tcaacggtga tattttcagt tgattctgcc
    10441 tgcttgttat cttcttttgt tggagattct ggacgtttct caaaataaaa ataattataa
    10501 agctgttgag ccgttactcc tccaccagcc cagccagcaa caggttgacc attcttcaga
    10561 tatagtattg ttggtgttcc tgggattcca actgttttaa ataaaaactc ctgagct
//
LOCUS       DARYLJ010000061         9980 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYLJ010000061 DARYLJ010000000
VERSION     DARYLJ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9980
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TU746_001738"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TU746_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL0892051.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TU746_001739"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TU746_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            complement(5931..7601)
                     /locus_tag="TU746_001740"
     CDS             complement(5931..7601)
                     /locus_tag="TU746_001740"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL0892052.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            7799..8491
                     /locus_tag="TU746_001741"
     CDS             7799..8491
                     /locus_tag="TU746_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL0892053.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            8484..9029
                     /gene="coaC"
                     /locus_tag="TU746_001742"
     CDS             8484..9029
                     /gene="coaC"
                     /locus_tag="TU746_001742"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL0892054.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            9086..9658
                     /locus_tag="TU746_001743"
     CDS             9086..9658
                     /locus_tag="TU746_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0892055.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT         2914 a         2223 c         1868 g         2975 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt actctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc atttgtacct
     5641 gactataata atataacaat atctctttat taacaataga tttgtgaaaa attaatttta
     5701 tcatttaata ttaaaagtca gattattaaa aaatatccct accaaagcag aattaaagca
     5761 ttaatgattg tcaatatgac acctatactg gtaaaaaaag attgtgaata acgattaaaa
     5821 tagtaaaata tgagctattg ttatcagctt atccttagac attaaaaaag attgaagaaa
     5881 ccccctttct gaagctttct tcaatcctga ttctggctat aacaaataaa tcaaaacaat
     5941 cctactgctg taccgtcttc ggtgacgtcc atcttcatag ctgcaggaat ctttggcaag
     6001 cctggcattg tcatcacatc tccagttaag gcgacgataa agccggcacc ggtcttaggc
     6061 actaattcac gaatggtaat gtcaaactga tctggcgcgc ctaggagcga tggatcgtct
     6121 gaaaagctat actgggtttt ggccatgcaa acaggcaatt gatcccaacc aaactgggca
     6181 aattgcttga gctgattttt agctttaggt ccgaattgca cagccctacc accataaatt
     6241 tcagtcacaa ttgccttaag tttctcctct aagctatcct tgtctgcata tagacgctta
     6301 taggctgcgc tttcctctgt aatagccttg acaacagcgt tggcaagagc aataccgcca
     6361 tcagccccct tggcccacac gcttgccaat tcaaccggaa cagctatttc tgcacacaat
     6421 tcttttaaga cttgaatttc tgctttagta tctgtcacaa attcgttgat agctacaaca
     6481 atcggaatat tgaattttcg aatattctca acatgacgct ttaaattagc aaagccagac
     6541 cggaccgcag ctgtattttc aaaggttaaa tccgccttag caacaccgcc atgcatcttc
     6601 aaggcacgaa gtgttgcgac aataacaact gcatcaggag ccttaggtag attcggtgtt
     6661 ttgatgttaa ggaatttttc tgctccaaga tccgctccaa agcctgcctc tgtaacagta
     6721 taatctgcca accgcaaagc tgttgatgtc gccagaacag aattacagcc atgagcaata
     6781 ttggcaaagg gtccaccatg cacaaaggct ggtgtaccat agattgtttg aacaaggtta
     6841 ggcttgatgg cgtccttcaa aatcaaggct aatgcccctt ctacctttaa atcacgcaca
     6901 tatacaggtg atttatcgta acgataggca atcacaatat tagctaaacg agccttcaag
     6961 tccttaagat cagtcgccaa gcaaaggata gccatcactt cagaggctac tgtaatatca
     7021 aaaccgtctt ctcttgggac accattgaca ggactcccca agccaacaat gacctgccta
     7081 agagaacggt cattcaaatc aaggacacgc ttccagatga tacgacgcgg gtcaatacca
     7141 agctcattgc cctgctgaag gtgattatca ataagggctg ataaagcatt atgagctgtg
     7201 gtaatagcat gcatgtcccc ggtaaaatga aggttaatat cttccatcgg aagaacctga
     7261 gcgtagccgc cacctgcagc accacctttg atccccataa ccggtcctaa agagggctca
     7321 cgcaaggcca gcatggtttt tttaccgatt ttagtcaagg catctgccaa accaatagac
     7381 atggttgatt tgccttcacc tgctggcgtt ggattaatag cagtcactaa aatgagctta
     7441 ccaggcttat tgtcctctac tgatttgatt ttttcaaagg ataatttggc tttgtagtta
     7501 ccgtaaagct ccaaatcatc agcatcaatc cccacctttt taacgatttc tgtaatcggc
     7561 tttaagggga cactttgagc aatttcgata tctgatttca tgaaaactcc ttgactctta
     7621 cttgatagtg ttattatatc acacttcatc tcaaacgtac attgatttgt tctatataca
     7681 aaaatgttcg tttttataat ggttctgaaa ggaaaaaagc ttagtagcgt cagcattgtc
     7741 agtaaaaata attttaatta gtgattttat ttactattct tgctttttct gataaaatat
     7801 ggctatgaaa ttattaatca catcaggcgg aacgaccgaa gcaatagacg ccgttagagg
     7861 gattaccaat cattccactg gccagctagg aaagatagta gctgagacct ttctagcaaa
     7921 gggatttgac gttactctag tgacaacaaa aacttcagta aaaccagcac agcagcctca
     7981 tttgaccatt cgtgaggtga ccaatgttga tcagctgatg gctatcttaa aagaggaggt
     8041 tcctaagcac gaccttctca ttcacagcat ggctgtttca gattatagcc cagtgtacat
     8101 gacagacttt gatacagttg cagctgctga tcatttacag acctttttaa cagcaagcaa
     8161 taaggaagcc aaaatctcat cggcagctga ttatcaggtg ctctttctta aaaaaacacc
     8221 taaagtcata tcctatatta aggaatggaa tcctaatata aggctagtcg gctttaagct
     8281 attggtcaat gctccagctg aggagctaat ttcagtggca cgagatagcc tgcataaaaa
     8341 caaagcagac tatatagtag ccaatgacct agcagatatt aaggccaatc agcacaaggc
     8401 ttttcttgtc aatgacaaaa cagtctgctc tgccagcacc aaagaggagc ttgcacaatt
     8461 aatctatgaa aggataatag ccaatgacta agcgaataac acttgcggtc tcaggtagta
     8521 tttctgccta taaggcagct gatctcacca gccaattaac caaaaaaggc tatgaggtta
     8581 ctgtgttgat gacgcaagca gctactgcct ttatcactcc gttgacccta caggtcttat
     8641 cgaaaaatcc tgtccatcta gatgtcatgg cagagcacga tgtcaaaatt gtcaatcata
     8701 ttgagctagc taaagcaaca gatctatttg tccttgctcc tgcaagtgcc aataccattg
     8761 ctcatttagc ctacggcttt gctgataata tggttaccag tgtcgcccta gccctgcctg
     8821 aggcaacacc caaactcatc gctcctgcta tgaatactaa catgtacctt aacccaatta
     8881 ctcagggaaa catcaaacgc ttagctgatc ttggctttcg agaaatacca cctaagacag
     8941 cactccttgc ctgcggcgac agaggacctg gggccttagc agatattgat gatatggtta
     9001 cagcaattag tcagcagcta gcaagatagc tggtcaccga ttagcaattg ctgtattata
     9061 atataaaaat ttaatggaga atgcaatgaa tcataacaaa tcttctgaaa tctctcgtat
     9121 tgccatcttt tttgcagtca tgctggttat tcacttcatt agtagctggt ttttttatat
     9181 ctggcctgtc ccaattaaac caacactcgt ccatattcca gttattgttg cttctatcat
     9241 gtatggtccg cgcactggag ctatcttagg aggcttgatg gggattgtca gtgtgatcac
     9301 aaataccttg gttttacttc caacaagcca tcttttctca ccatttgtca caaatggtaa
     9361 tctggcttcc ttgatgatcg ctatgctgcc tcgtatcctg attgggatca ctccttatta
     9421 ctgttataag cttatcaaaa acgagcttgg gcttgtccta gctggtcttg ttggctcgct
     9481 gacaaacacc atttttgttc tctcaggaat atttatcttt ttcccaacag cctctggtga
     9541 caatgtcaaa acgtttctaa ctaccattgt atctggcaat gctattactg aaatgattgt
     9601 ttcagctatc gttaccatta ctcttatccc agctttatcc aagctcaaaa aatcataata
     9661 ttgctcaagc tatgaagcat gctgtctgat aaggatagca tgctttaatg atatgtgaca
     9721 agcaaggaaa ttgatcctta tgtgaaaaaa tgattggaag ctattacaga aaataagtga
     9781 tttttccttt tcaacatgat ataatcccga ctttatcact taaaaacaag taaagaccag
     9841 ctaacccctt gtgtcccaag ggattttgct ggtctttaaa tttattttag tgttgtatat
     9901 ggatttttag cgtaatgttt gagctcttca aacttaacga ttcccttcgc ccattcaatt
     9961 cctagcagtc tgtttaactc
//
LOCUS       DARYLJ010000062         9605 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYLJ010000062 DARYLJ010000000
VERSION     DARYLJ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9605
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            26..313
                     /locus_tag="TU746_001744"
     CDS             26..313
                     /locus_tag="TU746_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001256672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892056.1"
                     /translation="MEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQKNGKFYVEGRDE
                     RSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPSPLWNE"
     gene            572..1201
                     /locus_tag="TU746_001745"
     CDS             572..1201
                     /locus_tag="TU746_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892057.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            1183..1605
                     /locus_tag="TU746_001746"
     CDS             1183..1605
                     /locus_tag="TU746_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892058.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            1864..2268
                     /locus_tag="TU746_001747"
     CDS             1864..2268
                     /locus_tag="TU746_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892059.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
     gene            2265..2693
                     /locus_tag="TU746_001748"
     CDS             2265..2693
                     /locus_tag="TU746_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892060.1"
                     /translation="MSEEQYLPVKESLGYRNLKIALMNVFSIDLDKFTIIEGEFENFG
                     FHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDT
                     EKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            2686..3099
                     /locus_tag="TU746_001749"
     CDS             2686..3099
                     /locus_tag="TU746_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892061.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            3362..3754
                     /locus_tag="TU746_001750"
     CDS             3362..3754
                     /locus_tag="TU746_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL0892062.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            3755..4078
                     /locus_tag="TU746_001751"
     CDS             3755..4078
                     /locus_tag="TU746_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892063.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            4391..4861
                     /locus_tag="TU746_001752"
     CDS             4391..4861
                     /locus_tag="TU746_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL0892064.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            4845..5938
                     /locus_tag="TU746_001753"
                     /pseudo
     CDS             4845..5938
                     /locus_tag="TU746_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(6232..9378)
                     /locus_tag="TU746_001754"
     CDS             complement(6232..9378)
                     /locus_tag="TU746_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892065.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
BASE COUNT         2973 a         1666 c         2074 g         2892 t
ORIGIN      
        1 aaatatattg aattggaaaa aagatattga agaagcaatt aaaaatcgag gttttgagag
       61 tttacattat gttttatttg atgaagaaaa gcgacttcct tgggcatttc atctttatca
      121 aaaaaatgga aaattctatg ttgaaggaag agatgagcga tcatatatca ttggtcatag
      181 cagggaatat cgtaaatttg atgatgccaa gcatgaattg cttaaaaaat tagaattagt
      241 tatagaatct aatcggttaa aaaagcagtt aggtgaacct acagaatatc cctcaccact
      301 atggaatgaa tgagtttcat gtattgtatg ccatggcacc aagcttttag gaggcagcga
      361 gcaagacgcc caaagagcaa cattagttgg gaatatccta ggaggacttg ccgcctcaag
      421 cgccgctaga aggttcagct tgaatgagcc aatagcaact agggtgacga aaccgaccca
      481 caaccgccag cagcttttga agaaccttga gaacagcaga ctggcaagag aaagctcaag
      541 gtttaagaat tatgtagcaa gagaaaaatt catgacaacc cttgcaggca tgagtcctga
      601 ggatagtcag cgctatattc aatggcacaa atacgcaaag gctggactta gtccgtcaga
      661 tcgagtaagg attctagaaa tatctgagaa ggcaccgaag atagagtatc ttccgggaaa
      721 aacatcagat agtatattgg caatatccaa gggtgatcgt ccaaatgtgg agaaagtcta
      781 cagtccagat tatattggat ttcatagaaa acaatttgat aacggtgcaa ctagatttca
      841 gaaatttaag cccaatgtag attaccaaga cggtttagtt ggtgacgatt taggcaatag
      901 tttttggtta agtaccaagg acgcggatat tatccaggag ataggaaagg gaaataaccg
      961 tctttatgag acactcttag gctttgatga agggtattta gaagatggtc ccctctatcg
     1021 cttagatgtt tcaccagaag ttgtttcaca aaaaggtgtt tcaataccaa gtggtaatga
     1081 aaaaggggca aatagctggt ggcgtcctgg aggtcgtact tatccgggga atataccaga
     1141 gggagttatg caaggtatca gtacaaagaa aggagatcac acatggcacg cagtcaatta
     1201 gagtgggaag atgttagtca atatgaggag gtaaagggct atggtcaaag ggtgtggaag
     1261 catcaaggga aatattactt tgttgccgaa gaaggtggca ttgctgttca acgagtagta
     1321 tatgagttac cgtatgactt atttgaattg ttggaaagtg gagaacgtag tcttggagat
     1381 gttcattcaa agctacaaga tggtaattgg ccaccaacag aagaggaaaa gaagcaaagt
     1441 catagaaaat ttgttattga cacaccaact gcgctgattg cagaccctac tagtgtgtct
     1501 ctgttctcag aagaagaatt atcaaaatta gtgccaatcg ctgaacaaca gtggatagat
     1561 tggaagggaa agctgccaga tgattatgtc agtcctttga aataatgttt aagatagcgg
     1621 agccgagatt agctctgcta ttttaaagca tgttcttaat aattagcctg cgacagctta
     1681 tcagggagta gctcgtcacc ttgaagccaa tgccaagcgt ctccaagcgc cgccagaagg
     1741 ttcagcttga atgagccgat agcagctaaa gtgacgaaat cagcgaaaat aaccctttct
     1801 gaaaaggtac tagacacaaa ggttcggttt gatgagtctc gcattgtggc ttacgcagaa
     1861 agtatgagta agaactatac agaagctgac gtggccaaat taaccgagct gaccacccac
     1921 aatgcaaaaa ccaaaacagc tttgctggga tattacgaag caaacagcgt tacttcgtat
     1981 gaacaaattg cacatcaaaa taagttaact tactttgatg ccggaagtga tggttggaat
     2041 gcgatgtcga gagtggattc taagctagct caaagggtta atcgtgaatt tttgataaaa
     2101 caaattgaga aaagaaaaac atttatatta acgtctaatc catatactgc tcaatcaatc
     2161 gcagatgtta gtggtatcgg gaagtcttat gctaaagaaa ttcagatttt agcagaaaat
     2221 ggatataata ttgaaaaatt tgaaaggttt tggagggcat ataaatgagt gaagaacagt
     2281 atttaccagt aaaggaaagc ttaggatatc gtaacttaaa aatagcttta atgaatgttt
     2341 tttcaataga tttggataag tttacaatta ttgaaggaga atttgaaaat tttggttttc
     2401 atttaaatta taacaataaa gaaatcataa tctggattac atcaactggt aagaatagac
     2461 aatttgaata tggagaagga ggacaattga tgatttcact tcctaatcca aagtatcctg
     2521 atagatcctt tcttgatagg gtaaccttag aaagtctttt aacagacacc gaaaaaatag
     2581 aagcagttga ctatgctttt ggaagatacg agcatcgtct cgaaatagcg ttggccattc
     2641 taaaagatta tttagattca gacgaagcaa aggttttatt gaaaaatgag tgagcaatat
     2701 ttatcaataa aagaaagctt aggttataag aacgttaaac aggctttatg gactattttt
     2761 tcagccaacc ttgatgaaat ttctatacat gaaggagaag atgagaattt taactttgtc
     2821 tttacatata aaaattgtga aatgatgatg ggaatttatg atactggtaa gaatattcaa
     2881 ttccaagctg gagaaggtgg tttattcagt gtaagtttac ctaatcctaa atatccggag
     2941 cagtcatttc aaaaaattgt atcactttct tatttaattt ctgataaaaa tgtaagtgaa
     3001 aatataagat ggtgcttagg actggatctg aaatctgttg aatatgttat gcgtgttttg
     3061 aaggattatc tggatcaaaa atgtgaagag gaacaataat tctaatcact tctggagggc
     3121 atatagatga gtgaagaaca gtatttacca ataccttcga agagaatacc agttaaaggg
     3181 aaggtatttt gcagaaagaa tcaccatgcc agatggaaaa tatgcttatc tgtccaatga
     3241 cattgataaa gctaccggaa caccaattcc tgtccgatat agaaattacc ttaaggctga
     3301 tggttctatt aattggccaa actataatgg ctttagtctt gatgtaaagg gaaggcctat
     3361 catgactcca gctttcctaa aaacaggtga tttacttgat agatatggag aatctggagg
     3421 aacattcaca agtccaatcg ttgaccgtaa ggttatacca tttaacaagc gaggcttacc
     3481 atacccagag gactatcaaa attatcatca atataaggtt cttaaggata ttaatatgga
     3541 aaatgttgaa aagggttacc ataatttatc tgatagtaga aaaaaagagt taaatctatt
     3601 aatgaataga tttgattttt cactggtaga catagcaact ccacaaaaag gaatgattga
     3661 tcttgtcttt ggctctggtg gaggtatcca aataaagtta ggaacttctg taagttggta
     3721 tgaaaaattg ggtttaatta aggagataaa gtagatgaaa aatttagatc atcaaaaggc
     3781 agaactatta gaagcagtcc atcaattagg ttatgatagt ctaaggtatt ccattttttc
     3841 taaagagaga ccaggagaat gggaaactgt cattgaatat gataatagtc aaggcttata
     3901 tgttgtgtat gcaactatgg atagagctag ttataataag aaattaacat ttgaaacatt
     3961 tcaagaggct aaagaaaaat ttcttgaaaa acttcggtta gatatccaaa tcaacaggta
     4021 ctatgtggaa gagggcatgc ctgtaaatta cgattctcct ttgtggtcaa aaaattaata
     4081 caagtaaagg agaatataca tggcatgtag tcaattagag tgggaagata aatgaaataa
     4141 tggtcctagg aaatgtcccg actggaaact atcttatgaa ctcttttatg gaaaagtgtt
     4201 gcacttaatt tgaattttgt catataaaaa agccctataa tctccatggt ggacttaccc
     4261 actacagaaa tgatagagct aaaaatctcc atttggggat ttttttgtaa ccaaatgaag
     4321 cagtcgttcg ttatataggt gaagaaggga ggggagaatt atcaggctag atgcttatga
     4381 aagagagcta gtggcttatt ctaaggaaat tattgcctac ctagtgagat caggtgttgc
     4441 taaggagcta gcgcgtgata ttagtcaaga cgttttgtta aaaatgcttg agagtgacct
     4501 tgctctgcct cctgaaaaaa tacgtgcctg gatgtatcgg gttgctgtta gaaaatacat
     4561 tgaccgatat aggcgggata aggcttactt ggatattctc caaagggatt tttttcatca
     4621 agaaagggtt gttgaatttg accaccccaa ttatgagccg ctttatacag cagtcaatga
     4681 attgccagaa aaataccgct gggtcttgtc gttttattac tttcaggacc tatcagtcaa
     4741 ggaaatggcg tctctgctcc attggtcagt tagcagcgtc aaggtcaact tgatgcgggg
     4801 aagacgatgc cttaaagaaa aactaaagaa agcaggttat acctatgacg atttcaactg
     4861 attttgaagc cattgctaag cgccataaaa ggaggctgac ccttaaatat gtagtgctga
     4921 gtgctggctt agccttagta gctcttgtac tgggctatat gggattaaat cgattgacaa
     4981 gcatgaacgg tcagtattta atggcttatt acaacaatcg tatacaaatt gcttatccca
     5041 atattgatgt taatagcttc ttttacaatg ccaattcgca gtttactggt gagcttcatt
     5101 ctgagcggac caaggatatt gctgggattt cggtaccgtt tgagccctat agagctcctt
     5161 attccttgcc tttacccaga gagagatgga ctataccaat gaataccttg tttcaggtga
     5221 tgatggacgg tcaacctaca caagaggtac acattataaa atgcctcgct tcttcaacac
     5281 taaggccaag atcacagaaa gcaactatga caagccaacg caggacctag actttattgc
     5341 tgacatgtca ggacaggcga ttgaggtagc cattaccttt gataagcctt atttattatc
     5401 ggacatagtc aagctggttc cagaccagct aaagctgaat tggatctgga ttggcacaga
     5461 aagcagctat gacacctcag ggcttttccc tgctaattta tatggcttta agccaaactg
     5521 gaaggctaat atgacgtaca aggagcaaaa gcagttagat aaaaaaataa acgatatcct
     5581 aaaaaaggac agcgaggctg atttgtctaa gcttaatgct gcttacgata agccagtcag
     5641 tccaacggtg gctctgcaaa attcctatga taccttcagg cactatctac aagaggcagc
     5701 tgacaatcat tggattaata gtacctatgg cggcgctaat ggatctcatt taagtgagca
     5761 ggaggatgtg gccttatttc taaaaaacaa tcgcaatgtc aaaacagcta agtttgctgg
     5821 cattatttta accggcaagg ctgagcagtt tgcctcctta aaaacagctg attggattta
     5881 tgcctcaaat attggtcagt ctgttgccat tcagccctat catcagctaa ccaagtaaat
     5941 aaaaagcttg tgctgctaat caagcgcatc aggcaaagga taaaaagcct aaaagagatt
     6001 agattaagta aatcgatgct taaaaaagct ccagcttagg tcaaaagacg tcaaaaggct
     6061 cttggaggtc agtgtttgat cactgcttct ggggcttttt gctttgctgc aatcaaaaaa
     6121 gcttgaagca gctctctcaa ttgagcatgt ccttcaagct gagactctta tattttatag
     6181 tatttgtaag tatagtttta gctagccttc ttttaagccc aagggcttag cttactgttt
     6241 agtatctttt tctaaattat tgataataac tggataatcc ttcaatgcag acttcatgtc
     6301 atttagagtg ctttgatatg ctgtttggtc tgaggctacc aatgctagct tgtcattcca
     6361 tgctttatag tttaatggct ctgcctttag agcagcatct aaatgattaa gcttagtctc
     6421 cttgtcagta gctgcttcag ccttatatcg ttcatattct gaggcattat aagcgtctat
     6481 attaagagag tagacgttat gaatttggac ataaggaagt gttgtgttgt agttaccaca
     6541 gcctgtccag cctgagacat catagccgag ctgataggta tggtcagcat ttaagtagat
     6601 ataagcacag tgacctggtt gtccaatagg aaaggctggt acaccataag cctgtgctag
     6661 cacactactt aatttagaca tagcaccgca gacaccacca tatttgatga cttccttgat
     6721 ggttggattt ggtccgtaaa agccagagct ttggacgctc acacctgttt ctgggttggt
     6781 catgacatag ctgatcagtg aatagccctt agtaatatca ttacggttaa tcatagcagg
     6841 cttattggtt tcaacgtatt gtcttaacca tttcatgtcc tcatcagtaa ttttagcatt
     6901 gacgacattt cggatttgct caacagttaa gctgtaaaaa tcttcaaata ggatattgcc
     6961 ctgctcagcc tctgcaaagg ttgcaaatct ttcaagtgga tcaatcttgc ggctttcatt
     7021 gtaccaagca cctacaggct tgttaaattc caaggcaacc gcaatggcca ttttgagctg
     7081 aataccttga tgtgaggttt cgtatttatc ccaaatctta aaccacaatt ccaatgcttc
     7141 tagctcattg gtgaggttat aggtgttttt gaattggtat gatgacatgc caccctgtgc
     7201 tgcagaatgg gcatagcctg caccaagata taattgcatt gcttcattat ctttgagcaa
     7261 ccaatcaata aaggctttat gcttgtcgtc ttgcttcttg aagtcctcga ttttttcctt
     7321 ggttagtctt ttttcaacgg cttgtacgag tgtattagta gctttagcct ctagtgcaaa
     7381 tacagaagcc aaaccaccct tggtgattcg aatctctgcc ttatttttag ggaggctaag
     7441 agaaacagcc ttgttttctt catcataggc tttgactcta gtatggtgct cactaccagt
     7501 taggcggatc ttgtagccca ccttgaaggg aatagtctct gttttggctg ttagagcttg
     7561 gtttccaata aagtcttgtg tgtagacaac cttgtctttt aggtctaaga cctcaagctt
     7621 ttcgtaagtc ccactgaagt aaacatgtgg cttagccttt ttggttttga gagttaaggt
     7681 agaggcattg tagtcaacct ttaaggttgc gtattctgca ttgcctaagc caaggaagcg
     7741 cagcgttcta ttactatcat caatacgctc aagctgcccg tttctcacca cataagtgta
     7801 agggttggta ttgttttgct ttagagcgtc attgtggtta gtgtagaagc ggttaggctc
     7861 ctgcttagtg atgactaggt aatagccttc cttgagagta aggctttctg ttttagctgt
     7921 ttgggaaaca ttacccacgt attccttagc ataaacggtt tcttttttct cattgagaat
     7981 ggttagggta gcgtaattgt tagcgatgta agagtgaggc tgtccttttt tagtgactaa
     8041 gcttgcagtg taactgccgt cagcatagaa gtagagctga gcaaatatac catttcctag
     8101 cccttgtaga gtaaattgct gtagcaggct agctgcctta tcaagtaaac ttaggatttg
     8161 ctctttttca ggctctgttg agtcagtcgc ctttttccta agagcatcta ttttttcttg
     8221 tgtgacacca cttgctagct tacttgtaga ctcatctgta aatagagtca gtacctcaga
     8281 ctcaagctct gagcctgttt tagacctcat tagctctagt gagtggtcaa gaagctttaa
     8341 ggttgcttga tttttagaga gtgttaatgg cgcttctacc gcataatcat cgtagaattt
     8401 cactctggta tggtgctcac tacctgtcaa gcggatcttg tagcctactt taaaaggaat
     8461 agtctctgtt ttagcttcga ggacttgagt tccaataaag tcctttgtgt agattacttg
     8521 attttctgta tccagcacct caagcttttc ataagatcca ctgaagtaaa catgtggctt
     8581 ggtctgcttg gttttgaggg ttagggtaga ggcattgtaa tcaaccctta aggttgcata
     8641 ctctgcattg cctaagccaa ggaagcgcag cgttctatta ctatcatcaa tacgctcaag
     8701 ctgcccatct ctcaccacat aagtataagg gttggtattg ttttgcttta gagcgtcatt
     8761 atggttagtg tagaagcggt taggctcctg tttattgatg atgaggtaat agccttcttt
     8821 tagctcaagc tcttctgttt gtgctacctg agaaacattg ccggcgtatt cttttgaata
     8881 gacggtttcc ttcttgttat taagaatggt tatcgtagcg taattagtag agaaataaga
     8941 gtgaggctgg ccccttttag tgaccaaact tgcagtgtag ctgccatcag catagaagta
     9001 aagttgagca aagacaccat tgcctaaccc ttgtagggta aactgctgta ataggctagc
     9061 tgccttatct agtagaccta ggatttgctc tttttcaggc tctgttgagt cagtcgcctt
     9121 ttgctttaag gtatctattt tttcttgtgt gacaccactt gccagcttac tgcaggagtt
     9181 atctgtaaat aaggcttggg tatcagtcat cagttgtgat agcttagcct cggcagaagg
     9241 agcagctgta tcacctgcat taactgtagc ggctattcca tcagaagtat cagtagttgc
     9301 ataaacaatt gctggagaga gctgatgtaa tgttaatatt ccaacacatg ctagtgctat
     9361 tattttcttt agtttcatcg ttataaagtc cttttacaat aaaataaagt gattcaaaac
     9421 tctgggaaaa gaatagctag ccttaaaact atactcgcaa atactataaa atagaaagac
     9481 tatttaccct ccttagctct tgatgctgtg gtgatgatat tgttacggtg ctaaaaatcc
     9541 tatccctcct ttttgactat tttgtctctc ttattccata atattaaaaa atcagaatat
     9601 gtcaa
//
LOCUS       DARYLJ010000063         9382 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYLJ010000063 DARYLJ010000000
VERSION     DARYLJ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9382
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(7..369)
                     /locus_tag="TU746_001755"
     CDS             complement(7..369)
                     /locus_tag="TU746_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL0892066.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TU746_001756"
     CDS             complement(347..781)
                     /locus_tag="TU746_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL0892067.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TU746_001757"
     CDS             complement(768..1058)
                     /locus_tag="TU746_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL0892068.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TU746_001758"
     CDS             complement(1015..1440)
                     /locus_tag="TU746_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL0892069.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TU746_001759"
     CDS             complement(1418..1741)
                     /locus_tag="TU746_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL0892070.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TU746_001760"
     CDS             complement(1742..2728)
                     /locus_tag="TU746_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL0892071.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TU746_001761"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TU746_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL0892072.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TU746_001762"
     CDS             complement(3829..4476)
                     /locus_tag="TU746_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892073.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TU746_001763"
     CDS             complement(4478..6481)
                     /locus_tag="TU746_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL0892074.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(7018..7383)
                     /locus_tag="TU746_001764"
     CDS             complement(7018..7383)
                     /locus_tag="TU746_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL0892075.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(7444..8490)
                     /locus_tag="TU746_001765"
     CDS             complement(7444..8490)
                     /locus_tag="TU746_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL0892076.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
     gene            complement(9054..>9382)
                     /locus_tag="TU746_001766"
     CDS             complement(9054..>9382)
                     /locus_tag="TU746_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892077.1"
                     /translation="EAIFTENSVTIRDIFSPRSFTGVNKIVFTWKGYDLYLDSTNANR
                     LSALGWGSTALSGLIPDPIVSKVLAAALGVVSASISYANAAGRGVIVAFVGTFPRGVI
                     HWVASQ"
BASE COUNT         2966 a         2125 c         1710 g         2581 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta atccattttt ataaaaaaat aacattatat
     6841 catgcctcaa atgattttat cataatgagg ctcgctatgt tgttttctct atcccaatca
     6901 ggcactgcta gattagacat ctttccagac aacaaaaata gcctaaggtc agctctctaa
     6961 ttagctgatc ttaggctatt tgagtgataa tagatttgac tgatagctgt aagcctctca
     7021 gatgcttaat ttacagctaa gggaggcttg tgggcagtca tttctttgct caaaatatga
     7081 ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag agtgatactg
     7141 ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc aaaaggtagc
     7201 caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct gccattcttc
     7261 ctcaaaataa gccagtgcag caggccagct gtcaaacgat ttctcctgaa caatatcgtc
     7321 ttgccaacca tctataaacc accaaggctc ccagtctcca tacatttcaa tcacttgata
     7381 catgttctca tttcctctat tgcctattat agccgaagaa agatattttt aaaaaacatc
     7441 tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca gcagcataag
     7501 ggcctctgag caaagatgag tagctagcag ggtcatgaga aagaccagtt tcccttttgt
     7561 ggccggggca agctggtagg gccttagcag aaatagcgaa cattcgataa acattgggtg
     7621 caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt tagacagaag
     7681 gctgatacgg acactggcat tgaataaaaa ggtagtaaac agcgcagaaa gcaagaagaa
     7741 atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggcca ataagatcag
     7801 gcaaacagcc gcctttctca tatacctctg agaaaaaagc gacgatgaaa agtgatcata
     7861 gagcaagcag cccgcacaaa gataagcagg ggtgtaaaaa ataccattgc gacttgtttg
     7921 aaaaatgtgc atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta aaaaatgaga
     7981 ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg ttaccttctt
     8041 accaaaggtc ttcagagaaa gctgaacaag cacccacccc agccataaag caggaatata
     8101 ccacagatga tagcacatcc caaaataact aagggctaaa cacaagccaa ggggaagata
     8161 atgcttaggc agacgaagcg actcaaaaaa ggcataagca taagggaggt aaatcagaga
     8221 ccaaagcaaa taggttttta gtatttgctt gaagtactgc ttttcccgat tcgcctctct
     8281 aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg ccattcttcc
     8341 taaaaagctt ttcaaaaaga aatgcagcgg ctcatactga aacagcctac cgctatgaat
     8401 aacaataacc attatggcaa aacagtattg taacaggctt accacagagg tattgaggct
     8461 gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt aagagattaa
     8521 tatacgtata acttttagta tttatcgcat ttgtctctca ttttgattaa tattgttttt
     8581 atcatagcgt aatataacca attaatctaa tgattttagc ataacaaaag gagctaaggc
     8641 tagctcctga acatcacaaa agagcagacg aacttcatct cctctcgtgc ttagatataa
     8701 gccacccact acagttaaca tggagccata aaacgaagga attaactcct tcgttttctt
     8761 tcaatttttc ttggaatatt tttatagact tttcttacgg atatagtaag aataactacc
     8821 agcaataatg acataattca ataaaagaca taattaatca caacttgatt gtctttctaa
     8881 caaatccatt ccctgcctgg atcattagta tacgaaaaaa atgataggta aaactatacc
     8941 caataggcag aaaaaaactt tccaaaaaat agtattattt ttaaataatt tatcaacaaa
     9001 caccaataat atcaaattaa ttgctaaaca cagtattttt aaatataatg ctatcattgt
     9061 gaagccaccc aatgtatcac acctcttgga aaagttccta caaaggcaac aattactcct
     9121 cttcctgcag cattagcata agatattgat gcagacacaa ctcctaaagc ggctgcaagt
     9181 accttagata ctatagggtc tggaataaga cctgacaaag cagttgatcc ccagcctagt
     9241 gcagataatc tattcgcatt ggtactatct aaataaagat catagccttt ccaagtaaaa
     9301 acaattttat ttaccccagt aaatgatcta ggactaaata tatctcttat agtaacagaa
     9361 ttttcagtaa aaattgcttc tt
//
LOCUS       DARYLJ010000064         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYLJ010000064 DARYLJ010000000
VERSION     DARYLJ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            101..1027
                     /locus_tag="TU746_001767"
     CDS             101..1027
                     /locus_tag="TU746_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL0892078.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TU746_001768"
     CDS             1135..2421
                     /locus_tag="TU746_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL0892079.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TU746_001769"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TU746_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TU746_001770"
     CDS             2977..3189
                     /locus_tag="TU746_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL0892080.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TU746_001771"
     CDS             complement(4085..4225)
                     /locus_tag="TU746_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892081.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TU746_001772"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TU746_001772"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL0892082.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TU746_001773"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TU746_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TU746_001774"
     CDS             8213..9118
                     /locus_tag="TU746_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0892083.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1729 c         2097 g         2811 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagtctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYLJ010000065         9141 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYLJ010000065 DARYLJ010000000
VERSION     DARYLJ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9141
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            4..594
                     /locus_tag="TU746_001775"
     CDS             4..594
                     /locus_tag="TU746_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0892084.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            604..2166
                     /locus_tag="TU746_001776"
     CDS             604..2166
                     /locus_tag="TU746_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892085.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHQID
                     DTFIYDGDIDLS"
     gene            2549..3650
                     /gene="prfB"
                     /locus_tag="TU746_001777"
     CDS             join(2549..2620,2622..3650)
                     /gene="prfB"
                     /locus_tag="TU746_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL0892086.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3701..4393
                     /gene="ftsE"
                     /locus_tag="TU746_001778"
     CDS             3701..4393
                     /gene="ftsE"
                     /locus_tag="TU746_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL0892087.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4386..5315
                     /locus_tag="TU746_001779"
     CDS             4386..5315
                     /locus_tag="TU746_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0892088.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5705..6346)
                     /locus_tag="TU746_001780"
     CDS             complement(5705..6346)
                     /locus_tag="TU746_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0892089.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6683..>9141
                     /locus_tag="TU746_001781"
     CDS             6683..>9141
                     /locus_tag="TU746_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL0892090.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIG"
BASE COUNT         2584 a         1815 c         2100 g         2642 t
ORIGIN      
        1 gctttggaag ggatcacaaa gtcctatggc gccaagctga tccttaagga tttttcctat
       61 acctttgaac aggggaaaaa atatttgata aagggtgcca gtggtagagg taagtcgact
      121 ctgttacaca ttattaaggg aactgctgtt gactcaggta aaatagcgtt tatcaccaaa
      181 gacaatcact catttgaaag ctatcaagct aacattggca tggtgagtca ggcacctttt
      241 ctctttaatg gcaccttgga agagaatatc tgtctgaatc aggagttttc caaggagaat
      301 atccttgctg tcttggacca agttcacctg ttggaggaat taccagctgg tctaggcttt
      361 cagatagaaa ataatgggac caacatttcg ggcggccagc gagtgcgcat agaattggct
      421 cgatttttgc tacgtcagaa ggatatttta ttgcttgatg aggtcacagc agccttggac
      481 aaggacaatg ctcggcgagt aagggagctg attttttctc ttcctattac catcattgag
      541 gtggctcatc atgtggatca agctatagct tatgatgata tgatagaatt gtaggtgatt
      601 aagatgttta agtattttaa taaatatcta gtgacactaa cgcttgttgc atgtgcctta
      661 aacagtcttg tctttctgat tgaacccttg atcactagta agatttttga tttaacgttc
      721 ttaaataatc atcaagacac cttgtccttt ttaggctatg gtctgacctt atacgtggtc
      781 ttatattctg ttatgttcat tgctaatctt ctgatcaacc atatcatgac gattgggtgt
      841 ggtagaatca ggttgcgtct ctatcagaat ttaatcttaa attatcggga gatgagtcat
      901 gacaagaaaa tttctatgct gactcaagat gtagaatatt atctatggaa tcacatcagc
      961 cctagcattc ttctcgtatc acacgtgagt aatgtccttt tgctcagtgc ttacctgtta
     1021 tcaaaaaaca tgctaattgg tcttattttt attgcatgtg cttttgtatt tttagtggtt
     1081 cagcatgtga ttggtcaaaa ggcagagcaa aaaggtagtg agctggcagt agcgagacaa
     1141 aagctgcttg gcttattaag tgatgtggtt gcggggcatt cgacattaat tcaaaatcaa
     1201 gctctttttg ctagcctcaa acaggtaaaa aaacagtcag agcattatga gagctcacgt
     1261 caagcatttg agatatttag gtctttcttt accctattgg cacatctgat gctgtttatt
     1321 tctcaattct tgcccatttt tttaggctta gccttaacct tattaggtgt taagctgaga
     1381 acaactgatc ttattgccat gtttattgca gcaacgcgct tagaacagcc actcaaaaat
     1441 attgttgatg atatgtttag gcttaatggt gcaaaagcca ttgctaagca ttttgagaca
     1501 cttttagagc agcctattcc aaaataccag tcgcatgcta tgacaggtga tccttttgaa
     1561 tgcttagatg gtcatcatct ggcgaaatca tttgcaggta ggaccttatt ttccgatctc
     1621 tcttttcatt ttgagaaggg aaagaaatac ctgattaagg gatcaagtgg atctggtaaa
     1681 tccacactct ttaagcttat cttacaggag atgagtcctg atgaggggac actagatatg
     1741 gtattgactg gaggtcagac gactgataat tatcaccatc gcatagggct gattgcgcag
     1801 tcgccttatc tttttaacga tagcattcgg tataatttga ccttggggga ggcgttttct
     1861 gatgagttgc ttttagaaaa gctagaacag gttggcttga ctgatgaatt tgacgatatt
     1921 ttaaaccacc aaattgttaa taacggagaa aatatctcag gtggtcaaaa gacacgtctt
     1981 gaaatcgcaa gaagcctcat tagacaaaaa gatgttcttc tagcagatga agtgacggct
     2041 ccacttgatg tcaaaaatgc taaaactatc cgacagctac tatttagttt accggtaaca
     2101 gttattgaaa ttgctcatca gattgatgac acctttatct atgacggtga tattgattta
     2161 tcgtagaaaa tatcatcaca ttgcttagaa ataataattg atgcttatga aattgtcatt
     2221 cacacagtga atggcttttt cttaggctaa attttccatg tggagcttga tctgataggc
     2281 tatctgagaa aaaaagctaa caacagccat gttttttggg gctatgactg ttctaatacg
     2341 agctgcctct agctgctggt atataagagg tgacatgatt gtcacaattc gtcatcattt
     2401 tgtcgttaaa tttttacata gatttcttat gctagtcatg gcagagctcc ttaccctaaa
     2461 aagaagggaa tttagctgat gggaaatagc aattctaaag cctttatgat aaaatgaaaa
     2521 aagacactat aatagaagag gtaactgtat ggaagtggca gaaatgcgcc agcaaatagt
     2581 agaaaacaaa gagaagttga ctagcttcag gaggtctctt tgacttagag cgtttggagg
     2641 aggatatagc tctcttagaa aataagatga cagagcctga tttttggaat gataatatgg
     2701 cagctcaaaa aacctctcag gaattaaacg agctcaagct cacctatcaa acctttcatg
     2761 atatgcagga gctatctgat gagacagagc tttatttaga aatgcttgac gaggacgata
     2821 gcgtcaagga agagctagaa gcaagcctga ttaagctcag ccagatgcta gcaagctatg
     2881 aaatgacgct gcttttgtct gagccctatg atcatagcaa tgcaatccta gaaattcacc
     2941 caggttcagg tggcactgaa gcacaagact gggcagacat gctttttcgc atgtacactc
     3001 gctttggaaa tgccaagggc tttaaggtag aaactctgga ctatcaagca ggagacgagg
     3061 caggaattaa gtctgtgacc ctttctattg aagggccaaa tgcttatggc ttcttaaaat
     3121 cagaaatggg agtacatcgt ctggtgcgta tttctccttt tgactctgct aagcgtcgtc
     3181 acacctcctt tgtttcagtt gaagtcatgc cagagcttga tgataccatc gaggtggaga
     3241 tacgtgatga tgacattaag atggacacct tccgctcagg tggtgctggt gggcaaaatg
     3301 tcaacaaggt ctcaactggg gtacgcttga cccatatccc aacaggaatc gtagtggcgt
     3361 caacagttga ccgcacccaa tatggcaacc gtgatcgcgc tatgaaaatg cttcaagcca
     3421 agctttatca gttagagcag gagaaaaagg cagaagaggt caatgccctc aagggggata
     3481 aaaaggagat cacctggggc agtcagatca ggtcctatgt ctttacgcct tatacgatgg
     3541 tgaaggatca tcgtaccaat tttgaggtgg ctcaggttga taaggtgatg gacggagata
     3601 ttgagggttt tattgacgct tatctcaaat ggcgcatggg tgaggattaa agtgatcccc
     3661 actcagataa acactaacag cttagagaag gaagaataag atggcattaa ttgaaatgaa
     3721 gggtgtttct aagaaatacc gtcgctcgac aacagctctg agagacatta atgtctcagt
     3781 caatcaaggg gaatttgtct atattgttgg tccatcagga gctggtaaat caacctttat
     3841 caagcttctt tatcgcgaag aaaagctaag ctcaggcagc ctaaaggtgg gtgagtttga
     3901 cttaaccaag ctaagaggac gtgaggttcc aattttacgt cgcagcattg gtgttgtttt
     3961 tcaggattat aagttgctcc ctaaaaaaac ggtctttgaa aatgttgcct atgctatgga
     4021 ggttatcgga gagagacgtc gccatatcaa aaagcgtgtt cctgaggttc tagaccttgt
     4081 cgggttaaag cataagatgc gctcctttcc caatcaattg tcaggtggtg agcagcagcg
     4141 tgttgcgatt gcacgcgcta ttgtgaacaa tcccaagctc ctcattgcag atgagcctac
     4201 aggcaatttg gatccggaaa tttcttggga aatcatgcac ctgcttgagc gtatcaatct
     4261 acaggggaca acgatattaa tggcaacgca taacagtcat atcgttaata ctcttcgcca
     4321 tcgcgtggtt gcgattgaaa atgggcgtat tgtccgcgat gaggagaaag gagactatgg
     4381 ttacgatgat tagacatttt ttccgtcata tctgggaatc tatcaaaaat ttaaggcgta
     4441 atctcctcat gacctttgcg tcagtcagta tggtgaccgt caccttaacc ctgcttgggg
     4501 tctttgctgc aaccctgctg aacattcaac gtgtcgcttc tggcgtggaa aacaacattc
     4561 aaatcaatgc ttacttacag gttgattcga cagatgctgc taagatggtt cagtcgatta
     4621 atggagagca gataaataac gagaattacc ataagattta tgatcagatt gcagggctaa
     4681 agggtgttga gaggattatt ttctcaagca aggacgagca gctgcaaaag ctacaggata
     4741 gtctgggcga tgtctggggc atgtataatg aggatagtaa tcctctgcaa gacatctata
     4801 tcgtagagac caagacccct aagcaggtca aatcagttac caaggccatc aaaaagattc
     4861 aagggattga agatgcggac tatggtggta ttaattctga taagcttttt aagttttcaa
     4921 aactgattca aacatggggg attatcggaa cgctgttgct cctgtttatt gcgatctttc
     4981 tgatttcaaa taccattcgc atgaccatca tgtctcgtca gcgcgatatt gcgatcatgc
     5041 gtctggttgg tgcgaaaaat tcttatattc gtggcccatt cttttttgaa ggggcttggg
     5101 ttggtctgtt tggtgcgata ttgccatcgt tgattattta ttatggctac gagtttgcct
     5161 acaagcattt caccccggaa ttacagcata atagcctgtc tatgtaccct atcaatccat
     5221 atgtttatta tttaattggc atgctttttg tgattggtat tatcattggg tcactaggat
     5281 cagtcttatc tatgagacgt taccttaagt tttaattgaa agagcttcta gcctgtgtgc
     5341 ctggactggt accctgcggt tagggctctt tttgcttttg gggcaatgct tgctagataa
     5401 gcaaacaata gcttaagccc ataccattaa gtattgggct taagctattg ttatagttgt
     5461 ttaggtaata gaagcagccg gaacttgagg tgtcctatct aggtcttgag ctatagcttt
     5521 tctggctagt tggtgtttct tcacgtaaca gcgatttgtc gaacgataag gtgctcttct
     5581 tgtgatagct ggcttgtagt gatcgacagg tgctaagtca aattagccat cctgatggac
     5641 tggagtcata gcttttgctg ctgcgcctgg ttgggcatag actgggcatc tcggtagctt
     5701 gagcttatcg ctgcctcaga aagggattgc tatttttttc atggctaatg gtggtagctg
     5761 agccatgccc cggataaatc tgataatggt taggaagtgt tagcagctta tcacgaatgc
     5821 tagcaagcag ctgttcaaga tttccagtcg gcaaatctgt tctaccgatg ctttctctaa
     5881 acagagcatc gccagtaaac accgcctcct cctgctcaaa gataaaggaa acgccaccgg
     5941 cagagtgtcc tggtgttggc actactgaaa agtgaaatcc agctagctga taaggtgtct
     6001 gatactgaaa gagcttttct gctggtttgc agatgatatc aggcagatca gcgtgacgta
     6061 tcagtcctga caggttcatt tctggtttat aaagccagtc cgcctcctcc ttggcaacat
     6121 agacaggagg gtgctggcag ctctctctca ccagctctag gctcataatg tgatcataat
     6181 gcgtatgggt cagtaggata gcagcaacag gcttgttgat ggcatggatt tgtgataaaa
     6241 tagcctgccc cttgcttcct gggtcaatga ctaaaatagc ctcgtcattg acaagaaggt
     6301 aagtgttttc acccgcaacg ggattcatca gtgtcataat agtcataccc ttagtttacc
     6361 aaaatctgac tcaaaagaca gctcaaaacc acctcttttg ataaaagtga tctgtttaat
     6421 ggttttgatg gctaagccaa gatagctcca gcttaaaggc tgcttttttt aattaatagg
     6481 agcaaaaagg agctgcctca gcgctaacag ctaatcagag tattagctct ctagtgtcat
     6541 agcaaggaag taggctgggg cgattaaaag gcttgataac tagcttttta tgatactgac
     6601 tagccctatt gagctgagct aagactggta ttgtcagatt taggcaaagc ctgtcagaaa
     6661 acgtgctata atagatagta ctatgatcaa tgagttttca caaaaatatg ctgtgattga
     6721 cctggaagcc actagcccag gtccaacagc gtctattatt caggttggca ttgtgatcgt
     6781 tgaaggaaaa gaaatcgttg attcgtatca aactgatatt aatcctcatg agcccttgtc
     6841 agaccatatc aaagcactca caggtattac agaccagcag ctagctcagg caccggattt
     6901 ttcacaggta gcaaggacca tttttgagct gattgaggac tgtgtttttg ttgctcataa
     6961 tgtcaccttt gacgccaatt tgttggcaga agccttattt ttggagggct atgatctcct
     7021 cactcctaga gtggatactg ttgagctggc tcagattttt taccccagcc tagaaaaata
     7081 cagccttagc cacctatcag aggtgctaga cctaaaccta tctgatgctc ataccgctat
     7141 tgctgatgct caggcgactg ctaacttatt tatcaagctg cttcacaaga tagagagctt
     7201 gccaagagaa tgcttggaga ctcttttgct gtatgctgat agtctgttat atgagacagc
     7261 tatgattgtg agacaagccc ttgcagtcag tcggccttat tctacgagtg actacatcaa
     7321 gattaatcag atcttgctaa aaaagccgga tcagctaaca aagccctatc aattatccca
     7381 gtcctttgag attaatgcag ccctcttagg tcttgaggag cgccccaagc agctcagctt
     7441 tgcaaagatt gttgaggaga ctctttttca gaccgagcca gcctttatcg aggctcaggc
     7501 aggcattggt aaaacctatg gctatttact gcctctcctt gcacagaaac atcagaccca
     7561 aatcttggtt agtgtgccaa ccaagctgct acaggaccaa atcatggcta atgaggtgag
     7621 ggctattcag gagcagtttc acatcgattg ccatagtatc aaggggcctg ctaattacat
     7681 caagctagac agctttcaag agagcctcaa tcagcttgat gacaaccgct tggttaatcg
     7741 ctataaaatg caattgctgg tttggctttt ggaaacaagg actggtgatt tagatgaaat
     7801 caagcaaaag caacggtttg cagcttactt tgaccagatc aagcatgatg gcagtatcca
     7861 gcagacctcg cccttttacg cttatgattt ttggcaacaa agctatcaaa gggctaagtc
     7921 agctcgcttg ctgatcacca atcatgccta ttttttacac cggattcagg acgataaggc
     7981 atttgccaag ggtaagattc tagtctttga tgaagctcag gccttaatgc tgcagctaga
     8041 ggagctagct catcagcgac taaatatagc tgatacgctc caagagcttc aagagcagct
     8101 agctgtgcca agcagcttgc ttgagcaacg cttgctagag ggcattgcct ttgagctcaa
     8161 tcagttaagc agtcattatc atcaggagga ggagaagcag caagctcaag cctcacagca
     8221 tttgctgcgg ctccaagagc atgtcaagga gctaggtgct gcagcctctc agagcctcaa
     8281 gcagctgttc aagcagcagg aaatggatta ttgggtgagc agtgagcagc aggctgacaa
     8341 gcgccaaacc tttttaaatg gcagcagcag gacggtcctt cagtttaaag cattgctacc
     8401 ggagattttt aaggcctact ttgtctcagc tactctacag attagcccta gcattagctt
     8461 ggctgattta ttgggctttg acacttattc ttatcatcag ctggctaagg agaaaagcac
     8521 tcagcaattg gttgtcattg accaagacat gcccttgatt aaggacttga ctgacgaggc
     8581 ttacacacag accatagcag caaggctatt agtgcttcat cagcaacagc aggtacctat
     8641 cttagtgctc tttaatgcta aaaagcacat gctcatggtt tctgactatt tagaggctaa
     8701 tcaggtgcag cacttgacac aaggcaaaaa cggtacagcc tatcacatca aaaagcgctt
     8761 tgatcgtggt gagcaatcaa tgctgctggg gcttgcagcc ttttgggagg gagttgactt
     8821 tgttcatgct gatcgcatga tagaggtcat tacccgcctg ccctttgata atccagaaga
     8881 tattgccact caaaaaatgc agcgctacct acaggcagca ggtaagcagc cctttaatga
     8941 ttattttctg ccgatgacga tcttaagatt aaagcaggcg attggtcgaa ccctgcgtcg
     9001 aaaagagcag aaatcagcag ttttgatctt agatcgtcgc attctgacca tgtcctatgg
     9061 tcagaccatt ttgcacagcc tagaagagga atttctgata tcacaacaaa atttccaaga
     9121 tagtctagca gaaataggcg a
//
LOCUS       DARYLJ010000066         8740 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYLJ010000066 DARYLJ010000000
VERSION     DARYLJ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8740
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            71..313
                     /locus_tag="TU746_001782"
     CDS             71..313
                     /locus_tag="TU746_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892091.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(435..1649)
                     /gene="thiI"
                     /locus_tag="TU746_001783"
     CDS             complement(435..1649)
                     /gene="thiI"
                     /locus_tag="TU746_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL0892092.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(1651..2793)
                     /locus_tag="TU746_001784"
     CDS             complement(1651..2793)
                     /locus_tag="TU746_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0892093.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKPAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            3033..3473
                     /locus_tag="TU746_001785"
     CDS             3033..3473
                     /locus_tag="TU746_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892094.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(3543..4895)
                     /gene="gorA"
                     /locus_tag="TU746_001786"
     CDS             complement(3543..4895)
                     /gene="gorA"
                     /locus_tag="TU746_001786"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL0892095.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(5089..5430)
                     /locus_tag="TU746_001787"
     CDS             complement(5089..5430)
                     /locus_tag="TU746_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL0892096.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(5491..6657)
                     /gene="aroC"
                     /locus_tag="TU746_001788"
     CDS             complement(5491..6657)
                     /gene="aroC"
                     /locus_tag="TU746_001788"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL0892097.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(6770..7450)
                     /locus_tag="TU746_001789"
     CDS             complement(6770..7450)
                     /locus_tag="TU746_001789"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL0892098.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(7447..8610)
                     /locus_tag="TU746_001790"
     CDS             complement(7447..8610)
                     /locus_tag="TU746_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL0892099.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         2568 a         2064 c         1629 g         2479 t
ORIGIN      
        1 aatagtttac aatttatggt tgttttcata taattttcat gaaaggaggg aaatatatga
       61 aaaatctata ttgataagtt gtacactatt agccagtctc ttattaactg gctgtcactc
      121 attgtctttg cagctagctg aggctgttca ggaaaagcct attcaagcgg ttacggtaga
      181 ggatttgacc agacatggca ttgccgaatc cttgaaagcc tacctacaga cgatgggctt
      241 aaccaatgaa gaggctatga aacaatacga ggaggtcctt tctgatgaga ttatccagta
      301 ttttagcagc taaataagag aatttgagca aaatcagcta aaaacaaaag ccagagcctt
      361 taataactaa taggtctggc tttttttgac tgtttagata gactgcttat gttgtagggc
      421 taggtgcgca cctcctacaa caattcctca ataagcgttg ataagctgtc agtttcgatt
      481 tcaggagtga tctcagttac tctgatccct gccactgctc gctcgaccaa tccgtcgaca
      541 tcaaagcgag actcatatcg ttcaacattt gctagcttgg gattggtttt gggacgatca
      601 ggagcaaaaa tagtacagca gtcttcaaag ggctgaatgg aaatatcaaa ggtgtcaatt
      661 tgctgagcga tatcaatgat ttctagctta tccattgcca caactggtct gataatcgga
      721 gttgaagtga ctgcattaat agcctgcatg ctctctaagg tctggcttgc aacctgtcct
      781 aagctttcac cgttaataat cactaaagcc tttcgcttct cacgaatagc atctgtgatc
      841 cgcagcatga agcgtctagt aagtgtcatc aaataggctt cgggtgcctt atgcttgatc
      901 tcctcttgaa tctcggtaaa tggaacctcg ataaactgta tattacctcc aaaacgtgtt
      961 aagcgctgcg ttagatcctt ggcttttctt agcgcaccag gactggtata gggtgggctt
     1021 gcaaaatgca ctgcctcaat ctcaacacct cgtttcaggg atagatagcc cgcaaccggt
     1081 gaatcaatac cacctgatag catcagcatt ccctttcctg aagctccaac cggcagccct
     1141 ccagctccct ttatatcttc gtgagacaga taagcagcct catcacgaat ttcgaccttt
     1201 agggtaacat caggattttt catctgtgcc ttgatatgcg gcaaagcctc aaagacggct
     1261 gctcctaagg tgtggttgag gtcgcggcta tctagctcaa actgatggtc actacgcttg
     1321 ctggatattt taaaggttag cccttcgcga tacaaggagc tcataatctc ctgaactgct
     1381 gctatcagta cagggacact tttttcaact ttatagacag gagataagcc ctgaatacca
     1441 aacaccggct ttaaggcttc aatcacagac ctatcatctg caccattaag taaaacatgg
     1501 gtcctgtctc gagttgatct gactgtcacc tcagaatagg cagaaagaac atcttgaata
     1561 ttagctttta gccgattaat aaaccgcata cggttttttc ccttggtcga taactcccca
     1621 tgacgaacca ttatttctga atatttcata ttatctaacc ttttgtgttt tttcataaat
     1681 ctgtttaaaa atcgttaaaa attgctcaac ctgtcccata tcattatcat catctaggct
     1741 gatacggact gctgtttgag ccaatgctgc tggaattccc attgagacta aggttcctgc
     1801 cggctttcca acctttgatg agcaggcact cgttgttgat atataaatct catgcttttc
     1861 aaatgcgtgc acaataacct ctccacgaac gccctttata ccaaaggtca gaatatgagg
     1921 agcaaaatca tctatctcag aaaagagaat ggtatcctca taggcctgca aggcttgata
     1981 aataaccttt ttcatggctg ctatccttgc ttgagatcta tcctgtcttt ctgtgatgat
     2041 ccttaaagcc ttggccatac ttgcaatagc tgccacgttt tcagttgtcg aacgtagctc
     2101 atcttcttga ccgccaccga ccaataaggg agtgattcgc tttcctgatt ttttataaag
     2161 aaagccaaca ccacgaacag catgaaattt atgaccagaa aaagaagcta agtcaacacg
     2221 cgcggttaag taagcctcaa caggaagctt cccaatagcc tgaacagcat cgacatgaaa
     2281 ggtaatggtg ggcttatcag ccaaaagctc tgatatggct gcaatcggct gaattgaccc
     2341 aatctcattg ttaaccgcca taatggaaac taatatggta tcttttcgga ttaaggcagc
     2401 tagctttttg acatcaacaa ctcccttatc tgtgacagga gcataagaca gctcaaagcc
     2461 ttgactttct agccatttgg cgctttctct gacagctggg tgctcaatgg ctgagacaat
     2521 gatgtgctta ccaaagtgag atttttcaaa ggcaatcccc ttgatagccc aattgtcgct
     2581 ttccgttccg ccagaggtaa agaaaatctc tttggcctct acatcaagta aggccgctat
     2641 ttgcctgcgc gaagcctcca atatacgact ggcattggct cctagctgat ggagactaga
     2701 gggattgccg taaatcttac tggccacttc ctgatacgtt ttaagtgcct cttcgtaagg
     2761 cttggtagtg gctgcattat caaaataaat catgtgtcac cttcattttt attcaatact
     2821 ttattgtatc acaaatttga tgaaatgaaa aaatagatct ttttgcagga taggacaact
     2881 ctatcctaga caataaggta aaccgttgac ttgatttttg ttctagatta tactggtaga
     2941 tgatagagct aagtctgaaa tgcctgttag ccattaaaga cctaaagcat ttgactttag
     3001 ctagcctatg actcgttaaa ggagatattc tcatgtcatc acattattca cgtcaacaaa
     3061 agcctaaaaa atcagcaagt attcccacaa agcatattaa aactggcttt accgcccttc
     3121 aaaaaaccat tgccttagtt ggtagtgttc tgagtattgt tgtagcgaca atcactatta
     3181 atcgagctct acaaccatca aatgagcaac ccaaaagcga ttcctctccg tcatcaacat
     3241 caacgattgt gaaaattatt gaaaaggagt cgtcacactc aaataaggaa gagactgaca
     3301 agacagaaac taattctgat tctagcggta ctcaggcgac acatactact cctagctcag
     3361 ctgatcctgc tactaaggat acagaaaaac aacagaatac cgaaacggaa gcaccggctg
     3421 ctaatcaacc cacagctaat gagccagctc ctaacagtac aagcaatcca taacacaaaa
     3481 cacgataaca ggcaattcag ataagctctg aattgtctgc tatcgtgttt tatcatgtgc
     3541 tgttatctca tggtaacaaa ctcttcagca cctgtagggt gaatggcaac agtattgtca
     3601 aaatcagcct tagtagcccc cattttaatg gcaacagcaa agccttgaat catctcatca
     3661 acaccataac caataccatg cagaccaacg atggtctctt cttctcctgc aacgatcaat
     3721 ttcattaggc agggctggcg atgactagta atagctgtat acatggacgt aaattgtgat
     3781 tgatagacac gaacagccgc ttgcccatag gcttgaatag ctgcctcttc tgttaagccg
     3841 atcgagccaa ttggcggatg gctaaagaca actgtcgcaa ccttgttata atcaagcttt
     3901 tcattgggct tattatgaaa caagcgctct gccaagcgac gacctgctgc gacagcgact
     3961 ggggtcaaag caagctttcc attaacatca ccaacagcat agatgccatc aacagatgtg
     4021 ttttcataag cgtcaacagc aatatagccc ttcttatcca gctcaactcc tgtatgctcc
     4081 aagccaaagc ctgtcacatt tggcttgcgg ccaattgccc aaatcacttg gtccacttca
     4141 agcctacgac catcggacaa atgcacttga agagagccat cattagcctt ggtaacctta
     4201 gtaacatcgg cattggtatg cagccttggt ccagatacct tcatctcatc gaccagaacc
     4261 tggataatat cctgatcaaa ggtcctcagt ggcctgtcat agcgaaccag caaatccgtc
     4321 tgagaaccta gggcattgag cactcctgca atctcaacag caatatagcc agcaccgaca
     4381 actgctgttc gttttggaat atcatctaaa gcaaagaaac catctgagct aatccccagc
     4441 tcagctcctt caatgtcagg aaaaataggc tgaccaccag tagcgattaa aatatggggg
     4501 gctgtatagg tcttacctgc aatgtcaacc gtatgctgat caataaatcg tgcataatca
     4561 taaatacgat caaccccgtt atgctcaaag cccttctcat aagaggcatg aatacgatca
     4621 atataggcct gacgattgct ttttaaggtt ttaaaatcaa acctatcctc taacaccgta
     4681 aacccgtaat ccttcgcata ggtatgaatc gtttctgcta cctgtgcgcc ataccacatg
     4741 acctttttag gcacgcagcc caaattaaca caggtccctc caatagcctt gccctcagct
     4801 aataggacct tagcaccgta cattgctgca cgattcgccg aggcaatccc agcgctccca
     4861 ccaccaatca caatataatc atactgaatt gccattaatt taccaccttt actcttaatg
     4921 cttgcctcaa tagatttgtt attaagctat cattattgct ttattttaat ctactgtcat
     4981 ttgactataa cataaaataa cttgtgtctc aaatccctgc tacgacaaaa aaagattgtg
     5041 ataagcatca acaatccttt cttctcttaa tcctaagcca gcttagctct acttggccaa
     5101 atccttcaat ggtgcaaata caatccgttc aatatcatta acatagacgg aaagagcctg
     5161 ctgagcgtta aaataccctt ttaataggtc attggcctca attttttggc tgagagcctg
     5221 aatatctgcc tgctctgtct ctgttggcag ctgaccggtc tgcatgagtc cttgcaattt
     5281 ttcttgcaca gcaacaaact catcaaatag ctgactggca gcctcatctg ccttaatctc
     5341 ttctctggct tccaaggcct tgcgatactc tgggagcgca cgaacagctc gctcaagctt
     5401 attggcataa tcataaatat cttgggacat ctggatctcc ttttatcatt tattatcctt
     5461 atcatatcac aatatcaagc catttgtcgc ttaaaaatga tgaacatagt cacgataggc
     5521 aaaaaaagcc tgctttaaat cggtcatatt gtctgatgga aattgttcca aaatctcttt
     5581 tgtgatgaca gttgctacaa cattttccat cacgacaccg gcagccggca gagccgtagg
     5641 atcagaacgc tcaacagtag ccttgtaagg ctcgtgcgtc tcagtatcca cagacattag
     5701 gggcttgtag agggtgggaa tcggcttcat cacccctttg acaacaatag gctgaccagt
     5761 agtcatacct gcctcaaagc cacctagtcg gtttgttcga cgactgtagc cgcttgtctc
     5821 atgccaaatg atgtcgtcca tgacctgcga gcctttttgg tagcccatgt caaagcccat
     5881 accaaattcg acccctttaa aggcgttgat agacaggaca gcctgcgcga ttttggcgtc
     5941 taatttacga tcccactgaa catatgaacc taagcctgct ggtaagccat gaatgagtgt
     6001 ttcaataata ccaccaagcg tatctccttc ttttttgact tgatcaatat gggccttgat
     6061 agtcgcctct tgcttgggat tgacaataga taaatcagaa gactctgcta cttttttgat
     6121 atctgcaaag gacatcgcct caggcacagc tacctcgata ccaccaaaaa ctaggacatg
     6181 attagcagtt tcgatcccaa gctcagtaag gattgcctta gcaattgcac caacggccac
     6241 acgcatcgct gtttctctgg cagaggagcg ctcaagcgca tttcttaaat catcaaaacg
     6301 atatttgatc cccccaacca agtcagcatg accagggcgt ggacgagtga ttttacgctt
     6361 gaacttgatt tgctcttcaa cagcctcaac agccataatg tctagccatt tttgatggtc
     6421 cttgttttga atggttaaag taattggtgc tcctgttgtt ttgccatgac gaacacctga
     6481 agagatatgc acacgatctg attcaatgcg catgcgtgcg ccacgaccat atcccccctg
     6541 ccgacgcttc agttccttgt taataagctc agctgataat gctaagcctg caggaattcc
     6601 ctctataatg gccgtcaaag cttgtccatg tgactcacct gctgttaaat acctcattat
     6661 tcctccattt atcaatcata gacataaaaa gcaaacctgc cctcctctag acaactaaaa
     6721 gacattattc taagctatcc aagagaataa tgtctgttac cgtatcttat caatcctcag
     6781 attccaaaac atgaagaatc cttttcatat cagccaagga aacctgccct ggtgcactgg
     6841 cttgatctaa ggacacaaaa gtccacgagg accctacaac atcacctgcc aagcgtgata
     6901 gtctgcctag ctttcccatt gacatggttg caaattcctg ctctgggtta agtgttttaa
     6961 agcctctggt ataattcatc aaatccaaaa cgtcctgctc gctctgtggc atgacagcaa
     7021 tcttgacaac gcgaggagct agcttagtca tctccgaaaa agcctccatc agattttcag
     7081 gcgtctcatc aaaattgtga taagacaaga caagattcgg aaagtcaagc atttcatgaa
     7141 agacagcctt gtgactaaag tattcaaagt caatatagtc aggattataa atcgcattga
     7201 tctccttgat caaatcaacg tattcctgat cagaaagtgt aatatgccct ccttcttgac
     7261 ttgtacgaag ggtaaaaata atctctctac ctgcaaattt ttcaaaaata gctggcgcta
     7321 cagaaacaat atcctcctta ggaagaaagt ctgctcgcca ctcgattaaa ttaacatctt
     7381 gatatttaga aacgtcgata gattgagcct cttcaacatt tcttggcatg actggtgcta
     7441 caattttcat tctcgtaccc ttatagtaaa tacctttaaa taattacttc tttcatctgc
     7501 tttattgata gtaaaatcac ttggaagctg ctcaagtgtc atctgagcta atggcctgcc
     7561 tcccaatcct ttgataattt gctttttaaa ctggttaaca gtcatattgg cagcatttgt
     7621 tgaagcgata attgttccct tgggggccaa taggtctaga gcctcagcga ttaattgatg
     7681 gtaatcctta ctcactgaaa acgtctgctt tttgtttctg gcaaagcttg gtggatcaat
     7741 aataataaga tcaaaagaaa gttgctttcg cttagcatac ttaaaatagt caaaaacgtc
     7801 cataaccaca agctgatgac tggataggtc caactgattt tgaacaaaat gagcctttga
     7861 taactctctg gagcgctttg ccaaatcaac agaggttgtc tcaactgcac cgcccattgc
     7921 tgcagctaca gaaaaagctg ctgtatatga gaacaggttt aaaacagtct ttccaagcgc
     7981 caagccgtcc accagacctc gtctaacctc atgctgatca agaaaaatcc ctgtcatcaa
     8041 gccatcattt aaaaatacct gataggctac gccattttct aaaatggtaa aggtatcagg
     8101 agcaaacgcg ccatacaaat gagccgtctc cttatctggt cccttaaagc gaatcttttc
     8161 ataagctccc ctgacctcag gaaaaacctc tcgaaaagcc tgaataataa gctccttttc
     8221 ttgataaaca aagacattat accaagaaaa taaagcaaag tccttataga ggtctatggt
     8281 tagtcctcca aaatcatcac cgtcttggtt aaaaagacgg taagcatttg tccattcaga
     8341 cgcggcaaaa tgctctcttt tcttcttagc tgtcttaaat aaggtcacaa aataagaaac
     8401 cgacaatttc ttaacagacc ttcctagata ccagcctact cccttatgtt gctttgaaag
     8461 gtaagctgtg ccgatgagct gatgagatga attcacaagc tgcactaact ggtagtccca
     8521 aatggtgcca tcaaaatcct tttcatctag taattgtatc cctgctgcta tcttgcgttc
     8581 aacaagggga ttaatacaga ccttattcat agtttctatt ataacaaaaa ctattaaaaa
     8641 atcatactag atttaaactt attgcaagca ttagctccat atttttggta taatttaatc
     8701 tgagatttta tttggagatt atatctttta ggaaaaaatg
//
LOCUS       DARYLJ010000067         7911 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYLJ010000067 DARYLJ010000000
VERSION     DARYLJ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7911
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..225
                     /locus_tag="TU746_001791"
     CDS             <1..225
                     /locus_tag="TU746_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0892100.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
     gene            694..1296
                     /locus_tag="TU746_001792"
     CDS             694..1296
                     /locus_tag="TU746_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892101.1"
                     /translation="MISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNT
                     DDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETL
                     FRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLG
                     KMIAEIPVDYMLNLLSPGYHIARYIDSIDTVPNNNRINLW"
     gene            complement(1712..2092)
                     /locus_tag="TU746_001793"
     CDS             complement(1712..2092)
                     /locus_tag="TU746_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL0892102.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(2126..3118)
                     /locus_tag="TU746_001794"
     CDS             complement(2126..3118)
                     /locus_tag="TU746_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL0892103.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(3134..3679)
                     /gene="srlA"
                     /locus_tag="TU746_001795"
     CDS             complement(3134..3679)
                     /gene="srlA"
                     /locus_tag="TU746_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL0892104.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(3815..4276)
                     /locus_tag="TU746_001796"
     CDS             complement(3815..4276)
                     /locus_tag="TU746_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL0892105.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(4276..6048)
                     /locus_tag="TU746_001797"
     CDS             complement(4276..6048)
                     /locus_tag="TU746_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL0892106.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(6342..7691)
                     /locus_tag="TU746_001798"
     CDS             complement(6342..7691)
                     /locus_tag="TU746_001798"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL0892107.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         2373 a         1783 c         1554 g         2201 t
ORIGIN      
        1 atccaaggcc aaggcgagca tggacataag ggtcaccatg gaaaagatgc taagccatca
       61 gcacctaaag cagattctaa atcaacagca aaagctatgg cgccagcagc tcaaaagggc
      121 acactgccag ctacagggga gacaaatcac ccattcttca cccttgcagc ccttggtgtt
      181 atcgctagcg ccggcatgct aacattaaaa ggcaagaaaa actaaaccag ccattgcacc
      241 tttcccctta ggcaatgagc tagtaacagc ttttctcatc tcttcaggca gcattgccct
      301 aagaagatga cctaagttca aaaagaggct atcaccagcc tctcaaattg aaaaaagtcc
      361 ttagaaaata atttccaagg gcttttcttt gtataaagtc gtacaataaa agaaaaggat
      421 tgtacagtgt tatctatatt tcataaagac aaactagact ataatcgtaa ctgatacgtt
      481 ttttctatgc gctaatttct tcaacctctt taacaagata gttatgatac tatttctaga
      541 tcatcaaata tcattttcta atgttaatat ctttattata tcataaaaat gttttcaaaa
      601 acagtcttgt tttttaattt attaatgtta aacttaaatt tttgaaagac tagtctaaac
      661 atttattttt aaagaagggc atggtgaatc aatatgattt ctgtaaagaa aaatttatgt
      721 cgcttaggtg ttttgtctag tagtttatta cttttaacag ctgcaacgac tccatctgtc
      781 attgcttttg cggatattca aacaagtgcc ataaaaaata atacagatga cgcagatggt
      841 atgtattttg ttcaaagtta tgaaatgtct gtagaagata aagaattgct tgttcgaaat
      901 gttaaagcaa atcatcctac agtttctgaa gattttatca gagaagttat tgaaagacaa
      961 ttagtaggtg attatacatt acctgaagaa gagactcttt tccgctcagc atggcaaggg
     1021 gttacagtag atcaattggg agcagctcta gatgtggcta ttggtatggc attaacaggt
     1081 ggagctggat caattgctgc tggtgttttg agagtcggaa aaagagaagc tgttggtcgg
     1141 gtaaaatcaa ttctaattaa atatgggcta ggtaaaatga tagctgaaat tccagtcgat
     1201 tacatgttaa atttattatc gccaggatat catatagcta gatatattga tagtattgat
     1261 acagttccta ataataatag aattaacctt tggtaagtta ggaaatttag tactgtgaaa
     1321 aaaatttata ttttatattt tgtgctttat tgcttattat accttgtcat atcattatta
     1381 attagctatg gtatgtccca ttttcttaac atggaattta aatggtggaa taaattagct
     1441 atatctctaa catctttata tattatttat caaatgctga aaaaggataa attaattaaa
     1501 taatcaacta atgtacaagt tgtctttaag ctgaaaagag gctatcaaca gcctcttttt
     1561 ttgatgatat agataagccc aatgcttcct tagaagagct cttctgtgag atgaccttat
     1621 cacctgacat tagctgcttg gctcatgcct acagctaaag gaaatgccct gcaaggatag
     1681 cagcacttag cctgctggtc tacggcgtgt ctcagctgca cctaagccaa gcaaagattt
     1741 gtactaggct gccctgcctg acctgtggca gccctttgcc cttgacatgc agagtaccgg
     1801 gaagagagct ggctgtggag ccatcaaaag aaatggttat atgccctagc tgagcaagat
     1861 ttttttcaac aacagcacct actgctgtga tgtcatatgc catttgatca atgactagct
     1921 gaccaccagc agagatagac ccagacactt gcttgttgtc aatcgtatag caaaagtctg
     1981 ccaagtctgc cggtgctccc tgatcaaaaa gaataagcat attggcagca ctaatcatgt
     2041 ctgccgcctc cgatccaata gcggtaactc ttgtttcaaa tacttttatc atacattctc
     2101 tctcttccta tcatacgata gctccttact gatacaaacc aatacttgca atccaagcaa
     2161 caacaacccg aggaacacca tttaaaaagc gtgaataaag cacagatggc accccaacct
     2221 ctactgtctc agcattagcc tctgataaac caagcgctac tggaatgaaa tcacagccat
     2281 tttgcgtatt aatagcaaaa agtgcaggaa gagccatttg tggtggaata gtgccttttc
     2341 caatctcaac accaatgagc gttccgatga tttgactaat aaccgcacca ggtcctaaca
     2401 gcggtgataa aaatggcaac gaacagataa agccaatgat aatcaagccc caaatattac
     2461 cagccagcgg taccatgagc ttggctagcc aattaccaac accagagcct tggataaaac
     2521 caattaaaag agagacaaat gccatgaatg gcaaaatcgt attgattaag gtctggatag
     2581 cctcacgcgc cgcttggttg aagatagcaa ctaccttacc tgctcccata ccaatgcggg
     2641 caacaaagct gctttctgcg cgctgctcag taatcttttt gctagtatca tagctgctag
     2701 cctttggaac tgatgactcc ttagcactag caacatgagc ctgagcgtca ctggctgtga
     2761 tttgctcaag acctacagca gacacgtaaa tgtcctcggt aatgtactgt gccaagggac
     2821 cgcttttacc tgtcgccacg atattaatgg ttggaatgcc ttttttaggg taaataccgc
     2881 agcgtagggt gccgccacaa tccacaatag ctagggctat ctcatcatca gggattgagg
     2941 tcacaaagcc attgaccgcc tccatacctg ttagggcagc aattttatcg acaatgtcag
     3001 gcttttttcc accgccagta atatagataa atttgtgctt agcttctgtt ggtgtaatgg
     3061 ttagcggccc accatagcca ccgctcccct taacaactgt aatactgtga taagtcatca
     3121 tgctacctct cttctataat tcaatcatct tacttaatgt cacaccctgc tgcttggcca
     3181 cgtaggctgt cgtaaagtca gttacccagc caccaacaaa gttcatgatt aacccaacca
     3241 agaggtaacg aatcgccaag tccatttggc tcaagcctag cgtcttgata cctgaggcaa
     3301 tacctaacca gacaaacaat tctcccggat taatgtgtgg aaagacaccg tttgacgtat
     3361 gacaaaattg catttgagcg gcaacatagc ttggcttgta atactcgggc ataaagcgtc
     3421 ccatgctgat tgccatcgga ttacccagca taaaagctga aataaaaggc aataccatgt
     3481 agcgactgat agggttttta gcagagattt ttgccaattg attgaccctt tgatctccta
     3541 aaataccaat taaggcattc attgcaacca gcagcatcaa gaccaccggc acaatgccag
     3601 tcatccagct gacaaaggtt tcaccaccaa gctggaagag cttcataaag ccttccgcaa
     3661 atcttgttat catttccata aataaactcc tcatatgatg tacttacaag caagacaata
     3721 caaatgtact gcctgcttga taatagctgc ttgagctgga ctcaaaacag cttttatgtt
     3781 gacaaggcaa gcaatcaatc ctgcttttgg caccttactt gaagcgtgcc agcagctgct
     3841 tggcctgtag ggtccaatca aaggctgagg catattttgg tgcgtcctca tagacccctg
     3901 cctcaaccct caagaagacc tctcttgcgt cctcaatagc caagcgcagc aatttatttt
     3961 ctcgtctaat caagggattg tagcgatcaa aataatgaat atcctgaccg atataagctg
     4021 gcattggctt aaacctggct gccactgtca caccctgcat ttgcctagca tctaatacct
     4081 tacctgactg atccaaggca aacatgacaa tggttccggc cctgattttc ccggctctac
     4141 ggccaatagc aacgcgcccc tgtcgtctaa gactggcata aacagcattg aagtgcttaa
     4201 gctgtctcag acctagcaat aattgaaaaa ggtaagcaac tatgacaaat agtccaaaaa
     4261 taaccataaa actcattaaa aaactccttt ttccttggta aatgcaataa actcagcttg
     4321 actttttagg ctccttagct ccgcctgaag cttatcatcg cttgctattt tgaaaatatc
     4381 atcataaatt ttcaagagat cagcctccat ctgcgcttca accctcttgg aaatagccac
     4441 tagaaaaata aactccacca gacagtcatg ctcacgataa ggctcgtcta atagacccag
     4501 cagcaggaca gtctttgttt ccttgtcatt aatcgtatgt ggaaaggcaa tgcgattgcc
     4561 aaataaggtt gattgcaggg cctcacgctc tagcaggcgt tgaccaaact gcctgtcaac
     4621 cagctgcttt tcctcaagca gctccgccat ttcagtcagg tagtcagtgt aggccttccc
     4681 ctttgacaga cgagcaaagt gtagggtgat ggtcgccagg tttttctggt gataatgatg
     4741 taccctgcgc cattcatttt gcagccactg gtcatcaaac agatttgtga tttggagaac
     4801 aggagatttt agctgaccaa acttcagcgg cacagtggtg aatatggcaa aatagtgatc
     4861 attgtcatca ggattgaatt gctcctcaga gaattgtgag atcaacaaat caggacctag
     4921 caccttgctc aagcgacgac aaatcatatt ggcagtgcca cgacctgtcg tgcagacaac
     4981 ggcaattttt ttcactgttg gctctgtcac atgctcagcg tctttcatca tcatttcgaa
     5041 ataaagggcc aaatagctac actcagacaa ttctatggcg cagtcaaact cctctgctaa
     5101 gacctgagct gcgacaatgg ccatatcaaa ggccaagggg tatttgtatc taatttctcc
     5161 atgaaaaata tcattggcct gaacatgaaa aatcaaacga ttcaccaaga gcttcaaatg
     5221 cgtatgcaaa gcaacaaaaa gcttgtcttg gtcaatagtc accaagagac tggtcttgat
     5281 gtgctcaatc atttttgaat aaagcctgac aatgctctgt tgcagaggct tttcttgata
     5341 ggctagatcc tcgatgtatt ggatattcaa gggaaagcta ataaactggc gctcgtattg
     5401 actcagtgac agctgatagg ctagctcaat gtgatagacc agctcctcca taaaggcact
     5461 ggaatcaacc tcattgctat agtaaggaat aggatctgtc agatacctgc cctgacgcat
     5521 tcgctcaatg gttatcgcaa agctcttggt caaaagctct tggattttgc gaggaagctg
     5581 gtaggtctga tacagctcat ctagaaaaaa caagctatca ccacacaagc cctgcggctc
     5641 aaagtatttg taaacctcat gaacataaag cagccgaagg ttcaactcag tgccaacagc
     5701 ctgtatgcca tgattgggct tgccctgaat catgaccgaa taggtcctag caagagcctt
     5761 ggctgccttt aggtctttat tgatcgtgct gcgactgacg ccaatctcat cagccaaatc
     5821 atcaatgact aaagctgagg agctttgcag tagccttttt agaagataag ctacccgctt
     5881 gctagcggaa ttaaagtcac tagccttacg taaactacca gctaatatcg tctctaatct
     5941 agcataatca tagacctgca gctgcaaaaa ggcgccttgt tgggtgatgg tcgcatctcc
     6001 atctaaaatg tcattgagct gaccaatgct acttgcagcg tttgacatcg tcttttcaca
     6061 aagtcacagc ttagaaagct agcagaggag acaaaagcaa gaccttatca gctaacagca
     6121 gcatattaaa cgaacagcta gtgatactga tcctactaag catagagctc caaaagcctg
     6181 gcttaaatag tattcaaaat agaacaagag ctctcaagaa caataaccta gcgcactact
     6241 tgccttgata agcctaaccg accttgaaaa gaagcaaaaa aaagagcctc tcacgagact
     6301 ctttgttatg ttttagcaga ctagtctagc tagctctgtc attacaagcg tgcgttgagc
     6361 gctgctccta gctcttcaaa gcctggctta ccaagaaggg caaacatgtt tttcttgtaa
     6421 gcctcaacac ctggctgatc aaatggattt accccattga ggtagcctga aagggcaata
     6481 gcaagctcaa agaagtagat cgtatagcct agtgtaaatt cgtcttgctc tggaagcgtg
     6541 ataaacatat ttggcacacc accgtctgta tgggcaagaa ggacaccatc tgttgctttt
     6601 ttgttgacaa agtcaacgtc tttgccttgt aggtagccaa ggccatcaag atcctcagcc
     6661 atttctggga taatcacatt ttgacgtggc ttatccacac gaatcactgt ctcaaagagg
     6721 ttacggtagc cttcttggat aaattgacca agagaatgca ggtctgtcga gaaattagct
     6781 gaagttgggt aaataccctt ttggtccttt ccttcagact caccagccag ttgcttccac
     6841 cattcgctaa aatactgcaa tgatggctca tagtttgcca aaatttcagt tacatagcct
     6901 ttgcgataga ggatattgcg aactacagca tattggtaag cgatgttttc tgagatttta
     6961 tctgatgaca ggtccttacg agctgcattt gccccctcca tcagcgcggt aatatcagca
     7021 cccgatgctg caattggcaa caagcccaca gctgtcagca ctgaaaaacg accaccaaca
     7081 ttatctggca caacaaaggt ttcccaatga tttgcatcag cctcaacctt aacagcaccc
     7141 ttgaccttat cagtcgttgc atagatacgc ttgttggcct cttcttgacc gtacttttta
     7201 acaagtaatt ctttaaagac acgaaaggcg attgcaggct ctgttgttgt accagactta
     7261 gaaatcacgt taacagagaa atctttatct tgaacatagt ccacaagatc agcaagatag
     7321 cttgatgaga tggagttccc agcataaaga atttgtggtg ctttgcgctc ttttgctgtt
     7381 tgtaggttgg caaaatggct gttcaaaaag tcaatcgcag ccttagcacc aaggtaagag
     7441 ccaccaatac caatcacaac aagaacgtca ctgtcagcct taatcttctc agctgcttta
     7501 aggatacgag caaattcttc tttgtcatag ttttcaggta actcaagcca gcccaagaaa
     7561 tctgatccag gtccagtgcc ctgacgtagt gcctgatcag cctctgttac ctgaccttgt
     7621 aaaaagtcaa tttcatgctg tccggcaaat tgctcaagaa cctttgaata atcaaatgta
     7681 atatgtgaca ttattttact cccttaactt ttaaagtttc attagtatca taaccttttc
     7741 tattcaatat ttcaatgttt tttatttttg gggagggtgg cctgacttta acgacatgag
     7801 gatcatttct gtctaaaagc agctttgtga tgagcctagc gcttccctat ctgcttctac
     7861 tatagcttac tggggctgat ccgggtgatg tggtagcctc ttggcatagc c
//
LOCUS       DARYLJ010000068         7717 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYLJ010000068 DARYLJ010000000
VERSION     DARYLJ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7717
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..405
                     /locus_tag="TU746_001799"
     CDS             <1..405
                     /locus_tag="TU746_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0892108.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            414..1085
                     /locus_tag="TU746_001800"
     CDS             414..1085
                     /locus_tag="TU746_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892109.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1102..3375
                     /locus_tag="TU746_001801"
     CDS             1102..3375
                     /locus_tag="TU746_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0892110.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3850..5871
                     /locus_tag="TU746_001802"
     CDS             3850..5871
                     /locus_tag="TU746_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0892111.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAEAKARTAEEEAKQATADKEKAETEAKKAKE
                     EAKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDLETQKEKLEQEIKEATEAK
                     NKAEQKLKDLQDSASQGSELSKQLLKEKEELTTKLQELQKQAEEKTTEIEKLKQELEA
                     NKQNSGQLGQQEQKLQEQLNKVQKELKQKEMELKQAQEQLKQEQKPHEGGGDSDASKA
                     RITELEKQVQTLTKEKADLSSTLESTKAQLSETQARLSEAQKQLTAAQEKLTTLEAEK
                     TALQHQVETISKQLSETRDLSEKEKAALQEQINKLKAEIEQKTKEIEALKQGMQSHQG
                     QEKPKDPKTPETPKDPKTPEKNDQPQAPEKRSVPWTALTPAKPIDTTKAPKSSAPSPQ
                     TGAATPKKQLPATGDTATPSFFTAAAMAVLASVGVLNLSPRRKKNQNNR"
     gene            6288..7130
                     /locus_tag="TU746_001803"
     CDS             6288..7130
                     /locus_tag="TU746_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL0892112.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(7233..>7717)
                     /locus_tag="TU746_001804"
     CDS             complement(7233..>7717)
                     /locus_tag="TU746_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL0892113.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         2553 a         1595 c         1541 g         2028 t
ORIGIN      
        1 ggaagaggct tttataaaaa atacatgaat gcctatgggc aggtggcaag gctgcattct
       61 cagcaatggt acaccgatgt cgttcatctt cctgttgaat ttcctatgtc agccgatggg
      121 cataggccag tctctgagag gtaccggaca ctatcagaca aagaaatcag agaaggcttt
      181 ctctccattg gaaaaacacc ggagcttgtc agtggcagtc aggtcgagag attgcgaaaa
      241 atcattaacc tatatgacct gccggttgtc gttccaattg acgaggcagt cactcaagca
      301 gaggagcaaa tcagaaccaa cagagaagct gtctccaagc ggattattga gcagtataaa
      361 gagccttcat taaaagaaaa aataaaattt atatcagaat tttaggagtg tagatgattt
      421 catttaagaa tattagcaag acataccaag tcggagacca agaggttaaa gtattagacg
      481 atgtttcctt tacgattgaa aagggaaggt ttactgttat tttaggcccc tctggttcag
      541 gaaagagcac gctcttaaat ttacttggag gaatggaccg ggcaagcaag ggaaccttta
      601 tctttgaggg taaggacatt acagccttaa atgataaagc attatctgat tatcgcaaag
      661 aggttgtagg ctttgtcttt cagttttaca atcttattcc aagcctaaca gccttagaaa
      721 atatcagtat cgccgcacag ctaaccggaa acacagcaca atcagaggta ttgttggata
      781 aggtggggtt atctcatcgg aaaaacaatt tccctagcca gctgtcaggc ggagaaatgc
      841 agcgcgtatc catagccaga gctctggcaa agaagccaaa attattgcta tgtgatgagc
      901 ctaccggtgc ccttgattcc aaaacagggc agcacattat gcagctactt caggaagcgt
      961 caaaggacga ggacgtagcg gttgtcttgg tgacacataa cactgaattt aaagcttttg
     1021 gcgataccat tatttaccta aaggacggaa agataagctc gattgatcat aaacaatcag
     1081 tttagaggat tggagctaaa catgaaatat cttaatttaa agctaaggcg agatttaaag
     1141 catcattggc agcaattctt ttcagtgttc ttgatgtcct tattaagtgt tttaatcttt
     1201 gttggtctac agggtgcttg gcatgggctg gaaaaaagct tagacaacta tatatctacc
     1261 tctcatttgc caaccgtttg ggtacaggct actaatctaa caaaacagga cattgaaaaa
     1321 atagaggcct taaatcaagt cagcaaggtt agacctaaga ttagggtcac tgctgctatt
     1381 gattctgaca gcgacctaga gcattactta acgctagatt cattacagtc tacctcagat
     1441 caggtgacac gtgttgtagc tggcgaggcc ttttcaacca aagaaaccga taaagtatgg
     1501 ttgaacaagg aatatgctga cgctaaccac ctatccctcg gtgataagat cagcttaaca
     1561 ctatcaggtc aatcaattag tgtgactctt gcgggtcttg tccagtcagc agacaggatc
     1621 tactttacag gcagcttaga gtatatagct cctaattatg ataactatgc ctacggctac
     1681 atctcaaaaa agagcttagc taagctcctt cagacgcagc tgcctgataa tatggttgac
     1741 atttacgcct cgtctgacga tcttcgagac gacatagaga acattttagg caataagctt
     1801 gtttcttatt acaatcaaac aaccctaact gacgtctctg aggcagttga tagagtagga
     1861 cagattagga atctctctta tttgttctcc tttatcttca tcttactagc tattctatcc
     1921 atgtttacca cgatcagacg tctcatcgaa agtcaaacaa aggaaattgc tatcatcaag
     1981 gccttaggct attctaacat acaggtcagt ggccactaca tttcctttgg cttgttggtt
     2041 ggaacattag gtgctctttc tggtcttctg gtatctcctg ctatgtcctg gtttgtccta
     2101 gagacccaaa agagaatgtt ctcacttcct aagtgggaaa ttgcttactc tctgtcttcc
     2161 ctagtagttg cattactggt ggttatgatt tgtgtgacat ctgcttactt tgcttctcga
     2221 aaagccatta aagggctgcc agcagtattc ttacgaggaa aaaacaggga cgtcaagcat
     2281 attttgctcg aaaaaatcaa gcccttatgg cgtagtattt ctgacgaagc taagtgggct
     2341 atacgtgatg ctttgacaca ccgcatcaga attttaatgg ggattatagg ggtagctggt
     2401 agtatgatgc ttttaattgc cggtattggc atgcctatct ctatgaatca ccttgttgat
     2461 aaggcctata acaaggactt tagctactcc aaacgcttga cggtttctga ctacgaatcg
     2521 gccaataagg cctataaagg ccaatgggtg caaatcaatc aagcccactt ctcaaaagat
     2581 gacggctaca atcgtctctt gattattatc agcaagggaa gccttgttaa cgccaccaca
     2641 gaagatggtg acaagataaa agagggtggt ctctatgtta ccaacagctt tgccaagcta
     2701 gccaatatca aggttggaga caagctatct gtcacaccct accaggataa gcatcagtat
     2761 acctttagtg ttaagggaat tctgaccagc gaaactaatc aaggtgccta tatcatggct
     2821 gataccttca aaaaagcagg cggagctttt cacccacaca cattgttagt agataagcaa
     2881 gtttctgctt ctacaatcgc tcaggatcag aatgttttaa ccgtcattga taagtccagc
     2941 caagaaagca atgcctatga ccttgtcaat agtctaatga gtgtcttttt gatgatcatt
     3001 ggctttgcct tgctgctagt catcgttgtg ctgtataatt taggctcttt aaattttgta
     3061 gagcgcacaa gagactacgc aacccttcag gttctaggat tttcaaaaag aaatctccaa
     3121 aacataacaa tgctcgaaaa tctcatgaca acctctgtgg gctggctctt gggaattcct
     3181 atggggattt ggtttttaga gcagtatgtc gccaccttct ctacgatacg tcttgaatat
     3241 acggcttatg tcacttggca ggttctgcta gcggcaagtg tccttgtctg gctaacatca
     3301 ttaatgacca ctcttttcat cagtagaaag attagaacaa ttgacatggt tgatgcctta
     3361 aagggagtcg actaacctca ctttatcaca tacctgactc tctctctttt atggttaagc
     3421 atcatcactg cactggttct gatatgatga ctgataaagc tgtaattgtg ctgtaacaag
     3481 cactgtcatt acatagcaac acccttaaaa acaagcatca gatttggtgc ttgtttttga
     3541 atttattgct aatgctaaac gcaacgatta tcacaaatca tgcagtacac gcttataaca
     3601 gcttaagcat gcccattatt caaaaaacgt tgatcaaaat gacttccctg aagtttagat
     3661 cattcctcaa tttattgata caaatgtgat aaagtcatac gatcttcttg tttattaaaa
     3721 aaaaaaaaaa acgaaactac ggagagaaag atgagctttg tcgtttctca cttccaaccg
     3781 ccatgttaaa atcttctctg agaaagaatg ttataaaaaa taatcattct atcaccaaag
     3841 gagagaaaaa tgataactaa aaaacagaga aaactaaaaa gacacacaac aatcagacgc
     3901 ctgtgtcatc aagccctagc agctaccctc atcacaggaa gcctgatggg aacaggacta
     3961 cttggaaata aagtcgtgta tggggatatg aaaagcgatg ccaaaaaggt attagcaaca
     4021 ttgcaaaaag gtaatcataa acaagagtta aaaaaagttc ttagaactat tggtgatgat
     4081 agtttgctat tattatggtt acttgtatcg ggtgattcca atttagatga aagtaataaa
     4141 agttttgatt atttatcaat ttggaatact ggatctagag ttggtaaagt gatatctcct
     4201 actgaatact ttaaacaaga atcaaaaaac actgaaaata ggcaagctgt ttatagtgaa
     4261 tttaaacaac gcgtagaaga acgatctaaa aaagccaagg aagccactga agcactaaac
     4321 caaaaagctc aattggaggc tacagttaaa aatataaacg aagaacttga aaaaactaga
     4381 gaaggtttta aagttgtgag tgaaaactca aacaaattag aaaaacaatt aatggctgag
     4441 aaaataaaaa cacgtacagc tgaagaaact gccaaacaag ctaaaaccga taaagaaaaa
     4501 gcagaggctg aagctaaaaa agcgaaagag gaagctaaga ctgcggaagg aaaagttaaa
     4561 caagcagaaa ctgagaaaag gaatgcggaa gctaaggcta gaaccgctga agaagaagct
     4621 aaacaagcta cggctgataa agaaaaggca gagactgaag ctaaaaaagc gaaagaagaa
     4681 gctaagaccg ctaaagaagc tgctcatcaa gaacaagaaa aagctaaaca attagaacaa
     4741 gctaatcaac aggctaacca aagagctaat ctggcagaaa aatctaaaaa agatttagaa
     4801 actcaaaaag aaaaacttga acaagagatt aaagaagcta cagaagctaa aaacaaagcc
     4861 gagcaaaaat taaaagacct acaagattca gctagtcaag gcagtgaatt gtctaaacag
     4921 ctgttaaaag aaaaagaaga attaacaaca aaacttcaag agcttcaaaa acaagctgag
     4981 gaaaaaacaa ctgaaattga aaagctaaaa caagagcttg aagctaataa acaaaacagt
     5041 ggtcagctag gtcaacagga acaaaagctt caagagcaat tgaataaggt tcaaaaagag
     5101 ctgaaacaaa aggaaatgga gttaaaacaa gctcaagaac agctgaaaca agaacaaaaa
     5161 cctcacgaag gtggcggaga ttctgacgct tccaaagcaa gaatcactga gctagaaaaa
     5221 caagttcaaa cactaaccaa ggaaaaggca gatctgtcat caacccttga gtcaacaaaa
     5281 gctcaattgt cagagactca agcaagacta tcagaagctc aaaaacaatt gactgctgct
     5341 caagaaaagt taacaacact tgaagccgag aaaacagcgc ttcaacatca agttgagacc
     5401 atttcaaaac agctatcaga aacacgtgac cttagcgaaa aggaaaaagc agcactccaa
     5461 gagcaaatca ataagctaaa ggctgagatt gagcaaaaga ccaaggaaat tgaagcctta
     5521 aagcaaggca tgcaatcaca tcaaggtcaa gaaaaaccaa aggatccaaa aactccggaa
     5581 acaccaaagg atccaaagac tcctgagaaa aacgatcagc cacaagcgcc tgaaaaacgt
     5641 agtgtccctt ggactgctct tacaccagct aagccaattg acactaccaa agctcctaag
     5701 agctcagcac caagcccaca gactggggca gcaacaccta aaaaacaatt accagcaact
     5761 ggtgatacag cgacacctag cttctttacc gctgctgcta tggcagtatt ggctagcgtc
     5821 ggtgtcctaa atctctcacc tagacgcaaa aagaatcaaa acaaccgtta atgtagagac
     5881 tctcatatct ggattgaata acagcaaacc cgacatgagc aaaaacaaat gtctaaccaa
     5941 aaatcactga cattagtact ttaaccaaag cctttgagtc aagctaaaca ggctgtcctg
     6001 cctattggct tgactcgttt tgtgattgtg aaacacacca aggtcaaacc taccttgtcc
     6061 tccattttaa acctactctt ttctcccata cccactttag cttacgcaag aaggtgccta
     6121 atcatcactt ttggtagctt cgatgctcta tataaatgga tcaacaaaga taaatcatac
     6181 aaaactgcga gttgttccta tagtcacgat agctcttaca gatatgaaaa gtaaatacag
     6241 ctattaaaaa tatggtacaa taggggtacg atttttagga ggcatgtatg gtttcagttc
     6301 tttcacgagt gattaaggga ataattattg cgcttggctt tattttaccg ggagtatctg
     6361 gaggagtatt agccgctatc cttgggatct atgagcgtat cattgccttt ttagctcata
     6421 tacgtgagca ttttgttgag aatgttctct ttttcctgcc tgttggggtt ggtggtattt
     6481 tagggattgc cctcttttct taccctgttg actatctgct caagcactat caggtaccag
     6541 tcttatgggg cttcgctggg gccatcatag gaaccgtacc tagcctgata aagacttcga
     6601 caaaaacatc tcagcgtgac caagttgatt ggctctggct agtattaacc tttgtcctat
     6661 caggactggg actttatttc ttaaatgatc tcgttgggac aatacctgca agctttaccg
     6721 cctttgtcct agctggtgcc ttgattgctt taggtatttt ggtacctggt cttagcccgt
     6781 ctaatctttt attaatttta ggactttact cacccatgct gattggcttt aaatcacttg
     6841 atttggtagg aaccttttta cccattgcta ttggtggctt attaaccatg ctagcttttt
     6901 ccaagattat ggattttgct ctcaagcact accattcacg cgtttaccac tttattatcg
     6961 gtatcgtcct atccagcacc ctgcttattt taattccaaa tagcagtaat aaggaagcta
     7021 tctcttacgc cggtgcaggt cttggcacct ggctaatggc tctgctatta tttggccttg
     7081 gtgtctggct tggtctatgg atgagccagc ttgaggagaa atacaaataa cactcgatac
     7141 accagcaagt acctctaaca gcagcattaa gatcaaaaaa acgaatgact agctctcagc
     7201 cttatcacca gctgtgacta gcattcgttt ttttatatgt catcatgctg tcttgcctct
     7261 gtcacgattt ctataaaacg gttcgtcaat tgagcagtta taccccagat aggcttttct
     7321 aaatgctcat agagtaatac ctgatcttgc atgtacctca acctgtactg ctctccatta
     7381 gggatacgat ccaacggaaa gtctgacgag attatcgatt gcatttgtaa aggataagca
     7441 acaggagctt gcgccatgag ctcctccaaa ggcaccgtaa acaagctatc aacctcttca
     7501 ttgaccctaa gccttctcca atcatcaata gccagttccg caacaaagca atgaatgcta
     7561 cgagtcggct gaactaaata gtcaatctcc ccccaaacat gaacctgctc aggctctata
     7621 ttgagctcct ctaccgtctc acgaatagcc gcctgctgat aagtctcacc ctcctccacg
     7681 cgcccactag gaaaagaaac ctcccctggc ttgaatg
//
LOCUS       DARYLJ010000069         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYLJ010000069 DARYLJ010000000
VERSION     DARYLJ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            436..975
                     /locus_tag="TU746_001805"
     CDS             436..975
                     /locus_tag="TU746_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892114.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TU746_001806"
     CDS             972..2087
                     /locus_tag="TU746_001806"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL0892115.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGRYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TU746_001807"
     CDS             2077..3339
                     /locus_tag="TU746_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL0892116.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TU746_001808"
     CDS             3385..4404
                     /locus_tag="TU746_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL0892117.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TU746_001809"
     CDS             4603..5313
                     /locus_tag="TU746_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0892118.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TU746_001810"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TU746_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL0892119.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TU746_001811"
     CDS             6662..7471
                     /locus_tag="TU746_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0892120.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2018 a         1599 c         1799 g         2079 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaagg tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt actggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYLJ010000070         7325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYLJ010000070 DARYLJ010000000
VERSION     DARYLJ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..351
                     /locus_tag="TU746_001812"
     CDS             <1..351
                     /locus_tag="TU746_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0892121.1"
                     /translation="RGEQGPKGDRGEQGPKGDRGEQGPKGERGEQGPKGDRGEQGPKK
                     EPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLPSTGDTSQSFVAAALGF
                     IASAGLLVFKRKKN"
     gene            877..1767
                     /gene="rapZ"
                     /locus_tag="TU746_001813"
     CDS             877..1767
                     /gene="rapZ"
                     /locus_tag="TU746_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL0892122.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            1764..2741
                     /locus_tag="TU746_001814"
     CDS             1764..2741
                     /locus_tag="TU746_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL0892123.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            2738..3649
                     /gene="whiA"
                     /locus_tag="TU746_001815"
     CDS             2738..3649
                     /gene="whiA"
                     /locus_tag="TU746_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL0892124.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            4009..5406
                     /locus_tag="TU746_001816"
     CDS             4009..5406
                     /locus_tag="TU746_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL0892125.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            5646..7196
                     /locus_tag="TU746_001817"
     CDS             5646..7196
                     /locus_tag="TU746_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL0892126.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
BASE COUNT         2160 a         1488 c         1681 g         1996 t
ORIGIN      
        1 cgtggcgagc aaggaccaaa aggtgatcgt ggcgaacaag gaccaaaggg tgatcgtggc
       61 gagcaaggac caaaaggtga acgcggtgag caaggaccaa aaggcgatcg tggcgagcaa
      121 ggtccaaaga aggagccaga aaaagacacc aagccatcag tgccaaaggc accagataat
      181 atggctgcac caaaggctcc ggagaagaag aaccctaaag caccggctcc taagtcagct
      241 ccaaaggcat cattgccatc aacaggagac actagccaat catttgttgc agcagccctt
      301 ggctttatcg ctagcgcggg cttgctagtc ttcaaaagaa agaaaaacta agctagctaa
      361 agactgtaaa caagcctcaa ctgttacagc aagcctcttt gacatcttgc agataagagg
      421 atttcttagc gaatgaagtg tgtctaaagt cagatactct gctggactag cagtagctga
      481 tctccctgaa aatcagttat gctaaagcat tgagccttag ttgcaaggct taggtgtgac
      541 cttccaaagg aagctgcttt tgcctgtatc actttaggaa gatatctaaa agagacactt
      601 ttttcacgct gaagctaagc tagcttttcc tatgacaaat atcctataac aataaactcc
      661 aaacaaaaga gaggtcaaat ggtacctctc ttttacttag ctttaggatt gatagattct
      721 aaaggcttcc ttgtttcttg atcaagaagt ccttactgat agagtctgtc ttagccgggc
      781 ttatatggta taatacctaa tggagataag aaaagtcctt aacaaataga gtttcatcta
      841 ttgttacagg agcaaccaag tgaaaggaga tgctacatgt cagataaaca aatcaatttg
      901 gttattgtta caggaatgag tggcgccggc aaaacagttg ccattcaatc atttgaggat
      961 ttggggtatt ttactgttga taacatgcca ccagctttag tgcctaaatt tttagagctg
     1021 cttgagagga ccaatgaaac ccaaaaggtt gctctggtag tggatatgcg cagcagacgc
     1081 tttttcaagg agattaactc tatcttagat catattgagc taaatgccaa cctcaagcta
     1141 cggatcctct ttcttgatgc gactgatagt gagctagtgt cacgctataa ggaaactaga
     1201 agaagtcacc ctctggctgc tgatggtcgg gtgcttgatg ggattcgacg agaaagagag
     1261 ctgttagtcc cgcttaagag catgagtcag catgtggtca ataccaccga tctaacccca
     1321 agacagctgc gtaaggtgat ttcggatcag ttttcaagcg agtcagacca agcctcattt
     1381 agaattgagg tgatgagctt tggctttaaa tatggcctcc ccttagatgc ggaccttgtc
     1441 tttgatgtgc gctttttgcc taatccttat tatcaggtgg cgctaagaga gcagacaggg
     1501 cttgatcagg ctgtttttga ttatgtgatg actcatcaag agtcagaggc cttttataat
     1561 catttgttag gcttgattgt tcctattttg cctgcttatc aaaaggaagg caaatcagtg
     1621 ctaaccattg ctattggctg tacaggtggt cagcatagaa gcgtcgcctt tgcccatcgc
     1681 ttggcccaag acttgacagc agactggccg ctgcatgaga gtcatcggga catcaatcgt
     1741 cgtaaggaaa cggtaaatcg ctcatgagaa atcctaaaat aacggtgata ggaggaggaa
     1801 caggtattcc tgttatccta aaaagccttc gcaaggaggc ggttgacatt actgcggtgg
     1861 tcactgttgc tgatgatggt gggtcatctg gtaagctgcg caatgccatg cagcttaccc
     1921 cgccaggtga tttgcgcaac gtcttgttgg ccatgagtga catgcctaag ttttatgagc
     1981 gtgtgtttca gtatcgtttt aatgaggcag atggtgctct agctggtcat cctctaggca
     2041 atttaattat cgcaggtatt tctgagatgc agggatccac ctataacgct attcagattt
     2101 tgacgaaatt tttccatatc accggcaaga tttttccctc aagcgagcag cccttgacac
     2161 tgcatgctgt ctttaaggac ggtcatgagg tgtcaggaga aagctctatt gccagctacc
     2221 aaggcatgat tgaccatgtc tatgtgacca atacctacaa tgatgacctg ccaaaggcca
     2281 gtcgtaaggt ggttgaggcc attctccaaa gtgatatgat tgtgcttggt cctggttcct
     2341 tgtttacctc tattttgccc aatcttgtaa ttccagagat caaagaagcc ctgagagtaa
     2401 ccaaggcaga ggtggtttat atttgtaaca ttatgaccca gtacggtgag acagagcaat
     2461 tttccgatgc ggatcatgtt gcggttttaa atcagcatct gggcagggac ttaattgaca
     2521 ctgttttggt taatgttgag caggtgccaa aaagctatat gaattccaac caatttgacg
     2581 aatatctggt ccaagtagag catgactttg caggtctgtg taagaccgca aagcgtatca
     2641 tctcgtctaa ttttctgcgt ttggagaatg gcggagcctt tcatgacggg cacttggttg
     2701 tagaagaatt aatgaaccta gttaggataa ccaagctatg agttttacga caactgttaa
     2761 agaagaattg attcatttat ctgcttctga tcaaacagaa ttatcagcaa tcatcaagct
     2821 ggctggtagc ctaggcttgg ctaatcagag cttgaatttg tctatcacaa ctgaaaacgc
     2881 taagattgct cgctacatct atgcgcttat cgaagacacc tatcatatca ttccagaaat
     2941 caggtaccat caaaagacca acttgaaaaa aaatcgtgtc tatacggttt atttggataa
     3001 gcaggtggat aagctcttag cagatttaaa gctggcagat tctttttttg gcattgagac
     3061 aggtattgag cagcaggtca tgtcagatga tgatgctggt cgggcctatc tcaagggtgc
     3121 ttttttagcg gcagggactg taagggatcc agaatccggc aagtatcagc tagagatcta
     3181 ctctgtctat ctagaccatg ctcaggattt ggcccagctc atgcacaaat tcatgctaga
     3241 tgccaaggtt atcgagagaa aaaatggtgc agtaacctat ttgcaaaagg ctgaggacat
     3301 catggatttt ctcattatta ttggtgccat gtcgtgtaag gaggagtttg aggctgttaa
     3361 gcttttgcgt gaggcgagaa atgacatcaa tcgggccaat aatgcagaga ctgctaatat
     3421 tgctaaaacc atcaccgcca gcatgagaac cattaataat attatcaaaa tcatggatac
     3481 gattggctta gacagcctgc cagttgagct gcagcagatt gcccagatga gagtagccaa
     3541 cccagactat tctcttcaac aaatcgcaga ttcgcttgac tttgccatca ctaagagtgg
     3601 ggtcaaccat cgcctgcgaa aaatcaataa gctggcagag gatttataaa gacagcttag
     3661 cctttttcag gctgataaaa aagggggtaa ggtgatacga acaagccgcc ttttaaggca
     3721 tgccttgttg agctttctct aggctgttga tggagtgatc tcaaggcgct tttgttactg
     3781 tcattccaac aggctatctg attttgggat gacttcttac taataagctt ttctaatggc
     3841 tggctgacaa cgattagcga tatagttaag gcttatcgtg attcaacaag aggctttagt
     3901 ctcttttttg cttgtcagaa ttattttttt aggcttttct tacaaatgag aggacaatgt
     3961 gacaatctgt ggtatgatat tagtaatgaa tacaaaggag aacaaatcat gtcatgcaca
     4021 actattcttg tcggtaaaaa agcgacctat gatggatcaa caatcgttgc tcgtacagag
     4081 gattcacaaa atggggaatt tacccctaaa aaaatgacag ttgttagacc aaaagaccaa
     4141 cctagacact atcaatctgt cttgtctagc tttagcatgg agctgccgga tcagccgatg
     4201 gcttatacct cggtgcctga tgccctagga aaggacggta tctggggaga agcaggtgtc
     4261 aataccctca atgttgctat gtcagcaact gagaccatta cttcaaatgc tcgcgttctt
     4321 ggagcagatc ctcttgtttc ctctggtatt ggagaagagg acatgctgac cttggtgctt
     4381 ccttatattc ggtctgcaag agagggtgtt cttcgtttgg gagctatcct agaagcatac
     4441 ggtacctatg aggctaacgg tgttgccttt tctgatgagc atgagatttg gtggctggaa
     4501 acaataggtg gtcatcattg gattgcaagg cgcgttcctg atgatgctta tgtcactaat
     4561 cccaaccagt ttggccttga tcactttgaa tttaacaatc cagaggaata cctgtgttcc
     4621 aaggatttaa aggactttat tgccaaatat catctagatt tgacctatag caacgagcat
     4681 tttaaccctc gctacgcctt tggtagccaa agagataagg atcgccatta caatacacca
     4741 cgcgcttgga ttatgcagca atactttaat ccggagtttc tgcaggatcc gcgcagcttt
     4801 gaacttcctt ggtgccaaag acctgatcgc aaggtgacca ttgaagacgt taagtacgtg
     4861 cttagcaatc attatcagga caccccttat gatccttacg gcccagaggg aacgccgact
     4921 agtcgaaaat cctttaggcc gattggtatt aaccgtacga gtcaaactgc tattttacat
     4981 atccgtccca acaagcctaa ggaaattgct gccattcagt ggatggccta tggttcgatg
     5041 ccctttaata caatcgttcc gctattcacc caggtcaaga ccattccaga ttattttgca
     5101 aacactgttg aaaatgtttc cacagacaat ttctattgga ccaatcgctt gattgcagcc
     5161 ctggctgatc ctcacttcaa gcaccatgaa gcagatttgg aggactatct cgaaaaaaca
     5221 atggccaagg gtcatgccat gctgcatgct gttgaagcag cgctagtaaa aggtcagccg
     5281 gttgacctag aagaggccaa ccaaggcatg agtgatgaca ttcaggcaga tacacaggct
     5341 ctgctcaata agatcctctt tgatgctagc aatctcatga ccaaccgctt tagcctaagc
     5401 gactaagtaa tctcaatagt caaacgagct catatcatta tagatatggg ctcttagctt
     5461 gaaaaggata gtagagcggt cttatagtca gactaattaa tggtaacgat gagtccagtt
     5521 aaggtaaaaa aagagcactt agctaatgca aaaaaagtaa aaaacttgca aaagaatgat
     5581 attgtgttat acttaaccag taaatattaa gagctatttg cgatatgata tatagaggag
     5641 gaatcatgaa aaagaagtat cttttaatga tgagtgtgct cggtgtcttt tttgcgggac
     5701 agatcagtca agcaaaacag gtcctagcag atagtaaggt caaaattgtt accaccttct
     5761 atcctgttta tgaatttacc aaaggcgttg tcggaggtga gggaaatgtg tctatgctga
     5821 tgaaagcagg aacagagcct catgattttg agccgtcaac aaaggacatc aaaaagatcc
     5881 aagatgccga tgcctttgtt tatatggacg ataatatgga aacttgggtc cctgatatga
     5941 agaaatcact gacttctaag aaggttacgg tgattaaggg aacaggagat atgctattgg
     6001 tagctggctc tggtcacagc cacgagcatg accatgacga tgccgataaa aagcatgatc
     6061 atgaccacga cgaggaagga cacagccatg cttttgaccc gcacgtatgg ttgtcacctt
     6121 atcgcagcat caccgttgtc gaaacaattc gtgatggtct atctaaggcc tatcctgaca
     6181 aggctgacca cttcaaatct aatgccgctg cttatattga aaagctcaag gaattagata
     6241 aggagtatag tgacgctttt tcagctgcca agcaaaagag ctttgtgact cagcacgcag
     6301 cctttggtta tatggcgctt gattatggct tgaaccaaat ctcaatcaat ggtgtcacac
     6361 cagatacgga gccttcagct aagcgcattg cagagctatc aaaatacgtc aaaaaatatg
     6421 acattaacta catttatttt gaagaaaatg cttcaagcaa ggttgccaaa accctagcca
     6481 aggaggctgg tgtcaaatca gctgtcctta gtccgcttga aggcctaact gaaaaggaca
     6541 tgaaggccgg caaggattac tttaccgtta tgcgtgaaaa cctcaaaacc ctacgcttaa
     6601 caactgatgt agaaggaaaa gaaattcttc cagaagagga taccactaaa actgtttata
     6661 atggctactt taaggataag caggtcaaag accgcaaatt gtctgattgg tctggtaact
     6721 ggcagtctgt ttacccattc cttcaagacg gtacattaga tcaggtatgg gactataagg
     6781 ctaaaaaatc taaaggaaaa atgaccgcag ctgaatacaa ggattattac accactggct
     6841 atcagacaga tgtcagtcat atcaagatta atggtaagaa aaataccatg acctttgttc
     6901 gtaatggtga aaataaaacc tttacttata agtacgtcgg taaaaagatt ttgacctatc
     6961 caaagggcaa tcgtggcgtg cgcttcatgt ttgaagctaa ggagccagac gctggtgaat
     7021 ttaaatatgt tcagttcagt gaccatgcta tcgcaccagg taaggcggag catttccacc
     7081 tatactgggg tggtgacagc caagaaaagc ttcacaaaga gctagagcat tggccaactt
     7141 actatgatgc ggacctatca ggtcgtgccg ttgcccaaga aatcaatgct cattaaccac
     7201 tcaaaagact aggcagttca atcggcctag ttttttcttg tcttagttgc tgtataggac
     7261 ctaaatgctg atagctggtc ttaagattta tttttaattt ttctaactat atttaggttg
     7321 tattt
//
LOCUS       DARYLJ010000071         7012 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYLJ010000071 DARYLJ010000000
VERSION     DARYLJ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7012
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(171..461)
                     /locus_tag="TU746_001818"
     CDS             complement(171..461)
                     /locus_tag="TU746_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892127.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TU746_001819"
     CDS             complement(442..834)
                     /locus_tag="TU746_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892128.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TU746_001820"
     CDS             complement(816..2105)
                     /locus_tag="TU746_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892129.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..2538)
                     /locus_tag="TU746_001821"
     CDS             complement(2107..2538)
                     /locus_tag="TU746_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892130.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLEGVSITYSREKRS"
     gene            2877..2963
                     /locus_tag="TU746_001822"
     CDS             2877..2963
                     /locus_tag="TU746_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0892131.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            complement(3311..5752)
                     /locus_tag="TU746_001823"
     CDS             complement(3311..5752)
                     /locus_tag="TU746_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0892132.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(5752..6213)
                     /locus_tag="TU746_001824"
     CDS             complement(5752..6213)
                     /locus_tag="TU746_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL0892133.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            complement(6383..6586)
                     /locus_tag="TU746_001825"
     CDS             complement(6383..6586)
                     /locus_tag="TU746_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL0892134.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            complement(6799..6869)
                     /locus_tag="TU746_001826"
     tRNA            complement(6799..6869)
                     /locus_tag="TU746_001826"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6835..6837),aa:Cys,seq:gca)
BASE COUNT         1981 a         1650 c         1267 g         2114 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tcctattaga atcattaaag caataaaagc
     2521 tttggtcgac tttttcatga aagttctcct ttcaatttct aataatagta tacaataaat
     2581 cagaagtcat agaataacca tattcaattt ttatgtcgta ttcgataaaa aatataccat
     2641 ctcaacaaac aatcgcttaa aaacgatttt agggtatatt tcttccctgc aagcaaagga
     2701 cacaaaaaag ccatctgaat tttcaacatc agacagctat ttcgtatgac tatggtataa
     2761 tggtttctgc agaaaagtta aggcggtggc tctaatttct gaaaggtggt ggtgcttatg
     2821 actgtaagtg ctaaaatcca aagagaaagg agcgaatatt gtccgtttac gaggcaatgc
     2881 aactcatgct tgggttcggt agttttctac tttcactcat tggcttagtt gttattatcg
     2941 taaaaatgag caataaaaaa taaccgtcta actttagcga gtaacggtta ttttttaact
     3001 aaaaacaagc taccgtctta aacggttctg cattgggtag ttgttttgag caactgtcct
     3061 ttttctattt tcattatatc tcagctaaga aaaatagtca aatgagatac tattttggca
     3121 gctaaattgg tagctaaatc ttcaaaatac ctatttttcg ctaaattcga ttaaaattaa
     3181 atcctatctg tctgctacgc tttaaactct cactctagta cttcatcacc atacgacaaa
     3241 aagagcctga gaaacttttt gtctcagact ctctcaaagc tcttagctta atatcaagca
     3301 aagtcatgca ttaagcgata tcaaaagcta gttttccacg tgatacacca atcttgaggc
     3361 tttgaccgct tgataactct cctgacagca ttaattctgc taacctgtcc tcaacctctg
     3421 tttgcaaggt gcgacgaagt gggcgagcgc ccatttcaac atcgtaacca gcttcagaca
     3481 agtacttgag agctgatggc tggaacttaa ggctaatatg cttttctgcc aaggctgcaa
     3541 tcagcggctt aaccataatt ttcaccacat cacgcatgtt ttcctgtgtt aggctatgga
     3601 agaccacctt ttcatcaatt ctgttgataa attcaggccg ataagccttt ttcaattcct
     3661 ctaaaatacg cttttccatt gcttgatggt catgaccgat cgctttagcg ccaaatccaa
     3721 ccgtcttatc atctcttaga gcagttgctc ctaggttgct cgtcatgata ataatcgtgt
     3781 ttgaaaaatc aaccttacat ccacgactat ctgttaacat accatcatca aggacctgca
     3841 gcaggatatt aaagatgtct gggtgagcct tttcaacctc atcaaaaaga agaacggcat
     3901 aaggcttatt tctaaccttt tcggttagct ctcctccctc atcatagcca acatagccag
     3961 gaggagcccc attaagacgg gaggctgcaa atttttccat gtactcagac atatcaaaac
     4021 gaataagggc tgactcatca tcaaagagta attcggccaa ggcctttgct agctctgttt
     4081 ttccgacacc agttggacca agaaacataa aggagccaat cggacgcctg cctgtgcgaa
     4141 tgcctgactg gttacgacga atggctcgtg caatagcaga aacagccatt tcctgaccaa
     4201 caacacgctt atgcaattcc ttttccagat tcaggtattt tttactatcc gcctgagtta
     4261 gtttttctag gggaatacct gatagcttgc ttaaggtgtg taacatatca tcttcagtaa
     4321 ctgctgttgg ttttagcttt ggttgcttat cctctttgac taaaagggct gacaccttgc
     4381 tcatatcacc atcaagcagg gcttgatcaa gcggtgttat aaagtcaggc tgcgtctttt
     4441 taaccatact ttgcaccatc gcactggctt catcaagcag atcaatcgct gagtctggaa
     4501 gctgcttact tgtcaaatag cgccgagcca gcttcacagc agtatggaca gctgtatcag
     4561 agattgttac attatggtac tgttcatagg aaggcttcaa gccaagcaaa atctgataag
     4621 cgtcctcaac actaggctcc tcaatcaata tcttggcaaa gcgacgagaa agggctgcgt
     4681 ccttttcaat gtgcttttga tattcctctt gagttgtagc gccaaccata tgcagggtac
     4741 cgcgagaaag ggctggcttt agaatattag cggcatcaag tgtgctgtca ataccacttc
     4801 ctgatcccat aatggtatgt agctcatcga caaacaaaat gatcttacca tctgcttcaa
     4861 tatcgtcaat gagttgattc atgcgctctt caaaatcccc acgaaaacgg gtacctgcaa
     4921 ccacactcat catgtcaagc tccaagacac gcatgtcttg taattcataa ggaatggctc
     4981 cattagcaat tcgctgcgct aagccataag ctagagcagt ttttccgaca cccgcatcac
     5041 caacaagaac aggattattt ttcgtcttac gacaaagcac ctgaaccata cgtgacacct
     5101 ctttttctcg tccgatgact ggctctaata agccctgtct tgccatctct gtcaggtctc
     5161 ttgtaaagtc tgatagctca ccagctgtac tctgtggctt catcatttca gaaaaggtgc
     5221 ctactgattt actcttttta ggcttacgca actcatgaat cgccttaata gtttccttgc
     5281 tatagccggc atttagctca atagccttac gtaaatccgc aaacctaggc tctcccttgc
     5341 cagaatcctt gagcctgtag cctgccaatt ctaacagacg actggccata atatccggat
     5401 tgagcaaaat agcaaagagt acatgctctg agccaacctc atgctcattg ataacctgac
     5461 agatagcatg agcaaatgct agtatttctg ataaggcctt ggattgtggc ttgaattgga
     5521 cagaagtcac ctctttggga ctttttccca tggctaaaat agcagcagcc tcatactctt
     5581 cagccctaat ctttcgttca aattcgctta acaccatggc cgctaaggaa tggtcaacag
     5641 ctaccatagc taataaaata tgccaggtct caaggtaagg actatcaaag cgctctgctt
     5701 gaaattgagc ctgattaaaa atgtcttgca tctttaatga ataaatcatc actaattgct
     5761 tccctttcta tcaattcgtt gcaataggcg ataaagcata cgagcacgaa tttctggtgc
     5821 ttgatgtccc aaaacatcat tagaagctac agctaagata atgtttcctt cgcgctctgt
     5881 taacagttgc tcatcaaaaa gcagctgaat cgaatctgta aaggcctgct cgcttaaaca
     5941 atcatcaata gaagcgatca acgtaccaat caggtggtgc ttatccgaaa aatgaacctt
     6001 agcaatacga atgtagccac caccaccacg cttactttct acctcatagc ctctgctttc
     6061 tgtaaaacgg gtcttgatca cataattaat ctggcttggt actacttgaa aggaatccgc
     6121 cagcatggag cgcttgatct ctgcgattcc tgattgggct aacaattctt tgatatattc
     6181 ttcgatacta tcggaagtat tttttgttgg catgccgtca ctcctttgct aaaacgattc
     6241 atttgctgct ttaagccttt atttgactaa aactgactaa cattatatca aatagcagtc
     6301 actaaaagca aatggaaatc actagaatgt aaaaggacag gtgctatcaa caacacccat
     6361 cccctattat ctgctcacta gattaagaca atttagtgat atttactgcc tgaggaccgc
     6421 gctgtccgtc ttcaacatca aacgtcaccc tttgtccctc gtctaacgat ctaaagccgt
     6481 cagactggat tgctgaaaaa tgtgcaaaaa catcttgacc attttcagtt gaaataaagc
     6541 caaagccctt ttcagcatta aaccacttga ctgtaccttg tgccatagtc atccacttcc
     6601 tttctataac gcatttgtaa acatagagag aaataaagat gccaaaacac aactactaat
     6661 tcaaaaacta atttactcgc tcagtgtaac acgaatggca gccactgtca acacataccc
     6721 ctcacaatga cagcttttct actccacctg ctaaaatgta aaaaagcaaa gtcatgctga
     6781 ccttgcttta acaatctaag gcggtagacg gatttgaacc gacgatcaag cttttgcaga
     6841 gccgtgcctt accacttggc tataccgcca taacaagaac tattttaccc tagttgatag
     6901 cattcgtcaa gataaaaata gcagctattt tttagcaggc tgctcctttt ttcggtttat
     6961 gttatttttt agagtttaaa tcagaaaatc atttttaata atattaaaat ta
//
LOCUS       DARYLJ010000072         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYLJ010000072 DARYLJ010000000
VERSION     DARYLJ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(25..486)
                     /locus_tag="TU746_001827"
     CDS             complement(25..486)
                     /locus_tag="TU746_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL0892135.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TU746_001828"
     CDS             complement(530..1606)
                     /locus_tag="TU746_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL0892136.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TU746_001829"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TU746_001829"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL0892137.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TU746_001830"
     CDS             4915..5859
                     /locus_tag="TU746_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL0892138.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            6118..6768
                     /locus_tag="TU746_001831"
     CDS             6118..6768
                     /locus_tag="TU746_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL0892139.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1997 a         1792 c         1335 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attgccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYLJ010000073         6802 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYLJ010000073 DARYLJ010000000
VERSION     DARYLJ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6802
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..692)
                     /locus_tag="TU746_001832"
     CDS             complement(<1..692)
                     /locus_tag="TU746_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEL0892140.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLAT"
     gene            complement(819..2435)
                     /locus_tag="TU746_001833"
     CDS             complement(819..2435)
                     /locus_tag="TU746_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0892141.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(2851..4395)
                     /locus_tag="TU746_001834"
     CDS             complement(2851..4395)
                     /locus_tag="TU746_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL0892142.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDIEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(4564..5259)
                     /locus_tag="TU746_001835"
     CDS             complement(4564..5259)
                     /locus_tag="TU746_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL0892143.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(5343..6728)
                     /locus_tag="TU746_001836"
     CDS             complement(5343..6728)
                     /locus_tag="TU746_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL0892144.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2026 a         1625 c         1262 g         1889 t
ORIGIN      
        1 gtcgctaaaa aaatagagcc taaaatgaaa ataccccgat gattttccgg actaaccaat
       61 aagtgcagcg cataataggg attgatagcc tttaggattt ccaaatgctg taagctattc
      121 aagagaccac tgatccccaa aacgctaaac caaaccagca tgactggccc aaataattta
      181 ccaataacac ccgttccaaa gcgctgcagg ccaaacaaga ccatcaatat cagcaaggtc
      241 gttaggatca cattggtctg attctggtaa atactgctga gctcaggaac agcctttaag
      301 ccttcaatgg ctgatgtgac cgtaacagct ggtgtcaagg caccatctga taagagcgtt
      361 gctcccccaa gcatagctgg aatgattaac caccttgaca tccttctaac taaggtaaag
      421 agtgaaaaaa tccctccctc atgatgatta tcagccttta aagcaatcaa aacatacttg
      481 attgtcgtta ccaaggttag agtccaaata atcaaggata ctgagcctaa aataaaagct
      541 tcagacacct gtgaaaggcc gccttgattg tcaaccaacg actgcatggt atacagtgga
      601 cttgtgccaa tatcaccata gacaattcct agtgcaataa taaaacctgc ctttgttgct
      661 ttatcaaagg catcatgatg ggcattagac atcccaatgt tcctcctaag acttaatcat
      721 gccaaatgga ctgagaccat tatagcaaaa tctataacaa aatcaatatt ttcagaaaat
      781 taaaaagaga gctgacaatc atcagctctc ttgaaacttt agttcccttt atgacggata
      841 ataaatccag acgtcttagc ttcgacagcc ttgcccttct tgtgcaggtc cttgttagag
      901 cgtttttgct ttcgcttaaa gtcatagcta ccactgctat catgactgtc acgtttatca
      961 cgccttggac ggcggtcacc atcataaaca tttcttttct catgacgata gccacctcga
     1021 cggttatcac gaccgctacg actacgattg ccacgacctg tcttgccatt tttattgcca
     1081 tgaccaccac caacatactt aaacggtaat ggcttttcac gcgctatctc aacctctggt
     1141 aaggtatctg gatcttggac ggtcaagcta aggatataga gcgctagctc ctctggggta
     1201 aactctgctg ccaatttcat cgcatcgccc ttaaatttct caaagtttga gcgaatagca
     1261 tcatctgcaa aatcacgctc aatttttttg agggcaacct ttttcttagc ctgaaaggct
     1321 tcctctgccg tagctggctt gagtggcttc atgcgcttct tagtcaggtg ctcaatcatg
     1381 gtcagatagc ccatctcatt tggtgagaca aaggtaatgg attcccctga cttacctgca
     1441 cgaccggtcc ggccaatacg gtgcacatag ctttctggat cctgtgtaat atcgtaattg
     1501 tacacatgag taacgcctga aatatcaagc ccacgcgcag caacatcggt tgccactaaa
     1561 atatcaagtt gatcattttt aaagtcgcgt atgacacgaa ggcgcttatt ttggtcaagg
     1621 tcaccatgta tcccttctgc gcgaaaacca cgcaatttta agccgcgcgt gatttcatca
     1681 acacgacgct ttgtgcgacc aaatacaatt gatagctctg gctgctgaac gtccatcaga
     1741 cgtgtcatgg tatcaaattt ttcttgctcc ttaacacgca catagtattg atcaacattc
     1801 acatttgtta attccttgtt tttaacctga acatgctcag gatccttcat aaacttgaca
     1861 ccaatttcct tgattggagc tggcattgtt gctgaaaata acagggtttg acgatcgtca
     1921 gggacacgac taataatcgc ttcaatgtcc tctaaaaatc ccatattcaa gcattcatca
     1981 gcttcatcta aaatgagtgt ctcaacatgg tctagcctca aggccttacg cttaatcaaa
     2041 tctaacagac gtcctggcgt tccaacaacg acatgcgccc cagactttag ggccttaatt
     2101 tgcttctcaa tgcttgagcc accatatact gagcgaacct tgacgccttt atcacgacca
     2161 aaacggaaca gctcttcctg actttggaca gccagctcac gcgtcggagc aatcaccaat
     2221 gcctgaatgg tgttatcggc tgtacgaatc ttattcagag ttggtagacc aaaggctgct
     2281 gtttttcctg ttcctgtctg agcctgtccg ataacatctc gtccctccaa ggctaacgga
     2341 atggtcagct cctgaatagg agaggctttt tcaaagcctg ctgtaacaac agctgactga
     2401 atatcttctg ataagttaaa tgctgtaaat ttcaattgtt tctcttttct aaaaaggcag
     2461 tgcgaagctg ccttataaac cttttaatat tgtcgttcga ttaacaacct atttagtgta
     2521 acataattaa tattaaaaag ataggaaata agccatgaaa gtgtttttat ctcaaaatga
     2581 ttaacactat caggcagcta aattgataaa agcgtcactc cttattgctg attggctaac
     2641 agcctcaaaa aggcctcgtc ggacttgctt acctatgctt tttatctact ctgctaaaaa
     2701 gactcggcac agagacgagc cttcgcgatt ccatcaccaa tcttcaaaga cagcaattag
     2761 gattcctgaa agctccttat gccaatagcc tgccttttct tagcagcaga agtgcaaaaa
     2821 cggactaggt tcccctaatc cgcttagctg ctacattttt gcttctagct taacatctgg
     2881 gtatttatct gcaaaccaac gaagcgcaaa gtcattttca aagagaaaaa caggctgatc
     2941 aaagcgatcc cttgccaaaa tgtttcggct tgaggacatg cgttggtcca aatcctcctc
     3001 tgagatccaa cgaacagtct ttttgcccat tggtgtcatg atgacctctg cattgtactc
     3061 accctccata cggtgcttga aaacctcaaa ctgcagctga ccaactgcgc ccagcatgta
     3121 ttcacctgtc tgataattct tataaagctg aacagccccc tcctgtacaa gctgctcaat
     3181 acctttgtgg aaagattttt gcttcatgac attcttaggt gcaaccttca taaaaatctc
     3241 tggggtaaag gtcggcaatg gctcaaattc aaacaggttt ttactaacgc tcaaggtatc
     3301 tccaacctga taagtccctg tatcgtagac cccaataata tcaccggcaa ctgcattttg
     3361 gacattttca cgagactcag ccataaactg agtaacattt gatagcttaa cgcttttacc
     3421 tgtacgagac agctttacag ccattccctt ttgaaactct ccagagacaa tacgcacaaa
     3481 ggcaatgcgg tcacgatgct tagggtccat gttagcctga atcttaaaga caaagcctga
     3541 aaaatcctga ttgaggggat caatcatctg gtccgttgtc gtcttatgcc catgaggctc
     3601 tggtgcaaag gctaaaaagg tatctaaaaa ggtttgtacc ccaaaatttg ttaaggcaga
     3661 gccaaagaat accggagtca gctgaccatc taaaatagcc tgctctgaaa agtcattacc
     3721 tgcctcctcc aagagctcaa tatcttcaag cacctgctca taaaaagggt tgctggcaaa
     3781 aatccttgcc ccctcctcta aatcagcaaa cctctgctcc cccttataaa gctccaagcg
     3841 tttgttgtgc aaatcataca gaccttcaaa ggctcgtccc ataccaattg gccagttcat
     3901 ggggtaagaa gcaatcccaa gaacctcttc tagctcctcc aacaactcca aaggctcacg
     3961 tccatcacga tctaatttat taataaacgt aaaaacaggt atgttacgat gcttaacaac
     4021 ctcaaagagc tttttcgtct gtgcttcgat ccctttagcc gaatcaacaa ccatcacagc
     4081 agcatcaact gccattaagg tacgataagt atcctctgaa aagtcctcgt gaccaggtgt
     4141 atctaaaata ttgatacgct taccagcata atcaaactgc atgactgatg atgtgactga
     4201 aatcccacgt tgcttttcaa tatccatcca atctgactta gcaaattgac cagatttttt
     4261 tcctttaacg gtcccagcct cacgaatctc accaccaaaa taaagtaact gttctgtaat
     4321 agttgtttta ccagcatctg ggtgactgat aatcgcaaag gttcgacgct ttttaatttc
     4381 ttctgtaatt gacattcttt tttccttatt tgttcacatt gcagagcaag actctgatta
     4441 atagcttcaa gtcacacgtc acagttatgt ctacatgatc tcactcctaa atactgatat
     4501 gataaaaaga gctgctagag cagctccttt attatagctg attcgaagcg ctttttcaac
     4561 gccctatctt tctttagaga gcttcagctc taactgattg gcctcactaa atctcacata
     4621 gataagttca atcagcttaa ttaaaccagt caaccccatt gtcacaatga caaaattcat
     4681 aagcaggtga tgcgtatgaa taatcggaat atccatcaca aagccgtaat ttccctttgt
     4741 tgccaaattg atcaatacta aaacaaaatt aatggttgcc aagtaacggc aaacaaggac
     4801 tggctttagc tgacttggat tgtaaaaccg cagcaggtaa accaagccat tgaccaaaag
     4861 agcataatgc cccaggtaaa aagaaatatt agccacatgc catagctgat aagggtataa
     4921 atcaggtgat aacagggcca aaaaggtccc accaatccct aaaaccataa aaagctgctt
     4981 taagctactg cgatccggta agaaaaagat agctagcatg gccattcggc aatggtaaag
     5041 cggcaaagcc tctgtcaacg gaaagcctcg caaggcatac cagctataca aaccaaccaa
     5101 ttggaccaac tgaagcccta agaagatata gcgatacgac tttagctgat agagctgcag
     5161 ggtcataaaa accaaaaacg gcgctatcat caccgacaat agataaaata gcaaggacac
     5221 atgcggtagc ccaataggtt caattgcaaa aaaattcata aacatccctt tctacatttt
     5281 ttcattatac cttaatctta atgagaggac aagatgtttc atgtgttttt tctgaaaaag
     5341 tgttaggagg acttcccagc atgaggagct gtcaggcgat caaccacatt tgctagcagc
     5401 atggagtggc tgccctttag cagcatctgg tcattaggct caagaatagt caacaggtac
     5461 tggcacatgt cctcgtattg atcctctcga ttattctttt taaagaagct aactctgcca
     5521 cttggataat cttgactagc tagcttggcc aaggcttgaa tatcatcacc gtaaaagacc
     5581 aattgatcaa tacgcttggg atctaagctg gtaatcagct gagaatgcaa agcaactgag
     5641 tcagcaccta attccttcat atcagctaaa acagctattt ttttgccatt agggttggcc
     5701 ggaatggcag caaaggtttc caaaattaac cgcatagcag ttggattggc attgtacaca
     5761 tctgccaaaa ggtcggcgcc attagccgcc ttgacccact cggttcggtg gcgtgtcagc
     5821 ttgacggttt ctaaagcttc tataatatcc tcatcaggca cagccaagag tttaccaaca
     5881 taagctgcta tcatagcatt ggttgcattg tattttccag ttaagggaag agtgaccggt
     5941 cttggtaaga cattagtcct aaaggtcaag gagtccttgc actctttgat atcctcaacc
     6001 accagctctt gatgatcgcc aaagcgaatg accatctgac tatccggcaa atatggatca
     6061 aggataggat caccaggagc aattaaaatc ccgttagagt ccatcccatc aacgatttgc
     6121 attttccctt cggcaatctt ctcgcgagag ccaaagtagg ctaagtgagc ctcaccaata
     6181 agggttagca atgcaatatg aggtctggca attctagaga gcagctgaat gtctcccata
     6241 tgatcctgcc ccatctctaa aacaatcttc tcagtatcct ctggcatgtg aagcaccgta
     6301 taaggcaagc caatgtcatt attataattg ccctgggttt tgtaggtctt ataagctttt
     6361 gccaggaccg cttcaatcat atccttggtt gatgttttac cgtttgagcc tgttacagca
     6421 atgacatcga cacgtagctt atcaatataa tactgggcta atttttgaaa ggcagccaag
     6481 caattctcaa ctagtatata gggtctgcca ctgattgctc tttctgaaaa ggtagctacg
     6541 gccccatttt caaaggctaa gtcaataaaa tcatggccat ctcgctcacc ctgtagcggt
     6601 aaaaaaagat caccttttgt gatgtttcta ctgtcaaatt caatctgatt cagaggaacg
     6661 tcgtctaaat cagaaagact attttgagca tcaacaactc ttgccacttc atgtaatgtt
     6721 aatttcatct tatttttcct cttaaaacac tggtttttaa agctttgctt atattatagc
     6781 ataacatatt aggaatattc tt
//
LOCUS       DARYLJ010000074         6795 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYLJ010000074 DARYLJ010000000
VERSION     DARYLJ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6795
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(100..591)
                     /locus_tag="TU746_001837"
     CDS             complement(100..591)
                     /locus_tag="TU746_001837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892145.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYFDEGYSARQGINDLKS
                     LEN"
     gene            complement(778..3279)
                     /locus_tag="TU746_001838"
     CDS             complement(778..3279)
                     /locus_tag="TU746_001838"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL0892146.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            complement(3868..4731)
                     /locus_tag="TU746_001839"
                     /pseudo
     CDS             complement(3868..4731)
                     /locus_tag="TU746_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(5013..6530)
                     /locus_tag="TU746_001840"
     CDS             complement(5013..6530)
                     /locus_tag="TU746_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0892147.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
BASE COUNT         1928 a         1531 c         1232 g         2104 t
ORIGIN      
        1 ttctgaacca tttttcttat aaattatacc ttaataagct tccttaaaac atagactttc
       61 agttggatta ttttgataaa taataaatct gtctactgtt taattctcca gacttttcaa
      121 gtcattaatc ccttgtctag ctgagtaacc ttcatcaaag tacacacgat cctttatttt
      181 ctctatttct aacttatact tatttgaatt gaataaagcc tcatattctt tatcaaattc
      241 taaatagtca ttattcttat ttttagcttc tgatagaata gagctgattg cataggtgtc
      301 agtcaaagca tcaattctat cagcaaaatt ctttttctct ttatcactaa gcttactcaa
      361 ttctttaata ctatcttttg cttcattctt tctttgatca gaatagtctt ctgtaagggt
      421 acgacgtgaa taaggatttt tatttcttag gcgcaaatat ttccatgagt acccaccttg
      481 attccaaccg gtataattat atcttgaact attcgcactt actgttcctg tacttacagt
      541 tgctcctgct aatacaagtg ctgctgcact ggctaaaact aattttttca cgttgaaaaa
      601 tcctccattt attaaataag tttagggttt tattttacta ttatcttcaa gcttcttcaa
      661 tatcagtttt aatagcgtgt tacaaaacaa gaataaccac tcatgtaaac gagtggttat
      721 cagcttttta tagtattggg ctcaaaatta taaggaaggc attttttgct agggtcttta
      781 tttcaccaca atattaacga gcttattagg aacaacgatg acctttgcca cttccttgcc
      841 tgcaatttca gcctgtattt tatcatgtgc tagggctact ttttctagct cttctcttga
      901 gaggtctttt gccacgacaa gcttagcctt gacctttcct ttaatttgaa caacgatttc
      961 aacatcattt tcaacgagct tactatcgtc atgggttggc catgcaacat acgagatgga
     1021 ttgacctgaa gctgtcagga tctgccataa ttcttcacct aggtgtgggg caaatggggc
     1081 tagcaattga acgaagcctt tggcgtatgc cacataaagc tcgtcctctt tattggctgc
     1141 attgacaaaa atcatgagct gggcaatagc agtattgaat ttcatgcctt cgatttgttc
     1201 tgtgactgcc ttaacagtct catggtaagc cttatctaaa gctccgctat tttctgcaac
     1261 aatttccttt gtcgtgatca aacggtaaac acgatctagg aacttgcgtg ctccctcaag
     1321 gccttcttca gaccaagcaa tggacgcatc aagtggcccc ataaacattt catacacacg
     1381 cagggtatct gctccgtact gctccaccac atcgtctggg ttgacaacgt ttttcagtga
     1441 tttagacatc ttagcagggg cctgctcaag ctcctcgcct gtttccatgt ggaagaagct
     1501 accatcacgc ttgtcaacct tatccgttgc gaccaaggcc ccacgatggt cgcgatagct
     1561 ggttcccaaa atcatgcctt gattaaagag cttttggaag ggctccttgg ttggcactac
     1621 acccagatca tagagtacct tgtgccagaa gcgtgcataa agcagatgaa gcactgcgtg
     1681 ctcagcacca ccaatgtaaa tatctactgg cagccattgc tttaacaggt ccttatcagc
     1741 taattgctca tcattgtgtg ggtcaatata gcgaaggtaa taccagcttg agccagccca
     1801 ctgtggcatg gtgttggtct cacgacgccc tttgacccca tcctcgcggg tcacctcaag
     1861 ccagtcagtc aagttagcta gtggtgattc tcctgtacca gatgggcgaa tatccttggt
     1921 cactggcaaa acaagtggta ggtcctgctc aggaaccgct gtcgaggtac cgtcctccca
     1981 atgaatgatt gggattggct caccccagta gcgctgacga ctgaacagcc agtcacgtag
     2041 gcgataagag accttttcat gaccgacacc agtctcctcc agccacgcca ccattttagc
     2101 aatggcacaa gccttatcaa gaccatctag gaagtcagaa ttaatgtgaa taccgtcctc
     2161 tgtgtaggca gcctcatcaa cattgccccc ttcaagcact ggaataatct caagattgaa
     2221 ttgctttgca aatgcccagt cacgctcatc atgcgctggc actgccatga tagcacctgt
     2281 accgtagctt gcaagcacat aatccgcaat ccagataggc atttctttgc cattgaccgg
     2341 gttgatcgca taggctcctg tccagacacc tgttttttcc ttggcaagat cggtacgagc
     2401 aaggtcagat ttgaggctcg cttggcgttt gtactcagca acagcctgcg cttgctctgc
     2461 tgtagtaatg ctatctacta aggcgtgttc tggtgccaaa acagcatagg ttgcaccaaa
     2521 cagggtatca ggtcgtgtgg taaagacggt gaagtcttta tcggtatctt tgaccttgaa
     2581 ggttacatta gcccctgttg atttaccaat ccagttgcgc tgcatatcct tgatcgactc
     2641 tggccaatcc acttcctcca gatctgctag caagcgctct gcgtaggctg tgattttgag
     2701 catccattgg cgcatgggct tacggacaac tggatagcct ccacgctctg atgtgccatc
     2761 agggagaacc tcctcattcg caatagctgt tcccagctct tcaacccagt taacaggcac
     2821 ctcagcttca taggctaggc ctttttcata caattttgtg aaaatccact gtgtccattt
     2881 gtagtaacta ggatcagttg tattgatctc acgatcccag tcatacgaga agccaagagc
     2941 attgatctga cgtttaaagt tggcaatgtt ttctgctgta aactcagcag ggtcattacc
     3001 agtatccatc gcgtattgct cagcaggcag accaaaggca tcccagccca ttgggtggag
     3061 gacattataa ccctgtgcac gcttgaagcg gcttaaaata tcagttgcag tgtaaccctc
     3121 aggatgccca acatgaagac ctgcaccgga aggataagga aacatatcta aagcataaaa
     3181 tttaggcttt gaggcatctg tccccgtttt aaaggtatga ttatcagccc aaaaggcctg
     3241 ccacttaggc tcaatggctt tgtgattgta aaatgtcatg tgaattctcc catgtaaaaa
     3301 gtctagtctt cttattatag cacgatatca gacttttagg aatgggcaag caatattgct
     3361 gccacgacgt cggcatcaca aaaatgcatg taaccatttt ctagctgcat gcattttttt
     3421 aatctatgtt cagcggtttt gcattgcaat atcaccagtt tctcgattgc tatttgacta
     3481 tttcataaca tattgccaaa aaaactatac tgatgataaa aactcgctat gagaaagtgt
     3541 aactgtcttc atgcgtttgt cacgacattg ctaaagccct ttagactaga tagcgcgtct
     3601 ctgcgacgca taagctcaag ccttacgagc caactcataa aacagccaaa tatccgctat
     3661 catctcactt ggttttagat ctggtctagc tctagtttta agctctcaaa gaggtattga
     3721 gcttgaccaa ggagtgcttg ctaagctact aaaaagcccc ttatccttgc tatcagataa
     3781 gaagctcaat agagtttata ggaatgccaa tgtccattag taaaatgcta taaaacaata
     3841 gttaaagggg agagaattga gaatagctta atttttttgg cgttttggca tgactgttac
     3901 taggcctgca cttgtcataa tcgcaactgc agcagcagtg aaaaatggat ttgcagtagc
     3961 ttcacctgtt gatggtagct ggcctgctgg ttttgcggct ggcttacttg ctttttgctt
     4021 tgcaaccgag ttcgatgcct gaggagtctt agaacgaggc tgtgcctgat ccttaaactt
     4081 gtcagcaagc tcctgcttca agcgctcaat gttagcttga agatcagcat tgctacgatc
     4141 cttttgctca agcaggcttt gaagctcctt aaccttagcc tcaagctctg ccttgtctgc
     4201 cttaaccaca tcaagctcgg ctgttttttc agctaattgc gcttcaaggt cagccactct
     4261 attattagct gctgctacct cttgcccaag atttgatact cttgcattag cttcagcaag
     4321 tgcctgatct gccgcagctt tttcctttgc aagcttatca acattagcct tagcacctgc
     4381 cagctcctct tgaagtgttg tgatgttagc attagcagtt tcaaggtcag tctctgcttt
     4441 aaccttgtcc tgtgttaatt gatcaatctc agcaagcttc tctgtgagct cacgcttagc
     4501 agagttagtc aatcgaccca gactatcaac agcctgactt aaacgatctg cttctgcttg
     4561 agctactgag agtttgttgg caagatcggc agattcactg agagcattat cacgatctga
     4621 tgttacctct tccagtttag tgcttaattc tttagaagta agtttttctc tttctatatc
     4681 ggctttcaat tgagttgttt ctgctttcaa agtagcttca gagtcgatgc gagtctttaa
     4741 attcgctaaa agttttgagg aaataaaatt acttcctttg ataccaatag aagaattaat
     4801 ctttttatct aaactagggt tgatttacaa ctcttcatgt tgtttgtttc tcctttttat
     4861 ttttctcttt cccagaccaa agcacctact ccctaaggga attacacgtt ggcctatagc
     4921 tatattctac ctaattttat tggattaaca aagctcacta attttacacc atgacaagtt
     4981 gtggctattt taatgaaata taccgatatc tatcaatagc cgatgttccc aagcttgtta
     5041 gttgttttcg tttcaaagat actacccatt cgttttctta gataatggtt aagcttggcg
     5101 actataacgg ttggcacaaa tcgactaaag aaaaagatat cagcatgctc acagccccta
     5161 atgaccgtat cagtaataat gacgtcatag tcatgctgta gacacaaggc ttctatggtt
     5221 aatttatcaa aaatggtaat ctcaaaaaat tcaccaatgt attttttcaa aaagcttccc
     5281 gtactgccat gacttctttc tataatcaag agctttggtt ttttcatcaa ttcacacatg
     5341 gttaaaaaga aattctccca ggctatcagc aaggaataaa ccaaattgtt gagcaaatta
     5401 gtagcaagct ccatatcccc gtccttaaat agcctcttca cataatcggt aaacctaaaa
     5461 taaacatagg tataatgctc cttaaagaag gccaagtaat cctttttata atcgtaaatc
     5521 agaaagcttt cactaatatc ctccactcct aaaataacag tggcatgaag atatctggca
     5581 acctcatatt tatttggcaa tacaatacct gtagctccct ccatttcact aagcaaatct
     5641 atccagctca gcaaggactg aggacccgga acctcctcct taaccttatc tacctgcaag
     5701 gatttttcta ataccaaatc atcatctaaa taattggaaa acatttctga caagacaagc
     5761 tcatcaagcg gtactgaaaa tttaagcaca aacaaatgcg acagcttttt catctcctga
     5821 gaatcctgta acaactccaa tgaaagacta ctcagtgctt tatgcttccc aattttaaag
     5881 cctttgaggt agcgaatgag attaaccgca cttaatagct tgagttgacg aaaaatcgca
     5941 aaatcaatct taacctctat caaagatgcc attaattgaa caaattgctc atggtggttt
     6001 tcattaagta gagaagcaaa aggccattca gaaaaggtat atgcttctga aaaatacttg
     6061 atgtaaaaca gtctaatatt gtattcatct ccaactacac gaatgggctt agccgaaatg
     6121 ataatatcaa aatgctcttt taaatagaga ttggttttac gaatcaagcg ctttaaggtt
     6181 gacaagctaa taaaaagtgc ctctgcaaga tcatctaatg acgcaaaatc atcaaaaaac
     6241 aaggccgaca tcaactgaag agaaggagac tctagcaagg ctctccgata aacctccttt
     6301 aagccacttt gatgattgta atgaatatga aattgagaat ccttgtagaa cagcttgcct
     6361 aaatcttcca taaaaacaga attcgtgata cacgattgca gcgttaaaac cgaacaatcc
     6421 agcatctgac aagcatcttt ataatataat ggatttttcg tttcacttaa taaagtaatc
     6481 aactcaagct ctcgccactg ctgcttggta aagagattct ctatagacat ggtatctagc
     6541 tcctaaatat actcttcctg attaaaaact taccacaaca caacactatt tcattaactc
     6601 ttaatgtcgg ttgtagaaca gtattacatt atagcatact attagccaga aataccttag
     6661 aattgtttgc aaattaaccg attacaaata gacaaaagcc tttaaaacac aacagtcaac
     6721 tcattttttt attacattat aaattgtaga ctttttttat tttctcttat tttttagctc
     6781 tgccattact atcat
//
LOCUS       DARYLJ010000075         6164 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYLJ010000075 DARYLJ010000000
VERSION     DARYLJ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6164
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..446)
                     /locus_tag="TU746_001841"
     CDS             complement(<1..446)
                     /locus_tag="TU746_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892148.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
     gene            complement(443..862)
                     /locus_tag="TU746_001842"
     CDS             complement(443..862)
                     /locus_tag="TU746_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892149.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            complement(1247..2557)
                     /locus_tag="TU746_001843"
     CDS             complement(1247..2557)
                     /locus_tag="TU746_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL0892150.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVGQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
     gene            complement(2550..3224)
                     /locus_tag="TU746_001844"
     CDS             complement(2550..3224)
                     /locus_tag="TU746_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0892151.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKEFDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            complement(3643..>6164)
                     /locus_tag="TU746_001845"
     CDS             complement(3643..>6164)
                     /locus_tag="TU746_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL0892152.1"
                     /translation="LIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQVSFHQKD
                     LAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIYPSYYTK
                     DGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMPEVNAER
                     RKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTSLDFSLD
                     IAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDGNSTARS
                     RQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWRIFEDFQ
                     TTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRWIGDKDF
                     AAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTARVDNDQL
                     ILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNKGTLRFN
                     TENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAELVDLIAQ
                     LDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFEKRANES
                     DEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQIKYFEI
                     ADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQDLAAWY
                     SFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLAEYKAFF
                     EPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
BASE COUNT         1834 a         1322 c         1104 g         1904 t
ORIGIN      
        1 gctgtgatga gtgccagata gcctcccaga gagtgtccgg tataggagat ggcagcgtta
       61 gggtagcttg tcctaatgta gtcggaaaag gctttagcag tacttagctg actcttgact
      121 actttaaaag aatcaggctc ctcatgggta cacaggtatt gatcatctcc aaaaacaacg
      181 gattgaatat cggtgtcaat atcgcgtata tcactgctat ttgtcccggc ataggcaatg
      241 acgatatgac ttctatcctc tttgccatct tttattggca caacagccat agcctgcata
      301 ccattgtcgg ggttatcttc ggcttcaaga acgcggtatt ttccattggc aaccggatat
      361 ccttcttgaa tcggatctct ttctttacca gaatcaacct tatacacatc ctctgaaata
      421 tttttataat ctctatcaat catcatttct cctcgtaata aattgtttca acattagtca
      481 tattattcct catcttttca ctgtattgct taaattcttt tggagaataa taggaagtcc
      541 gtatttcttc acctaatcta tcttctgaaa aatgaatcag atatttctca ttaacaattg
      601 ttgttattga ccaagttccg gtggttgcag tttctaactg aaattctata aactcaattt
      661 ttgttatagg ctgaccatta catagctcta tatgctctcc tatgtatttc actaccctat
      721 cctgctcttg tctgtacttt ttctttttta gctcttcgcc attaagccaa ttcattgtta
      781 gtattcctcc taaaataatg attaaagcgg ctatgctgac taatttccag taatttttgt
      841 gttgctttag gtagactatc atgcttgtat tcctttatgc tttatcataa ggtgttgcaa
      901 gttttttgct tttacaaaaa cagctagaca ccagatattt taatattatg atacgattat
      961 aaatattata ctataataat ggtataatat cgacatattg ttggcaattt tttaccattt
     1021 tgacactttt atgagatttt ttatggtata tttttctata tctttgtttg atacctgcct
     1081 gtaatgcaag cctaataatg gttttattgg ctttaaacta tctattggaa ttttcttgtc
     1141 aactgcttgg tcaacagcaa aaagaagaca ataaaaaaag tcactagact tcttgatcta
     1201 gtgactgtta ttttcatact gattatgggc tagcaagaac tcagtgctat aattttactt
     1261 caaagatggc gccggtaggc ttattatcac tgacggtaat cgttcctttt aatgaggtaa
     1321 cgatctgctg cgctaaggcc aatccgagtc caaaccctcc tttttggcgt gcccttgcct
     1381 tatccactcg gtaaaagcga tcaaaaatct ttttcttatc atcatccttg atccctgggc
     1441 cattatcaat aacagaaatc aataaatgct tatcggtcgt tctaaccttg acctcaacca
     1501 caccgttatg atcagtgtat ttgatcgcat tatcaaacaa aatggtcatc agctgcttga
     1561 gcaaagcctt atccgtcttt aagggcctat tgatctgatt aactgagata aactgcttgc
     1621 ctgactcttc tgcaactaat tgataatttt caaaaacagt atcaaaaaag gctgcatcaa
     1681 catcaactag ctgcggcttg atcccatcat cacttctggc taaatttaac agattagttg
     1741 ttaatattct catattacga acctcatcta ggcttgacgc aatatgctcg ctattgtcta
     1801 aaatggtttc gttaggcttt ctaaacagcg attccaaacg attttgcagc accgctaaag
     1861 gagtcctaag ctcatgactg gcattttcta caaacatttt ttgcttggca tagctctcca
     1921 taattggctt tctgctccac ttagccaaat aaatactggc caaaatcgaa attaaccaaa
     1981 agacaatcat aaccatgata ataatctgtt catagcgctc attagcagta tccagctgct
     2041 gaacattaac cactgccatc atataagcca ctgctggata gtttttaatg tgaaccttaa
     2101 cggttagggt atggtatttc tccttttgcc cataaaaatt catcagctgt gtggtgacaa
     2161 tgttattgag ctggcttttg tctaaacgaa agctttggta attagagaaa gcgtcaaagg
     2221 agttcaatat cgtcccatta gcactaaata aaataatatc catattagtg gtggaggagc
     2281 caagtgattt tgacgcttcc agttcaggaa gagcctgaat aaggttattt tctgcatcaa
     2341 aataaaagga agatattctc gccatggtcc tattagcata gttgctggca ttttgaccga
     2401 ccgaaatgag actgctgtct actgtggaat agacactaaa cctcatgatt tgtaaaataa
     2461 tgatggtcat gacaacaaaa atgcctgtaa aaatagcaaa gaaatgaaaa aaatgcgtat
     2521 aattatcgga caataatcct ttttttagtt tattcattag cttttaagat atatcctaca
     2581 cttctcaagg tttgaagatg attaacaaag tctgtcccct taagcttctt acgaatttta
     2641 gagacataga cctctacaac agagatagtg gtatcactat caaagcccca gatacgatca
     2701 aaaatttgtg attttggcaa aataacattt tgattttgaa ggatatagat tagtaaatca
     2761 aactccttgc ctaatagctc tatggcctgc ccattgacct gtacctcttt acgggtagta
     2821 tctacagtca ggttgccaaa tttaaggctc ttgtcattaa actttcctac gcgcttaagc
     2881 aaggcctgaa tccgcatttt taattcttct aggtaaaagg gcttggttaa atagtcatca
     2941 gcaccaagct caaagccatg ccctttgtca tcgatgcttt ctttggcagt catgatcaag
     3001 acgggaattt tgatgtcttt ttcacgtaag gcttttaaca cttgaaagcc atccttttca
     3061 ggcagcatca aatctaacag aatcaaatca taaataccgc tttctgcctc atagagtcct
     3121 tcgtcaccat caaaaacctg cgtcacatca gcaaagtcat ctaaaaaatc aaagatagaa
     3181 tttgacaagc ttaaatcgtc ttctactaat aatagtttta tcattatgat acctcaattc
     3241 tctaaagact aacagcctcg ctcaagtagt ctttagggat taccttacta aatgaattct
     3301 ctaatctaac gataacacaa aaagcttaag ctttgctaaa ctattgctca tgacaggtca
     3361 taagcataca gttagtctgg agacctactt aagttataaa actgacagac aaagaattgt
     3421 ctctatgacc tatccgtcct aagctctgac tctgatcaac tagtaattta cggcgctaag
     3481 attaaccact gcttatgatt gaagcctcct catttgccaa aagctgacag gcagtgccac
     3541 taagctacag caattaccct ttgatctaaa tgttacttaa agatagtagc tttgacacca
     3601 ataaaggagt tgaggatggt ccccagctcc tttgtgatat cattagtact gacttaaagc
     3661 attagcgata gcttcctttt cactatcaat gagggcaact cgagctgaaa tttcatttat
     3721 ccccatcgaa atattgcgac taatcgccat atcatcaagc tgtggctcaa agaaggcctt
     3781 atattcagct aaacgctctg ctgttttaaa atggttagca gggtaaataa taaacttgtc
     3841 aaagctcata tcaccaccca gtgaagcctt aatccacttc caattttctc tagcccaacg
     3901 ccaaatgctt tcttgtgcag aggcctgatc aagcaaaaag ctgtaccaag ctgctaagtc
     3961 ctgtggctta ataatatcct tatcctttaa gctgtactga atgcgcttaa gagttgatgg
     4021 attagctgtt gttgctaagg cggcgctcaa atcagctcga agattgttgt ccttggttgc
     4081 aacataagca tcaaaataag catcaaccaa gtcagctatt tcaaaatact tgatctgact
     4141 caccaatacc gagcggcgaa tggctgctgg aatggcttcg atacgatttg cataagcttc
     4201 aaagatagtc ttggcctgct tgatcacatc acgattgcct ccaaccaaca ggtgatgtaa
     4261 agcaatttga cgaaccattt catcttcatc agattcattt gccctctttt caaatccaag
     4321 ctgcctgaag tcctcttgga aaatagaaga aatcaatcga ttgaaggact gctctgctga
     4381 ggttccttca tcaatgaact gctctaagcc tctaataacc tgctgaacag ctgcagcaac
     4441 catataggat tttttgtcat ctagctgagc gattaagtca accagctctg cataagaaat
     4501 cagaccgcta tcagccagca agcggcgctc ttgaatcact tgaagggcag aggtgttgtc
     4561 aagatgcttc aaatcatcaa ctaagctatg aaagagctgt ccctgataat ctgtaatgta
     4621 atgcgctgta ttttctgtat taaagcgaag tgttccttta ttttgggcgg ctaattgact
     4681 aaagcctgaa ataacgatgg actcctctgt cagtacgtca ggaagacctt tccagttcgc
     4741 atttagtgga attggccata gtctcttttg gtcgcttgcc tcaccaataa agaactgctt
     4801 ttggctgaga atcaactgat cattgtcaac tctggccgtt aagacaggat agcctggctg
     4861 ctctagccaa gcgtccataa acgcagcaac atctttacca gaagcttctg aaagagcctg
     4921 ccacaaatca cgtcctacag tattacggta ttgatgcttt tcaaagtaaa ggcgcagacc
     4981 tgccgcaaaa tccttatcgc caatccagcg acgaagcata tgcattaagc ggctaccttt
     5041 ggcatagaca atagctggat caaacagggt attaatctca tctgggtgat taacagcaac
     5101 atggactgat tgaacaccgt ctgttgcatc acgcttaaga gccagcggca cacctgttgt
     5161 ttggaaatcc tcaaaaatac gccatgacgg ctcaatagca ttgatggcta catattccat
     5221 catattggca aagctttcat ttagccaaag atcgtcccac catttcatgg ttacaagatt
     5281 accaaaccat tgatgggcaa tctcgtgtgc cacaacaaga gcaacatttt gtctgctgcg
     5341 ggctgttgaa ttgccatcaa ccaacaggta aatttcacga taggtaatca agccccagtt
     5401 ttccatcgct ccagatgaaa aatcaggaag agcaatattt agagattgcg gaataggata
     5461 gcgaacccca aagtagtctt cgtaaaaatc aatgacacgt acagcaatat ccaatgaaaa
     5521 atctagcgag gtcagtgggt gagccttggt tgcataaaca ccaactgttg tcccgttttt
     5581 actttttgtt gttttgccat gcaagtctcc taaggcaaag gccagcagat aagaagacat
     5641 tctaggagtt gtctcaaagg tccaaagacc ggtctccttg cggcgctcag cattgacctc
     5701 aggcatattt gatagagcaa tctcgccctc tgcttggtca aatgtcaagc ttaagtcaaa
     5761 ggtagccttt gcttcaggct cgtcaataca tggaaaggcc tcacgcgcaa aatggctttc
     5821 aaactgcgtt gaaataacct cctgtttttc accatctttt gtgtaatagg acgggtaaat
     5881 accagtcata ttgtcagtaa tattacctga aaattcaatg acaagcgtca tcataccagt
     5941 ctctggcagc tcaacacgca caagctcatt gtcatcgtca acatgatagc taacagcttc
     6001 attgtcaagt aaaatggcat tgattgccaa gtccttttgg tgaaatgaca cttgattatc
     6061 taatgcttca ccattgattg caacattacc tgtgaaggtt tttgtgctgc gattaatgtc
     6121 taagaaaata ttataatttt caggaataaa cttttcaata agat
//
LOCUS       DARYLJ010000076         5363 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYLJ010000076 DARYLJ010000000
VERSION     DARYLJ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5363
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            9..1430
                     /locus_tag="TU746_001846"
     CDS             9..1430
                     /locus_tag="TU746_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL0892153.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHNFDAIVYKLHGDVETPE
                     DAVITRSDYEEFGYNKRKLFREVLEGDLLTKTFLFLGFSFEDPNFNYVIGRLRVLLDE
                     KNTRKHYCIMKRVQDADEDYEYKKARQELQIEDLNRYGIFTYLVNKYDEITEILSTLV
                     DRFRRKTIFISGSAYSYSAYSQKTGENFIHKLSFELSKNGYHIVNGYGKGVGEFVLNG
                     VADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKLYKENREQMIESCGIAIFLFGNKEA
                     EDIASGVMDEYELSKKHGLVCLPIEYTGGASKEIYDQTTQEISDKNTISAIEQANKQC
                     DGDIDMSVKNIVQAVKILNKEEF"
     gene            1431..1928
                     /locus_tag="TU746_001847"
     CDS             1431..1928
                     /locus_tag="TU746_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL0892154.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     KTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSKYVYSDIKDNIEGLIEYGINH
                     KPSTW"
     gene            complement(1952..2350)
                     /locus_tag="TU746_001848"
                     /pseudo
     CDS             complement(1952..2350)
                     /locus_tag="TU746_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2430..3635
                     /locus_tag="TU746_001849"
     CDS             2430..3635
                     /locus_tag="TU746_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0892155.1"
                     /translation="MEYIERPKYLNHIEKFVDKPIIKILTGMRRVGKSTILMMIKDEI
                     LKHVPDEQKIYINFESLEFMSINEASFLASYISEKSKNLSGKLYYFFDEIQLVNNWEK
                     VVNGLRVDQDCDIYITGSNSNLISGELATLLAGRYIEFEIQPFTFGEFLKIFSDSNLT
                     KEALFDKFIKLGGMPILKYFKLEEDSSYKYLSDVYNTVLVKDVLNYNKIRDVDIFNRI
                     LSFAIENIGSTFSANSIKKYLKNESRGVSVDTILNYLEYCNRAFILKKVQRFDTVGKK
                     KLKVDEKYYLTDHGFRQARGYSNTKDIERTLENIVYIELVSRGYRVEIGKVKDLEIDF
                     IASKDNERLYYQVSYLMETEETRKREFGVYDFVRDNYPKFVLSMDKVDFSQNGIIHKN
                     VIDFLLESK"
     gene            3873..4040
                     /locus_tag="TU746_001850"
                     /pseudo
     CDS             3873..4040
                     /locus_tag="TU746_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            complement(4471..5115)
                     /locus_tag="TU746_001851"
     CDS             complement(4471..5115)
                     /locus_tag="TU746_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0892156.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
     gene            complement(5134..>5363)
                     /locus_tag="TU746_001852"
     CDS             complement(5134..>5363)
                     /locus_tag="TU746_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892157.1"
                     /translation="LGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLL
                     CLTIVGIPFARQSLKLAKISLFPFGAIIYDI"
BASE COUNT         1937 a          690 c         1046 g         1690 t
ORIGIN      
        1 gggaggaggt gtttattatt aaaggtgaag tatccagaaa agatttgatt agagaaattg
       61 aaaaagctat taaaagtgat gaattaggag catttattgg agcaggatta tcaattcctg
      121 ccggattttg tagttggaaa gaacttctaa gagaacctgc agaagaaatt ggattagatg
      181 ttgaaaaaga aagtgatttg gttaacttgg ctcagtatta ttctaattca aaaaagagaa
      241 catcaataga tgacttgatc aaaggtcaat tttctcaatt agtaaagcct actgaaaatc
      301 ataaattatt gtcgcagctg cccatttcaa ctttttggac aacaaattat gataagttaa
      361 tagaaaaagc tttagaaaat aatatgaaaa agccttatgt aaaaacaaag gatgaacaat
      421 taagaggtac aaatcataat tttgatgcga tagtatataa gctgcatggt gatgtagaaa
      481 ctcccgaaga tgcagtaata acaagaagtg attatgaaga gtttggatat aacaaaagaa
      541 aattatttag agaggtttta gaaggagatt tgcttactaa aacatttcta tttttgggat
      601 ttagttttga agatccaaat tttaactatg taattggaag gttaagggtc ttactcgatg
      661 aaaaaaatac aagaaaacat tattgtatta tgaaaagagt ccaagatgct gatgaggatt
      721 atgaatacaa aaaagcaaga caggagctac aaattgaaga cctaaataga tatggtattt
      781 ttacatattt agtaaataaa tatgatgaaa tcaccgaaat attgagcact cttgtcgata
      841 gatttagaag gaaaacaata tttatatctg gtagtgcgta ctcctattcg gcttattctc
      901 agaaaactgg cgaaaatttt attcataaac tatcttttga actatcaaaa aatggttatc
      961 atattgtgaa tggatatggt aaaggagtcg gtgaatttgt attaaatgga gttgcagatt
     1021 attgtttgac tcacaagtcc aaaataaatg attttttaac acttatgcct tttcctcaaa
     1081 atagttcatt aggtattgat ttagataagc tatataaaga aaatagagag cagatgattg
     1141 aaagttgtgg tatagctata tttctttttg gtaataagga ggcagaagat attgcaagcg
     1201 gagttatgga cgaatatgag ttatcaaaaa agcatggatt agtatgtttg cctattgaat
     1261 atactggcgg tgcatctaaa gaaatatatg atcaaacaac tcaagaaatt tcagataaaa
     1321 atacaataag tgcaattgaa caggcaaata aacaatgcga tggcgatatt gatatgtctg
     1381 ttaaaaacat agttcaagca gttaaaatat taaataagga ggaattttaa atggcaaaaa
     1441 gacaggtatt ttttagcttt cattacgaca atgataattg gagggcagga caggttcgca
     1501 atatggggaa agtagacagt agttctacct tttctgataa tgactgggag gaagtaaaag
     1561 aaaaaactga aagtaaaatt aaagaatgga ttgatgaaca gttaaataag cgttcatgtt
     1621 tggttgtttt gattggagaa aaaacagcga acagaaaatg gataaattat gaaataagaa
     1681 aagcatatga gttaaataaa ggtattgtgg gaatttatat tcacaagttg gagaattcac
     1741 tgggagagca agatgataag ggtaataatc cttttgatta tttaacatta gaaggtgaaa
     1801 aactttcaaa gtatgttaaa tgttttgact ccaactattc atcaagtaaa tatgtttata
     1861 gcgatattaa agataatatt gaaggtttaa ttgagtatgg aataaaccat aaaccatcaa
     1921 cttggtaata aatgatgatg gagagaaaaa attatctctc catctcctta cccatgtaaa
     1981 ttccataatt ttttcgtatc ttgtaaagtt cgtccataat agattttgag gaagaatact
     2041 cttgcataag ggtattcttt ttttcttgca atttatcaag tctatctaaa atacccttag
     2101 aatttggcaa cttggaatat gattttttaa gctctgaaag ggcattttca tataaggtaa
     2161 tctgagcttt gtactcttca aaaaatgcct tgtcagatgg acttgcctta tattctttgt
     2221 agtattgcct gtatttttta acagtgtgaa cttgctccat agtggcagaa agctcctgca
     2281 tttccttatc aatagccttg atcttatcct gtaaattttg cctttcatcg gctgctttta
     2341 tgatatattt cgattatatt cgaaaacaat attggaaaat atatttttat cgtgtataat
     2401 ataatcaaag ctaaagagag gtgaatgata tggaatatat tgaacgaccc aagtatttaa
     2461 accatataga aaaatttgtt gataaaccta ttattaaaat cttaactggg atgcgaagag
     2521 ttggaaaatc taccattctg atgatgatta aagatgaaat tttgaaacat gtgccggatg
     2581 agcaaaagat atatatcaat tttgaatctt tggagtttat gagtataaat gaagcgagct
     2641 ttttggcaag ttatataagt gaaaagtcaa aaaatctaag tggtaaatta tattatttct
     2701 ttgatgaaat acagttggta aataactggg aaaaagtagt taatgggtta agagtagatc
     2761 aagattgtga tatatacatt accggttcaa attcaaattt gatttccggt gaacttgcca
     2821 cacttcttgc aggaagatat atagaatttg aaatacagcc atttactttt ggggaatttt
     2881 taaagatttt tagtgattca aatctaacta aagaagcact ttttgataaa tttataaaat
     2941 taggtggaat gccgatttta aaatatttta agttagaaga agatagcagt tataaatatt
     3001 taagcgatgt atataatact gtcttggtta aagatgtgct taattataat aagatacgag
     3061 acgtagatat atttaacagg atattatctt ttgctattga aaatatcgga tctacttttt
     3121 ccgccaacag tataaaaaag tatttgaaaa atgagagcag aggagtatct gttgatacaa
     3181 ttttaaatta tttagagtat tgtaatagag ctttcatact aaaaaaagta caaagatttg
     3241 atactgtagg aaaaaagaag ttaaaggttg atgaaaaata ttatcttaca gatcatggat
     3301 ttaggcaggc aagaggatac tccaatacaa aggatattga aagaacattg gaaaatatcg
     3361 tttatattga acttgtttca agaggatata gagttgaaat cggcaaagta aaagacttgg
     3421 aaattgattt tattgcaagt aaggataatg aaaggttata ttatcaggtt tcttatttga
     3481 tggaaacaga agaaacaaga aaacgagagt ttggtgtgta tgattttgtt agagataatt
     3541 atcctaaatt tgtcttatcc atggataaag tggattttag tcaaaatgga attattcaca
     3601 aaaatgtgat tgacttttta ttggaaagca agtagttgtt tccttaaatg tttgcatact
     3661 attcaaaaat taaatataag ttataagaga caatggaaaa agaaaaaatc taccgtcttt
     3721 tttgtgttta aaaaggagga tatagatgat aaggattaga agttctaccg aaataaaaat
     3781 aaaatagtag aagtatcagc gattggaaaa agtccagtcg cttttttaat gggaatttta
     3841 aattaaaaaa ggagaaaaat tatggataaa aaatgattaa tattaacgca aatttagtag
     3901 cagaatcaat ttactcaagt tttgaaagag aaggagaaga agtataagtt gtaaatttta
     3961 catttgtaaa gaagtacggt aaaggcaagg agtacatcaa ctgtgcagct tatggagaaa
     4021 aagcagaact gaaaaaggag aggacaaatg aaaaccagtt tgaaatggat gaaagatttt
     4081 tagcaagaaa agaaatcttt ctgaatttta atgttcctat atttcaatga gctgtattgt
     4141 tttgtataga tgttactaca agaaaatcat tgaaaatatc tgctgtagtc tctactatca
     4201 tcaggaaata actgttttgc gcgtttgtcg tggttgaaag ccttggtcgg cttgataaat
     4261 gataaaaagg actgagtcct gttcgataca gaattcaatc cttttttgaa atacattgtc
     4321 aaacttttga gcttgtccaa tttagtcctc tcgtgtattt agcttttcat aacttcctac
     4381 agctaataaa gcgtccctca aaaaatgaga tgtgttctct aaccaatgga gtacagttta
     4441 gctgtcttgg agctttgtgc ttaagagcta ctagggtgtt aatctagtag tctttttttg
     4501 taaaaatgat gtatcattcc accttagaca atgaaagtgt ttgaaatcca aggtttctat
     4561 aacggttagg ctggcattat ccagtcctcc ctgtgcccga agcatacctg gctcaaagcc
     4621 taaaagagca cgaatagaag ctgtcaaatg ggcgccatgt cctaccatta aaacctgctg
     4681 ataggcctta tcttccaaac ttttaatgag ctgataaagc ctttgtgtgc tttcataaag
     4741 ggattcagcc ttaaattgac tgggcttgaa tttggctaaa ttgtgataaa aggctgacat
     4801 ctgactgggg tagatggcgg atacagttgc tattttggtt ccttccaggg tgcctaggtt
     4861 ccattctctc agctgcttgg tataactaat atcagtcttg cagttagctt cgtccacaat
     4921 aatgcgagca gtatcaacag ctctttttag gtcgctggag tagatcgcat caaaagaaat
     4981 gtcccacagc tctcttgcta gctggcgcaa atcgtcctta gagctttcaa gcaagggcga
     5041 atctccgtta gctccctgaa aacggccctc taggttccac aaggttttac catgtctgac
     5101 aaaatacaat ttcataagtc ttttgcttcc taattaaatg tcataaatga tggctccaaa
     5161 aggaaagagg ctaatcttgg ccaattttag agattgccgg gcaaatggaa tgccaacaat
     5221 cgtgaggcac aagagaaggg cagaagtcaa atgcatgatc gctaagctcc agccacagca
     5281 gacaatccag atgatattga gcagcaggct gcctgctcct tggccaattt cgatggcttt
     5341 tccaaaagga aaaagaccca aag
//
LOCUS       DARYLJ010000077         5331 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYLJ010000077 DARYLJ010000000
VERSION     DARYLJ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5331
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            90..1643
                     /locus_tag="TU746_001853"
     rRNA            90..1643
                     /locus_tag="TU746_001853"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1865..1937
                     /locus_tag="TU746_001854"
     tRNA            1865..1937
                     /locus_tag="TU746_001854"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1898..1900,aa:Ala,seq:tgc)
     gene            2245..5144
                     /locus_tag="TU746_001855"
     rRNA            2245..5144
                     /locus_tag="TU746_001855"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5229..>5331
                     /gene="rrf"
                     /locus_tag="TU746_001856"
     rRNA            5229..>5331
                     /gene="rrf"
                     /locus_tag="TU746_001856"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1525 a         1083 c         1543 g         1180 t
ORIGIN      
        1 aagacgacct aaacgtgcgg gttacggaag taacctgtca ataaagaaac aagtcagtaa
       61 tgacgtcgag ttaagagctc aaacactgaa ttaacgagag tttgatcctg gctcaggacg
      121 aacgctggcg gcgtgcctaa tacatgcaag tggaacgcac agatgatacg tagcttgcta
      181 caattatctg tgagtcgcga acgggtgagt aacgcgtagg taacctagct tatagcgggg
      241 gataactatt ggaaacgata gctaataccg cataaaagtg gttgacccat gttaaccatt
      301 taaaaggagc aacagctcca ctatgagatg gacctgcgtt gtattagcta gttggtaggg
      361 taaaggccta ccaaggcgac gatacatagc cgacctgaga gggtgaacgg ccacactggg
      421 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggggg
      481 gaaccctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
      541 gttagagaag aacagtgatg ggagtggaaa gtccatcatg tgacggtaac taaccagaaa
      601 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
      661 tttattgggc gtaaagcgag cgcaggcggt ttgataagtc tgaagttaaa ggcagtggct
      721 taaccattgt atgctttgga aactgttaaa cttgagtgca gaaggggaga gtggaattcc
      781 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
      841 ggtctgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
      901 tagtccacgc cgtaaacgct gagtgctagg tgttaggccc tttccggggc ttagtgccgg
      961 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1021 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1081 cttaccaggt cttgacatcc cgatgctatt cttagagata agaagttact tcggtacatt
     1141 ggagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     1201 caacgagcgc aacccttatt gttagttgcc atcattaagt tgggcactct agcgagactg
     1261 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     1321 ggctacacac gtgctacaat ggttggtaca acgagtcgca agccggtgac ggcaagctaa
     1381 tctctgaaag ccaatctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     1441 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     1501 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg ttaaggagcc
     1561 agccgcctaa ggtgggatag atgattgggg tgaagtcgta acaaggtagc cgtatcggaa
     1621 ggtgcggctg gatcacctcc tttctaagga aaaaggaagc acgtttagcg tcttatttag
     1681 ttttgagagg tcttgaaata agtcatgaga acgttaagaa acccgtatga caatagggaa
     1741 ctgacgcaga gtcgtaggac tcaaggaagt gattcttttt cactagggtt ttagttcgaa
     1801 tacagtttgg cttcatacag accattgata agagtataca tatacaagta catttatagt
     1861 gtacggggcc ttagctcagc tgggagagcg cctgctttgc acgcaggagg tcagcggttc
     1921 gatcccgcta ggctccatta tctaggatac aaagagaagt ttgggttacc taattttctg
     1981 tattctaaga tatataagat atagttcaag taattgaaca cgacctcatt ttttaggaaa
     2041 aaagataaat ctcctcgtgt gtaaagcaca catcgtcgat ttcctatttt tctacaaaaa
     2101 tgcccaacaa gttgggacgg tcttagtatc ttaatcttgt ccattgaaaa ttgaataact
     2161 atatcatatt ccgcaatcaa aaaagattgt aagaaagtaa caagaaataa accgaaacgc
     2221 tgtgataacg agtttaaaaa ataaggttaa gttaataagg gcgcacggtg gatgccttgg
     2281 cactagaagc cgaagaagga cgtgacaaac gacgaaatgc tttggggagc tgtaagtaag
     2341 caaagatcca gagatgtccg aatgggggaa cccactagct aatggctagt atccataact
     2401 gttaaggtta tgagaaggaa gacgcagtga actgaaacat ctaagtagct gcaggaagag
     2461 aaagcaaacg cgattgcctg agtagcggcg agcgaaaagg caggagggca aaccgaagag
     2521 tttactcttc ggggttgtag gactgcgctg tgggacgaca agattataga agaaggcctt
     2581 gggaagggtc gccaaagaga gtaatagcct cgtattcgaa atagtcttta accctagcag
     2641 tatcctgagt acggcgagac acgaggaatc tcgtcggaat ctgggaggac catctcctaa
     2701 ccctaaatac tcactagtga ccgatagtga accagtaccg tgagggaaag gtgaaaagca
     2761 ccccgggagg ggagtgaaag agaacctgaa accgtgtgcc tacaagaagt tcgagcccgt
     2821 taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttta tgtgcgaggt
     2881 taagttgaag agacggagcc gaagggaaac cgagtcttaa tagggcgtaa gtacgtggac
     2941 gtagacccga aaccatgtga cctacccatg agcaggttga aggtgcggta agacgcactg
     3001 gaggaccgaa ccagggcacg ttgaaaagtg cttggatgac ttgtgggtag cggagaaatt
     3061 ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta gcgtcgatat
     3121 gaagtctctt ggaggtagag cactgtttgg gtgaggggtc catcccggat taccaatctc
     3181 agataaactc cgaatgccaa tgagatatga tcggcagtca gactgcgagt gctaagatcc
     3241 gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc cccaaataac tgttaagtgg
     3301 aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc tattcattca
     3361 aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa
     3421 acagtttacc gaagctgtgg attaccgtta aggtaatggt aggagagcgt tctatgtgtg
     3481 atgaaggtat actgtgaaga gtgctggaac gcatagaagt gagaatgccg gtatgagtag
     3541 cgaaagacag gtgagaatcc tgtccaccgt aagactaagg attccagggg aaggctcgtc
     3601 cgccctgggt tagtcgggac ctaaggagag accgaagggt gtatccgatg gacaacaggt
     3661 tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa ctaaaccgga
     3721 cgactggaag agtccggcta agcagtgagg tgtgatgtga gtcaaatgct tacatctata
     3781 acattgagct gtgaagggga gcgaagttaa gtagcgaagt tagagacgtc acactgccaa
     3841 gaaaagcttc tagcgatacg tatactctac ccgtaccgca aaccgacaca ggtagtcgag
     3901 gcgagtagcc tcaggtgatc gagagaactc tcgttaagga actcggcaaa atggccccgt
     3961 aacttcggga gaaggggcgc tgactgaagg tcagccgcag tgaataggcc caagcaactg
     4021 tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg tgacgcctgc
     4081 ccggtgctgg aaggttaaga ggagtgctta gcgcaagcga aggtatgaat tgaagcccca
     4141 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
     4201 ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac tcggtgaaat
     4261 tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt
     4321 actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga gccatagaag
     4381 tcgggacgcc agtttcgatg gaggcgatgt tgggatacta cccttgtgtt atggctactc
     4441 taacccggat aggtgatccc tatcggagac agtgtctgac gggcagtttg actggggcgg
     4501 tcgcctccta aaatgtaacg gaggcgccca aaggttccct cagattggtt ggaaatcaat
     4561 cgcagagtgt aaaggtataa gggagcttga ctgcgagagc aacacctcga gcagggacga
     4621 aagtcgggct tagtgatccg gtggtaccgt atggaagggc catcgctcaa cggataaaag
     4681 ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg gaggtttggc
     4741 acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc
     4801 gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
     4861 cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac cagagtggac
     4921 ttaccgctgg tgtaccagtt gtctcgccag aggcatagct gggtagctat gtagggaagg
     4981 gataagcgct gaaagcatct aagtgcgaag ccctcctcaa gatgagattt cccataacgt
     5041 taagttagta agagccctga gagatgatca ggtagatagg ttaggagtgg acgtgtggtg
     5101 acacatggag cggactaata ctaatagctc gaggacttat ccaaaagatg aaaccagtcg
     5161 ctattgacag cttaaggaat tcttgttaga ctatagttat tcaattttga gtggagaaga
     5221 ctcgtaagtt aagtgacgat agcctaggag atacacctgt acccatgccg aacacagtag
     5281 ttaagcccta gaacgcctga agtagttggg ggttgccccc tgtgagatac g
//
LOCUS       DARYLJ010000078         5325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYLJ010000078 DARYLJ010000000
VERSION     DARYLJ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(150..389)
                     /locus_tag="TU746_001857"
     CDS             complement(150..389)
                     /locus_tag="TU746_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL0892158.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TU746_001858"
     CDS             complement(548..1036)
                     /locus_tag="TU746_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0892159.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TU746_001859"
     CDS             complement(1055..1345)
                     /locus_tag="TU746_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL0892160.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TU746_001860"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TU746_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL0892161.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5325
                     /locus_tag="TU746_001861"
     CDS             4640..>5325
                     /locus_tag="TU746_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL0892162.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDT"
BASE COUNT         1622 a         1165 c         1062 g         1476 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatac
//
LOCUS       DARYLJ010000079         5250 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYLJ010000079 DARYLJ010000000
VERSION     DARYLJ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5250
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            84..659
                     /locus_tag="TU746_001862"
     CDS             84..659
                     /locus_tag="TU746_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL0892163.1"
                     /translation="MKKVINTILLAACFLFFLGNFTTNVLAEGINDKIENGTESDISF
                     QNGELLKNYLILEGERVYFDYDRATQDKVSDDVLEMGMLVEAISKDYSEKTFTPDKYF
                     KASWPIHGNYCGPGHNGNNFTLPVVDVLDQGCQNHDSCYKWGAGIGANCECNRQLVNY
                     IKVYRRWMPANVLGVADAIRVYFETVGSIGC"
     gene            1008..1190
                     /locus_tag="TU746_001863"
     CDS             1008..1190
                     /locus_tag="TU746_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0892164.1"
                     /translation="MLTYDEFKQAVDNGYITGDTVTIVRKNGQILDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            1388..1777
                     /locus_tag="TU746_001864"
     CDS             1388..1777
                     /locus_tag="TU746_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL0892165.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            1774..2985
                     /locus_tag="TU746_001865"
     CDS             1774..2985
                     /locus_tag="TU746_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL0892166.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            2998..4344
                     /gene="asnS"
                     /locus_tag="TU746_001866"
     CDS             2998..4344
                     /gene="asnS"
                     /locus_tag="TU746_001866"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL0892167.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            4644..>5250
                     /locus_tag="TU746_001867"
     CDS             4644..>5250
                     /locus_tag="TU746_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0892168.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDSGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEVGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPKG"
BASE COUNT         1547 a         1007 c         1287 g         1409 t
ORIGIN      
        1 ttagttttaa gaaaggaggt ttgttgacat attggggtag cacttaatag tttctctgtt
       61 attaaaatag ttggagaaaa tttatgaaaa aagtaataaa tactattcta ttagctgctt
      121 gttttttatt ctttttaggt aattttacta caaatgtatt agctgaaggg ataaatgata
      181 aaatagaaaa tggcactgaa agcgatatta gcttccaaaa tggtgaactc ctaaaaaatt
      241 atcttatcct agaaggtgaa cgagtatact ttgattatga tagagcaact caagataaag
      301 tatcagatga tgttctagag atgggaatgt tagttgaagc tataagtaag gattattctg
      361 agaagacatt caccccagat aaatatttta aagctagttg gcctatccat ggtaactatt
      421 gtggaccagg tcataatggg aataacttta cgttgccagt agtagatgtt ttggatcaag
      481 gttgccaaaa ccacgatagt tgctataagt ggggtgccgg tattggtgct aattgtgaat
      541 gtaaccgtca gctcgttaat tacataaaag tttatagacg atggatgcca gcgaatgtcc
      601 ttggcgtagc cgatgctatt agagtatatt ttgagacagt aggttctata ggatgttaaa
      661 tttcaaaaaa aacgttagtg attattcgaa gtactatatt ttgagtatag tgttattatg
      721 gataggaatg ttctttgttc cttgggataa gactctattc ggtgtttcga tttatctgtt
      781 tgttatgcaa aagttattta tagtgtttgg tttgacggct atcttcatgg cctttgtgtc
      841 taaaaaaata aatctattta tttggggaat attatttatt ttcgcatttt ggattaatat
      901 gtttttgtta ttttccgtat taccaatttt ggggaattag tttaacaaaa aagaagaggg
      961 ggggttctcc ctcttctttt acgaataaat agataaggag gtgctttatg ctaacatacg
     1021 acgaatttaa gcaggcagtt gataacggtt atatcacagg cgacacagtc acgatcgtgc
     1081 gtaaaaacgg acagattttg gattatgtgt tgccgcatga ggaagtaagg aacggggagg
     1141 ttgtgacaga cgaaaaagtg gaagaggtga tgagagaatt agacaaataa aaaagacctc
     1201 gtccagaagt cggggaattg tcggggacaa cgtttgtaaa tgtttctatt ccaacataaa
     1261 acattttttg atataatagg aaggatcata tgcaaaggag ctgaaattgg acaagcacaa
     1321 aaggctcaaa acagttttat atcaatgtgc cagcttggtc gtactgcttt gtcttggagt
     1381 gatgagcatg ttttatcttg ctgttcatga tcaatttgac aagaaatcaa ggttagccga
     1441 gatagcaaaa tcaagagctg gtgtcatctc aattgatcat attgattgct atcatggcac
     1501 tcagagctac ctcagtcttt ttggaaaaaa caaggcaggc aataccatca tcgtcacaat
     1561 agaggagcaa tcagagcagc tcttgcttag tcgccctagc aatggcatta gtgctaagga
     1621 agcacaggaa attgcctacc atgccggagc aaggactatt gaagcagtga catttgggat
     1681 tgaaaaccac aagaggattt gggaggtggc tgctcaaaac ggctactatc tgattgattt
     1741 caaaaccgca aaagtgatca aaaaggaggt tttatgacca agctatcaag gcgcgtgtta
     1801 gcaatggaag aaagcgtcac cctagcagca ggtgctagag caaaggcact aaaggctcag
     1861 ggacgcgata ttttaagcct aactctggga gagccagatt ttataacacc gcagcatatc
     1921 caagaaaagg ccattgaggc catcaccact ggtaaggcaa gcttttacac tgttgcttcg
     1981 gggttgccag agctcaagga cgccattgct gattacatgg cacgatccta tggttatatt
     2041 cctaccagac aggagattgt agtggggaca ggcgccaaat acgttttgta tgcctttttc
     2101 atggctgttt taaatcctgg tgatcaggtg ttgattccga ctccttattg ggtttcttat
     2161 gctgatcaga ttaaaatggt agacggggta ccggtctttg tacagggctt ggaggaaaat
     2221 caatttaagg tcacagtaga gcagctagag gctgccagaa ctgatcaaac aaaggttgtt
     2281 ttgatcaatt ctccgtccaa tccaactggc atgatttaca gccgacagga gcttgaagcc
     2341 attggcaatt gggctgttca gcatgatatt ctgatcctgg cagatgatat ctatggtgca
     2401 ttggtctaca atggcaatca atttactcca atatcagcct tatcagaggc tattcgtaga
     2461 cagaccatta ctgtaaatgg cgttgccaag agctatgcga tgacaggctg gcgtttgggc
     2521 tttgcggtcg gagacactga tattatcgct gctatgggta agattatcgg gcaaaccacc
     2581 tctaatgtga caacagcgtc ccaatatgca gcgattgagg cctttggcgg tgaccaaacg
     2641 tcagttgagg agatgagaca ggcctttgaa gagcgcctca ataccattta tcccctgctc
     2701 aatcaagttc ctggctttga ggctattaag ccccaaggag ccttttattt ctttcccaat
     2761 gtcaaaaaag ctatggagat gaagggcttt accgatgtga cagcctttac tgatgcgatc
     2821 ctagaagagg taggactggc tgttgtcagc ggagctggct ttggtgctcc agaaaatatc
     2881 aggctaagct atgccactga tttggcaacc ctaaaagaag ctatcagacg actcaatcag
     2941 ttcatgacaa ctgacagcag ccatgacaac aaagagaatg aatagaaaag agacattatg
     3001 accaaaaaat acgtttccat tatcgatgtt aaagaccatg taggacaaga agtgacagtt
     3061 ggtgcttggg tcgccaacaa gtcaggcaaa gggaaaatag cctttttgca attgcgtgat
     3121 ggctcagcct ttttccaggc agttgccttt aagccaaacc tgatccaagc ctttggtgag
     3181 gaagcaggag cagctaagtt tgacacgatt aggcatctca gccaagaaac ctctgtctta
     3241 gtaaagggca ttgtcaaaga ggacgctaga tcaaaatttg gctatgagct agacattacg
     3301 gacctagagg ttattgggga ttccaaggat tatccaatta ctccaaagga gcatgggaca
     3361 gactttctca tggatcaccg tcacctttgg ctgcgctctc gcaggcaggc agcaatcatg
     3421 caaatccgta atgccatcat ctatgcttcc tatgagtttt ttgatcaaaa tggctttatc
     3481 aagtttgata gcccgatttt atcaggcaat gctgctgaga acacaacaga gctatttgag
     3541 acagattatt ttggcaatcc agcctttctc agccaatcag gtcagctata ccttgaagct
     3601 ggtatgatgg cgcttggtcg cgtctttgac tttggtccgg tatttcgtgc cgaaaaatca
     3661 aaaacgcgcc gccatctgac agagttttgg atgatggacg cagaataccc cttcttatcc
     3721 catgaggaat ccttagacct acaggaagcc tatgttaagg cgatgattca gggtgtgctt
     3781 gatcgtgctc cacaggcatt ggagcttcta gagcgtgaca cagagctgct gaaaagatac
     3841 attgcagagc ccttcaagcg tgtctcctac gacgatgcga tcagcctgct tcaggagcac
     3901 agcacagatg acgatgccga ctatgagcca attcagcatg gcgatgactt tggctcaccg
     3961 catgaaacct ggatttccaa ttattttggg gtcccaacct ttgtcatcaa ctacccagct
     4021 agctttaagg ccttttacat gaagccggtt cccggcaatg aagagcgcgt gctatgtgcg
     4081 gacctgctag caccagaggg ctacggtgag attatcggag gctcggttcg tgaggataac
     4141 tatgacaaat tgttggcgaa aatcaaggct gaaggcctaa atcctgagga ttatgacttt
     4201 taccttgacc ttcgcaaata tggctcagtg ccgcatgctg gttttggact tggactagag
     4261 cgcatggtga cctttgttgc aggtaccaag cacattcgtg aggctattcc atttccacgc
     4321 atgcttcatc gcttaaaacc ataatgaacc ctatcagcgt ccgccattgg gcgctttttt
     4381 gctgcgctga gcagtactta gagctcaagc ctcccagtta gacttggcag agctgtggct
     4441 ctttgcttga gctattgtag gcaaaggtat cactggatct gaaaacaaca aaatcagaca
     4501 agtgatatca aaattaaaaa aaaaaaaaac gaaacctagg aggatcggtg agcttattag
     4561 tttggcacta atcatcatta tgctataatt gtcttcacaa ataatttaga aatagctcat
     4621 atttctatca ttaaaggaga gagatgatga atcgtaaaaa gcataccaaa ctcattcgtc
     4681 actacagtat ctgctcagca gtggctgtcc tagcagcagt tagcttggga acaggtcagg
     4741 acgtacaggc ttcggaaccc aatccatatc cagatgtgag gcgtttcctt gatgagaagt
     4801 acgatggaga tgtggataaa ttatctaaac aacttcaagg ttattttggt agtttaagag
     4861 agtatataga gtttgaactt aaaaatggca aacaaggtcc tgctggccct caaggcccaa
     4921 agggtgataa aggagactcc ggagagccag gtcctcaagg tccagtgggc cccgctggtc
     4981 caaagggtga tcgtggttta gacggacgac gtggcccagc aggtcagcaa ggggaagtcg
     5041 gcccagttgg tcctcagggt cctcaaggcg agcaagggcc aaaaggcgac cgtggcgaac
     5101 aaggaccaaa gggtgaacgc ggtgagcaag gaccaaaggg tgaacgcggt gagcaagggc
     5161 caaaaggcga ccgtggcgaa caaggaccaa agggtgaacg cggtgagcaa ggaccaaagg
     5221 gtgaacgcgg tgagcaaggg ccaaaaggcg
//
LOCUS       DARYLJ010000080         4804 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYLJ010000080 DARYLJ010000000
VERSION     DARYLJ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4804
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            15..743
                     /locus_tag="TU746_001868"
     CDS             15..743
                     /locus_tag="TU746_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0892169.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            755..1930
                     /locus_tag="TU746_001869"
     CDS             755..1930
                     /locus_tag="TU746_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL0892170.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            1940..2935
                     /gene="lacD"
                     /locus_tag="TU746_001870"
     CDS             1940..2935
                     /gene="lacD"
                     /locus_tag="TU746_001870"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL0892171.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(2977..3696)
                     /locus_tag="TU746_001871"
     CDS             complement(2977..3696)
                     /locus_tag="TU746_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0892172.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            3836..>4804
                     /locus_tag="TU746_001872"
     CDS             3836..>4804
                     /locus_tag="TU746_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0892173.1"
                     /translation="MKQFCIKEQFYLDGKPFNILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDDVFVTGNFGSNASKQF
                     ASMQDFFQAHQKQWPLMCMEFWLGWFNRWNEPIIRRDSKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQ"
BASE COUNT         1352 a          869 c         1181 g         1402 t
ORIGIN      
        1 ttagaggtgt tagtatgata aaggaacagc cactctactt acaaattgtt gatgtattag
       61 aggtcaaaat tagaaatacc atgtcagcta atgataaatt gttatcagaa cgagagctaa
      121 gtgacttatt tggtgttagt cggataacca ttagattggc acttaaggag ctagagctgc
      181 gtgggcttat ttacaaacag cagggcaagg ggacctatgt atcaggcata aaggagcctg
      241 ctacagacct gtcctcagcc tatagcttta ccgaagagat gaaaaagcaa ggtcgtaagc
      301 ctcaaacagt cattctttca tttgaaaaaa tcaagaccac agcttacttg tctggtatgt
      361 tagatttaga tgttgatact gatgtttttg agctagagcg tctaaggatt gcagatggaa
      421 agccattaat gtttgagcgc acttatatac ctgaaagggg atttgaggcg ataacgattg
      481 atttattgga aaaaaagccc ttatatgatg tgtttgctga ggattttcag gaagctatcc
      541 gattggctga tgaggagttt tacgctagta tcgctctaga ttatgaagca aagctattag
      601 ggatcaaaaa gggggatcct gtgctgcata ttatgcgtaa gacctataat gagaaaaata
      661 ggctaatcga atttaccttt agtattgcta gagcagacca gtttaggtac cgtatccagc
      721 accaccctaa caagaagata taggaggtaa ggaaatgttt acaaaaacac aagcagaact
      781 agagctactt ggcgcagcta tcaccactag agaaatcaag cagcagccag agctatggtc
      841 agaggtcttt gagtcttttc tgaagcaaaa aaaagacctc ttagcctttt ttgacaggat
      901 tattgaaagc gctaacagaa acaaggtaaa aattattttt acaggagctg gaacttctga
      961 atacattggc aataccattt gtcattattt ggagatgact ggtgacaggg aaaattattt
     1021 atattacagc attgcttcca cagaccttgt tgcagctcca agccagtatc tctttgaaga
     1081 ggatacagtc gtgcttgttt cctttgcaag aagtggcaat agtcctgaaa gtgtcgctgc
     1141 tgttagtctt gttaatcagc tggtgtcaaa tccttatcat ttggtgataa cctgtgccaa
     1201 agagggggcc ttagctcaaa atgctaagaa ggacaaaagg agctatttat tcttgctgcc
     1261 tgaggcctca aatgacgctg gctttgctat gacgggaagc tttagctgca tgatgctagc
     1321 ggccttgttg atttttgatc aagcgcattc ccttgaggag aaaaaatgct atttagatca
     1381 gattgtaggt atggtggcag ctattattca gcaggaggct gatttacaaa agctggttag
     1441 cttagagttt caacgcttgg tttacctggg atcaggagcc ttagcggggc ttacgcaaga
     1501 ggctcaattg aagattttag aattaacagc tggcaaaatt gcaacagtct atgactcctc
     1561 aatgggcttt aggcatggtc caaagtcatt tattgatgat cagacattgg ttattggttt
     1621 tgttagcaat gatccttata cgagaaggta tgaccttgat gttttagaag agataagaga
     1681 ggatgctatt gctgttgata cggttgcatt acagcagcaa ggaggtgagg gctttagtgg
     1741 gcattgcttt ggcttagact cgtcaatgct attgccagat gcttatttgg cctttccgct
     1801 tgtttttatc gcccaaacgc ttgctttgct gtcgtctatt aaggttaata atttaccaga
     1861 tactccttcg gccacaggaa cggttaacag ggttgtccaa ggtgttaaga tttatcacta
     1921 ttttaagtag gagaacaaga tgtaccattt atcaaaagct aagtatcgtc ttcttgaaaa
     1981 ggtcagtcgt aagggcatca tttcggcctt ggcctttgat caacgcgggg ttttaaagcg
     2041 catgatggca gcccaccaag acacagagcc aactccttgg caaatcgaag ccctaaaggc
     2101 tctggtatca gaggagctaa ccccctatgc ctcctctatc ctgctagacc ctgaatatgg
     2161 cctgccagcc accaaggtgc gtgatgagaa gtctggctta ttattagcct atgaacaaac
     2221 cggctatgac acaaccacca ctagccgcct gccagattgt ctggtggact ggtcagtcaa
     2281 gcgcctcaag gaggccggag ctgacgcagt gaagttcttg ctgtactatg atgttgatgg
     2341 tgatgagcgt attaaccaac aaaagcaggc ctatatcgag cgtatcggct cagaatgtca
     2401 ggcagaggag ataccatttt tccttgagct attgacctat gatgaggcga taacagacaa
     2461 tcagagtgta gcttttgcca agctaaaggc acacaaggtt aatgaggcca tgaaggtctt
     2521 ttcaactgag cgctttgggg ttgatgtcct aaaggtagag gttcctgtca atatggccta
     2581 tgttgagggc tttgcagagg gtgaggttgt ttacagcaaa gaggaggcta tgcaggcctt
     2641 tcgtgaccaa gaggcagcta gtcacttgcc ctatatttat ttgagtgcgg gtgtatcagc
     2701 tagtctgttt caagagacct tggtttttgc ggcagaggca ggagctaggt tcaatggtgt
     2761 gctgtgtggt agggccactt ggtcaggagc agtagcggtg tacatgtcag agggcgagga
     2821 ggcagcgcgt caatggcttc gcacagaggg ttttgaaaat attgatcgtc tcaatcaggt
     2881 gcttgagaaa acagccagcc cttggacaac aaagcttact cttgatgaag cctagtaaag
     2941 gcatgataaa agcaatacta ggacattgct tctgtattat tggtaatcac tggaggacaa
     3001 ggcgtacttg aaaaattgcc aatgcttgta ggactcggtg tactctagaa tacggccatt
     3061 atctgtcgac cgagtgagct tggtttgaag gacacaagga gtgttgtcta tcatgtttaa
     3121 aaatgtagcg acatctttag gcatgtgatc cgtcagctgt gtttgctggg tgaagctttg
     3181 tgatcgcatt tgaatgtgaa aatccaaaaa gaagcgctta taaagcgact ggtaatcagc
     3241 taaatcacgc tcagggcaca gcaggtaatc atgaggaata taagatagct ggtataaata
     3301 gggctgctga ttaatcgttc gtgtacggga gatggtgtag taaaattccg ttttatgaag
     3361 tttcaagaga tttagatagt agggatcatt tcccttaact acactaagga cagtcacctc
     3421 ctctttttga tccttaaagg tacctagata ggaaaattgg actagctgtt cttttctggt
     3481 acgggtaatg aaggttccaa gtccctgcct tcttctgata aagccttctt tttctagttc
     3541 tttaagggct cgaatgatgg ttatggagct aacatgaaag cgtttaatca gctcggcttc
     3601 ggtataaaat ttgtccccgg tatggtagtg gccattcaga atttggtttt gcaattcttc
     3661 tttgattagt cggtactttg ggtatttgat ggtcatagtt actcactcaa taattgttta
     3721 gtacgattat agcaaaaata gtaagctgat gtcatatctt accagttatt gctcagatag
     3781 cttgtcaatc agtcattgat caaaggctga tggttaatga ataaaaggag ataatatgaa
     3841 gcaattttgc ataaaggagc agttttacct tgatggcaag ccgtttaata tattatcagg
     3901 tgccattcat tactttagaa tagctcctga tagctggtct agggtgcttt atcagctgaa
     3961 ggccttaggc tttaatacag tagaaaccta tattccttgg aatatgcatg agccaaggaa
     4021 gggacagttt acctttgagg ggattgcaga tgttgaggca tttttggatt tggcacagga
     4081 atgtggccta tatgctattg tcagaccctc tccttatatc tgtgctgaat gggagtttgg
     4141 tggtttaccg gcttggctat taactgaaaa ttgtaggctc agatcaagcg atgaggtctt
     4201 tcttaagcat gtatcagatt attatgatgt gttactacca aagctggtga agcgtcagtt
     4261 agataatggc ggcaatattc tgatgtttca gcttgaaaat gagtatggtt cttatggtga
     4321 agaaaaggct tatttaagaa aattaaaaga gcttatgctt gctaaaggca ttagtgcccc
     4381 tctctttacc tcagatgggc cttggccagc cacgctagca tcagggagtc tgattgacga
     4441 tgatgttttt gtgacaggca actttgggtc aaacgcttca aagcaatttg ccagtatgca
     4501 ggattttttc caagcacatc aaaagcaatg gcctctgatg tgtatggaat tctggttggg
     4561 ctggtttaat cgctggaatg agccaatcat tcgaagggac tccaaggaag ctgttgatgc
     4621 aatcatggaa gctatagagc taggcagcat taacctttat atgttttgtg gtggcactaa
     4681 ttttggcttt atgaatggct cgtcagctcg tctgcaaaag gatttaccac agataacctc
     4741 ctatgattac gacgcattac tagatgaggc agggaacccg acaaagaaat ataccctgct
     4801 gcaa
//
LOCUS       DARYLJ010000081         4565 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYLJ010000081 DARYLJ010000000
VERSION     DARYLJ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4565
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..357
                     /locus_tag="TU746_001873"
     CDS             <1..357
                     /locus_tag="TU746_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0892174.1"
                     /translation="NSKIKTEPQLLLRIMENLITNAVNYSVKGTSININVEEINGMLK
                     ISVINDVSPNLNVNWNMVTSKFYRGDLSRRISNNGSGLGLTIVNDIVKHLGGNFEIGE
                     ENKRVCAKVILPYRLN"
     gene            635..1018
                     /locus_tag="TU746_001874"
     CDS             635..1018
                     /locus_tag="TU746_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL0892175.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
     gene            1126..3294
                     /locus_tag="TU746_001875"
     CDS             1126..3294
                     /locus_tag="TU746_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892176.1"
                     /translation="MKKTVGILAILLIIVIGIGKFFYSDGMFLNIFIKEFNTTVNIVT
                     KPEIADKTIIELQKIANKNDLSFIKEEYIPKNSRFDKQKMKIYIHLNDSEWFKKSFRN
                     ISIADSKDKLNDFENVKSMSLLTSKDISLIPFENVNKEKVNGDYHVRGTEENINKFIE
                     EINQNEKLKTEVVVNPDFIVSSEFTQKQAYLYMLTIFIIFVATVFCLIIYNGMLSKEL
                     SISILLGCDELTLAIAKVLNILAIPAIVGLVLTIGIIEYLVAPSDILGFMISMKTILI
                     LVAFIIGGLISIEFILIYLKLKGINVIALLKGYRRSYHRSSFFIKTGSIVMVLYLAIV
                     SILGLTDYLSMRQYIPTWESSKYYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLD
                     DSGAILFNAPNVRKEGMNDDEEYLNQQPFQGNYAYVNKNYLHIANLLDKDTNKIEQYK
                     IHENEWIVFVPEDVKITELDKEKIHEDHIFQNIKKQGTIIETYVRLKDNQSVFSFDSG
                     KRIDEANLKNYVLVAVNGKELLPDHGIKLSSLVNGQLHPYVKEPSRAYESLKDIIEET
                     ESEPFILYISSVYDDIVSRIDEYKMEASIYVIGLVLSIVILATLLKIDKETYFYNHGQ
                     RIDVSRLLGYGFFDIHHKKIIGNIVGYIISIIILFMVIMVTGVISDVGLFIPRDGWSM
                     SKLLISLIIGICGSFICFGIEILQLKKSERSIVLRLKEGC"
     gene            3295..3969
                     /locus_tag="TU746_001876"
     CDS             3295..3969
                     /locus_tag="TU746_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0892177.1"
                     /translation="MQNEKELQITLRNVSKKYGEHSILENISLDIYKGDFVCIFGKSG
                     GGKTTLLNIIGTLENYDSGSVTCFSNRDPIKAPKVGELLRREKIAYLFQNFALVEKMT
                     VEENMMLAAKYNQEKNKKNLIEAALNKMGISDKLKSKVYELSGGEQQRVALARNMIKP
                     FEIMLADEPTGSLDYENKKIVIDTLIRLNDEGKTIVVVSHDKDFEKVAHKNYIIEKSA
                     IREVLR"
     gene            3966..4562
                     /locus_tag="TU746_001877"
     CDS             3966..4562
                     /locus_tag="TU746_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0892178.1"
                     /translation="MKRKIALLVPVIVLCICGLFFYMNRNSDDIDVAFTVKNETKEKI
                     DTVGIAMGNKCILNRTNGEKFYFPKDLIKEKQGKAIVFVVSKDGIIAKSGEIDLKENK
                     EVSIREIKEGEISLDIAAQKTDIKISIPRLDDWKVSTDEKFIKGSYEANTDSQYTLYL
                     LGKGGNLGISGTEMKGVRVIVSWEKPKDKIDSWLVFND"
BASE COUNT         1763 a          460 c          901 g         1441 t
ORIGIN      
        1 aacagtaaga ttaaaacgga accacaactt ttacttagaa taatggagaa tctaattaca
       61 aatgcagtta attattctgt gaaaggaaca agcatcaata taaatgttga ggaaataaat
      121 ggaatgttaa aaataagtgt tataaacgat gtttctccaa atttaaatgt gaattggaat
      181 atggttactt caaagtttta taggggagat ttatcaagac gaataagcaa taatggatcg
      241 ggacttggac ttacaattgt aaatgacatt gtaaaacact tgggtggaaa ttttgaaatt
      301 ggagaggaga ataaaagagt ttgtgctaaa gtaatacttc catatagatt aaattaaatc
      361 gcaaagaaaa cgcaagaatt attcaaagat accgttaagt ataaagcaaa gagctattct
      421 ataatgtgag taaggatagc tcttttatat ttgaaaggaa ttattaattt gaataagcat
      481 ctgtgattat aaatatataa aatggaggtg gagttttatg aattacaata atcctcatag
      541 gtataggaac ggagattgag tagagttttg ggaaacttta ttcggaagaa aaattttaca
      601 aaaaatttaa gtatttgaga gaggagaatt tatcatgaaa aaagcattgt cattagtatt
      661 attaacaggt ttgatgttag catcatctgt accagcattt gcagcagaag aaacaaactt
      721 gccatatgtt gaaggtcttg gttatgaggt ggaagtattt gaagaagatt atactcagcc
      781 aaagttgttc agttatgata gcggatggaa aagtttttta ggtggaaaat ggagacatgg
      841 tgtaggtagt cgatatgttt ggtctaaata cgatcacaat aataaaacac ataaaactac
      901 agtacaaggt gctggtggtc aattctctta ttcgggttgg acaagcgctg gaagtagagc
      961 agaagcttct tgggaaaaag ctttaagtgg taatagggct tgggctgatg ttaaataaca
     1021 ataaataaaa aatagttgaa cgagtttgag cggtgccacg ttgttatttt agcattgtgg
     1081 cattactcat actcgctatt tttataaagt tggagatgat acagaatgaa aaaaacagtg
     1141 ggtatattgg caattttact aattatagtg attggtatag gaaagttttt ctattcagac
     1201 ggcatgtttt taaatatatt cataaaagag tttaatacta ctgtaaacat tgtaacaaag
     1261 ccagaaatag ctgataaaac aataattgaa ttgcagaaaa tagctaataa aaatgattta
     1321 agcttcataa aggaagaata tattcctaag aatagtagat ttgataaaca aaaaatgaag
     1381 atttacattc atctaaatga ttctgaatgg ttcaagaaat cttttagaaa tatatctatt
     1441 gctgatagca aagacaaatt gaatgatttt gagaatgtaa aatcaatgag tttgctgaca
     1501 tcaaaagata taagcttaat tccttttgaa aacgtcaaca aggaaaaagt taatggggat
     1561 tatcatgtaa gagggacgga agaaaatatt aataagttta ttgaagaaat aaatcaaaat
     1621 gaaaaattaa aaacagaagt cgtggttaat ccggatttta ttgtttctag tgaattcaca
     1681 cagaaacaag catatctata tatgcttacg atttttatta tatttgtagc tactgtcttt
     1741 tgtctaatta tttataatgg gatgctttca aaggaattat cgatatcaat tttactagga
     1801 tgcgacgaat taactttagc tattgctaag gttttaaata ttcttgcaat accagcaata
     1861 gtgggacttg tactgacgat tggaattata gaatatttag ttgctcctag tgatatttta
     1921 ggatttatga tatcaatgaa aacaatactt attttagttg cttttataat aggaggtcta
     1981 atatcaatag agtttatatt gatttatctc aaattaaaag gaattaatgt tattgcctta
     2041 ttgaaaggtt atagaagaag ttatcataga agttcttttt ttataaaaac agggtcgatt
     2101 gttatggttc tttatctagc aattgtaagt attttaggac tcactgatta cttgagtatg
     2161 agacaataca ttccaacttg ggaaagctca aagtattatg caaatatggc ttgtgcatgg
     2221 tcttggagtt atgaaaaaga tgatgataag ttccatgaaa ttgttattcc aaagctgaat
     2281 aacttatgga atagtttgga cgatagtgga gcaatattat ttaatgcccc aaacgttaga
     2341 aaagagggaa tgaatgatga tgaggagtat ctaaatcaac aaccttttca aggtaattat
     2401 gcctatgtaa ataaaaatta tttacatatt gctaatctct tagataaaga tacgaataaa
     2461 atagaacaat ataaaataca tgaaaatgag tggattgttt ttgttccaga agatgttaaa
     2521 attactgaac ttgacaaaga aaaaattcac gaagatcata tttttcaaaa tataaaaaaa
     2581 caaggtacaa ttatagaaac atatgtaagg ctgaaagata atcaaagtgt attttctttt
     2641 gatagtggca aaagaattga tgaagcaaac ttgaaaaatt atgttttggt agcagtaaat
     2701 gggaaagaat tactcccaga tcacggaatc aaactatcat ctttagtaaa tgggcagcta
     2761 catccatatg ttaaagagcc tagtagggca tacgagagtt tgaaggacat aattgaagaa
     2821 acagaatctg agccgtttat actctatatc agctcagttt acgatgatat agtttcaaga
     2881 atagacgaat ataagatgga ggcaagtata tatgttattg gtctcgtctt atctattgtt
     2941 attttagcaa cgttattaaa aatagataaa gaaacatatt tttataatca tggacaacga
     3001 atagatgttt ctaggttgtt gggatatgga ttttttgata tacatcataa gaaaattatt
     3061 ggaaatatcg ttggttatat cataagtatt attattttat ttatggttat tatggtaaca
     3121 ggagtaataa gcgatgttgg actgtttata ccaagagatg gttggagtat gtctaaactt
     3181 ttgattagtt taataatagg tatttgtgga agctttatat gttttggcat agaaatttta
     3241 caactaaaga aaagtgaaag aagcattgta cttaggttaa aggagggttg ttaaatgcaa
     3301 aatgaaaagg aattgcaaat aaccttaaga aatgtctcta agaaatatgg agaacacagt
     3361 attttggaaa atattagttt ggatatttat aaaggagatt ttgtttgtat ctttgggaaa
     3421 agtggaggag gaaaaacaac acttttaaat ataattggga cattagaaaa ttatgatagt
     3481 ggtagtgtaa cctgtttttc aaatcgagat cctataaaag ctcctaaagt aggagagcta
     3541 ttacgcagag aaaaaattgc ttatttattt caaaattttg ctttggtgga aaaaatgacg
     3601 gttgaggaaa atatgatgct tgctgcaaaa tacaatcaag aaaaaaataa gaaaaatctt
     3661 atagaagctg ccttgaataa aatgggcatt tcagacaaat taaaatcgaa ggtttatgaa
     3721 ctttcaggtg gagaacagca aagggtagct cttgcaagaa atatgataaa accgtttgaa
     3781 attatgttgg cggatgaacc gacaggttct cttgattatg agaataaaaa aattgtaatc
     3841 gatacactta ttagattaaa tgatgaaggt aagacaatcg tagttgtaag tcatgataag
     3901 gattttgaaa aagtagcaca taagaattat attattgaaa agtcagctat aagggaggtg
     3961 ttgagatgaa aaggaagatt gctttattag taccggttat agtactgtgt atttgtggtt
     4021 tattctttta catgaacaga aatagtgatg atattgatgt tgcatttaca gtaaaaaatg
     4081 aaacaaaaga aaaaatagat acagtgggta ttgcgatggg aaataaatgt attttgaata
     4141 gaacaaatgg agaaaaattt tattttccaa aagacctaat caaagaaaaa caaggcaaag
     4201 ctattgtttt tgtagtatct aaagatggaa tcatagcaaa gtcaggggaa atagatttaa
     4261 aagaaaataa agaagtaagt ataagggaaa taaaagaagg agaaatatcc ttggatatag
     4321 ctgctcaaaa aacagatata aaaattagta ttcctaggtt agatgattgg aaagttagta
     4381 cagatgaaaa atttatcaag ggctcttatg aagcaaatac tgattcgcaa tatacattat
     4441 atttattagg aaaaggcgga aatttaggca tttccggtac ggagatgaaa ggagtacgtg
     4501 ttattgtaag ttgggaaaaa ccaaaagata aaatagatag ttggcttgta tttaatgatt
     4561 aaaaa
//
LOCUS       DARYLJ010000082         4486 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYLJ010000082 DARYLJ010000000
VERSION     DARYLJ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4486
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            295..2097
                     /locus_tag="TU746_001878"
     CDS             295..2097
                     /locus_tag="TU746_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL0892179.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            2075..2674
                     /locus_tag="TU746_001879"
     CDS             2075..2674
                     /locus_tag="TU746_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0892180.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2782..3708
                     /locus_tag="TU746_001880"
     CDS             2782..3708
                     /locus_tag="TU746_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL0892181.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3701..4072
                     /locus_tag="TU746_001881"
                     /pseudo
     CDS             3701..4072
                     /locus_tag="TU746_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(4106..>4486)
                     /locus_tag="TU746_001882"
     CDS             complement(4106..>4486)
                     /locus_tag="TU746_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL0892182.1"
                     /translation="TLSRSPDLKQVQTMLEKAFPADSYNGTILHSDQGWQYQHQSYHH
                     FLESKGIRPSMSRKGNSPDNGMMESFFGILKSEMFYGLETTYQSLNELEQAITDYIFY
                     YNNKRIKAKLKGLSPVQYRTKSFH"
BASE COUNT         1372 a          831 c          879 g         1404 t
ORIGIN      
        1 gcctgtgccc taaccctctc acctagacgc aaaaagaatc aaaacaaccg ttaataggaa
       61 atcatgaaag ccttctatga cagtcattgt tcataggagg ttttttacac caaatagacc
      121 ttctattggc ttttcatttg attcttaatg gatttttact gctaatttct gactcaccat
      181 cgttgcattc gtctcattat ttacaaattt atttggctaa tattgaaaat atgttatgat
      241 taatgtatta ttttggtatt atttttaaaa aatattattt tagaatggta aaaaatggag
      301 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
      361 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      421 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      481 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      541 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      601 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      661 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      721 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      781 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      841 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      901 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      961 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
     1021 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
     1081 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
     1141 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
     1201 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
     1261 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1321 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1381 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1441 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1501 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1561 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1621 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1681 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1741 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1801 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1861 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1921 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1981 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     2041 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     2101 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     2161 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     2221 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     2281 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2341 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2401 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2461 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2521 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2581 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2641 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2701 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2761 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2821 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2881 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2941 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     3001 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     3061 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     3121 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     3181 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     3241 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3301 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3361 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3421 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3481 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3541 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3601 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3661 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3721 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3781 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3841 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3901 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3961 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     4021 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggacttc ctgtgtactg
     4081 acccccaaaa gttggacacg acatattagt gaaaggattt agttctgtat tgcacagggc
     4141 taagtccttt tagctttgct ttaatgcgtt tgttgttgta gtaaaaaatg taatctgtaa
     4201 tagcttgttc aagctcatta agggattgat aagttgtctc aaggccgtaa aacatctcag
     4261 atttgagaat accaaagaag gattccatca tcccattatc ggggctgtta cccttgcgag
     4321 acattgatgg acgaatgccc tttgattcta aaaaatgatg ataggactga tgttgatatt
     4381 gccacccttg atcgctgtgg agaatcgttc cattgtacga atccgctgga aaagccttct
     4441 caagcatggt ttgaacctgt tttaagtctg gagacctaga tagtgt
//
LOCUS       DARYLJ010000083         4192 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYLJ010000083 DARYLJ010000000
VERSION     DARYLJ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4192
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(44..754)
                     /locus_tag="TU746_001883"
     CDS             complement(44..754)
                     /locus_tag="TU746_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL0892183.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
     gene            complement(1201..2559)
                     /locus_tag="TU746_001884"
     CDS             complement(1201..2559)
                     /locus_tag="TU746_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL0892184.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSRYFLLYFPI
                     LGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHK
                     VPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIA
                     VHLINIVSLETASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTF
                     LCHIEVIGFSSVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWK
                     ML"
     gene            complement(2967..3197)
                     /locus_tag="TU746_001885"
     CDS             complement(2967..3197)
                     /locus_tag="TU746_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892185.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(3291..3704)
                     /locus_tag="TU746_001886"
     CDS             complement(3291..3704)
                     /locus_tag="TU746_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892186.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLISGIVSWIYHLYLRKVE"
     gene            complement(3739..3936)
                     /locus_tag="TU746_001887"
     CDS             complement(3739..3936)
                     /locus_tag="TU746_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0892187.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
BASE COUNT         1315 a          808 c          562 g         1507 t
ORIGIN      
        1 gctagaactc aagccttgga gtgctaagtc atttttctat tctttagtag cccattcgtt
       61 gtgcccatgc cttatcaata gcaagggttt cagtgtctgt atagctcttg cgataaggat
      121 tccagacaga ggtcaaagga gccgcagcaa gcgcttcttg cgcctgatta tttactatat
      181 cataggccgt tagaccgtag gtctcaatga tgttgtttaa tttccagtta tagctagtat
      241 ctgtagcata caagcctgtt aaagctgctg tagcgtcctg ataagacaag gtatttgact
      301 ttctagcacc tgcataaata tctgagctaa gcaaattagt gtaatcatat aaggaatcag
      361 ccactgtcgg ataagctcta aaggtttgat cgatgtagta agtatttcca gccccatcgt
      421 cttcccatgt tgtcatcgtc actgatgacc cattataagc ccctttaatg ccaaaaaaat
      481 tataataagg tgcttgactt aaagctgatt taccgttagc tgactctaaa atagcttgag
      541 caatcataac cgaagcatac aagtctcttt cttgagcaac aacactagca gttgctccaa
      601 tctcttcaat aaaggcttgc gttgacgacg ttgacacagt ctctgctgag acatctgatg
      661 tattttctga ctgtctaatt gaactataaa cacctaagca ggctactaga acaaaaagac
      721 tgataagtgt gagcttacct ttcttttttg ccatttatca ttccctcttt ttttgataaa
      781 tagattatag cacagaatgc tcataaaaag acttatccac aaacaattta atcatattga
      841 taacttttgt ctttaaatcg aaatatttta atgtaaagaa ggcttaccaa gtccataaag
      901 cgaaggcttt tcataatctt ttacgcctta tttgctatat cgccttgtaa tagcttcaat
      961 acctttgaaa ggttattaca cctactattg ttctttatgc ctgtctgtta agtattttcc
     1021 atttaactgc ctttattttt taggtaaaga aaaaacagta aaccattaat ttactgtttc
     1081 ttaattgata tttaatattt tcttataact attgatgtta aataaatgaa aatatatcat
     1141 tcttgtttac taccaacttc taactagtat agtacgagga tataattaaa tcttcgtctt
     1201 ttacaacatt ttccaatata acgctagtgg taacaacaat aataatccaa tagctgatac
     1261 aatcgaacaa tatattgtca ttcttgcttt tgataaattt tcattttgta aaaccaccat
     1321 caagggtggt gcctgaaatg ggaaaaatac acttgaaaaa cctataactt caatatgaca
     1381 taaaaatgtt tttgaaacat tactaacgcc tgaaatatta tcaatcaaag gtgtaactac
     1441 tgccggaaca cccggtaaag ttactataaa tcctaatata atacacaata caacgaaaaa
     1501 agttaaaaca ttaaatgcac ttgctgtttc caaagaaaca atattgatta aatgcacagc
     1561 aatgacattt gcaagtcctg aagattttgc tatattccct aaacttatga ttccagctac
     1621 ataaaaaaat ggctcaaaat ttatttttct taaaggttgc ttttccataa aatttgaatt
     1681 tggtaacatt acaatcaagg cagttgccat tcctgtccaa ccggttggta ctttatgaat
     1741 atgttctgtc atccagaaag acagagttat aaataacaaa actattaaca atttctgctc
     1801 ttttgttatg tcaatggctt ttttggacac gcaaatcgaa tctttacatc ttctataaaa
     1861 taaccgcatt gtaaaatata aaatcaatat ttttccaact cctaaaatag ggaagtacaa
     1921 gagaaagtat ctgctatagg atatatttat ggagtaaaga cttaaaattg ctccagtaaa
     1981 aacattattt ggaacattgg aaggtaatac ataaaatgca ggtatatagg ttgctaaaac
     2041 ccctgacata acaattcctt cccattcctt acttcctttt tcataaccta attctaaaga
     2101 tagggcattt agaataggta aaagcaaaac tactctaccc attgctgatg gcatcaaaaa
     2161 aattagtacc actcctagca aaatcgtccc aaataacact ttagaatatt tccccatgca
     2221 caccggaata aaaaatctcg caagtaatct atcaagttca gtatgcttta ctgccgcccc
     2281 tataataaca cctgaaataa caagccatgc tgcacctgaa gttatccctg ataagatgac
     2341 ttgcttctca gctatattcc ctatcataca agctgtcata aataaaatgc ttgtatacca
     2401 tgcaggaatt atattgcttg ccaaaaggaa gatagatata agaatcaaaa taaaaacttt
     2461 ctctatattt gaaataaatg gtagtacaga tacaaacaac ggtaacattg taaatatcca
     2521 ctttatatga ttattcctaa ttccagattt taaaatcatc ctccattttt gacctccaac
     2581 tctaatttat ttcatagtat tataccatat ttattttcat tttataggtc tacctcttgc
     2641 ttctttgtct gtgttaatcg cttttcttgt ttttataact gctctataca agtcttaact
     2701 ttttctgcct gtttaatttt ttctcgtatc tctaatattt tattgtgtaa gctctttttt
     2761 tctttcttca tattggcgac ttccgatttt catttgctaa tgactaaggt cttgctttcg
     2821 cccaaatgct cttttagata tttcttggca ctctcaaata aaataatctc tgctgtatca
     2881 acgttagctg atatgccctc tgcaagagcc ttcggagaac gcacgcacct gttgaggtgt
     2941 atatgtacac tcttgtaaac aagggactat tcctctgtgt ccgttgcttc ctcttgcact
     3001 tctatgtttt cttctgtttg ttctcttttc tctatgattt ttaggatttt ttgattgact
     3061 gctccctttt cataaaggcg tctatctctc ttttttctct cttcctgttt cgactgaatg
     3121 atgggctttt ttcttttgtt ttgtaactgc ttgatttctc catctgtcat taaaattttt
     3181 tcatctatgt ttttcatttt ctattttcct ctctttctgt tttgagcaac aaaaaaacag
     3241 taaaccattt ttttgattta ctgttttcta ataaatatta tcttagttat ctattctact
     3301 tttcgtaaat ataaatgata aatccatgat acgataccac ttatcaaaac aactccaatt
     3361 atagaaaacc cagaaacttt gtttaaatag cccataaaaa ctagaagaaa aaaaactatt
     3421 cccagtaaag ttgtttgaat cacatatcct accatattag ccttagctgt tattaaggac
     3481 tctctttcat cggtttcatt tatccaatct tgttttttac ctgaaattga aaatacccat
     3541 attccactaa cacacagaag aatagcaaca acgagaaagc ctacccatgc aatatccatt
     3601 cttggaaata cctgtaaaat atctttttta aaaaataata tgcaagcaat caaggcaaaa
     3661 agtattccag tagcaataac tataatagct aactttcttg ccataaccat ctcttttttt
     3721 atatttcttt tcattttttt attcctcctc gtatataaag atatcttcaa tgcttaaact
     3781 aaaatactta gcaattttaa aagctaaaat aatggaagga ttataccttc cgttttctaa
     3841 agaaccaatt gtctgccttg atacttcaag aatagatgct aactcttcct gtgttattcc
     3901 attttctttt ctgatttcct caagtctatt tttcacattt aatgacctcc tgcaacaatg
     3961 acaagctaac tttacatata gtataatgtt ttttagagaa aatggcaagt atactttcca
     4021 taaaatcgtt tccttatagg tctagccctt acttttttac atgtacgact cctctatatc
     4081 tgcattttcc tcttatactt ctgtctgttg atgagcactt gcttctcttt gtgatgatat
     4141 ctttactatg cttttcattt ttgggatttt tatcttaatt ttgagtagtc at
//
LOCUS       DARYLJ010000084         4088 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYLJ010000084 DARYLJ010000000
VERSION     DARYLJ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4088
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            229..486
                     /locus_tag="TU746_001888"
     CDS             229..486
                     /locus_tag="TU746_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0892188.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            523..1254
                     /locus_tag="TU746_001889"
     CDS             523..1254
                     /locus_tag="TU746_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892189.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            1259..2887
                     /locus_tag="TU746_001890"
     CDS             1259..2887
                     /locus_tag="TU746_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0892190.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(3398..>4088)
                     /locus_tag="TU746_001891"
     CDS             complement(3398..>4088)
                     /locus_tag="TU746_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892191.1"
                     /translation="DDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDVK
                     IKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNNV
                     TKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSLF
                     HLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNKQ
                     VSDDAFHIWVK"
BASE COUNT         1109 a          756 c          913 g         1310 t
ORIGIN      
        1 gattatcgtc tgattttgtt acctatggct aaaaataaga agcacaactg actgcccgta
       61 ttgccctaaa aaaggaacaa aagtaagcgc catcatcgtt ggtatatctg cttttgtgaa
      121 aagagacaaa tatggcgata ggatattgac aaaaagccta ataaagatta tgattgaagt
      181 gttaactagt tgtattagcg taaacgtaca aaattagagg gaggccctat ggaaaaggaa
      241 cagcagcgct tatacgatgt catcaaacag gcctacgatt acccagaaaa tcgtgctaat
      301 agccatttag ccagattatt gctgtcagct tctaaccaat taatcaaaaa cagtaatccg
      361 ctgacgattg cagagcagct aaatcaagcg cttgatgatt acttacaggc caatgatttg
      421 ttgttgccta agtccttgtg tggctttaag cagtcgcttg acgcttattt attagaaaaa
      481 ggctgaccag cacgagcgtc tggtttagga taggagagag ttatgataga atttagacat
      541 gtttcaaagc tatacggtga caaggaggcc ttgagtgatg taagcctcac gattaaggac
      601 ggtgaaatct ttggtctcat tggtcacaat ggggctggca agacgacaac aatcagtatc
      661 ctgacctcta ttatcgaagc aagctataga gaggtcttgg tcaatggtca gctgctgagt
      721 gagcatcgta acaccattaa aaggcaaatc ggctatgtgc ctgattcacc ggatattttc
      781 ttaaacctga cagcctatga atattggcag tttcttgcta agatttatgg cgtcagtgag
      841 gcggatacca aagctcggat tgaggagctg acgcagttat ttgagctgac gcaggagatg
      901 cacaacacga ttgataactt ttcacatggt atgcgtcaaa aggtcattgt gattggtgct
      961 ttgatctcca accctagtat ctggatcctt gatgagccct tgactggact ggatcctcag
     1021 gcttcatttg atctaaagga aatgatgaaa gagcatgctg cttctggtaa tacggttctt
     1081 ttttcaacgc atgtcttgtc ggttgctgag cagctgtgtg accggattgg gattttgaaa
     1141 aaggggaaat tgatttttgt tgggacagtt gagcagctaa aggctgatta tcctgataag
     1201 gatctggaga ctatttacct tgaattggca ggacgtcaag cacaggaggc atagtggtat
     1261 gaattggtca actatttggg aattagtcaa gattaatatc ctttattcca atcctcagtc
     1321 cctgacagct ttaaagaaaa agcaagaaaa ggctcccaaa gagaacttca aggcctacaa
     1381 gagtatgatc agacagcaag ccttgatgat tgctctgttt ttagtcattt acatctttat
     1441 gtttatgggt gttgatttta gccaatatcc gggactgttg tcactttata ttgctatttt
     1501 ctttgttatg gcaactgtta atgcctttac ggcaatgtat gcggtctttt atgagagtaa
     1561 tgacgttaag ctctatgttc atctgccgat aagatctgag gagcttttca ttgctaagct
     1621 gatttcctca ttaggtatgg gatccatatt tttaatgccg ctgctaagcc ttttcgtgat
     1681 tgcctactgg cagatcattg gaaatgcttt ggcgattgtg ctagcgttta tcctgtttgt
     1741 ggtgctattt gtcagctcga ttgtttttgc tctgtatctc aatgcttgga ttggcaggat
     1801 tattctgagg agtagtaagc gcaggctgat ttcagcggtt ttgatgtttg cttctacctt
     1861 tggtgctcta ggcttgattg tatttctcaa tatgactaac aatcagcgaa tgatggctga
     1921 tcaagccttt tcagatcgcc ctttgattcc ttattttagg ggcagctatg atgttgttgt
     1981 ggcaccgttt tccagtcagg ctctgcttaa tttttggctt cccttgcttt tggtcatgct
     2041 gatgctgtat ggtcttgtta gacggatcat gccggcttat tacagagaga ccctctatgt
     2101 tggtggaaaa gctaaaaatg cagcagtggc gcgcaaggcg gctgcatctg atcgtcagca
     2161 aagtctacag cgattgttga caaagcacca tcttgcaacg ctgcaaaatg cgacactatt
     2221 gacacagact tatctgatgc ctttgattta tgtgatgatc tttatcactc ctagtgtgac
     2281 aagtggtgca caattttcaa gctacattac cgatgagtac tttggtattg cgcttttggt
     2341 gggggtgctc ttgggaagta tatgtactgt gccgaccagc tttgttggtg ttgggatctc
     2401 tcttgaaaag gacaatttca cctttattaa gaccctaccc attagcttaa agggcttttt
     2461 gcttaacaaa tttcgcttgc tgatagggct gcaaatcctt gctcccttgg tggtttatgc
     2521 tcttattgga ttgtttgtat taggctttca ccccgttatt gtcctatcct tttcattagg
     2581 ctttgtcttg atgggaatca tacaagggca attgatgttt aggcgtgatt accgcatgct
     2641 ggatctgaaa tggcaggacg tcacccagct tttcaccaga ggaaatagcc aatggtttat
     2701 gcttgggctg atgtttggcg acttaattgt tggtggcttt ttgattgttt tagcgattat
     2761 gtgtgctacc attagtcagc agcctcttct tgtgagcatt gctgtgagcc ttattcttct
     2821 tagctgtttg ctctttgccc agctctggat tcaaagaagc ttttggaaaa atctgaataa
     2881 gatgtaaata gctctggggt attaattctc cagattggcc aaggtaagat gtgacgaagt
     2941 tttggttcta gctcaaatag tgagagtaat tgcagtaact atatgttaaa agctagagca
     3001 gctattgaaa aaagaaagca aaaagcttta gcaagctagc agtgccctac ggtgctagct
     3061 tgtggggcat caagatcaag ctcctaaagc tgttagtgat gttgctcgac acatagcttt
     3121 gggagcctca cgaaaaaagc taactcaact gttgcagctg ctagctttag atcaacagtc
     3181 atgtgctaaa ccattttcaa aaagagcttt tatgacgttt ggattgaagt gacattctga
     3241 taacccatca caagcatgct ggctttatca catcttaatg gcagttccaa atactactaa
     3301 tttaggctag cttcttagaa aaagctagcc taactatttt aactaaaaag tcaaggactt
     3361 gtgctttgac cttttgttgt tttcagtaac tgagtagcta ttttacccat atatgaaagg
     3421 catcatcact cacttgtttg ttaaagatag cttgatggtc attgatatgg tatccgatta
     3481 atgtatgacc agctaatatt aatagggtgt tctcgtcaat ttgtttgaca tcttttaagt
     3541 agtcactttc aatggataaa ccaaattgag ataagtcaat aaaagtagac gttttatcat
     3601 tgaggtgaaa caggctaaac ccaatttttc cagcttcatt tttctcatgc tctattgcca
     3661 gtgtatcgtg acccaaatca aaaatgttga ctggagcaat ctcagtgaga tcgaaaaaat
     3721 gtttttgacc tgactgcata tcataatgga aaacctgccc taaaacggtt ctctccttgg
     3781 taacattgtt tcgatagccg cttaaggcgg tatagagctg cttttctttg acaatgctat
     3841 catggaaaaa gtaagtggat tcaggctgtt catagagcag ctctttgttt ttcatagcta
     3901 attgcccatt tttgatagat agcgtatata agtaggttgg gtagttatcc ttgattttca
     3961 catctgttcc taagaggtaa atgtcatctc catcaactga aaaatcgcta gcaatgacag
     4021 aatcctcaaa gatatgctta tcaatttctt tgagcttagg atcaaaaaca gcaataaaac
     4081 tatcgtcg
//
LOCUS       DARYLJ010000085         3634 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYLJ010000085 DARYLJ010000000
VERSION     DARYLJ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3634
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..1726
                     /locus_tag="TU746_001892"
     CDS             <1..1726
                     /locus_tag="TU746_001892"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HEL0892192.1"
                     /translation="SYLSFNKLKAVGILDPIDYLQRLNGKIGYYTKNYSPLGDCMYLT
                     QENTEKIDNIRQIIEDWNNNQLLTEYEYFYLLNALIEAIPYVSNITGTYGAFLKHWDN
                     RALHSLTLAEETIFDNYRPNKAFNENANELVKKIKADIVYIDTPYNARQYASNYHLLE
                     NIARHQKPILKGITKIFDWKTLKSDYSTKTKALKAMEDLIANINASHIILSYNTEGII
                     SEEDLTLLLQRYSFNNQIDVKRIPYRKYQSKKKSQNKDLYELLFYIQRKPINNRFKSQ
                     TKKKAAIISQKKYIKSPLNYIGGKYRLLNQIIPIFPRHINTFVDMFSGGANVGINVPA
                     KKHIFNDMNYRINDMFRYFQSHDPLEILEQIEHRISEYQLSKTNEQGFLTFRKHYNTH
                     PNPLDLYVLSSYSYNYQFRFNNSMEFNNPFGRNRSHFSENMKSNLLNFVARLHRLDAT
                     FSDQFFSDFDISTLSIDDFVYLDPPYLITTGSYNDGNRGFTNWGEKQEIEMYQLIRDL
                     NKKQIKVALSNVLVHKGKHNDLLEQFVQDESLYLTTLNYNYKNASYNTRKEDSIEVLI
                     TNYKPNPK"
     gene            complement(1747..3360)
                     /locus_tag="TU746_001893"
                     /pseudo
     CDS             complement(1747..3360)
                     /locus_tag="TU746_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
BASE COUNT         1272 a          701 c          491 g         1170 t
ORIGIN      
        1 ttcttaccta tcctttaata aactaaaagc agtaggaatt ttagatccaa ttgattatct
       61 acaaaggctt aatggtaaaa ttggatatta cacaaaaaat tactctcctc taggagattg
      121 tatgtatcta acacaagaaa atactgaaaa aattgataat atcagacaga tcatagaaga
      181 ttggaacaac aatcaattac tcacagagta cgaatatttt taccttttaa atgctttgat
      241 agaagctatt ccttatgtta gtaatattac tggaacctat ggcgcttttc tcaagcattg
      301 ggacaaccga gcgttgcatt ccttaacatt agcagaagaa actatttttg ataattatcg
      361 tcctaacaaa gcgtttaatg aaaatgctaa tgaattagtc aaaaaaataa aagcagatat
      421 tgtttacatt gataccccct acaatgctcg acaatacgca tcaaattatc atttactcga
      481 aaacatcgcc cgacatcaaa agccaatttt aaaagggatt actaaaattt ttgattggaa
      541 aactcttaaa agtgattatt caacaaaaac aaaggcttta aaagcaatgg aagatttaat
      601 tgctaatatt aatgctagtc atatcattct aagttacaat accgagggta ttatatccga
      661 agaagattta acacttttac ttcaacgata ttcgttcaat aatcaaattg atgtgaaacg
      721 gattccttac cgaaaatatc aatctaagaa aaaatctcag aacaaagact tatacgaact
      781 tcttttttat attcaaagaa agccgataaa taatcgcttc aaatcacaaa ctaaaaaaaa
      841 ggcagccatc atcagtcaaa aaaagtatat aaaaagccca ttaaattata tcggtggaaa
      901 atatcgactg ctaaatcaaa tcattccaat ttttccccga catatcaata catttgttga
      961 tatgtttagt gggggggcaa acgttggtat caatgttcct gctaaaaaac acatctttaa
     1021 tgatatgaac tatcgcatta atgacatgtt tcgatatttt caatcacatg acccacttga
     1081 gatacttgaa caaattgagc atcgaatttc agaatatcaa ctcagcaaga ccaatgaaca
     1141 aggcttttta acattccgaa aacattataa tactcatcca aatccactag acttatacgt
     1201 actatcgtct tatagctata actatcaatt tcgctttaat aactcaatgg aattcaataa
     1261 cccattcggc agaaatagaa gtcattttag tgaaaatatg aaatccaatc tactcaattt
     1321 tgtagctcga ctacaccgtt tagatgccac tttctctgat caatttttct cagattttga
     1381 tatttctaca ttatcaatag atgattttgt ttatcttgat cccccctacc tcataacgac
     1441 tggcagctat aatgatggaa atcgtggctt cacaaactgg ggcgaaaaac aagaaattga
     1501 aatgtatcaa ttaataagag accttaacaa gaaacaaatt aaggttgcac ttagtaatgt
     1561 tcttgttcat aaaggaaagc acaatgattt acttgagcaa tttgttcaag atgaaagtct
     1621 atatctcacc actttaaatt acaattataa aaatgcttca tacaacacaa gaaaagaaga
     1681 tagcattgaa gtattgatta ccaattataa accaaatcca aaataataaa agcatagttg
     1741 aattagctat gcttttacaa attcaatttc tttattttga aaataagatg gtaaatcgga
     1801 aatatgcagt tgtcctttaa gaaccaaatc tgctcccaaa agcaattgct ctacattgag
     1861 ggctgctccc ttaatttgtg tttcattaga ggtataatca agctgctctt gaaattttcc
     1921 aatgaattta cttgacaccc acataaaata aaactcttct tgtggaatcg tatctggaaa
     1981 agcttcccac cactttatcg gattacgatt ttcatctcgt cgcttattat cctcaatata
     2041 ccgaatcatt tcatcagcct gattgataga tttagaataa ccttttccat aagcctttgt
     2101 atctacaatc acaccaaaac gatcttgata gagtaaacca tctggctttc tgccaccacc
     2161 taaaagctta gaatgcaatc tatatacatt tctaaataat tccattgtaa caatttcaaa
     2221 atctcgattt cgcttaccat cgtaagcaat atcaagcaat tcaatatatt tcattggtaa
     2281 attagtctct tttaaaaatt ttgccttacg cttttctgcc tgctcatcct ttaattcttg
     2341 tgtaatttct agttcaggaa tagaaaaatc gttgatctta tccttcaaag aaactctatt
     2401 gctagaaata tctatcctca aaccaaaata attcaatcct tgaatatctg ataagataat
     2461 ctccagttca tcgtaaaaac ccttagccct tagtttatct aatagaatag ccaaagaatt
     2521 agtttcttgg agaaacttga cgatataagc tctccgagta cgaacatact cgcgattatt
     2581 gccatgagtt gcaaaaaatt cccacatcac aaatttttca agcttgctat gcttagaatc
     2641 cccctgagct tgtcgtaaag catgaagacc acgaccatta attttataac cttgaaatcc
     2701 atctttttca ccattagtaa aggtacgctt aatcgtttgt gaatcaacca aaccaacatt
     2761 ttttagccaa ttacaaatac cgcgtgcata tttatcactt gttccttcta tatcagcttt
     2821 aataagtttt ttctctgatt tagtggcaga tcctaaccaa tcaaacataa tatcttcatt
     2881 ataggaagta aagccttttt caccacgaaa accaagctgc tcacctaaat aatatttagt
     2941 acaataagta ccgctatcag ccaataaaga taagatttgt gtagctggcg ggtatgacaa
     3001 cagtgccttt cttaaaatag cagtttcttc ttccgaatta attattgccc tagaaaaatg
     3061 caaccccttc gaagtaattg aaaacatatc cgtttctcta tctaccgaca caaaattcag
     3121 gctaacagcc catcttaaaa aaccatctga tgtccaatta tccgtccaag ttttacctgt
     3181 attttttgcc tgttgaggta cgatgctgat ttgaatcaaa gaatctgcca ttgcatctga
     3241 acgctttcgg ggagatttgt tattcttatc ctttgatgtt ccaactaatt ctaaatatga
     3301 aaatgattga atcccattaa tcagtttgtt tctgagtgat tctcgtggta cttcaaagaa
     3361 atctgtaccc aaccataagt tcttattttc ataagagctc cttaatctta tacttattat
     3421 ctttattata gcatataatt aatccttcca gttagcatta tcacaaagca acaacatttc
     3481 ttatttaatg gggctactat gtagctattt taatacatgt ttttacctca cgaaaacacc
     3541 cccacttgtc aagtctgtaa ctgtactgac ccccaaaagt tggacacgac atattagtga
     3601 aaggatttag ttctgtattg cacagggcta agtc
//
LOCUS       DARYLJ010000086         3347 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYLJ010000086 DARYLJ010000000
VERSION     DARYLJ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3347
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(360..1334)
                     /locus_tag="TU746_001894"
     CDS             complement(360..1334)
                     /locus_tag="TU746_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL0892193.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
     gene            complement(1335..1793)
                     /locus_tag="TU746_001895"
                     /pseudo
     CDS             complement(1335..1793)
                     /locus_tag="TU746_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            complement(1993..2691)
                     /locus_tag="TU746_001896"
     CDS             complement(1993..2691)
                     /locus_tag="TU746_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL0892194.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            complement(2684..2920)
                     /locus_tag="TU746_001897"
     CDS             complement(2684..2920)
                     /locus_tag="TU746_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL0892195.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
BASE COUNT          978 a          835 c          623 g          911 t
ORIGIN      
        1 gcataatgac ttcctccgtt tgtacataga tcatctcatt atagcacaaa tggccttaat
       61 ttgcagaaaa aacaagaatg ctgcaatagt ccttagcttc agacaaactc ccttacctac
      121 cttgactcct tttttaaagc agctagctag agctgcctgt catcgctaag tatcaaagat
      181 gtcgtaaaca aagcaagctg caaattagac ccctcactat gaaaaaagca gttaggctcc
      241 gcgattgaaa gactccgagt catcaggaac aagacctgta tctgatagaa caagaagggt
      301 catcacttct taagacagct agcaaaaaag atgacttagc ttgtagccac tagctactct
      361 tagctatcgc tttctagcga agctgctgcc tgctctaaaa cagccatgac tgccttgctg
      421 tgctccaagg cctgctctgc cctttccatg tccttattag agataatatc tgaaaaggca
      481 ataaattcat cgtacatgcg atgagacggg tggttaaagt tgacggtcct tgcttgctca
      541 cctcgaatgg ctagtaaaag ctctggtaca gcattaggag cacctaaaac agaaagaaag
      601 cctttattcc cctgaatcgt agagacaatc tctgcactgc aatccttagc cccaatacaa
      661 acagccttaa atcgctcata atccatcagc aaaacaccag aggtgtcaac ctgccgctcc
      721 atattagcta ggtactgaac cgtttggggc ttgccaaata agccaacgag cagatggata
      781 ttataaatat tcaaatcacg caaggcccct ccaccctttt taggatcaaa ggctggtgca
      841 atctccccac gcttaaaggc atcataacga gaggaatatt gagaataatt gcactccaca
      901 agcttaatct ctcctaactc agtcaagtga tccttaataa attgggtgtt tggcaaatat
      961 tggttggtaa tagcttctaa taatatcagc tgcttagctc ttgcaatgct gcttaaagca
     1021 tcaagctcct tggctgtcat ggtaaatggc ttttcacaaa tgacatgctt accagcctca
     1081 agggcttgct tagccacttc aaaatgcaaa tgatttgggg tggcaacata aaccgtatcc
     1141 acctcttcat tttttaggac ctcggctagc tgacagctgg cctgttgaat gccaaaggcg
     1201 tcagcaagcg cctctgcggt ttcaagacta cgaggcgttg aaacaatcgc cattaagtct
     1261 atgcttttga tctcctttaa aacaggcaaa acctctttga caatcatgcc tgtaccaaca
     1321 agggctaatt tcatttattt ctccttttta gcagcttcag ggtaaaccct ctgaaactcc
     1381 tctaacacaa taaggctatc ctcggtaaag cgtaagccta cctcttcaaa ataaggtctg
     1441 aaaaaggcct catgaagcag ccgccattct tccaagcttt tatcaccctc tccttcctta
     1501 taggcatgct ctgctggcac gtccttgaag ggaacaagac taaccttagt aatctggata
     1561 atacagatcg cctgatccct actatccaaa atcacgtcat agctgccctc tttggaaagc
     1621 ggctcatgat caggctcata tcagtcatag gcagaggctg tagctgtttt agtgccttct
     1681 agcactaatt gcgctaataa atcaggctca gctccaaagg cccaggcctc agctagatca
     1741 ccaacaccag gattgatttg ctggtattga gaccataatt cttctgcagt catgttatca
     1801 cctctattga tcgaatcctc tagacaggta ggctcctgct gtattaagca aacctactag
     1861 gcactaggct tcatggaaaa aacttcatca gctccctctt agcctgtgac aagattgctt
     1921 gatacagcta tcaactgtca ccctctgtac agacaagcca gatcttgcta ggccttatgt
     1981 cgatgtgctg tttcacttta agctccaacc gccatcaatt ttaacaattt ctccctgcat
     2041 ggcgctagct tttccagatg ccaaaaacat ggtcagctcg gctatttctt cagccctaag
     2101 ccaacgaccg ataggagtct catcagccac ccactgggct aagccacctg gctcaaagtc
     2161 tgtggctgtc attgctgttt gcactgcgcc aggggcaatg ccaaaaacct gaatgcctgc
     2221 cttggcataa tcaagcgcta gctgtctggt aaaaccagcc agagcatgct tgctggaggt
     2281 ataggcagct ccgccgccac ctgccatgaa gctagcaata gagcacatat tgatgataat
     2341 acctgattga gctgtcagca tctgtgccaa atagtgacgc gtgatgcgga cagctgcaaa
     2401 gaaattgacc tgaaagagag cctcaaaatc agcctgtgtg gtatcaagca agggcttata
     2461 ggcatcaaga acgcccgcag tatgacacaa cacatcaacc ctaggcacag cctcaaaaag
     2521 ctcagctaaa tcacctgtaa tatctaactg taaaaactga aaatctcctg ataaatcagg
     2581 cttttttgcc ttgtcaaccc cataaacagt aaagccattt ctcaaaaaca ggcgcgcctg
     2641 tgccagtcct atgcccgatg acacaccagt gatcagcacc cgcttagtca tagacctcta
     2701 cccagtcagt agcaagaacg tcgcagggag tcggtgccca catggaaaag ccctcgccag
     2761 ctcctgacac gttaatcaaa aagtaaggcg tcacctcaag tgccacacca ttttgttcaa
     2821 tgctatcaaa cagctgaaca tagttttcag cgcctcccca gcccttacga acgtattttt
     2881 tcttggcctt caagcctggc aaaatctctt caaatgtcat ggttttctcc ttttataggt
     2941 ctacatcata gcatgagctc ttttaatgat cattatacca atttactcag cttttgtaag
     3001 cttaaagatc acgaaagtcg caaacgtaca agtttgcttt gtttttagat aaggattcat
     3061 catcttaact aattatgaca taatctaagt gatatgaaat cctttgtaac ccacaccagc
     3121 tttttataat acactaacct gagtgtcttt aaaactgcgg ctgtaattct tgattaagct
     3181 aatacagcat gtctagccag tatatgaaaa taattggaat tattttcgtt agaatgttag
     3241 actattttag ataaagcgtg ttcaatgaca ttattttttg tataaatcaa aatatcccca
     3301 aactactatt aggattattt ctttactttt agtcactttt aataaac
//
LOCUS       DARYLJ010000087         3255 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYLJ010000087 DARYLJ010000000
VERSION     DARYLJ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3255
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..1555)
                     /locus_tag="TU746_001898"
     CDS             complement(<1..1555)
                     /locus_tag="TU746_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0892196.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSVTFPEAANTYNGA
                     VLVVKDMETLKDIQDSIQSINHTGGRASISAYADLTKADLRSISDDKGIISDGDTVIG
                     HIETKKEYLR"
     gene            complement(1558..2310)
                     /locus_tag="TU746_001899"
     CDS             complement(1558..2310)
                     /locus_tag="TU746_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892197.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2641..3120
                     /locus_tag="TU746_001900"
     CDS             2641..3120
                     /locus_tag="TU746_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL0892198.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT         1036 a          605 c          609 g         1005 t
ORIGIN      
        1 atcggaggta ttccttttta gtttcgatat gacctataac agtatcacca tcactaatga
       61 ttcccttatc atcactaata ctcctaagat cagccttagt taaatcagca taggccgaaa
      121 tgctggccct tccgccagta tgattaatgc tttgaatgct atcttgaatg tcctttagtg
      181 tttccatatc tttgaccaca agaactgcac cattataagt gttagctgcc tctgggaagg
      241 ttactgatgt taaatttttg acattggtat atgatttgcc caaaatatcc agctgtcgta
      301 attgactatc ccctctttgc ttaaagaagg cagtctgatt gtcctttaat tcaggcaatt
      361 gattgcccaa ggcgcggaaa tcatcttgag tgactaagta gacatagcct gtagtgactg
      421 gactaggatt tagcaaggat tctttggtta ctacaatggt ttctttttgg gatacttcaa
      481 aagaaaccat gctactataa tagactagaa aatccgaggc aggcttattg gtcttttcaa
      541 caataagtct gttaaaaacc tctttttgat tgtcaatctc tgaattatca aaattaatat
      601 gagtattttt aggaaaaagc tggttagaca ttgcctcgct attagcataa agcgcagttg
      661 ttgttgctat tgcaacaaag gccataacag ctaagagggt aatatttgcc aagcctacag
      721 cattttgctt cattctaaaa atcatctgag aggtgctgac aaaatgctct ggctggtaaa
      781 aataagcctt gttttgacga cgacgcttta agtgccaagt cataaaggaa atgtaaaaga
      841 gataggtccc gataataacg ataataactg ctataaaaaa ccgatataaa gtgtctaatg
      901 ctgtcagctt tgtcgatgat aaggagatgt aatagccaat actaagcaat atgatggata
      961 aggctgctag taataaatta ccctttggct ctttttcacc ctgttcttta tgacgaaaga
     1021 gcattaaggg agaggtcttt ctgattttaa tcaagccaac aacctctaat aaaccaaaga
     1081 tagcagcaaa gattaaagtg gtgtaaataa aagcaacggg attgatttgt aattctaaat
     1141 ggactgctcc gaccagatta gcgaaaatca aataaaagac gtgtgaaaaa atagctgata
     1201 ggatacttcc tacgactact gtccctaagt acataaaaac aagctcgatc gttgagacta
     1261 aaccaacctg ctttttattc attcccaaaa tattgtacag accaaattct cgacttcttt
     1321 gctttagtaa aaaattatag ctataaatct ccataatagt ggcaaagatg attaaaacaa
     1381 agattgctag tcctaatagc ataaacccat gtctcatcga ttctgatacg gggctcatca
     1441 tgataatcaa gacaatacaa ttgagcatat ataaaacagt gcttgccagt aaaaaaggag
     1501 ctgtgacgga taaggacttt cgtagattat tccaagctag tttgagataa aacatcttta
     1561 ttcacctcct aaaagaccgg ccatggcaat cgagatgtct ttgctaaatt ctaaattcgt
     1621 tttatttcca cgatagattt ggtggaaaat acggccgtcc ttgataaaca gtactcgctt
     1681 agcatggcta gcagcattgg cagagtgtgt taccatcaag agtgtctgac cgtctaggtt
     1741 aatggcctca aaaagattga gaatatcctc tgaattgcgg taatcaagtg ctgctgttgg
     1801 ttcgtcagct aataataatt gcggattggt gattaagctt cttgcaatag caaccctttg
     1861 cttttgacca ccagaaattt caaatggacg tttatctaaa agcgtttcaa tgcgcagctt
     1921 aggggcaatg atgttgagcc gtctttccat ttctttaaat ggcttacggt ttaaaacaag
     1981 gggtaaaaag atattatctc tgatcgatag ggtgtctagg aggttaaaat cctgaaaaac
     2041 aaagcctagg ttttgaagtc ggaaattagc taggtcaccc tccttaattt ttgtaatgtc
     2101 agtgccattc aataaaacag atcccttggt tggtttttcc agagttgcca gaatatttaa
     2161 tagggttgtt ttccctgagc ctgactctcc catgatggca ataaactcac ccttgtcaac
     2221 cttaaaatca acatcttgta aggctctagt ttcttccttt gaaaagcgtg tccgaaaaac
     2281 cttctctaaa tgattaattt ctaataacat atgaaactcc tttgtgtcta ttatactctt
     2341 ttagctttaa atatagccac tatcgtgacg tatttagcta gtgatgcatt tagtgccttt
     2401 tgtcagcctt aaccactcct tctttcatga agcagcccag ctctcaacaa gaatcgtctt
     2461 agctgactga acctattgct ctaaactctt ttttctttac agcttatagt ttaccctaat
     2521 taatagtctg gttagcttac aagatttgat gggtgactta cagatttgta agttttataa
     2581 catcattttt cttatcattt tgatataatg aaaggagaat tctatttagg agaagcgtca
     2641 atggctaaga aaatcaaaaa aacgctaggg actgtcggaa agctgttttc cattatccct
     2701 gataccactg aaattatagg aaaaacgata gataacaccc gtcccattat cgaaaagcat
     2761 atggaacaaa agcatgaaaa ggaaatgcag ctaacgcttt tagatgatgt gattaattta
     2821 cctgttgata aagcgcaaaa gcatctggaa cagctaggtt ttgttgtcgc actattgccg
     2881 gtcaagccta gtaaaaaatg gatacatgct agcttaaatg aggttgtttc catgtcacct
     2941 aagcctggaa agcataagct gggaagctta gtaaagcttt attatgttac tgtagatgtc
     3001 cttgagaaaa gtcaggctat tttagatcaa gagaccctaa aggctgtcga acgaaatcaa
     3061 aaaatcgctg ataccatcga agctgttaag caaatcaagc ttccttttaa aaagagataa
     3121 ggctatactg taaaaaataa gctgataccg ttaggatcag tttatttttt atgttgtgac
     3181 tttaagtcta tctcgcttag caggtgccaa acaaataaac cacccgttat gtaccgacct
     3241 tcaatggtta aagtt
//
LOCUS       DARYLJ010000088         3177 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYLJ010000088 DARYLJ010000000
VERSION     DARYLJ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3177
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TU746_001901"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TU746_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL0892199.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1245)
                     /locus_tag="TU746_001902"
     CDS             complement(664..1245)
                     /locus_tag="TU746_001902"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL0892200.1"
                     /translation="MCDACQRHFCRITQPTCSNCYQYRHEGACQDCIAWKRQGYQVDH
                     QSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKAYTLVPVPVSKQRYDE
                     RGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNRYRLKKGAALPPKILL
                     IDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TU746_001903"
     CDS             complement(1473..1658)
                     /locus_tag="TU746_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0892201.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TU746_001904"
     CDS             complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TU746_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL0892202.1"
                     /translation="MRIFLRQNCRLVNMSTTFFIVVLSLVVFSVRMVSAEGTISIKDI
                     YSPRWDVDKTLSPTTLREIYNRDTIKKENKPVTGKRGTQVIIDAQHKTKVWEFDDYNF
                     IISSNLYPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIY
                     MNVFIDGHKKDETSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSKVLSGNW
                     EFHGSGENEEGADLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN"
     gene            complement(2835..>3177)
                     /gene="spek"
                     /locus_tag="TU746_001905"
     CDS             complement(2835..>3177)
                     /gene="spek"
                     /locus_tag="TU746_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL0892203.1"
                     /translation="DVKPEEKAIYINIFGEKELRTLTAKDKITFKNNIVTLQEIDVRL
                     RKSLMGDSKIKLYEYDSLYKKGFWDIHYKDGGIRHTNLFTYPDYTDNETIDMSKVSHF
                     DVYLNEEFSKN"
BASE COUNT          947 a          648 c          477 g         1105 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa ggtaacggga gatttttcaa aagttatttt
     2041 atatttcgag gtctcatctt tcttatgccc atcaataaaa acgttcatgt aaatcgtttt
     2101 tccagctcct tttctctcat taactttaac gagaccacca ttgattgaat gtatttgatc
     2161 ttttgaaaat acttcagccg ataatgcaag accaaaaaca tcgacattat ctccaacatt
     2221 aaatttacct tctacagatg ggtataggtt acttgatatt ataaaattat aatcatcaaa
     2281 ttcccatact ttagttttat gctgagcatc tataataact tgcgtccctc tttttccagt
     2341 aacgggttta ttctcttttt ttatagtatc tctattataa atttctctta aggtagtagg
     2401 ggataatgtt ttatctacat cccaccttgg agagtatata tccttaatac taatagtccc
     2461 ctccgcagaa accatcctaa cagaaaatac caccaatgac aatactacta taaaaaaagt
     2521 agttgacata ttaaccaaac gacaattctg acgtaaaaaa attctcattt atcttattat
     2581 tctccttaat aaatcaatat agctgtgaaa ctatgttttt tgaacttgaa cctcaaaatg
     2641 cttaaatcgg aagtacttga gcagacttct taaaagataa taaactgatt ctataacgca
     2701 cagaaattaa tctgagcggt tttatcatat tcctcggttg accgatagtg atgcctagaa
     2761 gtctactaaa accgtctaat tcatcaaaat ctatttaaat agactaaaaa ttaaattaaa
     2821 atagcattcg accgttaatt tttagaaaat tcttcgttta agtaaacatc aaagtgacta
     2881 actttactca tatcaatcgt ttcattatct gtatagtcgg ggtaagtaaa taaattggtg
     2941 tgtctaatgc caccgtcttt ataatgaata tcccaaaacc cttttttata caaagaatcg
     3001 tactcataca attttatttt gctgtctccc atcaaacttt tcctaagtct aacatcaatc
     3061 tcctgaagag ttacaatatt atttttaaag gtaatcttat ctttagctgt taatgttcgt
     3121 aattcttttt caccaaaaat attaatataa attgcttttt cttctggttt tacatca
//
LOCUS       DARYLJ010000089         3014 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYLJ010000089 DARYLJ010000000
VERSION     DARYLJ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3014
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(214..1050)
                     /locus_tag="TU746_001906"
     CDS             complement(214..1050)
                     /locus_tag="TU746_001906"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892204.1"
                     /translation="MNNLYATINKLNKVEQSVFLVINDIIDNNTVFPDVNARNSLKKI
                     AISTLGDRTFSTPYDFISEHIYNNADLNSVQDDEMLVKNIEILKNYALQNNFENFDYS
                     LFIKNLNKIHRHYKLALIQKNFILRTTTEVEERAHDLKDKTKAIEQKMFKFDEIKSSI
                     YTDFIAILGVFSAFVFVMFGGIDVARAIFDIGSDLQTLDLSRMITIASLMLIGILTLM
                     YSLLLWIARITGKNFGNCYSSKCDNGCQHKWRHFLMRHSFYFSLMGLLIVVILFSHYV
                     FK"
     gene            complement(1054..1596)
                     /locus_tag="TU746_001907"
     CDS             complement(1054..1596)
                     /locus_tag="TU746_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL0892205.1"
                     /translation="MTEALFVANYIIEYCNDHNLEINNLRIQKLLYFINARNLVENGS
                     PLFQDKIEKWKFGPVVPKVYHEYKRFGASTITKDDISAQIWKFNFEVSPFGEESPIEV
                     LTYNKEEFSDSQIQLIESTILALKKYSTFKLVDLTHEDDMWKSDNQLIMSGEKGLTYD
                     NNEIRDFFMSHIESQIWNNI"
     gene            complement(1731..2927)
                     /locus_tag="TU746_001908"
     CDS             complement(1731..2927)
                     /locus_tag="TU746_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0892206.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYH
                     AVIGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWDKEALKTNKEVTMTTA
                     NEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLWGNAIDLLNSASAQG
                     LEIIYNAPGVNPRAGDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHTKQTVDTAPQTSDTIVETPKTGTFTVDVAEINIR
                     RWPSLASEVVGSYKQDDTVSFDSEGYANGYYWISYVGDSGKRNYLAIGQTDKDGNRIS
                     LWGKLN"
BASE COUNT          950 a          608 c          476 g          980 t
ORIGIN      
        1 ataaaattaa atatagtggt aattttaaat caacgtattt gaaatatttg gtagctacta
       61 tttcctgaaa aagaaataaa caaacgggcg tatgacgggt tctgcattcc tccttcatag
      121 gttaataaaa attgaagatg aaagaaagaa attaaaaaaa ataattcctt aaaaaacaca
      181 aaaaaccgcc ctcaatcaag agagcggttg gttttattta aacacataat gactaaaaag
      241 aattacaaca attagtaatc ccattaaaga gaaatagaaa gaatgtctca tgagaaaatg
      301 acgccattta tgctggcacc cattatcaca ttttgacgaa tagcagttac caaaattttt
      361 gcctgtaatt ctagctatcc aaagcagtaa agaatacata agcgtcaata taccaattaa
      421 cattaagctt gcaatggtaa tcattcttga taagtccaga gtctgaagat cactaccaat
      481 gtcaaatatc gctctcgcta catctatgcc accaaacata acaaaaacaa aagctgaaaa
      541 cacacctaag atagcaataa agtctgtgta aattgatgat tttatttcat caaacttaaa
      601 cattttttgt tctatagctt ttgttttgtc tttgaggtca tgggctcgct cttccacctc
      661 tgtagttgtt cgcaaaataa aattcttttg aattaatgct agtttataat gtctatgaat
      721 tttatttaaa tttttgataa acaaagaata atcaaagttt tcaaaattgt tttgtaatgc
      781 ataatttttt aaaatttcaa tgtttttaac gagcatttca tcatcttgaa cactgtttaa
      841 atcagcatta ttatatatat gctcagaaat gaaatcgtat ggtgtactaa aagttcgatc
      901 gccaagtgtt gaaatagcta ttttttttaa actattgcga gcatttacat cagggaaaac
      961 agtattatta tcaataatgt cattaattac taaaaaaaca gattgttcta ctttgtttaa
     1021 cttattaata gttgcataaa gattattcat ttgctaaata ttattccata tttgagactc
     1081 aatgtgcgac atgaaaaaat ctcttatttc attgttgtca taagttaaac ctttttcacc
     1141 agacattatg agttgattat cagatttcca catatcatct tcatgtgtca aatctactaa
     1201 tttaaatgtg ctatattttt ttaatgcgag tattgtactt tcaattaatt gaatttgaga
     1261 atccgaaaat tcttctttat tatatgtcaa tacttcaatt gggctttctt ctccaaaggg
     1321 gcttacctca aagttgaatt tccaaatctg agcagaaata tcatccttgg taattgtaga
     1381 cgctccaaat cttttatatt catgatagac ttttggaaca accggtccaa atttccattt
     1441 ttctatctta tcctgaaaca gtgggctgcc attttcaact aagttccgag catttataaa
     1501 gtataaaagt ttctgaattc ttaaattatt tatttctaaa ttgtgatcat tgcaatattc
     1561 aatgatgtaa tttgctacaa acagtgcctc agtcatccag tccacctcct ttttttaatt
     1621 ataacatatt tgtcaagtac tatatcttgt tagctaactt tttagctaac actacatatt
     1681 gattttgata ataaaaacag cccccgcaaa agcgagggcg tttgtcttat ctaatttaat
     1741 ttaccccaaa ggctgatgcg attgccatct ttatctgtct gtccaatagc taggtagtta
     1801 cgcttgcctg agtcgccaac atagctaatc cagtagtagc cattagcgta gccctcgcta
     1861 tcaaaactga cagtatcatc ttgtttgtag ctacctacta cttcactcgc taggcttggc
     1921 caacgtctga tattgatttc tgcgacatct acggtaaaag tacctgtttt tggtgtctct
     1981 acgatagtgt cagacgtttg cggtgctgta tctactgtct gcttagtgtg atcaaccggt
     2041 aatctaatcc agccgacaac accagtaaag tcacgagtat taaagcgagc gggaccacct
     2101 acctgaagac tatcccagtt accgtcaata ttttgctcaa cggttttaat agtatagcca
     2161 tcactgtcct caataacagc tcccgtgtgt ccgtagggac taccagctac ctccatgaca
     2221 aataagtcac cagctctagg attgactccg ggagcattat atatgatctc tagcccttgc
     2281 gcagatgcac tatttaacag gtcaatcgca ttaccccata aatcaatgcc gaaccagttt
     2341 ttgacgataa aacatggcaa gtccgcacac tgcgtcccaa aacagccatc tttatcaaca
     2401 cccatgcctg aattggctag gtcgacacag tattgtacaa tctcatttgc ggttgtcatc
     2461 gttacctcct tattagtttt taaggcttcc ttatcccatt tttgcaagtt gttttcctca
     2521 atcaactgga taagcagctc tgcataatca cttgcagtgg cataaccagc tgctttaatg
     2581 gcatgacagg cctttttata gtcagtctct ccaattacag cgtgatagcg tggattatcc
     2641 actaaaaact ggccatgatc aaggattgac tcgtcccaac tatcataggc tctaaagcgg
     2701 tccacgagat ccgtcacgac acctggctga tactcctctt gtgtcttggt atcaaaagat
     2761 ttaccagacc atgagctatc tgccttgata ccaaacaatg cgttatgtgg ggcatacttg
     2821 ccccaaccac tctctaagat tgcctgcgct gcggttaacg atggcaaaat cttatgattg
     2881 tgccactctg cgataactgc gctttttatg tcgtctaaaa aggtcatctg tcctcctcat
     2941 ctaaaaacgg gtaaacaatc agagcaatca cagacacagg taaatatagc actgcgatta
     3001 ctatgactaa gact
//
LOCUS       DARYLJ010000090         2791 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYLJ010000090 DARYLJ010000000
VERSION     DARYLJ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2791
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..363
                     /locus_tag="TU746_001909"
     CDS             <1..363
                     /locus_tag="TU746_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="equibactin biosynthetic protein"
                     /protein_id="HEL0892207.1"
                     /translation="ESKVDFIIAVGVLNNAKNIEKTLSYIRGFLKDDGFLIIVEAVDE
                     SPEILISQVFMMSEPDDVRMKKNITFLKMEQWMEIFKNQRFELILFEPGYENYLENFN
                     QKLFVLKKNRGENHENRE"
     gene            347..>2791
                     /locus_tag="TU746_001910"
     CDS             347..>2791
                     /locus_tag="TU746_001910"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012873.1,HMM:NF021788.1,HMM:NF036900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HEL0892208.1"
                     /translation="MKIENKLIELYRKGLEVFIEGDKLKYKSTCGMPSEEDIEFLKIN
                     KTSIIDILNKNDGASRYSLDIDELPLTEIQSAYLLGRRNHFELGGVASHVYMEVILPL
                     LDIDRAEKVWNDIILKHDALHSIFTSNNTQKVLKEFAYYKIECNEGADIKEKIALTRD
                     KLKGKSYNADIWPLFDISVSQLDDNSLLHLSFDFLILDWASIWILLKEFEECYFDGKT
                     IMDNSYDLKEIRTSQLKLKHSSKYLSDKDFWERRIPFLPDAPLLPIKNKIVKNGFERI
                     QLRIDENTWSKIKSNISEIGVTQTSFLVTILALVLNRWSSNSEFTINLTTMNRPKEYI
                     KSDVVNDFTSTELLEFRMESLQPFYVLLKHIQQQMIEDLQHETFTGVEVTREVRKNVE
                     RRDAIFPFVFTSALGIKASEYKYISLQKEGLSETPQVLMDCQVMEVNHELIINFDLRA
                     DAFSKELSNSIAEDYSNLLNCFFDLEYFKKTLTEMYDENEMNDVLADKSDFDRVKYRV
                     IEHSKKFYNKNVFDAGEVRKILEERNLFSNQTMLKTLIEIKGDIIYKDFNNIPGNVVL
                     GEYHWILNKWEKHLDKAGFIKDNGDFYVVSEKGDELLKLNFDIELLKNSWDYSIGNSE
                     VIDYIIKTSENVINIFSGKIKPISILFPEGSSKIVESIYGNNIFCNYYNNIIRKAIEE
                     IIDLDSHKNINILELGAGTGNTTKEILKMLEMKNLDYRYIFTDRAKSFLANARNKFGN
                     YKNVEYKQVDIDNNLMEQSFFNDEINIVLAVGVLENAKKIKYTISSIEEVLKKDSWVI
                     ILEPVVDEPWILMTQLF"
BASE COUNT         1118 a          273 c          502 g          898 t
ORIGIN      
        1 gaaagcaaag tagattttat tatagctgta ggagtgctaa acaatgctaa aaatattgaa
       61 aaaacattga gctatataag gggatttttg aaagatgacg gcttcttgat tattgtagaa
      121 gcagtcgatg aatctccaga aattttaata tctcaagtat ttatgatgtc agaaccagat
      181 gatgttcgta tgaaaaaaaa tatcactttt ttgaaaatgg agcaatggat ggaaatattt
      241 aaaaatcaaa ggtttgaatt aattctattt gagccaggat atgaaaatta tttagagaat
      301 ttcaatcaaa aattatttgt gttgaaaaaa aatagaggtg aaaatcatga aaatagagaa
      361 taaattaata gagttgtaca gaaaaggtct tgaagtattt attgagggag ataaattaaa
      421 atacaaatct acttgtggta tgccctcgga agaagatata gaatttttaa aaataaataa
      481 aacttctatt attgatatat tgaataaaaa tgatggtgct tctagatatt cactagatat
      541 tgatgaatta cctttaacag aaattcaaag tgcatattta ttaggtagaa gaaatcattt
      601 tgaacttggt ggtgttgcca gtcatgttta tatggaagta atattacctc tattggatat
      661 agatcgagct gaaaaggttt ggaatgatat aatactaaag cacgatgcat tacattcaat
      721 atttacatca aacaatactc agaaagtact gaaggaattt gcttactata aaatcgaatg
      781 caatgagggt gcagatataa aagaaaaaat tgcattaaca agggataaac ttaaggggaa
      841 aagttataat gcagatatat ggccactatt cgatataagt gtaagtcagt tagatgacaa
      901 tagtttattg catttatcat ttgatttttt gattttagat tgggcaagca tttggatttt
      961 attaaaggaa tttgaagagt gttattttga cggaaagacg attatggata attcttatga
     1021 tcttaaagaa ataagaacga gtcaacttaa actgaaacat agttctaagt atttatcgga
     1081 taaagatttc tgggaaagaa gaattccttt tttgcctgac gctccactat taccaattaa
     1141 aaataaaata gtcaaaaatg gttttgaaag aatacaactt agaatagatg aaaatacttg
     1201 gtcgaagata aaatctaata taagtgagat tggtgtcacg caaacatctt tcttggtgac
     1261 aatattagct cttgttctta atagatggag ttctaattct gaatttacca ttaatttaac
     1321 aactatgaat agaccaaagg agtatataaa gagcgatgtt gttaatgatt ttacatctac
     1381 agaactttta gagtttagaa tggaatctct gcaaccattc tatgttttat taaaacacat
     1441 acaacagcaa atgattgaag atttgcaaca tgaaacattt acaggagtgg aagttactcg
     1501 tgaagttagg aaaaatgtag aaaggagaga tgctatattt ccatttgttt tcacaagtgc
     1561 attaggaata aaagcttcag aatataaata tattagttta caaaaagaag gtttgagtga
     1621 aactcctcaa gtattaatgg attgtcaagt aatggaggta aatcatgaac taataattaa
     1681 ttttgactta agagcagatg ctttttcaaa agaattatca aattcaattg cagaagacta
     1741 ttctaatcta ttaaattgct tttttgattt agaatatttc aaaaaaacac tgacagaaat
     1801 gtacgatgaa aatgagatga atgacgtttt agctgataag agtgattttg atagagtgaa
     1861 atacagagtt atagaacact cgaaaaaatt ctataataaa aatgtatttg atgctggaga
     1921 agtgagaaaa attttagaag aaagaaattt attttcaaat cagacaatgt taaaaacctt
     1981 gattgaaatt aaaggtgata taatttataa agattttaat aatattccag gaaatgtagt
     2041 acttggtgag tatcattgga tattaaataa atgggaaaaa catttagaca aagctggatt
     2101 tattaaagat aatggggatt tttatgtagt ttctgaaaaa ggggacgagt tacttaagct
     2161 taactttgat atagaattac taaaaaatag ttgggattat agtataggta attcagaggt
     2221 tatagactat ataataaaaa catctgaaaa tgttataaat attttcagtg gaaagatcaa
     2281 accaatatca atactttttc ctgaagggag ttctaagata gtagaatcaa tatatggtaa
     2341 taatattttt tgcaactatt acaataatat cataagaaaa gctattgaag aaataataga
     2401 tttagattct cataaaaata taaatattct tgagctagga gcgggtacag gaaacacaac
     2461 aaaagagatt ttaaaaatgc ttgaaatgaa aaatttagat tatagatata ttttcacaga
     2521 tagagcaaaa tcatttttag caaatgctcg aaataagttt ggtaactata aaaacgttga
     2581 gtataaacaa gttgatattg ataataactt gatggaacaa agttttttta atgatgaaat
     2641 aaatattgtt ttagcagttg gagtattaga gaatgcaaaa aaaataaaat atacgatttc
     2701 tagtatagag gaagtattga agaaggattc atgggtaatc atattagagc cagttgtgga
     2761 tgagccatgg atattgatga cacaactatt t
//
LOCUS       DARYLJ010000091         2707 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYLJ010000091 DARYLJ010000000
VERSION     DARYLJ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2707
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            116..703
                     /locus_tag="TU746_001911"
     CDS             116..703
                     /locus_tag="TU746_001911"
                     /inference="COORDINATES: protein motif:HMM:TIGR02185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL0892209.1"
                     /translation="MSNKLKGKDLITIGIYTAIYFVINFAFMLAGMIPVMWIMMPSLI
                     ALFTGVPYMMICNKVQKAGAILIMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRA
                     ITRYTSFIGNTLSFALFSIGMIGSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSP
                     AILIGVIILTFICSLVGALIAKRMMNKHFKKAGII"
     gene            705..1376
                     /locus_tag="TU746_001912"
     CDS             705..1376
                     /locus_tag="TU746_001912"
                     /inference="COORDINATES: protein motif:HMM:NF014420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0892210.1"
                     /translation="MREYRLKIDPRAGISLLFILNFTIFNVSTVYALFVLLIWNCVYA
                     MCNGYCRIAIKFIFTYWLLYLIEFLVLPKLPSLIAISFAILLTYILKMLPVALFGYVF
                     VKTTSLYELITALRKIHFPESIITGLSITLRYFPALREDFHKTYDAMKLKNMSVLEKI
                     SGLIITTMTRATLNIEELSQAASVRGIDNPVKKFSAAEINFKTSDAVVFIVSSVVYIF
                     ICVRY"
     gene            1390..>2707
                     /locus_tag="TU746_001913"
     CDS             1390..>2707
                     /locus_tag="TU746_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892211.1"
                     /translation="MVELKNISYSYSKENQILQDINIKIQDGECILLCGRSGCGKTTI
                     GRIINNLIPRFFERGVMSGDVYINNENTKDFEMHELANLIGTVFQNPKAQFFHTNSDA
                     EIVFGLENNGMKPEKIRRRYKEVVDELNIHDLTNRDMFSISGGQKQIIAFASIYAMNP
                     KVYVLDEPTANIDKKTIIKIGKIIEKLKKRGHTVIICEHRLYFLKDLVDRVFYVDQGE
                     IKRTFSGDEFFRLENKERISMGLRTLEVPKLKNMLTYDEICDNTLKIKNLSCCYGEKI
                     VFKNLNLSIRSGEILGIIGNNGVGKTTLLRCIAGLHKETKGEITLNGDVISGKKRQRL
                     SAMVMQDVNYQLFADSLVEECCLGNNCDNIQIDKVLGELKLIESKKSHPMILSGGQKQ
                     RLVVANAILSDKKILIFDEPTSGLDYEGMLAVSNELKKLSEKNYYIF"
BASE COUNT         1008 a          276 c          504 g          919 t
ORIGIN      
        1 aatgtattaa aacaatggaa agatatatgc tttggcattt ttacaagtca taaagtaaaa
       61 aaagaattaa ttaaagaatt tttattaaaa actacgatga cagaggagaa taataatgag
      121 caataagtta aaaggaaaag atttaataac aataggcatt tatacagcaa tttattttgt
      181 aataaatttt gcatttatgc tagctggaat gataccagtt atgtggatta tgatgccttc
      241 actgatagct ttatttacag gggtgccata catgatgatt tgcaacaaag ttcaaaaagc
      301 tggtgctatt ttaatcatgg gaacagttac agttttgata tattatgcaa caggacaatt
      361 tacaacagtt attcttgcaa cttttgcagt aggttgtata ttagctgaaa ttattagagc
      421 aattactaga tatacaagtt ttatagggaa tactttatca tttgcactat tttcaattgg
      481 aatgatagga tcgcctcttc ctatttggtt gtttaaagaa tcattttttg ctcatatatc
      541 agaggttggt atgtcgcagg attacataaa tgccttggaa aagtttactt cgccagcgat
      601 tttgatagga gttattattt tgacttttat ttgttcgtta gttggggctt tgattgcgaa
      661 aagaatgatg aataaacatt ttaaaaaagc gggaattata taaaatgcgt gaatatagat
      721 taaaaataga tccgagagca gggatttccc tgctttttat cttaaacttt acgatattta
      781 atgtatccac agtttatgca ttatttgtgc tattaatttg gaactgtgtt tatgcaatgt
      841 gtaatggata ttgtaggata gcaatcaaat tcatttttac ttattggttg ctttatttga
      901 tagaattttt ggttttaccg aaactaccaa gtttaattgc tatttccttt gctattctat
      961 taacttatat tttaaagatg ttaccagtag cattgtttgg atatgttttt gttaaaacta
     1021 caagtttgta tgagttaatt acggcactta gaaaaattca ttttccagaa agtataataa
     1081 cgggattatc aataactctt agatattttc cggcattaag agaagatttt cataaaacat
     1141 atgatgctat gaaactaaaa aatatgtctg ttttagaaaa aataagtgga ctgataatta
     1201 ctacaatgac aagagccaca ttaaatatag aagaattatc tcaggcagca agtgtaagag
     1261 gcatagataa tcctgtaaaa aaattttctg cggctgaaat aaattttaag acaagtgatg
     1321 cggtagtgtt tatagtgtct tctgttgtct atatttttat atgtgttagg tattgactgg
     1381 aggatagata tggttgaatt aaaaaatatt tcatattcat attcaaaaga aaatcaaata
     1441 ttacaagata taaatatcaa aatacaggat ggagaatgta ttttgttatg tggaagaagt
     1501 gggtgtggaa agacaacaat aggtaggatt ataaataatt taattcctcg tttttttgaa
     1561 agaggagtta tgtcaggtga tgtttatata aataatgaaa atactaaaga ttttgaaatg
     1621 cacgagctag ctaatttaat tggaaccgtt tttcaaaatc ctaaggcaca gttttttcat
     1681 acaaattcgg atgcagaaat tgtatttggt ttagaaaata acgggatgaa accggaaaaa
     1741 ataagaagaa gatataagga agttgtagat gaattaaata tccatgactt gacaaatagg
     1801 gatatgtttt cgatttcggg tggacaaaaa caaataattg catttgcttc tatttatgca
     1861 atgaatccta aggtgtatgt tttagatgaa ccaacagcaa atattgataa aaaaacaatt
     1921 ataaaaatag gaaaaatcat agaaaagcta aagaaaagag gacatacagt aattatatgt
     1981 gaacatagac tttatttttt aaaggatttg gttgatagag tattttatgt tgatcaagga
     2041 gaaattaaaa gaactttttc aggggatgag ttttttagat tagaaaataa agaaagaata
     2101 tctatgggtc ttagaacttt agaggtaccg aagttaaaaa atatgcttac ttatgatgaa
     2161 atatgtgata atacgttaaa aattaagaat ttgtcttgtt gttatggaga aaaaatagtt
     2221 tttaaaaatt taaatctaag cataagatct ggagaaatat taggaattat aggaaataac
     2281 ggtgttggaa agactacact tcttcgatgt attgcaggat tacataaaga aacaaaagga
     2341 gaaattacat taaatggtga tgttataagt ggcaaaaaaa gacaaaggct atctgcaatg
     2401 gttatgcaag atgtgaatta tcagttattt gcagatagct tagtagaaga atgttgctta
     2461 ggaaataact gtgataatat acaaattgat aaggttttgg gtgaactaaa attaattgag
     2521 tcaaaaaaat cacatcctat gatactttcc ggtggacaaa aacaaaggtt agtagttgca
     2581 aatgcgattt tatctgataa gaaaatatta atttttgatg aaccgacatc aggattggat
     2641 tatgaaggta tgcttgcagt gtctaatgaa ctaaagaagt tgagtgaaaa aaattactat
     2701 atttttg
//
LOCUS       DARYLJ010000092         2474 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYLJ010000092 DARYLJ010000000
VERSION     DARYLJ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2474
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            50..1003
                     /locus_tag="TU746_001914"
     CDS             50..1003
                     /locus_tag="TU746_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0892212.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1063..2262
                     /locus_tag="TU746_001915"
     CDS             1063..2262
                     /locus_tag="TU746_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL0892213.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          747 t
ORIGIN      
        1 ggctagtggt attcttttca tttcagcctt attttgatat gatagacgta tgaattttga
       61 aaagattgaa caagcctatg agcttatatt agaaaatagc cagctgattg aaaatgattt
      121 aaaaacgcat atctatgatg ctattgttga gcagaattct ttttatctgg gagcccaagg
      181 agcaagccct caggttgcta aaaatattga gacgttgaag gccttgcagt taaccaagga
      241 ggagtggcgc caggcttatc agtttgtttt gatcaaggct gggaaaacag agccattaca
      301 ggccaaccac caatttaccc cagacgcgat cggctttatc atgctttata ttttggagac
      361 cttgagctca caagagtcac ttgatgtgct tgagattggc agtggaacag gtaatttagc
      421 tcaaactatt ttaaaccact cacataagag cattgattat ttaggcattg agcttgatga
      481 tttactaatt gatctatcag ctagtatcgc tgaaatcatg gggtcatcag cccagtttat
      541 tcaagaggat gctatcagac ctcagctgtt aaaagaaagt gatctcatca ttagcgattt
      601 gccagttggt ttttatccta acgacgatat tgctagcagg tatcaggtgg ctagctcaga
      661 tgagcatacc tatgcccatc atttactgat ggagcaagcc ttaaagtacc tgaaaaaaga
      721 tggctttgct attttcttag caccggtaaa tcttttgagc agcccacaaa gtcacctctt
      781 aaaacaatgg ctgaagggct atgctcaggt tgtggccttg attactttgc ctgaggctgt
      841 gtttggaaat ccagctaatg caaaatcgat tattgttctt tgtaagcaat cgaatcgctt
      901 tgcagaaacc tttgtttacc ccattaggga tttgaaatct gttgataatg ttcgtgattt
      961 tatggaaaac ttcaaaaatt ggaaacggga taatgttatt taagagaatt ttttgatata
     1021 atagaaaagc attgcagaaa acgatttcaa gagaggtaaa acatgtcaaa gacaattgca
     1081 attaatgcag gaagctccag cttaaaatgg cagctatatc aaatgccaga ggaaaaggta
     1141 ttagcacagg gaattatcga acgtatcggt ctgacagact caatctctac tgttaaatac
     1201 gatggcaaaa aagaagagca tattcttgat attccagatc atacagaggc tgttaagcgc
     1261 ttgttgaatg atttgattca ttttggcatt attggtacgt atgacgagat cacaggtgtt
     1321 gggcaccgta ttgttgcagg tggtgaatac ttcaaggaat ctgtggttgt tgatgataag
     1381 gttgttgagc aggttgagga gttagcagcc ttggcaccct tgcacaatcc gggggcagca
     1441 gcaggtattc gtgcctttcg taagattttg ccggacatta cgagtgtttg tgtgtttgat
     1501 acttcgtttc ataccacaat gcaaaagcat acctaccttt atccaattcc tcaaaaatat
     1561 tatacagatt ataaggttcg caagtacggg gcgcatggga ctagccataa atatgttgct
     1621 gaggaagcag caaaaatgct gggtcgccct ctagacgaat taaagctcat tacagcccat
     1681 gttggtaatg gtgtgtctat cacagccaat tatcatggtc agtcagtgga tacctctatg
     1741 ggctttacac cgcttgctgg tccgatgatg gggacacgct ctggtgatat tgatcctgct
     1801 attattcctt atttgattgc tcaggatcct gagctaaagg acgcagcaga tgtggtcaat
     1861 atgcttaaca agcaatctgg attaggtggt gtgtctggta tttccagtga tatgcgtgat
     1921 attgaggctg gcttgcaggc taacaatcca gatgccgtct tagcttacaa tatctttatc
     1981 gatcgtatca agaaatttat cggacaatac tttgcggtat taaatggtgc agatgccttg
     2041 gtctttaccg caggtatggg tgagaatgct cccttgatgc gccaagatgt cgtcaatggc
     2101 ttgtcatggt ttggtatgga aattgatcca gagaaaaatg tgtttggtta tcgtggtgat
     2161 atttcaacag cagcttcaaa ggtgaaggtg cttgtcatct caactgatga agagctgtgt
     2221 attgcgcgtg acgttgaacg cttgaaacag actatatcat aatctgataa tatactctta
     2281 gctcagctga tcagttttaa agagtccaaa aaatactttt aattggtacc gacctccaaa
     2341 agttagactt aaaggtttaa cgattggagg tcggtattat tatatagcca aatattctca
     2401 agacaaagac agccaaaaaa tgagacggtc gtaaccgtct caaaaaagtt taatttaatt
     2461 aaaaacattc attt
//
LOCUS       DARYLJ010000093         2413 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYLJ010000093 DARYLJ010000000
VERSION     DARYLJ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2413
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..1035)
                     /locus_tag="TU746_001916"
     CDS             complement(<1..1035)
                     /locus_tag="TU746_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL0892214.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
     gene            1352..1879
                     /locus_tag="TU746_001917"
     CDS             1352..1879
                     /locus_tag="TU746_001917"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL0892215.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
     gene            1876..2268
                     /locus_tag="TU746_001918"
                     /pseudo
     CDS             1876..2268
                     /locus_tag="TU746_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
BASE COUNT          624 a          483 c          541 g          765 t
ORIGIN      
        1 ccctaacttc cgttcacgga tataagattt cttagcgaag gtaagttctg ggttaaattg
       61 ccaatccgat gaatcaagga tgtgttcttg aatatctttt ggagctcctc ggcgtccgcg
      121 atgtttctgt gagaagagcc agccatcttc ttgcttgagc atttctgaaa cattagccat
      181 actattcatc gccttatcgg cgactacaat taaccgctca attccaaatt gttttttgac
      241 ttcctcaacc gctggaagat aggtaacagg atcggtttga ttacctcgaa acagtttata
      301 gctaatcgga ataccgttgg tatccctaaa gagtcctaat tgcacaatgg gttttggacg
      361 gtgttcctta ctcggaccac gtcttcgaag cccttcttgt agtatctctc cattttctga
      421 aaccaactcg ttatctggaa tatctgtctc aaaataataa ttggtgacat cgtagaaaac
      481 gagactggct tcacgtttga tcatctgact cactaccttg tgaagatgat gttgaagatc
      541 atctttcaag gtgttcaatt tgttcaagga gcgataaatg gcatttaagc tgatgtccca
      601 atggccaaat aagtctgctt gagaggcata ggtggcaagt ttactatctg gtcggagaat
      661 tctctgaaaa actaatagct ttagcacttg cactaagtca tactcagact tcgttttgat
      721 accctttaaa aaggctgtga gccccagaga ttcgaagaga ttatccaaaa ccatccaacc
      781 ataagattga tccggttggt tcatgggggc aaggaggtca taggaaacct ggagtacctt
      841 agggttattt aaagtatctt ctttagcttc gcgcttaaga cgctcaagaa tccctggttc
      901 ttccaattca agctcatcta agagaccaaa ttttttaagg atacgctgtt tgaccttacc
      961 atctttacga tacccttcta caaggtagac atgcgtccta ccttctttat tcgttgttgt
     1021 tttaataaaa gccatagttt attataacat atataaccat acacaacaag aaaaagcgtt
     1081 aaaatttatt aaaaaaacct tactctacca aggggttgag taaggtgtgg actaaaacaa
     1141 gtgataaagt cgggtgtata gcataaagct taaacttttc ttaacctaga aaaataattt
     1201 tttgatctca tgagaccaca agctcacctc aagaagtaag aaggacattc actgattgag
     1261 ctgctgccct gtctggtagg acaactaagg aaagaacctt gattgtggcc gattcttgaa
     1321 tagtagcagc gctttgtgtt atgatatggg catgattaaa aaagattatc gccaactagt
     1381 gcttcagcgc ctagccatga tgaccccaga ggataagctg gaaaaggact tagctctatt
     1441 ggcagcagta gttgctagta gcagctatca agaggcgcag actcttgtga cctatctgcc
     1501 cttgccacac gagtatcaaa gccatctact gattgagcga gccttgcagg acggcaagac
     1561 tatccttgtg cccaagactc gttctcgtgg agagatggtg tttgtggctt atgatccttg
     1621 tgacttgata cagacggctt ttggtcttat ggagcctagg tgtaccatag ctgttgctaa
     1681 gtcggagatt gatgccattc atgtgccagg gcttgttttt caccctgcag gctatcgtat
     1741 aggctatggt ggtggctact atgatcgtta tttgagggat tatcaggggg ctacctttag
     1801 cacgatttat gcctgtcagt gggaggattt tgtggtagag gcacatgata ttgctgtgaa
     1861 ggaggtgtat tgccaatgag actgatgatc aaaaaatacc cgataacact ctttttcttg
     1921 ggcttgactg gtttagtttt tttgataatg cagctggtct atggccagtt tgctacgcac
     1981 ccttatgctg ttgttatatt tggtggcatg aatggtcttg ttgtcagagc aatgcctgat
     2041 cagctttggc gcttggtgac acctatagtg gttcatattg gctttgagca ttttttcatt
     2101 aataccttaa ccctttattt tgtcgggcgg atggctgaga ccatttgggg gtcaagacag
     2161 tttttgctgc tgtatgtgtg ttcagggatt atggggaatg cttttatcat gtggctgaca
     2221 ccagataccg tagcagcagg tgcttccacc tctctttttg gtctttttcc ttcaagctta
     2281 taagtgctag gacaggtgta tctttgattt aaacaaaaag caacggtttt gctgctgttg
     2341 ctttttaatg cttctaggac ggttgcccca actcctattt tgtctgctgt tgagtgcttt
     2401 ctagtgcttt acc
//
LOCUS       DARYLJ010000094         2359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYLJ010000094 DARYLJ010000000
VERSION     DARYLJ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..860)
                     /locus_tag="TU746_001919"
     CDS             complement(<1..860)
                     /locus_tag="TU746_001919"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892216.1"
                     /translation="MSVQVALKKALKPTWKRKLRQSWSIQRSTHLFSWYMVKHMDLTS
                     FRYVETNDYVLPEYGFKIHISGTFQNYKAIFSVVFPYLKCHHISFKYLKDEKMILENV
                     SDMEDPSESGKFITIYPRDREHCKQLLSDLYELIPVETEGVYILSDRNYKDSNVIFYR
                     YGLIEPREKVFVNAVPILIGPNGEQWQDFQKCYFDLPHWIEDLQEKQILLSSYLSENY
                     QVESLLKQSNGGNIYKAIHLDTGKNVVIKECRSHIICTASISKKQLRDNEWNLSGLIT
                     NNIPKSIEKV"
     gene            complement(1276..2142)
                     /locus_tag="TU746_001920"
     CDS             complement(1276..2142)
                     /locus_tag="TU746_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL0892217.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          744 a          448 c          318 g          849 t
ORIGIN      
        1 tgaacttttt caatactttt tgggatatta ttagttatta gaccagatag attccattcg
       61 ttatctctca actgtttttt actaatacta gctgtacaga taatatgaga gcgacattct
      121 ttgataacta cattttttcc agtatctaga tgaatagctt tataaatatt tccaccatta
      181 gattgcttta gtaagctttc cacttgataa ttttcactta aatatgacga caataaaatc
      241 tgtttttctt gtaaatcttc aatccaatga ggtaaatcaa aataacactt ctggaaatcc
      301 tgccattgct ctccgtttgg tccaattaat attggaactg catttacaaa aactttttct
      361 ctaggttcaa taagtccata cctataaaaa ataacatttg aatctttata gtttctatca
      421 ctaagtatat agactccttc tgtctcaaca ggtatcaatt catacaagtc acttaataat
      481 tgtttacagt gttctctatc tctgggataa attgtgatga atttcccaga ttccgaagga
      541 tcttccatat cggatacatt ttctaaaatc attttttcgt cttttaaata tttaaaagaa
      601 atatgatgac attttaaata cggaaatact acagaaaaaa ttgctttata gttttgaaat
      661 gttcctgaaa tatgaatttt aaatccatat tcaggtaaaa cataatcatt cgtctctaca
      721 tatctaaagc ttgtcagatc catatgcttc accatgtacc agctgaataa atgggtactt
      781 ctctggatgc tccatgattg tcttaacttt cttttccacg taggcttcaa agcttttttc
      841 aaagctactt gaacactcac gagaatcttc tttatagata catttttaag taatcattgg
      901 ttttctcata gcaatacatc tcctcagtct tattagtata aaactaaaaa cgctcacatt
      961 aacaggtctt tttgagcgtt tttagtagga ctagttacta aattatggtt tgtagattgg
     1021 acatttccaa gtcacaacaa agcctttcac tggcgcaaag catctactag cctcgtatgc
     1081 aaattgagtc atgtttgtga tctcctttca ttcttgatga gtctagtgta tcatcaaaaa
     1141 ccgtaccaaa gctaaactgt tcatatgttc aaatcatggt tttgacatta atcaaaaaac
     1201 agtagctcaa aaagccactg tttgctacta gctaagcatc taaaccattt tgcttatcaa
     1261 tgctttaagt tgcatttatt caacttcctt taaccatttc tctaaactat ctgaataata
     1321 ggctgcactt tcatcacaat ttaatgcctt taagatgtgt atggcgtcat ttatttgctt
     1381 taagcctagt tccttttccc ctttacaata taggtgctga ccatcagcaa tcatataaac
     1441 aattcttaag taggtgtcat tttcttcaaa aaaatgattg ttaatcattt tatcaaaata
     1501 tgcagctata cctagccttt tttcctgagt agctttaaac agcccattta ataaaatgct
     1561 gtgcactaaa tttcgatgct gccaaagctc ctcaaaaaag tctactcttc ctagcatttc
     1621 tcgagtatac cgcaaataca catccaagga taataaggga gaaatatctg aaaataattg
     1681 taattcgtat attccccaaa tctccactga aaacaaataa tcatataaaa agctttgctc
     1741 atctggagtc attttgatat tctcgtctaa aaagagcatt tggcttttaa tcatcaaagc
     1801 atttaaaaaa tagatatcct ttttgtataa atgatactgc tccagctctt ttgtatacaa
     1861 ttgatgtaag ctggacaggt ctttttttga tatggcctcc cagatctctt gctttaggac
     1921 agcatatggg gaaggcttaa agccatttgc tagatagata aattcattga gctctgtccg
     1981 aatattgcta agtccaacca atagctttga gattgttata tcggattcac cattttcaaa
     2041 tctgcttaac atcgagtgag aaaagtcatc tcccgtcgct tcctttaacg atatgtgtcg
     2101 cgatgtccgc agtaatttaa acatttctcc catatattgc atatcaatac ctcttcaatc
     2161 tttcatttta gtatagtata taaccttaaa aatgtaaatc cagtcttgat tgcataaacc
     2221 tttaattcaa cgtttgatgc tactaaatat cctatttttc tgaagtagat cctcatcttt
     2281 atgctataag cacttgctgc gttttagaaa atgggctaaa tcagctatac tcctttttaa
     2341 taacaaaaaa gccttattt
//
LOCUS       DARYLJ010000095         2260 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYLJ010000095 DARYLJ010000000
VERSION     DARYLJ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2260
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(227..721)
                     /locus_tag="TU746_001921"
                     /pseudo
     CDS             complement(227..721)
                     /locus_tag="TU746_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(947..1019)
                     /locus_tag="TU746_001922"
     tRNA            complement(947..1019)
                     /locus_tag="TU746_001922"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(984..986),aa:Lys,seq:ctt)
     gene            complement(1021..1214)
                     /gene="ssrS"
                     /locus_tag="TU746_001923"
     ncRNA           complement(1021..1214)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TU746_001923"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            1447..2260
                     /locus_tag="TU746_001924"
                     /pseudo
     CDS             1447..2260
                     /locus_tag="TU746_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          730 a          390 c          435 g          705 t
ORIGIN      
        1 aggttgtgac aatcgagcgg atatccgatg ttatggcaga actttctgag tctgaataat
       61 tttagttcac caaagaatca agaaagaacc attggggcaa aattggggca taagtttaga
      121 acttttgtcg tttcttgtgt cgatacaata ccggtttaat actaacaaat gcttttatta
      181 tcgactttgt aaccattatt gttccttgtg ttttttcggg aataaactca agaagttttt
      241 gagttttttc ttgaatttct ttttcatatt tcaatatgat gagtgaaatt ttatcttctt
      301 tggacatagt gttgttgtct tcaagattaa gttctttagt tgttagagtg tttttatcta
      361 atttattttg aaatattgca aaatctagaa ttttttgaag taatacttct tcctcggcca
      421 tacggctata aagccaatta ttttcgagtc tctctaggtg ctccatccac ttaaagtctc
      481 ttttttctcc taacatattg tagggaaata aggtatcaat atcaacattt aaggctgtag
      541 caatctcttg aagcctatcc catgaaggtt cagtagtccc cttttcgtca ttaataattg
      601 tttgcttagt aactcctatt aatttagcga gttctttttg tgtttttcca gcttttaagc
      661 gagcattttt aatatctatt tgtccaactg ttaaagcctg cgaataatta aaaaaagcca
      721 tttttctcca aattccgtcg caggtgatgg aggtgaaaat actccgattg tatcaccttg
      781 tgttaattat attattgtca tgtgttagct ctctttttaa aaagtaataa attctttatt
      841 taacatcata tcataaaaaa ttgtttcggg gacaaatggt gggacaaacc ctctttaggc
      901 aagcaaaaaa gccctgcaat aaaggctttt tgtcgttttt acactatacc ccctacaggg
      961 ctcgaacctg tgacccatag attaagagtc tactgctcta ccaactgagc taaggaggta
     1021 aggaaagctg tattggcacc ggtgattcac gttttgtatt gaacccgcac gatataagca
     1081 ggtgggcaac atacttctct tcagattgct tccacgtgaa acggcttgca tactagagat
     1141 agactttgtt tccctaaaat acaaaaaaat agtcggtcaa cacttagatg tgaattcgta
     1201 tgccacagca ataactctat gctcttatga taccactttt tgaaaatttt tcaagcccta
     1261 aaatgaaaaa aagatcgtat tttgacccgc accccaaaag ttagacagaa aatctaccaa
     1321 tggggtgctt tttatatgaa attaagttac gatgataaat taagaatata tgaactaaga
     1381 aaaaatggga tgtcttgttc ccgcattggt caacagtatg atattcaggt ttctaatctc
     1441 aaatacatgg taaagcttat ggacagatat ggagttgaga ttgttagaaa gggtaaaaat
     1501 aagtattatc ctccagaatt aaaacaagaa ataattgata aagttcttct tgaaggtcag
     1561 tctcaactgt ctgtctctct tgagtatgct ctcccaaatg ctggtatgct tcccaattgg
     1621 atagcgcaat acaagaaaaa cgggtatact attcttgaga aacaaagagg gagaccaacg
     1681 aagatgggcc gtaaaccaaa gaaaacttgg gaagaaatga cagagctaga gcgccttcag
     1741 gaagagctag aataccttag aacggagaat gcttatctaa aaaagttgag ggagcttcgt
     1801 ttacaggacg aagccagaga atgagaaagg cagaaacaat tagagagatg gtccaagaag
     1861 gattccgatt aaacctccta cttgagatcg ctaagatggc tcgttcaacc tattattatc
     1921 aagtcaagca attggataag tcagataaag atgaagcaat caactctgaa atcaaagcga
     1981 tttatgagga gcataaggga aactatggtt accgtcgcat tcatttagaa ctcaagaatc
     2041 gtgggtttat cgtcaatcac aagaaagtgc aacgcttgat gaaagagatg agattagctg
     2101 ctcgaattcg tcgtaaacgc aggtattcct cttacaaagg cgagactggt aagaaggctg
     2161 ataatctgat tcaacgccag tttgaagctg ctaagccata tgaaaaatgt tataccgatg
     2221 tgacagagtt tgctttacca aacaacgatg aaaaacttta
//
LOCUS       DARYLJ010000096         2226 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYLJ010000096 DARYLJ010000000
VERSION     DARYLJ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2226
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            82..438
                     /locus_tag="TU746_001925"
     CDS             82..438
                     /locus_tag="TU746_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892218.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
     gene            962..2011
                     /locus_tag="TU746_001926"
     CDS             962..2011
                     /locus_tag="TU746_001926"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL0892219.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
BASE COUNT          733 a          443 c          395 g          655 t
ORIGIN      
        1 ttttgacaga ttttgagtta aactaacatt gtgataagga aaatatcaca aaaataacga
       61 cggacaaagg aaccgttgga aatggaggac acttatatga cacaagcttg taagaaattt
      121 atggtttcta caatggctgc cctagctttg gcaggagtct gcctaacagc ttcaacccac
      181 atcagcaaag ctgatgacta tgtttatggt gacgtggaat atcttttgac gcctaagcaa
      241 gaaggatacg atgatttggt gtcattcttg gagagtctag gccttaacca ttttgatgcc
      301 actctttatt cggactctat ggctgatcaa gattacaaaa agctactagc tgactttaag
      361 ggtaaaactc gtagtgaagt tatttctgca gttctatctg aattagctaa attttataac
      421 gactattccc ctttttaatg aaataaccca ataagttatc atagatcaaa actgctcaga
      481 caaccttccg agcggtttta acttgataga gctatgcttc tctttgtcaa tctgcttagt
      541 aaccagacca tctcctaaat cgtccgccta gctaatcaag taataactgc accattgtcc
      601 ttactatcct agctaatgcc ctgatttgct gactaagctt ggctaagatt gtgcaagaat
      661 cccaataaca tcaaagccta cactagctct tattagtggt ctcaataata acagctcatg
      721 tctaaggcat gacaccaaca ataccaaacg gtatcatcat tggtaaaata ggtaacgcta
      781 acataaacca agctgaaata tccattatag agatccagtc tgccagcatc tctactatct
      841 catcactatt tactaataaa taaagcttat caaaagcatt gtctcaacaa aatattgtga
      901 taatatataa atgtcattaa cattatttaa tgataatatc accataacaa gaaagggtta
      961 tatgaaaaca atagcttatc caaataaacc tcactcctta tcagctggtc tcttaactgc
     1021 tatagctatt tttagcctgg cgagttcaaa cattacttat gctgacgatt accaaaggaa
     1081 tgctacggaa gcttatgcca aagaagtacc acatcagatc acttctgtat ggaccaaagg
     1141 tgttacacca ctaacacccg agcagtttcg atataataac gaagatgtga tccatgcgcc
     1201 atatcttgct catcaaggct ggtacgatat caccaaggcc ttcgatggga aggataatct
     1261 cttgtgtggc gcagcaacgg caggtaatat gctgcattgg tggtttgatc aaaataaaac
     1321 agagattgaa gcctatttaa gtaaacaccc tgaaaagcaa aaaatcattt ttaacaacca
     1381 agagctattt gatttgaaag ctgctatcga taccaaggac agtcaaacca atagtcagct
     1441 ttttaattat tttagagata aagcctttcc aaatctatca gcacgtcaac tcggggttat
     1501 gcctgatctt gttctagaca tgtttatcaa tggttactac ttaaatgtgt ttaaaacaca
     1561 gtctactgat gtcaatcgac cttatcagga caaggacaaa cgaggtggta ttttcgatgc
     1621 tgttttcacc agaggagatc agacaacgct cttgacagct cgtcatgatt taaaaaataa
     1681 aggactaaat gacatcagca ccattatcaa gcaagaactg actgaaggaa gagcccttgc
     1741 tttatcacat acctacgcca atgttagcat tagccatgtg attaacttgt ggggagctga
     1801 ttttaatgct gaaggaaacc ttgaggccat ctatgtcaca gactcagatg ctaatgcgtc
     1861 tattggtatg aaaaaatatt ttgtcggcat taatgctcat agacatgtcg ccatttctgc
     1921 caagaaaata gaaggagaaa acattggcgc tcaagtatta ggcttattta cgctttccag
     1981 tggcaaggac atatggcaga aactgagcta accagtcatc attaggaaca gaccaagtgc
     2041 ttattggtct gttttttcgt ctaacaatag ccctattagc tcactgtcat tggttaaagc
     2101 ttgtcatgaa ctctttaagc tcttgttttg ttaaacatta atgtgcctgt tgttcttttc
     2161 taagataagt aaactagata cctgacataa aaaacaaacg ttattattta tcttaataaa
     2221 aaaatc
//
LOCUS       DARYLJ010000097         2216 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYLJ010000097 DARYLJ010000000
VERSION     DARYLJ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TU746_001927"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TU746_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL0892220.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TU746_001928"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TU746_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL0892221.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGDFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          556 c          389 g          645 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagt caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagct
//
LOCUS       DARYLJ010000098         2059 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYLJ010000098 DARYLJ010000000
VERSION     DARYLJ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2059
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            54..455
                     /locus_tag="TU746_001929"
     CDS             54..455
                     /locus_tag="TU746_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL0892222.1"
                     /translation="MAVKRKYIYVKGQKIYVPDEVYRAYKKGLNHETHLKRLDRKHGV
                     FRFGDFNTSIVDIADNTVDVEKIIETKMLIEDLYYALDSLNDEERKLIEALYFDDKTL
                     TEVAKQRDTNPMKISRLRNKILEKLRKFLDK"
     gene            911..1078
                     /locus_tag="TU746_001930"
     CDS             911..1078
                     /locus_tag="TU746_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL0892223.1"
                     /translation="MCEEHNIDIKMEIDKKDKQTINQIDGWNIEVKFNENGLSLENLV
                     EEYIKEKFSVY"
     gene            1177..>2059
                     /locus_tag="TU746_001931"
     CDS             1177..>2059
                     /locus_tag="TU746_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019115678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0892224.1"
                     /translation="MFKDSVNKENIAVMYLRLSKEDGEKTESNSISNQREMINSYAKK
                     NQFIIIKEYVDDGYSGATFDRPNFKEMINDAYDKKFDTIIVKDLSRFGRDYIEAGKYI
                     QRIFPENGIRFISVNDNYDSKSADMNDTHLILPIKNFINDSYCRDISNKVKSSQKIKR
                     EKGDFISAFAPYGYKKSDENKNKLVVDEQAAPNIKNIFDMKLLGYSSKAIADELNHLG
                     VLTPRKYKESQGFKCNGFQNIKGGNWSAKSVNRIIENEVYIGNTLQGKSVTLNYKNKK
                     QIEREKEDWIRVENTHDA"
BASE COUNT          846 a          221 c          398 g          594 t
ORIGIN      
        1 tttttattca aaaaataagt ttgaaatttt tgataaaaag gagggcttta caaatggcag
       61 ttaaaagaaa atatatctat gtaaaaggtc aaaagattta tgtacctgac gaagtgtata
      121 gagcatataa aaaagggctt aatcatgaaa ctcatttaaa gagattggat agaaagcatg
      181 gcgtatttcg ttttggagac tttaacacaa gtattgtaga tattgcagat aatactgttg
      241 atgttgaaaa aatcattgaa acaaaaatgc tgatagaaga tctgtattat gcattagaca
      301 gtttaaatga tgaagagaga aaactaattg aagcactata ttttgatgat aaaactctca
      361 cagaagttgc aaaacaaaga gacacaaatc caatgaaaat cagtagatta agaaataaga
      421 ttttagaaaa gctgagaaaa tttttggata agtaaattaa gtagagggca gggaaacatc
      481 tctgtcctct atttttgaaa atttttcaaa aatagtgtta aaagttgtcc tgaaagtaag
      541 gtttatatat agagggactt ttattacctc gttatatata gatttgatct ttgacaactg
      601 aatagaccaa gacaagactt taaccagtag tggagcaatt tataaactta cgccaagata
      661 aacctgctaa gttaaattga tttaaatgaa tacctacatt tgtagaggat ataaggtttg
      721 gagcgataaa taagtctgta taaaaagagg gtggcaactc ttgtgcgatg atactaatgg
      781 ggataatgat acttctacag ttgaagccgg ctcatcttga aaagaggcgg aggtgaaatt
      841 cctatgtagc agccaatgca cttgtcaatg tcataaaact taaaaatatt gaagataagg
      901 agaagatatt atgtgtgaag aacataatat agatattaag atggaaatag ataaaaaaga
      961 taaacagaca ataaatcaaa ttgatggttg gaatatcgaa gttaaattta atgaaaatgg
     1021 attgagctta gaaaatttag tagaggaata catcaaagaa aaattttctg tctattaggg
     1081 gctgacaaaa aatataagga gcgttataat atttttgtgg aagcctaacc ttggttcgat
     1141 ttattgtatg taaattgaat ttaaggaggc ttttttatgt ttaaagacag tgtaaataaa
     1201 gaaaatattg cagttatgta tttgaggctt tcaaaagaag atggagaaaa aacagaaagt
     1261 aattctatat ccaaccaaag agagatgata aattcttacg caaagaaaaa tcaatttata
     1321 attatcaaag agtatgttga tgacggatat tcaggagcaa cttttgatcg tcctaatttt
     1381 aaagaaatga taaatgatgc ttatgataag aaatttgata cgattattgt aaaagaccta
     1441 tcaagatttg gaagagatta tatagaagca gggaaatata tacaaagaat atttccggaa
     1501 aacgggataa gatttatatc tgtaaatgac aactatgata gtaaaagtgc ggatatgaat
     1561 gatacacatc taatactccc tataaaaaac tttatcaacg acagctattg ccgagatatt
     1621 tccaataaag taaagagttc tcagaagata aaaagagaaa aaggggattt tatcagtgct
     1681 tttgcacctt atggatataa aaaatctgat gagaataaaa ataagttggt ggttgatgaa
     1741 caagctgctc ctaacatcaa aaatatattt gatatgaagc tcttgggata ttcctcaaag
     1801 gcaatcgcag atgaattaaa tcacttaggt gttttgactc cgaggaaata taaagaaagt
     1861 caaggcttta agtgtaatgg atttcaaaat ataaaaggtg gtaattggtc agcaaagtca
     1921 gtaaacagaa ttatagaaaa tgaagtatat attgggaaca ccttgcaagg caaaagtgtt
     1981 accttaaact ataaaaataa aaaacagata gaaagagaga aagaagattg gataagagta
     2041 gaaaatactc atgatgcaa
//
LOCUS       DARYLJ010000099         2012 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYLJ010000099 DARYLJ010000000
VERSION     DARYLJ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2012
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            1..881
                     /locus_tag="TU746_001932"
                     /pseudo
     CDS             1..881
                     /locus_tag="TU746_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            874..>2012
                     /locus_tag="TU746_001933"
     CDS             874..>2012
                     /locus_tag="TU746_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0892225.1"
                     /translation="MNKKIIFKGDQDSKFAYFSLMFSAGTAIENTEELGFSHLIEHLL
                     LRSGGEQSLNELFDNNGAFIGGETSRDYINLMGYCKAENFKNIFEAIVSRVFNLNLTE
                     EELLREKRVVLVELTQYENGSKTEKLVSDNRLIFKNSKWSEDIIGVRENIESVDLKKL
                     YKFYTENIQNGEFQIAISGPNHLKEEIAIIENKLPVGRTPVKSNFPIFSSGVTERKKN
                     QQVSEISMYIDISKMTTSSHDVAILTILNAMLTGVKGSVLGGKLRTKNQWVYNIISFP
                     IFYNGLTILKILTRTPEIHKHQVVQVLKEDLVNREDLKNTKLFDKAKKRVINEVLMSY
                     EVKKVEFLKTLCREKLFNIPSWESVTGEIEKVSLNELNQFAKDAL"
BASE COUNT          754 a          226 c          383 g          649 t
ORIGIN      
        1 tcgaaattta ttggaaatat tggataatcc aataaatcaa ttacaggatt ataaatcaat
       61 tgagtcgtta gaaacatatt atgctagtga aggaattggt gggattaaac tattaaaaat
      121 gttagggaat ctaaagattt ctattctggg atgtggtggt ggtggatctc atattgcatt
      181 acaattagct caattaggag tgggaagaat tcatttggtg gattacgata ttgttgaaga
      241 aaacaatatc aacagacaat ccatgttcac atttaacgat gtcggaaatt acaaagttga
      301 ttgtgtagcc aaaaatattc agcaaagaaa ttctaaatgt ttggttacca aaagcacttc
      361 taaaatgatt aatgtacctg atgtaaaaaa aagaaatatc tgaaagcgat tgggtattct
      421 gttgcatgga tgaacctcct tatatagcac agaggattgt aaatagagca tgttatttat
      481 taaaaattcc aagtatatac tgttttagcc aacgtagtgc ggggaaactt ttgttttgta
      541 atcctaatat tgaagattct ggctgtattg attgtttgtt atctgaacaa gataatgaaa
      601 actttcaaaa gctggtgaca acgttcacta cctataatag gaaattggta actgcaaata
      661 tcttaccaaa tattttatta ttgacatcgt gggtggttaa acgatggtta gattgtgtaa
      721 cagataaaaa tagtaatgta tggaatatgt tgttgagatt tgatttttat aaatatatgg
      781 aagaaaaatt tcaatatttt tcgaaacaag atagttgtcc aacatgtgct aagggtctta
      841 gtacaagtaa attatgggag attttaaaaa tagatgaata aaaaaattat ttttaaaggt
      901 gatcaagata gtaaatttgc ttatttttca ttgatgtttt ctgcaggtac tgccattgaa
      961 aatacagaag aacttggttt ttcacatttg atagagcatt tattattacg atcaggcgga
     1021 gaacaatcat taaatgaact atttgataat aatggtgcat ttattggagg tgaaacttct
     1081 agagattata ttaatttgat gggttactgt aaggctgaaa atttcaaaaa tatatttgaa
     1141 gcaatagtaa gtagggtatt taatttaaat cttactgaag aagaactgct aagagaaaaa
     1201 agggtagttt tagttgaact aacacagtac gagaatggga gcaaaacaga aaaattagtt
     1261 tcggataacc gcctaatttt taaaaatagt aagtggtcag aagatattat tggtgttagg
     1321 gagaatattg aatctgttga tttgaaaaag ctttataagt tttacactga gaatatccaa
     1381 aacggagaat ttcaaattgc tatttcagga ccgaatcact taaaagaaga aatagcgatt
     1441 attgaaaata aattaccagt tggaagaact cctgttaaat ctaattttcc tattttttct
     1501 agtggtgtaa cagaacgaaa gaaaaatcaa caggtttctg aaatttcaat gtatattgat
     1561 atttcaaaaa tgacaacatc atctcatgat gtagcgatat taacaatttt aaatgcgatg
     1621 ttaacaggag ttaagggttc agtgttagga ggtaaattaa ggacgaaaaa ccaatgggta
     1681 tataatataa tttcattccc aatcttttac aatgggctca ctatcctaaa gatactgact
     1741 agaacgcctg aaattcataa gcatcaagta gtacaagttc taaaagaaga cttagtaaat
     1801 agagaagact taaaaaatac gaaattattt gataaagcta aaaaaagagt tatcaatgaa
     1861 gttcttatga gctatgaagt gaagaaagtc gagtttttaa agacactttg cagggagaaa
     1921 ttatttaata tacctagttg ggagagtgtt actggggaaa ttgagaaagt ttctctcaat
     1981 gaacttaatc aatttgctaa agatgctctc at
//
LOCUS       DARYLJ010000100         1907 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYLJ010000100 DARYLJ010000000
VERSION     DARYLJ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1907
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(275..1789)
                     /locus_tag="TU746_001934"
     CDS             complement(275..1789)
                     /locus_tag="TU746_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0892226.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          656 a          387 c          315 g          549 t
ORIGIN      
        1 tcccttggga cacaaggggt tagctggtct ttacttgttt ttaagtgata aagtcgggat
       61 tataacaaaa atccacttga aaggcttatc acaagtggat ttttcagaaa tattgtacca
      121 aataggcacg agctattgat tgctgctatt tagcataggt gttatcacga tcagcagtaa
      181 gccaatcaaa acaggtatcg ctaaagcaaa tcctcacaaa aaatggtcca aagaaaaacc
      241 tagcagcctt ataccacttg cttagcaaaa aaacttactc taccctatct ccaatcaaga
      301 gctgctctaa aagctgctcg taatgcttac gatgaaagtt cagaattgat tttaccactg
      361 tttttccctg ctccttaatg taatccatgc tcataccaat taagacgctc ttatctggaa
      421 atacctgctg ctcctcaaga aaaggcaaaa tattatcact cgtaatcaca aaatcaggag
      481 cctgctcata attttccaga ctatctgtta gcatgttgat acgagtaata ttaaccttat
      541 aagaaggaat acttgagata acaaagtaag acaagacatc acctaatgct ctcttgtttt
      601 caacgatgat gacctctaca ggcggcaagg acagctcaag catctgctcc aaatgaaggc
      661 acataaaatg caggtgccct ggtgagagcg tttctgactg gtagctaacc atcagccagt
      721 ccttgatttg ctcctcaacc ttttctagca gcagctgact gccttgatac ctctttgaat
      781 agtaatcctg aaagctaatc aaatcatgca attgaaagag acatcttctg aaaaagggaa
      841 gcaaaaaata catctgatcc cttaaatgaa gctgacgacc aaacaacatt tccaagcgat
      901 taacaagctc cttatacagc ggatcttctt ctaagatatt gtagacaaga cgtaattgct
      961 tgtcattcca ataatgcata agaaaagaac tatcaactgt aagataaacc aagtaaagat
     1021 aatctaagtc accagaatta aacacaacct gagtacgtgt ctcaatttct tgcttagcat
     1081 agcaactgat ttgctcaaaa atagataatt cttttaaacg atcaaataaa gtaagctgtg
     1141 gtaaggatac atcataattc tgcctcttcc aagacagcat gagtaaaata tcaaaaagat
     1201 aaaatttctt gtccaagaaa acagtgggct ttaaccgcgt aggggttaaa aaaataaagg
     1261 catgaataat ttccatatcc ttaggtgtca tctcataaac agcaaaccca tactccttat
     1321 gaagcatggc aattaagtag cgaatccggt actcatcccc tataacccgg taatcatcga
     1381 tatccaaatg aatggattgc aggtagccct ttagcttatt gacaagatga taggcctttg
     1441 atttggaaat aaactgtctt ctgatgaaag ttgtcagaca ctttgtcctg taattatccg
     1501 tcaacagaaa cttcaacatt ttaagcgtat cagatgatgc ataaatactg tgaaaatact
     1561 tctccttgtt attaggatca aactcacagg taatgcctga cttcaataca gtaatagaca
     1621 ggtctttgtc aaatagtgca ttaatctgat taaggtattc cttagccttt cgaggggtta
     1681 ttgacgtctg cgagcacaat gaatcaagtg taatctcttt ttctgtcaat aagacagcca
     1741 atattagttt tcgctcaaca atatctcttt ctaaatagta atctaacaaa ataatctctc
     1801 tccttattag tttgtatgac catatacatt ttagttgata ggatttaaaa gtcaactaaa
     1861 aaaaatacac aaaaaataac gactgcttcc tttcaaggat catctga
//
LOCUS       DARYLJ010000101         1873 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYLJ010000101 DARYLJ010000000
VERSION     DARYLJ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1873
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..456
                     /locus_tag="TU746_001935"
     CDS             <1..456
                     /locus_tag="TU746_001935"
                     /inference="COORDINATES: protein motif:HMM:NF020376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892227.1"
                     /translation="KSNEVKLVREPNNKHDQNAVKILVKNIFIGYIPHEIAKEINRYL
                     KNKKYNYDASISIYGGPYKTIDMDLDIIEHQLNINCDIALCILSNTSKSKSKNITFTD
                     AIAAIMFLIGILFCLVAISFLLKGKFLEFLVGLFFTLVLSIPAYLKFSK"
     gene            634..1800
                     /locus_tag="TU746_001936"
     CDS             634..1800
                     /locus_tag="TU746_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL0892228.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWNMYVDNRLKTGSWKPDTEANKEAIYK
                     THFKKYLGKTKMKDISRIEYENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDD
                     NPIDGITIGDSEIIPVNKRISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVA
                     IKIGNLTKLENGRYRILLDESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVES
                     KRIAKKYNRILSKEDYLFLTNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
BASE COUNT          715 a          298 c          325 g          535 t
ORIGIN      
        1 aaatcaaatg aagttaaatt agtacgagag cctaataata aacatgatca gaatgctgtt
       61 aaaatattag ttaaaaacat ttttataggc tacattccgc atgaaatagc taaagaaata
      121 aatcgttatt taaaaaacaa aaagtataat tacgatgcat ctattagcat ttatggtgga
      181 ccatataaaa cgattgatat ggatttagat atcatcgaac atcaattaaa tattaactgt
      241 gatattgcac tctgtatttt gtcgaataca tcaaaaagca aatctaaaaa tattacattt
      301 acagatgcaa ttgcagcaat aatgttttta attggtatct tattctgctt agtagctata
      361 agttttttgc ttaagggtaa attcttagag ttcttagttg ggttgttttt tacattagtt
      421 ttatcaatac cagcatattt aaaatttagt aaataaaaca aaaaagcccc acgttacaac
      481 cgaccaaagc gcaacgtgga gactacacaa aatataaaac aaccattaaa aagggcgttt
      541 tattatacct aattatatca cacaaaggag gtgatgccaa tatcctttca aacgacctcg
      601 tccaaaagtc aaaatacatg aaaggatttt aaaatgaaat acaacaaaac aaaataccca
      661 aatatcttta cctacgatac aaagaaaggt aaacgctact acgtccgtag gggttattac
      721 ttaaaaggta aaaagaaaga ggctacaaaa agcaacttaa aaacgctaca ggaagccaga
      781 gctgcactta ctgaaattga gcaaaaaata gaaaacaatg attttgctta taacaaaaat
      841 ttgacagttg atcagtactg gaatatgtat gtagataatc gcctaaagac cggatcatgg
      901 aaacctgata ccgaagcaaa taaagaagct atatacaaaa ctcacttcaa aaaatattta
      961 ggcaagacta aaatgaaaga tatttctaga attgagtatg aaaatcatat taatggtatg
     1021 cgtaagaatt attcaaagaa cactttacgc ttgatccatt cagtactcaa cgcaatgctt
     1081 aatcatgcag tcaccaataa aatgctagat gacaatccaa ttgatgggat aactattggc
     1141 gatagtgaga ttatacccgt taacaaaaga atatcgcttg aagaattcaa agagtgggat
     1201 tcatgggcca agaagtcatt gattcaatac gattatacta ttgtccgtat gacttacttc
     1261 ggagctcgta gtagcgaagt tgttgccata aaaattggca atttaacaaa gcttgaaaat
     1321 ggtagatatc gaatattgct agatgagtct aggacgtacc atcgtccaaa cggtggagga
     1381 atgaaaacgc caggatcaga gcggtttatg gaagttgatc ttgaaacatc gcattatatt
     1441 gatgatgttg ttgttgagtc taaaaggatt gcaaagaagt ataatcgtat attatcaaaa
     1501 gaggattacc tatttttgac taactttaag aatgcgaaaa aagaactttt aggaatgccg
     1561 atctctatta ggcgagtcta taaacttttt aatactgtca atgaaaaatc tggtatgcat
     1621 gttaccccac acatgatgcg ccactttttc gccacccaag ggcagatagc aggtgtccca
     1681 attgaacata tggccgcagc actaggtcat tctacaagtt acatgactag caaatatact
     1741 cacataaagg aggaggttgc tggtagtgtt actgatagat ttatgagcgc tttaaactag
     1801 ttagtcgggg aaatttatac aaatgcttaa attaacaaat cccccgatat attccccgac
     1861 aatttataga ttt
//
LOCUS       DARYLJ010000102         1798 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYLJ010000102 DARYLJ010000000
VERSION     DARYLJ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1798
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..357)
                     /gene="spek"
                     /locus_tag="TU746_001937"
     CDS             complement(<1..357)
                     /gene="spek"
                     /locus_tag="TU746_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL0892229.1"
                     /translation="MKKNTLALLFLVCVSLTLCTTESVFSDTYNTNDVRNPRNIYAPR
                     YDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISS
                     NLSPSQERMFNVGDHVN"
     gene            complement(482..1711)
                     /locus_tag="TU746_001938"
     CDS             complement(482..1711)
                     /locus_tag="TU746_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0892230.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGETDYKKACHAIKAAGYATASDYAELLIQLIEQNDLQKWDAEALAKRKESQMISS
                     QCREVIEFYINLANAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASA
                     QGWEVHRMPTDANPRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNAD
                     ALYVGGPARFNTRDFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETSKSGTFTLDA
                     AEINVRRWPNLTSEVVDSYKQGQTVSFDSEGYANGYYWISYVGGSGKRNYMAIGPTDK
                     DGNIISLWGKLGGKDPR"
BASE COUNT          510 a          419 c          317 g          552 t
ORIGIN      
        1 attcacatga tcaccaacat taaacattct ttcctgtgaa ggagaaagat tactagatat
       61 gactttctta aaagtgttat cattccaaac tgtagtattt tcatccgtat taaaaatcaa
      121 ttgcgttcct tgtttggcat ttatcgatat attatttttt tcaataattt ctttattata
      181 tatttctttt aatcttctat tatctaaaat ttcgtcttta tcatatctag gagcatatat
      241 gttccttgga tttctaacat catttgtatt gtacgtatct gaaaagacac tctcagtagt
      301 gcatagggta agcgatacac acacaaggaa tagcaaagcc aaggtatttt ttttcatttt
      361 ttctcctaat attttttaaa tttaatcaat ttacttagca agtatactat atttaaataa
      421 taattcaact ataatttaaa aaaaacaaaa aaccgccctc aatcaagaga gcggttttgt
      481 cttatctcgg atctttacct cctaatttac cccaaagact gataatattc ccgtctttgt
      541 cagtaggacc aattgccata taattacgct tacctgagcc tccgacatag ctaatccagt
      601 agtagccatt ggcgtaaccc tcactatcaa agctaacggt ttggccttgc ttataactat
      661 ctactacctc actggttaaa ttcggccagc ggcggacgtt gatctctgcg gcgtcaagtg
      721 taaaagtacc tgattttgat gtctctacga tcgtgtctga ggtttgcggg tctgtgctga
      781 ccgtttgtgc agcaacatct ccctgataag gaggataaaa ccagccggcc acattagtaa
      841 agtcacgagt attaaaacgg gccggacccc ctacatacaa cgcatctgca ttaccatcaa
      901 tattttgctc gatagtctgc atagtgtaac catctgagtc aacgtacaca agacccgtat
      961 gaccataatt gataccacca aaccaagcgt ccatgacaaa aaatgcccca gctcgtggat
     1021 ttgcatctgt aggcatgcga tggacttccc agccctgcgc acttgcgcta tctagtaagt
     1081 ccgctgcgtt gccccagaga tcgacaccaa accagtgctt agctgcgtaa caagggacat
     1141 ctgcacattg cgtgccataa gccccgtcct tatcaacacc cataccagca ttagccaaat
     1201 tgatgtaaaa ctcgataacc tctcgacact gcgaactaat catttgtgac tcctttcttt
     1261 ttgctagggc ttccgcgtcc catttttgta ggtcgttttg ctctattagt tggataagca
     1321 gctctgcata atcacttgca gtggcataac cagctgcttt tattgcatga caagcctttt
     1381 tatagtcggt ctccccgata actgatttgt atcgtggatt atccactaaa aactggccat
     1441 gatcaaggat tgactcgtcc caactgtcat aggctctaaa gcggtccacg agatccgtca
     1501 cgacacctgg ctgatactcc tcttgtgtct tggtatcaaa agatttacca gaccatgagc
     1561 tatctgcctt gataccaaac aatgcgttat gtggggcata cttgccccaa ccgctctcta
     1621 aaatagcttg agcagccgtc agagatggca aaatcttatg attgtgccac tctgcgataa
     1681 ctgcgctttt tatgtcgtct aaaaaggtca tctgtcctcc tcacctaaaa acggataaaa
     1741 gataagagca atcacagata gcggtaaata tagtattgcg attgctagga ctattgct
//
LOCUS       DARYLJ010000103         1642 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYLJ010000103 DARYLJ010000000
VERSION     DARYLJ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            76..630
                     /locus_tag="TU746_001939"
     CDS             76..630
                     /locus_tag="TU746_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0892231.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            630..878
                     /locus_tag="TU746_001940"
     CDS             630..878
                     /locus_tag="TU746_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892232.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            902..1603
                     /locus_tag="TU746_001941"
     CDS             902..1603
                     /locus_tag="TU746_001941"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL0892233.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
BASE COUNT          474 a          311 c          421 g          436 t
ORIGIN      
        1 ggctatgcca agaggctgcc acatcaccca aatcaagcaa agtaaaatga tggagagaaa
       61 gcaaggagat cagacatgga ttttgaagaa aaaacgatta aaaggcaaga gatttttgat
      121 ggtcacattt tcaaagttgc ggtagatgat gtccaattgc caaacggcct aggtcaggct
      181 aagcgcgaat tgatttttca tcgcggtgca gtcgctatat tggctgtaac gccagagcgt
      241 aagctgttaa ttgtcaagca gtaccgtaag gctatcgaag cgatttctta tgaaattcct
      301 gctggaaaac tagaggtcgg tgaggccaac tcagcattag aagcagcagc acgagagctg
      361 gaggaagaaa ccgcctattc tggtgatttg cgtcttattc acgagtttta tacagcgatt
      421 ggtttttgta atgaaaaaat taagctgtac ttggcgacag acctgcagag agttgccaat
      481 cctagaccac aggacgcaga tgaggtgatt gagcttcttg agctgagcta tcaagaatgt
      541 atggatctag tggcacaagg aaagcttgtc gatgctaaaa ccatcattgc cctgcaatat
      601 tacgcccttc attttggagg tgatgtgtaa tgggcaagcc cttgctgact gatgacatta
      661 tcgaaaaggc tcagcgcgga gaacagtttg agcctgacga ttatgcagat tttgaaacca
      721 aaatcatgac ctttgaggat aagcatactg atcgtattta caaaagtcgc agaattgaaa
      781 atgcaaagcg cagtcgcttt caatcgcggt taaatctgat tctcttagcg gtgcttgtct
      841 tgattgctct cttggtttat gcggtcttta atttatagaa aaaaacaaat aaggatatca
      901 tatgaaaatt ggaattattg cggctatgga agaggagctg cggtttttat tggagcagct
      961 ccacgatagt caagagcatc aggtgctttc caatacctac tatacaggtc gtcttggtcg
     1021 ccatgagctc gtcttagtcc aatctggtgt tggaaaggtc atgtcagcga tgacagttgc
     1081 gatgctagca gagcattttc aggctgacgc tattataaat acaggatcgg ctggagcaat
     1141 agctagtggc ttggctattg gtgatgttgt tgttgctgat cgcttggtgt atcatgatgt
     1201 ggacgtgacg gcctttggct atgactatgg tcaaatggct gcgcagcccc tttactttga
     1261 cagtgatagc aagctggttg agacctttaa gcaggtgctt gatcaggaaa agaccaatag
     1321 tcggattggc ctgattgcaa caggagatag ctttattgcc ggccaagaca gtattgatac
     1381 catcaaagca catttcccag agaccttagc agtggaaatg gagggagcag cagtggcaca
     1441 ggcagctcaa gctgctggca agccatttat tgttgttagg gcgatgagtg acacagcggc
     1501 ccacgatgct aatatgacct tcgatcagtt tattgttgag gctggaaaaa aatcagccaa
     1561 ggtcttgata gcctttttag aggccttacc tgataaaaaa tgatgaccaa aaaaacctga
     1621 tagcctgtgg tgacagcaaa ta
//
LOCUS       DARYLJ010000104         1630 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYLJ010000104 DARYLJ010000000
VERSION     DARYLJ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1630
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..922
                     /locus_tag="TU746_001942"
     CDS             <1..922
                     /locus_tag="TU746_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0892234.1"
                     /translation="IEHRVTRDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAI
                     NLNGYGVRISGERIALDGNTTVNGAFGAKLGEFIKLKADQIIGGTIDAAKIRVINLNA
                     SSIVGLDANFIRAKIEHTITSLLEGKVIRARNGAMMIDLSNSKIDFNSNATINFNNKD
                     NALVRKDGTHTAFVHFSHATPKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRY
                     ARGYEHTALVDQAEIYGDDIVFSDDFNIDRGFKMRPSLMPKMVDLNKMYQAILALGRC
                     WLHANNTAWTFNSDTTSAIIREYNSYINGL"
     gene            931..1362
                     /locus_tag="TU746_001943"
     CDS             931..1362
                     /locus_tag="TU746_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL0892235.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLLAKVEAKLRE
                     YAKDEVDIIDQYAAKNDKGKWLVDDKGNAKLADVTKVTELNDCLDELANEPIVIKGHE
                     YSKRFIDFLEYLAEAEDEFTGAEIVLIDNILEQYEESKKGE"
     gene            1365..>1630
                     /locus_tag="TU746_001944"
     CDS             1365..>1630
                     /locus_tag="TU746_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL0892236.1"
                     /translation="MARNWKIVGKYPQPNALGVIEGTHVIITGDDGASIPQTIKKDLS
                     STNDLDVIKMVLDEFKKSEYVEIAMGEAVQKVDDLEKLSQDTAKT"
BASE COUNT          518 a          309 c          387 g          416 t
ORIGIN      
        1 aattgagcat cgtgtgacta gagatggggt tatgagtatc atcaacgagt caggcgatag
       61 cattaagcta gcgatccaaa aggctggtgg gattgacgct aagatgagcg ctaaagagat
      121 tatctcagcg attaatctta acggctatgg cgtgcggatc tctggcgagc gtattgctct
      181 ggacggtaat acgaccgtca atggggcatt tggggctaag ctcggtgagt ttattaagct
      241 caaagctgat caaatcattg gtggtacgat tgacgccgct aagattagag tgatcaatct
      301 taacgctagc agcattgttg gcttagacgc taactttatc agagctaaaa ttgagcatac
      361 gattacaagt ttgcttgagg gtaaagttat cagagctcgc aacggagcga tgatgattga
      421 cttgtcaaac tctaagattg actttaacag caacgctacc attaacttta ataacaaaga
      481 caacgctttg gtacgtaaag atggcacaca cactgccttt gtgcacttta gccatgcgac
      541 gcctaaaaac tatacaggat ctgcgctata tgcatctatt ggtattacct cgtcaggtga
      601 cgggattaac agtgcgtcga gcggtcgttt ttgcggcgct aggtttttta ggtatgcgcg
      661 aggttacgag cacacagcgc ttgttgacca agctgagatt tacggtgatg acattgtctt
      721 tagcgacgac tttaatattg atcgtggctt taagatgagg cctagcctaa tgccaaaaat
      781 ggtcgatctc aataagatgt atcaggccat tttagctctt ggccgctgct ggctacacgc
      841 taataataca gcgtggacct ttaactcaga cactaccagc gcaattatca gagagtataa
      901 ctcttacatc aacggattat aggagacaac atggatttaa cagtacaaaa caaagactta
      961 aatacgctct atagcgtact agacaaaatt aaggttacta atatgagagt aaatcgcggc
     1021 cgcgctaagc tgcttgccaa agtagaggct aagctcagag agtatgccaa agacgaggtt
     1081 gatattatcg atcaatacgc tgctaaaaac gacaaaggta agtggttagt tgatgacaaa
     1141 ggcaacgcta aattagctga tgtcacaaaa gtaactgagc ttaacgactg tttagacgag
     1201 ttagccaacg agcctatcgt catcaaaggc catgagtact ctaagcgatt tatcgacttt
     1261 ttggagtatc tggccgaggc cgaagatgag tttacagggg ccgaaattgt actgattgac
     1321 aacattttag aacaatacga agaaagtaaa aaaggagaat aattatggct agaaattgga
     1381 aaatcgtcgg caaatatcca caaccaaacg cgctaggggt tattgagggt acacatgtca
     1441 tcatcacagg tgatgacggt gcatctatcc cgcaaacgat aaaaaaagat ctgtcatcta
     1501 caaatgacct cgacgttatt aaaatggtcc tcgacgaatt taaaaaatca gagtatgtcg
     1561 aaattgctat gggcgaagca gtacaaaaag ttgatgactt ggaaaagttg agtcaagata
     1621 cagctaagac
//
LOCUS       DARYLJ010000105         1570 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYLJ010000105 DARYLJ010000000
VERSION     DARYLJ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1570
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            160..747
                     /locus_tag="TU746_001945"
     CDS             160..747
                     /locus_tag="TU746_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892237.1"
                     /translation="MIDKIKNILFDVRLSANKIENEIIFYNGFPEDSVSLSFAGNKCI
                     IEEIHRDNRIRLMETTSEYHAILYCVAILDQIFNTSKNIKITREIKEYIQEGNIIAAE
                     QLLSEKLDPTLFSLGSVEKDKLTLVKENNAYSLIFNDVQILTDLSSLRAYIVLFNYTK
                     KLERAKELYARALHDLPDCKLEFNQFVEYYLIGRN"
     gene            1183..>1570
                     /locus_tag="TU746_001946"
     CDS             1183..>1570
                     /locus_tag="TU746_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL0892238.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIY"
BASE COUNT          556 a          213 c          332 g          469 t
ORIGIN      
        1 tcagaggata ctatgtttat ttgagtatat gctggtgagg tttcagatca atttgtgaag
       61 tataaaccta atggagttga taaatatagt attcaagagc taatggatat ggttttttag
      121 atgacataac tgatttggtg aagaaaggag aaattagaat tgattgataa aataaaaaac
      181 attctttttg atgttaggct gagcgcaaat aaaatagaaa atgaaataat attttataat
      241 ggctttcctg aagatagtgt atctttatca tttgcgggta ataaatgtat cattgaagaa
      301 attcatagag ataatagaat caggttaatg gaaacaactt cagaatatca tgctatttta
      361 tattgtgttg caattttgga ccagatcttt aatactagta aaaatatcaa gattacaaga
      421 gaaatcaaag agtatataca ggaaggaaat attatagcag ctgagcagtt gctctcagaa
      481 aaattggatc ctactctttt ttcattaggg tctgtggaaa aagataaatt aacccttgta
      541 aaagaaaata atgcctatag tttaatattt aatgatgtgc aaattctaac tgatttaagt
      601 tcattacgtg cttacattgt tttatttaat tacactaaaa aacttgagag agcaaaagaa
      661 ttatatgcta gagcactaca tgacttgcct gattgtaagt tagaatttaa tcagtttgta
      721 gaatattatt tgataggaag gaattaataa aagaactatt gaaataccat atggcatttt
      781 gagttcagat gcccagtcat ggcaggaggc agcgaacaag atgctcagcg agctacatta
      841 gtaggcaata tcctaggagg attcgccgcc tcaagcgtcg ccagacggtt cagcttgaat
      901 gagccaatag cagctagggt gacgaaaccg acctacagcc gccggcagct tttgaagaac
      961 cttgagaaca gcaggctggc aagagaaagc tcgaggtttg atgattatct tcgaagagaa
     1021 taccggttaa agggaaggta ttttgcagaa agaaccacta tttcaaatgg aaagataggt
     1081 tatctttcat ctgactattt tgaaggcaag caaattccgg ttcgctctag agcttttgtt
     1141 gacgaagcag gccatattaa atggccaaat gccgatggct ttatggtgga taatttaggt
     1201 aatcctataa cggagcaggt cactctcaaa gcaggtcaaa tcattgatcg atatggatca
     1261 agtagtggtc gatttaccag tccgatagaa aatggggtga cattaccatt taataaacgt
     1321 ggattaccct acccagaagg atatcaagac tattataagt acgaattagt aatggatttg
     1381 acgaagaaaa atattgttaa tgcgtattat caatctgaag agattataag aaaacaaata
     1441 tctgtagaaa tgaaaaaatg gaatctttcc tttgatgatt tagctaatat tcagaagggt
     1501 gagattacca aagtatttgg gcaaggtgga ggaattcaga ttaaatttcc gacaggtgtt
     1561 ggtatttaca
//
LOCUS       DARYLJ010000106         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYLJ010000106 DARYLJ010000000
VERSION     DARYLJ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            71..1468
                     /locus_tag="TU746_001947"
     CDS             71..1468
                     /locus_tag="TU746_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL0892239.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYLJ010000107         1471 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYLJ010000107 DARYLJ010000000
VERSION     DARYLJ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1471
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..773)
                     /locus_tag="TU746_001948"
     CDS             complement(<1..773)
                     /locus_tag="TU746_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892240.1"
                     /translation="MFKTTVRILNWSRKYSTRIKKGFILSFLNSVFIAMPIMLSIYVF
                     NLVLGNYYGSTTYGNKEIAIVTTIMIGLVLGRYITAYFKSVNQDSIGYEMSADERVQI
                     GDILKRVPLGFFQENNPGELTTAVTTDLSFFENYSMKMIDIVINGYIMALVMIISISF
                     LSWELGVVAVSGVVLSYFCLLLLRKHSEKNSVFYLNAQSKLVESTMELIIGLPIVKAF
                     NKGDISLKNFNAAILSSKKVNLRIEKEYTPFNCLHLFSL"
     gene            complement(778..>1471)
                     /locus_tag="TU746_001949"
     CDS             complement(778..>1471)
                     /locus_tag="TU746_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0892241.1"
                     /translation="NIEIPQNSFTAIVGPSGSGKSTIIKLISRYWDVCGGEITIGGKN
                     VKDISLNQLNDLIGYVSQNNFLFNESIMENIRMGNPDASDEEVIEVSKICACHDFIME
                     LEEGYNSNVGSLGSKLSGGQRQRISIARMMLKNAPIILLDEATAFIDPDNEEKIQGAI
                     NVLTKNKTLIVVAHRLSTIKNADKIVVLKNKTIFDTGTHDELLEKCDLYKNMWLSHIG
                     AKSKSIVSNIGG"
BASE COUNT          504 a          269 c          159 g          539 t
ORIGIN      
        1 tttaatgaaa ataaatgtaa gcaattaaaa ggtgtatact ctttttctat tctcaaattc
       61 acttttttac tacttaaaat agcagcatta aaatttttaa gacttatatc acccttgtta
      121 aaagctttaa caataggaag tcctattata agttccattg tagattcaac taatttactt
      181 tgtgcattaa gataaaaaac agaatttttc tcagaatgtt tacgaagtaa caataaacaa
      241 aaatacgaaa gtactactcc agaaactgct acaacaccca attcccaaga taaaaaagaa
      301 atactgatta tcataacaag tgccattata taaccgttaa taactatgtc tatcattttc
      361 atcgaataat tttcaaaaaa agacaaatct gtggttacgg cagtagtcaa ttctcccgga
      421 ttattttctt gaaaaaatcc caatggtact ctttttaata tatcaccaat ttgtactcgt
      481 tcatcagctg acatctcata accaatacta tcctgattta cagacttaaa ataagcagtt
      541 atatatctcc ctaaaaccaa tccaatcatt atagtagtca ctatggctat ttctttattt
      601 ccatatgttg tactcccata atagtttcca agaacgagat taaaaacata tattgatagc
      661 attattggca ttgcaataaa aacagaattt aagaaagata atataaaccc tttttttatt
      721 ctcgtactat attttctaga ccaatttaat attctgacag tcgttttaaa cattgcacta
      781 acctcctata ttagatacga ttgatttcga tttggctcct atatgcgata accacatatt
      841 tttatataaa tcacattttt caagaagttc atcgtgtgta cctgtatcaa atatagtttt
      901 attttttaaa accacaattt tatctgcgtt ttttatagtt gataatctat gtgctacaac
      961 tattaaagtc ttattttttg tcaaaacatt aatagcacct tgtatttttt cttcattatc
     1021 tggatctata aatgctgtag cttcatcaag caatataata ggagcatttt tcaacatcat
     1081 tctcgctata gaaatccttt gcctttgtcc acctgaaagc ttacttccaa gacttcccac
     1141 attggaatta tatccttctt caagttccat aataaaatca tggcaagcgc aaatctttga
     1201 tacctctata acttcttcgt cacttgcatc aggatttccc atccgtatat tttccataat
     1261 actttcatta aatagaaagt tattctgcga tacataacca attaaatcat taagttgatt
     1321 taatgatata tctttaacat tttttccacc tattgtaatt tccccaccac aaacatccca
     1381 atatcttgaa ataagtttta ttattgtgga ttttcctgaa cctgatggtc caactattgc
     1441 agtaaaagaa ttttgaggta tttctatatt t
//
LOCUS       DARYLJ010000108         1308 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYLJ010000108 DARYLJ010000000
VERSION     DARYLJ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1308
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..772
                     /locus_tag="TU746_001950"
     CDS             <1..772
                     /locus_tag="TU746_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEL0892242.1"
                     /translation="SEIDQKIVRFKGFEDINDRDLRVGTFYYPKNEEKKHLILLVCGY
                     EESYLDFKSEIFFWLKNGYTVFCYDVRGTGRSQGRKVGGFTQFLKDCLLSIEYIEKNE
                     TFKKVSLVGHSMGGFAVATSLQFKTNIIDNSVIISGFDYPSEFVRKSVTNISFIFTWP
                     IEISIKLIEFLKFGNLSFLGSVSSINIFNKPVLIIQSSDDKIVKINNSIYNKKKMITN
                     KNVEYILLDNSDHNPTKNEYGGLNMDLMNQINEFIDNN"
     gene            894..1139
                     /locus_tag="TU746_001951"
     CDS             894..1139
                     /locus_tag="TU746_001951"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892243.1"
                     /translation="MIITMENYCQKNKNSIIYINQKSYSFNDSMKNNIILGKEYDDEL
                     IKTSISLSGIDVLINELAEREDTMLSNNNISLASRQI"
BASE COUNT          524 a          117 c          224 g          443 t
ORIGIN      
        1 ttctgaaata gatcaaaaaa tagttagatt taagggattt gaagatatta atgatcgtga
       61 tttgagagta gggacatttt attatcccaa gaatgaagaa aagaaacatt tgatattact
      121 agtttgtgga tatgaagaat cctatttaga ctttaaatcc gagatatttt tttggctgaa
      181 aaatggatat actgtgtttt gctatgatgt tagaggaact ggaagaagtc agggaagaaa
      241 agttggaggt tttactcagt ttttgaagga ttgcttattg tccattgaat acattgaaaa
      301 aaatgaaact tttaaaaagg tatctttagt ggggcatagt atgggaggtt ttgcagtagc
      361 gacttcgtta caattcaaaa ccaatataat agataacagt gtaatcattt caggatttga
      421 ttatccatct gaatttgtaa gaaaaagtgt aacaaatatt tcgtttattt ttacatggcc
      481 aatagaaata tccataaaac ttatagaatt tttgaaattt gggaacctgt cttttttggg
      541 atcagttagt agcattaata tatttaataa acctgtacta ataattcaat ctagtgatga
      601 taaaattgta aaaattaaca actctattta taacaaaaaa aaaatgatta caaataaaaa
      661 tgttgaatat attttattag acaatagtga ccataaccca acaaaaaatg aatatggtgg
      721 attaaatatg gatttaatga atcaaattaa tgaatttatt gataataatt gatgttaaaa
      781 attcataaga aattttagtg tattacatta gtgggtttta ttggctgaga atattatcat
      841 ttagttaatt tttaggaagg ttacgttata tgtgatagga gaattttatt ggtatgataa
      901 taactatgga gaattattgt caaaaaaata aaaacagcat aatatatatt aatcaaaaaa
      961 gctatagttt caatgatagt atgaaaaata atataatttt agggaaagaa tatgatgatg
     1021 aacttatcaa aacatcaatt agtttaagcg gaattgatgt tttaataaac gaattagcag
     1081 aaagagaaga tacaatgcta agcaataata acataagttt agcatcgaga cagatataga
     1141 gaacttcatt gattaaggca ttttacaata ataaaaaata cttttgatag atgaagggat
     1201 atcaaattta gataagtgtt gttctgatgg gatagagtct aatctttttt gaatccaaat
     1261 ctaacagtga tagtaattac acatcatttg agaaaacaaa ctagaaat
//
LOCUS       DARYLJ010000109         1284 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYLJ010000109 DARYLJ010000000
VERSION     DARYLJ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            83..1284
                     /locus_tag="TU746_001952"
                     /pseudo
     CDS             83..1284
                     /locus_tag="TU746_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
BASE COUNT          392 a          309 c          240 g          343 t
ORIGIN      
        1 gttatagggc tttatgagta tcaaaaaagt cccatatgac ctataatgaa aagcgactaa
       61 actatcattt agaaagactc atatggaaca atcacatgtt atcacacaac tactgggaat
      121 taaagaccct catatcacat tctccaaaga aatacacgac atgaaaactc ataaggaatt
      181 gaaagctgtc cttgactacg atgccccacc ttgccctaac tgccaaagtc agatgggcaa
      241 gtacgacttc caacgggaat ccaaggtccc ttttctcgat tgcgcaggct acaagacttt
      301 gattcgcctc aaaaagcgcc gtttcaaatg tcagttttgc ggaaaaatta ctgtcgctga
      361 gacttctcta gtccctaaaa accatcaaat accaaccatc gtcaaacaga aggtggccca
      421 gcttctcatc gagaaagtct ccatgaccgc tatcgctgat agactatcca tctccacctc
      481 aaccgtcatg cgaaagctca acgagttcac gttcaagtct catttgactt atttacccga
      541 acatatgtcc tgggatgaat atgcctttaa gaagggcaag atgagcttta ttgctcagga
      601 ctttgacacc aacaacatca tcgctatttt ggatggacgg acgaaagctg tcattcgcaa
      661 ccacttcctg agatatcctc ggcaggtcag aaacgacgtt aaactcatca ccatggatat
      721 gtttaccccc tattacaacc tggctaagat gcttttccca aacgcttaga ttgtccttga
      781 tcgtttccac attgtgcaac atttgggacg tgccatgaac cgtatccgta ctcaaatcat
      841 gaactctttt gatcgaaaat cccacgaata caaggctttg aaacgttact ggaagctgat
      901 tcaacaagat agtagcaaac ttagtgacaa gcgtttttac cgcccgactt ttcgcatgca
      961 tttgacaaac aaggaggtgg tcgagcgtct tttgagctac tctgacgagc ttagaaagca
     1021 ttatgacctt tatcagcttc tgctttttca cttccaggaa aagcaagctg accacttttt
     1081 cggcctgatt gaggagcaga tagacagtag caatcctctc tttcagaccg ttttcaagac
     1141 ctttttgaaa gacagagaca agattgagaa cgcactggat ttgccttatt ctaacgctaa
     1201 actggaggct accaataatc tcatcaaagt catcaagcgc aatgcttttg gatttcggaa
     1261 ctttgaaaac tttaaaagac ggat
//
LOCUS       DARYLJ010000110         1139 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYLJ010000110 DARYLJ010000000
VERSION     DARYLJ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1139
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            309..659
                     /locus_tag="TU746_001953"
     CDS             309..659
                     /locus_tag="TU746_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0892244.1"
                     /translation="MFSTFEKIKELCKSRGISIAKLEENLGLSKNAIYAIKRNQPSAE
                     RLQEIADYFHVSTDYLLGRTDNPKIAQSDHTPSAIDLKKDAEETFFFDGHELNDEDID
                     LITSILETRIKNRK"
     gene            673..1077
                     /locus_tag="TU746_001954"
     CDS             673..1077
                     /locus_tag="TU746_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL0892245.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     TYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLREELSYWDNVEEFNYVR
                     FMQQYDLTSFVDEVMVKEEYYNLTGYYDKKSF"
BASE COUNT          418 a          192 c          190 g          339 t
ORIGIN      
        1 cgatcgggag ttttttattt aaatgaaaag cgaatttttt tgcgaaaaat tttttatagt
       61 ttactcttga caatgattag agaataaact acaatcaaca tatagaaaaa aacactaaca
      121 aatagcttaa taacactaac tatcttaagt cgccaaactt tattttttta gttttatttt
      181 cgctttttgt ttcgcttatt tattcgcttt acaaattata ttttagagta ttctcttgtt
      241 tttgtcaaca ataaaataga tatttctcta aaatattttt cgtgatgctt agaaaggttg
      301 atatatcaat gttttcaaca ttcgaaaaaa tcaaagagct ttgcaaaagt agaggaatct
      361 ctattgcaaa gctagaagaa aatcttggat taagtaaaaa cgctatttac gcaatcaaga
      421 gaaaccagcc gtccgctgaa cgtcttcaag aaatcgctga ctacttccac gtctctacag
      481 attacctttt aggtcgcaca gataatccta aaattgcaca aagtgaccat accccgtctg
      541 caatcgatct aaaaaaagat gcagaagaaa ctttcttctt cgatgggcat gaactcaacg
      601 acgaggatat agaccttatc acatctatat tggaaacgcg catcaaaaat agaaaataga
      661 gaggacagct ctatgatgac accagaaaca gtctgtcagg aaaagggaat cgatttagtg
      721 tacttcgacg gtagggggac aaacacccct ggaatgttta acaaaaaaca caacgtcatt
      781 gcgattgaca cttatcttga cggcacatac aagcacaaag tcatctatca tgaactagga
      841 catagagaac atactgcgag ttattacaag ctaaacaaag aaaaagcaga gctacaagct
      901 gatagatgta tgatacatca cttgctgagg gaagaattgt cttattggga taatgtagag
      961 gaatttaact acgtccgatt tatgcaacaa tacgatctaa cttcatttgt cgatgaagtc
     1021 atggtcaagg aagagtatta taatttaaca ggttattatg acaaaaagag tttttaattc
     1081 tagctttcaa gtagctggaa cagtatatca tcaaacactt attataaaaa tttaacaaa
//
LOCUS       DARYLJ010000111         1032 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYLJ010000111 DARYLJ010000000
VERSION     DARYLJ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..>1032
                     /locus_tag="TU746_001955"
     CDS             <1..>1032
                     /locus_tag="TU746_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="equibactin biosynthetic protein"
                     /protein_id="HEL0892246.1"
                     /translation="ILSINIGKTEVIIKAFNEMGRKNLDTDMRMLFSMTVGYASGRLT
                     LSSPLGPVLWEQSPNVPKIDLIPRFLDGNDNEGCSKPWLSILYEGDTYYKSYVYRNIW
                     VEAIMDDLKEFVFEDKSKKQSNSMKIQHQLETSILWQKIMNSLGYPKQKSLCRNKYID
                     PDKFKRNEVSCYSIRESVDELNTVCRDTMFYHLSKHIPRQGISMLSLVEALMFKDKYK
                     KIIVRWINYLVDFKYLEKNRGYIFSKKEKIDEIDLLKKWDVLESKWNKDAMPINVFQY
                     FRNNARELSALLKEDINANEILFVEGSDVVAKDLYSKTAIARYLNELIVKKIKEFNGN
                     EDLTILELGG"
BASE COUNT          411 a           90 c          200 g          331 t
ORIGIN      
        1 attttatcta taaatattgg taaaacagag gttattataa aggcatttaa tgaaatgggt
       61 aggaaaaatt tagatacgga tatgcgtatg cttttttcta tgactgtggg atatgcgtct
      121 ggtaggctaa ctttatcaag tcctcttgga ccagttttat gggaacaatc acctaatgta
      181 cctaaaatag atcttatacc aagattttta gacggcaatg ataatgaagg atgtagtaaa
      241 ccttggttat caattcttta tgagggagat acatattata aatcatatgt atatagaaat
      301 atttgggttg aagcaataat ggacgatttg aaagagttcg tttttgagga caaaagtaaa
      361 aaacaaagta atagtatgaa aattcaacac caattggaaa cttctatatt atggcaaaaa
      421 attatgaata gtttagggta tcctaaacaa aaatcattat gtaggaataa atatattgat
      481 cctgataaat ttaagagaaa tgaagtgtca tgttacagca taagagaatc tgtagatgag
      541 ttgaatacag tttgtagaga tacaatgttt tatcatttga gtaaacatat acctagacaa
      601 gggatatcaa tgttatcatt agtggaagct ttgatgttta aagataaata caaaaaaatt
      661 atagtgcgtt ggataaatta tttggtagat tttaaatact tagaaaaaaa tagaggatat
      721 attttttcta aaaaggaaaa gatagatgaa atagacttgc ttaaaaaatg ggatgtgtta
      781 gaaagtaaat ggaataaaga tgctatgcct ataaatgtat ttcaatattt tagaaataat
      841 gcgagagagt taagtgctct attaaaggaa gatatcaatg caaatgaaat tttatttgta
      901 gaaggtagtg atgtggttgc caaagatttg tattcaaaaa cagcaatagc aagatatttg
      961 aatgaattaa tagttaaaaa aattaaagaa tttaatggaa atgaagattt aacaatattg
     1021 gagctgggtg ga
//
LOCUS       DARYLJ010000112         1027 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYLJ010000112 DARYLJ010000000
VERSION     DARYLJ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1027
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            145..1027
                     /locus_tag="TU746_001956"
                     /pseudo
     CDS             145..1027
                     /locus_tag="TU746_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          350 a          186 c          220 g          271 t
ORIGIN      
        1 gacataaaat ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt
       61 caaatctatg agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt
      121 attgcagaat ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt
      181 gtccaaaaag gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa
      241 gttctgattg atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct
      301 agtatgcttt caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa
      361 agaagaggga ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca
      421 gagttggagc gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa
      481 aagctgagag aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc
      541 aagaattaat cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt
      601 caacctatta ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg
      661 agctcattca aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc
      721 tggaactaag aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg
      781 tcatgggctt aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg
      841 ttggcaaaaa ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga
      901 agtgctatac cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg
      961 ttcttgacgg ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga
     1021 agcaagt
//
LOCUS       DARYLJ010000113         1000 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYLJ010000113 DARYLJ010000000
VERSION     DARYLJ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
BASE COUNT          293 a          139 c          171 g          397 t
ORIGIN      
        1 tttgaaacca cattagtgcc tgcaaataaa tctaaaaaaa acttcttcat caccagtttt
       61 atgtttgtct agcatggtct taatttctgt caacaataat tttttagaac caatatatct
      121 cattctacat ccttaatcat cctttagttg tttcattata gcatattcat gttgaagttc
      181 caatatttta tttgaaaaat tatcttttgc tgtatttctt tattgtagtt tttaagctta
      241 gtttatatgt tgttgattaa agggaagaag aacttaggtt atctaaattg aggaattcgt
      301 ctgtaggtaa caatgtatta tgtggccgag agatttattt tatatattaa tgagatataa
      361 gacccctatc ccgtccagcg tgacagactt gctatggaaa agcttatttt gaggctgtct
      421 gaggcttgct tatgtgtgac aagcatttag gctagaacgc tcaccttttt tactgcaagc
      481 aaagctttag aagctattgc aagatacttt taggcttgtt actaagcggg tcatctctat
      541 catctcctag agagtagtgg aggctatgac agtttagcat atatggtttc tctaatgatt
      601 tgacgatgta aaaccataac tactgttatt gtagggatta tgtataatat gtataaaaag
      661 agaagggctt gtttctcagc gttatcattt tacctataat gtcgctgcca gtttgcaagg
      721 ctgctgagat tagtagcttt ttggctattt ttctcatctt ttgtcttatt tttattaaaa
      781 ataatgaatt tataaagata atttttcaaa gaatagtctt taagttgaca gtagtatcat
      841 gtggcgattt ttgtcttggt ttttgcattt atttcggttt ttttatcttt aattaagtta
      901 ctaatattct gattatgtta gtaaaatgac attctcataa aatgtctaaa aaaggctaat
      961 ttgtcaaggt attatcataa ggcttgattt tataagctat
//
LOCUS       DARYLJ010000114          998 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYLJ010000114 DARYLJ010000000
VERSION     DARYLJ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..998
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..217)
                     /locus_tag="TU746_001957"
     CDS             complement(<1..217)
                     /locus_tag="TU746_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="HEL0892247.1"
                     /translation="MYNIGVLGCNGNIGSLFMEKVSKWEDNYIYAVSRSHMNFIKKDN
                     IEYIFFDAENIEKLDKFCSKCDVIVNCT"
     gene            complement(237..>998)
                     /locus_tag="TU746_001958"
     CDS             complement(237..>998)
                     /locus_tag="TU746_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0892248.1"
                     /translation="GKDMELSSHNIVFDKVRFAYDKIPIIKDVSFEIKENTVTAIIGP
                     SGSGKTTICNLISRFYDVSGGSIKIGNVNIKNLTLSSLLSNISTVFQKVYLFNDTIEN
                     NIKFGNPNVSKEEIINAAKKSHCHEFIMNLPNGYETIVGEGGDFLSGGEKQRISIARA
                     MLKDAPIIILDEATSSIDPENEYLIQRAISNLSKGKTVIIIAHRIVTIEEADQIIVLK
                     EGEIAQIGKHTELMSQDGLYRDYMRIRGKTEDWKI"
BASE COUNT          308 a          204 c           92 g          394 t
ORIGIN      
        1 cagtacaatt tacaatcaca tcgcatttag aacagaattt gtctaatttt tctatgttct
       61 ctgcatcaaa aaatatgtat tctatgttat ctttcttaat aaaattcata tgacttctcg
      121 atacagcata aatataatta tcttcccatt tagacacttt ttccataaaa agcgaaccta
      181 tattaccatt gcaacctaaa actcctatat tatacataaa cctcctccta tctatattat
      241 attttccagt cctctgtttt acccctgatt ctcatataat ctctatacag accatcttgg
      301 ctcatcagtt ctgtatgctt tcctatttga gcaatctctc cttctttcaa aacaattatc
      361 tgatctgctt cttcaattgt tacaattcta tgagcaataa taattacagt cttaccttta
      421 ctcaaattcg atattgctct ttgaattaaa tattcgtttt caggatctat gcttgatgtt
      481 gcttcatcca aaataataat tggagcatct tttagcattg cccttgctat agatattctt
      541 tgtttttctc caccagataa aaaatcacca ccttcaccaa caatagtttc atatccattt
      601 ggcaaattca ttataaattc atgacaatgt gacttcttcg ctgcatttat tatttcttcc
      661 ttacttacat tcggattacc aaattttata ttgttttcga ttgtatcatt aaacaaatac
      721 accttttgaa atactgtact tatatttgaa agtaaacttg ataaagtcaa attttttata
      781 tttacatttc caatttttat actcccacca cttacatcat aaaaacgaga aatgagatta
      841 caaattgttg ttttacctga ccctgatggt cctataatag ctgttaccgt attttccttt
      901 atctcaaatg aaacatcctt tataattggg attttatcat atgcaaatct tactttgtca
      961 aaaacaatat tatgactact caattccatg tcttttcc
//
LOCUS       DARYLJ010000115          931 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYLJ010000115 DARYLJ010000000
VERSION     DARYLJ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..931
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            39..>931
                     /locus_tag="TU746_001959"
     CDS             39..>931
                     /locus_tag="TU746_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892249.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEK
                     LLSISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISW
                     EMALAMFITVPFALMAYKKLMGNFNQLYEAQMKSNKYMNSTIVEYISGIEVIKTFNQD
                     SNSYKKYKDAVNLYKDHTLNWFKSTWSIMNFASSILPSTFLGTLPVGMILYLNGTLTP
                     AEFCICLMLSLGIVIPLTQFT"
BASE COUNT          328 a          115 c          166 g          322 t
ORIGIN      
        1 agtttatgaa ttttagataa aggaggtgga gaagttacat gagcaacaaa aactggataa
       61 atactatatt agattttgct tcagattgta aaggaaagtt gattttatca gtagttatgg
      121 ctagtatagg agtgttcttt agcattatac cttattggtc agtatataaa cttatggcag
      181 tctttataga acaaaaagca actggagaag atgtattgta ttatggagcg attggtatta
      241 ttgcatattt tatcagatat atttgccatg gagtatcaac aatattatct catatatccg
      301 cttacacaat cttaagaaat ataagagaaa atttaggtga aaaattgctc agtatttcta
      361 tgggaaatgc gtcaaaaaag acaataggag aatataagtc aattattgta gacaaagttg
      421 aaacaattga gatgcctcta gcacatatca taccagagtg tgttgctgca ttgcttttat
      481 cactaggtat tgcaatattt atggtcttca taagttggga gatggctctt gcgatgttta
      541 ttacagtgcc ttttgctttg atggcatata aaaaactaat gggtaatttt aatcagcttt
      601 atgaagctca aatgaaatct aacaagtata tgaattctac aatagtagaa tatattagtg
      661 gtatagaagt tataaaaact tttaatcagg atagtaattc atataaaaaa tataaagatg
      721 cagtaaattt atacaaagat catacattga attggtttaa atcaacttgg agtattatga
      781 attttgcaag ttctattttg ccatcaacat ttttgggaac attacctgtg ggtatgattc
      841 tatatttaaa cggaacactg acacctgctg aattttgcat atgtctaatg ctttctcttg
      901 gaatagtaat tcctctcact caatttacaa a
//
LOCUS       DARYLJ010000116          926 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYLJ010000116 DARYLJ010000000
VERSION     DARYLJ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..926
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            99..>926
                     /locus_tag="TU746_001960"
     CDS             99..>926
                     /locus_tag="TU746_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0892250.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     "
BASE COUNT          302 a          192 c          281 g          151 t
ORIGIN      
        1 atcagcagct atttcttaca tttagctagc gtgttaagat agctattgga aaagattttt
       61 aggaatactt catatttcta tcatcaaagg agagagaaat gataaataaa agaaagaaaa
      121 aacttatcta caggtatggt gtctgctcgg cagcagttat cctagcagcg cttgctagcc
      181 taggaacatg taaagaagca aaagcattat ctggtccgcc aggataccca cttactcgtg
      241 atttctcccg taacttccta gaagaaaata ctgcaaaata tttagatcaa ttaagagaac
      301 atctacagca cagatttagt gaacttgaga gcttaacaag aaaattagag aaagaaggcg
      361 gtacccgagg tccagcaggg cctccggggc cagccggacc taaaggggaa cgtggcgaac
      421 cagggcctgt tggacctatg ggacctagag gtgaacaagg tcctaaaggc ttagacggag
      481 cacgtgggcc cgagggacag caaggaaaac ctggacctgt cggacctcaa gggccggcag
      541 gtccagcggg gcaaaaaggg gaaaccggac ctcagggacc tcgtggagat aagggcgata
      601 ctggagaaac tggaaagcaa ggaccagcag gagaacgtgg gccagctgga cctcagggac
      661 cgcgcggaga caagggtgaa aacggtgcac ccggtgagca aggccctatt ggtccaaaag
      721 gtgagactgg acctaaaggt gacaagggag aacgcggcga aaagggcgac caaggtcaac
      781 gtggtgaaaa gggcgaccaa ggtcaacgtg gtgaaaaggg cgaccaaggt caacgcggtg
      841 aaaaaggcga gcaaggccaa cgtggtgaaa agggcgagca aggccaacgt ggtgaaaagg
      901 gcgagcaagg gccacgcggt gaaaaa
//
LOCUS       DARYLJ010000117          834 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYLJ010000117 DARYLJ010000000
VERSION     DARYLJ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..834
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(330..>834)
                     /locus_tag="TU746_001961"
     CDS             complement(330..>834)
                     /locus_tag="TU746_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0892251.1"
                     /translation="SGVGKTTLAKLILNYYPKHLYDGEIRIDGRNIAEINSESLYKKI
                     AFVQKNDFLVEGNVSDNIKLDGSLNLTDKLKDSLGFDETFLNKKLFRVQSLISEGEKQ
                     RIDLARFLNRRYSIYIFDEPTGNLDPARSKAILDYILSIKNAIIIVITHNQDIKTLEQ
                     FDEVICL"
BASE COUNT          269 a          158 c           85 g          322 t
ORIGIN      
        1 tctttgatac tattattccc gtcacaacaa gaaataaaat ctgaccaaaa aattgagttt
       61 cctttgattt ctagaacatc attatcatca gctcctatcc ttaatttatc attttgccat
      121 gaatatacaa tcctatcctg attccatttt ggaaaaaaat tattcatttt attgtccttt
      181 ctatatttta caaaggcatg caaattctca ttgcatgcct ttgtgattaa acaaaatacc
      241 aatttgtggt ttgttcattt cgaacttcga caaactctag ttctaaaact tcaaaatctt
      301 ccataatcat gttcatcacc ccctttcatt tacaaacaaa tgacttcatc gaattgttct
      361 aacgttttta tatcttggtt gtgagtaatc acaatgatga ttgcattctt tattgataaa
      421 atataatcca atatggcttt agatctagct ggatcaagat taccagttgg ttcatcaaaa
      481 atataaatag aatatctacg gtttaaaaat cttgctaaat caattctttg tttttctcct
      541 tctgagatta aagactgaac tctaaataat tttttgttta aaaatgtttc atcaaatcct
      601 aaactatctt tgagcttgtc tgttagattc aaactcccat ctaatttaat attgtctgaa
      661 acattacctt ccacaagaaa atcatttttt tgaacaaacg caatcttctt atacaaactt
      721 tctgagttaa tttcagcaat atttcttcca tcaattctta tttccccatc atataaatgc
      781 tttggataat aatttaatat cagttttgct aatgttgttt tcccaacccc cgaa
//
LOCUS       DARYLJ010000118          824 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYLJ010000118 DARYLJ010000000
VERSION     DARYLJ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..824
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..>824)
                     /locus_tag="TU746_001962"
     CDS             complement(<1..>824)
                     /locus_tag="TU746_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL0892252.1"
                     /translation="IQFVDIETIKAKMRNMVPIYMVPDDIVLLKNMPQNKNGKVDRKK
                     LEEIYKDKKLQGNIFDMILDDREIETLKDIWKEIFGYDTKYRTSFFSNGGDSLIATKL
                     SAKIEEKFKISFSIKDVMENITIEAQAQVIKDRIAEQRFADKISVIEETITEEEFDLT
                     DVQHAYYVGRNKDMILGGVSTHCYFEIESSDIDVNKLEKAWNYLIKIHPMLRAIITEN
                     GKQKILQEVEYYKIMTSADSELIIRDIMSQQVLNLDKWPIFDIRISKREDKADIIH"
BASE COUNT          239 a          171 c           81 g          333 t
ORIGIN      
        1 atatgaatta tatccgcttt atcctcacgc ttgctaattc ttatgtcaaa tataggccat
       61 ttatccagat taagcacctg ttgtgacata atgtcacgga taatgagttc tgaatctgca
      121 ctagtcatta ttttataata ttctacctct tgcagtatct tctgcttacc attttcagtt
      181 ataattgctc gtaacatcgg atgaattttt attaaataat tccacgcttt ctccaactta
      241 tttacatcta tatcacttga ttctatttca aaataacaat gagtagaaac tcctcctaaa
      301 atcatatcct tgtttcttcc aacataataa gcatgttgaa catccgtcaa atcaaactct
      361 tcctctgtaa tagtttcctc tatcacgcta attttatccg caaaacgctg ctcagcaatt
      421 ctatctttaa tcacttgggc ttgtgcttca atagtaatat tttccattac atcttttata
      481 ctaaaactta ttttgaattt ttcctctatt ttagctgata gttttgttgc aattagagaa
      541 tctccaccat ttgaaaaaaa gctagttcta tactttgtat catatccaaa tatttctttc
      601 catatatcct ttaaagtttc tatttctcta tcatctaaaa tcatatcgaa aatattacct
      661 tgcaattttt tgtccttata tatttcctct agttttttcc tatcaacttt cccattttta
      721 ttttgtggca tatttttgag taatactata tcatccggca ccatatatat cggaaccata
      781 tttctcatct tcgccttaat agtctcaata tcaacaaact gtat
//
LOCUS       DARYLJ010000119          814 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYLJ010000119 DARYLJ010000000
VERSION     DARYLJ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..814
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..327
                     /locus_tag="TU746_001963"
     CDS             <1..327
                     /locus_tag="TU746_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892253.1"
                     /translation="AGLARAAAERTQKMINLQTIHVLTSGGKIEPDIYKGMLELIEPA
                     KKGQYQEHDVFTVLDDKHEDLAGEGKLVFVYVNEAFEYDKQTLKDLESEDKVTVIKYA
                     DLVKGK"
     gene            340..630
                     /locus_tag="TU746_001964"
     CDS             340..630
                     /locus_tag="TU746_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892254.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            633..812
                     /locus_tag="TU746_001965"
     CDS             633..812
                     /locus_tag="TU746_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892255.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
BASE COUNT          260 a          139 c          203 g          212 t
ORIGIN      
        1 gctggtttgg ccagggcagc tgcagagcgc acacaaaaga tgattaactt gcaaactatc
       61 cacgttttga caagtggtgg caagattgag cctgatatct ataaaggcat gcttgagctt
      121 attgagccag ctaaaaaagg tcagtatcaa gagcatgatg tctttactgt gctagatgac
      181 aagcatgagg acttggccgg cgagggtaaa cttgtctttg tctatgttaa cgaggccttt
      241 gagtacgaca agcaaaccct caaagatctg gaatcagagg ataaagtcac agttatcaag
      301 tacgctgatt tggttaaagg caaatagtga ggtgattaga tgatagattt tgtgcaaata
      361 ggcacttttt gtggcgctgc tctgtctatc tttggtgttt ggggatttat cgtcaatcct
      421 tttaaaaaag cgctggaggc taacgagcta gccatggccc aactcaaaga ctcgatcaag
      481 gagctagcct acgagctaaa aaatcttgat cgtgatggag agataaccaa aaagattatc
      541 gatcggcatg aggagcgttt aggacgtgta gaggacgaca ttattgtcaa taaagagcaa
      601 atcaaaacat tatttaaaaa aggagactaa aaatggataa atggtttaaa aaagtagcaa
      661 tcaaaacaat taagacaatg gcccaaaccg ctgtaggggt tattggatca agcgcattga
      721 ttactgacgt caactggcag gtggtggcct caacagttat tatgtcaggt attgtctgcg
      781 tcttgatgaa tgtgtctgac atcaaggaat agca
//
LOCUS       DARYLJ010000120          796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYLJ010000120 DARYLJ010000000
VERSION     DARYLJ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TU746_001966"
     CDS             complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TU746_001966"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL0892256.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDL"
BASE COUNT          188 a          210 c          198 g          200 t
ORIGIN      
        1 aggtcgtcct tgacctgagg gtgcttgaga gcatagtcaa gtgaggtctt cataaagcca
       61 aacttgtccc caacatcata ccgctctccc ttaaactccc tggcaaaaac ccgctgagtc
      121 ttgttgagct tgtcaatcgc atcggtcagc tgaacctcat tgccagcccc aggcgcctga
      181 ttctccaata tggcaaaaat ctcaggcgtc aacaaataac gtccaataat cgctaagtca
      241 ctaggtgcct catcaggact tggcttctca acaaaggtct ccacactata caagccctta
      301 acagccttcc cttgcggtgc aatcacgcca taattggaaa cctcctcatg cggaaccctc
      361 atcacagcaa tcgttgaggc gtgtgtacag tcataatcct cgataagctg cttggtcaag
      421 ggcttggcac taggattggt aatatccatg aggtcgtctc ctagcatgac cacaaagggc
      481 tcattgccca caaaggcctt ggcttggagg acagcgtccc ctagtcctct agggtggctc
      541 tgacgaatga agtgcaggtt gatggcagtg gtctcatcaa cgagcttgag cagctcggtt
      601 ttgcccttgg cttggagatt gtattcgagc tcgaagttgg agtcaaagtg gtcttcgata
      661 gagcgtttgg ccttgccggt gacgacaaga atctcctcga taccggcctt tagggcttcc
      721 tcgacgatga attgaatggt tggcttatcg acgattggga gcatttcctt ggccagtgcc
      781 ttagtggcag gcagga
//
LOCUS       DARYLJ010000121          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYLJ010000121 DARYLJ010000000
VERSION     DARYLJ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..>672)
                     /locus_tag="TU746_001967"
     CDS             complement(<1..>672)
                     /locus_tag="TU746_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL0892257.1"
                     /translation="AGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALAPQKQLTVIG
                     HQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGDTPLIRGESL
                     KALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANEAEQEVKEIN
                     TGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLKDFDESLGVN
                     DRLALA"
BASE COUNT          140 a          183 c          152 g          197 t
ORIGIN      
        1 gctagggcta ggcgatcatt aacccctagg ctctcatcaa aatccttcag caggtaagcg
       61 ccaacccttt cttggccagc cttgaaaata ctgatcacat cggttaggta gtactcccct
      121 tgggcattat cagtcgtgag atgctttaga gcctcaaaga ggcgcttatt gtcaaagata
      181 taagtccctg tgttgatctc cttgacctct tgctctgcct cattagcgtc cttttgctca
      241 acgatattga ccacctctcc tgctacattg cgaatgattc gtccatagcc aaagggatcc
      301 ttggcattgg ctgtgagaat ggttgccaca ttcttttctc tgatatgata gtctagcaga
      361 gccttgagac tttctcctct gatcaagggg gtgtcacctg caatcactag ggtttgtccc
      421 tctaagccag atagctcctc ttctgccatc atgactgcat ggcctgttcc tagctgctcc
      481 tcttgcacca ctgtcagtga ttgatcacct aggacggcac gtacctgctc tgcctgatga
      541 ccgatcactg tgagttgctt ttgaggagct agggctgaga cgctattgag gacatgctcc
      601 agcatgctta agcctgatac cttgtgcagc accttgggaa gccctgattt catgcgggtt
      661 ccctttccag ct
//
LOCUS       DARYLJ010000122          635 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYLJ010000122 DARYLJ010000000
VERSION     DARYLJ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            185..>635
                     /locus_tag="TU746_001968"
     CDS             185..>635
                     /locus_tag="TU746_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0892258.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKGDQGQK"
BASE COUNT          252 a          114 c          153 g          116 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 acgaaaccaa agattgaaat tgatagatag ctattcccac tctaatagtg gacatgttag
      121 aatttccttt gggaaaggaa gttacaggaa actaagactg tttctaccac aaaaggagag
      181 aaagatgaga tacacattaa acaaaaacaa gcgtgctcgt aactacgggc tatgctcagc
      241 agctatcgct ctagcagcag tagccagcct aggaacagct ggcagcgcta aagctgagga
      301 agcaaaaaca ttagaccaac tacctaatcc agaagagcaa attctatata attattggga
      361 cacaaatgat cagaaagcaa gagaatatct tggagaccta tacggtttcc taaaatctta
      421 tttaggagag ttggaaaaaa aagctaaaga gcctggacct gctggaccta aaggtgaaaa
      481 aggcgaaaaa ggcgaaaaag gcgagaccgg tccgatgggg cctcaaggcc taaagggtga
      541 ggacggaaaa gacggcgcac ctggagaaaa aggagaaaaa ggtgatccgg gtatccaagg
      601 ccctaagggg gaaaagggtg accaaggcca aaaag
//
LOCUS       DARYLJ010000123          539 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYLJ010000123 DARYLJ010000000
VERSION     DARYLJ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..>539)
                     /locus_tag="TU746_001969"
     CDS             complement(<1..>539)
                     /locus_tag="TU746_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0892259.1"
                     /translation="TVFNAPSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYL
                     GDDELGISRWVDGKAGIGRHSLAAYRFNSKGQVIDRKGHPAAAQAPALATLRSRLTDY
                     RRLKKQYAASNGISSSEEFYLDQFQSRAVAQALEQTTQLAQEEIIARRKEAVAEAEAL
                     HQKTRDMPFFVSELSWAEL"
BASE COUNT          130 a          138 c          127 g          144 t
ORIGIN      
        1 tctagctccg cccagctcaa ttcactcaca aaaaagggca tgtctcttgt cttttggtga
       61 agtgcctctg cctctgcaac cgcctccttc cgacgagcaa tgatctcctc ttgggcaagc
      121 tgagtggtct gctccaaagc ctgtgcgact gctcgagact gaaattgatc aaggtaaaac
      181 tcctctgagc tactaatacc gttagaagcg gcatactgtt tcttaagccg gcgataatcg
      241 gttagtctgg atcttagggt agcaagagca ggtgcttgag cagcggcagg gtgaccctta
      301 cggtcaatca cctgcccctt tgagttgaag cgataagcgg ctaagctatg acgtcctatt
      361 cccgccttac catcaaccca tcttgaaatc ccgagctcat catctccaag gtaagtgcct
      421 aggtttccaa tgtagtcatt gttaatgcgg tagctgtgat agagtccctt gttggcttta
      481 acaaagtcaa tagcctcctt ggagaggtta ttaacagagc ttggcgcatt aaagacagt
//
LOCUS       DARYLJ010000124          498 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYLJ010000124 DARYLJ010000000
VERSION     DARYLJ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            19..91
                     /locus_tag="TU746_001970"
     tRNA            19..91
                     /locus_tag="TU746_001970"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Asp,seq:gtc)
     gene            95..167
                     /locus_tag="TU746_001971"
     tRNA            95..167
                     /locus_tag="TU746_001971"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:128..130,aa:Lys,seq:ttt)
     gene            173..254
                     /locus_tag="TU746_001972"
     tRNA            173..254
                     /locus_tag="TU746_001972"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Leu,seq:tag)
     gene            262..334
                     /locus_tag="TU746_001973"
     tRNA            262..334
                     /locus_tag="TU746_001973"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Thr,seq:tgt)
     gene            346..417
                     /locus_tag="TU746_001974"
     tRNA            346..417
                     /locus_tag="TU746_001974"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:378..380,aa:Gly,seq:gcc)
BASE COUNT          106 a          112 c          156 g          124 t
ORIGIN      
        1 tcccataagt tatgaatagg tcccgtagtg tagcggttat cacgtcgccc tgtcacggcg
       61 aagatcgcgg gttcgattcc cgtcgggacc gtaggactcg ttagctcagt tggtagagca
      121 tttgactttt aatcaaaggg tcactggttc gagcccagta cgggtcataa aggcgggttt
      181 ggcggaattg gcagacgcac cagatttagg atctggcgct taacggcgtg ggggttcaag
      241 tcccttaacc cgcatagata ggccggctta gctcagttgg tagagcatct gatttgtaat
      301 cagagggtcg cgtgttcaag tcatgtagcc ggcattgata gagttgcgaa cgtagttcag
      361 tggtagaaca ccaccttgcc aaggtggggg tcgcgggttc gaatcccgtc gttcgctttt
      421 ggggagccgg ggtggcggaa ctggcagacg cacaggactt aaaatcctgc gatggttaac
      481 atcgtaccgg ttcgattc
//
LOCUS       DARYLJ010000125          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYLJ010000125 DARYLJ010000000
VERSION     DARYLJ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(68..139)
                     /locus_tag="TU746_001975"
     tRNA            complement(68..139)
                     /locus_tag="TU746_001975"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Arg,seq:ccg)
BASE COUNT          144 a           82 c           64 g          147 t
ORIGIN      
        1 attggtagat tttctgtcta acttttgggg tgcgggtcat ttaataggct tttttatatc
       61 gtttctatcc accttgaggg aatcgaaccc ccatctcaag aaccggaatc ttgcgtgata
      121 tccattacac taaaggtggc acctttaacc ataccactac agtatagcat aaaagtggat
      181 attttaaaat ccttttttct aaaaagatca caccatacac atgacgaaaa tgcatgtcat
      241 tattttctag tcatatgcat tttatcacta tatttttaat attttgacat catcagtggt
      301 tcaaatacag tttagttata ccataaatgt tcttgaaaaa acacattgat tacgaaaatg
      361 ctaccagaaa atgtcagttt ctccatgcat tggtatgcta aaaaaatact ataaaaagct
      421 gagcaattac ccagctt
//
LOCUS       DARYLJ010000126          417 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYLJ010000126 DARYLJ010000000
VERSION     DARYLJ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            complement(<1..>417)
                     /gene="glmU"
                     /locus_tag="TU746_001976"
     CDS             complement(<1..>417)
                     /gene="glmU"
                     /locus_tag="TU746_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL0892260.1"
                     /translation="SRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHIG
                     NFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAFI
                     GSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGR"
BASE COUNT          103 a          133 c           81 g          100 t
ORIGIN      
        1 cgccctatag ccacactgtc tgccggcact gactgggcta tcgtagaccc tgcggctgtt
       61 aaagcattct ccccaacctc tactggagct atcaaagtcg aatgactccc aataaaagcg
      121 tgatcgccaa tcactgtctg gtatttccgt tgaccatcat aattaaccgt aatgcttcct
      181 gcaccaatat taacctctga gccaatctcg gcattcccca ggtaagtcaa atgccctgcc
      241 ttggtattgg cccctagatg agacccctta acctctacaa agttcccaat atgaacgctc
      301 tcatcgagct gggagtctgg gcgaatgtgc gcatagggcc ctactgtcac accatctgct
      361 aggactgaat cctcaatcac tgactggctc accactacgc cctcaccaag cctcgaa
//
LOCUS       DARYLJ010000127         8508 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848970-rid18538373.guided.067, whole genome shotgun sequence.
ACCESSION   DARYLJ010000127 DARYLJ010000000
VERSION     DARYLJ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848970
            Sequence Read Archive: SRR25004176
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787521.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787521.1
            Genome Coverage       :: 112x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:03:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,983
            CDSs (total)                      :: 1,947
            Genes (coding)                    :: 1,863
            CDSs (with protein)               :: 1,863
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 30 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 31 of 84
            Pseudo Genes (multiple problems)  :: 8 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8508
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848970-rid18538373.guided.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KY"
                     /collection_date="2021-03-01"
                     /collected_by="Murray State University Breathitt
                     Veterinary Center, Hopkinsville, KY"
     gene            <1..304
                     /locus_tag="TU746_001977"
     CDS             <1..304
                     /locus_tag="TU746_001977"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0892261.1"
                     /translation="YRDSCLGLAANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFE
                     AEESCLSLIGQRKTKRYQEIKVDYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(495..2501)
                     /locus_tag="TU746_001978"
     CDS             complement(495..2501)
                     /locus_tag="TU746_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL0892262.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            2950..4671
                     /locus_tag="TU746_001979"
     CDS             2950..4671
                     /locus_tag="TU746_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0892263.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            4673..5836
                     /locus_tag="TU746_001980"
                     /pseudo
     CDS             4673..5836
                     /locus_tag="TU746_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            5988..6764
                     /locus_tag="TU746_001981"
     CDS             5988..6764
                     /locus_tag="TU746_001981"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL0892264.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            6757..7722
                     /locus_tag="TU746_001982"
     CDS             6757..7722
                     /locus_tag="TU746_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL0892265.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            7818..8477
                     /locus_tag="TU746_001983"
                     /pseudo
     CDS             7818..8477
                     /locus_tag="TU746_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
BASE COUNT         2695 a         1469 c         1887 g         2457 t
ORIGIN      
        1 ttatcgtgat agctgcctgg ggctggctgc taatatgata ggggaaaaca agagggttat
       61 tattattagc atgggctttg tggatttggt gatgtttaat cctgtattaa ttgctaagcg
      121 tgaagcgttt gaggcagagg aatcctgcct atcactaatc ggccaacgta agacaaagcg
      181 ttatcaggag atcaaggttg attaccttga tgcacattgg cacaagaaat ccctgagatt
      241 gacaggcctg cctgcacaaa tctgccagca tgagctggat catctggagg gcatattgat
      301 ttaaatcatg accacccgtt agtgaactgc accccaaaag ttagacagaa aatctaacga
      361 atgagggcag tccatagatg ggtggtttat ttgtcttgct caacaggtgc gaaacaaata
      421 aacgtcacat aaatcagaaa accggctgta tgcttaagat acagtcggtt attgctgtta
      481 tggctaggac gattttattg gccttccttt ttcttgaaaa ggctagtacc agttaaggtt
      541 agtagtccta ggattgtcat ggcagcagca gaatgctggc ttgttcctgt tgctggtaag
      601 gcagcattag cttgcttttt agctgctaga ggcttgatgc ttgtggcagg attagcattt
      661 tgagcaggcg taaataggtc agagacaagc tcagtagcaa gcaccttgcc ctcacgattc
      721 ttaaagacgc ggttgatgat ctcgtgcttg ccggtatgat cactttgagt agagccttca
      781 agactggcag tgacataggt tttcacaccg ttaataccag cacttacagt ctttccagct
      841 gcttcaaggt ccttgatgta ttcgataaag acctcagtat caggattaat ggctcctagt
      901 agcttagcgt ccttaaagac ggagaagcca tcaccaccgc catataggaa gtcgttgatg
      961 attagggtgt attgagctgc tggatcaatt tcttcaccat tatctttata agcctttact
     1021 accttaaacg gtgttgaagg atcgttagcc tcattagctg tataagtgta tttgagtcca
     1081 gacatttgaa ggaagtattt ttggtcttca tcgtattgtt ggttcaagac atcatagatt
     1141 tgttggccag tcatttgaac gacctgaaga atattgccaa atggttgaac agcctgtgca
     1201 gctccccagg taatggtttg atcctctttg accaccaagt cagcgcgaat accgccatta
     1261 tttgtcatgg caaaatcaac atgagggaag gtttttctac caatggttaa ttgggcagtt
     1321 gttatcaaat tgccaacagg agattccttg tcttcgtttt ctgttttaga aatcgttgaa
     1381 gaggtagctg ctgtaccgat ctttagctcg gtaacggttt tgacaatgtc attggcttga
     1441 tcaacaatgg cttgaatgtc ggcattgcct gtttttatgc caggagcaac ggcaatgacc
     1501 tttgcttcag gagtggctac aaaatcattg aggtcagtgt ctagtgttcc acgaacatct
     1561 gcataggctt tcccctgtga aacagcctga acgacacgtg ttgtgccaat ggtaccgttg
     1621 gtgtattggt ggttgtgacc agcaaagaca atatccacac tatgctcagg ataaagctgg
     1681 ttaacctttt ccataactgc tgccatctca tcatgaacta ccccgttatc acttgttgct
     1741 gggatatgag ctaggacaac aatcgcattg acctgctgct cttggagctc tttagcatat
     1801 ttaacgatgg tttctgcaga gtctaggtaa tcatattgtt cataattttg ttttaggaca
     1861 aggtttggaa tttctgttgt cacaacaccg ataaagccca ccttgactga cttatcatta
     1921 actgggactt ctttgacagc ataaggcttc cagccaaaag gaatcgtgtt ggtctccttg
     1981 tcaacgacat ttgcaatgac aagggtttga tttgaagctt catgctcgta ttgcttagta
     2041 atgtcgttga tagctgagtc ttcagcaggt gcagtgcctg tcatgatacg gttgaattca
     2101 gctaagccct catcgaattc gtgattccca agggttccgt attcaaagcc catctggttg
     2161 aataccttaa ccgttggctc gtcctgtaat agtccagaat tagcaggact agctccgacc
     2221 atatctcctg gttgaacacg aatgcttgtc ccatctgggc ttgtttgctt aaagtcagcc
     2281 tctgcatcgt ccagataagc agctaattgt gctgcggtac cagcgttaga tacctttcct
     2341 tctggcatgt aggcagagcc ggttgtgtct aaggcaccat gaaagtcatt gacaccaaga
     2401 aattgcacgt ctacctgatc ggcctgcacg ccggttacta gcatagaaac tccggcaaag
     2461 acaccaagaa cactactttt taaaacaaaa tgctttttca taaacgctcc taaaagttta
     2521 aagtattgtc acaagttaag tgtactatta tttaaatgag aattcaacaa aaattaataa
     2581 aaaagctaac aaaaattcaa cgatagcgtt tgctaatcac tgaaaacgtt taaaatgcaa
     2641 acattggaag cgttttttgt aaaaaaatag aagaactatc caaaaaaggc tttacaagcc
     2701 cagtattcta tgataagatg ttaggcagat taaaagaaag gagaaattaa taatgatccg
     2761 tttcattcaa ctatttaacc attattacga tagtctcctt tctaaccaaa acagttagtt
     2821 tcttttagtt tcactaaata gaaatagtag agcccgcggt aggaaggata tcttattgcg
     2881 ggctttttgt gtgcaaaaat cctattttaa gacagcttga aataggttag ttcagaaatg
     2941 gaggatatga tgctgacctt aattgttcaa catattaagc aaaagaaatg gatttatatc
     3001 cttattgcaa tgactttagt gatatatgat gcctcacttg tgataccaac aagggttatt
     3061 caagacttgg ttgatttgat gtcaaggcat cagctaagct caggggcatt ggtgaggcat
     3121 gttatcattc ttttggctac ggcagtagtg tcttatgggg ttgcttattt gtggcatctt
     3181 catttatttc aggaggcagt tcattttaag tttgatattc agcagcgtgc ctttcgaaag
     3241 cttgttttta tgagaacgcc tttttatgag aaatttcgct caggtgacat gatcacgcgt
     3301 ttttcaacag atgtcgaagc acttatggac cttatcggct atggcttgat gattatccta
     3361 tatgctggtg gtatgattgc ttttattatt ccgaccatgt ttttgatttc ttggaaaatg
     3421 accttgatag gaatagtacc gattttgctt atgatggtga tgatctatgg tgtgacgaaa
     3481 aagcaagagc atttggttga agaggcgcgt gaggcgattt caagccttag tgatgaggta
     3541 ctagaaaccg ttgagggcat tagagtgatg cgtgcttaca gtaaaaaaga ttatttggca
     3601 cttcattttg ctcaaaagac tcagaatttg gcagataaat ggaatcaggt ggccaagtat
     3661 cgtgccttgt actttcctct ttacagcgtc atgattgcca ttagtacagt aatcatttta
     3721 atggtaggcc tacagctcat agcaagctca gaggtaacac ttggtcaagt cattgcgctg
     3781 cagctttatc tggtgtcttt ggtggagccc tttggcatgc tgtcagactt tattttggtt
     3841 tatcagacag gaaagacctc ttttggtaag attaatgaac tcatcgaaac aagtgatgat
     3901 atggagcctg atggccagct tgagttagag agctttgatc agattgcttt tatagactat
     3961 agctttacct atgccaatag ttctaggcct agcttagaaa agatcaattt aaccctgaaa
     4021 aagggacaaa ccttagggat tgttggtaaa acaggctctg gtaaaacaac ccttgtcagg
     4081 cagtttttga gacaataccc tcttgggcag gggcagctga tgattaatca tcgtagtgtc
     4141 ttggattata agcgtcaatc acttgagcgt caaattggct atgtgccaca ggagcatatc
     4201 ctgttttcaa aaacggttgc tcaaaacatt gcgatgggga aaaaggcagc tacaactgag
     4261 gaaatcttgg aggcgattga aactgcggcc tttacgcgtg atgttcaagg aatggcaaag
     4321 ggcttggata ctgagattgg agagcgtggt ctgtctattt caggaggtca aaagcagcgt
     4381 atttcgattg ccagagcctt tttgtcccag ccagatttgc tgattttaga tgattccctg
     4441 tcggcagttg atgctagaac agagactgat attattcgac acattcaaga cgaaagaaag
     4501 ggaaagacaa cacttattgt tagccatcgc ttgtctgcga ttcagcatgc cgattgggtt
     4561 attgttctgg atcaggggca gatagtagag gaaggtcagc cccaacaact tttagctcag
     4621 aagggctggt attatgaaca gtaccagcgt cagcaggctc aggaggttta agatgaccct
     4681 atttataaaa ttaataaaag aaattaaagc tgtgaccttg gctttttccc tggcaatagg
     4741 ctttttgcta gtggcaacag ctggaggtca gatggctccc ttattgttgc aacaaacgat
     4801 tgatcattac ttgactccga tagctagagg aaaagaggta ccgattgaag gctttcagcg
     4861 cttgctcctg ctgtatttgc tgttaattgt gataacagca gttttgcgtt atatctctta
     4921 tcgaatgctg gtttattcct ctaataggat cgttgctaat cttcgtaatc gagcctttga
     4981 tgtcatgcag aggctgccga tagcttattt tgatcatcag cctgcaggaa agattgcaac
     5041 taggattgtt aatgatactg aaaccctgaa gaatcaattt tatgataacc ttttgtctca
     5101 aattattgtc agtctttcac aaattatttt tatttatgtg gtgatgattt accttgatgt
     5161 gaagtcaggc ttgctgttgc tgcttattat gccactcttt tatggcatgc aatggctgta
     5221 taaaagcttg actgaccagc caatgaagga tttttatcag gctaggagcg ctgtcaacac
     5281 acaagtcaac gaaaccatga atggtgtttc tattattcag ctttatcatc aagaggatac
     5341 gatcttagag gaatttgaag agcagatcca ccagatgaaa acagctgatg ataggattat
     5401 ttttgcagag tcagttgctt catggaccct gacggaattg gtaaagtatg gcatgattgc
     5461 cgctattttg gctgttattg gttaccagtt cttgcagggg agatcaggca tcacagttgg
     5521 taagctcttt atttacgtca attatttgct gcgcttgttt gatttattaa gtatgctggt
     5581 taggcagcta cctaatattc agcgctcaac agcgacagga acgcgcctaa tgaagctgct
     5641 tgaggcgcag acagagccgg ataaagcacg agcaattgag ctaacagatg gtactgtgga
     5701 ttttaccaag gtgtattttg cttacgaaaa tggcaagaca gttttatctg atattaccat
     5761 tcatgctgat aaaggggaga cggttgccct agtagggcat actggctctg gggacaatgc
     5821 tataatgatg atagtacaat aaatccaagt aaaatcaatg gttaaaggct tccgcaaaac
     5881 ttttaaactt gatgatggat tgaggctatc atcttttttt atatctaaaa ttatataaaa
     5941 gtatagcata aaatgaaatc tctgtataga gaagaaggag ggactttatg gcagaagtga
     6001 taaccatagc caatcgaaaa ggcggagttg gaaaaacaac tacaactcta aaccttgcct
     6061 attcactaaa agaactgggg aaaaaagtat tagtcattga ccttgatcca caagctaatc
     6121 ttacaagatg ttttgatatg ggaaatacag aaaatataaa aaccataggg catttgttaa
     6181 tggtagaact ggaggaagaa gaaagctatt tggtagaggg ctataccaaa tcttatgatg
     6241 agatagatat tatcccctca agcattttct tatccgccgt tgaaacacaa atgagagcag
     6301 aaacaggaag tgaacgtata ttatcggaaa ttattaggag ggtaaaagag aattatgact
     6361 atattctcat agatacatca ccatcactta gtgttttgac tataaatgct ctttgtgcct
     6421 cagacagtgt ccttatagta gcggatacac agctgttcgc agttgttgga atcaatgaac
     6481 ttttaaaaac tgttcaaaaa ataaaaaaga gagtgaatcc gaaactgaaa gtgcagggga
     6541 ttttactaac catgtgtgag aatagaacca atctgtccaa aacactgatg gagcaagtag
     6601 aagaaatgtt ccaaaagaaa atcaaggtct ttcaaaccaa aattccgaaa acagttaaag
     6661 ttggggaagc catctatagc gggcaaagca taaaaaaata tgcaaaaggc agtagtgtag
     6721 acattgccta tgacaatctg gcaaaggaga tctgctatga gtaaaaaact tctaaagaga
     6781 gaaatcaccg atgccgtaga ttttttgctt gatgatggaa atgccttgga acaaggaaat
     6841 atacagaata tagaacttga tttgcttgaa aattatcata atcatccgtt tactttatat
     6901 acaggtaaga gattagacga tatggtagag agcattaagg aaaacggagt tcttaatcca
     6961 attatcgtct tgaaaaaaga taacaactat gaaatacttt ccggacacaa tagagtaaat
     7021 gcagcaagaa ttacaaaaat aaaaagtatt ccttgtattg ttaaagaaaa tctaacggat
     7081 aaagaagcct atacctatgt aattgaaaca aaccttatac agcgttcttt ctccgattta
     7141 ctgccgacgg aaaaagccct tgttcttaaa atgagatatg aaaaaatagc aagtcagggc
     7201 aagagaaatg atttgcaaaa ggagataaac aatttagatc agggaattat agaaaaggaa
     7261 agtaaagagg aagataaaat agacagcaga aaaacacttg gaaaagaata taatctttca
     7321 ggggcatcta ttgcaaggta cctaagatta aatgaattat ctaagtcttg gaaaaaagat
     7381 gtggatgaag ataaaatagg tttgacgatg gcagtagatt tatcctatct ttccaaagaa
     7441 atacaggaat atctgtatca gaagtgcgaa gaattggaac taagtttaaa accaagcgat
     7501 gccaaagcac tccatctgat gaacagacaa gaagatctga atcaagagat ggttataaca
     7561 tacttgctga acttgaaaaa aacgaaggta aaaaagtatc agaatatcaa actatctcag
     7621 agtgtctata aaaagttttt tcatgatgaa aggaaagaag atgtagaaga aattatagaa
     7681 aaagcattgg aaatttactt taaggaatat attggtcagt gaaaagacaa aattataaat
     7741 ttaaggtata atataaggta ttaaaaaggg aaaagacctg tttaacagga taagatataa
     7801 aagaggcagg tgtcagaatg gacgaaataa aattgtatga aaataaagag atacgctcca
     7861 tttgggacga agaaaaagaa gagtggtatt tttcagtagt cgatgtagtt ggagttttga
     7921 cagaacaaga aaacgtaaga ggtgctagta cctattgggc tgtactaaaa aagagattaa
     7981 aagaagaagg aaatgaactg cttacaattt gtaagcagtt gaaaatgaaa gcaacagatg
     8041 gaaaaatgcg tttaactgat gtagcagata tgcaaggaat attccgtatt atccagtcca
     8101 tcccatcccc taaagcagaa ccttttaagt tatggcttgc tgaggttgga aaagaacgaa
     8161 ttgatgaaat tatcgatcct gaacttacga ttgacagagc cttagaaact tatctaaaga
     8221 agggatatac acgtgagtgg ataaatcaaa gacttcaagc cattcaggta agaaaagaac
     8281 tgactgatgc ttgggatgac catgggatac aaaaaggcaa agaatacgca attcttactg
     8341 atgaaatcac caaagcatgg tccggaatga caacaagagg ttataaaaat ctgaagggtt
     8401 tgaaaaagga aaatctaagg gataatatga ccactcttga aatagttctt aatatgcttg
     8461 cagaagccac aacaacaaac gcattaaagc aaagctaaaa ggacttag
//
